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Data / Drug companies / Central Nervous System Stimulant

Central Nervous System Stimulant drugs: 92 drugs from 241 companies in the FDA NDC directory

Central Nervous System Stimulant is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 1,390 products in this class from 241 companies, covering 92 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on October 30, 2026.

SpecStream is the live web data engine for teams and agents. It reads the National Drug Code Directory that FDA publishes, and this page is that reading. Ask for the companies that make a drug, a class or a dosage form, with their headquarters, website and size added from the web, and new listings and discontinued products arrive in your sheet, CRM, Slack or agent as FDA posts them.

  • 241Companies
  • 1,390Products
  • 92Drugs by generic name

Drugs in the Central Nervous System Stimulant class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Acetaminophen, aspirin, caffeine9048
Methylphenidate hydrochloride21139
Caffeine5138
Acetaminophen, caffeine, pyrilamine maleate3126
Acetaminophen, aspirin and caffeine2926
Butalbital, acetaminophen and caffeine3723
Butalbital, acetaminophen, and caffeine2622
Dexmethylphenidate hydrochloride11417
Dextroamphetamine sulfate5617
Lisdexamfetamine dimesylate14716
Acetaminophen, caffeine2014
Acetaminophen, aspirin, and caffeine2113
Amphetamine sulfate3012
Aspirin, caffeine1211
Aspirin and caffeine1510
Caffeine citrate158
Acetaminophen, caffeine, and pyrilamine maleate87
Methylphenidate235
Acetaminophen aspirin caffeine55
Acetaminophen, caffeine and pyrilamine maleate55
Butalbital, aspirin, and caffeine55
Amphetamine194
Acetaminophen, aspirin (nsaid), caffeine64
Butalbital, acetaminophen, caffeine and codeine phosphate54
Lisdexamfetamine193
Dextroamphetamine63
Orphenadrine citrate, aspirin and caffeine53
Acetaminophen and caffeine33
Aspirin, acetaminophen, caffeine33
Butalbital, aspirin, caffeine and codeine phosphate33
Ergotamine tartrate and caffeine33
Methamphetamine hydrochloride33
Anhydrous citric acid, aspirin, and sodium bicarbonate13
Acetaminophen, aspirin (nsaid), and caffeine52
Aspirin,caffeine42
Acetaminophen 250mg aspirin 250mg caffeine 65mg32
Acetaminophen, aspirin (nsaid) and caffeine32
Amphetamine sulfate tablets32
Butalbital, acetaminophen, caffeine, and codeine phosphate32
Acetaminophen and aspirin and caffeine22
Menstrual complete22
Pain reliever12
Caffeinum81
Lisdexamfetamine dimesylate capsules71
Amphetamine extended-release61
Lisdexamfetamine dimesylate oral51
5% minoxidil hair growth serum31
Methylphenidate extended-release31
Serdexmethylphenidate and dexmethylphenidate31
Acetaminophen , caffeine and pyrilamine maleate21
Acetaminophen, asprin, caffeine21
Acetaminophen, pyrilamine maleate, caffeine21
Acetaminophen/aspirin/caffeine tablet21
Aspirin/caffeine oral powder21
Methylphenidate hcl21
Methylphenidate hydrochloride extended release21
Tension headache relief21
5% minoxidil hair growth foam11
Acetaminophen , aspirin and caffeine11
Acetaminophen 250 mg aspirin 250 mg caffeine 65 mg11
Acetaminophen 250 mg, aspirin 250 mg, and caffeine 65 mg11
Acetaminophen 250mg, aspirin 250mg and caffeine 65mg11
Acetaminophen 500 mg with caffeine 65mg11
Acetaminophen 500mg caffeine 60mg pyrilamine maleate 15mg11
Acetaminophen, aspirin, caffeine tablet11
Acetaminophen, aspirin, caffeine tablet, film coated11
Acetaminophen, caffeine anhydrous,11
Acetaminophen, caffeine, and pyrilamine maleate tablet11
Acetaminophen, caffeine, aspirin tablet11
Acetaminophen, caffeine, dihydrocodeine bitartrate11
Acetaminophen,caffeine11
Acetaminophen-aspirin-caffeine11
Acetaminophen-caffeine11
Anhydrous citric acid, aspirin11
Anti-aging eye mask11
Aspirin. caffeine11
Asprin and caffeine11
Butal/apap/caff11
Butal/apap/caffeine11
Butalbital, acetaminophen, and caffeine capsules11
Butalbital, aspirin, cafeine, and codeine phosphate11
Butalbital/acetaminophen/caffeine11
Caffeine and sodium benzoate11
Caffeine tablet, film-coated11
Caffeine, acetaminophen, aspirin11
Caffeine, choline salicylate11
Caffeine, magnesium salicylate11
Caffine11
Conditioner11
Eye cream11
Midol complete11
Sham poo11

