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Data / Nonprofits / South Carolina / Lancaster

Nonprofits in Lancaster, SC: 261 registered with the IRS

261 nonprofits are registered with the IRS in Lancaster, SC, 232 of them 501(c)(3) charities; the 59 that report revenue took in $35.2 million. The largest by revenue: Chester Lancaster Disabilities & Special Needs Board Inc ($8.6 million), Christian Services Inc ($3 million), Lancaster Childrens Home Inc ($3 million). Most common causes: religion-related (41), human services (30), education (24).

SpecStream is the live web data engine for teams and agents. It reads the IRS register of exempt organizations as the IRS updates it, and this page is that reading. Ask for the nonprofits you need by place, cause and size, with their latest Form 990 figures and websites, and they arrive in your sheet, CRM, Slack or agent.

Every organization, largest by revenue first

OrganizationCategoryTypeSinceRevenueAssetsFiling
Chester Lancaster Disabilities & Special Needs Board IncHuman services501(c)(3)1989$8.6 million$4.3 million2025-06
Christian Services IncHuman services501(c)(3)2005$3 million$625,2772024-12
Lancaster Childrens Home Inc501(c)(3)1962$3 million$4.1 million2025-06
Lancaster County Council On Aging IncHuman services501(c)(3)1976$1.9 million$1.7 million2025-06
Goldencare IncHealth care501(c)(3)2002$1.8 million$2.6 million2024-12
Mid-Carolina Area Health Education Consortium Inc501(c)(3)1977$1.7 million$4 million2025-06
Discovery School of Lancaster CountyEducation501(c)(3)2001$1.7 million$4,2252025-06
The Educational Foundation of the University of South Carolina LancaEducation501(c)(3)1964$1.7 million$20.6 million2025-06
Hope in Lancaster IncHuman services501(c)(3)1983$1.2 million$943,8572024-12
The Fiduciary and Investment Risk Management Association IncCommunity improvement and capacity building501(c)(6)2002$901,174$1.1 million2025-12
Childrens Council501(c)(3)1989$848,029$179,7932024-12
El Rophe Center Inc501(c)(3)1988$650,258$503,0292025-06
A Fathers WayHuman services501(c)(3)2000$638,034$97,0302024-09
Palmetto Citizens Against Sexual Assault501(c)(3)1987$574,977$662,9782025-06
Lancaster SpcaAnimal-related501(c)(3)2014$537,543$266,3062024-12
Lancaster Chamber of CommerceCommunity improvement and capacity building501(c)(6)2024$497,203$635,1092024-12
Lancaster County Society for Historical Preservation Inc501(c)(3)1976$446,344$4.9 million2025-12
Womens Enrichment CenterHealth care501(c)(3)1997$438,259$212,4262024-12
African Christians Fellowship International IncReligion-related501(c)(3)1995$420,271$369,0792025-12
Lancaster County Council of the ArtsArts, culture and humanities501(c)(3)1978$417,759$672,8622025-06
Finding SerenityCommunity improvement and capacity building501(c)(3)2025$361,167$31,1812025-12
United Way of Lancaster County IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)1972$345,064$315,5332025-06
Paws in the Panhandle Rescue and AdoptionAnimal-related501(c)(3)2010$262,060$1.4 million2024-12
Horse N Around Therapeutic Riding CenterHuman services501(c)(3)2010$261,837$219,6742024-12
Beeyond BordersPublic and societal benefit501(c)(3)2023$237,816$138,8852025-12
Southeastern Regional Genetics Group IncMedical research501(c)(3)2002$207,661$379,9872025-12
Katawba Valley Land TrustEnvironment501(c)(3)1995$205,614$10.1 million2024-12
All for One MinistriesReligion-related501(c)(3)2015$198,905$485,1222023-12
Indian Land High School Band Boosters IncEducation501(c)(3)2021$187,764$102,0932025-12
Forerunners Nationchangers InternationalReligion-related501(c)(3)2013$173,086$5,5122024-12
Simple Faith FarmReligion-related501(c)(3)2018$165,129$119,4982024-12
