Data / New clinical trials / Glioblastoma

New Glioblastoma clinical trials: 226 posted since Nov 2024

Name: New Glioblastoma clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Glioblastoma clinical trials: 226 rows for $11.30, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 10 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/glioblastoma, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated October 30, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

226 clinical studies in glioblastoma were first posted on ClinicalTrials.gov from November 12, 2024 to October 30, 2026; 49 have an industry sponsor and 200 are recruiting or about to. The newest, NCT07908147, was posted on October 30, 2026: Biomarker-guided RAdiation-deferring Treatment in Younger GBM Patients - Pilot Study (Olivia Newton-John Cancer Research Institute).

The request: Every new Glioblastoma clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

226New trials
49Industry sponsored
200Recruiting or not yet
October 30, 2026Latest posted

Newest trials

The newest 100 of 226, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
October 30, 2026	NCT07908147	Biomarker-guided RAdiation-deferring Treatment in Younger GBM Patients - Pilot Study	Olivia Newton-John Cancer Research Institute	Early phase 1	Not yet recruiting	IDH Wildtype Glioblastoma, Glioblastoma (GBM)	12	Australia	clinicaltrials.gov
October 28, 2026	NCT07902037	A Study of SRN-101 Gene Therapy in Adults With Recurrent High-Grade Glioma (ALERT-1)	Siren Biotechnology	Phase 1/2	Not yet recruiting	Recurrent High Grade Gliomas, Glioblastoma (GBM), Astrocytoma, Oligodendroglioma, Diffuse Hemispheric Glioma	40		clinicaltrials.gov
October 22, 2026	NCT07888647	IDH1-vac in Patients With Newly Diagnosed IDH1R132H-positive High-grade Astrocytomas	German Cancer Research Center	Phase 2	Not yet recruiting	Astrocytoma, IDH-Mutant, Grade 3, Astrocytoma, IDH-Mutant, Grade 4	216	Germany	clinicaltrials.gov
October 20, 2026	NCT07884344	Window of Opportunity Study of Lixumistat in Patients With Newly Diagnosed Glioblastoma	Macarena De La Fuente, MD	Early phase 1	Recruiting	Glioblastoma	10	United States	clinicaltrials.gov
October 14, 2026	NCT07873996	Tris-CAR-T Cell Therapy Targeting CD44 and CD133 in Newly Diagnosed Glioblastoma	Beijing Tiantan Hospital	Phase 2/3	Not yet recruiting	Newly Diagnosed Glioblastoma, IDH-wildtype	60	China	clinicaltrials.gov
October 9, 2026	NCT07867886	An Optimization Study Evaluating Safety and Efficacy of the Y-90 Glioblastoma (GBM) Device in Patients With Recurrent GBM	Boston Scientific Corporation	Not applicable	Not yet recruiting	Recurrent Glioblastoma	30	France, Germany, Netherlands, Spain	clinicaltrials.gov
October 8, 2026	NCT07865195	Diffuse Gliomas in Reunion Island: Establishment of an Epidemiological, Clinical-biological and Socio-anthropological Cohorte	Centre Hospitalier Universitaire de la Réunion	Observational	Recruiting	Glioblastoma	214	Reunion	clinicaltrials.gov
October 7, 2026	NCT07862647	TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly Glioma	Alpheus Medical, Inc.	Phase 1	Recruiting	Glioblastom WHO Grade 4, GBM, bGBM, Butterfly GBM, Bihemispheric GBM, Glioblastoma	30	United States	clinicaltrials.gov
October 5, 2026	NCT07859059	Metronomic Temozolomide With Dexbrompheniramine for Recurrent High-Grade Glioma/Glioblastoma	University of Nebraska	Phase 1/2	Not yet recruiting	High Grade Glioma, Glioblastoma, Gliosarcoma	41	United States	clinicaltrials.gov
