Data / Nonprofits / South Carolina / Greenville
Nonprofits in Greenville, SC: 1,653 registered with the IRS
1,653 nonprofits are registered with the IRS in Greenville, SC, 1,464 of them 501(c)(3) charities; the 616 that report revenue took in $10.50 billion. The largest by revenue: Prisma Health - Upstate ($3.61 billion), Prisma Health-Midlands ($2.08 billion), Prisma Health-University Medical Group ($925.8 million). Most common causes: religion-related (190), education (167), human services (144).
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The 500 largest by revenue
| Organization | Category | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|
| Prisma Health - Upstate | Health care | 501(c)(3) | 2016 | $3.61 billion | $1.41 billion | 2025-09 |
| Prisma Health-Midlands | Health care | 501(c)(3) | 1997 | $2.08 billion | $1.06 billion | 2025-09 |
| Prisma Health-University Medical Group | Health care | 501(c)(3) | 1998 | $925.8 million | $132.7 million | 2025-09 |
| St Francis Hospital Inc | 501(c)(3) | 1946 | $850.9 million | $586.8 million | 2024-12 | |
| Prisma Health Medical Group-Midlands | Education | 501(c)(3) | 2014 | $401.1 million | $113.4 million | 2025-09 |
| Prisma Health | Health care | 501(c)(3) | 2017 | $339.5 million | $4.64 billion | 2025-09 |
| Furman University | Education | 501(c)(3) | 1937 | $296.9 million | $1.45 billion | 2025-06 |
| Prisma Health - Blount Memorial Hospital Inc | Health care | 501(c)(3) | 2025 | $240.5 million | $166.6 million | 2025-09 |
| Greenville Health Corporation | Health care | 501(c)(3) | 1999 | $230.3 million | $66.7 million | 2025-09 |
| Bon Secours Medical Group Greenville Specialty Care LLC | Health care | 501(c)(3) | 2023 | $155.6 million | $24.4 million | 2024-12 |
| Bju Inc | Education | 501(c)(3) | 2003 | $114.8 million | $108.7 million | 2025-05 |
| Goodwill Industries of Upstate Midlands South Carolina Inc | Employment | 501(c)(3) | 1973 | $61.6 million | $115.7 million | 2025-06 |
| The Heron Institute | Education | 501(c)(3) | 2017 | $49.9 million | $44.7 million | 2025-06 |
| National Council of Examiners for Engineering and Surveying | Science and technology | 501(c)(3) | 1953 | $45.7 million | $107.9 million | 2025-09 |
| Christ Church Episcopal School | Education | 501(c)(3) | 2001 | $44.1 million | $76 million | 2025-06 |
| Peace Center Foundation | Arts, culture and humanities | 501(c)(3) | 1987 | $41.9 million | $160.1 million | 2025-08 |
| Community Foundation of Greenville Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1971 | $37.6 million | $118.8 million | 2024-12 |
| St Francis Physician Services Inc | Health care | 501(c)(3) | 2006 | $36.9 million | $123.7 million | 2024-12 |
| Radio Training Network Inc | Religion-related | 501(c)(3) | 1985 | $36.3 million | $100.3 million | 2024-12 |
| Global Renewable Energy Education Network | Education | 501(c)(3) | 2013 | $35.9 million | $61.8 million | 2025-06 |
| Sunbelt Human Advancement Resources Inc | Education | 501(c)(3) | 1966 | $34.4 million | $19.6 million | 2025-09 |
| New Horizon Family Health Services Inc | Health care | 501(c)(3) | 1991 | $31.3 million | $23.3 million | 2025-01 |
| YMCA of Greenville | Human services | 501(c)(3) | 1937 | $29.8 million | $88.5 million | 2024-12 |
| Rolling Green Village | 501(c)(3) | 1979 | $29.1 million | $87.3 million | 2024-12 | |
| Upstate Senior Living Inc | Human services | 501(c)(3) | 2007 | $26.5 million | $136 million | 2024-12 |
| Miracle Hill Ministries Inc | Human services | 501(c)(3) | 1958 | $26.3 million | $45.8 million | 2025-06 |
| Legacy Early College | Education | 501(c)(3) | 2008 | $24.3 million | $17.7 million | 2025-06 |
| Greenville Country Club | 501(c)(7) | 1940 | $23 million | $49.4 million | 2025-12 | |
| Project Hope Foundation Inc | Human services | 501(c)(3) | 1998 | $21.8 million | $19.1 million | 2025-06 |
| Hollingsworth Funds Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1994 | $18.6 million | $406.7 million | 2024-12 |
| Visitgreenville SC | 501(c)(6) | 1985 | $15.9 million | $7.1 million | 2025-06 | |
| American Leprosy Missions Inc | International, foreign affairs and national security | 501(c)(3) | 1955 | $15.8 million | $15.8 million | 2025-06 |
| Blount Memorial Physician Group Inc | Health care | 501(c)(3) | 2026 | $15.6 million | $20.1 million | 2025-09 |
| St Josephs Catholic School Inc | 501(c)(3) | 1992 | $14.9 million | $22.8 million | 2025-06 | |
| Building Equity Sooner for Tomarrow | Education | 501(c)(3) | 2006 | $14.2 million | $294.4 million | 2025-06 |
| Aid Upstate | 501(c)(3) | 1988 | $12.2 million | $6.9 million | 2024-12 | |
| United Way of Greenville County Incorporated | 501(c)(3) | 1976 | $12.2 million | $25.6 million | 2024-12 | |
| Prisma Health-Upstate Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2024 | $11.6 million | $60.5 million | 2025-09 |
| National Association for Gun Rights Inc | Civil rights, social action and advocacy | 501(c)(4) | 2001 | $11 million | $3 million | 2024-12 |
| United States Endowment Forforestry and Communities Inc | Environment | 501(c)(3) | 2007 | $10.2 million | $292.5 million | 2024-12 |
| South Carolina Society for the Prevention of Cruelty To Animals | Animal-related | 501(c)(3) | 1949 | $9.5 million | $15.8 million | 2024-12 |
| South Carolina Manufacturing Extension Partnership | Community improvement and capacity building | 501(c)(3) | 1998 | $9.3 million | $5.4 million | 2025-06 |
| Homes of Hope Inc | Housing and shelter | 501(c)(3) | 1999 | $9.1 million | $59.6 million | 2025-08 |
| Naturaland Trust | Environment | 501(c)(3) | 1973 | $8.7 million | $58.2 million | 2025-03 |
| Institute for Child Success Inc | Social science | 501(c)(3) | 2010 | $8.4 million | $5.6 million | 2025-06 |
| Opportunity South Carolina | Community improvement and capacity building | 501(c)(3) | 2020 | $7.7 million | $86 million | 2024-12 |
| Greenville Free Medical Clinic | 501(c)(3) | 1988 | $7.7 million | $2.5 million | 2025-06 | |
| Greenville Housing Fund | Housing and shelter | 501(c)(3) | 2020 | $7.5 million | $75.6 million | 2024-12 |
| Meals On Wheels for Senior Citizens Endowment Fund Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1993 | $7.4 million | $22.1 million | 2025-12 |
| First Presbyterian Academy Inc | Education | 501(c)(3) | 2019 | $7.4 million | $10 million | 2025-06 |
| Upstate Forever | Environment | 501(c)(3) | 1998 | $7.3 million | $9.5 million | 2025-12 |
| Habitat for Humanity International Inc | Housing and shelter | 501(c)(3) | 1987 | $7.3 million | $7.4 million | 2025-06 |
| Greenville Technical Charter High School | Education | 501(c)(3) | 1999 | $7.1 million | $9.6 million | 2025-06 |
| Meyer Center for Special Children | 501(c)(3) | 1956 | $6.6 million | $10 million | 2025-06 | |