South Carolina Society of Ophthalmology Inc501(c)(6)1997$152,381$406,4462025-12
ShelteredHuman services501(c)(3)2021$129,027$225,2082024-12
Seths Giving TreeEducation501(c)(3)2020$128,216$313,2592025-06
Kings and Queens InternationalHuman services501(c)(3)2015$112,705$100,2552025-12
Lancaster Dixie Baseball IncRecreation and sports501(c)(3)1979$110,306$28,2512025-08
Captain John P Monahan Post VFW 12136Public and societal benefit501(c)(19)2022$106,678$594,2622026-06
Lancaster Lodge No 1646 Loyal Order of Moose501(c)(8)1940$98,401$572,1422026-04
Lindsay Pettus Greenway IncRecreation and sports501(c)(3)2015$96,036$3.8 million2025-12
Rob FoundationPublic and societal benefit501(c)(3)2022$82,143$69,5292025-12
McGill Rose GardenEnvironment501(c)(3)1996$75,316$104,5562025-12
Van Wyck Elementary School PtoEducation501(c)(3)2019$67,508$80,4772025-06
American Legion501(c)(19)1946$65,895$423,0892025-12
Rotary InternationalMutual and membership benefit501(c)(4)1942$65,212$23,9082025-06
Lancaster County Farm Bureau501(c)(5)1973$64,982$487,2002024-12
Rotary International501(c)(4)1942$62,498$66,3082025-06
Missionary Transport Inc501(c)(3)1976$50,198$285,1522025-12
Lancaster County Community CenterCommunity improvement and capacity building501(c)(3)2014$48,008$242,6212025-12
Habitat for Humanity International Inc501(c)(3)1987$44,190$756,6442025-06
Columbus Parker Track Club501(c)(3)1994$37,847$13,8442025-12
South Carolina Tax Council IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)1998$36,859$59,7542025-06
Big Thursday of Lancaster IncHuman services501(c)(3)2013$31,748$40,0872025-12
Matt Blackwell Foundation IncEducation501(c)(3)2002$13,891$16,8402025-12
Unique Hair Design-The SchoolEducation501(c)(3)2016$2,399$12025-12
Tri-County Empowerment Foundation IncHuman services501(c)(3)2024$2,000$2,0002024-12
Humane Society of Lancaster SCAnimal-related501(c)(3)2009$1,536$2,8782024-06
SC State Guard Mission & Operations Support Foundation IncPublic and societal benefit501(c)(3)2018$866$172,4422025-12
Barr Street High School FoundationCommunity improvement and capacity building501(c)(3)2014$484$16,0892025-12
Tirzah Cemetery Association Inc501(c)(13)1950$7$71,1202025-08
Alive To Inspire Ministries501(c)(3)1991$0$02024-12
Alpha CommissionCommunity improvement and capacity building501(c)(3)2022$0$02025-12
American Legion Auxiliary501(c)(19)1945$0$02025-09
Ancient Free Masons of South Carolina501(c)(10)1940$0$02025-12
Ancient Free Masons of South Carolina501(c)(10)1940$0$02025-12
Ancient Free Masons of South Carolina501(c)(10)1940$0$02025-12
Ancient Free Masons of South Carolina501(c)(10)1940$0$02025-12
Antioch Baptist Church501(c)(3)1964
Arrowood Swim ClubRecreation and sports501(c)(3)2019$0$02025-12
Bat Community Tennis FoundationRecreation and sports501(c)(3)2026
Beacon Baptist Church of Lancaster South Carolina501(c)(3)1975
Beauty From GraceCommunity improvement and capacity building501(c)(3)2025$0$02025-12
Believe Christian AcademyHuman services501(c)(3)2010$0$02024-12
Bethel Baptist Church501(c)(3)1964
Bethlehem Baptist Church501(c)(3)1964
Biblical Discovery MinistriesReligion-related501(c)(3)2002
Big Give Back IncYouth development501(c)(3)2018$0$02024-12
Blacet MinistriesHuman services501(c)(3)2006$0$02024-12
Bob M Cook FoundationYouth development501(c)(3)2022$0$02025-12
Brandy Shiloh MinistriesHuman services501(c)(3)2024$0$02025-12
Buford Elementary Parent Teacher OrganizationEducation501(c)(3)2001$0$02025-12
Caleb Henson Memorial FoundationEducation501(c)(3)2024
Call Me Beauty Mentoring ProgramYouth development501(c)(3)2024$0$02025-06
Calvary Baptist Church501(c)(3)1964
Camp Creek Baptist Church501(c)(3)1964
