Data / New clinical trials / Substance-Related Disorders
Substance-Related Disorders trials: 288 new since Nov 2024
The full list. New Substance-Related Disorders clinical trials: 288 rows for $14.40, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 12 rows a month. The new rows come each week by email, $19 a month.
Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.
For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/substance-related-disorders, and every list with its row count and price is at https://specstream.ai/data/lists.json.
Updated November 9, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).
288 clinical studies in Substance-Related Disorders were first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026; 19 have an industry sponsor and 203 are recruiting or about to. The newest, NCT07926750, was posted on November 9, 2026: Community Context and Psychological Flexibility in Residential Substance Use Treatment: A Longitudinal... (Under The Tree Therapeutic Community).
The request: Every new Substance-Related Disorders clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.
SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.
- 288New trials
- 19Industry sponsored
- 203Recruiting or not yet
- November 9, 2026Latest posted
Newest trials
The newest 100 of 288, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.
| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
|---|---|---|---|---|---|---|---|---|---|
| November 9, 2026 | NCT07926750 | Community Context and Psychological Flexibility in Residential Substance Use Treatment: A Longitudinal Sequential Mediation Study | Under The Tree Therapeutic Community | Observational | Active not recruiting | Substance-Related Disorders, Substance Use Disorders | 80 | Mexico | clinicaltrials.gov |
| November 5, 2026 | NCT07918963 | Pilot of a Drug Education Curriculum for Middle and High School Students | Massachusetts General Hospital | Not applicable | Completed | Substance Use (Drugs, Alcohol), Health Risk Behaviors, Youth, Adolescent Behavior | 48 | United States | clinicaltrials.gov |
| November 4, 2026 | NCT07915882 | Rehabilitation Program for People With Methamphetamine-Associated Cardiopulmonary Conditions | Michael Incze | Not applicable | Recruiting | Methamphetamine-Associated Heart Failure, Methamphetamine-Associated Pulmonary Arterial Hypertension | 45 | United States | clinicaltrials.gov |
| November 2, 2026 | NCT07911332 | Justice Core Trial | University of North Carolina, Chapel Hill | Not applicable | Not yet recruiting | Pregnancy, Substance Use Disorder (SUD), Prisoners | 300 | United States | clinicaltrials.gov |
| November 2, 2026 | NCT07909447 | Effects of Qigong Exercise on Anxiety and Depression in Patients Receiving Inpatient Treatment for Substance Use Disorder | Uskudar University | Not applicable | Completed | Substance Use Disorder (SUD), Anxiety, Depression | 70 | Turkey (Türkiye) | clinicaltrials.gov |
| October 29, 2026 | NCT07903753 | RISE for PTSD and Substance Use Disorder in Veterans | VA Office of Research and Development | Not applicable | Not yet recruiting | Stress Disorders, Post-Traumatic, Substance-Related Disorders | 30 | United States | clinicaltrials.gov |
| October 21, 2026 | NCT07886944 | PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial) | Chestnut Health Systems | Not applicable | Enrolling by invitation | Burnout, Secondary Trauma, Compassion Fatigue, Opioid Use Disorder, Stimulant Use Disorder, Substance Use Disorder | 200 | United States | clinicaltrials.gov |
| October 20, 2026 | NCT07884422 | Cognitive Behavioral Therapy for Substance Use and Mental Health in University Students | Mehmet Akif Ersoy University | Not applicable | Completed | Substance Use Behavior | 90 | Turkey (Türkiye) | clinicaltrials.gov |
| October 15, 2026 | NCT07875361 | Disease Intervention Specialist (DIS) for SUD | Ohio State University | Observational | Not yet recruiting | Substance Use Disorder (SUD), Opioid Use Disorder, Alcohol Use Disorder (AUD), Drug Use, Overdose | 1,200 | United States | clinicaltrials.gov |