| Meals On Wheels of Greenville Inc | Food, agriculture and nutrition | 501(c)(3) | 1971 | $6 million | $20.4 million | 2025-12 |
| Lead Academy | Education | 501(c)(3) | 2009 | $6 million | $16.7 million | 2025-06 |
| United Housing Connections | Community improvement and capacity building | 501(c)(3) | 1997 | $5.6 million | $20.5 million | 2025-09 |
| Girl Scouts of South Carolina- Mountain To Midlands Inc | Youth development | 501(c)(3) | 1966 | $5.6 million | $17.2 million | 2025-09 |
| Carolina Elite Soccer Academy | Recreation and sports | 501(c)(3) | 1998 | $5.6 million | $9.4 million | 2025-06 |
| Poinsett Club | Recreation and sports | 501(c)(7) | 1953 | $5.6 million | $6.5 million | 2024-12 |
| Camperdown Academy Inc | Education | 501(c)(3) | 1987 | $5.4 million | $12.7 million | 2025-06 |
| Community Works | Housing and shelter | 501(c)(3) | 2008 | $5.3 million | $38.8 million | 2025-12 |
| Langston Charter Middle School Inc | Education | 501(c)(3) | 2006 | $5.2 million | $4.1 million | 2025-06 |
| Make-A-Wish Foundation of SC Inc | Health care | 501(c)(3) | 1985 | $5.1 million | $4.3 million | 2025-08 |
| Greenville Tech Foundation Inc | Education | 501(c)(3) | 1974 | $5.1 million | $48.5 million | 2024-12 |
| Set Free Alliance | International, foreign affairs and national security | 501(c)(3) | 2005 | $5 million | $480,036 | 2025-12 |
| Child Freedom Coalition Inc | 501(c)(3) | 1972 | $4.9 million | $1.1 million | 2025-12 | |
| Front Porch Housing | Housing and shelter | 501(c)(3) | 2022 | $4.7 million | $16.9 million | 2025-12 |
| Childrens Museum of the Upstate Inc | Arts, culture and humanities | 501(c)(3) | 2000 | $4.4 million | $30.6 million | 2024-12 |
| Mill Community Ministries | Human services | 501(c)(3) | 2015 | $4 million | $7.6 million | 2025-12 |
| Greater Greenville Chamber of Commerce | 501(c)(6) | 1942 | $3.9 million | $5.6 million | 2024-12 | |
| Greenville Symphony Association | Arts, culture and humanities | 501(c)(3) | 1963 | $3.6 million | $2.6 million | 2025-05 |
| United Ministries | Religion-related | 501(c)(3) | 1975 | $3.6 million | $3.3 million | 2025-06 |
| University Center of Greenville Inc | Education | 501(c)(3) | 2010 | $3.5 million | $3.9 million | 2025-06 |
| Center for Developmental Services D-B-A CDS | Human services | 501(c)(3) | 1994 | $3.5 million | $3.2 million | 2025-12 |
| Safe Harbor Inc | Human services | 501(c)(3) | 1995 | $3.4 million | $18.2 million | 2025-09 |
| Pendleton Place Inc | Human services | 501(c)(3) | 1975 | $3.4 million | $4 million | 2025-06 |
| Upstate South Carolina Alliance Inc | Community improvement and capacity building | 501(c)(6) | 2000 | $3.2 million | $3.5 million | 2024-12 |
| East Link Academy | Education | 501(c)(3) | 2018 | $3.2 million | $1.1 million | 2025-06 |
| Ncees Foundation | Science and technology | 501(c)(3) | 2025 | $3.2 million | $11.8 million | 2025-09 |
| Veritas Preparatory School Inc | Education | 501(c)(3) | 2014 | $3 million | $1.4 million | 2025-06 |
| Upstate Warrior Solution Inc | Human services | 501(c)(3) | 2013 | $3 million | $2 million | 2025-09 |
| Fall for Greenville Inc | Recreation and sports | 501(c)(3) | 1993 | $3 million | $1.1 million | 2025-12 |
| Arrhythmia Technologies Institute | 501(c)(3) | 1989 | $2.9 million | $5.1 million | 2025-08 | |
| South Carolina Charities Inc | Recreation and sports | 501(c)(3) | 2001 | $2.9 million | $849,595 | 2025-06 |
| Metropolitan Arts Council | 501(c)(3) | 1973 | $2.7 million | $6.3 million | 2025-12 | |
| A Childs Haven Inc | 501(c)(3) | 1990 | $2.7 million | $5.8 million | 2025-06 | |
| Together Women Rise | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2004 | $2.7 million | $1.8 million | 2025-12 |
| Cliffs Valley Community Association Inc | Housing and shelter | 501(c)(4) | 2004 | $2.7 million | $4.8 million | 2025-12 |
| Rebuild Upstate | Religion-related | 501(c)(3) | 2007 | $2.6 million | $1.7 million | 2025-08 |
| Faces and Voices of Recovery Greenville | 501(c)(3) | 2012 | $2.6 million | $2.3 million | 2025-06 | |
| Greenville Area Development Corporation | Community improvement and capacity building | 501(c)(3) | 2002 | $2.5 million | $4 million | 2025-06 |
| Boy Scouts of America | 501(c)(3) | 1965 | $2.5 million | $4.3 million | 2025-12 | |
| Greenville Re-Development Coproration | Housing and shelter | 501(c)(3) | 2015 | $2.5 million | $16.1 million | 2024-12 |
| Spinks Family Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2016 | $2.5 million | $8.9 million | 2024-12 |
| National Christian College Athletic Association | Education | 501(c)(3) | 1985 | $2.5 million | $3.5 million | 2025-12 |
| Turning Point of South Carolina Inc | Housing and shelter | 501(c)(3) | 2004 | $2.4 million | $3.2 million | 2025-12 |
| Livewell Greenville | Youth development | 501(c)(3) | 2016 | $2.4 million | $776,300 | 2024-12 |
| SC Vocations & Individual Advancement | Employment | 501(c)(3) | 2010 | $2.4 million | $4.5 million | 2025-06 |
| Neighborhood Cancer Connection | 501(c)(3) | 1966 | $2.3 million | $9.1 million | 2024-12 | |
| Mental Health Association of Greenville County | Mental health and crisis intervention | 501(c)(3) | 1992 | $2.2 million | $4.9 million | 2024-12 |
| Center for Courage & Renewal | Education | 501(c)(3) | 2003 | $2.2 million | $2.6 million | 2025-06 |
| Gateway House Inc | Mental health and crisis intervention | 501(c)(3) | 1984 | $2.2 million | $8.7 million | 2025-12 |
| Evangelical Institute of Greenville S C Inc | 501(c)(3) | 1967 | $2.1 million | $1.3 million | 2025-12 | |
| Southeast Affordable Housing Administration | Housing and shelter | 501(c)(3) | 2022 | $2 million | $275,298 | 2024-12 |
| Senior Action Inc | Human services | 501(c)(3) | 1968 | $2 million | $7.5 million | 2025-06 |
| The Julie Valentine Center | 501(c)(3) | 1977 | $2 million | $794,646 | 2025-06 | |
| Greenville Arts Festival | Arts, culture and humanities | 501(c)(3) | 2004 | $1.9 million | $889,449 | 2025-09 |
| Soteria World Outreach Ministries Inc | Crime and legal-related | 501(c)(3) | 2002 | $1.9 million | $4.2 million | 2024-12 |
| Piedmont Womens Center | Human services | 501(c)(3) | 1992 | $1.9 million | $6.9 million | 2024-12 |
| South Carolina Governors School for the Arts and Humanities Foundation | 501(c)(3) | 1985 | $1.9 million | $9.4 million | 2025-06 | |
| Greenville Family Partnership | Human services | 501(c)(3) | 1984 | $1.9 million | $658,930 | 2024-12 |
| Unity Health On Main | Health care | 501(c)(3) | 2016 | $1.9 million | $634,423 | 2024-12 |
| Greenville Theatre | Arts, culture and humanities | 501(c)(3) | 1949 | $1.8 million | $1.3 million | 2024-06 |
| Greenville Chamber Foundation Inc | 501(c)(3) | 1971 | $1.8 million | $1.4 million | 2024-12 | |
| Furman University Foundation Inc | Education | 501(c)(3) | 2016 | $1.8 million | $22.9 million | 2025-06 |
