Data / New clinical trials / Opioid-Related Disorders

Opioid-Related Disorders trials: 183 new since Nov 2024

Name: New Opioid-Related Disorders clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Opioid-Related Disorders clinical trials: 183 rows for $9.15, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 7 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/opioid-related-disorders, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated October 28, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

183 clinical studies in Opioid-Related Disorders were first posted on ClinicalTrials.gov from November 12, 2024 to October 28, 2026; 12 have an industry sponsor and 131 are recruiting or about to. The newest, NCT07900828, was posted on October 28, 2026: Peer-led, Mobile App Supported Linkage to Opioid Use Disorder Treatment (Johns Hopkins University).

The request: Every new Opioid-Related Disorders clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

183New trials
12Industry sponsored
131Recruiting or not yet
October 28, 2026Latest posted

Newest trials

The newest 100 of 183, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
October 28, 2026	NCT07900828	Peer-led, Mobile App Supported Linkage to Opioid Use Disorder Treatment	Johns Hopkins University	Not applicable	Not yet recruiting	Opioid Use Disorder	90	United States	clinicaltrials.gov
October 26, 2026	NCT07894276	Pain Sensitivity, Alcohol-Induced Analgesia, and Heavy Drinking in Individuals With Opioid Use Disorder	Ohio State University	Early phase 1	Not yet recruiting	Opioid Use Disorder, Alcohol Intoxication, Pain	90	United States	clinicaltrials.gov
October 21, 2026	NCT07886944	PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial)	Chestnut Health Systems	Not applicable	Enrolling by invitation	Burnout, Secondary Trauma, Compassion Fatigue, Opioid Use Disorder, Stimulant Use Disorder, Substance Use Disorder	200	United States	clinicaltrials.gov
October 21, 2026	NCT07886606	Cannabidiol in Opioid Use Disorder and Chronic Pain With Buprenorphine	Yale University	Early phase 1	Recruiting	Chronic Pain, Opioid Use Disorder	34	United States	clinicaltrials.gov
October 15, 2026	NCT07875361	Disease Intervention Specialist (DIS) for SUD	Ohio State University	Observational	Not yet recruiting	Substance Use Disorder (SUD), Opioid Use Disorder, Alcohol Use Disorder (AUD), Drug Use, Overdose	1,200	United States	clinicaltrials.gov
October 15, 2026	NCT07874620	A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain	Adneuris Therapeutics, Inc.	Phase 2	Recruiting	Chronic Pain, Pain, Opioid Withdrawal (Disorder), Opioid Use Disorder	45	United States	clinicaltrials.gov
October 14, 2026	NCT07873944	Recovery Management Checkup Scalability and Sustainability Hybrid Experiment	Chestnut Health Systems	Phase 3	Not yet recruiting	Substance Use Disorder (SUD), Opioid Use Disorders, Stimulant Overdose, Overdose Risk, Alcohol Use Disorder	600	United States	clinicaltrials.gov
October 13, 2026	NCT07871877	Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder	Clive Michelsen	Phase 1/2	Not yet recruiting	Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders	60	United States	clinicaltrials.gov
October 8, 2026	NCT07865078	Adapting and Implementing a Chronic Disease Self-Management Program for Primary Care Patients With Opioid Use Disorder and Serious Mental...	University of Utah	Not applicable	Not yet recruiting	Implementation Science, Chronic Disease Self-management, Mental Illness, Addiction, Primary Care Patients With Chronic...	40		clinicaltrials.gov
September 29, 2026	NCT07846735	Youth Overdose & Use Reduction in Rural Systems	Seattle Children's Hospital	Not applicable	Not yet recruiting	Substance Abuse, Opioid Abuse (Disorder), Overdose Prevention, Substance Use Disorder (SUD), Adolescent Substance Use...	550		clinicaltrials.gov
