Data / Nonprofits / South Carolina
Nonprofits in South Carolina: 32,575 registered with the IRS
32,575 nonprofits are registered with the IRS in South Carolina, 28,680 of them 501(c)(3) charities; the 7,483 that report revenue took in $41.37 billion. The most are in Edgefield (3,977), Columbia (2,773), Greenville (1,653). The largest by revenue: Advanced Technology International ($4.87 billion), Prisma Health - Upstate ($3.61 billion), Prisma Health-Midlands ($2.08 billion).
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By cause
- Religion-related 3,557
- Education 2,688
- Human services 2,596
- Recreation and sports 1,359
- Arts, culture and humanities 1,356
- Community improvement and capacity building 1,150
- Philanthropy, voluntarism and grantmaking foundations 1,086
- Youth development 843
- Animal-related 733
- Public and societal benefit 659
- Health care 595
- Housing and shelter 475
- Mental health and crisis intervention 399
- Environment 355
- Food, agriculture and nutrition 283
- Public safety, disaster preparedness and relief 260
- Mutual and membership benefit 237
- Crime and legal-related 217
- Diseases, disorders and medical disciplines 195
- International, foreign affairs and national security 189
- Employment 143
- Civil rights, social action and advocacy 115
- Medical research 82
- Science and technology 66
- Social science 17
By city
- Edgefield 3,977
- Columbia 2,773
- Greenville 1,653
- Charleston 1,343
- Spartanburg 687
- Myrtle Beach 649
- Rock Hill 635
- Summerville 634
- Florence 561
- Mt Pleasant 533
- N Charleston 529
- Anderson 514
- Lexington 496
- Aiken 493
- Fort Mill 473
- Sumter 469
- Simpsonville 420
- Greer 374
- Orangeburg 367
- Conway 348
- Greenwood 339
- Beaufort 324
- West Columbia 316
- Hilton Head 300
- Bluffton 274
- Easley 271
- Lancaster 261
- Seneca 228
- Irmo 228
- Moncks Corner 219
- Blythewood 215
- Camden 212
- Georgetown 209
- Goose Creek 208
- Gaffney 205
- Taylors 200
- North Augusta 197
- Hartsville 177
- Johns Island 169
- Clemson 163
- Clover 151
- Chapin 146
- Laurens 127
- Walterboro 127
- Elgin 126
- York 125
- Chester 124
- Piedmont 117
- Pawleys Isl 116
- Kingstree 115
- Boiling SPGS 114
- Travelers RST 114
- Union 112
- Newberry 111
- Inman 111
- Darlington 106
- Clinton 105
- Ridgeland 102
- Pickens 102
- Manning 99
- Lake City 98
- N Myrtle BCH 98
- Murrells Inlt 96
- Belton 92
- Fountain Inn 90
- Winnsboro 90
- Mauldin 89
- Ladson 88
- Cayce 87
- Barnwell 87
- Little River 85
- Bennettsville 85
- Loris 84
- Marion 84
- Abbeville 84
- Westminster 83
- Dillon 83
- Hopkins 79
- Indian Land 77
- Chesnee 76
- Woodruff 73
- Bishopville 70
- Moore 69
- Lugoff 68
- Andrews 68
- Cheraw 67
- Daniel Island 66
- Duncan 66
- Pelzer 65
- Graniteville 65
- Pendleton 65
- Walhalla 62
- Liberty 60
- Leesville 60
- Mullins 59
- St Matthews 57
- Honea Path 57
- Chesterfield 55
- Kershaw 54
- Timmonsville 54
- Landrum 53
- Hemingway 52
- North Charleston 52
- Hollywood 51
- Ridgeville 51
- Central 51
- Saluda 50
- St Helena Is 49
- Gilbert 49
- Lyman 48
- Lake Wylie 48
- Longs 47
- Williamston 47
- Pageland 47
- Eastover 46
- Blacksburg 46
- Hardeeville 45
- MC Cormick 45
- Prosperity 44
- Ninety Six 43
- Hanahan 42
- Salem 42
- Gaston 40
- Roebuck 39
- Okatie 39
- Campobello 38
- Ridgeway 38
- Gray Court 37
- Bamberg 37
- Edisto Island 37
- Holly Hill 37
- Hampton 36
- Swansea 36
- Denmark 36
- Summerton 35
- Latta 34
- Surfside BCH 34
- Aynor 33
- Isle of Palms 33
- Tega Cay 32
- Batesburg 32
- Richburg 31
- Effingham 31
- Lamar 31
- Wagener 30
- Dalzell 30
- Iva 30
- Hilton Head Island 29
- Folly Beach 29
- Blackville 28
- Ravenel 28
- Allendale 28
