Data / Nonprofits / South Carolina / Columbia
Nonprofits in Columbia, SC: 2,773 registered with the IRS
2,773 nonprofits are registered with the IRS in Columbia, SC, 2,342 of them 501(c)(3) charities; the 907 that report revenue took in $4.37 billion. The largest by revenue: Central Electric Power Cooperative Inc ($1.61 billion), Charter Institute at Erskine ($299.9 million), Welvista ($96 million). Most common causes: education (310), human services (300), religion-related (298).
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The 500 largest by revenue
| Organization | Category | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|
| Central Electric Power Cooperative Inc | 501(c)(12) | 1954 | $1.61 billion | $558.9 million | 2024-12 | |
| Charter Institute at Erskine | Education | 501(c)(3) | 2019 | $299.9 million | $17.4 million | 2025-06 |
| Welvista | Health care | 501(c)(3) | 1998 | $96 million | $48.7 million | 2025-06 |
| Presbyterian Communities of South Carolina | Human services | 501(c)(3) | 1959 | $87.6 million | $183.7 million | 2025-12 |
| University of South Carolina Educational Foundation | Education | 501(c)(3) | 1962 | $85.1 million | $856.9 million | 2025-06 |
| Eau Claire Cooperative Health Center Inc | 501(c)(3) | 1993 | $76.9 million | $33.7 million | 2024-12 | |
| Genesis Healthcare Inc | Health care | 501(c)(3) | 2010 | $76.3 million | $166.8 million | 2025-06 |
| Agfirst-Fcbt Employee Welfare Benefit Trust | Mutual and membership benefit | 501(c)(9) | 1995 | $74.2 million | $6.4 million | 2024-12 |
| South Carolina First Steps To School Readiness Board of Trustees | Education | 501(c)(3) | 2000 | $72.4 million | $34.7 million | 2025-06 |
| Southern Mutual Church Insurance Company | Mutual and membership benefit | 501(c)(4) | 1983 | $72 million | $81.1 million | 2025-12 |
| Columbia International University | Education | 501(c)(3) | 1937 | $71 million | $104.5 million | 2025-06 |
| South Carolina Connections Academy Inc | Education | 501(c)(3) | 2010 | $61.8 million | $34.8 million | 2025-06 |
| South Carolina Student Loan Corporation | Public and societal benefit | 501(c)(3) | 1975 | $58.4 million | $892.3 million | 2025-06 |
| Gamecock Club | Education | 501(c)(3) | 2024 | $56.4 million | $32.5 million | 2025-06 |
| Benedict College | Education | 501(c)(3) | 1945 | $52.8 million | $143.9 million | 2024-06 |
| Harvest Hope Food Bank | Food, agriculture and nutrition | 501(c)(3) | 1982 | $50.5 million | $30.4 million | 2024-06 |
| Central Carolina Community Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1987 | $47.1 million | $264.3 million | 2025-06 |
| University of South Carolina School of Medicine Educational Trust | Education | 501(c)(3) | 1980 | $44.2 million | $62.9 million | 2025-06 |
| Columbia College | Education | 501(c)(3) | 1950 | $37.5 million | $58.5 million | 2025-06 |
| Richland County Public Library | Education | 501(c)(3) | 1982 | $37.4 million | $26.3 million | 2025-06 |
| Cahec Management Inc | Housing and shelter | 501(c)(3) | 2020 | $37.4 million | $9.7 million | 2024-12 |
| Scbma | Human services | 501(c)(3) | 1961 | $31.6 million | $52.3 million | 2025-09 |
| Wateree Community Actions Inc | Human services | 501(c)(3) | 2017 | $30.4 million | $14.1 million | 2024-12 |
| Heathwood Hall Episcopal School | Education | 501(c)(3) | 1971 | $29.4 million | $74.5 million | 2025-06 |
| South Carolina Property and Casualty Insurance Guaranty Assoc | 501(c)(6) | 1975 | $28.1 million | $68.8 million | 2024-12 | |
| Hammond School | Education | 501(c)(3) | 1984 | $27.2 million | $75.5 million | 2025-06 |
| South Carolina Youth Advocate Program Inc | Human services | 501(c)(3) | 1991 | $26.6 million | $69.6 million | 2025-12 |
| South Carolina Medical Association Members Insurance Trust | Mutual and membership benefit | 501(c)(9) | 2013 | $26.3 million | $22.6 million | 2025-06 |
| Allen University | Education | 501(c)(3) | 1946 | $22.6 million | $63.6 million | 2025-06 |
| Epworth Childrens Home | Human services | 501(c)(3) | 1950 | $22.1 million | $64.5 million | 2025-12 |
| University of South Carolina Development Foundation | Education | 501(c)(3) | 1966 | $22.1 million | $408.9 million | 2025-06 |
| Childrens Trust Fund of South Carolina | Human services | 501(c)(3) | 1985 | $21.3 million | $14.5 million | 2025-09 |
| South Carolina Education Futures | Education | 501(c)(3) | 2024 | $20.4 million | $4.7 million | 2025-06 |
| Municipal Association of South Carolina | 501(c)(4) | 1945 | $19.2 million | $41.1 million | 2025-12 | |
| University of South Carolina Business Partnership Foundation | 501(c)(3) | 1969 | $17.3 million | $173.2 million | 2025-06 | |
| South Carolina Research Authority | Science and technology | 501(c)(3) | 1987 | $16.2 million | $101.5 million | 2023-06 |
| TMPC Nonprofit Holdings Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(2) | 2016 | $14.4 million | $14.7 million | 2024-12 |
| Forest Lake Club | Recreation and sports | 501(c)(7) | 1964 | $14.2 million | $19.2 million | 2025-10 |
| United Way of the Midlands | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1955 | $14.1 million | $29.5 million | 2025-06 |
| Alston Wilkes Society | 501(c)(3) | 1964 | $13.7 million | $5.5 million | 2024-12 | |
| South Carolina Legal Services | Crime and legal-related | 501(c)(3) | 1977 | $13.3 million | $17.2 million | 2025-12 |
| One Nation Innovation | Science and technology | 501(c)(3) | 2022 | $13 million | $2.2 million | 2024-12 |
| Lexington-Richland Alcohol & Drug Abuse Council Inc | Mental health and crisis intervention | 501(c)(3) | 1969 | $12.2 million | $17.1 million | 2025-06 |
| South Carolina Association of Community Action Partnerships | 501(c)(3) | 2004 | $11.8 million | $10.7 million | 2025-12 | |
| South Carolina Bar | 501(c)(6) | 1976 | $11.7 million | $27 million | 2025-06 | |
| Prisma Health Midlands Foundation | Health care | 501(c)(3) | 1982 | $11.7 million | $61.6 million | 2025-09 |
| State Agricultural & Mechanical Society of South Carolina | Recreation and sports | 501(c)(3) | 1969 | $11.2 million | $39.6 million | 2025-12 |
| South Carolina Dental Association Group Ins Trust | Mutual and membership benefit | 501(c)(9) | 2018 | $10.8 million | $169,072 | 2025-01 |
| South Carolina Automobile Dealers Trust | 501(c)(9) | 1983 | $10.4 million | $477,088 | 2025-11 | |
| Boys & Girls Clubs of the Midlands | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2019 | $8.7 million | $1.4 million | 2025-06 |
| Center of Excellence for Educator Preparation and Innovation Inc | Education | 501(c)(3) | 2022 | $8.4 million | $5.8 million | 2025-09 |
| South Carolina Bar Foundation Inc | Crime and legal-related | 501(c)(3) | 1972 | $8.3 million | $34.1 million | 2025-06 |
| South Carolina State Firefighters Association Group Insurance Trust | Mutual and membership benefit | 501(c)(9) | 2019 | $8.2 million | $101,223 | 2025-07 |
| Riverbanks Society | Animal-related | 501(c)(3) | 1974 | $8 million | $7.8 million | 2025-06 |
| SC Thrive | Science and technology | 501(c)(3) | 2014 | $8 million | $9.4 million | 2025-12 |