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
Bryant Ranch Prepack60tablet; capsule, extended releaseGeneric drugs (ANDA)May 3, 2024
Lannett Company, Inc.50capsule, extended release; capsuleGeneric drugs (ANDA)February 22, 2024
SpecGx LLC50capsule, extended release; tabletGeneric drugs (ANDA)December 17, 2024
Granules Pharmaceuticals Inc.45capsule, extended release; tabletGeneric drugs (ANDA)January 29, 2025
Camber Pharmaceuticals, Inc.44capsule, extended release; tabletGeneric drugs (ANDA)September 9, 2024
Bryant Ranch Prepack31tablet; capsule, extended releaseGeneric drugs (ANDA)July 30, 2020
Sun Pharmaceutical Industries, Inc.31tablet; capsuleGeneric drugs (ANDA)December 20, 2024
Sandoz Inc30capsule, extended release; capsuleAuthorized generics (NDA)October 1, 2026
Rhodes Pharmaceuticals LLC27capsule, extended release; tabletGeneric drugs (ANDA)January 30, 2024
Amneal Pharmaceuticals of New York LLC25capsule, extended release; capsuleGeneric drugs (ANDA)July 5, 2017
Teva Pharmaceuticals, Inc.23capsule; tablet, orally disintegratingGeneric drugs (ANDA)December 8, 2025
Walgreen Company21tablet; tablet, film coatedOver the counter monograph drugsMay 1, 2026
Elite Laboratories, Inc.20capsule; tabletGeneric drugs (ANDA)November 15, 2024
Opmx LLC17tablet, film coated; tabletOver the counter monograph drugsMarch 11, 2026
Lil' Drug Store Products, Inc.16tablet, film coated; tabletOver the counter monograph drugsAugust 1, 2023
Aurolife Pharma, LLC15tablet; capsuleGeneric drugs (ANDA)January 31, 2019
Bryant Ranch Prepack15tablet; capsuleGeneric drugs (ANDA)May 1, 2024
Azurity Pharmaceuticals, Inc.14tablet; solutionGeneric drugs (ANDA)March 20, 2026
Sandoz Inc14capsule, extended release; tabletNew drug applications (NDA)May 31, 2005
Golden State Medical Supply, Inc.13tablet, extended release; capsule, extended releaseGeneric drugs (ANDA)November 26, 2021
Haleon US Holdings LLC13tablet, film coated; tablet, coatedOver the counter monograph drugsJanuary 1, 2024
KVK-Tech, Inc.13tablet; solutionGeneric drugs (ANDA)September 26, 2018
Lupin Pharmaceuticals,Inc.13tablet; tablet, chewableGeneric drugs (ANDA)April 25, 2016
Solco Healthcare US, LLC13capsule; tabletGeneric drugs (ANDA)December 5, 2023
Takeda Pharmaceuticals America, Inc.13capsule; tablet, chewableNew drug applications (NDA)January 28, 2017
Alvogen Inc.12capsule; tabletGeneric drugs (ANDA)August 25, 2023
Medtech Products Inc.12powderOver the counter monograph drugsFebruary 2, 2026
NextWave Pharmaceuticals, Inc12suspension, extended release; tablet, extended releaseNew drug applications (NDA)November 4, 2021
NorthStar Rx LLC12tabletGeneric drugs (ANDA)March 20, 2019
Actavis Pharma, Inc.11capsule, extended release; capsuleGeneric drugs (ANDA)September 30, 2020
Mylan Pharmaceuticals Inc.11capsule; patchGeneric drugs (ANDA)August 25, 2023
American Health Packaging10capsule; tablet, extended releaseGeneric drugs (ANDA)December 24, 2025
Dolgencorp, Inc. (dollar General & Rexall)10tablet, film coated; tabletOver the counter monograph drugsFebruary 21, 2024