- Heath Springs 28
- Huger 27
- Wellford 27
- Varnville 27
- Saint Stephen 27
- Ware Shoals 27
- Sullivans Is 26
- Yemassee 26
- Awendaw 26
- Estill 26
- Mount Pleasant 25
- Johnsonville 25
- West Union 25
- Rembert 25
- Marietta 25
- Little MTN 25
- Jackson 24
- Beech Island 24
- Great Falls 24
- Johnston 24
- Cross 23
- Williston 23
- McClellanvle 23
- Cowpens 23
- Warrenville 22
- Port Royal 21
- Pelion 21
- Townville 21
- Pamplico 21
- North 20
- Saint George 20
- Fair Play 20
- Pacolet 20
- Bonneau 20
- Jefferson 20
- Bowman 19
- Trenton 19
- Kiawah Island 19
- Hodges 19
- Whitmire 19
- Santee 19
- Shaw Afb 18
- Scranton 18
- Pauline 18
- Nichols 17
- Sunset 17
- Cottageville 17
- Six Mile 17
- Lake View 16
- Coward 16
- Pinewood 16
- Greeleyville 16
- Salters 16
- Catawba 16
- Starr 16
- Pineville 15
- Enoree 15
- Dorchester 15
- Cameron 15
- St George 15
- New Ellenton 15
- Mayesville 14
- Due West 14
- Gadsden 14
- Cope 14
- Eutawville 14
- Lynchburg 14
- Drayton 14
- Seabrook 14
- Sheldon 13
- Ridge Spring 13
- Jonesville 13
- Salley 13
- Mountain Rest 13
- Pomaria 13
- Langley 13
- Hamer 12
- McBee 12
- Windsor 12
- Bethune 12
- Cross Hill 12
- Ballentine 12
- Wadmalaw Is 12
- Elloree 12
- Turbeville 12
- Edgemoor 12
- Calhoun Falls 12
- Fairfax 12
- Green Sea 11
- Alcolu 11
- Branchville 11
- Norway 11
- Joanna 11
- Waterloo 11
- Neeses 10
- Patrick 10
- Sandy Springs 10
- Islandton 10
- Sharon 10
- Vance 10
- Cassatt 10
- North Myrtle Beach 10
- McColl 9
- Little Rock 9
- Blackstock 9
- Murrells Inlet 9
- Ruffin 9
- Olanta 9
- Cordova 9
- Wallace 9
- Buffalo 8
- Smoaks 8
- McConnells 8
- Donalds 8
- Fort Lawn 8
- Harleyville 8
- Jamestown 8
- Galivants Fry 8
- Daufuskie Is 8
- Chas Afb 8
- Society Hill 8
- Wando 8
- Troy 8
- Cades 7
- Wedgefield 7
- Ehrhardt 7
- Surfside Beach 7
- Belvedere 7
- Brunson 7
- Una 7
- Adams Run 7
- Mount Croghan 7
- Clarks Hill 7
- Batsbrg Levil 7
- Tamassee 6
- Plum Branch 6
- Springfield 6
- Clio 6
- Norris 6
- Fork 6
- McCormick 6
- Reidville 6
- Tigerville 6
- Pawleys Island 6
- Clearwater 6
- Gresham 6
- Monetta 6
- Fripp Island 6
The 100 largest by revenue
| Organization | City | Category | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|---|
| Advanced Technology International | Summerville | Science and technology | 501(c)(3) | 1998 | $4.87 billion | $2.19 billion | 2025-09 |
| Prisma Health - Upstate | Greenville | Health care | 501(c)(3) | 2016 | $3.61 billion | $1.41 billion | 2025-09 |
| Prisma Health-Midlands | Greenville | Health care | 501(c)(3) | 1997 | $2.08 billion | $1.06 billion | 2025-09 |
| Lexington Health Inc | West Columbia | Health care | 501(c)(3) | 2020 | $1.77 billion | $2.30 billion | 2025-09 |
| Central Electric Power Cooperative Inc | Columbia | 501(c)(12) | 1954 | $1.61 billion | $558.9 million | 2024-12 | |
| McLeod Regional Medical Center of the Pee Dee Inc | Florence | Health care | 501(c)(3) | 1975 | $1.49 billion | $3.03 billion | 2025-09 |
| Prisma Health-University Medical Group | Greenville | Health care | 501(c)(3) | 1998 | $925.8 million | $132.7 million | 2025-09 |
| Anmed Health | Anderson | Health care | 501(c)(3) | 1937 | $854.6 million | $1.54 billion | 2024-12 |
| St Francis Hospital Inc | Greenville | 501(c)(3) | 1946 | $850.9 million | $586.8 million | 2024-12 | |
| Bon Secours-St Francis Xavier Hospital Inc | Charleston | Health care | 501(c)(3) | 1998 | $620.6 million | $319 million | 2024-12 |
| Berkeley Electric Cooperative Inc | Moncks Corner | 501(c)(12) | 1943 | $594.9 million | $791.2 million | 2025-12 | |
| The Blackbaud Giving Fund | Daniel Island | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2014 | $545.8 million | $56 million | 2025-12 |