October 1, 2026	NCT07852975	GLAD-KE GLioma Biomarker and Safety Assessment During Dietary Ketone Elevation Subtitle: A Surgical Biomarker Discovery Study of Ketogenic...	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Not applicable	Not yet recruiting	Recurrent Glioma (Glioblastoma Multiforme)	20	United States	clinicaltrials.gov
September 22, 2026	NCT07832734	Metabolomics and Transcriptomics of Low- and High-Grade Gliomas	I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio	Observational	Recruiting	IDH Wildtype Glioblastoma, IDH Mutant Lower-Grade Gliomas	220	Italy	clinicaltrials.gov
September 22, 2026	NCT07832448	Microsurgical Resection Combined With Photodynamic Therapy for Recurrent Glioblastoma	Yonggao Mou	Not applicable	Active not recruiting	Recurrent Glioblastoma (WHO-Grade IV Glioma)	10	China	clinicaltrials.gov
September 21, 2026	NCT07831772	REMIND Maintenance Radiotherapy for Newly Diagnosed Glioblastoma	University of Minnesota	Not applicable	Recruiting	Glioblastoma, Newly Diagnosed Glioblastoma, Brain Tumor	4	United States	clinicaltrials.gov
September 21, 2026	NCT07831369	VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent Glioma	Inova Health Care Services	Phase 2	Recruiting	Glioblastoma, Astrocytoma, IDH-Mutant, Grade 4	52	United States	clinicaltrials.gov
September 21, 2026	NCT07831187	Entacapone Plus Bevacizumab for Glioblastoma at First Recurrence	First Affiliated Hospital of Wenzhou Medical University	Phase 1/2	Not yet recruiting	Glioblastoma	96	China	clinicaltrials.gov
September 21, 2026	NCT07831161	Safety and Efficacy of Autologous Natural Killer Cell Therapy (CHANK-101) in Patients With Recurrent Glioblastoma	Dong-A University Hospital	Not applicable	Not yet recruiting	Recurrent Glioblastoma	60	South Korea	clinicaltrials.gov
September 15, 2026	NCT07821112	Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile®	University of California, Irvine	Phase 2	Not yet recruiting	Glioma, Glioblastoma, GBM, Glioma, Malignant, Astrocytoma, Oligodendroglioma, Elderly Glioblastoma, Elderly GBM	20	United States	clinicaltrials.gov
September 10, 2026	NCT07811297	A Study of Catequentinib Hydrochloride (AL3818) in Endometrial, LGSOC, STS or GBM Cancers	Advenchen Pharmaceuticals, LLC.	Phase 1/2	Not yet recruiting	Endometrial Neoplasms, Ovarian Neoplasms, Soft Tissue Sarcoma (STS), Glioblastoma	138	United States	clinicaltrials.gov
August 27, 2026	NCT07791264	FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma	City of Hope Medical Center	Phase 1	Not yet recruiting	Glioblastoma, Malignant Glioma, Recurrent Glioblastoma, Recurrent Malignant Glioma	24	United States	clinicaltrials.gov
August 27, 2026	NCT07789379	Adebrelimab Plus Temozolomide ± Hyperbaric Oxygen for Primary Glioblastoma	Wei Jiang	Phase 2	Not yet recruiting	Glioblastoma	94		clinicaltrials.gov
August 26, 2026	NCT07788430	Impact of Pesticide Exposure on Survival and Tumor Aggressiveness in Patients With Glioblastoma: A Prospective Clinical Study	Institut Claudius Regaud	Not applicable	Not yet recruiting	Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype	120	France	clinicaltrials.gov
August 24, 2026	NCT07781852	Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer	Lumina Pharmaceuticals Inc	Early phase 1	Not yet recruiting	Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer, Colorectal Cancer, Esophageal Cancer, Gastric Cancer (GC)...	40	United States	clinicaltrials.gov
August 21, 2026	NCT07778602	Safety and Feasibility of First-line Avutometinib and Defactinib in Patients With Newly Diagnosed High-grade Gliomas	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Early phase 1	Not yet recruiting	MGMT-unmethylated Glioblastoma (GBM), IDH Wildtype Glioblastoma	22	Puerto Rico, United States	clinicaltrials.gov