| Mental Illness Recovery Center Inc | 501(c)(3) | 1962 | $7.7 million | $7.1 million | 2025-12 | |
| Columbia Metropolitan Convention and Visitors Bureau | 501(c)(6) | 1988 | $7.6 million | $10.9 million | 2025-06 | |
| SC Manufacturers Alliance Group Ins Trust | Mutual and membership benefit | 501(c)(9) | 2021 | $7.6 million | $561,999 | 2025-06 |
| Pawmettolifeline Inc | Animal-related | 501(c)(3) | 1999 | $7.5 million | $10.5 million | 2024-12 |
| South Carolina First Steps To School Readiness Board of Trustees | Education | 501(c)(3) | 2000 | $7.4 million | $1.4 million | 2025-06 |
| Clear Dot Charter School Columbia | Education | 501(c)(3) | 2018 | $7.3 million | $1.3 million | 2025-06 |
| South Carolina Hospital Association | 501(c)(6) | 1959 | $7.2 million | $23.2 million | 2024-12 | |
| South Carolina High School League | 501(c)(3) | 1950 | $6.9 million | $4.3 million | 2025-06 | |
| Curis Financial Credit Union | 501(c)(14) | 1968 | $6.8 million | $87.1 million | 2025-12 | |
| New Morning | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2002 | $6.7 million | $4.4 million | 2025-06 |
| Palmetto Aids Life Support Services | 501(c)(3) | 1987 | $6.7 million | $3.7 million | 2025-06 | |
| South Carolina School Boards Association | Education | 501(c)(3) | 1963 | $6.6 million | $10.7 million | 2026-06 |
| United Way Association of South Carolina Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1970 | $6.5 million | $3.5 million | 2024-12 |
| Palmetto Utility Protection Service Inc | 501(c)(6) | 1990 | $6.5 million | $3.6 million | 2025-12 | |
| National Educational Telecommunications Association | Arts, culture and humanities | 501(c)(3) | 1968 | $6.5 million | $2.8 million | 2025-06 |
| Primary Care Association of SC Inc | Health care | 501(c)(3) | 1986 | $6.5 million | $4.8 million | 2025-03 |
| Edventure Inc | Arts, culture and humanities | 501(c)(3) | 1995 | $6.3 million | $9.9 million | 2025-06 |
| Home Builders Association of South Carolina Group Trust Insurance | Mutual and membership benefit | 501(c)(9) | 2022 | $6.3 million | $132,562 | 2025-07 |
| Brighter Future Employment Services | Employment | 501(c)(3) | 2018 | $6.3 million | $1.1 million | 2025-06 |
| Oliver Gospel Mission | Religion-related | 501(c)(3) | 1967 | $6.2 million | $19.3 million | 2025-09 |
| Columbia Museum of Art | Arts, culture and humanities | 501(c)(3) | 1962 | $6.2 million | $23.5 million | 2025-06 |
| South Carolina Association of Realtors | 501(c)(6) | 1964 | $5.6 million | $14.7 million | 2024-12 | |
| University of South Carolina Alumni Association | Education | 501(c)(3) | 1977 | $5.5 million | $20.5 million | 2025-06 |
| Columbia Empowerment Zone Inc | Community improvement and capacity building | 501(c)(3) | 2008 | $5.4 million | $17.8 million | 2025-06 |
| South Carolina Research Foundation | 501(c)(3) | 1993 | $5.3 million | $2.4 million | 2025-06 | |
| Boys & Girls Clubs of the Crescent Region | 501(c)(3) | 1961 | $5.3 million | $2.3 million | 2025-06 | |
| South Carolina Trucking Association Inc Group Insurance Trust | Mutual and membership benefit | 501(c)(9) | 2018 | $5.3 million | $113,015 | 2025-01 |
| Able South Carolina | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1999 | $5 million | $3.7 million | 2025-09 |
| Investsc Inc | Community improvement and capacity building | 501(c)(3) | 2007 | $5 million | $22.5 million | 2025-12 |
| PCSC Foundation | Crime and legal-related | 501(c)(3) | 2010 | $4.7 million | $43.7 million | 2025-12 |
| Together SC Group Ins Trust | Mutual and membership benefit | 501(c)(9) | 2023 | $4.7 million | $302,169 | 2025-12 |
| Cooperative Ministry | Human services | 501(c)(3) | 1988 | $4.7 million | $3.8 million | 2025-06 |
| Midlands Housing Alliance Inc | 501(c)(3) | 2005 | $4.7 million | $15 million | 2025-06 | |
| Garnet Trust Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2022 | $4.7 million | $113,190 | 2024-12 |
| South Carolina Dealer Services LLC | Community improvement and capacity building | 501(c)(6) | 2021 | $4.6 million | $3.8 million | 2025-06 |
| Palmetto Economic Development Corp | 501(c)(3) | 1989 | $4.6 million | $3.3 million | 2024-12 | |
| South Carolina State Firemans Association | 501(c)(4) | 1965 | $4.5 million | $8.9 million | 2025-09 | |
| Crossover Communications International Inc | Religion-related | 501(c)(3) | 2008 | $4.4 million | $5.2 million | 2024-12 |
| Jubilee Academy Inc | Human services | 501(c)(3) | 2001 | $4.4 million | $3.9 million | 2024-12 |
| Senior Resources Inc | Human services | 501(c)(3) | 1967 | $4.3 million | $6.5 million | 2025-06 |
| University Industry Demonstration Partnership Inc | Science and technology | 501(c)(3) | 2015 | $4.3 million | $2 million | 2025-06 |
| Sistercare Inc | 501(c)(3) | 1982 | $4.1 million | $3.1 million | 2024-12 | |
| Vision Center | Religion-related | 501(c)(3) | 2023 | $4.1 million | $4.4 million | 2024-12 |
| South Carolina Whitmore School | Education | 501(c)(3) | 2013 | $4.1 million | $4.4 million | 2025-06 |
| Scha Foundation Inc | 501(c)(3) | 1965 | $4.1 million | $10.4 million | 2024-12 | |
| South Carolina Association of School Administrators | 501(c)(6) | 1979 | $4.1 million | $8 million | 2025-06 | |
| Columbia United FC | 501(c)(3) | 1988 | $4 million | $7.2 million | 2025-05 | |
| Palmetto State Growth Fund Inc | Public and societal benefit | 501(c)(3) | 2019 | $4 million | $24.2 million | 2024-12 |
| Easter Seal Society of South Carolina Inc | 501(c)(3) | 1980 | $4 million | $3.4 million | 2026-06 | |
| South Carolina Educational Credit for Exceptional Needs Children Fun | Education | 501(c)(3) | 2016 | $3.9 million | $2.1 million | 2025-06 |
| South Carolina First Steps To School Readiness Board of Trustees | Education | 501(c)(3) | 2000 | $3.9 million | $544,364 | 2025-06 |
| Palmetto Achievement Center for Exc Ellence Academy Inc | Education | 501(c)(3) | 2020 | $3.8 million | $6.5 million | 2025-06 |
| Central South Carolina Habitat for Humanity Inc | 501(c)(3) | 1985 | $3.8 million | $6.4 million | 2025-06 | |
| South Carolina Automobile and Truck Dealers Association | 501(c)(6) | 1942 | $3.8 million | $8.8 million | 2025-06 | |
| Paymentsfirst Inc | 501(c)(6) | 1988 | $3.7 million | $2.6 million | 2024-12 | |
| South Carolina Rural Water Association | Environment | 501(c)(3) | 1977 | $3.7 million | $1.7 million | 2025-12 |
| South Carolina Medical Association | Mutual and membership benefit | 501(c)(6) | 1941 | $3.7 million | $7.6 million | 2025-06 |
| Family Connection of South Carolina Inc | Human services | 501(c)(3) | 1990 | $3.6 million | $2.7 million | 2025-06 |
| Harbison Community Association Inc | 501(c)(4) | 1976 | $3.6 million | $3.2 million | 2025-12 | |
| Sandhills School | 501(c)(3) | 1977 | $3.5 million | $9.8 million | 2026-06 | |
| Spring Valley Country Club | 501(c)(7) | 1965 | $3.5 million | $3.6 million | 2025-04 | |
| Humane Society for the Prevention | Animal-related | 501(c)(3) | 1967 | $3.4 million | $5.5 million | 2025-06 |
| The Palmetto Club of Columbia | 501(c)(7) | 1962 | $3.4 million | $3.9 million | 2025-06 | |
| National Association for Campus Activities | 501(c)(4) | 1980 | $3.4 million | $2.8 million | 2026-04 | |
