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Data / Nonprofits / South Carolina / Seneca

Nonprofits in Seneca, SC: 228 registered with the IRS

228 nonprofits are registered with the IRS in Seneca, SC, 192 of them 501(c)(3) charities; the 61 that report revenue took in $37.7 million. The largest by revenue: Rosa Clark Medical Center ($5.1 million), Foothills Area YMCA ($4.2 million), Oconee Memorial Hospital Foundation Inc ($3.7 million). Most common causes: religion-related (28), education (18), human services (14).

SpecStream is the live web data engine for teams and agents. It reads the IRS register of exempt organizations as the IRS updates it, and this page is that reading. Ask for the nonprofits you need by place, cause and size, with their latest Form 990 figures and websites, and they arrive in your sheet, CRM, Slack or agent.

Every organization, largest by revenue first

OrganizationCategoryTypeSinceRevenueAssetsFiling
Rosa Clark Medical Center501(c)(3)1991$5.1 million$6.6 million2024-12
Foothills Area YMCAHuman services501(c)(3)1992$4.2 million$23.4 million2025-12
Oconee Memorial Hospital Foundation IncHealth care501(c)(3)2002$3.7 million$18.5 million2025-09
Oconee Medical HoldingHealth care501(c)(3)1956$2.6 million$39.9 million2025-09
Golden Corner Food PantryHuman services501(c)(3)1986$2.4 million$1.8 million2025-12
Habitat for Humanity International Inc501(c)(3)1987$2.3 million$5.1 million2025-06
Oconee County Humane Society IncAnimal-related501(c)(3)2002$1.3 million$1.8 million2025-06
Collins Home Family Ministries501(c)(3)1981$1.3 million$3.2 million2025-12
Ripple of One IncEducation501(c)(3)2011$1.2 million$2.2 million2025-12
Oconee County Country Club501(c)(7)1995$1.2 million$464,1852025-12
Oconee Christian AcademyEducation501(c)(3)1995$1.2 million$3.2 million2025-06
Seneca Facilities CorporationCommunity improvement and capacity building501(c)(3)2014$1.1 million$10.2 million2025-06
Foothills Care Center IncHealth care501(c)(3)1993$823,544$936,9112025-12
United Way of Oconee County IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)1967$784,810$760,9152025-06
The Foothills Agricultural Resources and Marketing CenterEducation501(c)(3)2011$683,308$1.4 million2024-12
Wild Hearts Equine Therapeutic Center IncHealth care501(c)(3)2016$637,797$840,7552025-06
Our Daily RestHousing and shelter501(c)(3)2006$537,654$872,5582024-12
Clemson Area Soccer Club IncRecreation and sports501(c)(3)2001$496,720$150,5492025-12
Oconee Alliance IncCommunity improvement and capacity building501(c)(6)2007$486,890$850,2232025-12
The Vimm FND World Missions Dept Church of God Internatl HeadqtersInternational, foreign affairs and national security501(c)(3)1989$393,318$407,2792025-06
Upstate Institute of Youth ProgramsincYouth development501(c)(3)2007$384,505$87,1642025-12
The Nola NetworkYouth development501(c)(3)2020$351,000$217,1072025-06
National High School Strength Coaches Association501(c)(3)2021$348,662$244,3892023-12
Seneca Improvements CorporationCommunity improvement and capacity building501(c)(3)2017$283,623$6.8 million2025-06
Greater Oconee County Chamber of Commerce501(c)(6)1966$266,845$118,1582025-12
Hope Universal IncReligion-related501(c)(3)2003$239,036$82,0182025-12
