Data / Nonprofits / South Carolina / Florence
Nonprofits in Florence, SC: 561 registered with the IRS
561 nonprofits are registered with the IRS in Florence, SC, 474 of them 501(c)(3) charities; the 149 that report revenue took in $3.42 billion. The largest by revenue: McLeod Regional Medical Center of the Pee Dee Inc ($1.49 billion), McLeod Loris Seacoast Hospital ($466.9 million), McLeod Health ($399.6 million). Most common causes: religion-related (76), human services (62), education (48).
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The 500 largest by revenue
| Organization | Category | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|
| McLeod Regional Medical Center of the Pee Dee Inc | Health care | 501(c)(3) | 1975 | $1.49 billion | $3.03 billion | 2025-09 |
| McLeod Loris Seacoast Hospital | Health care | 501(c)(3) | 2013 | $466.9 million | $486.4 million | 2025-09 |
| McLeod Health | Health care | 501(c)(3) | 2003 | $399.6 million | $192.2 million | 2025-09 |
| MPD Electric Cooperative Inc | Public and societal benefit | 501(c)(12) | 2023 | $214.9 million | $401.9 million | 2024-12 |
| McLeod Physician Associates II | Health care | 501(c)(3) | 2006 | $210.1 million | $47.2 million | 2025-09 |
| Hopehealth Inc | Health care | 501(c)(3) | 1995 | $200.5 million | $141.3 million | 2024-12 |
| McLeod Health Clarendon | Health care | 501(c)(3) | 2016 | $102.5 million | $49.7 million | 2025-09 |
| McLeod Medical Center Dillon | Health care | 501(c)(3) | 2003 | $87.6 million | $152.5 million | 2025-09 |
| McLeod Health Cheraw | Health care | 501(c)(3) | 2015 | $84.5 million | $40.8 million | 2025-09 |
| Pee Dee Community Action Agency | 501(c)(3) | 1967 | $18.8 million | $6.9 million | 2024-12 | |
| McLeod Medical Center Foundation | Health care | 501(c)(3) | 1988 | $16.5 million | $36.4 million | 2025-09 |
| United Methodist Manor of the Pee Dee | Human services | 501(c)(3) | 1984 | $14.6 million | $33.5 million | 2025-09 |
| Virtus Academy of South Carolina | Public and societal benefit | 501(c)(3) | 2017 | $10.5 million | $29.7 million | 2025-06 |
| Francis Marion University Development Foundation | Education | 501(c)(3) | 2004 | $7.8 million | $27.1 million | 2025-06 |
| Florence County Commission On Alcohol and Drug Abuse | Mental health and crisis intervention | 501(c)(3) | 1982 | $7.1 million | $7.3 million | 2025-06 |
| Pee Dee Medical & Health Sciences Education Consortium | Education | 501(c)(3) | 2021 | $5.9 million | $27.2 million | 2026-06 |
| Pee Dee Coalition Against Domestic and Sexual Assault | 501(c)(3) | 1986 | $5.8 million | $10.3 million | 2025-06 | |
| Gba Ships Florence Inc | Religion-related | 501(c)(3) | 2007 | $5.7 million | $3.9 million | 2024-12 |
| Nucor Employees Credit Union | 501(c)(14) | 1968 | $4.1 million | $67.3 million | 2025-12 | |
| Francis Marion University Education Foundation | Education | 501(c)(3) | 1975 | $4.1 million | $62 million | 2025-12 |
| Pee Dee Healthy Start Inc | Health care | 501(c)(3) | 1997 | $3.6 million | $585,568 | 2025-09 |
| House of Hope of the Pee Dee | Human services | 501(c)(3) | 1991 | $3.4 million | $5.8 million | 2025-06 |
| City of Florence Public Facilities Corporation | Community improvement and capacity building | 501(c)(3) | 2019 | $3.1 million | $3.8 million | 2025-06 |
| North Eastern Stragetic Alliance Inc | Community improvement and capacity building | 501(c)(3) | 2003 | $3 million | $1.2 million | 2025-06 |
| Eastern Carolina Communityfoundation Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2006 | $2.9 million | $24.1 million | 2024-12 |
| Boys and Girls Clubs of the Pee Dee Area Inc | Youth development | 501(c)(3) | 1965 | $2.8 million | $5.4 million | 2025-12 |
| Building Forence Together CDC | Community improvement and capacity building | 501(c)(3) | 2023 | $2.6 million | $3.3 million | 2025-06 |
| Mercy Medicine Clinic | Health care | 501(c)(3) | 2000 | $2.5 million | $1.6 million | 2025-12 |
| Pee Dee Land Trust | Environment | 501(c)(3) | 1999 | $2 million | $5.8 million | 2025-06 |
| Family Y M C A of Greater Florence | 501(c)(3) | 1972 | $1.8 million | $3.2 million | 2024-12 | |
| Senior Citizens Association in Florence County | Human services | 501(c)(3) | 1969 | $1.6 million | $997,267 | 2025-06 |
| Montessori School of Florence | Education | 501(c)(3) | 1997 | $1.5 million | $2.9 million | 2025-06 |
| Florence Area Humane Society | Animal-related | 501(c)(3) | 1974 | $1.5 million | $3.7 million | 2025-12 |
| Steel Joist Institute | 501(c)(6) | 1942 | $1.4 million | $1.7 million | 2025-12 | |
| Steel Deck Institute | 501(c)(6) | 1957 | $1.3 million | $2.5 million | 2025-12 | |
| Care House of the Pee Dee Inc | Education | 501(c)(3) | 2006 | $1.3 million | $1.4 million | 2025-09 |
| United Way of Florence County | 501(c)(3) | 1956 | $1.1 million | $3.7 million | 2025-06 | |
| School Foundation Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2000 | $954,481 | $2.8 million | 2025-06 |
| The Lighthouse Ministries | Human services | 501(c)(3) | 1998 | $938,593 | $922,631 | 2025-12 |
| Habitat for Humanity International Inc | 501(c)(3) | 1987 | $873,392 | $2.3 million | 2025-06 | |
| Greater Florence Chamber of Commerce | 501(c)(6) | 1945 | $849,093 | $409,086 | 2025-06 | |
| Driving Force Institute for Public Engagement Inc | Arts, culture and humanities | 501(c)(3) | 2021 | $833,800 | $247,720 | 2025-12 |
| Florence-Darlington Technical College Foundation Inc | Education | 501(c)(3) | 1979 | $797,956 | $3 million | 2025-06 |
| Tenacious Grace Ministries | Religion-related | 501(c)(3) | 2016 | $715,887 | $924,061 | 2024-12 |
| Pee Dee Hearing Center | 501(c)(3) | 1972 | $693,650 | $256,846 | 2025-06 | |
| Help 4 Kids Florence | Food, agriculture and nutrition | 501(c)(3) | 2013 | $684,559 | $1.4 million | 2025-12 |
| Pee Dee Regional Emergency Medical | 501(c)(3) | 1980 | $668,968 | $345,530 | 2025-06 | |
