Data / New clinical trials / Puerto Rico

New clinical trials in Puerto Rico: 254 since Nov 2024

Name: New clinical trials in Puerto Rico
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New clinical trials with a site in Puerto Rico: 254 rows for $12.70, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 7 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/country/puerto-rico, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 5, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

254 clinical studies with a site in Puerto Rico were first posted on ClinicalTrials.gov from November 18, 2024 to November 5, 2026; 223 have an industry sponsor and 182 are recruiting or about to. The newest, NCT07919405, was posted on November 5, 2026: A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living... (Novo Nordisk A/S).

The request: Every new clinical trial with a site in Puerto Rico, with the sponsor, phase, conditions and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

254New trials
223Industry sponsored
182Recruiting or not yet
November 5, 2026Latest posted

Newest trials

The newest 100 of 254, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 5, 2026	NCT07919405	A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and...	Novo Nordisk A/S	Phase 3	Not yet recruiting	Hypertension, Obesity	1,408	Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, Denmark, Germany...	clinicaltrials.gov
October 28, 2026	NCT07900633	A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk	Eli Lilly and Company	Phase 3	Not yet recruiting	Obesity, Overweight, Cardiovascular Diseases, Diabetes Mellitus, Type 2	3,000	Argentina, Australia, Brazil, Canada, China, Czechia, France, Germany, Hungary...	clinicaltrials.gov
October 19, 2026	NCT07881458	A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes	Eli Lilly and Company	Phase 3	Recruiting	Obesity, Overweight, Diabetes Mellitus, Type 2	1,000	Brazil, China, Germany, Japan, Puerto Rico, Romania, South Korea, Spain...	clinicaltrials.gov
October 19, 2026	NCT07881432	A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes	Eli Lilly and Company	Phase 3	Not yet recruiting	Obesity	2,115	Argentina, China, Germany, India, Japan, Puerto Rico, South Korea, United...	clinicaltrials.gov
October 13, 2026	NCT07871409	Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight	Amgen	Phase 3	Recruiting	Obesity, Overweight	230	Puerto Rico, United States	clinicaltrials.gov
October 9, 2026	NCT07869043	A Study to Learn About the Study Medicine Called Tilrekimig ( PF-07275315) in People With Severe Asthma	Pfizer	Phase 3	Recruiting	Asthma	1,100	Puerto Rico, United States	clinicaltrials.gov
October 9, 2026	NCT07867080	A Phase 3 Trial for Intravitreal Injection of 4D-150 in Adults With Diabetic Macular Edema (DME).	4D Molecular Therapeutics	Phase 3	Recruiting	Diabetic Macular Edema (DME)	514	China, Japan, Puerto Rico, United States	clinicaltrials.gov
October 6, 2026	NCT07861100	A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular...	Novo Nordisk A/S	Phase 3	Not yet recruiting	Cardiovascular Risk, Obesity	8,500	Argentina, Australia, Brazil, Bulgaria, Canada, China, Czechia, Denmark...	clinicaltrials.gov
September 25, 2026	NCT07840560	Sleep Harmonization Via Bundled Team-Based Interventions in the ICU	University of California, San Diego	Not applicable	Not yet recruiting	Sleep Deprivation, Critical Illness, Sleep-Wake Disorders, Bundle Care, Implementation Science, Delirium	62,500	Puerto Rico, United States	clinicaltrials.gov
September 9, 2026	NCT07808697	A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 in Participants ≥6 Months to <12 Years of Age	ModernaTX, Inc.	Phase 2	Recruiting	SARS-CoV-2	300	Argentina, Dominican Republic, Mexico, Panama, Puerto Rico, United States	clinicaltrials.gov
August 31, 2026	NCT07794579	A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1...	Eli Lilly and Company	Phase 3	Recruiting	Overweight, Prediabetic State, Prehypertension, Obesity, Abdominal	2,001	Argentina, China, Czechia, Germany, India, Japan, Mexico, Puerto Rico, South...	clinicaltrials.gov