The Keowee Sailing Club Inc501(c)(7)1989$236,212$1.1 million2024-12
Lake Keowee Source Water Protection TeamEnvironment501(c)(3)2017$212,782$463,9572025-12
Our Daily BreadFood, agriculture and nutrition501(c)(3)1997$202,910$1 million2024-12
CFK IncHuman services501(c)(3)2018$197,621$319,1362025-12
Soul of PalestineHuman services501(c)(3)2024$195,996$16,8582025-08
Clemson University Flying Club Inc501(c)(3)1994$194,027$382,9602025-12
Miss Dixies Kitten RescueAnimal-related501(c)(3)2019$160,281$128,1652024-12
Shade Tree MinistriesReligion-related501(c)(3)2014$154,789$155,9822025-12
Frontline USAPublic and societal benefit501(c)(3)2019$147,660$46,5692025-12
Grace Independent Bible Missions IncReligion-related501(c)(3)2017$129,163$27,3462024-12
Win Today FoundationHuman services501(c)(3)2023$124,777$157,6792025-12
Blue Ridge Community CenterYouth development501(c)(3)2016$123,475$68,8792025-12
Corinth-Shiloh Volunteer Fire DeptPublic safety, disaster preparedness and relief501(c)(3)2012$121,270$1 million2025-12
Oconee Community Theater IncArts, culture and humanities501(c)(3)1979$97,448$497,4882024-06
Appa-Association of Higher Education Facilities OfficersCommunity improvement and capacity building501(c)(3)1977$97,147$153,0732025-03
Keowee Ebenezer Fire DepartmentPublic safety, disaster preparedness and relief501(c)(3)2016$94,760$375,6482025-12
Arc of Oconee County Inc501(c)(3)1968$89,929$973,2752025-06
Oconee United MinistriesHuman services501(c)(3)2010$89,562$36,8442025-12
Delta Tau Delta Fraternity501(c)(7)1940$80,778$20,9412025-07
Ride To Work Ministry Nonprofit IncPublic and societal benefit501(c)(3)2017$80,603$112,8932025-12
South Carolina Farm Bureau Association501(c)(5)1973$74,566$357,6002024-12
Foothills Conservatory for the Performing ArtsArts, culture and humanities501(c)(3)2004$72,767$90,0362023-12
Knights of Columbus501(c)(8)1940$70,446$74,2332025-06
Blue Ridge Arts CouncilArts, culture and humanities501(c)(3)1974$68,253$222,0592025-06
Unitsusa Org IncHealth care501(c)(3)2015$64,648$6,1882025-12
Crossroads Animal RescueAnimal-related501(c)(3)2014$50,427$1852025-12
Lachlans Hope IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2015$38,294$151,8732024-12
Tri County Entrepreneurial Development CenterCommunity improvement and capacity building501(c)(3)2012$35,398$361,6132026-06
American Legion501(c)(19)1946$27,429$69,7442026-06
Jet Wrestling ClubRecreation and sports501(c)(3)2017$26,483$22,9032024-12
Northside Elementary School Parent Teacher CommitteeEducation501(c)(3)2014$18,970$18,5712025-06
Animal Rescue Fund of South CarolinaAnimal-related501(c)(3)2004$18,563$87,7622024-12
Advocates for Quality DevelopmentincEnvironment501(c)(4)2007$15,876$79,0192025-12
Rotary International501(c)(4)1942$14,051$9,8242025-06
Home Builders Association of Oconee County501(c)(6)1977$12,613$62,0392024-12
A Call To Action OconeeCrime and legal-related501(c)(3)2016$0$02025-12
Ancient Free Masons of South Carolina501(c)(10)1940$0$02025-12
Asa Hoshi FoundationPublic and societal benefit501(c)(3)2026
Atlanta CollectiveReligion-related501(c)(3)2021$0$02025-12
BabyreadEducation501(c)(3)2014$0$02025-12
Back 9 Ministries IncReligion-related501(c)(3)2014$0$02025-12
Band of StarsMutual and membership benefit501(c)(8)2017$0$02025-12
Bayshore Association Inc501(c)(3)1973$0$02026-04