| October 14, 2026 | NCT07873944 | Recovery Management Checkup Scalability and Sustainability Hybrid Experiment | Chestnut Health Systems | Phase 3 | Not yet recruiting | Substance Use Disorder (SUD), Opioid Use Disorders, Stimulant Overdose, Overdose Risk, Alcohol Use Disorder | 600 | United States | clinicaltrials.gov |
| October 13, 2026 | NCT07871877 | Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder | Clive Michelsen | Phase 1/2 | Not yet recruiting | Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders | 60 | United States | clinicaltrials.gov |
| October 8, 2026 | NCT07865728 | Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents | Universidad Pública de Navarra | Not applicable | Not yet recruiting | Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety, Depression | 250 | clinicaltrials.gov | |
| October 8, 2026 | NCT07865234 | STI Screening for Women With Disabilities in Zambia | Centre for Infectious Disease Research in Zambia | Observational | Completed | Sexually Transmitted Infections, Women With Disabilities, Mental Health Conditions | 150 | Zambia | clinicaltrials.gov |
| October 5, 2026 | NCT07858513 | Evaluation of Effectiveness of the LifeSkills Training - Lombardia - Primary Shool Program ( Val3P-LST ) | Agenzia di Tutela della Salute della Città Metropolitana di Milano | Not applicable | Active not recruiting | Well Being, Drug Addiction, Tobacco Use, Alcohol Abuse, Life Skills, Violence, Bullying, Health Literacy | 3,927 | Italy | clinicaltrials.gov |
| October 1, 2026 | NCT07853092 | Brave Heart Intervention and Mental Health Outcomes Among Young People in Sierra Leone | Slum and Rural Health Initiative | Not applicable | Completed | Substance-related Disorders, Mental Health Literacy, Adolescent Health, Substance Use Disorder (SUD) | 2,244 | Sierra Leone | clinicaltrials.gov |
| October 1, 2026 | NCT07852052 | Sleep Architecture, Cognitive Function, and Quality of Life During Early Recovery From Substance Use Disorder | Assiut University | Observational | Not yet recruiting | Substance-Related Disorders, Substance Use Disorder, Sleep Wake Disorders, Cognitive Dysfunction | 34 | clinicaltrials.gov | |
| September 30, 2026 | NCT07849530 | Transcranial Magnetic Stimulation for Methamphetamine Use Disorder During Pregnancy | University of Utah | Not applicable | Not yet recruiting | Methamphetamine Use Disorder, Pregnancy | 45 | clinicaltrials.gov | |
| September 29, 2026 | NCT07846735 | Youth Overdose & Use Reduction in Rural Systems | Seattle Children's Hospital | Not applicable | Not yet recruiting | Substance Abuse, Opioid Abuse (Disorder), Overdose Prevention, Substance Use Disorder (SUD), Adolescent Substance Use... | 550 | clinicaltrials.gov | |
| September 28, 2026 | NCT07843576 | The ICEC Cluster Trial: Integrated Community Engagement Collaborative for Youth Substance Use Prevention in Rural America | West Virginia University | Not applicable | Not yet recruiting | Substance Use (Drugs, Alcohol), Tobacco Use, Adolescent Substance Use | 25,000 | United States | clinicaltrials.gov |
| September 24, 2026 | NCT07838311 | Delayed-Release, Extended-Release Methylphenidate (Jornay PM) for Adolescents and Young Adults With Attention-Deficit/Hyperactivity... | Massachusetts General Hospital | Phase 4 | Not yet recruiting | ADHD, Cannabis Use Disorder | 66 | United States | clinicaltrials.gov |
| September 21, 2026 | NCT07829510 | Transforming Trauma Care | Medical University of South Carolina | Not applicable | Not yet recruiting | Post-Traumatic Stress Disorder (PTSD), Depression, Substance Use Disorder, Traumatic Injury | 300 | clinicaltrials.gov | |
| September 17, 2026 | NCT07825857 | Randomized Controlled Trial of Tirzepatide for Methamphetamine Use Disorder | University of Texas Southwestern Medical Center | Phase 2 | Recruiting | Methamphetamine Use Disorder | 228 | United States | clinicaltrials.gov |