September 25, 2026	NCT07842601	Helping Kentuckians Overcome Depression and Opioid Addiction With Brain Stimulation	University of Kentucky	Not applicable	Not yet recruiting	Opioid Use Disorder, Major Depressive Disorder (MDD)	60	United States	clinicaltrials.gov
September 24, 2026	NCT07839182	Measurement-Based Care to Support Buprenorphine-Naloxone Treatment in Outpatient Addiction Clinics	Vanderbilt University Medical Center	Not applicable	Not yet recruiting	Opioid Use Disorder	140	United States	clinicaltrials.gov
September 9, 2026	NCT07810322	Pilot Testing of the emPath Platform to Improve Medication for Opioid Use Disorder (MOUD) Linkage and Retention Among Adults With Opioid...	Duke University	Not applicable	Recruiting	Opioid Use Disorder, Digital Health Intervention, Telemedicine, Outreach Intervention	80	United States	clinicaltrials.gov
September 2, 2026	NCT07800520	Characterization of CB1 Receptors Using [11-C]OMAR in Opioid Use Disorder	Yale University	Phase 1	Recruiting	Opioid Use Disorder, OAT	110	United States	clinicaltrials.gov
August 31, 2026	NCT07795840	The ConCERN Intervention for Loved Ones of Those With Opioid Use Disorder	University of Michigan	Not applicable	Not yet recruiting	Opioid Use Disorder	700	United States	clinicaltrials.gov
August 28, 2026	NCT07793383	Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 3	Yale University	Not applicable	Recruiting	Opioid Abuse (Disorder), Clinical Decision Support	100	United States	clinicaltrials.gov
August 26, 2026	NCT07787039	Supporting Treatment for Opioids and Recovery Capital (STORC) - R61 Phase	Friends Research Institute, Inc.	Not applicable	Recruiting	Opioid Use Disorder	10	United States	clinicaltrials.gov
August 21, 2026	NCT07780097	TRTME: Improving Outpatient Initiation of Medication for Opioid Use Disorder Following Hospitalization	T. John Winhusen, PhD	Not applicable	Enrolling by invitation	Opioid Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe	30	United States	clinicaltrials.gov
August 21, 2026	NCT07778511	How Does the Opioid System Shape Stress and Social Behaviour in Men and Women and What Role Does Childhood Unpredictability Play?	Sara L. Kroll	Not applicable	Recruiting	Stress, Early Life Stress, Sex Differences, Opioid	72	Switzerland	clinicaltrials.gov
August 21, 2026	NCT07778394	Personalized Addiction Treatment enHancement	Rhode Island Hospital	Not applicable	Recruiting	Opioid Use Disorder, mHealth, Peer Support	40	United States	clinicaltrials.gov
August 18, 2026	NCT07770555	Deep Transcranial Magnetic Stimulation for Tobacco Cessation in Adults With Opioid Use Disorder	Payel Roy	Not applicable	Not yet recruiting	Opioid Use Disorder, Tobacco Use Disorder	12	United States	clinicaltrials.gov
August 6, 2026	NCT07750639	Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity	AdventHealth	Phase 4	Enrolling by invitation	Opioid Abuse (Disorder), Opioid Analgesia, Opioid Analgesic Adverse Reaction, Opioid Consumption	300	United States	clinicaltrials.gov
July 30, 2026	NCT07737652	Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders	University of Alabama, Tuscaloosa	Not applicable	Completed	Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder	61	United States	clinicaltrials.gov
July 29, 2026	NCT07734623	Applying Low-Intensity Focused Ultrasound in Treating Severe Substance Use Disorder: Tolerability and Effectiveness	National Taiwan University Hospital	Not applicable	Recruiting	Opioid Use Disorder, Severe, Amphetamine Use Disorder	60	Taiwan	clinicaltrials.gov
July 24, 2026	NCT07725289	Clinician Practice Companion to Address Youth Substance Use	Massachusetts General Hospital	Not applicable	Not yet recruiting	Substance Use, Substance-Related Disorders, Adolescent Substance Use, Cannabis Use, Opioid Use Disorder, Drug Overdose...	60	Canada, United States	clinicaltrials.gov
