| Presbyterian Communities of South Carolina | 501(c)(3) | 1959 | $87.6 million | $183.7 million | 2025-12 |
| Scbma | 501(c)(3) | 1961 | $31.6 million | $52.3 million | 2025-09 |
| Wateree Community Actions Inc | 501(c)(3) | 2017 | $30.4 million | $14.1 million | 2024-12 |
| South Carolina Youth Advocate Program Inc | 501(c)(3) | 1991 | $26.6 million | $69.6 million | 2025-12 |
| Epworth Childrens Home | 501(c)(3) | 1950 | $22.1 million | $64.5 million | 2025-12 |
| Childrens Trust Fund of South Carolina | 501(c)(3) | 1985 | $21.3 million | $14.5 million | 2025-09 |
| Cooperative Ministry | 501(c)(3) | 1988 | $4.7 million | $3.8 million | 2025-06 |
| Jubilee Academy Inc | 501(c)(3) | 2001 | $4.4 million | $3.9 million | 2024-12 |
| Senior Resources Inc | 501(c)(3) | 1967 | $4.3 million | $6.5 million | 2025-06 |
| Family Connection of South Carolina Inc | 501(c)(3) | 1990 | $3.6 million | $2.7 million | 2025-06 |
| Family Preservation Community Services | 501(c)(3) | 1999 | $2.6 million | $10.8 million | 2025-06 |
| Vital Connections of the Midlands Inc | 501(c)(3) | 2004 | $2.5 million | $1.3 million | 2025-06 |
| North Flint Reinvestment Corporation | 501(c)(3) | 2014 | $2.3 million | $1.8 million | 2025-09 |
| Serve and Connect | 501(c)(3) | 2017 | $2.1 million | $1.2 million | 2025-06 |
| FPCRC Inc | 501(c)(3) | 1988 | $1.8 million | $29.5 million | 2026-04 |
| Reconciliation Ministries SC | 501(c)(3) | 2004 | $1.7 million | $4.9 million | 2024-12 |
| Columbia Urban League Inc | 501(c)(3) | 1970 | $1.7 million | $3.4 million | 2024-12 |
| Ronald McDonald House Charities of Columbia SC | 501(c)(3) | 1982 | $1.5 million | $5.4 million | 2024-12 |
| Home Works of America Inc | 501(c)(3) | 1998 | $1.2 million | $373,870 | 2024-12 |
| Flourishing Families of South Carolina | 501(c)(3) | 2019 | $1.1 million | $345,660 | 2025-10 |
| Kennedys Assistive Living & Educational Facility | 501(c)(3) | 2009 | $913,500 | $52,206 | 2025-12 |
| Hive Community Circle | 501(c)(3) | 2015 | $838,617 | $41,345 | 2025-06 |
| Womens Rights and Empowerment Network | 501(c)(3) | 2016 | $828,443 | $2.2 million | 2025-06 |
| Palmetto Family Council | 501(c)(3) | 1993 | $780,223 | $230,753 | 2025-12 |
| South Carolina Respite Coalition | 501(c)(3) | 2001 | $693,048 | $180,787 | 2026-06 |
| Family Promise of the Midlands Inc | 501(c)(3) | 2009 | $613,955 | $913,530 | 2024-12 |
| Fast Forward | 501(c)(3) | 2005 | $587,142 | $394,121 | 2026-06 |
| New Beginnings Family Services Inc | 501(c)(3) | 2009 | $558,570 | $0 | 2011-06 |
| Nurturing Center Inc | 501(c)(3) | 1989 | $516,831 | $502,894 | 2025-06 |
| Palmetto Animal Assisted Lifeservices | 501(c)(3) | 2007 | $447,733 | $982,143 | 2024-12 |
| CL Seven | 501(c)(3) | 2015 | $350,049 | $80 | 2025-12 |
| Carolina Childrens Home | 501(c)(3) | 1947 | $347,103 | $5.9 million | 2025-09 |
| Greater Waverly Foundation Inc | 501(c)(3) | 2004 | $326,025 | $219,000 | 2024-12 |
| The Esther Jeanette Shumpert Walker Trust | 501(c)(3) | 1987 | $283,601 | $1.6 million | 2025-12 |
| Nurses With Purpose Inc | 501(c)(3) | 2018 | $205,314 | $5,133 | 2025-12 |
| Law Enforcement Chaplaincy for South Carolina | 501(c)(3) | 1998 | $194,936 | $305,381 | 2025-06 |
| Sandstone Apartments Inc | 501(c)(3) | 1996 | $186,486 | $548,160 | 2025-12 |
| Lradac Foundation | 501(c)(3) | 2012 | $181,585 | $77,014 | 2025-06 |
| Chestnut Ferry Court Incorporated | 501(c)(3) | 1995 | $171,850 | $723,329 | 2024-12 |
| Fortitude Foundation Inc | 501(c)(3) | 2011 | $154,517 | $1 | 2025-06 |
| Trustees Education Network Inc | 501(c)(3) | 1999 | $142,615 | $154,426 | 2025-09 |
| Ems Closet | 501(c)(3) | 2022 | $116,122 | $82,054 | 2024-12 |
| Omega Men of Columbia South Carolina Inc | 501(c)(3) | 2012 | $109,329 | $100,803 | 2023-10 |
| Greater South Farrow Road Community Development Foundation | 501(c)(3) | 2015 | $107,264 | $82,284 | 2023-12 |
| The South Carolina Juneteenth Freedom Festival | 501(c)(3) | 2025 | $101,757 | $15,758 | 2024-12 |
| Wiley Kennedy Foundation | 501(c)(3) | 2014 | $98,905 | $41,906 | 2025-12 |
| South Carolina Spinal Cord Injury Association | 501(c)(3) | 1994 | $97,339 | $27,736 | 2025-12 |
| Beta Chi Sigma-Phi Beta Sigma | 501(c)(3) | 2014 | $88,823 | $92,400 | 2025-12 |
| Tri-Community Center Incorporated | 501(c)(3) | 2019 | $81,500 | $96,594 | 2024-12 |
| Homemisc | 501(c)(3) | 2023 | $81,233 | $94,310 | 2023-12 |
| Trinity Educational Community Center | 501(c)(3) | 2016 | $75,791 | $40,986 | 2025-12 |
