Data / Nonprofits / South Carolina / Charleston / Human services
Human services nonprofits in Charleston, SC: 99 registered with the IRS
99 human services nonprofits are registered with the IRS in Charleston, SC, 99 of them 501(c)(3) charities; the 48 that report revenue took in $182.1 million. The largest by revenue: Bishop Gadsden Episcopal Retirement Community ($83.5 million), Palmetto Goodwill ($65.1 million), Charleston County Human Services Commission ($11.6 million).
SpecStream is the live web data engine for teams and agents. It reads the IRS register of exempt organizations as the IRS updates it, and this page is that reading. Ask for the nonprofits you need by place, cause and size, with their latest Form 990 figures and websites, and they arrive in your sheet, CRM, Slack or agent.
Every organization, largest by revenue first
| Organization | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|
| Bishop Gadsden Episcopal Retirement Community | 501(c)(3) | 1943 | $83.5 million | $387.5 million | 2025-12 |
| Palmetto Goodwill | 501(c)(3) | 2015 | $65.1 million | $137.2 million | 2024-12 |
| Charleston County Human Services Commission | 501(c)(3) | 1986 | $11.6 million | $6.5 million | 2024-12 |
| Wings for Kids | 501(c)(3) | 1996 | $4 million | $3 million | 2025-06 |
| Drayton Hall Preservation Trust | 501(c)(3) | 2015 | $3.2 million | $6.3 million | 2025-06 |
| Florence Crittenton Programs of South Carolina Inc | 501(c)(3) | 1945 | $2.9 million | $4 million | 2025-06 |
| James Island Presbyterian Foundation | 501(c)(3) | 1985 | $1.6 million | $2.2 million | 2025-06 |
| Coastal District Council of the St Vincent de Paul Society Diocese of | 501(c)(3) | 2003 | $1.4 million | $439,322 | 2024-12 |
| Lowcountry Orphan Relief | 501(c)(3) | 2007 | $1.3 million | $3.9 million | 2025-12 |
| Charleston Recovery Center Inc | 501(c)(3) | 2010 | $932,598 | $869,650 | 2025-12 |
| Fosters Child Care & Dev Center Inc | 501(c)(3) | 1993 | $908,350 | $3,908 | 2024-12 |
| YWCA of Greater Charleston | 501(c)(3) | 1971 | $797,303 | $11.7 million | 2025-06 |
| Respite Care of Charleston | 501(c)(3) | 2011 | $576,222 | $563,825 | 2025-12 |
| Jewish Family Services of Greater Charleston | 501(c)(3) | 2021 | $551,864 | $686,899 | 2025-12 |
| Hope and Health Akot South Sudan | 501(c)(3) | 2025 | $442,276 | $55,868 | 2025-12 |
| Trident Urban League Inc | 501(c)(3) | 1992 | $402,789 | $238,451 | 2025-12 |
| Ebenezer Social Action & Community Development Enterprise | 501(c)(3) | 2002 | $359,020 | $2 million | 2025-05 |
| Greystar Giving Inc | 501(c)(3) | 2010 | $325,210 | $7,116 | 2024-12 |
| Next Child Fund Inc | 501(c)(3) | 2007 | $289,371 | $4.9 million | 2026-03 |
| Teachers Supply Closet | 501(c)(3) | 2007 | $225,365 | $103,310 | 2025-12 |
| This Is Noteworthy | 501(c)(3) | 2015 | $198,881 | $199,016 | 2024-12 |
| Fields To Families | 501(c)(3) | 2007 | $183,729 | $127,916 | 2024-12 |
| Post Partum Support Charleston | 501(c)(3) | 2011 | $177,883 | $52,896 | 2025-06 |
| Phoebe Pember Foundation | 501(c)(3) | 2004 | $172,202 | $133,954 | 2024-12 |
| Family Resource Center for Disabili Disabilities and Special Needs Inc | 501(c)(3) | 2001 | $167,724 | $4,050 | 2024-12 |
| Youth Empowerment Services Inc | 501(c)(3) | 2000 | $134,360 | $36,551 | 2024-12 |
| Peninsula Biblical Counseling Ministries | 501(c)(3) | 2015 | $120,562 | $120,899 | 2025-12 |
| Second Chance Bikes | 501(c)(3) | 2018 | $119,501 | $67,475 | 2024-12 |
| Charleston Mens Chorus Inc | 501(c)(3) | 1998 | $77,803 | $183,684 | 2025-06 |
| Lowcountry Warrior Moms | 501(c)(3) | 2017 | $57,814 | $25,758 | 2025-12 |
| Soldiers of Hope Inc | 501(c)(3) | 2024 | $57,523 | $21,587 | 2025-12 |
| Robert Bosch Fair Share Fund | 501(c)(3) | 2025 | $45,642 | $69,169 | 2025-12 |
| Homeless To Hope Center | 501(c)(3) | 2023 | $38,516 | $74,959 | 2025-12 |
| Reid House of Christian Service | 501(c)(3) | 1971 | $36,696 | $458,428 | 2024-12 |
| Charleston Tibetan Society Inc | 501(c)(3) | 1996 | $32,909 | $275,775 | 2025-12 |
| Heal With Hearts | 501(c)(3) | 2014 | $32,835 | $9,857 | 2025-12 |
| Abundantly More Childrens Closet | 501(c)(3) | 2024 | $29,785 | $12,728 | 2025-12 |
| Twenty Pearls Foundation of Charleston Inc | 501(c)(3) | 2006 | $22,389 | $16,113 | 2024-12 |
| Lowcountry Senior Coalition | 501(c)(3) | 1998 | $22,283 | $122,518 | 2025-12 |
| The Mission Collective Inc | 501(c)(3) | 2006 | $12,752 | $82,903 | 2025-12 |
| Brooks Haven Management Corporation | 501(c)(3) | 2020 | $11,524 | $68,116 | 2025-12 |
| You Keep Hope Alive | 501(c)(3) | 2023 | $8,418 | $3,172 | 2023-12 |
| St James Foundation | 501(c)(3) | 1999 | $7,478 | $856,500 | 2025-12 |
| Gift of Life of Rotary District 7770 Inc | 501(c)(3) | 1998 | $5,988 | $276,318 | 2023-06 |
| Spanish America | 501(c)(3) | 2022 | $4,301 | $76,575 | 2025-08 |