| Greater Greenville Association of Realtors Inc | 501(c)(6) | 1945 | $1.8 million | $10.2 million | 2024-12 | |
| International Transportation Innovation Center | Community improvement and capacity building | 501(c)(3) | 2011 | $1.8 million | $12.7 million | 2025-09 |
| Carolina Family Services Inc | Human services | 501(c)(3) | 2007 | $1.7 million | $456,162 | 2024-12 |
| Zion World Wide Mission Inc | Religion-related | 501(c)(3) | 2007 | $1.7 million | $1.7 million | 2023-12 |
| Friends of the Greenville Zoo Inc | Animal-related | 501(c)(3) | 1979 | $1.7 million | $3 million | 2025-06 |
| First Presbyterian Church Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1997 | $1.6 million | $5.2 million | 2024-12 |
| South Carolina Childrens Theatre | Arts, culture and humanities | 501(c)(3) | 1988 | $1.6 million | $13.6 million | 2025-08 |
| Jasmine Road Inc | Crime and legal-related | 501(c)(3) | 2017 | $1.6 million | $1.6 million | 2025-07 |
| Chandler School | Education | 501(c)(3) | 2020 | $1.5 million | $3 million | 2025-06 |
| Capita Social Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2018 | $1.4 million | $342,190 | 2025-12 |
| Association of International Metallizers Coaters & Laminators | 501(c)(6) | 1971 | $1.4 million | $2 million | 2025-12 | |
| Triune Mercy Center | Food, agriculture and nutrition | 501(c)(3) | 2004 | $1.4 million | $3.7 million | 2024-12 |
| Ronald McDonald House Charities of the Carolinas Inc | 501(c)(3) | 1987 | $1.4 million | $8.3 million | 2024-12 | |
| Pak7 Us Inc | Religion-related | 501(c)(3) | 2019 | $1.4 million | $447,850 | 2025-12 |
| Upstate Circle of Friends | Human services | 501(c)(3) | 2012 | $1.3 million | $1 million | 2024-12 |
| Project Host Inc | 501(c)(3) | 1993 | $1.3 million | $3.5 million | 2024-12 | |
| Team Greenville Swim Club | Recreation and sports | 501(c)(3) | 1995 | $1.3 million | $693,132 | 2025-08 |
| Islamic Society of Greenville SC | 501(c)(3) | 1989 | $1.3 million | $3.2 million | 2025-12 | |
| Upstate Area Health Education Center | Health care | 501(c)(3) | 1978 | $1.3 million | $2.4 million | 2025-06 |
| Hejaz Shriners | 501(c)(10) | 1940 | $1.3 million | $10.6 million | 2024-12 | |
| Conference Carolinas | Recreation and sports | 501(c)(3) | 1996 | $1.2 million | $582,822 | 2026-06 |
| Multimedia Theological Training | Religion-related | 501(c)(3) | 2022 | $1.2 million | $37,846 | 2025-12 |
| Home Builders Association of Greenville SC Inc | 501(c)(6) | 1991 | $1.2 million | $416,553 | 2024-12 | |
| Lead Collective Inc | Youth development | 501(c)(3) | 2009 | $1.2 million | $1.1 million | 2025-09 |
| Christian Leadership Alliance | 501(c)(3) | 1981 | $1.2 million | $542,098 | 2025-06 | |
| Genesis Homes Inc | Housing and shelter | 501(c)(3) | 2007 | $1.2 million | $14.5 million | 2024-12 |
| Cancer Survivors Park Alliance | Health care | 501(c)(3) | 2000 | $1.2 million | $899,052 | 2025-06 |
| Upstate Father Hood Coalition | Education | 501(c)(3) | 2004 | $1.2 million | $1.3 million | 2025-09 |
| Trees Greenville Inc | Environment | 501(c)(3) | 2005 | $1.2 million | $662,222 | 2025-12 |
| Centre Stage South Carolina | Arts, culture and humanities | 501(c)(3) | 2010 | $1.2 million | $2.8 million | 2025-08 |
| Friends of Cleveland Park Inc | Environment | 501(c)(3) | 2023 | $1.1 million | $10,844 | 2024-12 |
| The Hawkins Foundation | Medical research | 501(c)(3) | 2009 | $1.1 million | $932,446 | 2025-12 |
| Croft House Inc | 501(c)(3) | 1977 | $1.1 million | $767,945 | 2025-09 | |
| Peru Mission USA Inc | Education | 501(c)(3) | 2004 | $1.1 million | $550,105 | 2025-09 |
| Upcountry History Museum | Arts, culture and humanities | 501(c)(3) | 1987 | $1.1 million | $883,056 | 2025-06 |
| Furman Youth Association Inc | Recreation and sports | 501(c)(3) | 2000 | $1.1 million | $85,993 | 2025-04 |
| South Carolina Football Hall of Fame Inc | Recreation and sports | 501(c)(3) | 2014 | $1.1 million | $933,091 | 2024-12 |
| Catapult Labs | Religion-related | 501(c)(3) | 2019 | $1.1 million | $351,208 | 2024-12 |
| CP Now | Education | 501(c)(3) | 2015 | $1.1 million | $746,525 | 2024-12 |
| Carolina International Preparatory School | Education | 501(c)(3) | 2011 | $1 million | $1.6 million | 2025-06 |
| Michelin Charity Golf Tournament | Recreation and sports | 501(c)(3) | 2016 | $1 million | $157,563 | 2025-12 |
| South Carolina Aggregates Association | Community improvement and capacity building | 501(c)(6) | 2020 | $1 million | $770,386 | 2025-06 |
| Legacy Mission International | Religion-related | 501(c)(3) | 2019 | $1 million | $96,222 | 2024-12 |
| Baptist Courier | Religion-related | 501(c)(3) | 1964 | $1 million | $4.8 million | 2024-12 |
| Kings Classical School | Education | 501(c)(3) | 2025 | $1 million | $961,091 | 2025-06 |
| Alianza Hispana-Hispanic Alliance | Human services | 501(c)(3) | 2010 | $991,064 | $375,823 | 2024-12 |
| Partners in Agriculture Inc | Human services | 501(c)(3) | 2014 | $978,617 | $207,744 | 2025-09 |
| The Warehouse Theatre | Arts, culture and humanities | 501(c)(3) | 1975 | $973,589 | $2.8 million | 2025-06 |
| Fostering Great Ideas | Human services | 501(c)(3) | 2011 | $934,367 | $956,760 | 2024-12 |
| Loaves & Fishes | Food, agriculture and nutrition | 501(c)(3) | 1991 | $920,275 | $1.6 million | 2025-12 |
| Greenville Literacy Association Inc | Education | 501(c)(3) | 1974 | $913,934 | $1.7 million | 2025-06 |
| Appalachian Development Corporation | 501(c)(4) | 1982 | $905,097 | $8.4 million | 2025-09 | |
| Service Dogs for Veterans | Public and societal benefit | 501(c)(3) | 2015 | $898,134 | $1.2 million | 2025-12 |
| Scbio Association Health Plan Trust | Mutual and membership benefit | 501(c)(9) | 2025 | $893,405 | $18,463 | 2025-12 |
| Discover Upcountry Carolina Association of South Carolina | Community improvement and capacity building | 501(c)(6) | 2006 | $881,773 | $131,634 | 2025-06 |
| Junior League of Greenville Inc | Community improvement and capacity building | 501(c)(3) | 1949 | $868,579 | $2.2 million | 2026-05 |
| Advanced Institute for Development and Learning | Diseases, disorders and medical disciplines | 501(c)(3) | 2015 | $857,667 | $87,817 | 2023-12 |
| Neighborhood Focus | Human services | 501(c)(3) | 2006 | $851,746 | $905,662 | 2024-12 |
| Allen Temple Community Economic Development Corporation | Community improvement and capacity building | 501(c)(3) | 2005 | $850,244 | $7.3 million | 2025-06 |
| Greenville Connects | Public and societal benefit | 501(c)(3) | 2024 | $841,565 | $522,435 | 2025-12 |
| Abundance Capital | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2021 | $836,532 | $2.3 million | 2024-12 |
| Upstate Emergency Medical Services Council Inc | 501(c)(3) | 1977 | $792,778 | $1.3 million | 2025-06 | |