August 20, 2026	NCT07775534	Tear Fluid for the Detection of Tumor-associated Extracellular Vesicles in Glioblastoma Patients	City of Hope Medical Center	Not applicable	Recruiting	Glioblastoma	30	United States	clinicaltrials.gov
August 18, 2026	NCT07769918	Hypoxia-targeted Radiotherapy Boost for GBM	NYU Langone Health	Not applicable	Not yet recruiting	Glioblastoma (GBM)	25	United States	clinicaltrials.gov
August 13, 2026	NCT07762716	Combination Immunotherapy Treatment for Glioblastoma Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient)...	BreakBio Corp	Phase 1/2	Not yet recruiting	Glioblastoma (GBM)	10	United States	clinicaltrials.gov
August 11, 2026	NCT07758062	Levetiracetam Extended-Release Plus Stupp Protocol for Hypoxic IDH-Wildtype Glioblastoma	Tianjin Medical University General Hospital	Phase 2	Not yet recruiting	Glioblastoma	140	China	clinicaltrials.gov
August 10, 2026	NCT07754734	STUPP Regimen With or Without Lenvatinib for Newly Diagnosed Glioblastoma With MGMT Promoter Methylation	Dongguan People's Hospital	Phase 2	Not yet recruiting	Glioma, Glioblastoma (GBM), MGMT-Methylated Glioblastoma	138		clinicaltrials.gov
August 7, 2026	NCT07751744	Phase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal...	Jubilant Therapeutics Inc.	Phase 1/2	Not yet recruiting	Brain Metastases From Solid Tumors, Leptomeningeal Disease, High Grade Glioma (HGG), Glioblastoma (GBM)	113		clinicaltrials.gov
August 5, 2026	NCT07748299	NuvOx Expanded Access	NuvOx LLC	Not applicable	Available	Glioblastoma, Respiratory Distress Syndrom, Ischemic Stroke, Hypoxic Conditions	Not listed		clinicaltrials.gov
July 31, 2026	NCT07739017	OLIG2 Inhibitor CT-179 for Recurrent and Newly-diagnosed Glioblastoma	Olivia Newton-John Cancer Research Institute	Phase 1	Not yet recruiting	Recurrent Glioblastoma, Newly Diagnosed MGMT Unmethylated Glioblastoma	54	Australia	clinicaltrials.gov
July 30, 2026	NCT07735819	Positron Emission Tomography/Computed Tomography (PET/CT) Imaging in Patients Diagnosed With a Glioma	Barbara Ann Karmanos Cancer Institute	Phase 2	Not yet recruiting	Low Grade Glioma, Glioblastoma	61	United States	clinicaltrials.gov
July 29, 2026	NCT07733674	Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma...	Radiomedix, Inc.	Phase 1	Recruiting	Glioblastoma Multiforme (GBM), Pancreatic Ductal Adenocarcinoma (PDAC)	20	United States	clinicaltrials.gov
July 28, 2026	NCT07731555	Characterization of the Blood-Brain Barrier in High-Grade Glioma Through Immunohistochemical, Transcriptional, Fluorescein and Radiological...	Patrick Morris	Not applicable	Recruiting	Glioblastoma	100	Ireland	clinicaltrials.gov
July 20, 2026	NCT07715097	Survivin-Targeted Dendritic Cell (DC) Cell Injection for Newly Diagnosed Glioblastoma	Beijing Tricision Biotherapeutics Inc	Phase 2	Not yet recruiting	Glioblastoma	30		clinicaltrials.gov
July 17, 2026	NCT07712770	Pilot Radioembolisation Clinical Trial Assessing Safety and Efficacy in Recurrent Glioma	Olivia Newton-John Cancer Research Institute	Early phase 1	Not yet recruiting	Recurrent Glioblastoma IDH Wildtype, Recurrent Glioblastoma	12	Australia	clinicaltrials.gov
July 16, 2026	NCT07708961	Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma	Mayo Clinic	Phase 2	Recruiting	Glioblastoma, IDH-Wildtype	60	United States	clinicaltrials.gov
July 8, 2026	NCT07689721	ctDNA-Guided Intraventricular Therapy for CNS Malignancies	Alireza Mansouri	Not applicable	Not yet recruiting	Leptomeningeal Disease, Glioblastoma, Brain Metastases, Non-Small Cell Lung Cancer, Breast Cancer	77		clinicaltrials.gov