| South Carolina Bankers Association | 501(c)(6) | 1942 | $3.4 million | $7.8 million | 2025-06 | |
| South Carolina Manufacturers and Commerce | 501(c)(6) | 1941 | $3.2 million | $3.5 million | 2025-09 | |
| South Carolina Network of Childrens Advocacy Centers | Youth development | 501(c)(3) | 2006 | $3.2 million | $1.5 million | 2025-12 |
| Childrens Center at Usc | Education | 501(c)(3) | 2006 | $3.2 million | $20,407 | 2025-06 |
| Historic Columbia Foundation Inc | Arts, culture and humanities | 501(c)(3) | 1963 | $3.1 million | $4.3 million | 2025-06 |
| South Carolina Association for Justice | 501(c)(6) | 1974 | $3.1 million | $3 million | 2025-06 | |
| Fact Forward | Education | 501(c)(3) | 1996 | $3 million | $957,291 | 2025-09 |
| Health Sciences South Carolina | Health care | 501(c)(3) | 2021 | $3 million | $2.6 million | 2025-06 |
| Palmetto Conservation Foundation | Environment | 501(c)(3) | 1990 | $3 million | $6.6 million | 2025-06 |
| Carolinas Credit Union League | 501(c)(6) | 1943 | $2.9 million | $6.4 million | 2024-12 | |
| Columbia Housing Authority Developments Inc | 501(c)(3) | 1988 | $2.9 million | $9.7 million | 2024-06 | |
| Columbia College Foundation Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2007 | $2.8 million | $11.5 million | 2025-06 |
| Cure Sanfilippo Foundation | Medical research | 501(c)(3) | 2014 | $2.8 million | $13.9 million | 2024-12 |
| Conservation Voters of So Carolina | 501(c)(4) | 1998 | $2.7 million | $1.3 million | 2024-12 | |
| Family Preservation Community Services | Human services | 501(c)(3) | 1999 | $2.6 million | $10.8 million | 2025-06 |
| The Therapy Place Inc | Youth development | 501(c)(3) | 2008 | $2.6 million | $1.7 million | 2025-06 |
| Vital Connections of the Midlands Inc | Human services | 501(c)(3) | 2004 | $2.5 million | $1.3 million | 2025-06 |
| Columbia Facilities Corporation | Community improvement and capacity building | 501(c)(3) | 2026 | $2.5 million | $90.7 million | 2025-06 |
| Disability Rights South Carolina Inc | Civil rights, social action and advocacy | 501(c)(3) | 1979 | $2.5 million | $1.3 million | 2025-09 |
| Episcopal Housing Corporation | 501(c)(4) | 1971 | $2.5 million | $4.5 million | 2024-12 | |
| Original Six Foundation | Community improvement and capacity building | 501(c)(3) | 2012 | $2.5 million | $2.3 million | 2025-06 |
| Boy Scouts of America | Youth development | 501(c)(3) | 1965 | $2.5 million | $2.4 million | 2024-12 |
| Carolinas Credit Union Foundation Inc | Education | 501(c)(3) | 1998 | $2.4 million | $5.5 million | 2025-12 |
| South Carolina Council On Competitiveness | Community improvement and capacity building | 501(c)(3) | 2005 | $2.4 million | $3.3 million | 2025-06 |
| Beta Zeta House Corporation | Community improvement and capacity building | 501(c)(2) | 2003 | $2.4 million | $7.5 million | 2025-12 |
| Central Carolina Economic Development Alliance | Community improvement and capacity building | 501(c)(3) | 1996 | $2.4 million | $3.3 million | 2025-06 |
| North Flint Reinvestment Corporation | Human services | 501(c)(3) | 2014 | $2.3 million | $1.8 million | 2025-09 |
| South Carolina Ballet Inc | Arts, culture and humanities | 501(c)(3) | 1976 | $2.3 million | $769,801 | 2025-03 |
| Campus Outreach Columbia | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2024 | $2.2 million | $685,017 | 2025-12 |
| The Meeting Place Church International | Religion-related | 501(c)(3) | 2014 | $2.2 million | $3.4 million | 2025-12 |
| Homeless No More Inc | Housing and shelter | 501(c)(3) | 1990 | $2.2 million | $8.1 million | 2024-09 |
| Carolina School for Inquiry | Education | 501(c)(3) | 2008 | $2.2 million | $2.8 million | 2025-06 |
| City Center Partnership Inc | Community improvement and capacity building | 501(c)(6) | 2001 | $2.1 million | $1.2 million | 2025-06 |
| South Carolina Health Care Association | 501(c)(6) | 1965 | $2.1 million | $967,649 | 2024-12 | |
| United Housing Associates Inc | Health care | 501(c)(3) | 1994 | $2.1 million | $10.7 million | 2025-12 |
| South Carolina Governors School for Sci & Math Foundation Inc | Education | 501(c)(3) | 1990 | $2.1 million | $17.5 million | 2025-06 |
| Serve and Connect | Human services | 501(c)(3) | 2017 | $2.1 million | $1.2 million | 2025-06 |
| Wildwood Communty Neighborhood Inc | 501(c)(7) | 2020 | $2.1 million | $985,446 | 2024-12 | |
| Palmettopride the Governors Council On Beautification & Litter | Environment | 501(c)(3) | 1999 | $2.1 million | $3.1 million | 2025-06 |
| Midlands Fatherhood Coalition | Recreation and sports | 501(c)(3) | 2002 | $2.1 million | $532,905 | 2025-09 |
| TN Development Corp | Housing and shelter | 501(c)(3) | 1994 | $2.1 million | $5.6 million | 2025-06 |
| South Carolina Philharmonic Inc | Arts, culture and humanities | 501(c)(3) | 1983 | $2.1 million | $1.3 million | 2025-06 |
| First Presbyterian Church Counseling Center Inc | Mental health and crisis intervention | 501(c)(3) | 1996 | $2 million | $272,738 | 2025-12 |
| South Carolina United Methodist Foundation | 501(c)(3) | 1979 | $2 million | $34 million | 2025-06 | |
| Association for Education in Journalism and Mass Communication | Arts, culture and humanities | 501(c)(3) | 1952 | $2 million | $2.5 million | 2025-09 |
| South Carolina Victim Assistance Network Inc | 501(c)(3) | 1988 | $2 million | $572,140 | 2025-06 | |
| Richland One Middle College at Midlands Technical College | 501(c)(3) | 2014 | $2 million | $1.9 million | 2025-06 | |
| Independent Insurance Agents & Brokers of South Carolina | 501(c)(6) | 1943 | $2 million | $2.2 million | 2024-12 | |
| Child Evangelism Fellowship Inc | Youth development | 501(c)(3) | 1956 | $2 million | $1.1 million | 2025-12 |
| American Civil Liberties Union of South Carolina Foundation Inc | Civil rights, social action and advocacy | 501(c)(3) | 2011 | $1.9 million | $3.6 million | 2025-03 |
| Fortify Foundation | Education | 501(c)(3) | 2020 | $1.9 million | $6.7 million | 2024-12 |
| South Carolina State Museum Foundation | Arts, culture and humanities | 501(c)(3) | 1981 | $1.9 million | $6.4 million | 2025-06 |
| Midlands Technical College Foundation Inc | Education | 501(c)(3) | 1970 | $1.9 million | $21.4 million | 2025-06 |
| South Carolina Tennis Association Inc | 501(c)(4) | 1978 | $1.9 million | $2.6 million | 2024-12 | |
| Five Points Foundation Inc | Health care | 501(c)(3) | 2012 | $1.8 million | $968,299 | 2025-06 |
| Agfirst Farm Credit Council Inc | 501(c)(6) | 1984 | $1.8 million | $0 | 2025-12 | |
| Montessori Elementary School of Columbia Inc | Education | 501(c)(3) | 1984 | $1.8 million | $4 million | 2025-06 |
| Final Victory Animal Rescue Inc | 501(c)(3) | 2017 | $1.8 million | $444,123 | 2025-06 | |
| National Federation of the Blind of South Carolina | Diseases, disorders and medical disciplines | 501(c)(3) | 1970 | $1.8 million | $1.9 million | 2024-12 |
| FPCRC Inc | Human services | 501(c)(3) | 1988 | $1.8 million | $29.5 million | 2026-04 |
| Pathways To Healing | Mental health and crisis intervention | 501(c)(3) | 1984 | $1.7 million | $2.7 million | 2025-06 |