July 17, 2026	NCT07711795	Mindfulness Texting for Medication Adherence and Chronic Pain Management	University of New Mexico	Not applicable	Recruiting	Opioid Use Disorder (OUD), Chronic Pain	60	United States	clinicaltrials.gov
July 16, 2026	NCT07707934	Methadone Expansion in Detention Though the Hospital/Clinic Designation	Brendan Saloner	Not applicable	Not yet recruiting	Opioid Use Disorder, Incarcerated Individuals, Methadone Maintenance	30		clinicaltrials.gov
July 9, 2026	NCT07693270	Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery	University of California, San Diego	Observational	Recruiting	Opioid Use Disorder, Opioid Consumption, Persistent Opioid Use, Persistent Postsurgical Pain	100	United States	clinicaltrials.gov
June 25, 2026	NCT07668635	Cannabis Effects on Opioid Self-Administration	Shanna Babalonis, PhD	Phase 1	Not yet recruiting	Opioid Use Disorder, Cannabis Use	30	United States	clinicaltrials.gov
June 24, 2026	NCT07665502	Pre-Pilot (R61) WINGS+++: mHealth to Improve MOUD Uptake in Women Experiencing Intimate Partner Violence and PTSD	Dawn A. Goddard-Eckrich	Not applicable	Enrolling by invitation	Opioid-Related Disorders, Substance-Related Disorders, Intimate Partner Violence (IPV), Stress Disorders...	7	United States	clinicaltrials.gov
June 22, 2026	NCT07661823	QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos....	Veterans Recovery Network Inc.	Not applicable	Not yet recruiting	Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism, ADHD - Attention Deficit Disorder With Hyperactivity...	1,000,000	United States	clinicaltrials.gov
June 22, 2026	NCT07661446	Cannabis and Opioid Use Disorder, Study 2	University of Kentucky	Phase 1	Not yet recruiting	Opioid Use Disorders, Cannabis Use	100	United States	clinicaltrials.gov
June 16, 2026	NCT07649278	The ENHANCE Project Toolkit	University of Wisconsin, Madison	Not applicable	Recruiting	Substance Related Disorder, Drug Overdose, eHealth	40	United States	clinicaltrials.gov
June 10, 2026	NCT07637994	Improving Jail Response to the Overdose Crisis: A Hybrid Trial of Jail ECHO to Improve MOUD Implementation and Public Health Outcomes	University of Massachusetts, Worcester	Not applicable	Recruiting	Opioid Abuse (Disorder)	100	United States	clinicaltrials.gov
June 8, 2026	NCT07632053	Postpartum Intervention for Mothers With Opioid Use Disorders (R33)	Stony Brook University	Not applicable	Recruiting	Opioid Use Disorder, Parent-Child Relations	80	United States	clinicaltrials.gov
June 8, 2026	NCT07631598	Buprenorphine Implementation at Syringe Service Programs to Reduce Overdoses	Montefiore Medical Center	Not applicable	Recruiting	Opioid Use Disorder, Opioid Use Disorder, Severe, Opioid Use Disorder, Moderate	512	United States	clinicaltrials.gov
June 8, 2026	NCT07631559	Pilot Study of an Adapted Partner Navigation Intervention Booster Session for Sustained Healthcare Engagement Among People Who Inject Drugs	University of California, San Francisco	Not applicable	Not yet recruiting	HEPATITIS C (HCV), Opioid Use Disorder, Substance Use Disorder (SUD), Drug Use Disorders, Healthcare Access, Harm...	50	United States	clinicaltrials.gov
June 5, 2026	NCT07630428	Testing STAR and TextSTAR: A Randomized Controlled Trial	University of Wisconsin, Madison	Not applicable	Enrolling by invitation	Sexual Violence, Posttraumatic Stress Disorder (PTSD), Opioid Misuse	394	United States	clinicaltrials.gov
June 2, 2026	NCT07620171	Peer Recovery Support for Opioid Use Disorder Treatment Retention	University of Pennsylvania	Not applicable	Enrolling by invitation	Opioid Use Disorder, Peer Recovery Supporters, Peer Recovery Coaching, Primary Care, Buprenorphine	15	United States	clinicaltrials.gov
May 28, 2026	NCT07610746	Cerebral Physiology of NOWS	Indiana University	Not applicable	Recruiting	Neonatal Opioid Withdrawal, Neonatal Opioid Withdrawal Syndrome, Opioid Use Disorder, Intrauterine Exposure	46	United States	clinicaltrials.gov