July 1, 2026	NCT07678138	Exploratory Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of Tumor Neoantigen-pulsed Autologous Dendritic...	Huanhu Hospital Affiliated to Tianjin Medical University	Not applicable	Not yet recruiting	Glioblastoma	9		clinicaltrials.gov
June 29, 2026	NCT07674095	Assessment of a Large US EHR Database as Meeting FDA Fit-for-Purpose Requirements to Provide External Controls for Study BPM31510 in...	BPGbio	Observational	Active not recruiting	Glioblastoma	150	United States	clinicaltrials.gov
June 29, 2026	NCT07673679	GliomaAI-Astro4: MRI-Based Detection of IDH Mutant Astrocytoma Grade 4	Deep Learning Institute of Radiological Sciences	Observational	Completed	Glioma, Glioma (Diagnosis), Astrocytoma, Astrocytoma, Grade IV, Astrocytoma, IDH-Mutant, Grade 4	1,372	India	clinicaltrials.gov
June 26, 2026	NCT07670455	Brain Radiotherapy Imaging for High-grade Glioma Using Hypoxia Targeting Through Oxygen-Enhanced Response	The Leeds Teaching Hospitals NHS Trust	Not applicable	Not yet recruiting	High Grade Gliomas, Hypoxia Brain, Glioblastoma (GBM), Brain Neoplasms, Adult	25		clinicaltrials.gov
June 25, 2026	NCT07670026	Intensified Adjuvant Therapy for High-Risk Newly Diagnosed Glioblastoma With Subtotal Resection or Short-Term Progression	Second Affiliated Hospital, Zhejiang University, School of Medicine	Phase 2	Recruiting	Glioblastoma	31	China	clinicaltrials.gov
June 25, 2026	NCT07668869	TTFields Plus FET-PET-Guided Stereotactic Radiosurgery Versus TTFields Alone for Recurrent Glioblastoma (Tarrget 2.0)	Prof. Franciszek Lukaszczyk Memorial Oncology Center	Not applicable	Recruiting	Glioblastoma, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype, Glioblastoma Multiforme, Adult	92	Poland	clinicaltrials.gov
June 24, 2026	NCT07664579	Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against...	City of Hope Medical Center	Observational	Recruiting	Anatomic Stage IV Breast Cancer AJCC v8, Glioblastoma, Lung Carcinoma, Malignant Solid Neoplasm, Metastatic Breast...	160	United States	clinicaltrials.gov
June 16, 2026	NCT07651020	The Clinical Application Value of SPECT Imaging Targeting LRRC15 in Malignant Tumors	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Observational	Completed	Pancreatic Cancer, Breast Cancer, Lung Cancer, Sarcoma, Head and Neck Cancers, Glioblastoma, Colorectal Cancer...	1	China	clinicaltrials.gov
June 15, 2026	NCT07648823	Dosimetry, Safety, and Efficacy Study of [177Lu]Lu-XT771 in Patients With Recurrent Glioblastoma	Beijing Tiantan Hospital	Early phase 1	Recruiting	Recurrent Glioblastoma (WHO-Grade IV Glioma), Recurrent Glioblastoma, Glioblastoma (GBM), Recurrent Glioblastoma IDH...	5	China	clinicaltrials.gov
June 12, 2026	NCT07643870	Human ADME Study of [14C]-AZD1390	AstraZeneca	Phase 1	Not yet recruiting	Advanced Solid Malignancies	8	United Kingdom	clinicaltrials.gov
June 9, 2026	NCT07636200	The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer	University of Colorado, Boulder	Not applicable	Recruiting	Advanced Solid Tumor Cancer, Stage IV Cancer (Solid Tumors Only), Glioblastoma, Stage III Ovarian Cancer, Small Cell...	250	United States	clinicaltrials.gov
June 9, 2026	NCT07635173	SM-1 Combined With Temozolomide in Subjects With Refractory or Recurrent High-Grade Gliomas	Shenzhen Zhenxing Medical Technology Co., Ltd	Phase 1	Completed	Glioma, Glioblastomas (GBM), High Grade Gliomas	35	China	clinicaltrials.gov