| South Carolina Pest Management Charitable Foundation | 501(c)(3) | 2015 | $75,768 | $93,647 | 2026-06 |
| Pandemic Patients | 501(c)(3) | 2021 | $62,724 | $16,167 | 2024-12 |
| Straight Road International | 501(c)(3) | 2012 | $58,011 | $18,404 | 2025-12 |
| Joseph Outreach | 501(c)(3) | 2011 | $55,490 | $96,660 | 2025-07 |
| South Carolina Black Pride Inc | 501(c)(3) | 2022 | $49,076 | $26,071 | 2025-12 |
| Alala Cancer Society | 501(c)(3) | 2008 | $48,154 | $59,941 | 2024-06 |
| Champions for Children | 501(c)(3) | 2022 | $41,570 | $13,455 | 2025-12 |
| Columbia Bethlehem Community Center | 501(c)(3) | 1973 | $40,843 | $1 | 2025-12 |
| Nactt Foundation | 501(c)(3) | 2006 | $39,444 | $213,816 | 2025-12 |
| Palmetto Cycling Coalition | 501(c)(3) | 1998 | $39,090 | $32,873 | 2025-12 |
| General Federation of Womens Clubs of South Carolina | 501(c)(3) | 1962 | $34,232 | $288,055 | 2025-05 |
| Fisher House of Columbia SC Inc | 501(c)(3) | 2017 | $29,221 | $162,118 | 2025-12 |
| Midlands Holy Family Fund Inc | 501(c)(3) | 2004 | $27,412 | $2,614 | 2025-05 |
| North Columbia Community Enrichment Foundation | 501(c)(3) | 2012 | $19,805 | $77,481 | 2025-12 |
| Coats for Kindness Inc | 501(c)(3) | 2011 | $11,526 | $26,685 | 2025-12 |
| Joyful Justice | 501(c)(3) | 2023 | $6,809 | $3,061 | 2024-12 |
| Gamecock Foundation | 501(c)(3) | 2015 | $6,313 | $13,734 | 2025-12 |
| Pearls Columbia | 501(c)(3) | 2016 | $6,282 | $11,199 | 2025-12 |
| Metro City Corvette Club Outreach | 501(c)(3) | 2024 | $3,000 | $1,195 | 2025-12 |
| Sisters Empowering Each Other | 501(c)(3) | 2019 | $2,637 | $909 | 2025-12 |
| Dress for Success Columbia | 501(c)(3) | 2014 | $500 | $211 | 2024-12 |
| Friends of Epworth | 501(c)(3) | 2013 | $433 | $133,726 | 2025-12 |
| Honorable Reverend Clementa C Pinckney Foundation | 501(c)(3) | 2015 | $111 | $1.1 million | 2024-12 |
| 2reach | 501(c)(3) | 2026 | | | |
| A Heart To Give | 501(c)(3) | 2025 | | | |
| Acc Empowerment CDC Inc | 501(c)(3) | 2026 | | | |
| Adap Enterprises Inc | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Adodi Southern Region | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| All About Jesus Church of the Living God | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Allies Armies 2ND Chance | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| American Legion Auxiliary Post 215 | 501(c)(19) | 2018 | $0 | $0 | 2024-06 |
| Anchor Family and Community Services | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Annie Mae Foundation | 501(c)(3) | 2025 | | | |
| Antioch Senior Center | 501(c)(3) | 2025 | | | |
| Apert International Inc | 501(c)(3) | 2000 | $0 | $0 | 2025-12 |
| Appointed Time Family Services | 501(c)(3) | 2023 | $0 | $1 | 2025-12 |
| Arthur of Love Charitable Foundation | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Ausome Fathers Incorporated | 501(c)(3) | 2024 | $0 | $1 | 2025-07 |
| Autistic Artistry Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| BLK Maternal Health Collective | 501(c)(3) | 2025 | | | |
| Barron Community Foundation | 501(c)(3) | 2017 | $0 | $0 | 2023-12 |
| Beamer Family Foundation | 501(c)(3) | 2021 | | $48,558 | 2025-12 |
| Beating All Odds | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Beauty Beyond the Mirror Project | 501(c)(3) | 2019 | $0 | $1 | 2024-12 |
| Bee N Courgaged Inc | 501(c)(3) | 2026 | | | |
| Birthright of Columbia Inc | 501(c)(3) | 2026 | | $2.4 million | 2025-12 |
| Blankets Around the World | 501(c)(3) | 2025 | | | |
| Blessed Smiles | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Both Sides of the Coin Initiative | 501(c)(3) | 2025 | | | |
| Bread of Heaven Missions | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Bridge Build Become | 501(c)(3) | 2026 | | | |
| C and K Gifts of Love | 501(c)(3) | 2025 | | | |
| CHMPSC Helpingvets2day Inc | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Captains Hope Inc | 501(c)(3) | 2019 | $0 | $0 | 2024-06 |
| Center for God Peace & Love | 501(c)(3) | 2022 | $0 | $0 | 2024-08 |
| Center of Holistic Development Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Change My Life Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Chapter One | 501(c)(3) | 2024 | $0 | $0 | 2024-03 |
| Childrens Alliance of North Columbia | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Chosen By U Faith & Wellness Foundation | 501(c)(3) | 2025 | | | |
| Christ Tyt Outreach | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
| Cocoa Collab | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Colvin Family Foundation | 501(c)(3) | 2022 | | $868,988 | 2025-12 |