| September 15, 2026 | NCT07819851 | A Study of the Correlation Between the Severity of Substance Use Disorder and the Intensity of Dependence on Generative Artificial... | Centre Hospitalier Universitaire de Nice | Not applicable | Not yet recruiting | Substance-related Disorders, Behavior, Addictive, Artificial Intelligence (AI) | 100 | France | clinicaltrials.gov |
| September 11, 2026 | NCT07815691 | Endocannabinoids in Reward | Medical University of South Carolina | Phase 2 | Recruiting | Cannabis Use Disorder | 78 | United States | clinicaltrials.gov |
| September 11, 2026 | NCT07814755 | Auricular Vagal Neuromodulation for Depression and Anxiety in Substance Use Disorder | Daisy Thompson-Lake | Not applicable | Not yet recruiting | Substance Use Disorder (SUD) | 50 | United States | clinicaltrials.gov |
| September 10, 2026 | NCT07812987 | Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health | Tactical Mind Research Coalition, Inc. | Not applicable | Active not recruiting | Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance | 240 | United States | clinicaltrials.gov |
| September 10, 2026 | NCT07812831 | Clinical Time and Temporal Dynamics Study (CLIN-TIME) | Truway Health, Inc. | Observational | Enrolling by invitation | Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests, Telemedicine, Time of Death, Time... | 1,000 | United States | clinicaltrials.gov |
| September 9, 2026 | NCT07809854 | Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment | VA Office of Research and Development | Phase 4 | Not yet recruiting | Cigarette Smoking, Veterans | 112 | United States | clinicaltrials.gov |
| September 4, 2026 | NCT07804121 | Project SHIELD 2.0: Police Education to Support Public Health in Kentucky | Johns Hopkins Bloomberg School of Public Health | Not applicable | Recruiting | HIV, Substance Use Disorder (SUD) | 150 | United States | clinicaltrials.gov |
| August 24, 2026 | NCT07782268 | Written Exposure in Substance Treatment (WEST 3.0): Randomized Controlled Trial | Potomac Health Foundations | Not applicable | Not yet recruiting | Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD) | 400 | United States | clinicaltrials.gov |
| August 20, 2026 | NCT07776457 | Substance Use in Pregnancy - Optimizing Retention in Treatment by Maximizing Opportunities for Management | Washington University School of Medicine | Phase 2 | Not yet recruiting | Pregnancy, Substance Use Disorder (SUD) | 245 | United States | clinicaltrials.gov |
| August 20, 2026 | NCT07775807 | Closed-loop TBS Targeting rPO for the Core Clinical Features of Methamphetamine Use Disorder | Shanghai Mental Health Center | Not applicable | Active not recruiting | Methamphetamine Use Disorder, Substance Use Disorder, Cue-reactivity, Craving | 5 | China | clinicaltrials.gov |
| August 19, 2026 | NCT07774702 | Psilocybin for Methamphetamine Use Disorder | Peter Hendricks | Phase 2 | Not yet recruiting | Methamphetamine Use Disorder | 42 | United States | clinicaltrials.gov |
| August 17, 2026 | NCT07768007 | Real-time Opioid Study | Yale University | Not applicable | Recruiting | Substance Use Disorder (SUD) | 3 | United States | clinicaltrials.gov |
| August 11, 2026 | NCT07756723 | The Many Roads to Trauma Recovery: A Clinical Trial Comparing Empirically Supported Treatments for Veterans With Co-Morbid Posttraumatic... | Coatesville VA Medical Center | Phase 2/3 | Recruiting | Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD) | 50 | United States | clinicaltrials.gov |
| August 5, 2026 | NCT07746401 | Recovery Opportunities Through Ongoing Treatment Sustainment | University of Maryland, College Park | Not applicable | Not yet recruiting | Substance Use Disorders (SUDs) | 60 | clinicaltrials.gov | |
| August 4, 2026 | NCT07744841 | Supportive Treatment With Enhanced Post-Incarceration Services | Catherine E. Paquette, PhD | Not applicable | Not yet recruiting | Substance Use Disorders (SUDs) | 120 | clinicaltrials.gov | |