August 25, 2026	NCT07783802	A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event	Eli Lilly and Company	Phase 2	Recruiting	Atherosclerosis, Cardiovascular Disease, Obesity, Hypertension, Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic	120	Argentina, Japan, Puerto Rico, United States	clinicaltrials.gov
August 24, 2026	NCT07782970	A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps...	GlaxoSmithKline	Phase 3	Recruiting	Nasal Polyps	218	Japan, Puerto Rico, United States	clinicaltrials.gov
August 21, 2026	NCT07778602	Safety and Feasibility of First-line Avutometinib and Defactinib in Patients With Newly Diagnosed High-grade Gliomas	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Early phase 1	Not yet recruiting	MGMT-unmethylated Glioblastoma (GBM), IDH Wildtype Glioblastoma	22	Puerto Rico, United States	clinicaltrials.gov
August 20, 2026	NCT07775300	A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder	Eli Lilly and Company	Phase 3	Recruiting	Depressive Disorder, Major	1,000	Australia, Brazil, Canada, China, Germany, Greece, Japan, Mexico, Poland...	clinicaltrials.gov
August 20, 2026	NCT07775287	Study of Petosemtamab Plus Chemotherapy Versus Cetuximab or Bevacizumab Plus Chemotherapy in RAS and BRAF Wild Type, Recurrent...	Genmab	Phase 3	Recruiting	Colorectal Cancer	600	Puerto Rico, United States	clinicaltrials.gov
August 14, 2026	NCT07765095	Pericapsular Nerve Group (PENG) Block on Postoperative Pain Management After Acetabular Fracture Fixation	University of Puerto Rico	Not applicable	Recruiting	Acetabular Fractures	56	Puerto Rico	clinicaltrials.gov
August 12, 2026	NCT07759245	A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)	Eli Lilly and Company	Phase 2	Recruiting	Pulmonary Disease, Chronic Obstructive	606	Argentina, Austria, Canada, China, Czechia, Denmark, France, Germany, Hungary...	clinicaltrials.gov
August 10, 2026	NCT07756645	A Study to Assess Intravenous ABBV-1480 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First Line...	AbbVie	Phase 3	Recruiting	Non-Small Cell Lung Cancer	940	Puerto Rico, United States	clinicaltrials.gov
August 7, 2026	NCT07752979	Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities	AbbVie	Phase 2	Recruiting	Obesity, Overweight	360	Puerto Rico, United States	clinicaltrials.gov
August 5, 2026	NCT07748208	A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC)...	Hoffmann-La Roche	Phase 2	Recruiting	Breast Cancer, Diabetes Type II	40	Puerto Rico, United States	clinicaltrials.gov
August 3, 2026	NCT07742644	A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to...	GlaxoSmithKline	Phase 3	Not yet recruiting	Measles, Mumps, Rubella, Varicella (Chickenpox), Measles-Mumps-Rubella+Chickenpox Vaccine	1,860	Argentina, Finland, Italy, Puerto Rico, Taiwan, United States	clinicaltrials.gov
July 23, 2026	NCT07723248	A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With...	ORIC Pharmaceuticals	Phase 3	Recruiting	Metastatic Castration Resistant Prostate Cancer	600	Puerto Rico, United States	clinicaltrials.gov
July 23, 2026	NCT07722546	A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old	Biogen	Phase 2	Recruiting	Graves' Disease	60	Puerto Rico, United States	clinicaltrials.gov
July 17, 2026	NCT07711002	Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy...	AstraZeneca	Phase 3	Recruiting	Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)	1,330	Austria, Brazil, Canada, China, France, Germany, Hong Kong, Hungary, India...	clinicaltrials.gov
July 16, 2026	NCT07708727	Study of an Injectable Regimen of GS-3242 With Lenacapavir Compared to Biktarvy in People New to HIV-1 Treatment	Gilead Sciences	Phase 2/3	Recruiting	HIV-1-infection	700	Canada, Puerto Rico, United States	clinicaltrials.gov
July 14, 2026	NCT07702032	Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic...	Genmab	Phase 3	Recruiting	Left-sided Colorectal Cancer	960	Australia, Puerto Rico, United States	clinicaltrials.gov