Benevolent & Protective Order of Elks of the USA501(c)(8)1951$0$02025-03
Better Day Bear & FriendsHuman services501(c)(3)2026$0$02025-12
Blue Ridge Community FellowshipReligion-related501(c)(3)2025
Blue Ridge Junior Golf ProgramRecreation and sports501(c)(3)2014$0$02025-06
Blue Ridge MountaineersRecreation and sports501(c)(3)2024
Blue Ridge Volleyball ClubRecreation and sports501(c)(7)2020$0$02023-12
Bounty Land Baptist Church501(c)(3)19642013-12
Boyd Hope for Special Needs TrustHuman services501(c)(3)2001$559,2942025-12
C L Grant ScholarshipEducation501(c)(3)2026$0$02025-12
Camp Infinity IncReligion-related501(c)(3)2010$0$02025-12
Care Thru Cars IncPublic safety, disaster preparedness and relief501(c)(3)2025$0$02025-12
Caroline Grace FoundationHuman services501(c)(3)2022$0$02023-12
Celebrate Christmas With A Hero IncHuman services501(c)(3)2009$0$02025-12
Chaos Athletics LLCRecreation and sports501(c)(3)2025
Chi Alpha Clemson501(c)(3)1964
Chi Phi Fraternity Inc501(c)(7)1972$0$02025-06
Chi Phi Fraternity Inc501(c)(7)1972$0$02024-12
Church of God of Prophecy501(c)(3)1969
Church of God of Prophecy Bible Place501(c)(3)1969
Church of God of Prophecy Bible Place501(c)(3)1969
Church of the Ascension501(c)(3)1971
Cimba ItalyEducation501(c)(3)2026
Clemson Area International Freindship501(c)(4)1983$0$02025-12
Club Elegant FoundationHuman services501(c)(3)2019$0$02025-12
Common Ground Community Church501(c)(3)1970
Community Tree Center IncMental health and crisis intervention501(c)(3)2020$0$02025-12
Corinth Baptist Church501(c)(3)1964
Cross Roads Baptist Church501(c)(3)1964
Crossgate Church501(c)(3)1974
Crossroads Fire Dept IncPublic safety, disaster preparedness and relief501(c)(3)2025
Davis Creek Baptist Church501(c)(3)1964
Delta Zeta Sorority501(c)(7)1970$0$02025-06
Destiny Christian Center International IncorporatedReligion-related501(c)(3)2008
Disabled American Veterans Auxiliary Inc501(c)(4)1973$0$02025-06
Doyle and Judith Carr FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2004$233,3672025-12
DucksrowEducation501(c)(3)2024$0$02025-09
Eternal Shepherd Lutheran Church501(c)(3)1941
Fiarc MinistriesReligion-related501(c)(3)2023
Foothills Community Church501(c)(3)1964
Friends of the Oconee County Guardian Ad Litem ProgramCrime and legal-related501(c)(3)1998$0$02025-12
Full Gospel Temple Incorporated501(c)(3)1970
Future Farmers of America and Its State Associations & Local Chapter501(c)(3)1945
General Federation of Womens Clubs of South Carolina501(c)(3)1962$0$02023-04
Giant Slayer MinistriesReligion-related501(c)(3)2022$0$02026-04
Golden Corner Respite Care ProgramDiseases, disorders and medical disciplines501(c)(3)2016$0$02024-12
Gospel for Ethiopia IncReligion-related501(c)(3)2010$0$02025-12
Grace Baptist Church501(c)(3)1964
Grace Family Church501(c)(3)1992
Greater Oconee County Chamber of Commerce FoundationEducation501(c)(3)2018$0$02025-12
Guardians for the GuardiansAnimal-related501(c)(3)2024$0$02025-12
Heart Land Baptist Church Inc501(c)(3)1964
Hepsibah Baptist Church501(c)(3)1964
Hopewell Baptist Church501(c)(3)1964
Hosanna Christian MinistriesReligion-related501(c)(3)1992
International Association of Lions Clubs501(c)(4)1957$0$02024-06
Joann Johnson in the GapFood, agriculture and nutrition501(c)(3)2023$0$02024-12