| Community Impact Initiatives | 501(c)(3) | 2026 | | | |
| Community Vision Strategies | 501(c)(3) | 2025 | | | |
| Cornell Ray Jones Ministries Inc | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Cotton Patch Educational Foundation Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Deonka Deidra Drayton Foundation | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Dream Makers of SC | 501(c)(3) | 2025 | | $1 | 2025-12 |
| E Burden Ministries | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Ears for the Elderly and Children Concerns | 501(c)(3) | 2015 | $0 | $0 | 2024-12 |
| Elt Ventures | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Emmas Diapers Boutique | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Empowering Lives Foundation | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Energe Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-10 |
| Eneslies John Foundation Inc | 501(c)(3) | 2019 | $0 | $0 | 2023-12 |
| Everlight Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| F8it Ministries | 501(c)(3) | 2020 | $0 | $0 | 2023-12 |
| Faith and Blessings Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Family Productions Foundation Inc | 501(c)(3) | 2024 | | | |
| Feed My Sheep Movement and Ministry | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Feed the Streetz | 501(c)(3) | 2025 | | | |
| Fidelity Outreach Ministry | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| First Kids Academy | 501(c)(3) | 2026 | | | |
| Fitzgeralds Legacy Foundation | 501(c)(3) | 2025 | | | |
| Flo Cares Foundation | 501(c)(3) | 2024 | | $4,981 | 2024-12 |
| Forward Horizon Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Forward Progression Mentor - Apprenticeship Program | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Foster the Bear Foundation | 501(c)(3) | 2026 | | | |
| Fostering Joy | 501(c)(3) | 2024 | | | |
| Free To Be Me Naomi R Seabrook Cancer Foundation | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| From Struggle To Strength | 501(c)(3) | 2021 | $0 | $0 | 2023-12 |
| Front Porch Swing | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Gift of Words Inc | 501(c)(3) | 2023 | $0 | $0 | 2026-06 |
| Global Alliance | 501(c)(3) | 2010 | $0 | $0 | 2025-12 |
| Gods Plan Restoration Home | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Greater Columbia Disabilities Foundation | 501(c)(3) | 2002 | $0 | $0 | 2025-06 |
| Growing Hearts Social Support Incor Porated | 501(c)(3) | 2026 | | | |
| Hands Helping Sister Care | 501(c)(3) | 2026 | | | |
| Healing Oak Empowerment Center Inc | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Helping Hands Outreach and Missions Organization | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Helping Hands of Columbia | 501(c)(3) | 2023 | | | |
| Higgins Mentoring Program | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| His Way Deliverance Ministries | 501(c)(3) | 2025 | | | |
| Hohm Institute | 501(c)(3) | 2026 | | | |
| Honey Beehavior Foundation | 501(c)(3) | 2026 | | | |
| Hope for Life Foundation | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Hopewood Haven Ministries Inc | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| Hyman JNR Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| I Am Beyoutfull Foundation | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Icare Non Profit Organization Inc | 501(c)(3) | 2026 | | | |
| Impact Change Foundation | 501(c)(3) | 2011 | $0 | $0 | 2025-12 |
| Inclusive Early Childcare | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Inspire 365 Foundation | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Integral Awareness | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Iola D Foundation | 501(c)(3) | 2024 | | | |
| Irmo Outreach Committee Inc | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| It Takes Heart Foundation | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| J&GKINLOCH Family Care Services | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Jab Foundation | 501(c)(3) | 2025 | | | |
| Jannie R Jackson Womens Center | 501(c)(3) | 2010 | $0 | $0 | 2025-12 |
| Jayln Rachel Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-03 |
| Just Because We Care | 501(c)(3) | 2025 | | | |
| Kickin It With Dads | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Kids Land Extened Stay Foundation | 501(c)(3) | 2026 | | | |