July 6, 2026	NCT07684235	Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)	Amgen	Phase 3	Recruiting	Obesity, Overweight	3,200	Australia, Canada, Japan, Puerto Rico, United States	clinicaltrials.gov
July 6, 2026	NCT07684144	Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)	Amgen	Phase 3	Recruiting	Obesity, Overweight, Diabetes Mellitus, Type 2	950	Canada, Japan, Puerto Rico, United Kingdom, United States	clinicaltrials.gov
June 29, 2026	NCT07673887	A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer	Astellas Pharma Global Development, Inc.	Phase 3	Recruiting	Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma	570	China, Japan, Puerto Rico, United States	clinicaltrials.gov
June 29, 2026	NCT07673016	Specimen Collection for Validation of UroAmp: A Next Generation Sequencing Platform for Detection and Surveillance of Bladder Cancer	Convergent Genomics, Inc.	Observational	Recruiting	Bladder Cancer, Urothelial Carcinoma (UC), Hematuria, Upper Tract Urothelial Cancer	2,500	Puerto Rico, United States	clinicaltrials.gov
June 23, 2026	NCT07662109	A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2...	AstraZeneca	Phase 3	Recruiting	Type 2 Diabetes Mellitus	2,000	Argentina, Brazil, China, Czechia, Denmark, Germany, Greece, Hungary, India...	clinicaltrials.gov
June 22, 2026	NCT07661056	Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease	Biohaven Therapeutics Ltd.	Phase 3	Recruiting	Graves Disease	300	Canada, Puerto Rico, United States	clinicaltrials.gov
June 22, 2026	NCT07660198	Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents	Pfizer	Phase 3	Recruiting	Pneumococcal Disease	1,200	Finland, Poland, Puerto Rico, United States	clinicaltrials.gov
June 22, 2026	NCT07659782	A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer	Verastem, Inc.	Phase 2	Recruiting	Non-Small Cell Lung Cancer	105	Australia, Puerto Rico, United States	clinicaltrials.gov
June 18, 2026	NCT07656727	A Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk...	BioAge Labs, Inc.	Phase 2	Active not recruiting	Obesity and Cardiovascular Risk	160	Puerto Rico, United States	clinicaltrials.gov
June 16, 2026	NCT07650916	A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With...	ViiV Healthcare	Phase 3	Recruiting	HIV Infections	564	Argentina, Australia, Brazil, Canada, Japan, Mexico, Puerto Rico, Spain, United...	clinicaltrials.gov
June 12, 2026	NCT07645287	A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1	Gilead Sciences	Phase 2	Recruiting	HIV-1-infection	175	Australia, Canada, Puerto Rico, United States	clinicaltrials.gov
June 12, 2026	NCT07644559	A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer	Verastem, Inc.	Phase 2	Recruiting	Pancreatic Ductal Adenocarcinoma (PDAC), G12D Mutated KRAS	185	Australia, Canada, Puerto Rico, United States	clinicaltrials.gov
June 11, 2026	NCT07641517	A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain	Eli Lilly and Company	Phase 2	Recruiting	Osteoarthritis, Knee, Chronic Pain	150	Puerto Rico, United States	clinicaltrials.gov
June 11, 2026	NCT07641504	A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain	Eli Lilly and Company	Phase 2	Recruiting	Chronic Pain, Low Back Pain	150	Puerto Rico, United States	clinicaltrials.gov
June 10, 2026	NCT07639268	Caregivers-Patients Support to Cope With Advanced-Cancer (CASA)	Ponce Medical School Foundation, Inc.	Not applicable	Enrolling by invitation	Cancer (Advanced Stage), Caregivers, Patients, Stage III Cancer, Stage IV Cancer	124	Puerto Rico	clinicaltrials.gov
June 10, 2026	NCT07639021	A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity	Novo Nordisk A/S	Phase 2	Active not recruiting	Obesity	233	Puerto Rico, United States	clinicaltrials.gov
June 8, 2026	NCT07631637	Study to Evaluate ALN-CIDEB in Adults With Fibrotic Metabolic Dysfunction-Associated Steatohepatitis (MASH)	Regeneron Pharmaceuticals	Phase 2	Recruiting	Metabolic Dysfunction-Associated Steatohepatitis, MASH	360	Puerto Rico, United Kingdom, United States	clinicaltrials.gov