Keep Oconee Beautiful Association IncEnvironment501(c)(3)2000$0$02025-12
Kingdom Glory Church IncReligion-related501(c)(3)2012
Laity-Alive & ServingReligion-related501(c)(3)1985$0$02025-12
Lake and Mountain Quilters GuildArts, culture and humanities501(c)(3)1990$0$02025-12
Lakeview Mission501(c)(3)1976
Life Spring International IncReligion-related501(c)(3)2020$0$02025-12
Lifepoint Church of Oconee501(c)(3)1964
Living Word Ministries Incorporated501(c)(3)1987
Lydia Baptist Church501(c)(3)1964
Maranatha Baptist Church501(c)(3)1964
Marine Corps League501(c)(4)1946$0$02026-06
Men of the Round Table UsReligion-related501(c)(3)2026
Metal in Motion - First Robotics Competition Team 343Education501(c)(3)2019$0$02026-05
Modern Woodmen of America501(c)(8)1961$0$02025-12
Modern Woodmen of America501(c)(8)1961$0$02025-12
Mountain Lakes Community AssociationHousing and shelter501(c)(4)2013$0$02025-12
Mustard Seed Reading Academy IncEducation501(c)(3)2025
National Society Colonel Dames XVII Century501(c)(3)1967$0$02025-12
National Society of the Daughters of the American Revolution501(c)(3)1949$0$02025-12
New Beginning Outreach Baptist Church IncReligion-related501(c)(3)2024
New Hope Baptist Church501(c)(3)19642012-12
New Life Christian Fellowship Seneca501(c)(3)1992
Newcomer Club of the FoothillsRecreation and sports501(c)(7)2010$0$02025-07
Newry Church of God501(c)(3)1972
Northside Elementary Chapter of All Pro DadYouth development501(c)(3)2024$0$02024-12
Nutifafa ShelterHealth care501(c)(3)2020$0$02026-05
Oconee Animal Rescue IncAnimal-related501(c)(3)2011$0$02025-12
Oconee Bible StudyReligion-related501(c)(3)2014$0$02023-06
Oconee Conservatory of Fine ArtsEducation501(c)(3)2005$0$02025-12
Oconee County Chaplains Association501(c)(3)1969$0$02025-12
Oconee Dive & Special Rescue Squad IncPublic safety, disaster preparedness and relief501(c)(3)2006$0$02025-12
Oconee Dive Team IncPublic safety, disaster preparedness and relief501(c)(3)2015$0$02025-12
Oconee Farm FoundationFood, agriculture and nutrition501(c)(3)2025$0$02025-12
Oconee Federal Charitable Foundation IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2013$1.3 million2025-12
Oconee Food CouncilFood, agriculture and nutrition501(c)(3)2023$0$02024-12
Oconee Hazmat Team IncPublic safety, disaster preparedness and relief501(c)(3)2019$0$02025-12
Oconee Presbyterian Church501(c)(3)1967
Oconee Presbyterian ChurchReligion-related501(c)(3)2025
One Community ChurchReligion-related501(c)(3)2013
Order of the Eastern Star of South Carolina501(c)(8)1972$0$02025-12
Order of the Eastern Star of South Carolina 5 Seneca501(c)(8)1972$0$02025-12
Parkway Baptist Church501(c)(3)1964
Phenomenal Women of A New Generatio N IncHuman services501(c)(3)2026$0$02021-12
Phi Delta Theta SC Gamma Alumni Association IncEducation501(c)(7)2022$0$02025-12
Pi Kappa Alpha Fraternity501(c)(7)1941$0$02025-12
Psi Upsilon Fraternity501(c)(7)1945$0$02025-12
Puzzle Piece Foundation IncDiseases, disorders and medical disciplines501(c)(3)2014$22,1662024-12
Quality Deer Management AssociationAnimal-related501(c)(3)2002
Ravenel Parent Teacher OrganizationEducation501(c)(3)2010$0$02026-06
Reedy Fork Baptist Church501(c)(3)1964
Return Baptist Church501(c)(3)1964