| Public Education Partners | Education | 501(c)(3) | 1985 | $781,387 | $1.6 million | 2025-06 |
| Museum & Gallery Inc | Arts, culture and humanities | 501(c)(3) | 1992 | $758,539 | $6.5 million | 2025-05 |
| Upstate Greenways and Trails Alliance | Environment | 501(c)(3) | 2020 | $757,463 | $4.2 million | 2024-12 |
| Project Care Inc | Housing and shelter | 501(c)(3) | 1994 | $757,240 | $1.1 million | 2025-09 |
| Poe Mill Achievement Center | Education | 501(c)(3) | 2018 | $744,901 | $978,867 | 2025-12 |
| Cces Endowment Corporation | Diseases, disorders and medical disciplines | 501(c)(3) | 2003 | $741,534 | $8.8 million | 2025-06 |
| BC Corp | Education | 501(c)(3) | 2019 | $740,538 | $86,568 | 2024-12 |
| Local Boys Do Good | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2006 | $732,509 | $1.2 million | 2025-12 |
| G A Properties Inc | 501(c)(3) | 1983 | $703,839 | $2.1 million | 2025-06 | |
| Shared Services Alliance | Mental health and crisis intervention | 501(c)(3) | 2017 | $703,364 | $272,232 | 2025-12 |
| Center for Faithwalk Leadership | Public and societal benefit | 501(c)(3) | 1999 | $694,017 | $651,233 | 2025-06 |
| Upper State Apartment Association Inc | 501(c)(6) | 1987 | $685,221 | $909,905 | 2024-12 | |
| Compass of Carolina Inc | Education | 501(c)(3) | 1964 | $684,418 | $3.8 million | 2024-12 |
| Let There Be Mom Inc | Human services | 501(c)(3) | 2007 | $670,929 | $1.1 million | 2025-12 |
| Greenville Symphony Endowment Fund Inc | Arts, culture and humanities | 501(c)(3) | 2001 | $662,971 | $13.1 million | 2025-05 |
| Medicinal Whiskey Charity Inc | Health care | 501(c)(3) | 2021 | $659,747 | $145,552 | 2024-12 |
| Mena Leadership Center | Religion-related | 501(c)(3) | 2020 | $641,672 | $288,681 | 2025-12 |
| Bel-Aire Community Partners | Education | 501(c)(3) | 2020 | $641,036 | $560,569 | 2025-12 |
| Recraft Creative Reuse Center | Environment | 501(c)(3) | 2019 | $628,840 | $187,212 | 2025-12 |
| Upstate Mediation Center | Crime and legal-related | 501(c)(3) | 2000 | $627,113 | $338,518 | 2025-12 |
| Greenville Local Development Corporation | 501(c)(4) | 1980 | $613,112 | $9 million | 2025-06 | |
| McDowell Housing Corporation | Housing and shelter | 501(c)(3) | 1980 | $611,186 | $1.1 million | 2024-12 |
| Legacy Advancement | Education | 501(c)(3) | 2015 | $608,039 | $2.5 million | 2024-12 |
| Fuller Normal and Industrial Institute | 501(c)(3) | 1969 | $606,972 | $138,691 | 2025-06 | |
| Gower Estates Pool Inc | 501(c)(7) | 1965 | $603,411 | $1.8 million | 2025-03 | |
| Girlup GVL | Youth development | 501(c)(3) | 2020 | $603,125 | $565,762 | 2025-07 |
| Greater Good Greenville | Community improvement and capacity building | 501(c)(3) | 2024 | $602,433 | $421,165 | 2025-12 |
| Amelia Village Housing Corporation | 501(c)(3) | 1984 | $600,754 | $1.3 million | 2025-12 | |
| Feed & Seed Co | Education | 501(c)(3) | 2016 | $599,669 | $2.3 million | 2024-12 |
| Institute of Biblical Leadership | Religion-related | 501(c)(3) | 1990 | $598,813 | $1.5 million | 2024-12 |
| Phillis Wheatley Association | Human services | 501(c)(3) | 1957 | $594,078 | $3.6 million | 2024-12 |
| Flourish Adoption Ministries Inc | Education | 501(c)(3) | 2017 | $586,153 | $197,375 | 2025-12 |
| Pleasant Valley Connection Inc | Human services | 501(c)(3) | 2002 | $583,772 | $882,715 | 2024-12 |
| Brice-Sanders Foundation | Religion-related | 501(c)(3) | 2022 | $578,723 | $1.1 million | 2024-12 |
| Sigal Music Museum | Arts, culture and humanities | 501(c)(3) | 2017 | $559,344 | $2.1 million | 2024-12 |
| Greenville High Red Raider Sports Booster Club Inc | Education | 501(c)(3) | 2005 | $556,496 | $233,651 | 2025-06 |
| Priester Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1998 | $553,060 | $7.2 million | 2025-12 |
| YMCA of Greenville Foundation Inc | Recreation and sports | 501(c)(3) | 2014 | $546,654 | $2.8 million | 2024-12 |
| Veritas Catholic Information Center | Religion-related | 501(c)(3) | 2022 | $543,845 | $761,930 | 2025-12 |
| Greenville Urban League Seniors House | 501(c)(3) | 1984 | $540,846 | $1.2 million | 2024-12 | |
| Road Runners Club of America | 501(c)(3) | 1976 | $538,538 | $656,723 | 2025-12 | |
| Dream Preparatory Academy Inc | Education | 501(c)(3) | 2023 | $534,731 | $33,758 | 2025-12 |
| Carolina Ballet Theatre Inc | Arts, culture and humanities | 501(c)(3) | 1977 | $532,928 | $65,276 | 2025-06 |
| Greenville Center for Creative Arts | Arts, culture and humanities | 501(c)(3) | 2015 | $525,979 | $2.8 million | 2024-12 |
| Highwood Apartments Inc | Housing and shelter | 501(c)(3) | 1982 | $522,706 | $587,915 | 2026-06 |
| Upstate Youth Development Foundation | Recreation and sports | 501(c)(3) | 2010 | $521,699 | $242,259 | 2025-12 |
| Uws Properties | Community improvement and capacity building | 501(c)(2) | 2022 | $518,303 | $9.6 million | 2025-09 |
| Roper Mountain Science Center Association | 501(c)(3) | 1984 | $517,883 | $1.3 million | 2025-06 | |
| The Museum Association Inc | Arts, culture and humanities | 501(c)(3) | 1976 | $509,637 | $840,830 | 2024-12 |
| Carolina Dance Collaborative | Arts, culture and humanities | 501(c)(3) | 2018 | $508,953 | $197,248 | 2025-12 |
| Langston Foundation Inc | Education | 501(c)(3) | 2009 | $506,995 | $4.2 million | 2025-06 |
| Davids Table Inc | Youth development | 501(c)(3) | 2010 | $504,017 | $287,697 | 2024-12 |
| Uu World of Children | Education | 501(c)(3) | 2007 | $503,903 | $902,048 | 2025-06 |
| Rock International Inc | Religion-related | 501(c)(3) | 2008 | $503,433 | $232,580 | 2025-06 |
| Our Upstate-Sc | Community improvement and capacity building | 501(c)(3) | 2011 | $496,253 | $5,111 | 2025-12 |
| Bleeding Disorders Association of South Carolina | Housing and shelter | 501(c)(3) | 1998 | $484,313 | $527,100 | 2025-12 |
| Auxiliary To Greenville Hospital System | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2018 | $473,101 | $163,472 | 2025-09 |
| Donate Life South Carolina | Health care | 501(c)(3) | 1996 | $461,870 | $315,189 | 2025-12 |
| J L Mann Athletic Booster Club Inc | Education | 501(c)(3) | 1999 | $454,376 | $407,960 | 2025-06 |
| Birthright of Greenville Inc | 501(c)(3) | 1981 | $440,962 | $984,865 | 2025-12 | |
| Time Served | Human services | 501(c)(3) | 2024 | $437,583 | $230,572 | 2025-12 |
| Fine Arts Center Partners | Arts, culture and humanities | 501(c)(3) | 2012 | $436,120 | $239,479 | 2025-06 |
| Touched By Als Inc | Human services | 501(c)(3) | 2022 | $432,489 | $423,815 | 2025-12 |
| Ahepa 242 Inc | Housing and shelter | 501(c)(3) | 2006 | $431,123 | $2.7 million | 2025-06 |
| Triune Mercy Center Endowment Fund | Religion-related | 501(c)(3) | 2014 | $429,032 | $2.3 million | 2024-12 |
| Switch | Human services | 501(c)(3) | 2014 | $420,743 | $177,045 | 2024-12 |
| The Family Effect | Social science | 501(c)(3) | 2002 | $419,068 | $761,769 | 2025-06 |