| August 3, 2026 | NCT07743359 | Enhancing Delivery of Parenting Support Within a Peer Recovery Support Service Model | Baystate Medical Center | Not applicable | Not yet recruiting | Substance Use Disorders (SUDs) | 288 | United States | clinicaltrials.gov |
| August 3, 2026 | NCT07742722 | Honest, Open, Proud (HOP): A Peer Delivered, Co-occurring Disorders Intervention for Justice-involved Veterans | VA Office of Research and Development | Not applicable | Recruiting | Stigma, Co-Occurring Disorders, Substance Use Disorder, Mental Health Disorder, Veterans | 240 | United States | clinicaltrials.gov |
| August 3, 2026 | NCT07741825 | Mindfulness-based Relapse Prevention for Peer Workers | University of Texas at Austin | Not applicable | Recruiting | Relapse/Recurrence, Substance Use (Drugs, Alcohol), Burnout | 80 | United States | clinicaltrials.gov |
| July 31, 2026 | NCT07740395 | Connecting Loved Ones to Support and Empowering Recovery | Rhode Island Hospital | Not applicable | Recruiting | Substance Use Disorder (SUD), mHealth | 60 | United States | clinicaltrials.gov |
| July 30, 2026 | NCT07737652 | Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders | University of Alabama, Tuscaloosa | Not applicable | Completed | Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder | 61 | United States | clinicaltrials.gov |
| July 30, 2026 | NCT07735481 | Promoting Recovery by Overcoming Self-stigma in Mental Health Disorders With a Narrative Enhancement and Cognitive Therapy (NECT) Group... | Louise Penzenstadler | Not applicable | Not yet recruiting | Mental Disorders, Substance Use Disorders | 106 | Switzerland | clinicaltrials.gov |
| July 29, 2026 | NCT07734701 | Pregnenolone Treatment for Alcohol Use Disorder and Major Depressive Disorder | Sherwood Brown, MD, PhD | Phase 2 | Not yet recruiting | Alcohol Use Disorder (AUD), Major Depressive Disorder (MDD) | 100 | United States | clinicaltrials.gov |
| July 29, 2026 | NCT07734363 | Role of Craving in the Transition Across Level of Addiction Severity: A Longitudinal Study. | University of Bordeaux | Observational | Recruiting | Addiction | 700 | France | clinicaltrials.gov |
| July 28, 2026 | NCT07731295 | iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery | Brown University | Not applicable | Recruiting | Pain, Postoperative, Substance Use | 150 | United States | clinicaltrials.gov |
| July 24, 2026 | NCT07725289 | Clinician Practice Companion to Address Youth Substance Use | Massachusetts General Hospital | Not applicable | Not yet recruiting | Substance Use, Substance-Related Disorders, Adolescent Substance Use, Cannabis Use, Opioid Use Disorder, Drug Overdose... | 60 | Canada, United States | clinicaltrials.gov |
| July 23, 2026 | NCT07721896 | University Survey on Consumer Behavior and Mental Health | University Hospital, Strasbourg, France | Observational | Not yet recruiting | Consumer Behavior, Mental Health, Consumption, Stress and Anxiety | 245 | France | clinicaltrials.gov |
| July 21, 2026 | NCT07716202 | Homeless Overdose Prevention- Expansion | VA Office of Research and Development | Not applicable | Not yet recruiting | Homelessness, Opioid Education and Naloxone Distribution (OEND), Substance Use Disorder | 1,200 | United States | clinicaltrials.gov |
| July 16, 2026 | NCT07707115 | Interprofessional Simulation Program for Clinical Resilience and Empathy: Project INSPIRE | University of Utah | Not applicable | Recruiting | Substance Use Disorders, Simulation Training, Pregnancy Related, Patient-centered Care, Bias, Implicit | 300 | United States | clinicaltrials.gov |
| July 15, 2026 | NCT07705113 | Effectiveness of Depression and Substance Use Module for Patients With Co-occurring Disorders | International Islamic University, Islamabad | Not applicable | Active not recruiting | Depression, Substance Use Disorders | 50 | Pakistan | clinicaltrials.gov |
| July 14, 2026 | NCT07702110 | Anabolic-Androgenic Steroid Use Among Gym-Goers | Alaa Yousif Ayed Ahmed | Not applicable | Not yet recruiting | Anabolic Androgenic Steroid Use, Substance-Related Disorders | 120 | Iraq | clinicaltrials.gov |