June 5, 2026	NCT07629440	A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.	Pfizer	Phase 3	Recruiting	Pneumococcal Disease	3,230	Japan, Puerto Rico, United States	clinicaltrials.gov
May 28, 2026	NCT07610837	Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis	AstraZeneca	Phase 2	Recruiting	Liver Fibrosis, Hepatic Cirrhosis	104	Puerto Rico, United States	clinicaltrials.gov
May 27, 2026	NCT07609719	A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy	Genentech, Inc.	Phase 4	Recruiting	Multiple Sclerosis	100	Puerto Rico, United States	clinicaltrials.gov
May 22, 2026	NCT07602582	A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).	Eli Lilly and Company	Phase 3	Recruiting	Alzheimer Disease, Dementia, Plaque, Amyloid	550	Japan, Puerto Rico, United States	clinicaltrials.gov
May 18, 2026	NCT07592273	Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved...	AbbVie	Phase 2/3	Recruiting	Diabetic Retinopathy	576	Puerto Rico, United States	clinicaltrials.gov
May 8, 2026	NCT07575399	Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in...	Amgen	Phase 3	Recruiting	Obesity or Overweight	300	Puerto Rico, United States	clinicaltrials.gov
May 7, 2026	NCT07573215	Expanded Access Program for Daraxonrasib (RMC-6236) in Previously Treated Metastatic Pancreatic Adenocarcinoma	Revolution Medicines, Inc.	Not applicable	Approved for marketing	PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, Metastatic Pancreas Adenocarcinoma, Pancreatic Cancer, Pancreatic Cancer...	Not listed	Puerto Rico, United States	clinicaltrials.gov
May 6, 2026	NCT07571252	Impact of Preemptive Analgesia on Postoperative Pain in Orthognathic Surgery	University of Puerto Rico	Phase 4	Recruiting	Post Operative Pain, Orthognathic Surgery	72	Puerto Rico	clinicaltrials.gov
May 5, 2026	NCT07567001	A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity	Novo Nordisk A/S	Phase 3	Recruiting	Obesity, Heart Failure	5,610	Argentina, Australia, Brazil, Bulgaria, Canada, China, Czechia, Denmark...	clinicaltrials.gov
April 29, 2026	NCT07555938	Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple...	Hoffmann-La Roche	Phase 3	Recruiting	Multiple Myeloma	380	Australia, Brazil, Canada, China, Czechia, Denmark, France, Germany, Greece...	clinicaltrials.gov
April 28, 2026	NCT07553429	A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated	Boehringer Ingelheim	Phase 1/2	Recruiting	Diabetic Macular Edema	49	Puerto Rico, United States	clinicaltrials.gov
April 22, 2026	NCT07546500	A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian...	K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc	Phase 3	Recruiting	Ovarian Cancer	420	Argentina, Australia, Belgium, Brazil, Canada, Croatia, Denmark, Estonia...	clinicaltrials.gov
April 13, 2026	NCT07522073	A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal...	Incyte Corporation	Phase 3	Recruiting	Solid Tumors	588	Australia, Austria, Belgium, Canada, Denmark, Finland, France, Georgia...	clinicaltrials.gov
April 9, 2026	NCT07519655	Phase 1 Study of PF-08046033 in Advanced Solid Tumors	Pfizer	Phase 1	Recruiting	Non-Small-Cell Lung, Esophageal Cancer, Cutaneous Melanoma	250	France, Netherlands, Puerto Rico, South Korea, Spain, United States	clinicaltrials.gov
April 8, 2026	NCT07517263	An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen...	Novartis Pharmaceuticals	Phase 3	Active not recruiting	Cardiovascular Disease and Lipoprotein(a)	5,700	Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China...	clinicaltrials.gov
April 3, 2026	NCT07509307	AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis...	Novo Nordisk A/S	Phase 3	Recruiting	Obesity, Overweight, Osteoarthritis, Knee	400	Australia, Bulgaria, Canada, Denmark, Greece, Italy, Poland, Puerto Rico...	clinicaltrials.gov
March 25, 2026	NCT07492641	BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not...	BeOne Medicines	Phase 3	Recruiting	HR+/HER2- Breast Cancer	1,056	Australia, Brazil, China, France, Germany, Italy, Japan, Malaysia, Poland...	clinicaltrials.gov