June 9, 2026	NCT07634575	Triggered Imaging in Glioblastoma Based on Clinical Outcome Evaluation Compared to Routine: a Feasibility Study	King's College Hospital NHS Trust	Not applicable	Enrolling by invitation	Glioblastoma	20	United Kingdom	clinicaltrials.gov
June 5, 2026	NCT07628647	Living Well With Brain Cancer: A Group-Based Intervention to Promote Whole-Person Well-Being	University of Colorado, Denver	Not applicable	Recruiting	Brain Cancer	64	United States	clinicaltrials.gov
June 4, 2026	NCT07628257	Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of DTI and Rs-fMRI to a Preoperative FDG PET Strategy, With...	Centre Paul Strauss	Not applicable	Not yet recruiting	Glioblastoma	80	France	clinicaltrials.gov
June 4, 2026	NCT07627334	Personalized Targeted Glioblastoma Therapies by ex Vivo Drug Screening: Advanced Brain Tumor TheRApy Clinical Trial In Patients Scheduled...	Medical University of Vienna	Not applicable	Recruiting	Glioblastoma (GBM)	30	Austria	clinicaltrials.gov
June 2, 2026	NCT07620548	Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas	Washington University School of Medicine	Phase 2	Not yet recruiting	Glioblastoma, Glioblastoma, IDH-wildtype, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype	99	United States	clinicaltrials.gov
June 1, 2026	NCT07616986	LITT for Ultra-early GBM Recurrence	Insel Gruppe AG, University Hospital Bern	Not applicable	Recruiting	Glioblastoma (GBM), Glioblastoma - Category	12	Switzerland	clinicaltrials.gov
May 27, 2026	NCT07608003	Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:	Xiangya Hospital of Central South University	Observational	Recruiting	Gliomas Harboring IDH1 and/or IDH2 Mutations, Glioma Glioblastoma Multiforme, Glioma of Brainstem, Glioma, Diffuse...	500	China	clinicaltrials.gov
May 22, 2026	NCT07604285	A Phase 1/2 Study of Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated Glioblastoma	Myosin Therapeutics Inc.	Phase 1/2	Not yet recruiting	Glioblastoma	36	United States	clinicaltrials.gov
May 15, 2026	NCT07590726	PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors	Copenhagen University Hospital, Rigshospitalet	Not applicable	Not yet recruiting	Brain Injuries, Acute, Brain Tumor Adult, Brain (Nervous System) Cancers, Traumatic Brain Injuries, Glioblastom WHO...	160	Denmark	clinicaltrials.gov
May 14, 2026	NCT07585851	Administration of Repurposed Ketoconazole in Glioma Patients	Universitas Padjadjaran	Early phase 1	Active not recruiting	Diffuse Glioma, Diffuse Glioma, Grade I, Diffuse Glioma, Grade II, Diffuse Glioma, Grade III, Diffuse Glioma, Grade IV	80	Indonesia	clinicaltrials.gov
May 12, 2026	NCT07579208	A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor...	M.D. Anderson Cancer Center	Phase 1	Recruiting	Phase 1, NK Cell, IL13Ra, EGFRvIII, Chimera Antigen Receptor (CAR), NR3C1, Recurrent Glioblastoma	36	United States	clinicaltrials.gov
May 6, 2026	NCT07568782	Impact of Fluorescence-Guided Resection and Chemoradiotherapy on the Systemic Immune Response in Glioblastoma: A Kinetic Analysis of Immune...	University Hospital, Lille	Observational	Not yet recruiting	Glioblastoma	17	France	clinicaltrials.gov
May 5, 2026	NCT07567196	PET-Guided Resection in High-Grade Gliomas	Universita degli Studi di Genova	Observational	Recruiting	Glioma Glioblastoma Multiforme, Glioma, High Grade, Glioma Surgery, Positron-Emission Tomography(PET)	100	Italy	clinicaltrials.gov
May 1, 2026	NCT07560865	First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma	Masonic Cancer Center, University of Minnesota	Phase 1	Recruiting	Astrocytoma, Glioblastoma, Progressive Disease	9	United States	clinicaltrials.gov