| Roper Hospital Inc | Charleston | Health care | 501(c)(3) | 1955 | $539.5 million | $343.1 million | 2024-12 |
| Apella Health Management Inc | Spartanburg | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2017 | $524.7 million | $101.4 million | 2025-09 |
| McLeod Loris Seacoast Hospital | Florence | Health care | 501(c)(3) | 2013 | $466.9 million | $486.4 million | 2025-09 |
| Conway Hospital Inc | Conway | Health care | 501(c)(3) | 1955 | $416.5 million | $864.7 million | 2025-09 |
| Prisma Health Medical Group-Midlands | Greenville | Education | 501(c)(3) | 2014 | $401.1 million | $113.4 million | 2025-09 |
| McLeod Health | Florence | Health care | 501(c)(3) | 2003 | $399.6 million | $192.2 million | 2025-09 |
| Prisma Health | Greenville | Health care | 501(c)(3) | 2017 | $339.5 million | $4.64 billion | 2025-09 |
| Charter Institute at Erskine | Columbia | Education | 501(c)(3) | 2019 | $299.9 million | $17.4 million | 2025-06 |
| Furman University | Greenville | Education | 501(c)(3) | 1937 | $296.9 million | $1.45 billion | 2025-06 |
| Georgetown Memorial Hospital | Georgetown | Health care | 501(c)(3) | 1959 | $268.1 million | $63 million | 2025-09 |
| Georgetown Hospital System | Georgetown | Health care | 501(c)(3) | 2003 | $265.8 million | $585.1 million | 2025-09 |
| Roper St Francis Healthcare | Ladson | Health care | 501(c)(3) | 1998 | $259.4 million | $2.44 billion | 2024-12 |
| Prisma Health - Blount Memorial Hospital Inc | Greenville | Health care | 501(c)(3) | 2025 | $240.5 million | $166.6 million | 2025-09 |
| Greenville Health Corporation | Greenville | Health care | 501(c)(3) | 1999 | $230.3 million | $66.7 million | 2025-09 |
| Waccamaw Community Hospital | Georgetown | Health care | 501(c)(3) | 2003 | $225.7 million | $295.6 million | 2025-09 |
| Horry Electric Cooperative Inc | Conway | Public and societal benefit | 501(c)(12) | 1942 | $220.6 million | $516.4 million | 2025-12 |
| MPD Electric Cooperative Inc | Florence | Public and societal benefit | 501(c)(12) | 2023 | $214.9 million | $401.9 million | 2024-12 |
| Roper Saint Francis Physicians Network | Ladson | Health care | 501(c)(3) | 2009 | $213 million | $94.4 million | 2024-12 |
| McLeod Physician Associates II | Florence | Health care | 501(c)(3) | 2006 | $210.1 million | $47.2 million | 2025-09 |
| Blue Ridge Electric Cooperative | Pickens | 501(c)(12) | 1942 | $208 million | $580.1 million | 2024-12 | |
| Hopehealth Inc | Florence | Health care | 501(c)(3) | 1995 | $200.5 million | $141.3 million | 2024-12 |
| Palmetto Electric Cooperative Inc | Ridgeland | 501(c)(12) | 1944 | $194.8 million | $321.1 million | 2024-12 | |
| Mid-Carolina Electric Cooperative Inc | Lexington | 501(c)(12) | 1942 | $179.5 million | $419.3 million | 2025-12 | |
| Anderson University | Anderson | Education | 501(c)(3) | 1935 | $177.4 million | $293.1 million | 2025-05 |
| Wofford College | Spartanburg | 501(c)(3) | 1937 | $166.4 million | $804.2 million | 2025-06 | |
| Laurens Electric Cooperative Inc | Laurens | Public and societal benefit | 501(c)(12) | 1942 | $163.1 million | $335.7 million | 2024-12 |
| Santee Electric Cooperative Inc | Kingstree | 501(c)(12) | 1943 | $156.3 million | $305.6 million | 2025-12 | |
| Bon Secours Medical Group Greenville Specialty Care LLC | Greenville | Health care | 501(c)(3) | 2023 | $155.6 million | $24.4 million | 2024-12 |
| Roper St Francis Hospital-Berkeley Inc | Summerville | Health care | 501(c)(3) | 2012 | $152.1 million | $281.9 million | 2024-12 |
| York Electric Cooperative Inc | York | 501(c)(12) | 1975 | $151.2 million | $282.1 million | 2024-12 | |
