Data / Nonprofits / South Carolina / Charleston / Health care
Health care nonprofits in Charleston, SC: 42 registered with the IRS
42 health care nonprofits are registered with the IRS in Charleston, SC, 42 of them 501(c)(3) charities; the 20 that report revenue took in $1.29 billion. The largest by revenue: Bon Secours-St Francis Xavier Hospital Inc ($620.6 million), Roper Hospital Inc ($539.5 million), Musc Health Partners ($49.4 million).
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Every organization, largest by revenue first
| Organization | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|
| Bon Secours-St Francis Xavier Hospital Inc | 501(c)(3) | 1998 | $620.6 million | $319 million | 2024-12 |
| Roper Hospital Inc | 501(c)(3) | 1955 | $539.5 million | $343.1 million | 2024-12 |
| Musc Health Partners | 501(c)(3) | 2020 | $49.4 million | $9.1 million | 2025-06 |
| Musc Health | 501(c)(3) | 2017 | $24.6 million | $119.9 million | 2025-06 |
| Medical Society of S C | 501(c)(3) | 1979 | $17.7 million | $701.6 million | 2024-12 |
| Mainsail Health Partners | 501(c)(3) | 2020 | $15.1 million | $207.1 million | 2025-06 |
| Ronald McDonald House Charleston | 501(c)(3) | 1982 | $12.1 million | $33.4 million | 2025-12 |
| STC Healthcare Partners Risk Retention Group | 501(c)(3) | 2022 | $4.7 million | $24 million | 2025-12 |
| Allied Services Risk Retention Group | 501(c)(3) | 2005 | $2 million | $8 million | 2024-12 |
| The Palmetto Palace | 501(c)(3) | 2007 | $510,577 | $30,877 | 2025-12 |
| Lowcountry Veterans Home | 501(c)(3) | 2019 | $485,383 | $656,025 | 2026-01 |
| Friends of Fisher House Charleston Inc | 501(c)(3) | 2013 | $432,814 | $861,789 | 2025-12 |
| Comprehensive Psychiatric Care Specialists | 501(c)(3) | 2015 | $182,490 | $69,809 | 2025-06 |
| Lets Walk | 501(c)(3) | 2022 | $149,464 | $76,721 | 2025-12 |
| Hoofprints in the Sand Inc | 501(c)(3) | 2023 | $144,369 | $18,607 | 2024-12 |
| Islands Against Cancer Inc | 501(c)(3) | 2022 | $85,653 | $32,717 | 2025-12 |
| Pro-Life Charleston | 501(c)(3) | 2017 | $66,171 | $44,728 | 2025-06 |
| T O Missions Worldwide Inc | 501(c)(3) | 2024 | $34,740 | $22,683 | 2024-12 |
| Hammer Out Pediatric Cancer Corp | 501(c)(3) | 2019 | $25,569 | $1 | 2023-12 |
| Disaster Anesthesia Inc | 501(c)(3) | 2025 | $20,397 | $4,163 | 2025-12 |
| American Art Therapy Association Inc | 501(c)(3) | 1996 | $0 | $0 | 2025-12 |
| Bradens Butterflies Inc | 501(c)(3) | 2016 | $0 | $0 | 2025-09 |
| Breaking Ribbons | 501(c)(3) | 2026 | |||
| Breathe Clear Foundation | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Cancer Relief Fund | 501(c)(3) | 2016 | $0 | $0 | 2025-06 |
| Carolina Chapter National Association of Diversity Officers | 501(c)(3) | 2023 | $0 | $0 | 2024-06 |
| Carolina Ehealth Alliance | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Carolina Family Care Inc | 501(c)(3) | 2026 | |||
| Fetter Better Care Foundation | 501(c)(3) | 2026 | |||
| Gary Ostroski Sr Foundation Inc | 501(c)(3) | 2024 | |||
| Healthy Lifestyle Network | 501(c)(3) | 2007 | $0 | $0 | 2025-12 |
| Jeans Fund of SC Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Medical University Hospital Authority | 501(c)(3) | 2004 | 2025-06 | ||
| Medical University Hospital Imaging Center | 501(c)(3) | 2022 | |||
| Monka Foundation | 501(c)(3) | 2022 | $5,671 | 2025-12 | |
| Morris Street Baptist Church Outreach Program | 501(c)(3) | 2003 | |||
| PH Spe I Inc | 501(c)(3) | 2026 | |||
| Santas Families | 501(c)(3) | 2023 | $6,106 | 2025-12 | |
| Talbot Charitable Trust | 501(c)(3) | 2026 | |||
| The Randall Heffron Foundation Trust | 501(c)(3) | 2014 | $610 | 2025-12 | |
| Trident Head Injury Support Group | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| University Medical Associates of the Medical Univ of South Carolina | 501(c)(3) | 1991 | 2025-06 |
Other causes in Charleston, SC
- Education 149
- Religion-related 104
- Arts, culture and humanities 101
- Human services 99
- Philanthropy, voluntarism and grantmaking foundations 95
- Recreation and sports 73
- Community improvement and capacity building 70
- Housing and shelter 28
- Environment 28
- Youth development 26
- Public and societal benefit 26
- Animal-related 23
- Mental health and crisis intervention 23
- Diseases, disorders and medical disciplines 16
- International, foreign affairs and national security 15
- Food, agriculture and nutrition 14
- Mutual and membership benefit 10
- Science and technology 9
- Medical research 9
- Employment 8
- Public safety, disaster preparedness and relief 8
- Civil rights, social action and advocacy 8
- Crime and legal-related 6
Every nonprofit in Charleston, SC · Health care nonprofits across the state · Nonprofits in every city of the state
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.