April 28, 2026	NCT07553520	Dietary Cysteine and Methionine Deprivation (CMD) in Glioma Patients	UNC Lineberger Comprehensive Cancer Center	Not applicable	Withdrawn	Glioblastoma Multiforme, Recurrent Glioma	0	United States	clinicaltrials.gov
April 27, 2026	NCT07552467	Sub-topic Four: Clinical Translation of Original Radioactive Drugs for Precision Diagnosis and Treatment of Gastrointestinal Tumors...	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Observational	Recruiting	Pancreatic Cancer, Breast Cancer, Lung Cancer, Sarcoma, Head and Neck Tumors, Glioblastoma, Colorectal Cancer, Melanoma	26	China	clinicaltrials.gov
April 27, 2026	NCT07552233	NK Cell Therapy for Malignant Solid Brain Tumors	Peking University Third Hospital	Not applicable	Recruiting	Malignant Solid Brain Tumors, Glioblastoma (GBM), Glioblastoma Multiforme (GBM), Brain Metastasis, Malignant Meningioma	27	China	clinicaltrials.gov
April 24, 2026	NCT07551336	Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma	Beijing Biotech	Phase 1	Recruiting	Malignant Glioma, High-Grade Gliomas, Glioblastoma, Recurrent High-Grade Gliomas, Recurrent Glioblastoma	36	China	clinicaltrials.gov
April 23, 2026	NCT07546669	Efficacy of Zoster Vaccination in Glioblastoma Patients	University Hospital, Essen	Phase 4	Not yet recruiting	Glioblastoma (GBM)	230		clinicaltrials.gov
April 22, 2026	NCT07544992	Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive...	City of Hope Medical Center	Phase 1	Recruiting	Recurrent Astrocytoma, IDH-Mutant, Grade 4, Recurrent Glioblastoma, IDH-Wildtype	24	United States	clinicaltrials.gov
April 21, 2026	NCT07541781	Sitagliptin in Recurrent/Progressive Grade 4 Glioma	Kailin Yang, MD, PhD	Phase 1	Recruiting	Glioma, Glioblastoma, Recurrent Glioma, Recurrent Glioblastoma, Grade 4 Malignant Glioma of Brain (Disorder)	45	United States	clinicaltrials.gov
April 20, 2026	NCT07538128	Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent...	Huashan Hospital	Early phase 1	Recruiting	Recurrent Glioblastoma	10	China	clinicaltrials.gov
April 15, 2026	NCT07532031	APT-weighted and Diffusion MRI for Characterizing Tumor Infiltration in High-Grade Gliomas	IRCCS Ospedale San Raffaele	Observational	Not yet recruiting	High-Grade Glioma, Glioblastoma, Brain Tumor Adult	20		clinicaltrials.gov
April 13, 2026	NCT07524140	A First-in-Human Study of ZE94-0605 in Patients With Advanced Solid Tumors	Eilean Therapeutics	Phase 1	Recruiting	Advanced Solid Tumor Cancer, Metastatic Solid Tumor	60	Australia, Uzbekistan	clinicaltrials.gov
April 13, 2026	NCT07523529	Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors	Beijing Biotech	Phase 1/2	Recruiting	Advanced Unresectable, Metastatic	72	China	clinicaltrials.gov
April 13, 2026	NCT07521657	Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma	University of Alabama at Birmingham	Phase 2	Not yet recruiting	Neurofibromatosis 1 (NF1)	55	United States	clinicaltrials.gov
April 7, 2026	NCT07515924	Oral Gallium Maltolate for Recurrent Glioblastoma	Medical College of Wisconsin	Early phase 1	Not yet recruiting	Glioblastoma	8	United States	clinicaltrials.gov
April 6, 2026	NCT07512154	Precision Radiotherapy Enabled by Molecular MRI	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Not applicable	Recruiting	Brain Cancer	20	United States	clinicaltrials.gov
April 6, 2026	NCT07511725	Prophylactic Regimen With Intrathecal Thiotepa in SVZ-positive or Meningeal-risk Glioblastoma	Second Affiliated Hospital, Zhejiang University, School of Medicine	Phase 2	Recruiting	Glioblastoma (GBM)	38	China	clinicaltrials.gov
March 30, 2026	NCT07501559	A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of JL15003 Injection in Patients With Recurrent Glioblastoma (rGBM)	Jecho Biopharmaceuticals Co., Ltd.	Phase 1/2	Recruiting	Recurrent Glioblastoma Multiforme(GBM)	40	China	clinicaltrials.gov
March 30, 2026	NCT07499141	Use of Fluorescence in Gliomas	Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria	Observational	Completed	High Grade Glioma, Glioblastoma, Brain Neoplasms	41	Italy	clinicaltrials.gov
March 27, 2026	NCT07497373	A Phase I Study to Evaluate the Safety and Tolerability of JL15003 Injection in Patients With Recurrent Glioblastoma	Jecho Biopharmaceuticals Co., Ltd.	Phase 1	Completed	Recurrent Glioblastoma Multiforme(GBM)	17	China	clinicaltrials.gov
March 25, 2026	NCT07493447	Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures	Eben Rosenthal	Early phase 1	Recruiting	Meningioma, Glioblastoma, Acoustic Neuroma, Brain Cancer, Pituitary Adenoma	30	United States	clinicaltrials.gov
March 25, 2026	NCT07492836	Hypofractionated Radiotherapy Plus Temozolamide in Patients Younger Than 70 Years With Glioblastoma	Hospital do Coracao	Not applicable	Not yet recruiting	Glioblastoma (GBM)	10		clinicaltrials.gov
March 23, 2026	NCT07488754	Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) In Newly Diagnosed Glioma (WHO G3-G4)	Medical University of Warsaw	Not applicable	Recruiting	Glioblastoma, High-Grade Glioma (WHO III-IV), Glioblastoma (GBM)	35	Poland	clinicaltrials.gov
March 20, 2026	NCT07485049	BGB-58067 in Newly Diagnosed Glioblastoma Patients With MTAP-Deleted Tumors	Nader Sanai	Early phase 1	Recruiting	Glioblastoma (GBM)	78	United States	clinicaltrials.gov
March 18, 2026	NCT07480941	Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma	Beijing Biotech	Phase 1	Recruiting	Glioblastoma, High-grade Glioma, Malignant Glioma, Recurrent Glioblastoma, Recurrent High-grade Glioma	36	China	clinicaltrials.gov
March 17, 2026	NCT07476794	Daily Temozolomide for Elderly Patients With Unmethylated MGMT- Promoter Newly Diagnosed GliOblatoma	Sunnybrook Health Sciences Centre	Phase 2	Recruiting	Glioblastoma	118	Canada	clinicaltrials.gov
March 16, 2026	NCT07472387	Impact of Androgen Signaling on the Composition of the Immune Microenvironment in Glioblastomas	Assistance Publique - Hôpitaux de Paris	Not applicable	Not yet recruiting	Glioblastoma (GBM)	40	France	clinicaltrials.gov
March 12, 2026	NCT07468136	Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas	Mayo Clinic	Phase 1/2	Recruiting	Anaplastic Oligodendroglioma, Astrocytoma, IDH-Mutant, Grade 3, Astrocytoma, IDH-Mutant, Grade 4, Diffuse Astrocytoma...	33	United States	clinicaltrials.gov
March 11, 2026	NCT07464925	A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma	Tetragon Biosciences Ltd	Phase 1	Recruiting	Glioblastoma Multiforme of Brain, Glioma, Glioblastoma	30	United States	clinicaltrials.gov
March 10, 2026	NCT07462507	Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1	Washington University School of Medicine	Phase 2	Recruiting	Central Nervous System Cancer, Brain Metastases	104	United States	clinicaltrials.gov
March 10, 2026	NCT07461948	Advanced Imaging Techniques for Evaluating the Tumor Immune Microenvironment in Glioblastoma Patients	Jonsson Comprehensive Cancer Center	Phase 3	Recruiting	Glioblastoma	15	United States	clinicaltrials.gov
March 9, 2026	NCT07459101	UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-4	Sunnybrook Health Sciences Centre	Not applicable	Recruiting	Glioblastoma (GBM), Astrocytoma, Grade IV	120	Canada	clinicaltrials.gov
March 6, 2026	NCT07455045	A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)	Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.	Phase 1	Not yet recruiting	High Grade Glioma (III or IV), Diffuse Midline Glioma (DMG), Glioblastoma (GBM)	40	China	clinicaltrials.gov
March 5, 2026	NCT07452458	Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype...	NRG Oncology	Phase 3	Recruiting	Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma	398	United States	clinicaltrials.gov
March 4, 2026	NCT07448480	Comprehensive Analysis of Chemotherapy and Targeted Therapy Outcomes in Recurrent Malignant Gliomas	Blokhin's Russian Cancer Research Center	Observational	Active not recruiting	Recurrent Malignant Glioma, Glioblastoma, Anaplastic Astrocytoma, Pleomorphic Xanthoastrocytoma	1,000	Russia	clinicaltrials.gov
March 2, 2026	NCT07443176	FCI-Glioblastoma Study	University of Aberdeen	Observational	Not yet recruiting	Glioblastom WHO Grade 4	18	United Kingdom	clinicaltrials.gov
February 27, 2026	NCT07439172	Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma.	Cooper Norcross Health	Phase 2	Recruiting	High Grade Gliomas, Glioblastoma, Astrocytoma, Oligodendroglioma	70	United States	clinicaltrials.gov
February 24, 2026	NCT07431216	A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of STAR-001 (LP-184) in Combination With...	Starlight Therapeutics Inc.	Phase 1/2	Not yet recruiting	Glioblastoma (GBM)	68		clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Mayo Clinic	8	July 16, 2026
Second Affiliated Hospital, Zhejiang University, School of Medicine	6	June 25, 2026
City of Hope Medical Center	5	August 27, 2026
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	4	October 1, 2026
Washington University School of Medicine	4	June 2, 2026
Medical University of Warsaw	4	March 23, 2026
Olivia Newton-John Cancer Research Institute	3	October 30, 2026
Copenhagen University Hospital, Rigshospitalet	3	May 15, 2026
Beijing Biotech	3	April 24, 2026
Sunnybrook Health Sciences Centre	3	March 17, 2026
Beijing Tiantan Hospital	2	October 14, 2026
Alpheus Medical, Inc.	2	October 7, 2026
NuvOx LLC	2	August 5, 2026
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	2	June 16, 2026
Myosin Therapeutics Inc.	2	May 22, 2026
Peking University Third Hospital	2	April 27, 2026
University Hospital, Essen	2	April 23, 2026
Huashan Hospital	2	April 20, 2026
Jecho Biopharmaceuticals Co., Ltd.	2	March 30, 2026
Nader Sanai	2	March 20, 2026

By phase

Phase	New trials	Latest
Not applicable	54	October 9, 2026
Phase 1	43	October 7, 2026
Phase 2	40	October 22, 2026
Observational	33	October 8, 2026
Phase 1/2	28	October 28, 2026
Early phase 1	19	October 30, 2026
Phase 3	6	March 10, 2026
Phase 2/3	2	October 14, 2026
Phase 4	1	April 23, 2026

By country

Country	New trials	Latest
United States	86	October 20, 2026
China	40	October 14, 2026
France	11	October 9, 2026
United Kingdom	10	June 12, 2026
Australia	8	October 30, 2026
Italy	7	September 22, 2026
Germany	6	October 22, 2026
Switzerland	6	June 1, 2026
Poland	5	June 25, 2026
Denmark	5	May 15, 2026
Belgium	5	August 13, 2025
Netherlands	4	October 9, 2026
Canada	4	March 17, 2026
Spain	3	October 9, 2026
South Korea	3	September 21, 2026
Sweden	3	January 23, 2026
Ireland	2	July 28, 2026
Austria	2	June 4, 2026
Russia	2	March 4, 2026
Singapore	2	April 6, 2025
Reunion	1	October 8, 2026
Puerto Rico	1	August 21, 2026
India	1	June 29, 2026
Indonesia	1	May 14, 2026
Uzbekistan	1	April 13, 2026

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.