| All About Change Inc | Human services | 501(c)(3) | 2014 | $418,135 | $56,670 | 2025-12 |
| Upstate-Carolina Adaptive Golf | Human services | 501(c)(3) | 2019 | $410,028 | $187,305 | 2025-12 |
| Defenders for Children | Mental health and crisis intervention | 501(c)(3) | 2010 | $409,893 | $716,160 | 2025-12 |
| National Rural Letter Carriers Association | 501(c)(5) | 1972 | $408,663 | $540,653 | 2026-06 | |
| Youthbase Inc | Youth development | 501(c)(3) | 2006 | $406,970 | $251,457 | 2025-07 |
| Windham House Inc | Housing and shelter | 501(c)(3) | 2001 | $401,457 | $1.7 million | 2026-06 |
| Greenville Woodworkers Guild Incorporated | Education | 501(c)(3) | 2004 | $400,495 | $2.1 million | 2025-08 |
| Stone Lake Community Club Inc | Recreation and sports | 501(c)(7) | 2002 | $398,563 | $521,496 | 2025-12 |
| Life Worth Living Project | Mental health and crisis intervention | 501(c)(3) | 2025 | $397,559 | $375,735 | 2025-12 |
| The Barbara Stone Foundation | Mental health and crisis intervention | 501(c)(3) | 1992 | $397,466 | $821,238 | 2025-06 |
| Sustaining Way | Community improvement and capacity building | 501(c)(3) | 2013 | $396,863 | $178,305 | 2025-12 |
| Carolina Recycling Association | Environment | 501(c)(3) | 1989 | $395,917 | $508,315 | 2025-06 |
| Christian Learning Centers of Greenville County | Education | 501(c)(3) | 1998 | $395,229 | $159,217 | 2024-06 |
| Pedalgogy | Recreation and sports | 501(c)(3) | 2019 | $391,524 | $170,943 | 2024-12 |
| Canterbury Counseling Center A Ministry of Christ Church | Mental health and crisis intervention | 501(c)(3) | 2006 | $372,475 | $387,356 | 2025-12 |
| Sarah Simpson Gossett Home Inc | Housing and shelter | 501(c)(3) | 2012 | $367,950 | $78,425 | 2025-12 |
| Greenville Country Club Scholarship Foundation | Education | 501(c)(3) | 2022 | $366,499 | $600,302 | 2025-12 |
| Homeless Period Project | Human services | 501(c)(3) | 2017 | $360,865 | $128,740 | 2025-12 |
| Leo Santa | Human services | 501(c)(3) | 2022 | $360,687 | $40,288 | 2024-12 |
| Nami Greenville SC | 501(c)(3) | 1986 | $358,311 | $364,788 | 2025-12 | |
| Homes With A Mission | Housing and shelter | 501(c)(3) | 2020 | $358,046 | $1.2 million | 2025-12 |
| Chadsworth Drive Swim Club Inc | Recreation and sports | 501(c)(7) | 2023 | $356,393 | $1.5 million | 2025-12 |
| Speak for Animals | Animal-related | 501(c)(3) | 2004 | $355,958 | $134,696 | 2024-12 |
| SC New Play Festival Inc | Arts, culture and humanities | 501(c)(3) | 2023 | $354,165 | $48,216 | 2025-08 |
| Servants for Sight | Diseases, disorders and medical disciplines | 501(c)(3) | 2010 | $353,090 | $793,966 | 2024-12 |
| Norma Locklear-Pitts Senior Community Inc | Housing and shelter | 501(c)(3) | 2008 | $351,782 | $3.1 million | 2025-09 |
| Friends of Momentum Bike Clubs | Youth development | 501(c)(3) | 2014 | $351,397 | $235,684 | 2025-12 |
| 1826 Network | Religion-related | 501(c)(3) | 2019 | $344,325 | $312,610 | 2021-12 |
| Challenges Inc SC | Mental health and crisis intervention | 501(c)(3) | 2019 | $342,659 | $570,659 | 2025-12 |
| Greenville Area Parkinson Society | Public safety, disaster preparedness and relief | 501(c)(3) | 2010 | $338,756 | $155,306 | 2025-12 |
| Westminister Presbyterian Church Endowment Fund | Religion-related | 501(c)(3) | 1997 | $330,484 | $1.3 million | 2024-12 |
| Greenville County Bar Association Inc | 501(c)(6) | 1994 | $324,612 | $102,737 | 2025-12 | |
| Boost | Human services | 501(c)(3) | 2024 | $322,261 | $108,664 | 2024-12 |
| Greenville Civic Chorale Association | 501(c)(3) | 1984 | $319,905 | $211,992 | 2025-06 | |
| Notus Sports | Recreation and sports | 501(c)(3) | 2013 | $314,001 | $99,401 | 2025-06 |
| Greater Greenville Scottish Games and Highland Festival | Recreation and sports | 501(c)(3) | 2005 | $310,888 | $69,316 | 2026-02 |
| Beach Ball Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2005 | $310,003 | $300,243 | 2024-12 |
| Carolina Youth Symphony | Arts, culture and humanities | 501(c)(3) | 1977 | $294,989 | $733,465 | 2025-06 |
| New Way Global | Human services | 501(c)(3) | 2021 | $294,229 | $191,363 | 2024-12 |
| Pour Out Project | Religion-related | 501(c)(3) | 2025 | $292,254 | $186,027 | 2025-12 |
| SC-QRF | Public and societal benefit | 501(c)(3) | 2022 | $291,592 | $64,723 | 2024-12 |
| Foundation for the Child Victims of the Family Court LLC | Youth development | 501(c)(3) | 2023 | $289,001 | $174,881 | 2025-12 |
| Creekside Housing Corporation | Human services | 501(c)(3) | 2009 | $288,574 | $3.4 million | 2025-09 |
| Phillips-Amick Foundation for Cancer Research | Medical research | 501(c)(3) | 2018 | $285,952 | $46,534 | 2025-12 |
| Beyond Housing | 501(c)(3) | 1990 | $276,564 | $1.3 million | 2024-12 | |
| National Association of Letter Carriers | 501(c)(5) | 1944 | $273,478 | $614,857 | 2025-12 | |
| Greenville County Historical Society Inc | Arts, culture and humanities | 501(c)(3) | 1993 | $272,214 | $281,371 | 2026-03 |
| Chin Baptist Church of Greenville | 501(c)(3) | 1964 | $262,402 | $53,214 | 2025-12 | |
| Bold Leadership Network | Public and societal benefit | 501(c)(3) | 2022 | $260,340 | $109,042 | 2024-12 |
| Little League Baseball Inc | 501(c)(3) | 1967 | $259,747 | $115,024 | 2025-09 | |
| Greenvilles Gift | Human services | 501(c)(3) | 2016 | $259,719 | $189,520 | 2025-12 |
| Carlisle Floyd Centennial | Arts, culture and humanities | 501(c)(3) | 2024 | $258,814 | $255,961 | 2025-12 |
| South Carolina Athletic Administrators Association | Education | 501(c)(4) | 2005 | $258,664 | $274,815 | 2025-12 |
| BGM Inc | Mental health and crisis intervention | 501(c)(3) | 2003 | $255,016 | $1.1 million | 2025-12 |
| Strong Missions Inc | International, foreign affairs and national security | 501(c)(3) | 2015 | $252,275 | $11,028 | 2024-12 |
| Ancient & Accepted Scottish Rite of Free Masonry So Juris USA | 501(c)(10) | 1940 | $251,822 | $7 million | 2025-12 | |
| Center for Global Strategies LTD | International, foreign affairs and national security | 501(c)(3) | 2006 | $246,952 | $231,995 | 2025-12 |
| Ten at the Top | Community improvement and capacity building | 501(c)(4) | 2011 | $244,994 | $5,743 | 2025-12 |
| Harold C Jennings Foundation | Education | 501(c)(3) | 1977 | $244,763 | $1.8 million | 2025-12 |
| Best Skills Academy | Education | 501(c)(3) | 2019 | $244,315 | $180,825 | 2025-12 |
| MC Carter Community Club | Recreation and sports | 501(c)(7) | 2016 | $241,832 | $269,039 | 2025-12 |
| Benevolence at Work Inc | Religion-related | 501(c)(3) | 2026 | $240,500 | $232,000 | 2025-12 |
| 864pride | 501(c)(3) | 2021 | $239,731 | $25,607 | 2025-12 | |
| Our Saviour Community Ministries | Education | 501(c)(3) | 2015 | $236,826 | $314,755 | 2025-06 |
| Botany Woods Country Club Inc | 501(c)(7) | 1967 | $235,948 | $256,192 | 2025-12 | |