Hikma Pharmaceuticals USA Inc.10capsule; tabletGeneric drugs (ANDA)January 17, 2024
Sunrise Pharmaceutical, Inc.10tablet; capsuleGeneric drugs (ANDA)July 4, 2018
Takeda Pharmaceuticals America, Inc.10capsule, extended releaseNew drug applications (NDA)June 20, 2017
XLCare Pharmaceuticals, Inc.10tablet, extended release; tablet, chewableGeneric drugs (ANDA)February 26, 2020
Bayer HealthCare LLC.9tablet; powderOver the counter monograph drugsFebruary 5, 2026
Neos Therapeutics Brands, LLC9tablet, orally disintegratingNew drug applications (NDA)June 20, 2017
Neos Therapeutics, LP9tablet, orally disintegratingAuthorized generics (NDA)July 1, 2026
Teva Pharmaceuticals USA, Inc.9tabletGeneric drugs (ANDA)March 19, 2003
Ascend Laboratories, LLC8tablet; solutionGeneric drugs (ANDA)April 1, 2020
Cardinal Health 110, LLC. DBA Leader8tablet, film coated; tabletOver the counter monograph drugsOctober 30, 2026
Carolina Cannabis Creations LLC8chewable gelOver the counter monograph drugsNovember 14, 2025
Cranbury Pharmaceuticals, LLC8tablet; solutionGeneric drugs (ANDA)August 20, 2022
Dr. Reddy's Laboratories Inc.8capsule, extended release; tabletGeneric drugs (ANDA)September 25, 2026
Hahnemann Laboratories, Inc.8pelletUnapproved homeopathic productsMay 9, 2022
Kroger Company8tablet; tablet, film coatedOver the counter monograph drugsMay 5, 2025
Newton Laboratories, Inc.8liquid; pelletUnapproved homeopathic productsSeptember 25, 2023
Novartis Pharmaceuticals Corporation8capsule, extended releaseNew drug applications (NDA)May 31, 2005
Noven Therapeutics, LLC8patch, extended release; patchNew drug applications (NDA)May 15, 2023
Par Health USA, LLC8capsule, extended releaseGeneric drugs (ANDA)January 5, 2017
Rite Aid Corporation8tablet, film coated; tabletOver the counter monograph drugsSeptember 27, 2024
Teva Pharmaceuticals USA, Inc.8capsule, extended releaseGeneric drugs (ANDA)July 5, 2017
Apotex Corp.7capsuleGeneric drugs (ANDA)November 9, 2023
AvKARE7capsuleGeneric drugs (ANDA)June 4, 2025
CVS Pharmacy7tablet; tablet, film coatedOver the counter monograph drugsJuly 5, 2021
Epic Pharma, LLC7tabletGeneric drugs (ANDA)September 18, 2020
Prasco Laboratories7capsule, extended release; solutionAuthorized generics (NDA)May 15, 2014
Safeway7tablet; tablet, film coatedOver the counter monograph drugsApril 29, 2024
Teva Pharmaceuticals USA, Inc.7tabletGeneric drugs (ANDA)March 3, 2015
Trigen Laboratories, LLC7tablet, extended releaseGeneric drugs (ANDA)June 23, 2022
Vertical Pharmaceuticals, LLC7tablet, extended releaseNew drug applications (NDA)June 23, 2022
Wilshire Pharmaceuticals, Inc.7tabletGeneric drugs (ANDA)August 6, 2021
Winder Laboratories LLC7tabletGeneric drugs (ANDA)December 6, 2021
Actavis Pharma, Inc.6capsule, extended releaseGeneric drugs (ANDA)June 22, 2012
Amneal Pharmaceuticals LLC6capsuleGeneric drugs (ANDA)August 28, 2023
Ani Pharmaceuticals, Inc.6capsule, extended releaseGeneric drugs (ANDA)March 16, 2020
Aytu BioPharma, Inc.6capsule, extended releaseNew drug applications (NDA)February 22, 2024
Burel Pharmaceuticals, LLC6capsule, extended releaseGeneric drugs (ANDA)December 16, 2019
Novadoz Pharmaceuticals LLC6tablet, chewableGeneric drugs (ANDA)February 2, 2024
Oryza Pharmaceuticals Inc.6tabletGeneric drugs (ANDA)October 19, 2020
Target Corporation6tablet, film coated; tabletOver the counter monograph drugsApril 7, 2025
United Natural Foods, Inc. DBA Unfi6tablet, film coated; tabletOver the counter monograph drugsSeptember 3, 2024
Walmart Inc.6tablet, film coated; tabletOver the counter monograph drugsAugust 19, 2024
Allegiant Health5tablet, film coated; capsuleOver the counter monograph drugsNovember 5, 2024
Amazon.com Services LLC5tablet, film coatedGeneric drugs (ANDA)September 11, 2026
CVS Pharmacy5tablet, film coatedOver the counter monograph drugsMarch 13, 2008
Family Dollar (family Wellness)5tablet; tablet, film coatedOver the counter monograph drugsJanuary 25, 2024
Glenmark Pharmaceuticals Inc., USA5tabletGeneric drugs (ANDA)May 12, 2025
Ironshore Pharmaceuticals Inc.5capsuleNew drug applications (NDA)June 1, 2019
Kobayashi Healthcare International, Inc.5tablet, film coated; tablet, coatedOver the counter monograph drugsOctober 31, 2024
Navajo Manufacturing Company Inc.5tablet, film coated; tabletOver the counter monograph drugsMarch 13, 2025
Nivagen Pharmaceuticals, Inc.5tabletGeneric drugs (ANDA)May 3, 2024
Quagen Pharmaceuticals LLC5capsule; solutionGeneric drugs (ANDA)May 1, 2024
Actavis Pharma, Inc.4tablet, film coated, extended releaseGeneric drugs (ANDA)March 4, 2019
Advanced Rx of Tennessee, LLC4capsule; tabletGeneric drugs (ANDA)January 8, 2026
Chain Drug Marketing Association4tablet, film coated; powderOver the counter monograph drugsMarch 25, 2021
Chain Drug Marketing Association, Inc.4tablet, film coated; tabletOver the counter monograph drugsSeptember 2, 2025
Guangzhou Ariel Biotech Co., Ltd.4liquidOther unapproved drugsApril 2, 2026
Janssen Pharmaceuticals, Inc.4tablet, extended releaseNew drug applications (NDA)August 1, 2000
L.N.K. International, Inc.4tablet, film coated; tabletOver the counter monograph drugsJuly 19, 2023
LGM Pharma Solutions, LLC4capsule; tabletGeneric drugs (ANDA)October 18, 2021
Lannett Company, Inc.4tablet, extended releaseGeneric drugs (ANDA)September 23, 2013
Padagis US LLC4patchAuthorized generics (NDA)June 5, 2023
Pioneer Life Sciences, LLC4tabletOver the counter monograph drugsOctober 2, 2024
Sandoz Inc4tabletGeneric drugs (ANDA)June 14, 2002
Time Cap Laboratories, Inc4tablet, film coated; tabletOver the counter monograph drugsJune 16, 2021
Topco Associates LLC4tablet, film coatedOver the counter monograph drugsJune 16, 2022
Unifirst First Aid Corporation4tablet, film coatedOver the counter monograph drugsSeptember 26, 2022

Dosage forms

Dosage formProductsShare
Tablet44532%
Capsule, extended release26519.1%
Capsule19013.7%
Tablet, film coated16511.9%
Tablet, extended release594.2%
Tablet, chewable564%
Solution412.9%
Tablet, coated302.2%
Tablet, orally disintegrating241.7%
Powder231.7%
Liquid191.4%
Patch120.9%

Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.