Camryn Olivia Foundation IncorporatedHuman services501(c)(3)2023$0$02025-12
Cannan Land Ministries501(c)(3)
Carolina Elite PanthersYouth development501(c)(3)2023$0$02025-12
Carolina Mental Health InitiativeMental health and crisis intervention501(c)(3)2023$0$02024-12
Catawba Baptist Church501(c)(3)1964
Catawba Presbytery501(c)(3)1967
Cedar Creek MethodistReligion-related501(c)(3)2007
Charlotte Newcomers Club501(c)(7)1980$0$02026-03
Christ Cornerstone Community ChurchReligion-related501(c)(3)2025
Christ Episcopal Church501(c)(3)1971
Christian Faith Outreach MinistriesReligion-related501(c)(3)2006
Church of God of Prophecy Bible Place501(c)(3)1969
Church of the Living God Ministry501(c)(3)1992
Coach Tate National Educational Athletics Association CorporationEducation501(c)(3)2016$0$02024-12
Cogito Academy PtoEducation501(c)(3)2026
Community Care ServiceHuman services501(c)(3)2026$0$02025-06
Community GuardiansHousing and shelter501(c)(3)2022$0$02025-12
Community Partnership Consulting GroupCommunity improvement and capacity building501(c)(3)2025
Community Playhouse of Lancaster County IncArts, culture and humanities501(c)(3)2004$0$02025-12
Coreys LoveMental health and crisis intervention501(c)(3)2026$0$02025-12
Covenant Baptist Church501(c)(3)19642013-12
Covenant Life Word ChurchReligion-related501(c)(3)2013
Covenant Victory Ministries IncReligion-related501(c)(3)2001
Craig Farm Historic Preservation FoundationArts, culture and humanities501(c)(3)2016$855,2952025-12
Creative Synergy FoundationArts, culture and humanities501(c)(3)2025
Crestview Baptist Church501(c)(3)1964
Crusades for Jesus Center Incorporated501(c)(3)1988
David Blackwell Law FoundationEducation501(c)(3)2019$0$02025-12
Defender Corporation of Lancaster CountiesCrime and legal-related501(c)(3)1979
Deliverance Word of Faith ChurchReligion-related501(c)(3)2000
Delta Sigma Theta Sorority Inc501(c)(7)1952
Destiny Bible Church IncReligion-related501(c)(3)2003
Disabled American VeteransPublic and societal benefit501(c)(4)1942$0$02026-06
Dr Trevor Althof Memorial ScholarshipEducation501(c)(3)2020$0$02025-04
Dress Look Act Become Successful IncHuman services501(c)(3)2017$0$02025-12
Eastside Baptist Church501(c)(3)1964
Ebenezer Baptist Church501(c)(3)1964
Elgin Baptist Church501(c)(3)1964
Encouragement Now Ministries IncReligion-related501(c)(3)2021$0$02025-12
Enfoque CiudadReligion-related501(c)(3)2010
Eta Theta Chappter House Corporation Sigma Chi FraternityRecreation and sports501(c)(7)2024$0$02025-12
Faith Hope & Victory Christian ChurchReligion-related501(c)(3)2001
Family 2 Families Connect and ServicesHuman services501(c)(3)2023$0$02025-12
Fellowship Bible ChurchReligion-related501(c)(3)1997
Fellowship CarolinaReligion-related501(c)(3)2021
First Arp Church501(c)(3)1967
First Washington Baptist Church IncReligion-related501(c)(3)1998
Foundry Youth Mentorship and FellowshipYouth development501(c)(3)2025
Friends of Andrew Jackson Statepark IncRecreation and sports501(c)(3)2022$0$02026-04
Friends of the American Legion Inda in LandHuman services501(c)(3)2025$0$02025-12
Garden Club of South Carolina Inc501(c)(3)2011$0$02026-04
Glenwood Heights Baptist Church501(c)(3)1964
Grace Free Will Baptist Church501(c)(3)1973
Greater New Hope Christian AssociationReligion-related501(c)(3)1997
Greater Victory Er CenterReligion-related501(c)(3)2024$0$02025-12
Greater Works Outreach MinistryReligion-related501(c)(3)2012
Harvesttime Assembly of God Inc501(c)(3)1964
Heart of Gold Autism FoundationDiseases, disorders and medical disciplines501(c)(3)2026
Hewett MinistriesPublic and societal benefit501(c)(3)2006$0$02025-12
High Pointbaptist Church of the Moriah Assoc Inc501(c)(3)1964