| The Blood Connection Incorporated | Piedmont | Health care | 501(c)(3) | 1978 | $149.7 million | $107.7 million | 2025-08 |
| Aiken Electric Cooperative Inc | Aiken | 501(c)(12) | 1943 | $145.7 million | $580.5 million | 2024-12 | |
| Roper St Francis Mount Pleasant Hospital | Mt Pleasant | Health care | 501(c)(3) | 1936 | $139.7 million | $86.6 million | 2024-12 |
| The Medical University of South Carolina Foundation | Charleston | Medical research | 501(c)(3) | 2024 | $136.7 million | $944.2 million | 2025-06 |
| Charleston Southern University | N Charleston | Education | 501(c)(3) | 1964 | $125.2 million | $237.6 million | 2025-05 |
| Clemson University Foundation | Clemson | Education | 501(c)(3) | 1968 | $118.6 million | $1.55 billion | 2025-06 |
| Bju Inc | Greenville | Education | 501(c)(3) | 2003 | $114.8 million | $108.7 million | 2025-05 |
| Black River Electric Cooperative Inc | Sumter | 501(c)(12) | 1942 | $105.8 million | $140.8 million | 2025-12 | |
| McLeod Health Clarendon | Florence | Health care | 501(c)(3) | 2016 | $102.5 million | $49.7 million | 2025-09 |
| Fairfield Electric Cooperative Inc | Blythewood | 501(c)(12) | 1942 | $99.9 million | $154.3 million | 2025-12 | |
| Welvista | Columbia | Health care | 501(c)(3) | 1998 | $96 million | $48.7 million | 2025-06 |
| Lutheran Homes of South Carolina Inc | Irmo | Human services | 501(c)(3) | 1942 | $94.6 million | $124.5 million | 2025-09 |
| Lowcountry Food Bank Inc | Charleston | 501(c)(3) | 1984 | $90.1 million | $35.1 million | 2024-12 | |
| McLeod Medical Center Dillon | Florence | Health care | 501(c)(3) | 2003 | $87.6 million | $152.5 million | 2025-09 |
| Presbyterian Communities of South Carolina | Columbia | Human services | 501(c)(3) | 1959 | $87.6 million | $183.7 million | 2025-12 |
| Caresouth Carolina Inc | Hartsville | Health care | 501(c)(3) | 1980 | $86.2 million | $48.5 million | 2025-05 |
| University of South Carolina Educational Foundation | Columbia | Education | 501(c)(3) | 1962 | $85.1 million | $856.9 million | 2025-06 |
| McLeod Health Cheraw | Florence | Health care | 501(c)(3) | 2015 | $84.5 million | $40.8 million | 2025-09 |
| Greater Myrtle Beach Collaborative | Myrtle Beach | 501(c)(6) | 1984 | $83.6 million | $41.2 million | 2024-12 | |
| Bishop Gadsden Episcopal Retirement Community | Charleston | Human services | 501(c)(3) | 1943 | $83.5 million | $387.5 million | 2025-12 |
| Musc Affiliate Physicians | Charleston | Mental health and crisis intervention | 501(c)(3) | 2023 | $82.1 million | $31.8 million | 2025-06 |
| Eau Claire Cooperative Health Center Inc | Columbia | 501(c)(3) | 1993 | $76.9 million | $33.7 million | 2024-12 | |
| Presbyterian College | Clinton | Housing and shelter | 501(c)(3) | 1944 | $76.7 million | $171.8 million | 2025-06 |
| Genesis Healthcare Inc | Columbia | Health care | 501(c)(3) | 2010 | $76.3 million | $166.8 million | 2025-06 |
| Agfirst-Fcbt Employee Welfare Benefit Trust | Columbia | Mutual and membership benefit | 501(c)(9) | 1995 | $74.2 million | $6.4 million | 2024-12 |
| North Greenville University | Tigerville | Education | 501(c)(3) | 1946 | $72.4 million | $118.7 million | 2025-05 |
| South Carolina First Steps To School Readiness Board of Trustees | Columbia | Education | 501(c)(3) | 2000 | $72.4 million | $34.7 million | 2025-06 |
| Southern Mutual Church Insurance Company | Columbia | Mutual and membership benefit | 501(c)(4) | 1983 | $72 million | $81.1 million | 2025-12 |
| Iptay | Clemson | Youth development | 501(c)(3) | 2014 | $71.6 million | $143.9 million | 2025-06 |