May 26, 2026	NCT07607743	Behavioral Optimization for Overcoming Suboptimal Treatment Retention (BUP-BOOSTeR)	Boston University	Not applicable	Not yet recruiting	Opioid Use Disorder	240		clinicaltrials.gov
May 22, 2026	NCT07602335	Safety, Tolerability, and Pharmacokinetics of MCAM in Healthy Adult Participants	The University of Texas Health Science Center at San Antonio	Early phase 1	Not yet recruiting	Opioid Use Disorder	24	United States	clinicaltrials.gov
May 22, 2026	NCT07602218	Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 2	Yale University	Not applicable	Completed	Opioid Use Disorder, Clinical Decision Support	379	United States	clinicaltrials.gov
May 20, 2026	NCT07600307	Evaluating a Digital Toolkit for IPV	Medical University of South Carolina	Not applicable	Not yet recruiting	Opioid Use Disorder	792		clinicaltrials.gov
May 19, 2026	NCT07594717	Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder	Prisma Health-Upstate	Observational	Completed	Nicotine Use Disoder, Opioid Use Disorder	70	United States	clinicaltrials.gov
May 14, 2026	NCT07587359	A Unique, Co-Designed Family-Based Therapy	Ohio State University	Not applicable	Recruiting	Opioid Abuse (Disorder)	120	United States	clinicaltrials.gov
May 14, 2026	NCT07586917	Optimizing Pregnancy and Treatment Interventions for Moms 3.0	University of Utah	Not applicable	Recruiting	Opioid Abuse (Disorder), Stimulant Use Disorders	429	United States	clinicaltrials.gov
May 6, 2026	NCT07569211	Simplified HCV Integrated Management Model in Methadone Clinics in Ukraine	Ukrainian Institute on Public Health Policy	Not applicable	Completed	HCV, Opioid Use Disorder	616	Ukraine	clinicaltrials.gov
May 6, 2026	NCT07568847	Improving Hospital-To-Methadone Clinic Connection Using Implementation Support for Patients With Opioid Use Disorder	University of Colorado, Denver	Not applicable	Not yet recruiting	Opioid Use Disorder	1,440		clinicaltrials.gov
April 30, 2026	NCT07558187	Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants	University of Thessaly	Observational	Recruiting	Non-communicable Diseases (NCD), Addiction to Opioids, Incarceration, Opioid-use Disorders	2,000	Greece	clinicaltrials.gov
April 23, 2026	NCT07549126	Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 1	Yale University	Not applicable	Completed	Opioid Use Disorder, Clinical Decision Support	267	United States	clinicaltrials.gov
April 22, 2026	NCT07546396	Methadone Rapid Restart	Pouya Azar	Phase 4	Not yet recruiting	Opioid Use Disorder	25	Canada	clinicaltrials.gov
April 21, 2026	NCT07541417	Building Retention and Initiation Through Delivery of Peer-Guided Evidence-Based Practices	Prisma Health-Upstate	Not applicable	Recruiting	Opioid Use Disorder	750	United States	clinicaltrials.gov
April 13, 2026	NCT07524738	Telemedicine XR-B for Individuals in Jail	Friends Research Institute, Inc.	Phase 3	Active not recruiting	Opioid Use Disorder	30	United States	clinicaltrials.gov
March 27, 2026	NCT07498322	Chicago Data-driven Opioid Use Disorder Screening, Engagement, Treatment and Planning System	University of Illinois Chicago	Not applicable	Not yet recruiting	Opiod Use Disorder	271,031	United States	clinicaltrials.gov
March 24, 2026	NCT07490717	Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails	University of Arkansas	Not applicable	Enrolling by invitation	Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use...	338	United States	clinicaltrials.gov
March 20, 2026	NCT07485335	A Bundled Intervention to End Opioid Overdoses	University of Alabama at Birmingham	Phase 4	Recruiting	Opioid Use Disorder, Opioid Overdose	160	United States	clinicaltrials.gov
March 16, 2026	NCT07475728	EMS-Initiated Buprenorphine	Yale University	Observational	Recruiting	Opioid Use Disorder	495	United States	clinicaltrials.gov