Ridge Family FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2017$171,0702025-12
River of Life Community ChurchReligion-related501(c)(3)2015
Rock the RanchArts, culture and humanities501(c)(3)2016$0$02024-12
Roger Duncan Ministries IncReligion-related501(c)(3)2025$0$02025-12
Rotary International501(c)(4)1966$0$02026-06
SaeRecreation and sports501(c)(7)2025$0$02025-06
Seneca Band Booster ClubEducation501(c)(3)2005$0$02026-06
Seneca Baptist Church501(c)(3)1964
Seneca Blazers of OconeeRecreation and sports501(c)(3)2025
Seneca Middle School Band BoostersArts, culture and humanities501(c)(3)2021$0$02023-06
Seneca Rescue Squad IncPublic safety, disaster preparedness and relief501(c)(3)2022$0$02025-12
Seneca River Baptist Missionary AssociationReligion-related501(c)(3)2018
Seneca Wesleyan Church501(c)(3)1970
Seneca Womans Club Inc501(c)(3)1982$0$02025-12
Sertoma IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2016$0$02024-12
Snow Creek Baptist Church501(c)(3)1964
South Carolina Community FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2023$1,3922025-12
South Carolina Congress of Parents and Teachers501(c)(3)1979$0$02026-06
St Mark United Methodist Church501(c)(3)19742015-12
St Paul the Apostle Church501(c)(3)19462014-06
Steves WayDiseases, disorders and medical disciplines501(c)(3)2026$0$02025-12
Straight Paths Outreach Ministries IncorporatedReligion-related501(c)(3)1996
Student Shop Managers ConsortiumEducation501(c)(3)2020$0$02024-06
The Art Without Boundaries Association IncHealth care501(c)(3)2007$0$02025-12
The CollectiveReligion-related501(c)(3)2021$0$02025-12
The Garage 864 MissionsReligion-related501(c)(3)2024
The Jim Parke FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2002$6.2 million2025-12
Tigers Give BackHuman services501(c)(3)2025
Toys for Tots Golf CharityYouth development501(c)(3)2019$0$02025-12
Tri-County Home EducatorsEducation501(c)(3)2002$0$02025-07
Triangle Fraternity National Council501(c)(7)1940$0$02024-12
Tribble Center FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2025$0$02025-12
Tribble Foundation501(c)(3)1969$1 million2025-06
Tribe UpstateEducation501(c)(3)2026
Trinity Baptist Church501(c)(3)1964
Trout Unlimited501(c)(3)1972$0$02026-03
Truefreedom Ministries of South CarolinaReligion-related501(c)(3)2020
United Assembly of God501(c)(3)1964
United States Power Squadrons501(c)(3)1949$0$02026-02
United States Power Squadrons501(c)(3)1949$0$02025-11
Unlimited Talent Dance FoundationArts, culture and humanities501(c)(3)2026
Utica Baptist Church501(c)(3)1964
Walhalla Junior Womens Club501(c)(3)2015$0$02025-12
Way Youth CenterYouth development501(c)(3)2023$0$02026-01
Wayne & Pauline Thrift Family FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2009$1.4 million2025-12
Welcome Wesleyan Church501(c)(3)19702012-12
White Oak Cliffs AssociationHuman services501(c)(4)2017$0$02025-09
White Stone Freedom FellowshipReligion-related501(c)(3)2011
Windsor 4 Warriors IncHousing and shelter501(c)(3)2024
Wolf Stake Baptist Church501(c)(3)1964
Woodmen of the World Life Insurance Society501(c)(8)1941$0$02025-12
Xo Foundation IncPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2022$0$02024-12

By cause in Seneca, SC

Nonprofits in every city of the state

Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.