| South Carolina Childrens Fund | Education | 501(c)(3) | 2024 | $1.7 million | $981,865 | 2025-12 |
| Reconciliation Ministries SC | Human services | 501(c)(3) | 2004 | $1.7 million | $4.9 million | 2024-12 |
| SC Uplift Community Outreach | Community improvement and capacity building | 501(c)(3) | 2008 | $1.7 million | $546,928 | 2024-12 |
| Columbia Urban League Inc | Human services | 501(c)(3) | 1970 | $1.7 million | $3.4 million | 2024-12 |
| Greater Columbia Chamber of Commerce | 501(c)(6) | 1942 | $1.7 million | $864,537 | 2025-08 | |
| Gates School | Education | 501(c)(3) | 2020 | $1.7 million | $4.8 million | 2023-06 |
| South Carolina Sheriffs Association | 501(c)(3) | 1983 | $1.7 million | $1.9 million | 2025-12 | |
| Medserve | Health care | 501(c)(3) | 2016 | $1.7 million | $1.5 million | 2024-12 |
| South Carolina Trucking Association Inc | 501(c)(6) | 1964 | $1.7 million | $1.7 million | 2025-12 | |
| Lambda Theta House Corporation of Phi Mu Fraternity | Community improvement and capacity building | 501(c)(2) | 2019 | $1.7 million | $3.2 million | 2025-06 |
| Palmetto Place Children & Youth Services | 501(c)(3) | 1964 | $1.6 million | $2.3 million | 2025-12 | |
| National Organization of Rheumatology Managers | Community improvement and capacity building | 501(c)(6) | 2012 | $1.6 million | $3.3 million | 2025-12 |
| Boys & Girls Clubs of Kershaw County | Youth development | 501(c)(3) | 2018 | $1.6 million | $97,889 | 2025-06 |
| Smokefree SC | Health care | 501(c)(3) | 2002 | $1.6 million | $1.2 million | 2025-06 |
| Shandon Weekday School | Education | 501(c)(3) | 2025 | $1.5 million | $568,793 | 2021-12 |
| Ronald McDonald House Charities of Columbia SC | Human services | 501(c)(3) | 1982 | $1.5 million | $5.4 million | 2024-12 |
| Junior Achievement of Greater South Carolina | International, foreign affairs and national security | 501(c)(3) | 1994 | $1.5 million | $2.3 million | 2025-06 |
| National Association of Chapter 13 Trustees | 501(c)(6) | 1988 | $1.5 million | $238,533 | 2025-09 | |
| Columbia Free Medical Clinic | Health care | 501(c)(3) | 1985 | $1.5 million | $1.8 million | 2025-12 |
| SC Future Makers | Education | 501(c)(3) | 2015 | $1.4 million | $941,091 | 2025-06 |
| South Carolina Humanites Council | Arts, culture and humanities | 501(c)(3) | 1985 | $1.4 million | $1.8 million | 2025-10 |
| National Association of State Park Directors | 501(c)(6) | 1998 | $1.4 million | $2 million | 2025-10 | |
| Nami of South Carolina | 501(c)(3) | 1987 | $1.4 million | $854,102 | 2024-12 | |
| South Carolina Medical Association Foundation | 501(c)(3) | 1977 | $1.4 million | $3.3 million | 2025-06 | |
| Invest To Protect Our Law Enforcement Officers Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1995 | $1.4 million | $872,011 | 2025-06 |
| Manufactured Housing Institute of South Carolina | 501(c)(6) | 1970 | $1.4 million | $3.2 million | 2025-12 | |
| Lions Vision Services A South Carolina Charity | Diseases, disorders and medical disciplines | 501(c)(3) | 1971 | $1.4 million | $2.8 million | 2025-06 |
| Business and Industry Coalition Inc and the S Carolina Civil Just Coal | Community improvement and capacity building | 501(c)(6) | 2003 | $1.4 million | $626,333 | 2025-12 |
| South Carolina Dental Association | 501(c)(6) | 1968 | $1.3 million | $3.9 million | 2025-12 | |
| Community Assistance Providers | Housing and shelter | 501(c)(3) | 2001 | $1.3 million | $10.1 million | 2024-12 |
| Harry R E Hampton Memorial Wildlife Fund Inc | 501(c)(3) | 1984 | $1.3 million | $3.2 million | 2024-12 | |
| James R Clark Memorial Sickle Cell Foundation Inc | Diseases, disorders and medical disciplines | 501(c)(3) | 1989 | $1.3 million | $585,856 | 2024-12 |
| Central Carolina Realtors Association | 501(c)(6) | 1963 | $1.3 million | $3.5 million | 2024-12 | |
| Eta Gamma Chapter of Chi Omega Fraternity Housing Corporation | 501(c)(7) | 1987 | $1.3 million | $9.3 million | 2025-06 | |
| Rockbridge Club Inc | 501(c)(7) | 1989 | $1.2 million | $1.4 million | 2025-12 | |
| Home Works of America Inc | Human services | 501(c)(3) | 1998 | $1.2 million | $373,870 | 2024-12 |
| Future Farmers of America and Its State Associations & Local Chapter | Youth development | 501(c)(3) | 1945 | $1.2 million | $321,676 | 2025-12 |
| Republic Risk Retention Group | Mutual and membership benefit | 501(c)(3) | 2005 | $1.2 million | $3.7 million | 2025-12 |
| South Carolina Convenience and Petroleum Marketers Association in | 501(c)(6) | 1957 | $1.2 million | $1.4 million | 2025-12 | |
| Columbia Film Society | Arts, culture and humanities | 501(c)(3) | 1980 | $1.2 million | $1.8 million | 2025-06 |
| South Carolina Asphalt Pavement Association Inc | 501(c)(6) | 1967 | $1.2 million | $1.3 million | 2025-09 | |
| Summit Classical Charter School Inc | Education | 501(c)(3) | 2019 | $1.1 million | $287,819 | 2024-06 |
| Flourishing Families of South Carolina | Human services | 501(c)(3) | 2019 | $1.1 million | $345,660 | 2025-10 |
| South Carolina First Steps To School Readiness Board of Trustees | Education | 501(c)(3) | 2000 | $1.1 million | $430,390 | 2025-06 |
| Home Builders Association of Columbia | 501(c)(6) | 1963 | $1.1 million | $618,055 | 2024-12 | |
| Midlands Community Development Corporation | Housing and shelter | 501(c)(3) | 1999 | $1.1 million | $1.1 million | 2024-12 |
| Varna International Music Academy | Arts, culture and humanities | 501(c)(3) | 2018 | $1.1 million | $168,083 | 2025-07 |
| Sustain South Carolina Intersection Commerce and Conservation | Environment | 501(c)(3) | 2019 | $1.1 million | $908,616 | 2025-12 |
| South Carolina Restaurant and Lodging Association | 501(c)(6) | 1954 | $1.1 million | $442,455 | 2024-12 | |
| Palmetto Promise Institute | Health care | 501(c)(3) | 2009 | $1.1 million | $1.3 million | 2025-12 |
| Auntie Karen Foundation | Youth development | 501(c)(3) | 2003 | $1.1 million | $317,959 | 2025-12 |
| Conservation Voters of South Carolina Education Fund | Environment | 501(c)(3) | 2003 | $1.1 million | $1.1 million | 2024-12 |
| South Carolina Independent Colleges and Universities Inc | Education | 501(c)(3) | 1955 | $1.1 million | $5.7 million | 2025-08 |
| Forestry Association of South Carolina | Environment | 501(c)(6) | 1969 | $1.1 million | $3.1 million | 2024-12 |
| SC Launch Inc | Community improvement and capacity building | 501(c)(3) | 2008 | $1.1 million | $36.6 million | 2025-06 |
| American Fats and Oils Association | 501(c)(6) | 1974 | $1.1 million | $1.4 million | 2024-12 | |
| Independent Ins Agents & Brokers of SC Inc Group Ins Trust | Mutual and membership benefit | 501(c)(9) | 2018 | $1.1 million | $14,671 | 2026-01 |
| South Carolina Junior Golf Foundation | Education | 501(c)(3) | 1996 | $1 million | $2 million | 2024-12 |
| Miss South Carolina Scholarship Organization Inc | Education | 501(c)(4) | 2012 | $1 million | $596,288 | 2025-09 |
| Ezekiel Center Inc | Education | 501(c)(3) | 2014 | $1 million | $367,131 | 2024-12 |
| PSL Foundation | Public and societal benefit | 501(c)(3) | 2022 | $1 million | $664,264 | 2025-06 |