| Florence Little Theatre | Arts, culture and humanities | 501(c)(3) | 1968 | $653,301 | $7 million | 2025-06 |
| Precious One Learning Center Inc | 501(c)(3) | 2016 | $593,550 | $968,335 | 2025-12 | |
| New Alpha Community Development Corporation | Community improvement and capacity building | 501(c)(3) | 2016 | $548,334 | $650 | 2025-12 |
| Potter House Recovery | Mental health and crisis intervention | 501(c)(3) | 2022 | $504,643 | $67,143 | 2025-12 |
| Helping Florence Flourish | Community improvement and capacity building | 501(c)(3) | 2019 | $492,131 | $249,881 | 2025-12 |
| Abc Crisis Pregnancy Center Inc | Human services | 501(c)(3) | 2009 | $488,603 | $1.1 million | 2025-12 |
| Florence Soccer Association | Recreation and sports | 501(c)(3) | 1996 | $487,077 | $153,966 | 2024-12 |
| Florence Downtown Development Corporation Inc | Environment | 501(c)(3) | 2003 | $454,920 | $1.2 million | 2025-06 |
| Pelican House Inc | Housing and shelter | 501(c)(3) | 1984 | $454,047 | $986,844 | 2025-09 |
| Realtor Association of the Greater Pee Dee Inc | 501(c)(6) | 1977 | $421,896 | $1.1 million | 2025-12 | |
| Florence Symphony Orchestra | Arts, culture and humanities | 501(c)(3) | 1950 | $390,647 | $481,234 | 2025-06 |
| Applewhite Adoptions | Human services | 501(c)(3) | 2015 | $317,771 | $192 | 2024-12 |
| The Manna House Inc | 501(c)(3) | 1988 | $315,406 | $234,516 | 2025-12 | |
| The Masterworks Choir Inc | 501(c)(3) | 1987 | $298,813 | $209,724 | 2026-06 | |
| Wilson High School Alumni Association Incorporated | Education | 501(c)(3) | 2010 | $241,844 | $212,393 | 2025-12 |
| Trellis Apartments Inc | Human services | 501(c)(3) | 1992 | $199,481 | $531,081 | 2025-06 |
| Pee Dee Housing Development Corporation | 501(c)(3) | 1990 | $194,690 | $1.4 million | 2024-12 | |
| Youth Mentors Association of the | 501(c)(3) | 1954 | $191,814 | $363,337 | 2024-12 | |
| Miracle League of Florence County | Recreation and sports | 501(c)(3) | 2015 | $168,625 | $654,936 | 2026-06 |
| MPD Electric Trust | Human services | 501(c)(3) | 2026 | $168,025 | $373,961 | 2024-12 |
| Palmetto Housing Corporation | Housing and shelter | 501(c)(3) | 1999 | $164,906 | $1.7 million | 2025-09 |
| Rotary International | Community improvement and capacity building | 501(c)(4) | 1966 | $155,216 | $363,144 | 2025-06 |
| Home Builders Association of Greater Pee Dee | 501(c)(6) | 1978 | $154,121 | $127,912 | 2024-12 | |
| Jonathan C Smith Foundation for Bipolar Teens | 501(c)(3) | 2014 | $142,355 | $397,244 | 2025-12 | |
| Windy Hill Volunteer Fire Company Inc | 501(c)(4) | 1975 | $137,469 | $303,413 | 2025-06 | |
| New Hope of Florence Inc | 501(c)(3) | 1994 | $133,514 | $222,407 | 2025-12 | |
| Foster Care Clothing Closet Inc | Human services | 501(c)(3) | 2016 | $127,618 | $385,600 | 2025-12 |
| West Florence All Sports Booster Club | Education | 501(c)(3) | 2014 | $121,413 | $22,678 | 2025-06 |
| South Carolina Association of Tourism | 501(c)(6) | 1996 | $121,000 | $42,154 | 2025-06 | |
| New Hope II of Florence Inc | Human services | 501(c)(3) | 1997 | $120,772 | $361,187 | 2025-12 |
| My Brothers Keeper Shelter | Religion-related | 501(c)(3) | 2019 | $120,265 | $207,140 | 2025-12 |
| Florence County Farm Bureau | 501(c)(5) | 1973 | $117,318 | $874,810 | 2024-12 | |
| Ihope Christian Care and Counseling | Mental health and crisis intervention | 501(c)(3) | 2017 | $116,746 | $19,014 | 2025-12 |
| Florence Tennis Association | Recreation and sports | 501(c)(3) | 2017 | $116,274 | $143,761 | 2023-12 |
| New Beginning Christian Outreach Ministries | Human services | 501(c)(3) | 2020 | $115,920 | $230,730 | 2025-12 |
| Earth & Star Spiritual Wellness Cente | Human services | 501(c)(3) | 2023 | $115,716 | $27,636 | 2025-12 |
| Florence Wine & Food Festival | Recreation and sports | 501(c)(4) | 2019 | $115,341 | $66,402 | 2025-06 |
| Florence County Museum Foundation | Arts, culture and humanities | 501(c)(3) | 2019 | $112,030 | $324,534 | 2025-06 |
| All 4 Autism | Diseases, disorders and medical disciplines | 501(c)(3) | 2014 | $109,609 | $67,790 | 2025-06 |
| Florence Islamic Center Inc | Religion-related | 501(c)(3) | 2011 | $108,460 | $455,631 | 2024-12 |
| Benevolent & Protective Order of Elks of the USA | 501(c)(8) | 1972 | $105,444 | $217,467 | 2025-03 | |
| Florence Area Literacy Council | Education | 501(c)(3) | 1983 | $100,663 | $44,033 | 2024-12 |
| Southeastern Medical International Inc | Health care | 501(c)(3) | 2006 | $91,859 | $45,365 | 2025-12 |
| Transform1 Inc | Religion-related | 501(c)(3) | 2021 | $88,985 | $1 | 2023-12 |
| The Christian Learning Center of Florence County | Human services | 501(c)(3) | 2005 | $83,445 | $213,798 | 2024-12 |
| Jade Bridge | Religion-related | 501(c)(3) | 2017 | $79,866 | $1 | 2025-12 |
| Grand Old Post Office Foundation Inc | Arts, culture and humanities | 501(c)(3) | 2020 | $77,965 | $67,286 | 2025-06 |
| Kingdom Work in Southern Africa Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2009 | $76,328 | $21,346 | 2025-12 |
| Pee Dee Visions Foundation | Recreation and sports | 501(c)(3) | 2000 | $74,262 | $68,746 | 2025-06 |
| The Damon Gun Club | 501(c)(7) | 1981 | $72,600 | $39,019 | 2025-12 | |
| South Carolina Association of School Psychologists | Mutual and membership benefit | 501(c)(6) | 2026 | $68,988 | $69,340 | 2025-06 |
| George Briggs Association of Parents & Teachers | Education | 501(c)(3) | 2000 | $66,629 | $49,332 | 2026-06 |
| Uncle BS Outdoors | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2021 | $64,425 | $2,950 | 2024-12 |
| Florence Area Swim Club | Recreation and sports | 501(c)(3) | 2018 | $60,868 | $5,671 | 2025-12 |
| Archeological Institute of the Pee Dee | Science and technology | 501(c)(3) | 2022 | $58,300 | $49,713 | 2025-06 |
| Friends of Florence County Library Inc | 501(c)(3) | 1980 | $55,984 | $1 million | 2025-12 | |
| Florence Symphony Guild | Arts, culture and humanities | 501(c)(3) | 2007 | $54,623 | $185,802 | 2025-06 |
| Florence Kiwanis Club | Community improvement and capacity building | 501(c)(4) | 2014 | $54,487 | $20,714 | 2025-09 |
| McLaurin Association of Parents and Teachers Inc | Education | 501(c)(3) | 2013 | $54,400 | $94,299 | 2025-06 |
| Parent Booster USA Inc | Education | 501(c)(3) | 2005 | $54,035 | $65,153 | 2026-05 |
| United Steelworkers | 501(c)(5) | 1940 | $53,816 | $164,753 | 2025-12 | |
| American Postal Workers Union | 501(c)(5) | 1973 | $53,501 | $59,010 | 2026-05 | |
| The Naomi Project Inc | Housing and shelter | 501(c)(3) | 2008 | $52,668 | $18,354 | 2025-12 |
| Baroody Pastoral Counseling | Human services | 501(c)(3) | 2002 | $51,469 | $18,735 | 2025-12 |
| Lucy T Davis Elementary Pto | Education | 501(c)(3) | 2014 | $49,372 | $13,518 | 2025-06 |
| International Association of Lions Clubs | 501(c)(4) | $48,058 | $84,212 | 2025-06 | ||
| Ancient Egyptian Arabic Order Nobles Mystic Shrine of N & S Amer | 501(c)(8) | 1972 | $43,721 | $244,601 | 2025-12 | |
| Camp Pee Dee Pride | Youth development | 501(c)(3) | 2002 | $42,874 | $5,028 | 2025-12 |
| Mental Health America of South Carolina | 501(c)(3) | 1976 | $36,100 | $231,541 | 2025-12 | |
| Rotary International | 501(c)(4) | 1958 | $34,947 | $36,580 | 2026-06 | |
| Woodstone Hunting Club Inc | Recreation and sports | 501(c)(7) | 2000 | $34,325 | $31,446 | 2025-12 |
| Winning America Inc | Public and societal benefit | 501(c)(3) | 2017 | $34,085 | $5,672 | 2023-12 |
| Grant Bennett Junior Golf Foundation | Recreation and sports | 501(c)(3) | 2024 | $33,570 | $91,948 | 2025-12 |
| Florence Museum | Arts, culture and humanities | 501(c)(3) | 2022 | $31,194 | $1.1 million | 2025-06 |
| Junior League of Florence SC Inc | Community improvement and capacity building | 501(c)(3) | 1959 | $30,649 | $240,854 | 2025-06 |
| Pee Dee Medical Professionals Association | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2016 | $29,560 | $19,668 | 2025-12 |
| Florence Regional Arts Alliance Inc | 501(c)(3) | 1986 | $29,008 | $31,417 | 2026-06 | |
| Dramatic Coffee Beans Incorporated | Arts, culture and humanities | 501(c)(3) | 2014 | $26,647 | $63,335 | 2024-12 |
| Lifespring Apostolic Center of Excellence | Religion-related | 501(c)(3) | 2016 | $25,769 | $776 | 2025-12 |
| Diversity Works Initiatives | Arts, culture and humanities | 501(c)(3) | 2016 | $25,675 | $5,605 | 2025-12 |
| Florence County Disabilities and Special Needs Board Inc | Human services | 501(c)(3) | 1981 | $25,000 | $326,324 | 2025-06 |
| Communication Workers of America | Community improvement and capacity building | 501(c)(5) | 1951 | $24,518 | $55,320 | 2025-09 |
| Dubs Etc Inc | Education | 501(c)(3) | 2000 | $24,489 | $61,688 | 2025-12 |
| Vithalville Foundation | Human services | 501(c)(3) | 2019 | $21,413 | $721,779 | 2025-12 |
| Stars of Florence | Recreation and sports | 501(c)(3) | 2012 | $21,303 | $660,503 | 2025-12 |
| One Child at A Time | Education | 501(c)(3) | 2019 | $20,091 | $44,904 | 2025-12 |
| Moore Intermediate School Association of Parents and Teacher | Education | 501(c)(3) | 2014 | $18,552 | $6,515 | 2025-06 |
| Pee Dee Equality | 501(c)(3) | 2022 | $17,151 | $20,273 | 2026-06 | |
| Sisters 4 the Future | Housing and shelter | 501(c)(3) | 2016 | $16,033 | $1 | 2025-12 |
| Veterans of Foreign Wars Post 3181 Florence Post | 501(c)(19) | 2026 | $14,546 | $116,378 | 2021-12 | |
| Gods Ministries International Inc | Religion-related | 501(c)(3) | 2005 | $9,336 | $30,461 | 2026-04 |
| Snac | Housing and shelter | 501(c)(3) | 2014 | $8,541 | $8,108 | 2023-12 |
| Wright Foundation for Southern Art | Arts, culture and humanities | 501(c)(3) | 2018 | $7,145 | $120,059 | 2025-06 |
| Ethel S Place Inc | Religion-related | 501(c)(3) | 2024 | $5,338 | $387 | 2024-12 |
| Powerful Advocates | Education | 501(c)(3) | 2022 | $5,250 | $230 | 2025-12 |
| Slains Ministries | Religion-related | 501(c)(3) | 2023 | $5,000 | $517 | 2025-12 |
| Wigc Charitable Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2024 | $3,203 | $43,208 | 2025-12 |
| Ruby Lee Davis Family Communityfoundation Inc | Arts, culture and humanities | 501(c)(3) | 2022 | $2,225 | $4,381 | 2024-12 |
| Carver Elementary School Parent Teachers Organization | Education | 501(c)(3) | 2022 | $1,890 | $14,068 | 2025-07 |
| Cave -Community Action Volunteer Experience | 501(c)(3) | 2021 | $950 | $106 | 2025-12 | |
| Florence County Historical Society Inc | Arts, culture and humanities | 501(c)(3) | 1997 | $112 | $2,679 | 2025-06 |
| Camp Coker Property | Youth development | 501(c)(3) | 2020 | $50 | $195,000 | 2025-12 |
| 100 Black Men of the Greater Pee de E | Youth development | 501(c)(3) | 2026 | |||
| 21St Century Community Economic Development Corporation | Community improvement and capacity building | 501(c)(3) | 2025 | |||
| 412 Initiative | Religion-related | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| 7fourteen | Religion-related | 501(c)(3) | 2025 | $0 | $0 | 2025-10 |
| A Bliss of Harmony Hope | Education | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| A Lady Named Frances | Human services | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| A Mind That Matters | Mental health and crisis intervention | 501(c)(3) | 2025 | |||
| A More Excellent Way | Housing and shelter | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Abundant Faith Worship Center | Religion-related | 501(c)(3) | 2013 | |||
| Agape Academy Inc | Human services | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Aglow International | 501(c)(3) | 1973 | $0 | $0 | 2025-12 | |
| All Saints Episcopal Day School Inc | Education | 501(c)(3) | 2002 | |||
| Amazing Wellness Incorporated | Education | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| American Inns of Court Foundation | 501(c)(3) | 1986 | $0 | $0 | 2025-06 | |
| American Legion | 501(c)(19) | 1946 | $0 | $0 | 2025-12 | |
| American Legion Auxiliary | 501(c)(19) | 1946 | $0 | $0 | 2025-12 | |
| American Legion Auxiliary | 501(c)(19) | 1946 | $0 | $0 | 2023-09 | |
| American Legion Post 1 | 501(c)(19) | 1946 | $0 | $0 | 2025-12 | |
| Ancient Free Masons of South Carolina | 501(c)(10) | 1940 | $0 | $0 | 2025-12 | |
| Ancient Free Masons of South Carolina | 501(c)(10) | 1940 | $0 | $0 | 2025-12 | |
| Angels All Around Ministries Inc | Religion-related | 501(c)(3) | 2014 | |||
| Anointed Touch Ministries | Human services | 501(c)(3) | 2022 | $0 | $0 | 2025-05 |
| Answers Church Ministries | 501(c)(3) | 2014 | ||||
| Antioch Fellowship Church Incorporated | Religion-related | 501(c)(3) | 2006 | |||
| Arborone Flca | 501(c)(1) | 2002 | ||||
| Arie Pickens Educational Center | Religion-related | 501(c)(3) | 2024 | |||
| Assembly of Florence | Recreation and sports | 501(c)(7) | 2010 | $0 | $0 | 2025-12 |
| Astral Link | Public and societal benefit | 501(c)(3) | 2025 | |||
| Aycock Family Foundation Inc | Human services | 501(c)(3) | 2026 | |||
| Back Swamp School Trust Inc | Education | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| Be Transfigured Ministries | Religion-related | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Bea & Ray Norwood Family Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2022 | $1 | 2024-12 | |
| Beacon of Light Institute for Veterans | Human services | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Bethel Family Worship | Religion-related | 501(c)(3) | 2026 | |||
| Black Veterans Village | Mental health and crisis intervention | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Brotherhood of Locomotive Engineers and Trainmen | 501(c)(5) | 1940 | $0 | $0 | 2025-12 | |
| Buffalo Soldiers of South Carolina | Arts, culture and humanities | 501(c)(3) | 2022 | $3,142 | 2025-12 | |
| Burn Care International Inc | Health care | 501(c)(3) | 2010 | $0 | $0 | 2025-12 |
| Business Networking Charities Inc | Community improvement and capacity building | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Calvary Baptist Church | 501(c)(3) | 1964 | 2017-12 | |||
| Caring Hearts of the Pee Dee | Human services | 501(c)(3) | 2015 | $0 | $0 | 2024-12 |
| Carolina Dream Team | Recreation and sports | 501(c)(3) | 2017 | $0 | $1,231 | 2023-12 |
| Carolina Kitties Rescue Inc | Animal-related | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Carolinas Cross Cultural Health Services | Health care | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Carolinas Primary Response Training Center | Public safety, disaster preparedness and relief | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
| Center for Urban Education | Education | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Center of Hope for All People | Religion-related | 501(c)(3) | 2014 | |||
| Central United Methodist Church | 501(c)(3) | 1974 | ||||
| Chain Links | Human services | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Chandler Family Foundation Inc | Housing and shelter | 501(c)(3) | 2025 | |||
| Charlestons Bridge Inc | Crime and legal-related | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Charlie Brown Foundation | Youth development | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Childrens Museum of the Pee Dee | Arts, culture and humanities | 501(c)(3) | 2010 | $0 | $0 | 2024-12 |
| Christ Hand of Mercy Apostolic Church | Religion-related | 501(c)(3) | 1997 | |||
| Christian Assembly | 501(c)(3) | 1964 | ||||
| Church of God By Faith | 501(c)(3) | 1990 | ||||
| Church of God of Prophecy Bible Place | 501(c)(3) | 1969 | ||||
| Class of 1973 Florence Chapter | Education | 501(c)(3) | 2022 | $58 | 2023-12 | |
| Coastal Plain Rural Health Network | Health care | 501(c)(3) | 2008 | $0 | $0 | 2025-12 |
| Coastal Plains Research Center Employees Association | Mutual and membership benefit | 501(c)(4) | 2014 | $0 | $0 | 2023-12 |
| College Park Baptist Church | 501(c)(3) | 1964 | ||||
| Color for Comfort | Arts, culture and humanities | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Connies Workforce Connections | Employment | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Crimestoppers of the Pee Dee Inc | Crime and legal-related | 501(c)(3) | 2020 | $0 | $0 | 2024-12 |
| Crossroads Church of Florence | 501(c)(3) | 1964 | ||||
| Cumberland United Methodist Church | 501(c)(3) | 1974 | ||||
| DRS Bruce & Lee Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2001 | $255.4 million | 2024-12 | |
| Daughters of Isis of North & South America | 501(c)(8) | 1950 | $0 | $0 | 2025-12 | |
| Davis Kids Estates | Human services | 501(c)(3) | 2024 | |||
| Delmae Association of Parents and Teachers | Education | 501(c)(3) | 2022 | $4,100 | 2024-06 | |
| Delta Kappa Gamma Society | 501(c)(6) | 1965 | $0 | $0 | 2026-06 | |
| Delta Sigma Theta Sorority Inc | 501(c)(7) | |||||
| Dhann Youth Empowerment Alliance | Youth development | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Diamond Achievers Incorporated | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2023 | $1 | 2025-12 | |
| Disabled American Veterans | Public and societal benefit | 501(c)(4) | 1942 | $0 | $0 | 2026-06 |
| Disabled American Veterans Auxiliary Inc | 501(c)(4) | 1973 | $0 | $0 | 2025-06 | |
| District Grand Lodge No 13 of South Carolina G U O O F in America | Community improvement and capacity building | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Divine Acts of Kindness | Education | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Dunmore Legacy Foundation | Youth development | 501(c)(3) | 2025 | |||
| E Eden | Human services | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| E Florence | 501(c)(3) | 1964 | ||||
| E L and Theo Windham Charitable Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2002 | $129 | 2025-12 | |
| Ebenezer Baptist Church | 501(c)(3) | 1964 | ||||
| Elaining Hands | Human services | 501(c)(3) | 2024 | |||
| Elijahs Educational Adventurez Cent Er | Human services | 501(c)(3) | 2026 | |||
| Emmanuel Ministries Church | 501(c)(3) | 1983 | ||||
| Empty Arms | Crime and legal-related | 501(c)(3) | 2024 | $0 | $0 | 2025-03 |
| Envoy International | Religion-related | 501(c)(3) | 1991 | $0 | $0 | 2025-12 |
| Eubanks 3 Ministries | Human services | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Faith Kingdom Outreaching Ministries | Religion-related | 501(c)(3) | 2007 | |||
| Faithful Accountable Trustworthy Ho Nest Excellent Role Model Serves G | Community improvement and capacity building | 501(c)(3) | 2025 | |||
| Families Engagement Program Inc | Human services | 501(c)(3) | 2023 | $0 | $0 | 2025-05 |
| Favor Pee Dee Inc | Human services | 501(c)(3) | 2012 | $0 | $0 | 2023-12 |
| Favour Ministries International | 501(c)(3) | 1991 | ||||
| Fearless Phoenix Youth Mentoring | Youth development | 501(c)(3) | 2025 | |||
| Fellowship Assembly | 501(c)(3) | 1974 | ||||
| First Presbyterian Church of Florence | Religion-related | 501(c)(3) | 2013 | 2013-12 | ||
| Flo-Town Elite Phoenix | Recreation and sports | 501(c)(3) | 2024 | |||
| Flo-Town United Classy Queens | Mental health and crisis intervention | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Florence Affordable Housing Corporation | Housing and shelter | 501(c)(3) | 2006 | $0 | $0 | 2023-12 |
| Florence Amatuer Radio Club | Education | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Florence Athletic Hall of Fame Inc | Arts, culture and humanities | 501(c)(3) | 2025 | |||
| Florence Center for Contemporary Music | Arts, culture and humanities | 501(c)(3) | 2023 | $1 | 2024-12 | |
| Florence Chapter Ministries | Religion-related | 501(c)(3) | 2009 | |||
| Florence Chapter of South Carolina State University National Alumni A | 501(c)(3) | 2001 | ||||
| Florence Chinese Christian Church | Religion-related | 501(c)(3) | 2022 | $0 | $0 | 2022-12 |
| Florence Composite Magic City Rollers | Recreation and sports | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Florence County Bar Association Inc | Community improvement and capacity building | 501(c)(6) | 2001 | $0 | $0 | 2025-12 |
| Florence County Master Gardeners Association | Environment | 501(c)(3) | 1999 | $0 | $0 | 2024-04 |
| Florence County Medical Society Inc | Community improvement and capacity building | 501(c)(6) | 1999 | $0 | $0 | 2025-12 |
| Florence First Baptist Church | 501(c)(3) | 1964 | ||||
| Florence Garden Club Council | Environment | 501(c)(3) | 2025 | $0 | $0 | 2026-06 |
| Florence Little League | Recreation and sports | 501(c)(3) | 2025 | |||
| Florence Organized Relief Efforts Inc | 501(c)(3) | 1989 | ||||
| Florence Pickleball Club | Recreation and sports | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Florence Police Fund | Youth development | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Florence Summer Swim League | Recreation and sports | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Florentine Society Inc | Recreation and sports | 501(c)(7) | 2026 | |||
| Floyd Family Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2018 | $11.6 million | 2025-12 | |
| Forget-Me-Not Garden Club | Environment | 501(c)(4) | 2009 | $0 | $0 | 2025-12 |
| Fostered Futures | Human services | 501(c)(3) | 2025 | |||
| Freedom Church | Religion-related | 501(c)(3) | 2022 | |||
| Fresh Start Housing Solutions Non P Rofit | Housing and shelter | 501(c)(3) | 2026 | |||
| Friends of Pee Dee Agriculture and Agribusiness | Education | 501(c)(3) | 2012 | $0 | $0 | 2024-12 |
| Friends of Revolutionary Rivers | Human services | 501(c)(3) | 2020 | $0 | $0 | 2026-06 |
| Full Gospel World Outreach Ministries | Religion-related | 501(c)(3) | 2021 | |||
| Future Entrepreneurs Foundation | Youth development | 501(c)(3) | 2017 | $0 | $0 | 2025-09 |
| Future Paralegals of America A NJ Non Profit Corporation | Crime and legal-related | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| G Lab Legacies Inc | Youth development | 501(c)(3) | 2020 | $0 | $0 | 2024-12 |
| GC2 Ministries | Religion-related | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| GRC - God Restores Comfort Mobile G Rief | Human services | 501(c)(3) | 2026 | |||
| Garden Church of Florence | Religion-related | 501(c)(3) | 2018 | |||
| Gems Connection Ministry | Human services | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Georgetown Community Church Inc | Religion-related | 501(c)(3) | 2000 | 2011-12 | ||
| Girl I Got You | Human services | 501(c)(3) | 2025 | |||
| Global Advocacy and Leadership Network | Civil rights, social action and advocacy | 501(c)(3) | 2025 | |||
| Global Dynamic Prayer Club | Religion-related | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Global Life Changing Women Outreach Ministry | Religion-related | 501(c)(3) | 2026 | |||
| Gods Anointed Academy Inc | Education | 501(c)(3) | 2023 | $0 | $0 | 2024-06 |
| Gold Star Cares Foundation | Health care | 501(c)(3) | 2025 | |||
| Good Shepherd Presbyterian Church Pca | 501(c)(3) | 1974 | ||||
| Gospel Light Bible Church | 501(c)(3) | 1991 | ||||
| Gospel Temple Church Inc | 501(c)(3) | 1964 | ||||
| Grace Baptist Church | 501(c)(3) | 1964 | ||||
| Grace and Truth Christian Church | Religion-related | 501(c)(3) | 2025 | |||
| Greater Vision Tabernacle | 501(c)(3) | 1964 | ||||
| Greater Zion Tabernacle Inc | Religion-related | 501(c)(3) | 2000 | |||
| Greenwood Baptist Church | 501(c)(3) | 1964 | ||||
| Greenwood Elementary School Association of Parents and Teacher | Education | 501(c)(3) | 2013 | $0 | $0 | 2025-07 |
| H M and Pearl Kyle Foundation Inc | 501(c)(3) | 1986 | $2.4 million | 2024-12 | ||
| Harllee Memorial Sculpture Fund | Arts, culture and humanities | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Hatties Helping Hands | Human services | 501(c)(3) | 2024 | |||
| Healthcare Empowerment Access and Logistics | Health care | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Heart of Life | Crime and legal-related | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Heavenly Hugs | Religion-related | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Helps Ministries Incorporated | 501(c)(3) | 1991 | ||||
| Heres Life Florence Inc | Religion-related | 501(c)(3) | 1987 | $0 | $0 | 2026-06 |
| Historic Pentecostal Temple Church of God in Christ | Religion-related | 501(c)(3) | 2022 | $0 | $0 | 2023-12 |
| Hoffmeyer Road Baptist Church | 501(c)(3) | 1964 | ||||
| Holy Temple Pentecostal Assembly | Religion-related | 501(c)(3) | 2003 | |||
| Honest Deceiver Ministries | Religion-related | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Honor Society of Phi Kappa Phi | Education | 501(c)(3) | 1999 | $0 | $0 | 2026-06 |
| House of God Inspirituality Divinity of Divine | Religion-related | 501(c)(3) | 2012 | |||
| Humble Lamb Christian Fellowship | Religion-related | 501(c)(3) | 2003 | |||
| Hypertension and Diabetes Prevention and Treatment Center | Health care | 501(c)(3) | 2019 | $0 | $0 | 2023-12 |
| I Play Florence | Recreation and sports | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| I01k | Youth development | 501(c)(3) | 2026 | |||
| Iglesia Torre Fuerte | 501(c)(3) | 1964 | ||||
| Iheart Foundation | Public and societal benefit | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Immanuel Apostolic Church of Christ | Religion-related | 501(c)(3) | 2022 | |||
| Immanuel Baptist Church | 501(c)(3) | 1964 | ||||
| Immanuel Child Care Ministries | Human services | 501(c)(3) | 1993 | |||
| Improved Benevolent & Protective Order of Elks of the World | 501(c)(8) | 1942 | $0 | $0 | 2025-12 | |
| Incarnate Word Lutheran Church | 501(c)(3) | 1941 | ||||
| Inner Room Ministry Inc | Religion-related | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| International Ambassadors for Christ Ministries Inc | Education | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| International Association of Machinists & Aerospace Workers | 501(c)(5) | 1940 | $0 | $0 | 2025-12 | |
| International Association of Sheet Metal Air Rail & Transportation | Employment | 501(c)(5) | 2015 | $0 | $0 | 2025-12 |
| International Baptist Network Inc | Religion-related | 501(c)(3) | 2005 | |||
| International Pentecostal Holiness Church | 501(c)(3) | 1964 | ||||
| Issv Realty Holdings of South Carolina LLC | 501(c)(3) | 2020 | $0 | $0 | 2021-12 | |
| J&J Leadership Academy | Education | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| JW Moore Middle Band Booster | Arts, culture and humanities | 501(c)(3) | 2022 | $0 | $0 | 2025-08 |
| Jack & Jill of America Inc | 501(c)(4) | 1964 | ||||
| Jamestown Foundation | Religion-related | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Jarrell Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2009 | $435,028 | 2024-12 | |
| Jeffery E Harris Ministries Inc | Religion-related | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Jerry Rivers Ministries Inc | Religion-related | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Junebugs Care | Human services | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Juneteenth Fest | Arts, culture and humanities | 501(c)(3) | 2025 | $0 | $1 | 2025-12 |
| Justin Oconnor Foundation Inc | Human services | 501(c)(3) | 2025 | |||
| Jyes Foundation | Human services | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| K24 Foundation | Education | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Kappa Alpha Psi Fraternity | 501(c)(7) | 1956 | $0 | $0 | 2025-09 | |
| Kappa Delta Sorority | 501(c)(7) | 1970 | $0 | $0 | 2026-06 | |
| Keep Florence Beautiful | Environment | 501(c)(3) | 2011 | $0 | $0 | 2025-12 |
| Kens Corner Foundation | Arts, culture and humanities | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| King of Kings Church of God | 501(c)(3) | 1960 | ||||
| Kingdom Advancement Ministry | Human services | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Kings Academy | 501(c)(3) | 1994 | ||||
| Kingstree Alumni Chapter of Kappa Alpha Psi Fraternity Inc | Education | 501(c)(7) | 2013 | $0 | $0 | 2025-09 |
| Knight Masons of the USA | 501(c)(10) | 1976 | $0 | $0 | 2025-12 | |
| Knights Templar of the United States of America | 501(c)(10) | 1964 | $0 | $0 | 2025-06 | |
| Knights of Columbus | 501(c)(8) | 1940 | $0 | $0 | 2025-12 | |
| Knights of Columbus | 501(c)(8) | 1940 | $0 | $0 | 2025-12 | |
| Knights of the York Cross of Honour Convent General | 501(c)(8) | 1972 | $0 | $0 | 2026-06 | |
| Korean Baptist Church of Florence SC | 501(c)(3) | 1964 | ||||
| League of Women Voters of South Carolina | 501(c)(4) | 1965 | $0 | $0 | 2025-06 | |
| Lester Elementary Association of Pa Rents and Teachers Inc | Education | 501(c)(3) | 2026 | $0 | $0 | 2026-06 |
| Let God Breathe | Religion-related | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Life Cathedral International Ministries | Religion-related | 501(c)(3) | 2019 | |||
| Life Worth Giving Ministries | 501(c)(3) | 1990 | ||||
| Lord Jesus Fund | Community improvement and capacity building | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Love in Action Outreach Ministries Inc | Religion-related | 501(c)(3) | 1999 | $0 | $0 | 2025-12 |
| Lynchburg Cemetery Association Inc | Mutual and membership benefit | 501(c)(13) | 2014 | $0 | $0 | 2025-12 |
| M938 Ministries | Religion-related | 501(c)(3) | 2021 | $0 | $0 | 2026-01 |
| Magiccityquesinc | Community improvement and capacity building | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Marine Conservation Without Borders | Environment | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Marine Corps League | Public and societal benefit | 501(c)(4) | 1946 | $0 | $0 | 2025-06 |
| Mariner Learning Collaborative | Education | 501(c)(3) | 2024 | $0 | $0 | 2025-06 |
| Matthews Farming Community Developm Ent | Food, agriculture and nutrition | 501(c)(3) | 2026 | |||
| McLeod Health Innovation | Health care | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Mental Health Awareness Foundation Inc | 501(c)(3) | 1990 | $6,925 | 2025-12 | ||
| Mentoring for Life | Youth development | 501(c)(3) | 2011 | $0 | $0 | 2024-12 |
| Michelle Law Ministries | Human services | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Mike Coker Ministries | Religion-related | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Minerva Center Foundation | Youth development | 501(c)(3) | 2012 | $0 | $0 | 2025-09 |
| Miracle Deliverance Fellowship Church | Religion-related | 501(c)(3) | 2003 | |||
| Missing Link Street Ministry | Religion-related | 501(c)(3) | 2014 | $0 | $0 | 2023-12 |
| Mission for Christ Inc | 501(c)(3) | 1975 | $0 | $0 | 2025-12 | |
| Mizpah Baptist Church | 501(c)(3) | 1964 | ||||
| Monumental Baptist Church | Religion-related | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Mt Zion United Methodist Church Inc | 501(c)(3) | 1974 | ||||
| Multicultural Community Development Corporation Inc | Community improvement and capacity building | 501(c)(3) | 2002 | $0 | $0 | 2025-12 |
| Music Art Literature & Thought | Youth development | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| National Active and Retired Federal Employees Association | 501(c)(5) | 1963 | $0 | $0 | 2025-12 | |
| National Air Traffic Controllers Association | 501(c)(5) | 1990 | $0 | $0 | 2025-12 | |
| National Alliance for the Mentally Ill of the Pee Dee | 501(c)(3) | 1987 | $0 | $0 | 2025-12 | |
| National Alliance of Postal and Federal Employees | 501(c)(5) | 1945 | $0 | $0 | 2025-12 | |
| National Association of Letter Carriers | 501(c)(5) | 1955 | $0 | $0 | 2025-12 | |
| National Association of Letter Carriers | 501(c)(5) | 1944 | $0 | $0 | 2025-12 | |
| National Council of Negro Women Inc | 501(c)(3) | 1966 | $0 | $0 | 2025-09 | |
| National Council of Negro Women Inc | 501(c)(3) | 1966 | $0 | $0 | 2025-09 | |
| National Council of Negro Women Inc South Carolina Mechanism NCNW | Civil rights, social action and advocacy | 501(c)(3) | 2024 | $0 | $0 | 2025-09 |
| National Kappa Kappa Iota Inc | 501(c)(3) | 1998 | $0 | $0 | 2025-06 | |
| National Society Colonel Dames XVII Century | 501(c)(3) | 1963 | $0 | $0 | 2025-12 | |
| National Society of the Daughters of the American Revolution | 501(c)(3) | 1949 | $0 | $0 | 2025-12 | |
| National Society of the Sons of the American Revolution | Arts, culture and humanities | 501(c)(3) | 1944 | |||
| Neuro Pineal Research Foundation | Medical research | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| New Community Corp | Housing and shelter | 501(c)(3) | 2025 | |||
| New Covenant Baptist Church | 501(c)(3) | 1964 | ||||
| New Grace Temple Church | Religion-related | 501(c)(3) | 2004 | $0 | $0 | 2021-12 |
| New Harvest Presbyterian Church | 501(c)(3) | 1964 | ||||
| New Hope Baptist Church | 501(c)(3) | 1964 | ||||
| New Jerusalem Apostolic Church of Jesus Inc | Religion-related | 501(c)(3) | 2003 | |||
| New Life Assembly of God | 501(c)(3) | 1964 | ||||
| New Life Christian Fellowship Wesleyan Church | 501(c)(3) | 1970 | ||||
| Northgate Baptist Church | 501(c)(3) | 1964 | ||||
| Oakdale Baptist Church | 501(c)(3) | 1964 | ||||
| One Church Florence | Community improvement and capacity building | 501(c)(3) | 2025 | |||
| Open Mic Club | Arts, culture and humanities | 501(c)(3) | 2024 | |||
| Opulence of Hope | Housing and shelter | 501(c)(3) | 2026 | |||
| Order of the Eastern Star of South Carolina | 501(c)(8) | 1972 | $0 | $0 | 2024-12 | |
| Order of the Eastern Star of South Carolina | 501(c)(8) | 1972 | $0 | $0 | 2023-12 | |
| Owen Kenney Family Foundation Inc | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2026 | |||
| PDMH Board Foundation | Mental health and crisis intervention | 501(c)(3) | 2017 | $386,718 | 2024-12 | |
| Paladin Training | Public safety, disaster preparedness and relief | 501(c)(3) | 2011 | $0 | $0 | 2025-12 |
| Palmetto Ballroom Dance Club | Arts, culture and humanities | 501(c)(3) | 2021 | $0 | $0 | 2026-08 |
| Palmetto First Federal Credit Union | 501(c)(1) | 2014-12 | ||||
| Palmetto Housing and Rehabilitation | Recreation and sports | 501(c)(3) | 2010 | $0 | $0 | 2025-07 |
| Palmetto Pearls Foundation | Philanthropy, voluntarism and grantmaking foundations | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Parent Booster USA Inc | Education | 501(c)(3) | 2005 | $0 | $0 | 2025-06 |
| Parent Booster USA Inc | Education | 501(c)(3) | 2005 | $0 | $0 | 2025-05 |
| Parent Booster USA Inc | 501(c)(3) | 2005 | ||||
| Pathway Pentecostal Temple | Religion-related | 501(c)(3) | 2004 | |||
| Pee Dee Botanical Garden | Environment | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Pee Dee Community Fellowship | 501(c)(3) | 1964 | ||||
| Pee Dee Community Outreach | Human services | 501(c)(3) | 2024 | $0 | $0 | 2025-11 |
| Pee Dee Education Foundation | 501(c)(3) | 1987 | $0 | $0 | 2025-12 | |
| Pee Dee Federal Credit Union | 501(c)(1) | 1968 | 2013-12 | |||
| Pee Dee Health Education Partnership | Education | 501(c)(3) | 2011 | $0 | $0 | 2026-06 |
| Pee Dee Homebuilders Scholarship Foundation | 501(c)(3) | 1990 | $52,218 | 2024-12 | ||
| Pee Dee Horsemans Association | Animal-related | 501(c)(3) | 2004 | $0 | $0 | 2025-12 |
| Pee Dee International Aid Pdia | Human services | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Pee Dee Patriots Baseball | Recreation and sports | 501(c)(3) | 2022 | $0 | $0 | 2023-12 |
| Pee Dee Realtor Foundation | Human services | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Pee Dee Regional Development Corporation | Housing and shelter | 501(c)(4) | 1986 | $0 | $67,659 | 2025-09 |
| Pee Dee SHRM Chapter | Community improvement and capacity building | 501(c)(6) | 2026 | $0 | $0 | 2025-12 |
| Pek Foundation Inc | 501(c)(3) | 1987 | $3.1 million | 2025-09 | ||
| Pentecostal United Church of Christ Apostolic | 501(c)(3) | 1985 | ||||
| Peoples United Missionary Baptist Church | Religion-related | 501(c)(3) | 2002 | |||
| Pi Kappa Alpha Fraternity | 501(c)(7) | 1941 | $0 | $0 | 2026-06 | |
| Pi Kappa Alpha Fraternity | 501(c)(7) | 1941 | $0 | $0 | 2026-06 | |
| Pi Kappa Alpha Fraternity | 501(c)(7) | 1941 | $0 | $0 | 2025-06 | |
| Presbyterian Agency for the Developmentally Disabled Inc | 501(c)(3) | 1964 | ||||
| Primezeeacademy | Community improvement and capacity building | 501(c)(3) | 2024 | |||
| Print 4 Good Florence | Youth development | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Progressive Strategies for Family Development | Human services | 501(c)(3) | 2011 | $0 | $0 | 2025-12 |
| Promises Recovery | Mental health and crisis intervention | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Psi Chi the International Honor Society in Psychology | 501(c)(3) | 1957 | $0 | $0 | 2025-06 | |
| Quay Dickens-Jones Memorial Scholarship Foundation Inc | Human services | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Readiness and Resilience Foundation for Those Who Serve | Human services | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Rebirth Community Outreach | Human services | 501(c)(3) | 2024 | $0 | $0 | 2023-12 |
| Redeemed Cathedral Missionary Baptist Church | Religion-related | 501(c)(3) | 2002 | |||
| Rehoboth Baptist Church | 501(c)(3) | 1964 | ||||
| Resurrection Restoration Center for the Homeless | Housing and shelter | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Revivaltime Center of Praise Inc | Religion-related | 501(c)(3) | 2000 | |||
| Rhodes Family International Ministry | Religion-related | 501(c)(3) | 1992 | |||
| Ridgecrest Baptist Church | 501(c)(3) | 1964 | ||||
| Risen Christian Church International | Religion-related | 501(c)(3) | 2012 | |||
| Road Runners Club of America | 501(c)(3) | 1976 | $0 | $0 | 2024-12 | |
| Rolling Thunder Inc | 501(c)(4) | $0 | $0 | 2025-12 | ||
| Rosalyn Cares Foundation | Arts, culture and humanities | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Royal Arch Masons of South Carolina | 501(c)(8) | 1940 | $0 | $0 | 2025-12 | |
| Royal and Select Masters of South Carolina | 501(c)(8) | 1940 | $0 | $0 | 2025-12 | |
| Royall Elementary School Association of Parents and Teacher | Education | 501(c)(3) | 2021 | $0 | $0 | 2026-06 |
| S C Senior Sports Classic Inc | 501(c)(3) | 1993 | $0 | $0 | 2025-09 | |
| SC Medical Group Management Association | Community improvement and capacity building | 501(c)(6) | 2010 | $0 | $0 | 2025-10 |
| SG Group Community Development Corporation | Human services | 501(c)(3) | 2025 | |||
| Saint Catherines Episcopal Church | 501(c)(3) | 1940 | ||||
| Sand Bed Incorporation | Religion-related | 501(c)(3) | 2021 | $0 | $0 | 2023-12 |
| Second Mile Evangelistic Associat Ion | Religion-related | 501(c)(3) | 2003 | $0 | $0 | 2026-06 |
| Seed of Life Worship Ministries Inc | Religion-related | 501(c)(3) | 2015 | |||
| Seminole 6 Sports | Recreation and sports | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Serenity House Assisted Living Facility | Housing and shelter | 501(c)(3) | 2025 | |||
| Shanza Care Closet & Pantry | Food, agriculture and nutrition | 501(c)(3) | 2026 | |||
| Sickle Cell Is Curable | Diseases, disorders and medical disciplines | 501(c)(3) | 2025 | |||
| Sigma Gamma Rho Sorority Inc | 501(c)(7) | 1982 | $0 | $0 | 2026-06 | |
| Sigma Gamma Rho Sorority Inc | 501(c)(7) | 1982 | $0 | $0 | 2026-06 | |
| Sigma Theta Tau International Inc | 501(c)(3) | 1954 | $0 | $0 | 2025-06 | |
| Smart Start Child Development Center | Education | 501(c)(3) | 2025 | |||
| Sneed MS Band Booster Club | Education | 501(c)(3) | 2022 | $0 | $0 | 2025-06 |
| Sneed Middle School Association of Parents Teachers and Students | Education | 501(c)(3) | 2022 | $0 | $0 | 2024-07 |
| Socks 4 the Homeless & Less Fortunate | Human services | 501(c)(3) | 2024 | |||
| Soleful Giving Foundation | Human services | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| South Carolina Alpha Phi Fraternity Leadership Educational & Preventio | Social science | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| South Carolina Dental Connection | Community improvement and capacity building | 501(c)(6) | 2024 | $0 | $0 | 2024-12 |
| South Florence Baptist Church | 501(c)(3) | 1964 | ||||
| Southside Baptist Church | 501(c)(3) | 1964 | ||||
| Speaking Life the Veteran Way | Housing and shelter | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Spiritual Assembly of the Bahais of Florence | 501(c)(3) | 1995 | ||||
| Squeeze Out Foundation | Youth development | 501(c)(3) | 2025 | |||
| St Ann Catholic Church | 501(c)(3) | 1946 | ||||
| St Anthonys Parish | 501(c)(3) | 1946 | ||||
| St Anthonys Parish School | 501(c)(3) | 1946 | ||||
| St John Progressive Church of Jesus | Religion-related | 501(c)(3) | 2003 | |||
| St Johns Church of Florence SC | 501(c)(3) | 1940 | ||||
| St Luke Lutheran Church | 501(c)(3) | 1988 | 2019-12 | |||
| St Paul Florence United Methodist Church | Religion-related | 501(c)(3) | 2025 | |||
| Stirrup Hope Equine Therapy | Animal-related | 501(c)(3) | 2022 | $36,639 | 2025-12 | |
| Sumaco Conservation | Environment | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
By cause in Florence, SC
- Religion-related 76
- Human services 62
- Education 48
- Arts, culture and humanities 28
- Community improvement and capacity building 28
- Recreation and sports 21
- Health care 19
- Youth development 17
- Philanthropy, voluntarism and grantmaking foundations 16
- Housing and shelter 15
- Public and societal benefit 13
- Environment 9
- Mental health and crisis intervention 8
- Crime and legal-related 6
- Animal-related 5
- Food, agriculture and nutrition 3
- Mutual and membership benefit 3
Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.