| Kindred Hearts South Carolina | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Kingdom Connect Ministries | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Kingdom K E Y S | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Kingdom Way for Life Inc | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Know More Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| La Fuente de Ayuda | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Lady K Ministries | 501(c)(3) | 2024 | | | |
| Latoya Helping Hands Incorporated | 501(c)(3) | 2021 | $0 | $0 | 2023-12 |
| Legion City Generals | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Let Me Be Me Foundation | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Life Destiny Community Development Corporation | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Lifegivers Co | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Little Party People Foundation Charity Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Longcreek Community Outreach | 501(c)(3) | 2025 | | | |
| Lotus Heart SC | 501(c)(3) | 2026 | | | |
| Matthew J Perry Black Law Students Association | 501(c)(3) | 2024 | $0 | $0 | 2025-05 |
| Mending Broken Hearts Inc | 501(c)(3) | 2020 | $0 | $0 | 2026-06 |
| Mentoring Future Diamond Leaders | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Midlands Area Consortium for the Homeless | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| Midlands Educational Economic Empowerment Center | 501(c)(3) | 2011 | $0 | $0 | 2025-12 |
| Mind Matters | 501(c)(3) | 2014 | $0 | $0 | 2024-12 |
| Minority Speaks | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Miracles in the Midlands | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Mirandas Senior Resource Center | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Mommie & Me Essential | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Mommys Hood Community Wellness Fund Inc | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Mothering Me Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Move By Faith | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Mufeed | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Mydd Foundataion | 501(c)(3) | 2026 | | | |
| Myles Wood Community Care Foundatio N | 501(c)(3) | 2026 | | | |
| Nail Tech Trade School | 501(c)(3) | 2025 | | | |
| Nca Community Development Center Inc | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| New Samaritan Foundation | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| North East Columbia Empowerment Coalition | 501(c)(3) | 2022 | $0 | $0 | 2025-08 |
| North Monticello Community Outreach | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Old Bluff Road Community Outreach Center | 501(c)(3) | 2025 | | | |
| Orangeburg District Empowerment Services | 501(c)(3) | 2020 | $0 | $0 | 2023-12 |
| Our House Resource Center | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Our Refuge Ninety-One | 501(c)(3) | 2023 | | $2,975 | 2024-12 |
| P R E S E N T Visions | 501(c)(3) | 2024 | | | |
| Parent Voices for Safe Communities-Pvsc | 501(c)(3) | 2025 | | | |
| Partnership Initiatives in Education | 501(c)(3) | 2020 | $0 | $250,000 | 2025-07 |
| Pathways To Empowerment | 501(c)(3) | 2023 | $0 | $0 | 2026-01 |
| Pathways To Promise Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Pencal Mentoring Program | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Pieces- A Soulful Journey With Alopecia | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Plug Network | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Positively Influencing the Community With Heart | 501(c)(3) | 2018 | $0 | $0 | 2023-12 |
| Poston Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Power in Changing | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Praise and Deliverance Apostolic Church | 501(c)(3) | 2024 | | | |
| Prayer Warriors United Ministries International | 501(c)(3) | 2016 | $0 | $0 | 2026-06 |
| Prison To Prospering | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Project Aspiration Foundation | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Project Hope-Helping Others Progress Everyday | 501(c)(3) | 2022 | $0 | $0 | 2025-07 |
| Project Nas Community Development Corporation | 501(c)(3) | 2014 | $0 | $0 | 2024-12 |
| Project PLQ Inc | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Rare Leaders | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Re-Discover Me Women Initiative | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Releasing Ashes for Beauty | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Renew Her | 501(c)(3) | 2024 | | | |