| Together SC | Community improvement and capacity building | 501(c)(3) | 1998 | $993,073 | $405,477 | 2025-06 |
| South Carolina Alliance of Health Plans | 501(c)(6) | 1997 | $988,619 | $734,227 | 2025-12 | |
| SC Chamber Education and Workforce Development Foundation | 501(c)(3) | 1990 | $987,688 | $2.4 million | 2025-09 | |
| Education Express Center for Learning Inc | Education | 501(c)(3) | 2025 | $985,190 | $564,265 | 2021-12 |
| National Institute of Oilseed Products Inc | 501(c)(6) | 1995 | $979,840 | $1.6 million | 2025-12 | |
| Providence Home | 501(c)(3) | 1966 | $965,592 | $4 million | 2025-12 | |
| Usc Columbia Technology Incubator | Community improvement and capacity building | 501(c)(3) | 2012 | $946,846 | $340,947 | 2024-12 |
| Valeo Inc | Religion-related | 501(c)(3) | 1995 | $933,072 | $788,550 | 2025-12 |
| Kennedys Assistive Living & Educational Facility | Human services | 501(c)(3) | 2009 | $913,500 | $52,206 | 2025-12 |
| Pink & Green Community Service Foundation | Community improvement and capacity building | 501(c)(3) | 2014 | $903,979 | $694,330 | 2025-12 |
| South Carolina Institute of Medicine and Public Health | Health care | 501(c)(3) | 2012 | $895,902 | $229,040 | 2025-06 |
| American Legion Dept of SC | 501(c)(19) | 1946 | $882,134 | $2.5 million | 2024-12 | |
| Home Builders Association of South Carolina | 501(c)(6) | 1964 | $880,081 | $574,702 | 2025-12 | |
| Columbia United Jewish Welfare Federation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1982 | $848,174 | $1 million | 2024-12 |
| Credit Unions Chartered in the State of South Carolina | 501(c)(14) | 1968 | $845,891 | $25.8 million | 2025-12 | |
| Hive Community Circle | Human services | 501(c)(3) | 2015 | $838,617 | $41,345 | 2025-06 |
| Womens Rights and Empowerment Network | Human services | 501(c)(3) | 2016 | $828,443 | $2.2 million | 2025-06 |
| Jamil Shriners | 501(c)(10) | 1940 | $810,091 | $1.6 million | 2024-12 | |
| Alpha Gamma Delta Fraternity | 501(c)(7) | 1941 | $801,101 | $273,678 | 2025-06 | |
| South Carolina Pharmaceutical Association | Community improvement and capacity building | 501(c)(6) | 2003 | $796,589 | $2.1 million | 2025-12 |
| Black Pages International | Community improvement and capacity building | 501(c)(3) | 2004 | $796,394 | $29,407 | 2024-12 |
| Chabad-Lubavitch of South Carolina Inc | 501(c)(3) | 1988 | $794,752 | $1.6 million | 2025-06 | |
| Congaree Land Trust | Environment | 501(c)(3) | 1992 | $789,331 | $4.2 million | 2025-06 |
| Palmetto Family Council | Human services | 501(c)(3) | 1993 | $780,223 | $230,753 | 2025-12 |
| Columbia Stage Society | Arts, culture and humanities | 501(c)(3) | 1952 | $779,443 | $2.3 million | 2025-08 |
| South Carolina Beer Wholesalers Assoc | 501(c)(6) | 1949 | $775,390 | $6.5 million | 2025-12 | |
| South Carolina Policy Council Education Foundation | 501(c)(3) | 1987 | $765,589 | $675,021 | 2025-12 | |
| Alston Wilkes Association | 501(c)(2) | 1976 | $765,172 | $3.5 million | 2024-12 | |
| Wine and Spirits Wholesalers Association of South Carolina | Community improvement and capacity building | 501(c)(6) | 2012 | $762,714 | $158,718 | 2025-12 |
| Dignity Housing Association Inc | Housing and shelter | 501(c)(3) | 1979 | $760,523 | $1.5 million | 2024-12 |
| South Carolina Defense Trial Attorneys Association | 501(c)(6) | 1983 | $759,673 | $697,198 | 2025-12 | |
| Brookland Academy Child Development Center | Education | 501(c)(3) | 2005 | $757,576 | $146,411 | 2025-07 |
| Boy Scouts of America | 501(c)(3) | 1965 | $743,359 | $5.1 million | 2024-12 | |
| Mechanical Contractors Association of South Carolina | 501(c)(6) | 1958 | $741,364 | $1.2 million | 2025-05 | |
| Rivers Edge Retreat Inc | Youth development | 501(c)(3) | 2012 | $737,224 | $808,911 | 2024-12 |
| Child Development Center RBC | Youth development | 501(c)(3) | 2013 | $737,087 | $564,993 | 2025-12 |
| Carolina Aquatics Swim Club Inc | Recreation and sports | 501(c)(3) | 2007 | $736,753 | $172,215 | 2026-07 |
| Association of Defense Trial Attorneys | 501(c)(6) | 1958 | $736,289 | $587,445 | 2025-12 | |
| Scientific Equipment & Furniture Association | 501(c)(6) | 1989 | $729,725 | $1 million | 2025-06 | |
| Mission Hope Foundation | Religion-related | 501(c)(3) | 2007 | $720,909 | $1.4 million | 2024-12 |
| R-Lcoa Housing Development Corporation Inc | Housing and shelter | 501(c)(3) | 1980 | $718,392 | $1.9 million | 2024-12 |
| South Carolina Appleseed Legal Justice Center | Civil rights, social action and advocacy | 501(c)(3) | 1996 | $716,979 | $3.8 million | 2024-12 |
| Arrows Academy of South Carolina | Education | 501(c)(3) | 2018 | $715,893 | $474,541 | 2024-06 |
| Kappa Delta Sorority | 501(c)(7) | 1943 | $713,738 | $510,893 | 2025-06 | |
| Work in Progress Inc | Mental health and crisis intervention | 501(c)(3) | 1992 | $711,552 | $469,622 | 2024-12 |
| South Carolina Respite Coalition | Human services | 501(c)(3) | 2001 | $693,048 | $180,787 | 2026-06 |
| Junior League Columbia Inc | 501(c)(3) | 1945 | $682,462 | $1.8 million | 2025-06 | |
| South Carolina Optometric Physicians Association | 501(c)(6) | 1945 | $665,262 | $749,946 | 2024-12 | |
| Animal Mission | Animal-related | 501(c)(3) | 1991 | $665,186 | $1.2 million | 2026-06 |
| American Council of Engineering Companies of South Carolina | 501(c)(6) | 1976 | $653,447 | $658,893 | 2025-06 | |
| Rho Chapter Kappa Alpha Housing Corporation | Community improvement and capacity building | 501(c)(2) | 2000 | $652,592 | $1.3 million | 2025-12 |
| Scoa Cares Inc | Health care | 501(c)(3) | 2006 | $651,880 | $6.6 million | 2025-12 |
| National Guard Association of South Carolina | Public and societal benefit | 501(c)(19) | 1985 | $648,128 | $1.8 million | 2025-12 |
| Columbia Sailing Club | 501(c)(7) | 1970 | $646,181 | $1.5 million | 2025-12 | |
| New Capernaum Life Services | Community improvement and capacity building | 501(c)(3) | 2020 | $646,000 | $4.9 million | 2025-12 |
| Trustus Inc | Arts, culture and humanities | 501(c)(3) | 1987 | $638,476 | $405,359 | 2025-08 |
| Delta Chapter Alumni House Corporation | Education | 501(c)(7) | 2005 | $628,832 | $622,605 | 2025-12 |
| Most Worshipful Prince Hall Grand Lodge of Free and Accepted Masons | 501(c)(8) | 1974 | $627,655 | $880,480 | 2025-10 | |
| South Carolina Association of Independent Home Schools | 501(c)(3) | 1992 | $626,520 | $128,683 | 2024-12 | |
| Harmony School | 501(c)(3) | 1994 | $622,450 | $497,528 | 2024-12 | |
| South Carolina Wildlife Federation | Animal-related | 501(c)(3) | 1951 | $619,465 | $977,655 | 2025-12 |
| American Institute of Architects SC Chapter | 501(c)(6) | 1971 | $617,921 | $1.7 million | 2024-12 | |
| Family Promise of the Midlands Inc | Human services | 501(c)(3) | 2009 | $613,955 | $913,530 | 2024-12 |
| South Carolina Technical College System Foundation | Education | 501(c)(3) | 1965 | $609,463 | $971,845 | 2025-06 |
| American Legion Auxiliary | 501(c)(19) | 1946 | $606,857 | $163,645 | 2026-06 | |
| Sigma Alpha Epsilon South Carolina Delta Chapter | Recreation and sports | 501(c)(7) | 2018 | $605,994 | $13,333 | 2024-06 |