March 13, 2026	NCT07469501	Comparing Outpatient Treatment Retention Among Individuals Using Fentanyl Randomized to Low-dose and Direct-to-inject Buprenorphine...	University of California, San Francisco	Phase 4	Not yet recruiting	Opioid Use Disorder, Fentanyl	50	United States	clinicaltrials.gov
March 12, 2026	NCT07466784	CEDRN: Opioid Registry	University of British Columbia	Observational	Recruiting	Opioid Use Disorder, Opioid Abuse or Dependence, Opioid Withdrawal, Polysubstance Drug Use (Indiscriminate Drug Use)...	7,200	Canada	clinicaltrials.gov
March 9, 2026	NCT07457489	Vanderbilt Integrated Community TMS for Opioid Recovery	Vanderbilt University Medical Center	Not applicable	Recruiting	Opiod Use Disorder	100	United States	clinicaltrials.gov
March 9, 2026	NCT07456930	Real-World Evaluation of Compl-AI for Predicting Early Medication Dropout in Opioid Use Disorder Treatment	Tools4Patient	Observational	Not yet recruiting	Opioid Use Disorder	295	United States	clinicaltrials.gov
March 5, 2026	NCT07451197	Family-Focused Study to Support Medication for Opioid Use Disorder	University of Wisconsin, Madison	Not applicable	Not yet recruiting	Opioid Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe	338	United States	clinicaltrials.gov
February 27, 2026	NCT07439783	Testing the CrOss Systems Technical Assistance for Retaining Staff (COSTARS) Model for Improving Staff Retention Among Child Welfare...	Alicia Bunger	Not applicable	Enrolling by invitation	Substance Use Disorder, Opioid Use Disorder, Child Maltreatment, Implementation, Peer Recovery Supporters	200	United States	clinicaltrials.gov
February 27, 2026	NCT07439549	Symptom-Inhibited Naloxone Induction (SINI) for Buprenorphine Initiation: A Feasibility Trial	Pouya Azar	Phase 4	Recruiting	Opioid Use Disorder	12	Canada	clinicaltrials.gov
February 27, 2026	NCT07435077	Examining Analgesic Synergy and Efficacy in Trauma Care	Wake Forest University Health Sciences	Phase 4	Not yet recruiting	Opioid Use Disorder	282	United States	clinicaltrials.gov
February 19, 2026	NCT07421102	Pilot of Mailing Buprenorphine	Medical University of South Carolina	Early phase 1	Recruiting	Opioid Use Disorder	20	United States	clinicaltrials.gov
February 19, 2026	NCT07420283	A Study of Brenipatide in Participants With Opioid Use Disorder	Eli Lilly and Company	Phase 2	Recruiting	Opioid Use Disorder	465	Canada, Puerto Rico, United Kingdom, United States	clinicaltrials.gov
February 13, 2026	NCT07408193	The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.	National and Kapodistrian University of Athens	Early phase 1	Recruiting	Opioid-Refractory Chronic Cancer-Related Pain	24	Greece	clinicaltrials.gov
January 27, 2026	NCT07369089	Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement	University of California, San Diego	Phase 2	Recruiting	Opioid Use Disorder	88	United States	clinicaltrials.gov
January 23, 2026	NCT07362082	A Clinical Trial of Telehealth Treatment for Opioid Use Disorders	Yale University	Not applicable	Recruiting	Opioid Use Disorder	470	United States	clinicaltrials.gov
January 23, 2026	NCT07361731	Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use...	Arizona State University	Not applicable	Completed	Autonomic Nervous System Imbalance, Heart Rate Variability (HRV), Opioid Use Disorder, Breathing Techniques, Opioid...	32	United States	clinicaltrials.gov
January 23, 2026	NCT07361432	Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine	VA Office of Research and Development	Phase 3	Not yet recruiting	Opioid Use Disorder, Chronic Pain	250	United States	clinicaltrials.gov
January 20, 2026	NCT07350148	Opioid Adherence and Support Through Innovative Texting Strategies	University of New Mexico	Not applicable	Recruiting	Opioid Use Disorder (OUD), Chronic Pain	60	United States	clinicaltrials.gov
January 16, 2026	NCT07348796	Real World Evaluation of the Effectiveness and Implementation of a Digital Health Therapeutic for OUD	The University of Texas Health Science Center at San Antonio	Not applicable	Not yet recruiting	Opioid Use Disorder	134	United States	clinicaltrials.gov
