Data / Nonprofits / South Carolina / Greenville / Health care
Health care nonprofits in Greenville, SC: 44 registered with the IRS
44 health care nonprofits are registered with the IRS in Greenville, SC, 44 of them 501(c)(3) charities; the 24 that report revenue took in $7.67 billion. The largest by revenue: Prisma Health - Upstate ($3.61 billion), Prisma Health-Midlands ($2.08 billion), Prisma Health-University Medical Group ($925.8 million).
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Every organization, largest by revenue first
| Organization | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|
| Prisma Health - Upstate | 501(c)(3) | 2016 | $3.61 billion | $1.41 billion | 2025-09 |
| Prisma Health-Midlands | 501(c)(3) | 1997 | $2.08 billion | $1.06 billion | 2025-09 |
| Prisma Health-University Medical Group | 501(c)(3) | 1998 | $925.8 million | $132.7 million | 2025-09 |
| Prisma Health | 501(c)(3) | 2017 | $339.5 million | $4.64 billion | 2025-09 |
| Prisma Health - Blount Memorial Hospital Inc | 501(c)(3) | 2025 | $240.5 million | $166.6 million | 2025-09 |
| Greenville Health Corporation | 501(c)(3) | 1999 | $230.3 million | $66.7 million | 2025-09 |
| Bon Secours Medical Group Greenville Specialty Care LLC | 501(c)(3) | 2023 | $155.6 million | $24.4 million | 2024-12 |
| St Francis Physician Services Inc | 501(c)(3) | 2006 | $36.9 million | $123.7 million | 2024-12 |
| New Horizon Family Health Services Inc | 501(c)(3) | 1991 | $31.3 million | $23.3 million | 2025-01 |
| Blount Memorial Physician Group Inc | 501(c)(3) | 2026 | $15.6 million | $20.1 million | 2025-09 |
| Make-A-Wish Foundation of SC Inc | 501(c)(3) | 1985 | $5.1 million | $4.3 million | 2025-08 |
| Unity Health On Main | 501(c)(3) | 2016 | $1.9 million | $634,423 | 2024-12 |
| Upstate Area Health Education Center | 501(c)(3) | 1978 | $1.3 million | $2.4 million | 2025-06 |
| Cancer Survivors Park Alliance | 501(c)(3) | 2000 | $1.2 million | $899,052 | 2025-06 |
| Medicinal Whiskey Charity Inc | 501(c)(3) | 2021 | $659,747 | $145,552 | 2024-12 |
| Donate Life South Carolina | 501(c)(3) | 1996 | $461,870 | $315,189 | 2025-12 |
| Sickle Forward | 501(c)(3) | 2023 | $168,023 | $235,014 | 2025-12 |
| South Carolina Association of Neurological Surgeons Inc | 501(c)(3) | 2024 | $131,151 | $343,746 | 2025-12 |
| Coles Victory Lap | 501(c)(3) | 2022 | $129,324 | $567,390 | 2024-12 |
| Savita Institute | 501(c)(3) | 2023 | $128,000 | $433,340 | 2024-12 |
| Prisma Health Ltach - Baptist | 501(c)(3) | 2026 | $86,779 | $1.6 million | 2025-09 |
| Living Bread Inc | 501(c)(3) | 2013 | $66,765 | $9,810 | 2025-12 |
| Iron Disorders Institute | 501(c)(3) | 1998 | $8,365 | $28,267 | 2026-06 |
| The 621 Foundation | 501(c)(3) | 2026 | $562 | $506 | 2025-12 |
| Agd- Always Giving Divine | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Association for Professionals in Infection CTRL & Epidemiology Inc | 501(c)(3) | 1975 | $0 | $0 | 2025-12 |
| Buncombe Street Methodist Church Endowment Fund Inc | 501(c)(3) | 2025 | |||
| Caring Bridge | 501(c)(3) | 2022 | $0 | $0 | 2023-12 |
| Divine Trinity House of Hope Inc | 501(c)(3) | 2024 | $0 | $0 | 2020-12 |
| Dr Hope & Health Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Flourish Family Medicine and Obgyn | 501(c)(3) | 2025 | |||
| Governor Robert Daniell Foundation | 501(c)(3) | 2013 | $0 | $0 | 2025-05 |
| Greenville Health Authority | 501(c)(3) | 1944 | 2016-09 | ||
| Healing Endometriosis Research Foundation | 501(c)(3) | 2024 | |||
| Miyinspiration | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Optimal Soul Foundation | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Piedmont Health Foundation | 501(c)(3) | 1992 | $2.7 million | 2025-12 | |
| Prisma Health Eastern Tennessee | 501(c)(3) | 2025 | $0 | $1 | 2025-09 |
| Richland Memorial Hospital | 501(c)(3) | 1959 | 1998-09 | ||
| SGT Zachs Freedom Foundation | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
| Six Nineteen Spirits of 1865 Foundation | 501(c)(3) | 2024 | |||
| The Alice T Oliver Aizheimer Foundation Inc | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Upstate Obesity Alliance | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Velo Valets Gives Back | 501(c)(3) | 2017 | $0 | $0 | 2026-01 |
Other causes in Greenville, SC
- Religion-related 190
- Education 167
- Human services 144
- Philanthropy, voluntarism and grantmaking foundations 95
- Arts, culture and humanities 91
- Community improvement and capacity building 68
- Recreation and sports 61
- Housing and shelter 59
- Youth development 41
- Mental health and crisis intervention 27
- Animal-related 27
- Public and societal benefit 27
- Environment 22
- Civil rights, social action and advocacy 15
- Crime and legal-related 14
- International, foreign affairs and national security 13
- Food, agriculture and nutrition 11
- Public safety, disaster preparedness and relief 11
- Employment 10
- Diseases, disorders and medical disciplines 8
- Mutual and membership benefit 8
- Science and technology 6
- Medical research 5
- Social science 3
Every nonprofit in Greenville, SC · Health care nonprofits across the state · Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.