Holy Church of ChristReligion-related501(c)(3)2020$0$02023-12
Hope Center Church of God of Prophecy501(c)(3)1969
Hope On the HillHuman services501(c)(3)2005$0$02025-12
Hyde Park Baptist Church501(c)(3)1964
Iglesia El SiloeReligion-related501(c)(3)20142025-12
Iglesia Pentecostal El Cordero de DiosReligion-related501(c)(3)2017
Immanuel Baptist Church501(c)(3)1964
In Focus Ministries Incorporated501(c)(3)1991$0$02024-12
Indian Land High School Parent Teacher Student OrganizationEducation501(c)(3)2019$0$02026-06
Indian Land Presbyterian Church in America501(c)(3)1974
International Association of Lions Club501(c)(4)1940$0$02026-06
International Pentecostal Holiness Church501(c)(3)1964
J White Community Development Charitable CorporationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2026$0$02025-12
Jazzs Wayward KittiesAnimal-related501(c)(3)2021$0$02025-12
Jeannetta Renee Girls TalkReligion-related501(c)(3)2017$0$02024-12
John Calvin Bible Foundation IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2000$21.3 million2025-06
Jones Crossroads Baptist Church501(c)(3)1964
Kappa Pi Chapter of Omega Psi Phi Fraternity Inc501(c)(7)2024
Keishawn Omar Private Family FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2024
Kingdom Encounters Journeys Children ClosetHuman services501(c)(3)2024$0$02025-05
Kingdom of God Church International of South CarolinaReligion-related501(c)(3)1995
Knights Templar of the United States of AmericaReligion-related501(c)(10)1964$0$02025-12
Koinonia Bible ChurchReligion-related501(c)(3)2023
Lancaster County Black Chamber of CommerceCommunity improvement and capacity building501(c)(6)2025
Lancaster County Clemson ClubEducation501(c)(3)2014$0$02026-02
Lancaster County Good Samaritan Scholarship FoundationEducation501(c)(3)2018$0$02025-12
Lancaster County Partners for Youth IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)1996$10.7 million2024-12
Lancaster County Public Facilities CorporationHousing and shelter501(c)(3)2026
Lancaster County Veterans CouncilPublic and societal benefit501(c)(3)2017$0$02025-12
Lancaster Educational Assistance Program IncEducation501(c)(3)2006
Lancaster First Baptist Church501(c)(3)1964
Lancaster First PHC501(c)(3)1964
Lancaster Housing Services IncorporatedHousing and shelter501(c)(3)2021$33,2182024-12
Lancaster Regional Sickle Cell SocietyEducation501(c)(3)2026$0$02025-12
Lancaster Second Baptist Church501(c)(3)1964
Lifeline Ministry of Lancaster Inc501(c)(3)1992
Links of LoveHuman services501(c)(3)2021$0$02025-08
Livis LibraryEducation501(c)(3)2013$0$02025-12
Lounsbury Family FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2010$957,2822025-12
Lynnes Haven of HopeHuman services501(c)(3)2020$0$02025-12
Mentors for ChangeCrime and legal-related501(c)(3)2026
Mission 12 11 IncReligion-related501(c)(3)2011$0$02025-12
Neil McMackin Memorial Scholarship FundEducation501(c)(3)2009$0$02025-12
New Cut Presbyterian Church501(c)(3)1982
New Hope Baptist Church501(c)(3)1964
New Hope MB ChurchReligion-related501(c)(3)2015
New Life Christian Assembly of God501(c)(3)1964
New Zion Baptist ChurchReligion-related501(c)(3)2010
Nifes Uniport North America AlumniPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2017$0$02024-12
Nutramax Family FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2019$12.9 million2025-12
Oak Hill Baptist Church501(c)(3)1964
Open Door Fellowship Inc501(c)(3)1994
Operation Little Brown Dog RescueAnimal-related501(c)(3)2026
Order of the Eastern Star of South CarolinaMutual and membership benefit501(c)(8)1971$0$02025-12
Order of the Eastern Star of South CarolinaMutual and membership benefit501(c)(8)1971$0$02025-12
Our Lady of Grace Catholic Church501(c)(3)1946