| South Carolina Health Information Partners | Health care | 501(c)(3) | 2015 | $603,935 | $853,359 | 2025-06 |
| Palmetto State Abortion Fund | Civil rights, social action and advocacy | 501(c)(3) | 2022 | $601,369 | $127,644 | 2025-12 |
| Angels Club | Education | 501(c)(3) | 2019 | $600,797 | $109,810 | 2025-12 |
| South Carolina Association of Veterinarians | 501(c)(6) | 1964 | $599,453 | $875,907 | 2025-12 | |
| Ahepa 284 Inc | Housing and shelter | 501(c)(3) | 1998 | $596,487 | $2.1 million | 2025-06 |
| Robs Ole Place Club | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2023 | $593,690 | $3,735 | 2025-12 |
| A Moment of Hope | Religion-related | 501(c)(3) | 2014 | $589,687 | $192,850 | 2025-12 |
| Daybreak Inc | Civil rights, social action and advocacy | 501(c)(3) | 1985 | $587,907 | $2 million | 2024-12 |
| Fast Forward | Human services | 501(c)(3) | 2005 | $587,142 | $394,121 | 2026-06 |
| Belvedere Early Learning Center Inc | 501(c)(3) | 1986 | $585,979 | $171,107 | 2025-12 | |
| Congaree Vista Guild | Community improvement and capacity building | 501(c)(6) | 2005 | $581,300 | $168,958 | 2025-06 |
| Kappa Alpha Order | 501(c)(7) | 1967 | $576,924 | $30,732 | 2025-06 | |
| Brain Injury Association of South Carolina | Health care | 501(c)(3) | 2001 | $574,057 | $555,881 | 2025-06 |
| Certified Development Corporation of South Carolina | Community improvement and capacity building | 501(c)(3) | 1996 | $569,341 | $1.3 million | 2025-12 |
| Trustees Uw Alida Harper Fowlkes for the Society of the Cincinnati | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1988 | $569,281 | $2.7 million | 2024-12 |
| Grace Community Academy of Columbia Inc | Education | 501(c)(3) | 2025 | $565,885 | $58,716 | 2025-06 |
| South Carolina Council On Economic Education | 501(c)(3) | 1976 | $563,019 | $491,646 | 2025-06 | |
| New Beginnings Family Services Inc | Human services | 501(c)(3) | 2009 | $558,570 | $0 | 2011-06 |
| Richland Library Friends and Foundation | Education | 501(c)(3) | 1984 | $550,627 | $1.7 million | 2025-06 |
| College Panhellenic Association | Recreation and sports | 501(c)(7) | 2021 | $547,250 | $331,682 | 2024-12 |
| American Civil Liberties Union | 501(c)(4) | 1970 | $546,968 | $1.1 million | 2025-03 | |
| Columbia International Festival | Arts, culture and humanities | 501(c)(3) | 2009 | $537,620 | $19,327 | 2025-12 |
| Gamma Phi Beta Sorority Inc | 501(c)(7) | 1959 | $529,149 | $475,830 | 2026-07 | |
| Chi Omega Fraternity | 501(c)(7) | 1940 | $527,579 | $105,381 | 2025-06 | |
| South Carolina Beverage Association | 501(c)(6) | 1943 | $521,189 | $557,915 | 2025-09 | |
| Nurturing Center Inc | Human services | 501(c)(3) | 1989 | $516,831 | $502,894 | 2025-06 |
| Wholespire Inc | Education | 501(c)(3) | 2001 | $516,582 | $78,576 | 2025-12 |
| South Carolina Railroad Museum Inc | 501(c)(3) | 1981 | $515,823 | $708,400 | 2025-12 | |
| International Friendship Ministries | International, foreign affairs and national security | 501(c)(3) | 1983 | $512,648 | $206,992 | 2025-12 |
| Limitless Community Development Corp | Community improvement and capacity building | 501(c)(3) | 2011 | $508,341 | $121,516 | 2025-12 |
| Baptist Healthcare System of South Carolina Inc | Health care | 501(c)(3) | 1946 | $505,234 | $825,948 | 2025-09 |
| Hold Out the Lifeline A Mission To Families Inc | Health care | 501(c)(3) | 2025 | $504,730 | $119,263 | 2024-12 |
| Live Oak Counseling Center | Mental health and crisis intervention | 501(c)(3) | 1992 | $503,715 | $390,778 | 2025-12 |
| South Carolina First Steps To School Readiness Board of Trustees | Education | 501(c)(3) | 2000 | $500,008 | $89,118 | 2025-06 |
| Association of School Business Officials International | 501(c)(3) | 1988 | $497,412 | $289,436 | 2026-03 | |
| South Carolina Workmens Compensation Educational Associati | Education | 501(c)(3) | 2008 | $496,973 | $442,800 | 2025-12 |
| Justice 360 | Civil rights, social action and advocacy | 501(c)(3) | 1989 | $496,928 | $352,221 | 2025-12 |
| Columbia Music Festival Assoc | Arts, culture and humanities | 501(c)(3) | 1938 | $493,905 | $313,728 | 2025-06 |
| Dorn Research Institute | Medical research | 501(c)(3) | 1998 | $487,458 | $1.1 million | 2025-09 |
| James E Clyburn Scholarship and Research Foundation | Education | 501(c)(3) | 1995 | $468,223 | $40,199 | 2025-12 |
| Carolina Wildlife Center | Animal-related | 501(c)(3) | 1991 | $467,859 | $248,665 | 2024-12 |
| Colajazz Foundation | Arts, culture and humanities | 501(c)(3) | 2020 | $464,094 | $262,552 | 2025-12 |
| Everyblackgirl Inc | Education | 501(c)(3) | 2016 | $453,377 | $1.4 million | 2024-12 |
| South Carolina Broadcasters Association | Arts, culture and humanities | 501(c)(6) | 1972 | $451,666 | $950,461 | 2025-12 |
| South Carolina Health Insurance Pool | 501(c)(26) | 1997 | $451,263 | $1.5 million | 2025-12 | |
| Healthy Routines | Education | 501(c)(3) | 2020 | $449,820 | $230,131 | 2025-12 |
| Palmetto Animal Assisted Lifeservices | Human services | 501(c)(3) | 2007 | $447,733 | $982,143 | 2024-12 |
| South Carolina Troopers Association | 501(c)(5) | 1989 | $442,959 | $956,901 | 2025-06 | |
| Stepping Stones Ministry Inc | Employment | 501(c)(3) | 2001 | $442,295 | $1.1 million | 2024-12 |
| South Carolina Police Chiefs Association | 501(c)(6) | 1992 | $441,306 | $77,267 | 2025-12 | |
| Womens Shelter | Mental health and crisis intervention | 501(c)(3) | 1991 | $439,623 | $2.1 million | 2025-12 |
| Nami Mid-Carolina | 501(c)(3) | 1986 | $435,978 | $460,069 | 2024-12 | |
| Columbia Childrens Theatre | Arts, culture and humanities | 501(c)(3) | 2006 | $430,051 | $28,301 | 2025-08 |
| Ahepa 284 II Inc | Housing and shelter | 501(c)(3) | 1999 | $424,565 | $1.7 million | 2025-06 |
| Palmetto Baseball League Inc | Recreation and sports | 501(c)(3) | 1995 | $424,387 | $2.2 million | 2025-12 |
| South Carolina Citizens for Life Inc | 501(c)(3) | 1987 | $419,259 | $526,825 | 2024-12 | |
| Nurses Association of South Carolina | 501(c)(6) | 1969 | $413,114 | $40,867 | 2025-12 | |
| Nurses Association of South Carolina | 501(c)(6) | 1969 | $413,114 | $40,867 | 2025-12 | |
| Pi Kappa Phi Fraternity | Education | 501(c)(7) | 2025 | $411,890 | $15,063 | 2025-06 |
| Prince Hall Grand Chapter Order of the Eastern Stars and Rite of Adop | 501(c)(8) | 1985 | $402,179 | $1.6 million | 2026-06 | |
| Haiti Under God Inc | International, foreign affairs and national security | 501(c)(3) | 2004 | $397,527 | $449,920 | 2025-12 |
| JMH Ministries | Religion-related | 501(c)(3) | 2010 | $394,360 | $216,360 | 2025-12 |
| River Alliance | Environment | 501(c)(3) | 1996 | $393,481 | $2.4 million | 2025-06 |
| Wideman-Davis Dance of New York Inc | Arts, culture and humanities | 501(c)(3) | 2014 | $392,253 | $701,862 | 2025-12 |
| South Carolina Nurserymens Association Inc | 501(c)(5) | 1985 | $389,575 | $554,990 | 2025-06 | |
| Gamma Chi Chapter of the Alpha Epsilon Pi Chapter | Education | 501(c)(7) | 2023 | $388,282 | $7,282 | 2025-12 |
| The South Carolina National Guard Foundation | 501(c)(3) | 1989 | $386,827 | $1.4 million | 2025-12 | |
| South Carolina Information Technology Directors Association | 501(c)(6) | 1985 | $385,539 | $489,810 | 2025-12 | |