January 15, 2026	NCT07344233	Neurofeedback During Naturalistic Stimuli to Reduce Craving in Heroin Addiction	Icahn School of Medicine at Mount Sinai	Not applicable	Completed	Opioid Use Disorder, Substance Use Disorder, Heroin Use Disorder	28	United States	clinicaltrials.gov
January 15, 2026	NCT07342504	Better Experiences in Substance Treatment: A Brief Alcohol-focused Intervention Tailored for Patients in Opioid Agonist Treatment	University of Notre Dame	Not applicable	Recruiting	Alcohol Use Disorder, Opioid Use Disorder, Alcohol Use, Opioid Use	60	United States	clinicaltrials.gov
January 8, 2026	NCT07325279	Nalmefene Implant in Healthy Subjects	ReacX Pharmaceuticals, Inc.	Phase 1	Recruiting	Opioid Abuse and Addiction	24	United States	clinicaltrials.gov
January 7, 2026	NCT07322588	Reentry Incentives and Support for Engagement With Contingency Management	Oregon Health and Science University	Not applicable	Not yet recruiting	Opioid Use Disorder	75	United States	clinicaltrials.gov
January 6, 2026	NCT07318480	Transcranial Direct Current Stimulation (tDCS) for Treatment of Substance Use Disorder	Icahn School of Medicine at Mount Sinai	Not applicable	Recruiting	Cocaine Use Disorder, Cocaine Dependence, Substance Use Disorder (SUD), Opioid Use Disorder, Opioid Dependence	240	United States	clinicaltrials.gov
December 19, 2025	NCT07294118	Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage	The University of Texas Medical Branch, Galveston	Phase 2	Recruiting	Subarachnoid Hemorrhage, Aneurysmal, Headache, Opiate Dependence, Opioid Use	15	United States	clinicaltrials.gov
December 12, 2025	NCT07278518	Evaluation of a Patient Decision Aid for Emergency Department Initiated Buprenorphine	Medical University of South Carolina	Not applicable	Recruiting	Opioid Use Disorder	20	United States	clinicaltrials.gov
December 8, 2025	NCT07269873	Safety and PK Study of BICX104 With or Without Bupropion Compared to Vivitrol	BioCorRx Pharmaceuticals Inc	Phase 1	Recruiting	Healthy Adult Male and Female Volunteers	30	United States	clinicaltrials.gov
December 3, 2025	NCT07262190	NavSTAR Implementation Effectiveness Trial Across a Health System	Friends Research Institute, Inc.	Not applicable	Recruiting	Opioid Use Disorder	720	United States	clinicaltrials.gov
November 18, 2025	NCT07232641	Impact of Federal and State Medications for Opioid Use Disorder (MOUD) Policy Changes During the Pandemic	Boston University	Observational	Recruiting	Substance Use Disorders, Alcohol Use Disorder, Opioid Use Disorder	185,810	United States	clinicaltrials.gov
November 10, 2025	NCT07226570	Mapping Ibogaine Neural Dynamics in Opioid Use Disorder	University of California, Irvine	Observational	Recruiting	Opioid Use Disorder (OUD)	20	United States	clinicaltrials.gov
October 28, 2025	NCT07221786	Preoperative Opioid Tapering Before Spine Surgery	Thomas Jefferson University	Not applicable	Recruiting	Opioid Consumption, Postoperative, Pain After Surgery, Opioid Dependency	45	United States	clinicaltrials.gov
October 20, 2025	NCT07218562	PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R61 Phase Pilot)	Chestnut Health Systems	Phase 2	Completed	Burnout, Compassion Satisfaction, Secondary Trauma	18	United States	clinicaltrials.gov
October 15, 2025	NCT07216963	The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study	Duke University	Not applicable	Not yet recruiting	Opioid Use Disorder, Overdose, Drug, Overdose, Substance Use (Drugs, Alcohol)	400	United States	clinicaltrials.gov
October 9, 2025	NCT07214467	Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder	University of California, San Francisco	Not applicable	Recruiting	Substance Use Disorder (SUD), Opioid Use Disorder (OUD)	6	United States	clinicaltrials.gov