| Partner 10 15 Ministries | Religion-related | 501(c)(3) | 2021 | $234,549 | $25,155 | 2024-12 |
| First Impression Inc | Housing and shelter | 501(c)(3) | 2022 | $234,179 | $37,483 | 2024-12 |
| PMP Community Park | 501(c)(7) | 1971 | $233,580 | $461,805 | 2025-10 | |
| Challenge To Conquer Cancer | Medical research | 501(c)(3) | 2006 | $232,762 | $11,145 | 2025-12 |
| Greenville Society for Human Resource Management | Community improvement and capacity building | 501(c)(6) | 2014 | $230,640 | $247,715 | 2025-12 |
| Mountain View Christian Counseling | Human services | 501(c)(3) | 2022 | $230,146 | $29,409 | 2025-12 |
| Omkar Hindu Society | Religion-related | 501(c)(3) | 2024 | $229,456 | $5,570 | 2025-12 |
| India Association of Greenville Inc | Arts, culture and humanities | 501(c)(3) | 2017 | $225,473 | $207,479 | 2025-12 |
| Duke Ministry for Christ | Religion-related | 501(c)(3) | 1980 | $219,882 | $373,373 | 2026-05 |
| Legacy Affordable Housing Trust | Housing and shelter | 501(c)(3) | 2022 | $219,640 | $304,575 | 2024-12 |
| The Hawkins Society Inc | 501(c)(6) | 2024 | $215,394 | $12,017 | 2025-12 | |
| Lucky Pup Rescue | Animal-related | 501(c)(3) | 2024 | $214,040 | $10,501 | 2023-12 |
| Upstate International | Human services | 501(c)(3) | 1999 | $209,133 | $381,978 | 2024-12 |
| South Carolina Dialogue Foundation | Community improvement and capacity building | 501(c)(3) | 2014 | $208,687 | $2.7 million | 2024-12 |
| American Postal Workers Union | 501(c)(5) | 1973 | $205,933 | $345,663 | 2025-12 | |
| Family Life Center International Inc | Religion-related | 501(c)(3) | 1994 | $202,911 | $2 million | 2024-12 |
| Frazor Evangelistic Association | Religion-related | 501(c)(3) | 2007 | $202,015 | $57,252 | 2024-12 |
| Face To Face Network | Religion-related | 501(c)(3) | 2013 | $199,865 | $68,494 | 2025-12 |
| Charis Language Immersion Academy | Education | 501(c)(3) | 2023 | $199,376 | $47,613 | 2025-12 |
| Infinite Possibilities Inc | Youth development | 501(c)(3) | 2021 | $193,858 | $7,915 | 2025-12 |
| Japan America Association of Western SC Inc | International, foreign affairs and national security | 501(c)(3) | 1990 | $193,821 | $163,876 | 2026-03 |
| Hejaz Shriners Group Return | 501(c)(10) | 1940 | $193,601 | $708,133 | 2024-12 | |
| Feed Our Neighbors Food Pantry | Food, agriculture and nutrition | 501(c)(3) | 2025 | $193,038 | $112,061 | 2026-06 |
| Clover Commons Inc | Human services | 501(c)(3) | 1999 | $192,084 | $741,247 | 2025-06 |
| Lead Upstate Inc | 501(c)(3) | 2020 | $191,255 | $149,399 | 2026-04 | |
| Knights of Columbus | 501(c)(8) | 1940 | $191,207 | $119,840 | 2025-06 | |
| Dog Squad | Animal-related | 501(c)(3) | 2022 | $191,186 | $53,391 | 2024-12 |
| Guardians of Greenville County | Civil rights, social action and advocacy | 501(c)(4) | 2025 | $186,149 | $1,638 | 2024-12 |
| The Sisk Foundation of Buncombe Street United Methodist Church | 501(c)(3) | 1986 | $181,758 | $7.3 million | 2025-12 | |
| Grace Harbor Ministries Inc | Environment | 501(c)(3) | 1995 | $181,301 | $418,405 | 2025-12 |
| Holly Way Elderly Housing Inc | Housing and shelter | 501(c)(3) | 2000 | $181,111 | $757,020 | 2026-03 |
| Safety Components First Responder 911 Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2003 | $181,052 | $29,057 | 2024-12 |
| Crossroads Career Services Inc | Employment | 501(c)(3) | 2002 | $180,919 | $101,785 | 2025-12 |
| American Legion | 501(c)(19) | 1946 | $178,472 | $2 million | 2025-06 | |
| Carolina Loving Hound Rescue | Animal-related | 501(c)(3) | 2018 | $176,248 | $74,383 | 2024-12 |
| South Carolinians for Alternatives To the Death Penalty | Civil rights, social action and advocacy | 501(c)(3) | 2010 | $175,558 | $189,012 | 2025-12 |
| Greenville County Youth Orchestra Association Inc | 501(c)(3) | 1986 | $174,772 | $132,572 | 2025-06 | |
| Partners in Animal Care Inc | Animal-related | 501(c)(3) | 2016 | $174,152 | $360,092 | 2025-06 |
| Sunset Village | Human services | 501(c)(3) | 2007 | $171,423 | $1.6 million | 2025-09 |
| Goal-Justice | Civil rights, social action and advocacy | 501(c)(3) | 2022 | $171,255 | $96,081 | 2025-12 |
| Nicholtown Child and Family Collaborative | Human services | 501(c)(3) | 2017 | $171,081 | $128,013 | 2025-12 |
| Hands of Kindness Childrens Ministry | International, foreign affairs and national security | 501(c)(3) | 2020 | $169,724 | $26,711 | 2025-12 |
| MTT Ministries | Religion-related | 501(c)(3) | 2002 | $169,341 | $73,906 | 2024-12 |
| Cancer Crackdown Inc | Human services | 501(c)(3) | 2014 | $169,049 | $89,414 | 2024-12 |
| The Portals Inc | 501(c)(3) | 1987 | $168,999 | $424,973 | 2025-03 | |
| Makers Collective | Community improvement and capacity building | 501(c)(4) | 2011 | $168,895 | $115,100 | 2025-12 |
| Sickle Forward | Health care | 501(c)(3) | 2023 | $168,023 | $235,014 | 2025-12 |
| KB Charitable Trust | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2001 | $167,191 | $231,077 | 2025-12 |
| Mosaic Educational and Arts Program | Youth development | 501(c)(3) | 2018 | $166,379 | $54,500 | 2025-12 |
| Gospel Reformation Network | Religion-related | 501(c)(3) | 2017 | $166,324 | $92,289 | 2024-12 |
| Embrace the Dream Foundation Inc | Human services | 501(c)(3) | 2013 | $166,157 | $89,431 | 2025-12 |
| Morgan Lane Housing Inc | Housing and shelter | 501(c)(3) | 2005 | $163,550 | $892,947 | 2026-06 |
| Kind of the Upstate | Education | 501(c)(3) | 2021 | $163,435 | $143,929 | 2025-12 |
| Shriners International | 501(c)(10) | 1940 | $162,964 | $101,825 | 2024-12 | |
| National Concrete Burial Vault Association Inc | 501(c)(6) | 1959 | $162,096 | $169,365 | 2025-12 | |
| Greenville Sheriffs Foundation | 501(c)(3) | 1984 | $161,514 | $267,826 | 2024-12 | |
| South Carolina Art Education Association Inc | Arts, culture and humanities | 501(c)(3) | 2023 | $161,059 | $88,005 | 2025-06 |
| Dave Walton Evangelistic Association Inc | Religion-related | 501(c)(3) | 2005 | $160,760 | $10,262 | 2025-12 |
| Friends of Reedy River Inc | Environment | 501(c)(3) | 1994 | $160,600 | $102,003 | 2025-12 |
| Walts Waltz | Mental health and crisis intervention | 501(c)(3) | 2020 | $159,051 | $149,739 | 2025-12 |
| Bike Walk Greenville | Community improvement and capacity building | 501(c)(3) | 2014 | $157,560 | $186,774 | 2024-12 |
| Drayton Village Inc | Housing and shelter | 501(c)(3) | 2004 | $157,323 | $690,551 | 2025-06 |
| Unidiversity Youth Camp Inc | Arts, culture and humanities | 501(c)(3) | 2018 | $156,796 | $171,230 | 2025-12 |
| Roots and Wings Nature School | Education | 501(c)(3) | 2024 | $156,374 | $40,382 | 2025-12 |
| Crew Upstate South Carolina | Community improvement and capacity building | 501(c)(6) | 2010 | $156,184 | $158,036 | 2025-12 |