| Navigating From Good To Greatfoundation | Community improvement and capacity building | 501(c)(3) | 2007 | $385,399 | $254,305 | 2025-08 |
| Live Oak Place LLC | Housing and shelter | 501(c)(3) | 2019 | $383,248 | $4 million | 2024-09 |
| South Carolina Methodist Conference Credit Union | 501(c)(14) | 1968 | $383,062 | $5.9 million | 2025-12 | |
| Palmetto Association for Children and Families | 501(c)(3) | 1990 | $380,814 | $3.6 million | 2024-12 | |
| South Carolina Association of Alcoholism & Drug Abuse Counselors | Mental health and crisis intervention | 501(c)(3) | 1998 | $380,359 | $515,805 | 2025-06 |
| Midlands Housing Trust Fund | Housing and shelter | 501(c)(3) | 2011 | $378,720 | $3.2 million | 2025-06 |
| One Columbia for Arts and History | Arts, culture and humanities | 501(c)(3) | 2014 | $378,297 | $34,716 | 2025-06 |
| Wegoja Foundation | Education | 501(c)(3) | 2009 | $376,058 | $74,103 | 2025-06 |
| Ann Brodies Carolina Ballet | 501(c)(3) | 1989 | $374,795 | $43,931 | 2025-06 | |
| Soar Columbia | Religion-related | 501(c)(3) | 2017 | $368,773 | $155,095 | 2024-12 |
| South Carolina Law Enforcement Officers Association | 501(c)(6) | 1966 | $368,494 | $52,841 | 2026-06 | |
| Growco Columbia Inc | Community improvement and capacity building | 501(c)(3) | 2019 | $367,881 | $351,146 | 2024-12 |
| Phi Delta Theta Fraternity | 501(c)(7) | 1940 | $367,453 | $4,313 | 2025-06 | |
| Ahepa 284 III Inc | Housing and shelter | 501(c)(3) | 2007 | $364,153 | $3 million | 2025-06 |
| Federation of Families of South Carolina | Mental health and crisis intervention | 501(c)(3) | 2000 | $361,520 | $60,406 | 2023-06 |
| South Carolina Pest Control Association Inc | 501(c)(6) | 1987 | $361,494 | $246,848 | 2026-06 | |
| South Carolina Chiropractors Association | 501(c)(6) | 1964 | $358,236 | $879,459 | 2025-12 | |
| Focused Living Ministries Inc | Religion-related | 501(c)(3) | 1995 | $358,031 | $489,384 | 2024-12 |
| National Retired Military Golf Classic Inc | Recreation and sports | 501(c)(3) | 2014 | $356,327 | $164,514 | 2026-06 |
| Injured Workers Advocates | 501(c)(6) | 1985 | $355,276 | $214,175 | 2025-12 | |
| Palmetto Nuclear Coalition | Environment | 501(c)(4) | 2026 | $354,688 | $124,697 | 2025-12 |
| South Carolina Foundation for Educational Leadership | Education | 501(c)(3) | 1993 | $354,508 | $4.4 million | 2025-06 |
| CL Seven | Human services | 501(c)(3) | 2015 | $350,049 | $80 | 2025-12 |
| Carolina Childrens Home | Human services | 501(c)(3) | 1947 | $347,103 | $5.9 million | 2025-09 |
| South Carolina State Firemens Assoc | Education | 501(c)(3) | 2001 | $343,530 | $790,701 | 2025-09 |
| Good Samaritan Auto Care | Religion-related | 501(c)(3) | 2023 | $343,468 | $171,314 | 2025-12 |
| Ahepa 284 IV Inc | Housing and shelter | 501(c)(3) | 2014 | $341,662 | $3.1 million | 2025-06 |
| 721 Ministries Inc | Religion-related | 501(c)(3) | 2004 | $340,401 | $222,710 | 2024-12 |
| Tri-Vision Housing Corporation | 501(c)(3) | 1986 | $340,115 | $601,084 | 2024-12 | |
| Columbia Hope Inchrist Inc | Religion-related | 501(c)(3) | 1992 | $339,072 | $163,016 | 2025-12 |
| Original Design | Recreation and sports | 501(c)(3) | 2021 | $334,113 | $286,318 | 2025-12 |
| South Carolina Cancer Alliance | 501(c)(3) | 2000 | $332,443 | $344,508 | 2025-06 | |
| Gandy Griffin Post 4262 Veterans of Foreign Wars | Public and societal benefit | 501(c)(19) | 2022 | $329,443 | $1.2 million | 2025-12 |
| South Carolina Restaurant and Lodging Foundation | Education | 501(c)(3) | 2002 | $326,945 | $364,923 | 2024-12 |
| Greater Waverly Foundation Inc | Human services | 501(c)(3) | 2004 | $326,025 | $219,000 | 2024-12 |
| Miss BS Learning Bees | Education | 501(c)(3) | 2014 | $323,039 | $122,759 | 2023-12 |
| South Carolina Association for Educational Technology | 501(c)(3) | 1989 | $322,110 | $344,428 | 2024-12 | |
| American Postal Workers Union | 501(c)(5) | 1973 | $317,492 | $240,917 | 2025-12 | |
| Kappa Sigma Fraternity | 501(c)(7) | 1940 | $316,407 | $3,074 | 2025-05 | |
| South Carolina Association of Governmental Organizations | Community improvement and capacity building | 501(c)(3) | 2004 | $314,958 | $865,707 | 2025-06 |
| Diannes Call | Health care | 501(c)(3) | 2008 | $312,644 | $423,110 | 2025-12 |
| Scottish Rite Foundation of South Carolina Inc | Mutual and membership benefit | 501(c)(3) | 1986 | $312,033 | $2.5 million | 2025-12 |
| Richland County Court Appointed Special Advocates Inc Casa | 501(c)(3) | 1986 | $309,411 | $368,545 | 2025-06 | |
| Richland County Sheriffs Foundation Inc | 501(c)(3) | 1995 | $308,921 | $256,697 | 2025-12 | |
| South Carolina Telecommunications and Broadband Association | 501(c)(6) | 1978 | $308,436 | $346,083 | 2024-12 | |
| Apartment Association of Greater Columbia Inc | 501(c)(6) | 1983 | $307,544 | $208,250 | 2025-12 | |
| Ministry of Outreach To Slavic Tribes Inc | Religion-related | 501(c)(3) | 2002 | $305,719 | $594,217 | 2025-12 |
| Community Wellness Outreach | Mental health and crisis intervention | 501(c)(3) | 2021 | $305,300 | $1,600 | 2026-04 |
| Carolina Therapeutic Riding Inc | Animal-related | 501(c)(3) | 2021 | $304,654 | $983,152 | 2024-12 |
| South Carolina Poultry Federation Inc | Food, agriculture and nutrition | 501(c)(6) | 2024 | $304,194 | $704,576 | 2025-07 |
| The Marionette Theater of South Carolina | 501(c)(3) | 1989 | $302,285 | $139,866 | 2025-06 | |
| SC Progressive Network Education Fund | Education | 501(c)(3) | 1999 | $291,567 | $514,709 | 2024-12 |
| Richland County Bar Association | 501(c)(6) | 1985 | $285,348 | $409,556 | 2024-12 | |
| Rotary International | 501(c)(4) | 1942 | $283,730 | $379,510 | 2025-06 | |
| National Federation of the Blind of South Carolina | Diseases, disorders and medical disciplines | 501(c)(3) | 1970 | $283,721 | $150,857 | 2025-12 |
| National Federation of the Blind of South Carolina | Diseases, disorders and medical disciplines | 501(c)(3) | 1970 | $283,721 | $150,857 | 2025-12 |
| The Esther Jeanette Shumpert Walker Trust | Human services | 501(c)(3) | 1987 | $283,601 | $1.6 million | 2025-12 |
| South Carolina Summer Dance Conservatory | Arts, culture and humanities | 501(c)(3) | 2001 | $281,827 | $14,023 | 2024-12 |
| Killingsworth | 501(c)(3) | 1974 | $280,872 | $155,226 | 2025-12 | |
| Xavier Baez Ministries | Religion-related | 501(c)(3) | 2013 | $278,956 | $153,322 | 2025-12 |
| South Carolina Alliance of Black School Educators | Education | 501(c)(3) | 2003 | $276,857 | $246,564 | 2025-06 |
| Womans Baptist Educational & Missio Nary Convention of South Carolina | 501(c)(3) | 1993 | $275,399 | $166,523 | 2025-12 | |
| Palmetto Agribusiness Council | Food, agriculture and nutrition | 501(c)(6) | 2000 | $275,278 | $425,298 | 2024-12 |
| Midlands Mechanical Apprentice Coalition | Employment | 501(c)(3) | 2023 | $272,001 | $441,117 | 2025-12 |
| South Carolina Insurance Association | 501(c)(6) | 1977 | $271,160 | $397,343 | 2024-12 | |
| Edens Community Enrichment Foundation | Education | 501(c)(3) | 2019 | $270,772 | $301,620 | 2025-12 |
| Saluda Shoals Foundation | Recreation and sports | 501(c)(3) | 1995 | $270,121 | $888,432 | 2025-06 |
