Data / Drug companies / Central Nervous System Stimulant
Central Nervous System Stimulant drugs: 92 drugs from 241 companies in the FDA NDC directory
Central Nervous System Stimulant is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 1,390 products in this class from 241 companies, covering 92 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on October 30, 2026.
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- 241Companies
- 1,390Products
- 92Drugs by generic name
Drugs in the Central Nervous System Stimulant class
Ranked by number of companies that list the drug.
| Drug | Products here | Companies listing it |
|---|---|---|
| Acetaminophen, aspirin, caffeine | 90 | 48 |
| Methylphenidate hydrochloride | 211 | 39 |
| Caffeine | 51 | 38 |
| Acetaminophen, caffeine, pyrilamine maleate | 31 | 26 |
| Acetaminophen, aspirin and caffeine | 29 | 26 |
| Butalbital, acetaminophen and caffeine | 37 | 23 |
| Butalbital, acetaminophen, and caffeine | 26 | 22 |
| Dexmethylphenidate hydrochloride | 114 | 17 |
| Dextroamphetamine sulfate | 56 | 17 |
| Lisdexamfetamine dimesylate | 147 | 16 |
| Acetaminophen, caffeine | 20 | 14 |
| Acetaminophen, aspirin, and caffeine | 21 | 13 |
| Amphetamine sulfate | 30 | 12 |
| Aspirin, caffeine | 12 | 11 |
| Aspirin and caffeine | 15 | 10 |
| Caffeine citrate | 15 | 8 |
| Acetaminophen, caffeine, and pyrilamine maleate | 8 | 7 |
| Methylphenidate | 23 | 5 |
| Acetaminophen aspirin caffeine | 5 | 5 |
| Acetaminophen, caffeine and pyrilamine maleate | 5 | 5 |
| Butalbital, aspirin, and caffeine | 5 | 5 |
| Amphetamine | 19 | 4 |
| Acetaminophen, aspirin (nsaid), caffeine | 6 | 4 |
| Butalbital, acetaminophen, caffeine and codeine phosphate | 5 | 4 |
| Lisdexamfetamine | 19 | 3 |
| Dextroamphetamine | 6 | 3 |
| Orphenadrine citrate, aspirin and caffeine | 5 | 3 |
| Acetaminophen and caffeine | 3 | 3 |
| Aspirin, acetaminophen, caffeine | 3 | 3 |
| Butalbital, aspirin, caffeine and codeine phosphate | 3 | 3 |
| Ergotamine tartrate and caffeine | 3 | 3 |
| Methamphetamine hydrochloride | 3 | 3 |
| Anhydrous citric acid, aspirin, and sodium bicarbonate | 1 | 3 |
| Acetaminophen, aspirin (nsaid), and caffeine | 5 | 2 |
| Aspirin,caffeine | 4 | 2 |
| Acetaminophen 250mg aspirin 250mg caffeine 65mg | 3 | 2 |
| Acetaminophen, aspirin (nsaid) and caffeine | 3 | 2 |
| Amphetamine sulfate tablets | 3 | 2 |
| Butalbital, acetaminophen, caffeine, and codeine phosphate | 3 | 2 |
| Acetaminophen and aspirin and caffeine | 2 | 2 |
| Menstrual complete | 2 | 2 |
| Pain reliever | 1 | 2 |
| Caffeinum | 8 | 1 |
| Lisdexamfetamine dimesylate capsules | 7 | 1 |
| Amphetamine extended-release | 6 | 1 |
| Lisdexamfetamine dimesylate oral | 5 | 1 |
| 5% minoxidil hair growth serum | 3 | 1 |
| Methylphenidate extended-release | 3 | 1 |
| Serdexmethylphenidate and dexmethylphenidate | 3 | 1 |
| Acetaminophen , caffeine and pyrilamine maleate | 2 | 1 |
| Acetaminophen, asprin, caffeine | 2 | 1 |
| Acetaminophen, pyrilamine maleate, caffeine | 2 | 1 |
| Acetaminophen/aspirin/caffeine tablet | 2 | 1 |
| Aspirin/caffeine oral powder | 2 | 1 |
| Methylphenidate hcl | 2 | 1 |
| Methylphenidate hydrochloride extended release | 2 | 1 |