P23 MinistriesReligion-related501(c)(3)2024$0$02025-09
Philemon House for Young WomenHuman services501(c)(3)2025
Pink Smile PromiseHealth care501(c)(3)2018$0$02025-12
Pleasant Dale Baptist Church501(c)(3)1964
Power of the Spirit MinistriesReligion-related501(c)(3)2026
Powerhouse MinistriesReligion-related501(c)(3)2001
Prince Hall Grand Lodge Free and Accepted Masons of North Carolina501(c)(8)1983$0$02025-06
Quality Deer Management AssociationAnimal-related501(c)(3)2002
Rays of CompassionReligion-related501(c)(3)2014
Reaching Out for Jesus Christ Ministries Inc501(c)(3)1991
Red Rose City Boxing Big Homie ProgramYouth development501(c)(3)2025
Reformation Lutheran Church501(c)(3)1988
Revolution AcademyEducation501(c)(3)2025$0$02025-12
Rooted Unity FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2024
Royal Arch Masons of South Carolina Grand ChapterReligion-related501(c)(8)1940$0$02025-12
Royal and Select Masters of South Carolina501(c)(8)1940$0$02026-02
Running for RyanHealth care501(c)(3)2023$0$02025-12
S and M FoundationEducation501(c)(3)2016$0$12024-12
Sanctuary for AllCrime and legal-related501(c)(3)2024$0$02024-12
Santiagostrong FoundationHuman services501(c)(3)2022$0$02025-12
Saved By Grace LancasterMental health and crisis intervention501(c)(3)2025$0$02025-12
Shady Oak Loving Care IncHousing and shelter501(c)(3)2003$0$02025-12
Shepherds Care Ministries501(c)(3)1991$0$02021-12
Sherwood Baptist Church501(c)(3)1964
Shiloh Arp Church501(c)(3)1967
Soul Harvest MinistriesReligion-related501(c)(3)2004
South Middle PtoEducation501(c)(3)2021$0$02026-07
Spring Hill Baptist Church501(c)(3)1964
Springdell Baptist Church501(c)(3)1964
St Catherines Catholic Church501(c)(3)1946
St Luke United Methodist ChurchReligion-related501(c)(3)2026
Stem Amateur Radio ClubYouth development501(c)(3)2024$0$02025-12
Still Waters FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2024$574,1582025-12
Stover Legacy Foundation IncEducation501(c)(3)2022$0$02025-12
Synergy Community Development CorporationHuman services501(c)(3)2024$0$02025-12
Taylors Grove Baptist Church501(c)(3)1964
Team JoyReligion-related501(c)(3)2021$0$02025-12
Temple Baptist Church501(c)(3)1964
The Arras FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)1946$77.2 million2022-12
The Church of Lancaster501(c)(3)19792008-12
The Do-Gooders RescueHuman services501(c)(3)2026
The PantryFood, agriculture and nutrition501(c)(3)2025
Toastmasters International501(c)(3)1945$0$02025-09
Tour Delux Rally IncHuman services501(c)(3)2021$0$02025-12
Tree Tops Jackpot Bingo ClubRecreation and sports501(c)(3)2026
Tree Tops You Got This ClubMedical research501(c)(3)2023$12025-12
Triapla Research InstituteReligion-related501(c)(3)2021$0$02025-09
Trumpet Call International Ministri EsReligion-related501(c)(3)2026
Union Baptist Church501(c)(3)19642025-12
United Gospel Temple501(c)(3)1977
United States Pony Clubs IncRecreation and sports501(c)(3)2002$0$02025-12
Unity Softball Carolinas ClarkRecreation and sports501(c)(3)2024$0$02025-12
Uprising Supportive ServicesYouth development501(c)(3)2024$0$02025-12
Veterans Breakfast Group of Lancast Er S CHuman services501(c)(3)2026
Village and Vessel MinistriesHuman services501(c)(3)2024$0$02026-04
Vision DreamersInternational, foreign affairs and national security501(c)(3)2025$0$02026-03
Walts Chapel501(c)(3)1991
Westside Baptist Church501(c)(3)1964
White Springs Baptist Church501(c)(3)1964
Womens Center for Personal Development IncHuman services501(c)(3)2019$0$02025-12
Zeta Phi Beta Sorority Inc501(c)(7)1960$0$02024-12

By cause in Lancaster, SC

Nonprofits in every city of the state

Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.