| Rainy Day Fund | Crime and legal-related | 501(c)(3) | 2021 | $269,888 | $164,133 | 2025-12 |
| Suzuki Academy of Columbia | Education | 501(c)(3) | 2019 | $267,327 | $104,692 | 2025-05 |
| South Carolina Pride Movement Inc | Arts, culture and humanities | 501(c)(3) | 2018 | $267,166 | $32,838 | 2025-12 |
| Leadership South Carolina | Education | 501(c)(3) | 2004 | $266,266 | $485,524 | 2025-06 |
| South Carolina Press Association | 501(c)(6) | 1972 | $264,250 | $1.1 million | 2025-09 | |
| Cogito Academies | Education | 501(c)(3) | 2024 | $259,415 | $10.6 million | 2025-06 |
| Carolinas Natural Gas Coalition | Environment | 501(c)(6) | 2022 | $258,162 | $107,245 | 2025-06 |
| Carolina Marathon Association Inc | 501(c)(3) | 1994 | $255,036 | $59,939 | 2025-12 | |
| South Carolina Association of Criminal Defense Lawyers | 501(c)(6) | 1994 | $252,748 | $131,475 | 2025-12 | |
| Arts Innovation and Media Middle College | Education | 501(c)(3) | 2025 | $251,300 | $241,638 | 2025-06 |
| Uasc International | Education | 501(c)(3) | 2019 | $250,896 | $4,482 | 2024-12 |
| Palmetto Power Cities | 501(c)(6) | 1987 | $250,860 | $498,527 | 2024-12 | |
| Central Midlands Justice Ministry | Community improvement and capacity building | 501(c)(3) | 2017 | $250,221 | $45,450 | 2025-12 |
| American Legion | 501(c)(19) | 1946 | $250,048 | $3,127 | 2025-12 | |
| Adjutant Generals Corps Regimental Association | Public and societal benefit | 501(c)(3) | 2023 | $249,590 | $331,616 | 2024-12 |
| Masjid Noor Ul Huda | Religion-related | 501(c)(3) | 2005 | $249,036 | $394,622 | 2020-12 |
| Pi Kappa Alpha Fraternity | Education | 501(c)(7) | 1941 | $247,307 | $11,914 | 2024-06 |
| South Carolina Captive Insurance Association Inc | Mutual and membership benefit | 501(c)(6) | 2000 | $247,009 | $419,823 | 2025-12 |
| Jamil Shriners Group Return | 501(c)(10) | 1940 | $242,882 | $284,402 | 2024-12 | |
| South Carolina Speech and Hearing Association | 501(c)(6) | 1980 | $242,203 | $497,429 | 2025-06 | |
| Delta Tau Delta Fraternity | 501(c)(7) | 1940 | $239,413 | $0 | 2025-07 | |
| Dyslexia Reseource Center | Community improvement and capacity building | 501(c)(3) | 2001 | $238,966 | $127,789 | 2025-12 |
| International College Learning Center Association Inc | 501(c)(3) | 1989 | $237,914 | $268,235 | 2024-12 | |
| 701 Center for Contemporary Art | Arts, culture and humanities | 501(c)(3) | 2009 | $237,911 | $137,624 | 2025-06 |
| Ukrainian Patriot Inc | International, foreign affairs and national security | 501(c)(3) | 2022 | $235,004 | $33,804 | 2024-12 |
| Destiny House Transitional Houses and Programs | Housing and shelter | 501(c)(3) | 2022 | $229,012 | $11,045 | 2024-12 |
| Southeast Governmental Fleet Managers Association | Community improvement and capacity building | 501(c)(6) | 2014 | $222,674 | $143,377 | 2025-12 |
| American Federation of Government Employees | 501(c)(5) | 1940 | $222,064 | $572,061 | 2024-12 | |
| Creek at Mungo Park A Non-Profit Corporation | Recreation and sports | 501(c)(7) | 2025 | $221,518 | $20,534 | 2025-12 |
| National African American Rvers | Recreation and sports | 501(c)(7) | 1996 | $220,842 | $368,044 | 2025-08 |
| South Carolina Afterschool Alliance | Education | 501(c)(3) | 2003 | $220,286 | $269,938 | 2024-12 |
| South Carolina Radiation Quality Standards Association | Community improvement and capacity building | 501(c)(3) | 2001 | $218,997 | $611,743 | 2025-12 |
| Bowman Low Rental Housing Co Inc | Housing and shelter | 501(c)(3) | 1995 | $218,411 | $509,283 | 2024-12 |
| Columbia Classical Ballet Co | 501(c)(3) | 1992 | $215,431 | $1,343 | 2025-06 | |
| Brennen Elementary School Parent-Teacher Organization Pto | 501(c)(3) | 1990 | $213,566 | $104,932 | 2025-07 | |
| Artists for Africa | Arts, culture and humanities | 501(c)(3) | 2014 | $212,174 | $82,682 | 2025-12 |
| W L Bonner Bible College | Education | 501(c)(3) | 1999 | $210,576 | $436,389 | 2021-12 |
| The South Carolina Association of Special Purpose Districts | 501(c)(4) | 1989 | $209,245 | $275,158 | 2025-12 | |
| Monday After the Masters Mam Pro-Am Golf Tournament Inc | 501(c)(3) | 1994 | $207,978 | $318,181 | 2025-12 | |
| Dreher High School Athletic Booster Club | 501(c)(3) | 1964 | $207,115 | $196,177 | 2025-06 | |
| Garden Club of South Carolina Inc | Environment | 501(c)(3) | 2011 | $206,880 | $757,052 | 2025-04 |
| Nurses With Purpose Inc | Human services | 501(c)(3) | 2018 | $205,314 | $5,133 | 2025-12 |
| S C Ag-In-The-Classroom Fund | Education | 501(c)(3) | 2000 | $204,787 | $814,416 | 2025-07 |
| Workshop Theatre of South Carolina | Arts, culture and humanities | 501(c)(3) | 1967 | $201,338 | $24,394 | 2025-05 |
| Columbia Parks and Recreation Foundation | Recreation and sports | 501(c)(3) | 2001 | $198,933 | $125,227 | 2025-12 |
| Isonomy Inc | Civil rights, social action and advocacy | 501(c)(3) | 2022 | $198,511 | $2,500 | 2023-12 |
| Harmon Hill Apartments Inc | Housing and shelter | 501(c)(3) | 2001 | $197,797 | $763,693 | 2025-12 |
| South Carolina Alliance for Recovery Residences | Mental health and crisis intervention | 501(c)(3) | 2018 | $197,627 | $143,151 | 2024-12 |
| Central League - SC Amateur Soccer Association | Recreation and sports | 501(c)(3) | 2003 | $196,893 | $492,605 | 2025-05 |
| International Plant Propagators Society Inc Southern Region | 501(c)(5) | 1979 | $195,262 | $174,761 | 2025-06 | |
| Law Enforcement Chaplaincy for South Carolina | Human services | 501(c)(3) | 1998 | $194,936 | $305,381 | 2025-06 |
| Discovery Therapies Inc | Education | 501(c)(3) | 2011 | $193,827 | $4,282 | 2025-05 |
| Gault Grove Apartments Inc | Housing and shelter | 501(c)(3) | 1994 | $193,331 | $396,576 | 2025-12 |
| Christian Study Center at U of SC | Religion-related | 501(c)(3) | 2023 | $193,277 | $82,130 | 2025-12 |
| Brookland Foundtion | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 1997 | $192,551 | $15,379 | 2024-12 |
| Outdoor Advertising Association of SC Inc | Social science | 501(c)(4) | 1999 | $189,690 | $284,413 | 2025-12 |
| Little League Baseball Inc | 501(c)(3) | 1967 | $188,564 | $88,746 | 2025-09 | |
| Sandstone Apartments Inc | Human services | 501(c)(3) | 1996 | $186,486 | $548,160 | 2025-12 |
By cause in Columbia, SC
- Education 310
- Human services 300
- Religion-related 298
- Community improvement and capacity building 165
- Arts, culture and humanities 159
- Youth development 115
- Recreation and sports 97
- Philanthropy, voluntarism and grantmaking foundations 83
- Health care 63
- Public and societal benefit 51
- Housing and shelter 50
- Environment 39
- Mental health and crisis intervention 32
- Mutual and membership benefit 29
- Animal-related 28
- Crime and legal-related 27
- Food, agriculture and nutrition 24
- Civil rights, social action and advocacy 24
- Employment 21
- Diseases, disorders and medical disciplines 21
- International, foreign affairs and national security 17
- Science and technology 17
- Public safety, disaster preparedness and relief 15
- Medical research 9
- Social science 3
Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.