March 23, 2026	NCT07489066	Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC	Pfizer	Phase 2	Recruiting	Carcinoma, Non-Small-Cell Lung, Lung Cancer (NSCLC), Lung Neoplasms, Carcinoma, Non-Small-Cell Lung (NSCLC), Lung...	120	Australia, China, Germany, Hong Kong, Israel, Italy, Poland, Puerto Rico...	clinicaltrials.gov
March 19, 2026	NCT07484074	A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324	Ollin Biosciences, Inc.	Phase 1	Completed	Diabetic Macular Edema (DME), Neovascular (Wet) Age-Related Macular Degeneration	164	Puerto Rico, United States	clinicaltrials.gov
March 4, 2026	NCT07448714	Animal Assisted Therapy	University of Puerto Rico	Not applicable	Completed	Dental Fear and Anxiety, Animal Assisted Therapy, Dental Treatment	20	Puerto Rico	clinicaltrials.gov
March 2, 2026	NCT07441642	A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related...	Novartis Pharmaceuticals	Phase 2	Recruiting	Geographic Atrophy Secondary to Age-related Macular Degeneration	272	Argentina, Australia, Brazil, Bulgaria, Canada, China, Colombia, Czechia...	clinicaltrials.gov
February 27, 2026	NCT07440225	A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)	EyeBiotech Ltd.	Phase 2/3	Recruiting	Macular Degeneration, Age-Related Macular Degeneration, Choroidal Neovascularization, Wet Macular Degeneration	960	Argentina, Australia, Estonia, Germany, Israel, Latvia, Poland, Puerto Rico...	clinicaltrials.gov
February 27, 2026	NCT07437950	Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment...	National Cancer Institute (NCI)	Phase 2	Recruiting	Acute Myeloid Leukemia	126	Puerto Rico, United States	clinicaltrials.gov
February 24, 2026	NCT07431281	Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric...	AstraZeneca	Phase 3	Recruiting	Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Esophageal Cancer	2,130	Australia, Austria, Belgium, Brazil, Canada, China, France, Germany, Hungary...	clinicaltrials.gov
February 20, 2026	NCT07424404	A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in...	Karuna Therapeutics, Inc., a Bristol Myers Squibb company	Phase 3	Recruiting	Schizophrenia, Autism-Related Irritability	400	Australia, Canada, France, Hungary, India, Japan, Poland, Puerto Rico, Romania...	clinicaltrials.gov
February 19, 2026	NCT07421700	Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer	Pfizer	Phase 1/2	Recruiting	Urothelial Cancer, Advanced/Metastatic Urothelial Cancer, Urothelial Carcinoma	132	Australia, China, Japan, Puerto Rico, Spain, United States	clinicaltrials.gov
February 19, 2026	NCT07420283	A Study of Brenipatide in Participants With Opioid Use Disorder	Eli Lilly and Company	Phase 2	Recruiting	Opioid Use Disorder	465	Canada, Puerto Rico, United Kingdom, United States	clinicaltrials.gov
February 17, 2026	NCT07415044	LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis	Eli Lilly and Company	Phase 2	Recruiting	Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe	1,431	Argentina, Brazil, Canada, China, Colombia, Croatia, Czechia, France, Greece...	clinicaltrials.gov
February 17, 2026	NCT07412756	A Study of Brenipatide in Adult Participants With Major Depressive Disorder	Eli Lilly and Company	Phase 3	Recruiting	Depressive Disorder, Major	1,000	Australia, Brazil, Canada, China, Germany, Greece, Japan, Mexico, Poland...	clinicaltrials.gov
February 6, 2026	NCT07392892	Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer	Pfizer	Phase 2/3	Recruiting	Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma, Metastatic Gastric...	840	Canada, China, France, Israel, Italy, Japan, Puerto Rico, Spain, Taiwan, United...	clinicaltrials.gov
February 6, 2026	NCT07392190	A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin	Eli Lilly and Company	Phase 3	Recruiting	Overweight, Obesity	900	Australia, Belgium, Brazil, China, Czechia, India, Israel, Japan, Mexico...	clinicaltrials.gov
February 6, 2026	NCT07391774	Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the...	National Cancer Institute (NCI)	Phase 3	Recruiting	Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer...	1,978	Puerto Rico, United States	clinicaltrials.gov