| Tension headache relief | 2 | 1 |
| 5% minoxidil hair growth foam | 1 | 1 |
| Acetaminophen , aspirin and caffeine | 1 | 1 |
| Acetaminophen 250 mg aspirin 250 mg caffeine 65 mg | 1 | 1 |
| Acetaminophen 250 mg, aspirin 250 mg, and caffeine 65 mg | 1 | 1 |
| Acetaminophen 250mg, aspirin 250mg and caffeine 65mg | 1 | 1 |
| Acetaminophen 500 mg with caffeine 65mg | 1 | 1 |
| Acetaminophen 500mg caffeine 60mg pyrilamine maleate 15mg | 1 | 1 |
| Acetaminophen, aspirin, caffeine tablet | 1 | 1 |
| Acetaminophen, aspirin, caffeine tablet, film coated | 1 | 1 |
| Acetaminophen, caffeine anhydrous, | 1 | 1 |
| Acetaminophen, caffeine, and pyrilamine maleate tablet | 1 | 1 |
| Acetaminophen, caffeine, aspirin tablet | 1 | 1 |
| Acetaminophen, caffeine, dihydrocodeine bitartrate | 1 | 1 |
| Acetaminophen,caffeine | 1 | 1 |
| Acetaminophen-aspirin-caffeine | 1 | 1 |
| Acetaminophen-caffeine | 1 | 1 |
| Anhydrous citric acid, aspirin | 1 | 1 |
| Anti-aging eye mask | 1 | 1 |
| Aspirin. caffeine | 1 | 1 |
| Asprin and caffeine | 1 | 1 |
| Butal/apap/caff | 1 | 1 |
| Butal/apap/caffeine | 1 | 1 |
| Butalbital, acetaminophen, and caffeine capsules | 1 | 1 |
| Butalbital, aspirin, cafeine, and codeine phosphate | 1 | 1 |
| Butalbital/acetaminophen/caffeine | 1 | 1 |
| Caffeine and sodium benzoate | 1 | 1 |
| Caffeine tablet, film-coated | 1 | 1 |
| Caffeine, acetaminophen, aspirin | 1 | 1 |
| Caffeine, choline salicylate | 1 | 1 |
| Caffeine, magnesium salicylate | 1 | 1 |
| Caffine | 1 | 1 |
| Conditioner | 1 | 1 |
| Eye cream | 1 | 1 |
| Midol complete | 1 | 1 |
| Sham poo | 1 | 1 |
Companies with the most products in this class
| Company | Products | Main dosage forms | Main marketing category | Newest product started |
|---|---|---|---|---|
| Bryant Ranch Prepack | 60 | tablet; capsule, extended release | Generic drugs (ANDA) | May 3, 2024 |
| Lannett Company, Inc. | 50 | capsule, extended release; capsule | Generic drugs (ANDA) | February 22, 2024 |
| SpecGx LLC | 50 | capsule, extended release; tablet | Generic drugs (ANDA) | December 17, 2024 |
| Granules Pharmaceuticals Inc. | 45 | capsule, extended release; tablet | Generic drugs (ANDA) | January 29, 2025 |
| Camber Pharmaceuticals, Inc. | 44 | capsule, extended release; tablet | Generic drugs (ANDA) | September 9, 2024 |
| Bryant Ranch Prepack | 31 | tablet; capsule, extended release | Generic drugs (ANDA) | July 30, 2020 |
| Sun Pharmaceutical Industries, Inc. | 31 | tablet; capsule | Generic drugs (ANDA) | December 20, 2024 |
| Sandoz Inc | 30 | capsule, extended release; capsule | Authorized generics (NDA) | October 1, 2026 |
| Rhodes Pharmaceuticals LLC | 27 | capsule, extended release; tablet | Generic drugs (ANDA) | January 30, 2024 |
| Amneal Pharmaceuticals of New York LLC | 25 | capsule, extended release; capsule | Generic drugs (ANDA) | July 5, 2017 |
| Teva Pharmaceuticals, Inc. | 23 | capsule; tablet, orally disintegrating | Generic drugs (ANDA) | December 8, 2025 |
| Walgreen Company | 21 | tablet; tablet, film coated | Over the counter monograph drugs | May 1, 2026 |
| Elite Laboratories, Inc. | 20 | capsule; tablet | Generic drugs (ANDA) | November 15, 2024 |
| Opmx LLC | 17 | tablet, film coated; tablet | Over the counter monograph drugs | March 11, 2026 |
| Lil' Drug Store Products, Inc. | 16 | tablet, film coated; tablet | Over the counter monograph drugs | August 1, 2023 |
| Aurolife Pharma, LLC | 15 | tablet; capsule | Generic drugs (ANDA) | January 31, 2019 |
| Bryant Ranch Prepack | 15 | tablet; capsule | Generic drugs (ANDA) | May 1, 2024 |
| Azurity Pharmaceuticals, Inc. | 14 | tablet; solution | Generic drugs (ANDA) | March 20, 2026 |
| Sandoz Inc | 14 | capsule, extended release; tablet | New drug applications (NDA) | May 31, 2005 |
| Golden State Medical Supply, Inc. | 13 | tablet, extended release; capsule, extended release | Generic drugs (ANDA) | November 26, 2021 |
| Haleon US Holdings LLC | 13 | tablet, film coated; tablet, coated | Over the counter monograph drugs | January 1, 2024 |
| KVK-Tech, Inc. | 13 | tablet; solution | Generic drugs (ANDA) | September 26, 2018 |
| Lupin Pharmaceuticals,Inc. | 13 | tablet; tablet, chewable | Generic drugs (ANDA) | April 25, 2016 |
| Solco Healthcare US, LLC | 13 | capsule; tablet | Generic drugs (ANDA) | December 5, 2023 |
| Takeda Pharmaceuticals America, Inc. | 13 | capsule; tablet, chewable | New drug applications (NDA) | January 28, 2017 |
| Alvogen Inc. | 12 | capsule; tablet | Generic drugs (ANDA) | August 25, 2023 |
| Medtech Products Inc. | 12 | powder | Over the counter monograph drugs | February 2, 2026 |
| NextWave Pharmaceuticals, Inc | 12 | suspension, extended release; tablet, extended release | New drug applications (NDA) | November 4, 2021 |
| NorthStar Rx LLC | 12 | tablet | Generic drugs (ANDA) | March 20, 2019 |
| Actavis Pharma, Inc. | 11 | capsule, extended release; capsule | Generic drugs (ANDA) | September 30, 2020 |
| Mylan Pharmaceuticals Inc. | 11 | capsule; patch | Generic drugs (ANDA) | August 25, 2023 |
| American Health Packaging | 10 | capsule; tablet, extended release | Generic drugs (ANDA) | December 24, 2025 |
| Dolgencorp, Inc. (dollar General & Rexall) | 10 | tablet, film coated; tablet | Over the counter monograph drugs | February 21, 2024 |
| Hikma Pharmaceuticals USA Inc. | 10 | capsule; tablet | Generic drugs (ANDA) | January 17, 2024 |
| Sunrise Pharmaceutical, Inc. | 10 | tablet; capsule | Generic drugs (ANDA) | July 4, 2018 |
| Takeda Pharmaceuticals America, Inc. | 10 | capsule, extended release | New drug applications (NDA) | June 20, 2017 |
| XLCare Pharmaceuticals, Inc. | 10 | tablet, extended release; tablet, chewable | Generic drugs (ANDA) | February 26, 2020 |
| Bayer HealthCare LLC. | 9 | tablet; powder | Over the counter monograph drugs | February 5, 2026 |
| Neos Therapeutics Brands, LLC | 9 | tablet, orally disintegrating | New drug applications (NDA) | June 20, 2017 |
| Neos Therapeutics, LP | 9 | tablet, orally disintegrating | Authorized generics (NDA) | July 1, 2026 |
| Teva Pharmaceuticals USA, Inc. | 9 | tablet | Generic drugs (ANDA) | March 19, 2003 |
| Ascend Laboratories, LLC | 8 | tablet; solution | Generic drugs (ANDA) | April 1, 2020 |
| Cardinal Health 110, LLC. DBA Leader | 8 | tablet, film coated; tablet | Over the counter monograph drugs | October 30, 2026 |
| Carolina Cannabis Creations LLC | 8 | chewable gel | Over the counter monograph drugs | November 14, 2025 |
| Cranbury Pharmaceuticals, LLC | 8 | tablet; solution | Generic drugs (ANDA) | August 20, 2022 |
| Dr. Reddy's Laboratories Inc. | 8 | capsule, extended release; tablet | Generic drugs (ANDA) | September 25, 2026 |
| Hahnemann Laboratories, Inc. | 8 | pellet | Unapproved homeopathic products | May 9, 2022 |
| Kroger Company | 8 | tablet; tablet, film coated | Over the counter monograph drugs | May 5, 2025 |
| Newton Laboratories, Inc. | 8 | liquid; pellet | Unapproved homeopathic products | September 25, 2023 |
| Novartis Pharmaceuticals Corporation | 8 | capsule, extended release | New drug applications (NDA) | May 31, 2005 |
| Noven Therapeutics, LLC | 8 | patch, extended release; patch | New drug applications (NDA) | May 15, 2023 |
| Par Health USA, LLC | 8 | capsule, extended release | Generic drugs (ANDA) | January 5, 2017 |
| Rite Aid Corporation | 8 | tablet, film coated; tablet | Over the counter monograph drugs | September 27, 2024 |
| Teva Pharmaceuticals USA, Inc. | 8 | capsule, extended release | Generic drugs (ANDA) | July 5, 2017 |
| Apotex Corp. | 7 | capsule | Generic drugs (ANDA) | November 9, 2023 |
| AvKARE | 7 | capsule | Generic drugs (ANDA) | June 4, 2025 |
| CVS Pharmacy | 7 | tablet; tablet, film coated | Over the counter monograph drugs | July 5, 2021 |
| Epic Pharma, LLC | 7 | tablet | Generic drugs (ANDA) | September 18, 2020 |
| Prasco Laboratories | 7 | capsule, extended release; solution | Authorized generics (NDA) | May 15, 2014 |
| Safeway | 7 | tablet; tablet, film coated | Over the counter monograph drugs | April 29, 2024 |
| Teva Pharmaceuticals USA, Inc. | 7 | tablet | Generic drugs (ANDA) | March 3, 2015 |
| Trigen Laboratories, LLC | 7 | tablet, extended release | Generic drugs (ANDA) | June 23, 2022 |
| Vertical Pharmaceuticals, LLC | 7 | tablet, extended release | New drug applications (NDA) | June 23, 2022 |
| Wilshire Pharmaceuticals, Inc. | 7 | tablet | Generic drugs (ANDA) | August 6, 2021 |
| Winder Laboratories LLC | 7 | tablet | Generic drugs (ANDA) | December 6, 2021 |
| Actavis Pharma, Inc. | 6 | capsule, extended release | Generic drugs (ANDA) | June 22, 2012 |
| Amneal Pharmaceuticals LLC | 6 | capsule | Generic drugs (ANDA) | August 28, 2023 |
| Ani Pharmaceuticals, Inc. | 6 | capsule, extended release | Generic drugs (ANDA) | March 16, 2020 |
| Aytu BioPharma, Inc. | 6 | capsule, extended release | New drug applications (NDA) | February 22, 2024 |
| Burel Pharmaceuticals, LLC | 6 | capsule, extended release | Generic drugs (ANDA) | December 16, 2019 |
| Novadoz Pharmaceuticals LLC | 6 | tablet, chewable | Generic drugs (ANDA) | February 2, 2024 |
| Oryza Pharmaceuticals Inc. | 6 | tablet | Generic drugs (ANDA) | October 19, 2020 |
| Target Corporation | 6 | tablet, film coated; tablet | Over the counter monograph drugs | April 7, 2025 |
| United Natural Foods, Inc. DBA Unfi | 6 | tablet, film coated; tablet | Over the counter monograph drugs | September 3, 2024 |
| Walmart Inc. | 6 | tablet, film coated; tablet | Over the counter monograph drugs | August 19, 2024 |
| Allegiant Health | 5 | tablet, film coated; capsule | Over the counter monograph drugs | November 5, 2024 |
| Amazon.com Services LLC | 5 | tablet, film coated | Generic drugs (ANDA) | September 11, 2026 |
| CVS Pharmacy | 5 | tablet, film coated | Over the counter monograph drugs | March 13, 2008 |
| Family Dollar (family Wellness) | 5 | tablet; tablet, film coated | Over the counter monograph drugs | January 25, 2024 |
| Glenmark Pharmaceuticals Inc., USA | 5 | tablet | Generic drugs (ANDA) | May 12, 2025 |
| Ironshore Pharmaceuticals Inc. | 5 | capsule | New drug applications (NDA) | June 1, 2019 |
| Kobayashi Healthcare International, Inc. | 5 | tablet, film coated; tablet, coated | Over the counter monograph drugs | October 31, 2024 |
| Navajo Manufacturing Company Inc. | 5 | tablet, film coated; tablet | Over the counter monograph drugs | March 13, 2025 |
| Nivagen Pharmaceuticals, Inc. | 5 | tablet | Generic drugs (ANDA) | May 3, 2024 |
| Quagen Pharmaceuticals LLC | 5 | capsule; solution | Generic drugs (ANDA) | May 1, 2024 |
| Actavis Pharma, Inc. | 4 | tablet, film coated, extended release | Generic drugs (ANDA) | March 4, 2019 |
| Advanced Rx of Tennessee, LLC | 4 | capsule; tablet | Generic drugs (ANDA) | January 8, 2026 |
| Chain Drug Marketing Association | 4 | tablet, film coated; powder | Over the counter monograph drugs | March 25, 2021 |
| Chain Drug Marketing Association, Inc. | 4 | tablet, film coated; tablet | Over the counter monograph drugs | September 2, 2025 |
| Guangzhou Ariel Biotech Co., Ltd. | 4 | liquid | Other unapproved drugs | April 2, 2026 |
| Janssen Pharmaceuticals, Inc. | 4 | tablet, extended release | New drug applications (NDA) | August 1, 2000 |
| L.N.K. International, Inc. | 4 | tablet, film coated; tablet | Over the counter monograph drugs | July 19, 2023 |
| LGM Pharma Solutions, LLC | 4 | capsule; tablet | Generic drugs (ANDA) | October 18, 2021 |
| Lannett Company, Inc. | 4 | tablet, extended release | Generic drugs (ANDA) | September 23, 2013 |
| Padagis US LLC | 4 | patch | Authorized generics (NDA) | June 5, 2023 |
| Pioneer Life Sciences, LLC | 4 | tablet | Over the counter monograph drugs | October 2, 2024 |
| Sandoz Inc | 4 | tablet | Generic drugs (ANDA) | June 14, 2002 |
| Time Cap Laboratories, Inc | 4 | tablet, film coated; tablet | Over the counter monograph drugs | June 16, 2021 |
| Topco Associates LLC | 4 | tablet, film coated | Over the counter monograph drugs | June 16, 2022 |
| Unifirst First Aid Corporation | 4 | tablet, film coated | Over the counter monograph drugs | September 26, 2022 |
Dosage forms
| Dosage form | Products | Share |
|---|---|---|
| Tablet | 445 | 32% |
| Capsule, extended release | 265 | 19.1% |
| Capsule | 190 | 13.7% |
| Tablet, film coated | 165 | 11.9% |
| Tablet, extended release | 59 | 4.2% |
| Tablet, chewable | 56 | 4% |
| Solution | 41 | 2.9% |
| Tablet, coated | 30 | 2.2% |
| Tablet, orally disintegrating | 24 | 1.7% |
| Powder | 23 | 1.7% |
| Liquid | 19 | 1.4% |
| Patch | 12 | 0.9% |
Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.