| Greenville Chautauqua Society | Arts, culture and humanities | 501(c)(3) | 2003 | $156,128 | $152,624 | 2025-08 |
| Cypress Park Apartments Inc | Housing and shelter | 501(c)(3) | 2008 | $154,678 | $1.2 million | 2025-09 |
| Alice House | Housing and shelter | 501(c)(3) | 2025 | $153,933 | $107,849 | 2025-12 |
| Urban League of the Upstate Senior Housing Corporation | Housing and shelter | 501(c)(3) | 1999 | $152,532 | $695,246 | 2024-12 |
| Saint Andrews Society of Upper South Carolina | Arts, culture and humanities | 501(c)(7) | 2003 | $152,376 | $39,765 | 2025-12 |
| Holly Way II Inc | Housing and shelter | 501(c)(3) | 2008 | $149,502 | $922,698 | 2026-03 |
| Lancaster Landing Inc | Mental health and crisis intervention | 501(c)(3) | 2003 | $148,619 | $736,938 | 2025-06 |
| Boy Scouts of America | 501(c)(3) | 1965 | $147,628 | $3.2 million | 2025-12 | |
| Draymont Housing Corporation | Housing and shelter | 501(c)(3) | 2004 | $147,001 | $606,837 | 2025-09 |
| Pta South Carolina Congress | 501(c)(3) | 1979 | $146,397 | $183,871 | 2025-06 | |
| Mental Health Association of Greenville County Housing | Housing and shelter | 501(c)(3) | 2025 | $145,178 | $955,081 | 2020-06 |
| Fresh Start SC | Community improvement and capacity building | 501(c)(3) | 2011 | $143,175 | $130,304 | 2025-12 |
| Shriners International | 501(c)(10) | 1940 | $142,794 | $455,273 | 2024-12 | |
| Everything Outdoor Fest | Community improvement and capacity building | 501(c)(3) | 2024 | $141,788 | $38,414 | 2025-12 |
| Reconciliation Ministries Inc | Religion-related | 501(c)(3) | 1991 | $136,315 | $45,035 | 2025-12 |
| Judson Community Partnership | Human services | 501(c)(3) | 2015 | $136,115 | $122,111 | 2025-12 |
| Safety On Site | Public safety, disaster preparedness and relief | 501(c)(3) | 2023 | $134,991 | $47,349 | 2024-12 |
| Foothills Trail Conference Inc | 501(c)(3) | 1981 | $132,587 | $998,832 | 2025-12 | |
| Capps Villa Inc | Housing and shelter | 501(c)(3) | 2007 | $132,575 | $1.1 million | 2025-09 |
| Country Gardens Inc | Housing and shelter | 501(c)(3) | 2009 | $131,684 | $1.3 million | 2025-09 |
| South Carolina Association of Neurological Surgeons Inc | Health care | 501(c)(3) | 2024 | $131,151 | $343,746 | 2025-12 |
| River Upstate | Public and societal benefit | 501(c)(3) | 2019 | $130,662 | $21,192 | 2025-06 |
| New Prospects Housing Corporation | Housing and shelter | 501(c)(3) | 2003 | $130,651 | $772,622 | 2025-09 |
| Coles Victory Lap | Health care | 501(c)(3) | 2022 | $129,324 | $567,390 | 2024-12 |
| Church Works Media Inc | 501(c)(3) | 2018 | $128,303 | $17,244 | 2024-12 | |
| Christian Collectivity To Reach Others Needs Inc | International, foreign affairs and national security | 501(c)(3) | 2011 | $128,074 | $53,615 | 2025-12 |
| Savita Institute | Health care | 501(c)(3) | 2023 | $128,000 | $433,340 | 2024-12 |
| Davis Lar International Childrens Fund Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2012 | $127,264 | $36,438 | 2025-12 |
| Benevolent & Protective Order of Elks of the USA | 501(c)(8) | 1951 | $125,448 | $366,739 | 2026-03 | |
| Brookhaven Housing Corporation | Housing and shelter | 501(c)(3) | 2003 | $125,269 | $461,543 | 2025-09 |
| South Carolina Association of Opticians | 501(c)(6) | 1980 | $124,882 | $575,382 | 2025-12 | |
| Pta South Carolina Congress | 501(c)(3) | 1979 | $123,919 | $271,926 | 2025-06 | |
| Pi Kappa Phi Fraternity | 501(c)(7) | 1941 | $123,828 | $24,212 | 2025-06 | |
| Ayres Housing Inc | Human services | 501(c)(3) | 1993 | $122,619 | $377,977 | 2025-06 |
| South Carolina Congress of Parents and Teachers | 501(c)(3) | 1979 | $122,606 | $136,170 | 2026-06 | |
| Rotary International | 501(c)(4) | 1942 | $121,818 | $171,273 | 2026-06 | |
| Poinsett Club Foundation | Arts, culture and humanities | 501(c)(3) | 2010 | $121,260 | $434,751 | 2024-12 |
| Greenville Jewish Federation Inc | 501(c)(3) | 1970 | $119,814 | $97,940 | 2025-12 | |
| Echoes of Emma Inc | Education | 501(c)(3) | 2023 | $117,531 | $120,845 | 2025-12 |
| Christ for Ireland Inc | Religion-related | 501(c)(3) | 2009 | $117,452 | $22,227 | 2025-12 |
| Gods Little Ones Inc | International, foreign affairs and national security | 501(c)(3) | 2007 | $116,483 | $51,814 | 2025-12 |
| Selah Grey Foundation | Human services | 501(c)(3) | 2025 | $115,311 | $13,719 | 2025-12 |
| Chicora Voices | Arts, culture and humanities | 501(c)(3) | 1995 | $114,291 | $49,852 | 2025-06 |
| Half A Sorrow Foundation | Mental health and crisis intervention | 501(c)(3) | 2020 | $113,744 | $51,782 | 2025-12 |
| Powdersville High School Athletic Booster Club Inc | Education | 501(c)(3) | 2011 | $112,674 | $52,331 | 2025-07 |
| Wellington Green Recreation Association | Recreation and sports | 501(c)(7) | 2014 | $112,633 | $102,134 | 2024-12 |
| Greenville County Schools Foundation | Education | 501(c)(3) | 2014 | $112,065 | $181,481 | 2024-12 |
| Furman Future | Youth development | 501(c)(3) | 2022 | $111,910 | $1,444 | 2025-12 |
| Greenville Jazz Collective | Arts, culture and humanities | 501(c)(3) | 2014 | $111,660 | $901 | 2024-12 |
| Elloree Smith Senior Living Inc | Housing and shelter | 501(c)(3) | 2018 | $111,133 | $925,491 | 2026-03 |
| Swim Association Invitational League of Greenville | 501(c)(4) | 1998 | $108,419 | $118,909 | 2025-12 | |
| Glam Fam Booster Club | Recreation and sports | 501(c)(3) | 2025 | $108,216 | $27,665 | 2025-12 |
| Kappa Delta Sorority | 501(c)(7) | 1970 | $107,922 | $32,956 | 2025-06 | |
| Seneca Housing Corporation | Housing and shelter | 501(c)(3) | 2005 | $107,398 | $714,694 | 2025-09 |
| First Responder Benefit Association | Public safety, disaster preparedness and relief | 501(c)(3) | 2018 | $106,963 | $48,787 | 2025-12 |
| Pta South Carolina Congress | 501(c)(3) | 1979 | $105,188 | $52,452 | 2025-06 | |
| Greenville Gay Mens Chorus | Arts, culture and humanities | 501(c)(3) | 2019 | $104,827 | $1 | 2025-12 |
| Clark Nesbitts No Dreams Deferred | Arts, culture and humanities | 501(c)(3) | 2024 | $104,166 | $4,545 | 2025-12 |
| Browning Development Inc | Housing and shelter | 501(c)(3) | 1994 | $103,598 | $277,525 | 2025-06 |
| Applied Theatre Center Inc | Human services | 501(c)(3) | 2019 | $103,100 | $67,055 | 2025-12 |
| South Carolina Coalition for the Homeless | Housing and shelter | 501(c)(3) | 2011 | $102,956 | $13,621 | 2025-12 |
| Buncombe Street Scouting Troop 9 in C | Youth development | 501(c)(3) | 2026 | $101,850 | $24,654 | 2025-08 |
| South Carolina Farm Bureau Association | 501(c)(5) | 1973 | $100,026 | $537,430 | 2024-12 | |
| Luckys Mobility Network | Human services | 501(c)(3) | 2025 | $100,000 | $100,000 | 2025-12 |
| Refuge Sports Inc | Arts, culture and humanities | 501(c)(3) | 2015 | $99,596 | $90,696 | 2025-12 |
| Greater Greenville Master Gardeners | Environment | 501(c)(3) | 2007 | $98,420 | $91,562 | 2025-06 |
| Abundant Grace International | Religion-related | 501(c)(3) | 2013 | $97,834 | $21,059 | 2026-04 |
| JL Mann Band Boosters | Arts, culture and humanities | 501(c)(3) | 2014 | $97,776 | $73,556 | 2025-06 |
| Rivertree Singers | Arts, culture and humanities | 501(c)(3) | 2015 | $97,502 | $31,132 | 2025-06 |
| Foothills Golden Retriver Rescue Inc | Animal-related | 501(c)(3) | 2001 | $96,334 | $213,737 | 2025-12 |
| World Upside Down SC | Arts, culture and humanities | 501(c)(3) | 2024 | $95,632 | $4,606 | 2025-12 |
| Christian Literature Advance | Arts, culture and humanities | 501(c)(3) | 1965 | $94,672 | $18,389 | 2025-12 |
| Pta South Carolina Congress | 501(c)(3) | 1979 | $94,582 | $116,003 | 2025-06 | |
| Spinx Teammate Assistance Fund | Mutual and membership benefit | 501(c)(3) | 2017 | $94,029 | $359,749 | 2024-12 |
| Pet Haven of South Carolina | Animal-related | 501(c)(3) | 2008 | $93,246 | $18,186 | 2025-12 |
| Stone Development Inc | Human services | 501(c)(3) | 1992 | $93,135 | $231,717 | 2025-06 |
| South Carolina Ovarian Cancer Foundation | Diseases, disorders and medical disciplines | 501(c)(3) | 2000 | $91,726 | $460,301 | 2024-12 |
| Otts Branch Elderly Housing Inc | Housing and shelter | 501(c)(3) | 2009 | $90,330 | $866,940 | 2026-03 |
| Systematic Tutoring Resulting in Development of Essential Skills | Education | 501(c)(3) | 2005 | $90,082 | $49,542 | 2025-12 |
| Ipock Inc | Housing and shelter | 501(c)(3) | 2006 | $89,799 | $643,169 | 2025-06 |
| Shriners International | 501(c)(10) | 1940 | $88,925 | $274,008 | 2024-12 | |
| Parent Booster USA Inc | Education | 501(c)(3) | 2005 | $88,138 | $14,709 | 2026-05 |
| Mavericks Touchdown Club | Recreation and sports | 501(c)(3) | 2018 | $86,848 | $38,206 | 2025-12 |
| Prisma Health Ltach - Baptist | Health care | 501(c)(3) | 2026 | $86,779 | $1.6 million | 2025-09 |
| SC State Head Start Association | Human services | 501(c)(3) | 2023 | $86,627 | $1 | 2024-03 |
| Bright Spot Hour Inc | Religion-related | 501(c)(3) | 1998 | $85,028 | $106,731 | 2025-12 |
| Greenville Concert Band | 501(c)(3) | 1982 | $84,541 | $94,336 | 2025-12 | |
| Greenville Council of Garden Clubs Inc | Environment | 501(c)(3) | 1975 | $83,652 | $452,833 | 2025-08 |
| Caesars Head Water Company Inc | 501(c)(12) | 1986 | $82,758 | $167,582 | 2025-09 | |
| Pool at Hollingsworth Park Swim Team | Recreation and sports | 501(c)(3) | 2026 | $82,721 | $19,220 | 2025-12 |
| Arizonas Childrens Charities Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2019 | $82,025 | $2,870 | 2025-12 |
| Friends of the Greenville Co Library | 501(c)(3) | 1972 | $81,796 | $200,767 | 2025-06 | |
| Greenville Police Foundation Inc | Crime and legal-related | 501(c)(3) | 2016 | $81,314 | $78,576 | 2025-12 |
| North Greenville Crisis Ministry | Food, agriculture and nutrition | 501(c)(3) | 2003 | $81,222 | $255,304 | 2025-12 |
| Greenville Zoo Educational Foundation Inc | Animal-related | 501(c)(3) | 1997 | $80,997 | $1 million | 2025-06 |
| Communication Workers of America | 501(c)(5) | 1951 | $80,837 | $31,612 | 2025-09 | |
| South Carolina Congress of Parents and Teachers | 501(c)(3) | 1979 | $77,863 | $57,083 | 2026-06 | |
| Compassion United Inc | Public safety, disaster preparedness and relief | 501(c)(3) | 2017 | $76,697 | $2,582 | 2025-12 |
| Greenville Youth Chorale | Arts, culture and humanities | 501(c)(3) | 2020 | $76,606 | $16,625 | 2025-07 |
| Innovision Awards Organization | Science and technology | 501(c)(3) | 2011 | $76,585 | $19,523 | 2025-12 |
| New Mind Health and Care | Crime and legal-related | 501(c)(3) | 2013 | $76,552 | $52,515 | 2024-12 |
| Auxiliary of the Shriners Hospital of Grenville SC | 501(c)(3) | 1971 | $76,511 | $212,999 | 2025-12 | |
| Gateway Apartments Inc | 501(c)(3) | 1992 | $76,258 | $439,258 | 2024-12 | |
| I Am Changed | Human services | 501(c)(3) | 2015 | $75,000 | $37,784 | 2025-12 |
| Period Education Project | 501(c)(3) | 2017 | $73,266 | $44,983 | 2025-12 | |
| La Mesa Del Padre-The Fathers Table | Religion-related | 501(c)(3) | 2014 | $73,250 | $313,699 | 2024-12 |
| Greenville News Holiday Sunshine Fund | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2022 | $72,764 | $45,355 | 2025-12 |
| Solid Grounds Ministries Inc | Youth development | 501(c)(3) | 2007 | $72,160 | $33,925 | 2025-12 |
| Beth Israel Cemetery Association Inc Term | Mutual and membership benefit | 501(c)(13) | 2011 | $72,129 | $1.2 million | 2024-12 |
| Asociacion Hispano Americana de Mujeres | Education | 501(c)(3) | 2000 | $71,853 | $177,369 | 2025-12 |
| Gladiator Sports | Recreation and sports | 501(c)(3) | 2013 | $71,797 | $16,565 | 2025-12 |
| Enoree River Center | Community improvement and capacity building | 501(c)(3) | 2025 | $71,763 | $1 | 2025-12 |
| Boasc Inc | Public and societal benefit | 501(c)(3) | 2024 | $71,390 | $46,123 | 2025-12 |
| Pta South Carolina Congress | 501(c)(3) | 1979 | $69,790 | $97,605 | 2025-06 | |
| Open Door Biblical Counseling Center | Human services | 501(c)(3) | 2020 | $69,183 | $13,412 | 2025-12 |
| Histurn Ministries Inc | Human services | 501(c)(3) | 2010 | $68,669 | $11,414 | 2025-12 |
| Shriners International | 501(c)(10) | 1940 | $68,656 | $390,586 | 2024-12 | |
| Shriners International | 501(c)(10) | 1940 | $67,752 | $471,636 | 2024-12 | |
| Hillcrest Heights Inc | Housing and shelter | 501(c)(3) | 2024 | $67,612 | $255,235 | 2021-12 |
| Living Bread Inc | Health care | 501(c)(3) | 2013 | $66,765 | $9,810 | 2025-12 |
| The Assembly | 501(c)(7) | $64,734 | $108,338 | 2026-02 | ||
| Upper Piedmont Tennis Association- Women | Recreation and sports | 501(c)(7) | 2007 | $64,536 | $42,905 | 2025-12 |
| Epsilon Tau Omega Endowment Fund Inc | 501(c)(3) | 1992 | $64,298 | $398,284 | 2025-12 | |
| Harvest Edge Corporation | Human services | 501(c)(3) | 2021 | $63,945 | $207,245 | 2025-12 |
| South Carolina Congress of Parents and Teachers | 501(c)(3) | 1979 | $63,929 | $77,707 | 2025-06 |
By cause in Greenville, SC
- Religion-related 190
- Education 167
- Human services 144
- Philanthropy, voluntarism and grantmaking foundations 95
- Arts, culture and humanities 91
- Community improvement and capacity building 68
- Recreation and sports 61
- Housing and shelter 59
- Health care 44
- Youth development 41
- Mental health and crisis intervention 27
- Animal-related 27
- Public and societal benefit 27
- Environment 22
- Civil rights, social action and advocacy 15
- Crime and legal-related 14
- International, foreign affairs and national security 13
- Food, agriculture and nutrition 11
- Public safety, disaster preparedness and relief 11
- Employment 10
- Diseases, disorders and medical disciplines 8
- Mutual and membership benefit 8
- Science and technology 6
- Medical research 5
- Social science 3
Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.