| Rhema Restoration Community Development Corporation Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Richard Evans Foundation | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Richland County Foster Parent Association | 501(c)(3) | 2019 | $0 | $0 | 2023-12 |
| Rio Chiquito Mission Network | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Rose Leaf Foundation | 501(c)(3) | 2019 | $0 | $0 | 2026-03 |
| Rotary Club of Lake Murray-Irmo Foundation | 501(c)(3) | 2010 | $0 | $0 | 2025-06 |
| S C Assist | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| SC First | 501(c)(3) | 2026 | | | |
| SC Independent Living Council | 501(c)(3) | 2002 | $0 | $0 | 2025-09 |
| Scrub Life Cares | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Second Hope | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Sewaly Designz Academy Community Development Group | 501(c)(3) | 2024 | | $1 | 2025-12 |
| She Can She Will Global Connect | 501(c)(3) | 2023 | | | |
| Sherwood Forest Neighborhood Association | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Shevolve | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Show Them We Care Foundation | 501(c)(3) | 2003 | $0 | $0 | 2024-12 |
| Sisters Encouraging Sisters Ministries | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Sisters of Mercy CDC | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Skibridge | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Small Ijose Swanier Foundation Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Solomons Heart Inc | 501(c)(3) | 2024 | | | |
| South Carolina Crime Victims Council | 501(c)(3) | 2009 | $0 | $0 | 2026-06 |
| South Carolina Dental Relief Fund Inc | 501(c)(3) | 2014 | $0 | $0 | 2026-06 |
| South Carolina Youth Workers Association | 501(c)(3) | 1995 | $0 | $0 | 2025-12 |
| Southcarolina Cap Directors Association Inc | 501(c)(3) | 2024 | | | |
| Spreadjoy | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Standing Man Youth Mentorship | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Strategic Journeys Inc | 501(c)(3) | 2014 | $0 | $0 | 2024-12 |
| Streets 2 Stability | 501(c)(3) | 2026 | | | |
| Sundry Academy | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Support Our Seniors | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Sword of Spirit Outreach Inc | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| T&T Project | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Tamb Fitness Foundation | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Teen Spirit Forum of the Midlands | 501(c)(3) | 2026 | | | |
| The Bloom Foundation Inc | 501(c)(3) | 2025 | | | |
| The Learning Garden Child Developme NT Center | 501(c)(3) | 2026 | | | |
| The Palmetto School of Protocol Inc | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| The Patricia McKinney Foundation | 501(c)(3) | 2013 | | $58,490 | 2024-12 |
| The Ram Foundation | 501(c)(3) | 2009 | $0 | $0 | 2025-12 |
| They Are Not Coming | 501(c)(3) | 2026 | | | |
| Thompson Ministerial & Professional Services Community Development GR | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Together We Heal | 501(c)(3) | 2025 | | | |
| Transformation Empowerment Center Inc | 501(c)(3) | 2024 | | | |
| Transitional Treasures Foundation | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Tri-Mark Development Corporation | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Unapologetically Embracing Autism | 501(c)(3) | 2024 | $0 | $0 | 2023-12 |
| Unity Adult Center Foundation | 501(c)(3) | 2026 | | | |
| Veterans America | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Veterans Information Workshop | 501(c)(3) | 2014 | $0 | $0 | 2024-12 |
| Vibe and Connect | 501(c)(3) | 2026 | | | |
| Visa Now Foundation Incorporation | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Visions of Women | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Washington Brothers Charities | 501(c)(3) | 2026 | | | |
| Way Ministries 14 6 | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Weaving Hope Today 4 Tomorrow | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Widows in Need | 501(c)(3) | 2012 | $0 | $0 | 2024-12 |
| Widows of Opportunity | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| Wisdom Center | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| World of New Hope Inc | 501(c)(3) | 2022 | | $1 | 2024-10 |
| Yellow Tea Rose Foundation | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Zion Community Foundation | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |