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Data / Nonprofits / South Carolina / Piedmont

Nonprofits in Piedmont, SC: 117 registered with the IRS

117 nonprofits are registered with the IRS in Piedmont, SC, 104 of them 501(c)(3) charities; the 23 that report revenue took in $157.9 million. The largest by revenue: The Blood Connection Incorporated ($149.7 million), Oasis of Hope Inc ($2.2 million), Roccos Hilltop Ranch Inc ($2.1 million). Most common causes: religion-related (15), human services (12), education (10).

SpecStream is the live web data engine for teams and agents. It reads the IRS register of exempt organizations as the IRS updates it, and this page is that reading. Ask for the nonprofits you need by place, cause and size, with their latest Form 990 figures and websites, and they arrive in your sheet, CRM, Slack or agent.

Every organization, largest by revenue first

OrganizationCategoryTypeSinceRevenueAssetsFiling
The Blood Connection IncorporatedHealth care501(c)(3)1978$149.7 million$107.7 million2025-08
Oasis of Hope IncHuman services501(c)(3)2023$2.2 million$52,3642025-12
Roccos Hilltop Ranch IncAnimal-related501(c)(3)2022$2.1 million$1.9 million2025-12
Power Foundation IncReligion-related501(c)(3)2011$993,359$2.4 million2025-12
Palmetto Innosphere IncScience and technology501(c)(3)2024$384,000$215,9092025-12
Freedom That Lasts MinistriesHuman services501(c)(3)2007$275,370$67,6892025-12
Parent Booster USA IncEducation501(c)(3)2005$252,649$276,8262026-06
South Greenville Lodge No 749 Loyal Order of Moose501(c)(8)1940$231,606$712,4012026-04
Wren Youth AssociationRecreation and sports501(c)(3)2013$201,223$46,2002025-12
Play Powdersville IncRecreation and sports501(c)(3)2022$190,844$79,1222025-06
Powdersville Fire DepartmentPublic safety, disaster preparedness and relief501(c)(3)2003$183,715$749,8042025-12
Band of Brothers Prison Ministry IncHuman services501(c)(3)2003$182,276$80,6612025-12
Battle BuddiesDiseases, disorders and medical disciplines501(c)(3)2014$180,385$16,2232024-12
Piedmont Historical Preservation SocietyArts, culture and humanities501(c)(3)2019$169,766$115,2312025-12
The Wren Band Booster Club Inc501(c)(3)1990$162,318$53,3222026-05
Wren Fire District No 24501(c)(4)1988$140,513$571,9392024-12
Tucker W Hipps Memorial FoundationEducation501(c)(3)2018$91,870$441,8082024-12
Piedmont Emergency Relief CenterHuman services501(c)(3)2022$90,850$82,1982025-12
Parent Booster USA IncEducation501(c)(3)2005$68,156$14,4802026-06
Palmetto Care & Share InstituteHuman services501(c)(3)2022$64,020$58,6172024-12
Wren Elementary Pto IncHuman services501(c)(3)2006$23,314$45,1802025-06
Wild at HeartAnimal-related501(c)(3)2014$8,738$9982025-12
Wren High School Booster Club501(c)(3)1988$1,450$9,7902025-06
2ND Chance 2 RedemptionArts, culture and humanities501(c)(3)2025
4 Gates International MinistriesReligion-related501(c)(3)2020$0$02025-12
Agape Baptist Church501(c)(3)1964
Amp EliteYouth development501(c)(3)2025$0$02025-12
Ancient Free Masons of South Carolina501(c)(10)1940$0$02025-12
Ancient Free Masons of South Carolina501(c)(10)1940$0$02025-12
Angels UnawarePublic and societal benefit501(c)(3)2015$0$02025-09
As the Deer Outdoor MinistriesReligion-related501(c)(3)2006$0$02025-10
Bernies Luv Cancer Outreach IncHuman services501(c)(3)2022$0$02025-12
Bessie Road Baptist Church501(c)(3)1976
Bifrost Health Advocate ServicesHealth care501(c)(3)2018$0$02023-12
Blue CrewCrime and legal-related501(c)(3)2025
Brandons Hoops of HopePublic and societal benefit501(c)(3)2024$0$02025-12
Builders of the AdytumReligion-related501(c)(3)2025$0$02025-12
Calvary Assembly of God501(c)(3)1964
Carolina Immigrant Health InitiativeHealth care501(c)(3)2024$0$02024-12
Carolinas Healthcare Public Relations & Marketing Society501(c)(6)2026
Carpenters House501(c)(3)1964
Church of God of Prophecy Bible Place501(c)(3)1969
Connector 2000 Association IncPublic and societal benefit501(c)(3)19972007-12
Crafted ProducersArts, culture and humanities501(c)(3)2023$0$02025-12
Deborah GenerationReligion-related501(c)(3)2014$0$02025-12
Emerge ChurchReligion-related501(c)(3)2015
Fire Flavor BrigadePublic safety, disaster preparedness and relief501(c)(3)2025
Freedom Fellowship Baptist Church501(c)(3)1964
Freedom Ministries Inc501(c)(3)1982
Fresh Anointed Ministries InternationalReligion-related501(c)(3)2024$0$02025-12
Grace Cathedral Ministries Community Outreach ProgramHuman services501(c)(3)2025$0$02025-12
Grove Station Baptist Church501(c)(3)1964
Healthy Kitchen ProjectFood, agriculture and nutrition501(c)(3)2026
Hope and Essentials Outreach501(c)(3)2026
Human LibertyInternational, foreign affairs and national security501(c)(3)2013$0$02025-12
Iglesia de Cristo Gracia Misericordia Y PazReligion-related501(c)(3)2007
Joy FellowshipReligion-related501(c)(3)2008$0$02025-12
Kaleo Church501(c)(3)1970
La Red Del Pescador501(c)(3)1972
Ladies Auxiliary VFW Department of S CPublic and societal benefit501(c)(19)2010$0$02025-06
Life Church Inc501(c)(3)1964
Living Waters Christian Church Cely LN501(c)(3)1990
Luskin Family FoundationMedical research501(c)(3)2023$0$02024-12
Machen McKenzie Cemetery AssociationMutual and membership benefit501(c)(13)2012$0$02025-12
McGill InstituteEducation501(c)(3)2004$0$02024-12
McLauchlin Ministries IncReligion-related501(c)(3)2026$0$02025-12
Mount Moriah Baptist Church501(c)(3)1964
Mount Valor UniversityEducation501(c)(3)2026
Mountain Springs Baptist Church501(c)(3)1964
Mustard Seed Faith MissionsHuman services501(c)(3)2021$0$02025-12
My OutletEducation501(c)(3)2019$0$02023-12
New Creations Counseling Center IncReligion-related501(c)(3)2021$0$02025-12
On This Rock MinistriesReligion-related501(c)(3)2012$0$02025-12
P LNZ Institute of Musical ArtistryHuman services501(c)(3)2026
Parent Booster USA IncEducation501(c)(3)2005$0$02025-07
Piedmont First Baptist Church501(c)(3)1964
Piedmont Heights Baptist Church501(c)(3)1964
Piedmont Mission Church501(c)(3)1982
Piedmont Village Christmas LightsCommunity improvement and capacity building501(c)(3)2025
Poetic Word Ministries IncReligion-related501(c)(3)2011$0$02025-12
Powdersville P H Church 225501(c)(3)1964
Project Catalyst for YouthYouth development501(c)(3)2026
Pta South Carolina Congress501(c)(3)1979$0$02024-06
Pta South Carolina Congress501(c)(3)1979$0$02026-06
Rehoboth Baptist Church501(c)(3)1964
River Road Baptist Church501(c)(3)1964
Rockvale Baptist Church501(c)(3)1964
Rose Hill Cemetery Association501(c)(13)1994$0$02025-10
Route 1 OutreachHuman services501(c)(3)2014$0$02025-12
SC Ma District 1501(c)(8)1940$0$02025-04
Share Upstate Pregnancy & Infant Lo SS Support IncMental health and crisis intervention501(c)(3)2026
Shelter of United LoveInternational, foreign affairs and national security501(c)(3)2015$0$02025-12
Silver Lining MinistriesAnimal-related501(c)(3)2009$0$02024-12
Solid Ground Ministries IncReligion-related501(c)(3)1998
South Carolina Congress of Parents and TeachersEducation501(c)(3)2024$0$02026-06
South Carolina Congress of Parents and Teachers501(c)(3)1979$0$02025-06
South Carolina Minority Health CenterCommunity improvement and capacity building501(c)(3)2023$0$02024-12
South Greenville Chapter 1552 Women of the Moosee501(c)(8)1940$0$02026-04
South Greenville SportsRecreation and sports501(c)(3)2017$0$02025-12
Spearman Elementary School PtoEducation501(c)(3)2019$0$02025-06
Terry Creek PH Church501(c)(3)1964
The Nurturing GroupCrime and legal-related501(c)(3)2008$0$02025-12
The Upstate Disc Golf ClubRecreation and sports501(c)(3)2025$7,2842025-12
Toastmasters InternationalRecreation and sports501(c)(3)1945$0$02025-12
Total AthleteYouth development501(c)(3)2009$0$02024-12
Trackfun Teaching FoundationPhilanthropy, voluntarism and grantmaking foundations501(c)(3)2025$0$02025-12
Unity Arp Church501(c)(3)1967
Upstate Ruff Ryders South CarolinaYouth development501(c)(3)2024$0$02025-12
VFW Auxiliary VFW Department of S CPublic and societal benefit501(c)(19)2010$0$02024-12
Veterans of Foreign Wars of the United States Dept of So CarolinaPublic and societal benefit501(c)(19)2022$0$02025-12
Victory Baptist Deaf ChurchReligion-related501(c)(3)2025
Vision With A Purpose IncHuman services501(c)(3)2012$0$02025-12
Wings of Deliverance Ministries Incorporated501(c)(3)1992
Woodmen of the World Life Insurance Society501(c)(8)1941$0$02025-12
World Union Evangelism501(c)(3)1991
Wren Baptist Church501(c)(3)1964
Wren Middle School PtsoEducation501(c)(3)2008$0$02025-06

By cause in Piedmont, SC

Nonprofits in every city of the state

Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.