| Columbia International University | Columbia | Education | 501(c)(3) | 1937 | $71 million | $104.5 million | 2025-06 |
| Edisto Electric Cooperative Inc | Bamberg | Public and societal benefit | 501(c)(12) | 1942 | $69.6 million | $254 million | 2025-12 |
| Claflin University | Orangeburg | Education | 501(c)(3) | 1946 | $69.3 million | $183.2 million | 2025-06 |
| Newberry College | Newberry | Education | 501(c)(3) | 1940 | $66.3 million | $84.1 million | 2025-06 |
| Lynches River Electric Cooperative Inc | Pageland | 501(c)(12) | 1942 | $66.1 million | $148.7 million | 2024-12 | |
| Palmetto Goodwill | Charleston | Human services | 501(c)(3) | 2015 | $65.1 million | $137.2 million | 2024-12 |
| Broad River Electric Cooperative Inc | Cowpens | 501(c)(12) | 1942 | $62.3 million | $166.7 million | 2024-12 | |
| Tri-County Electric Cooperative Inc | St Matthews | 501(c)(12) | 1942 | $62 million | $177.3 million | 2025-12 | |
| South Carolina Connections Academy Inc | Columbia | Education | 501(c)(3) | 2010 | $61.8 million | $34.8 million | 2025-06 |
| Goodwill Industries of Upstate Midlands South Carolina Inc | Greenville | Employment | 501(c)(3) | 1973 | $61.6 million | $115.7 million | 2025-06 |
| Newberry Electric Cooperative Inc | Newberry | 501(c)(12) | 1942 | $58.7 million | $121 million | 2025-12 | |
| South Carolina Student Loan Corporation | Columbia | Public and societal benefit | 501(c)(3) | 1975 | $58.4 million | $892.3 million | 2025-06 |
| Charleston Educational Excellence Financing Corporation | Charleston | Recreation and sports | 501(c)(3) | 2006 | $57.3 million | $326.1 million | 2025-06 |
| Gamecock Club | Columbia | Education | 501(c)(3) | 2024 | $56.4 million | $32.5 million | 2025-06 |
| National Wild Turkey Federation Inc | Edgefield | Environment | 501(c)(3) | 1993 | $54.3 million | $31.8 million | 2025-08 |
| Benedict College | Columbia | Education | 501(c)(3) | 1945 | $52.8 million | $143.9 million | 2024-06 |
| We Are Sharing Hope SC | Charleston | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2006 | $52.3 million | $60.5 million | 2025-12 |
| Converse University | Spartanburg | Education | 501(c)(3) | 1937 | $50.7 million | $175 million | 2025-06 |
| Spartanburg County Foundation | Spartanburg | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1948 | $50.6 million | $280.4 million | 2025-12 |
| Harvest Hope Food Bank | Columbia | Food, agriculture and nutrition | 501(c)(3) | 1982 | $50.5 million | $30.4 million | 2024-06 |
| The Heron Institute | Greenville | Education | 501(c)(3) | 2017 | $49.9 million | $44.7 million | 2025-06 |
| Little River Medical Center Inc | Little River | Health care | 501(c)(3) | 1980 | $49.7 million | $34.4 million | 2025-05 |
| Musc Health Partners | Charleston | Health care | 501(c)(3) | 2020 | $49.4 million | $9.1 million | 2025-06 |
| South Carolina Episcopal Home at Still Hopes | West Columbia | Health care | 501(c)(3) | 1978 | $48.1 million | $201.2 million | 2025-09 |
| Erskine College | Due West | Education | 501(c)(3) | 1942 | $48 million | $76.8 million | 2025-06 |
| Central Carolina Community Foundation | Columbia | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1987 | $47.1 million | $264.3 million | 2025-06 |
| Meeting Street Schools | Charleston | Education | 501(c)(3) | 2007 | $46.8 million | $311.8 million | 2025-06 |
| Limestone University | Gaffney | Education | 501(c)(3) | 1946 | $46.5 million | $49.6 million | 2025-06 |
| Coastal Community Foundation of South Carolina Inc | N Charleston | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1982 | $46.3 million | $435.6 million | 2024-12 |
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.