February 5, 2026	NCT07388498	A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via...	Amgen	Phase 3	Recruiting	Uncontrolled Gout	270	Puerto Rico, United States	clinicaltrials.gov
January 27, 2026	NCT07369102	Esketamine With or Without Integration Therapy for Treatment-Resistant Depression	University of Puerto Rico	Phase 4	Recruiting	Treatment-resistant Depression (TRD)	20	Puerto Rico	clinicaltrials.gov
January 21, 2026	NCT07353931	Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight	Eli Lilly and Company	Phase 3	Recruiting	Osteoarthritis, Overweight or Obesity	900	Argentina, Belgium, Canada, China, Czechia, Denmark, Germany, Japan, Puerto...	clinicaltrials.gov
January 20, 2026	NCT07351058	A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes	Hoffmann-La Roche	Phase 3	Recruiting	Obesity or Overweight, Type 2 Diabetes Mellitus	1,600	Argentina, Australia, Brazil, Canada, China, Czechia, France, Germany, India...	clinicaltrials.gov
January 16, 2026	NCT07348692	Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age	Sanofi	Phase 3	Recruiting	Pneumococcal Immunization, Healthy Volunteers	2,195	Honduras, Puerto Rico, Thailand, United States	clinicaltrials.gov
January 7, 2026	NCT07321886	A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes	Eli Lilly and Company	Phase 3	Recruiting	Obesity, Overweight	1,980	Argentina, Australia, Belgium, Brazil, Canada, China, Germany, India, Japan...	clinicaltrials.gov
December 29, 2025	NCT07308158	Covid Flu A/B and RSV 4 in 1 Diagnostic Test	iHealth Labs inc	Observational	Completed	Influenza A, Influenza B, COVID - 19, RSV	1,119	Puerto Rico, United States	clinicaltrials.gov
December 23, 2025	NCT07299019	A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis	Zenas BioPharma (USA), LLC	Phase 3	Recruiting	Secondary Progressive Multiple Sclerosis	990	Australia, Belgium, Bulgaria, Croatia, Czechia, Estonia, France, Georgia...	clinicaltrials.gov
December 16, 2025	NCT07286175	A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)	Eli Lilly and Company	Phase 2	Recruiting	Bipolar Disorder	400	Argentina, Brazil, China, India, Japan, Mexico, Puerto Rico, United States	clinicaltrials.gov
December 16, 2025	NCT07286058	Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis	Takeda	Phase 3	Recruiting	Psoriatic Arthritis	1,182	Australia, China, Croatia, Czechia, Estonia, Germany, Hungary, Israel, Japan...	clinicaltrials.gov
December 16, 2025	NCT07285798	A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder	Bristol-Myers Squibb	Phase 3	Not yet recruiting	Irritability Associated With Autism Spectrum Disorder	176	France, Germany, Hungary, India, Japan, Poland, Puerto Rico, Romania, Spain...	clinicaltrials.gov
December 16, 2025	NCT07285018	A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain	Eli Lilly and Company	Phase 2	Recruiting	Diabetic Peripheral Neuropathic Pain	150	Puerto Rico, United States	clinicaltrials.gov
December 16, 2025	NCT07284901	Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes	Kailera	Phase 3	Active not recruiting	Obesity With Diabetes, Overweight With Diabetes	1,270	Argentina, Australia, Bulgaria, Czechia, Germany, New Zealand, Poland, Puerto...	clinicaltrials.gov
December 16, 2025	NCT07284849	A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line...	Incyte Corporation	Phase 3	Recruiting	CRC (Colorectal Cancer)	700	Argentina, Australia, Austria, Belgium, Brazil, Canada, China, Denmark, France...	clinicaltrials.gov
December 16, 2025	NCT07284745	A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism	Bristol-Myers Squibb	Phase 3	Not yet recruiting	Irritability Associated With Autism Spectrum Disorder	176	Australia, Canada, Puerto Rico, United States	clinicaltrials.gov
December 16, 2025	NCT07283939	Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays	Alliance for Clinical Trials in Oncology	Not applicable	Recruiting	Ampulla of Vater Carcinoma, Appendix Carcinoma, Carcinoma of Unknown Primary With Gastrointestinal Profile, Colon...	420	Guam, Puerto Rico, United States	clinicaltrials.gov