| Jonathan Edward Irvin Foundation | 501(c)(3) | 2022 | $4,003 | $110,435 | 2025-12 |
| Joint Services Support Corporation | 501(c)(3) | 2012 | $2,900 | $14,937 | 2025-12 |
| Hart Learning Academy Inc | 501(c)(3) | 2022 | $750 | $11,040 | 2025-12 |
| A Centralized Moment - the Focus Is You | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| A Longer Table | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| All Things Fresh Inc | 501(c)(3) | 2024 | |||
| Altruistic Souls | 501(c)(3) | 2026 | |||
| Ame-Global Missions | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Ampersand Initiative Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| And Initiative | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Beautybundle | 501(c)(3) | 2024 | |||
| Big Cahoonas Trust | 501(c)(3) | 2025 | |||
| Bless Our Heart | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Boots-2-Heels South Carolina Chapter | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Carius Foundation Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Charleston County Adult Drug Court Foundation | 501(c)(3) | 2007 | $0 | $0 | 2025-12 |
| Conflict Resolution for Kids | 501(c)(3) | 2025 | $0 | $0 | 2025-09 |
| Dove Fund | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Eft Charleston Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Empowered Destiny Inc | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| F3 Friendship Fashion and Freedom Women Empowerment Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Families for Fertility | 501(c)(3) | 2014 | $0 | $0 | 2024-12 |
| First Baptist Churchfoundation of James Island | 501(c)(3) | 2010 | $0 | $0 | 2023-12 |
| First Families of South Carolina 1670-1700 | 501(c)(3) | 1982 | $0 | $0 | 2025-12 |
| For the People By the People Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Friends of Watoto-Us | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Frohman Foundation- Discovery and Care | 501(c)(3) | 2024 | $8,974 | 2023-12 | |
| Gift & Ed | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Greenville Qmmunity Center Inc | 501(c)(3) | 2026 | |||
| Harleston Senior Village | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Harlows Hope | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Helping India Missions | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Husser Financial Services | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| I Got Legs | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Lamour A La Croix | 501(c)(3) | 2024 | |||
| Le Fortunate | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Lowcountry Herald | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Mad Park | 501(c)(3) | 2021 | $0 | $21,667 | 2025-12 |
| On Solid Grounds | 501(c)(3) | 1999 | $1 | 2023-12 | |
| Operation 58 Inc | 501(c)(3) | 2024 | |||
| Pay It Forward Charleston | 501(c)(3) | 2020 | $0 | $0 | 2024-12 |
| Port City Bridge Builder Foundation | 501(c)(3) | 2024 | |||
| Precepts Outreach Inc | 501(c)(3) | 2001 | $0 | $0 | 2025-12 |
| Real Talk - Real Action - Real Results | 501(c)(3) | 2011 | $0 | $0 | 2025-12 |
| Sean Patrick Lisbon Heart Initiative | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Septima P Clark Corporation | 501(c)(3) | 2011 | $0 | $0 | 2025-12 |
| Servants Heart Network | 501(c)(3) | 2025 | $0 | $0 | 2025-08 |
| Service Before Self Foundation | 501(c)(3) | 2018 | $0 | $0 | 2024-12 |
| Sexual Health Awareness Sti Prevention & Education Initiative | 501(c)(3) | 2022 | $0 | $0 | 2025-04 |
| Summers Domestic Violence Foundation Inc | 501(c)(3) | 2021 | $0 | $0 | 2023-12 |
| The Way There and Back Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Vera May Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Word of Life Ministries West Inc | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Yeamans Hall Foundation | 501(c)(3) | 2025 | $0 | $1 | 2025-04 |
Other causes in Charleston, SC
- Education 149
- Religion-related 104
- Arts, culture and humanities 101
- Philanthropy, voluntarism and grantmaking foundations 95
- Recreation and sports 73
- Community improvement and capacity building 70
- Health care 42
- Housing and shelter 28
- Environment 28
- Youth development 26
- Public and societal benefit 26
- Animal-related 23
- Mental health and crisis intervention 23
- Diseases, disorders and medical disciplines 16
- International, foreign affairs and national security 15
- Food, agriculture and nutrition 14
- Mutual and membership benefit 10
- Science and technology 9
- Medical research 9
- Employment 8
- Public safety, disaster preparedness and relief 8
- Civil rights, social action and advocacy 8
- Crime and legal-related 6
Every nonprofit in Charleston, SC · Human services nonprofits across the state · Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.