| July 14, 2026 | NCT07700407 | Preventing Overdose and Promoting Recovery Through Court Navigation | RTI International | Not applicable | Not yet recruiting | Substance Use Disorder (SUD) | 600 | United States | clinicaltrials.gov |
| July 13, 2026 | NCT07699484 | Digital Intervention Delivered Via Street Medicine to Increase HIV and Substance Use Care Among Survivors of Sex Trafficking | Lifespan | Early phase 1 | Not yet recruiting | Sex Trafficking, HIV, Substance Use (Drugs, Alcohol), Mental Health, Sexual Violence, Treatment Engagement | 60 | United States | clinicaltrials.gov |
| July 13, 2026 | NCT07698821 | Emotion Regulation Program for Substance Use Disorders | The Catholic University of Korea | Not applicable | Not yet recruiting | Substance Use Disorder (SUD) | 20 | South Korea | clinicaltrials.gov |
| July 13, 2026 | NCT07698808 | Craving Management Program for Substance Use Disorders | The Catholic University of Korea | Not applicable | Not yet recruiting | Substance Use Disorder (SUD) | 20 | South Korea | clinicaltrials.gov |
| July 10, 2026 | NCT07695818 | Testing and Evaluation of the Returning to the Land Intervention to Address and Prevent Substance Misuse | Johns Hopkins Bloomberg School of Public Health | Not applicable | Recruiting | Substance Use, Children, Cultural Factors | 60 | United States | clinicaltrials.gov |
| July 9, 2026 | NCT07693439 | Implementing DBT in Short-Term SUD-treatment | Helse Møre og Romsdal HF | Not applicable | Enrolling by invitation | Substance Abuse Disorder, Dialectical Behavior Therapy, Emotion Management Skills | 82 | Norway | clinicaltrials.gov |
| July 9, 2026 | NCT07692984 | The Effect of Comorbid Alcohol/Substance Use | Abant Izzet Baysal University | Observational | Recruiting | Alcohol Abuse, Alcohol Use Disorder, Substance Use Disorders, Severe Mental Disorder, Schizophrenia, Bipolar Disorder... | 297 | Turkey (Türkiye) | clinicaltrials.gov |
| July 8, 2026 | NCT07689981 | The Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation in Individuals With Tiletamine Use Disorder | Shanghai Mental Health Center | Not applicable | Not yet recruiting | Tiletamine Use Disorder, Substance Use Disorder (SUD), Drug Craving | 30 | China | clinicaltrials.gov |
| July 6, 2026 | NCT07684976 | Safety and Feasibility of Next-Generation Dome Helmet (NGDH) for Focused Ultrasound Neuromodulation in Substance Use Disorder (SUD) | Sunnybrook Health Sciences Centre | Not applicable | Recruiting | Substance Use Disorder (SUD) | 20 | Canada | clinicaltrials.gov |
| July 2, 2026 | NCT07682441 | CBITS-RTM Pilot Study | University of California, San Francisco | Not applicable | Not yet recruiting | PTSD - Post Traumatic Stress Disorder, Substance Use | 28 | United States | clinicaltrials.gov |
| June 29, 2026 | NCT07672457 | Substance Use Prevention for Recently Displaced Adults - SUPRA (R33) RCT | Boston Medical Center | Not applicable | Not yet recruiting | Prevention, Substance Use, Refugee Health | 144 | Ukraine | clinicaltrials.gov |
| June 24, 2026 | NCT07665502 | Pre-Pilot (R61) WINGS+++: mHealth to Improve MOUD Uptake in Women Experiencing Intimate Partner Violence and PTSD | Dawn A. Goddard-Eckrich | Not applicable | Enrolling by invitation | Opioid-Related Disorders, Substance-Related Disorders, Intimate Partner Violence (IPV), Stress Disorders... | 7 | United States | clinicaltrials.gov |
| June 22, 2026 | NCT07658963 | First Step Program for Substance Use Disorders | The Catholic University of Korea | Not applicable | Not yet recruiting | Substance Use Disorder (SUD) | 20 | South Korea | clinicaltrials.gov |
| June 18, 2026 | NCT07655609 | LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High School | Prevention Strategies, LLC | Not applicable | Not yet recruiting | Substance-related Disorders, Alcohol-Related Disorders, Tobacco Use Disorder, Marijuana Use | 5,000 | clinicaltrials.gov | |