December 15, 2025	NCT07282600	A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes	Eli Lilly and Company	Phase 3	Recruiting	Overweight, Obesity	1,035	China, Czechia, Germany, India, Japan, Mexico, Poland, Puerto Rico, Slovakia...	clinicaltrials.gov
December 11, 2025	NCT07276581	A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis	AstraZeneca	Phase 2	Recruiting	Rheumatoid Arthritis	320	Argentina, Brazil, Bulgaria, Canada, Chile, China, Germany, Hungary, Japan...	clinicaltrials.gov
November 26, 2025	NCT07252232	Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)	Revolution Medicines, Inc.	Phase 3	Recruiting	Pancreatic Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma (PDAC)...	500	Canada, France, Germany, Italy, Japan, Puerto Rico, South Korea, Spain, United...	clinicaltrials.gov
November 20, 2025	NCT07238088	Active Mammography and Counseling	University of Puerto Rico Comprehensive Cancer Center	Not applicable	Recruiting	Breast Cancer Prevention	1,020	Puerto Rico	clinicaltrials.gov
November 17, 2025	NCT07230834	Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants	Regeneron Pharmaceuticals	Phase 1	Recruiting	Geographic Atrophy (GA)	54	Georgia, Puerto Rico, Romania, United States	clinicaltrials.gov
November 14, 2025	NCT07228832	Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer	Summit Therapeutics	Phase 3	Recruiting	Metastatic Colorectal Cancer (CRC)	900	Belgium, Canada, China, Czechia, France, Germany, Hungary, Italy, Japan...	clinicaltrials.gov
November 13, 2025	NCT07227818	Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia	Neurocrine Biosciences	Phase 3	Recruiting	Schizophrenia	560	Puerto Rico, Serbia, United States	clinicaltrials.gov
November 12, 2025	NCT07227298	Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced...	Pfizer	Phase 1/2	Recruiting	Advanced/Metastatic Non-Small Cell Lung Cancer, Carcinoma, Non-Small Cell Lung, Non-Small Cell Lung Cancer	162	China, France, Germany, Italy, Japan, Puerto Rico, Spain, Taiwan, United States	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Eli Lilly and Company	35	October 28, 2026
Pfizer	24	October 9, 2026
AbbVie	13	August 10, 2026
Amgen	9	October 13, 2026
AstraZeneca	9	July 17, 2026
Bristol-Myers Squibb	9	December 16, 2025
Hoffmann-La Roche	8	August 5, 2026
University of Puerto Rico	7	August 14, 2026
Novo Nordisk A/S	6	November 5, 2026
Boehringer Ingelheim	6	April 28, 2026
Novartis Pharmaceuticals	6	April 8, 2026
Ponce Medical School Foundation, Inc.	5	June 10, 2026
Sanofi	5	January 16, 2026
GlaxoSmithKline	4	August 24, 2026
Genmab	4	August 20, 2026
Incyte Corporation	4	April 13, 2026
BeOne Medicines	4	March 25, 2026
National Cancer Institute (NCI)	4	February 27, 2026
Merck Sharp & Dohme LLC	4	June 10, 2025
Genentech, Inc.	3	May 27, 2026

Conditions

Condition group	New trials	Latest
Obesity	35	November 5, 2026
Overweight	28	October 28, 2026
Diabetes Mellitus, Type 2	14	October 28, 2026
Carcinoma, Non-Small-Cell Lung	12	August 10, 2026
Colorectal Neoplasms	10	August 20, 2026
Breast Neoplasms	7	August 5, 2026
Hypertension	6	November 5, 2026
Cardiovascular Diseases	6	October 28, 2026
Atherosclerosis	6	August 25, 2026
Pancreatic Neoplasms	6	June 12, 2026
Alzheimer Disease	6	May 22, 2026
Neoplasm Metastasis	6	October 30, 2025
COVID-19	5	September 9, 2026
Depression	5	August 20, 2026
Lung Neoplasms	5	April 9, 2026
Colonic Neoplasms	5	December 16, 2025
Lung Diseases	4	August 12, 2026
Prostatic Neoplasms	4	July 23, 2026
Recurrence	4	July 23, 2026
Pneumococcal Infections	4	June 22, 2026
Ovarian Neoplasms	4	April 22, 2026
Esophageal Neoplasms	4	April 9, 2026
Colitis, Ulcerative	4	February 17, 2026
Uterine Cervical Neoplasms	4	August 7, 2025
Coronavirus Infections	3	September 9, 2026

By phase

Phase	New trials	Latest
Phase 3	141	November 5, 2026
Phase 2	48	September 9, 2026
Not applicable	22	September 25, 2026
Phase 1	10	April 9, 2026
Phase 1/2	9	April 28, 2026
Phase 2/3	8	July 16, 2026
Observational	8	June 29, 2026
Phase 4	7	May 27, 2026
Early phase 1	1	August 21, 2026

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.