October 9, 2025	NCT07214389	PRoducing Outcome Measures for OTP Quality Improvement	RTI International	Not applicable	Recruiting	Opioid Use Disorder	4,500	United States	clinicaltrials.gov
October 8, 2025	NCT07211399	Transition From Acute to Chronic Opioid Use and Chronic Pain	Jacques E. Chelly	Early phase 1	Withdrawn	Opioid Use Disorder	0	United States	clinicaltrials.gov
October 6, 2025	NCT07208266	Contingency Management for Opioid Use Disorder in Inpatients at Assiut University Hospital	Assiut University	Not applicable	Not yet recruiting	Opioid Use Disorder (OUD)	55		clinicaltrials.gov
October 2, 2025	NCT07204171	Phase 1 Study of Oral MG001	National Institute on Drug Abuse (NIDA)	Phase 1	Not yet recruiting	Safety and Tolerability in Healthy Subjects	32	United States	clinicaltrials.gov
October 1, 2025	NCT07202039	Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine	Prisma Health-Upstate	Not applicable	Recruiting	Tobacco-flavored EC, Sweet-Cooling EC, Sweet Non-cooling EC	90	United States	clinicaltrials.gov
September 29, 2025	NCT07197801	Evaluation of a Peer Recovery Support Program Adapted to Target Retention in Clinic-based Medication for Opioid Use Disorder Treatment	Geisinger Clinic	Not applicable	Recruiting	Opioid Use Disorder	218	United States	clinicaltrials.gov
September 18, 2025	NCT07179614	Kentucky Women's Justice Community Overdose Innovation Network - Phase II	Michele Staton	Not applicable	Recruiting	Overdose Risk, Opioid Use Disorder, Stimulant Use Disorders	300	United States	clinicaltrials.gov
September 17, 2025	NCT07178990	Mobile Platform for Optimizing Wellness and Engagement in Recovery	University of Michigan	Not applicable	Active not recruiting	Opioid Agonist Treatment, Alcohol Use Disorder, Opioid Use Disorder	50	United States	clinicaltrials.gov
September 16, 2025	NCT07176351	Acceptability and Feasibility of Extended-Release Subcutaneous Buprenorphine on a Mobile Pharmacy Clinic	Yale University	Phase 4	Recruiting	Opioid Use Disorder	60	United States	clinicaltrials.gov
September 12, 2025	NCT07171359	TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD)	Washington State University	Not applicable	Recruiting	Alcohol Use Disorder, Opioid Use Disorder	60	United States	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Yale University	12	October 21, 2026
University of Pittsburgh	6	July 20, 2025
Medical University of South Carolina	5	May 20, 2026
Ohio State University	4	October 26, 2026
Chestnut Health Systems	4	October 21, 2026
University of California, San Francisco	4	June 8, 2026
University of Pennsylvania	4	June 2, 2026
University of Maryland, Baltimore	4	September 3, 2025
Johns Hopkins University	3	October 28, 2026
Duke University	3	September 9, 2026
University of Michigan	3	August 31, 2026
Friends Research Institute, Inc.	3	August 26, 2026
University of Wisconsin, Madison	3	June 16, 2026
Montefiore Medical Center	3	June 8, 2026
Prisma Health-Upstate	3	May 19, 2026
University of Alabama at Birmingham	3	March 20, 2026
Icahn School of Medicine at Mount Sinai	3	January 15, 2026
University of Utah	2	October 8, 2026
University of Kentucky	2	September 25, 2026
Vanderbilt University Medical Center	2	September 24, 2026

By phase

Phase	New trials	Latest
Not applicable	116	October 28, 2026
Observational	15	October 15, 2026
Phase 2	13	October 15, 2026
Phase 1	12	September 2, 2026
Phase 4	12	August 6, 2026
Early phase 1	8	October 26, 2026
Phase 3	5	October 14, 2026
Phase 1/2	2	October 13, 2026

By country

Country	New trials	Latest
United States	160	October 28, 2026
Canada	5	July 24, 2026
Greece	3	April 30, 2026
Turkey (Türkiye)	2	May 13, 2025
Switzerland	1	August 21, 2026
Taiwan	1	July 29, 2026
Ukraine	1	May 6, 2026
Puerto Rico	1	February 19, 2026
United Kingdom	1	February 19, 2026
France	1	July 25, 2025
South Korea	1	July 22, 2025
China	1	June 11, 2025
Spain	1	May 9, 2025

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.