| June 17, 2026 | NCT07652645 | Hybrid Dialectical Behavior Therapy for Veterans to Further Reduce Emotion Regulation Problems and Trauma Symptoms | Arkin | Not applicable | Recruiting | PTSD, Emotion Regulation Disorders, Substance Abuse | 24 | Netherlands | clinicaltrials.gov |
| June 16, 2026 | NCT07649278 | The ENHANCE Project Toolkit | University of Wisconsin, Madison | Not applicable | Recruiting | Substance Related Disorder, Drug Overdose, eHealth | 40 | United States | clinicaltrials.gov |
| June 12, 2026 | NCT07645131 | Development of a Mobile Health Intervention to Support Functioning of Veterans With Substance Use Disorders | VA Office of Research and Development | Not applicable | Not yet recruiting | Substance Use | 30 | United States | clinicaltrials.gov |
| June 11, 2026 | NCT07641712 | General Well-being After Quitting Drug Use | Alanya Alaaddin Keykubat University | Observational | Not yet recruiting | Drug Abuse | 120 | clinicaltrials.gov | |
| June 11, 2026 | NCT07640672 | The WARM Study is a Pilot Study That Aims to Investigate the Impact of Environmental Factors on Acute and Chronic Wounds, Mental Illness... | University Hospital Augsburg | Not applicable | Not yet recruiting | Homeless Persons, Wound and Injuries, Chronic Wound Care, Homelessness, Environmental Health, Environmental Factors... | 100 | Germany | clinicaltrials.gov |
| June 10, 2026 | NCT07637669 | Olfactory Function and Model-Based Behavior in People Living With HIV and SUD | National Institute on Drug Abuse (NIDA) | Observational | Recruiting | HIV, Substance Use Disorder | 120 | United States | clinicaltrials.gov |
| June 8, 2026 | NCT07631559 | Pilot Study of an Adapted Partner Navigation Intervention Booster Session for Sustained Healthcare Engagement Among People Who Inject Drugs | University of California, San Francisco | Not applicable | Not yet recruiting | HEPATITIS C (HCV), Opioid Use Disorder, Substance Use Disorder (SUD), Drug Use Disorders, Healthcare Access, Harm... | 50 | United States | clinicaltrials.gov |
| June 2, 2026 | NCT07621731 | Pathway-Matched Resilience-Oriented Therapy in Rwanda | Alexandros Lordos, PhD | Not applicable | Completed | Mental Health, Psychological Trauma, Stress Disorders, Post-Traumatic, Depression, Anxiety, Aggression... | 427 | Rwanda | clinicaltrials.gov |
| May 22, 2026 | NCT07602699 | Multi-Site Trial of Tirzepatide for Smoking Cessation | University of Southern California | Phase 2 | Recruiting | Smoking Cessation, Smoking Behaviors | 300 | United States | clinicaltrials.gov |
| May 20, 2026 | NCT07599722 | mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System | University of Pittsburgh | Not applicable | Not yet recruiting | HIV Prevention, Substance Use | 50 | United States | clinicaltrials.gov |
| May 19, 2026 | NCT07597863 | A Study to Investigate Health Related Quality of Life With a Pharmacist Intervention Compared to Treatment as Usual in Participants With... | Sykehuset Innlandet HF | Not applicable | Not yet recruiting | Severe Mental Illness, Substance Use Disorder (SUD) | 160 | Norway | clinicaltrials.gov |
| May 19, 2026 | NCT07597447 | The Impact of Trauma-Informed Sports-Based Intervention on Emotion Regulation, Self-Esteem, and Peer Relationships in Adolescents With... | Neslihan Lok | Not applicable | Completed | Adolescents With Substance Use Disorder | 120 | Turkey (Türkiye) | clinicaltrials.gov |
| May 19, 2026 | NCT07595614 | NLP Analysis of Weekly Narratives for Dynamic Clinical Assessment in SUD | Lauro Gutiérrez Castro | Observational | Recruiting | Substance Use Disorder (SUD), Addiction, Anxiety, Emotional Dysregulation, Rumination - Thoughts | 35 | Mexico | clinicaltrials.gov |
| May 19, 2026 | NCT07594730 | Brief Intervention Addressing Stigma Among Parents of Children With Mental Health Problems | New York State Psychiatric Institute | Not applicable | Not yet recruiting | Depression Disorders, ADHD, Substance Abuse, Social Stigma, Help-Seeking Behavior, Caregiver Burden | 1,600 | United States | clinicaltrials.gov |
| May 18, 2026 | NCT07593274 | Continuing Care for Justice-involved Individuals | