Data / Drug companies / Acetaminophen, aspirin, caffeine

Acetaminophen, aspirin, caffeine: 48 companies and 90 products in the FDA NDC directory

Updated November 6, 2026. Source: US Food and Drug Administration, National Drug Code Directory (openFDA).

Acetaminophen, aspirin, caffeine is listed in the FDA National Drug Code Directory by 48 companies, with 90 products in commercial distribution. 28 of the products (31.1%) are marketed under an abbreviated new drug application (ANDA), the generic route. The most common dosage forms are tablet, film coated; tablet; tablet, coated, and the newest product started marketing on October 30, 2026.

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Companies listing it

48

Products

90

Generic (ANDA) products

28 (31.1%)

Application numbers

4

Routes

Oral

Brand names

Headache Relief Extra Strength, Headache Relief, Migraine Relief, Good Sense Migraine Formula, Migraine Formula, Extra Strength Headache Relief, Basic Care Migraine Relief, Medique Pain Off

openFDA record search

api.fda.gov

Companies that list acetaminophen, aspirin, caffeine

Ranked by number of products. Finished drugs in commercial distribution.

Dosage forms

Marketing categories

Pharmacologic classes

CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.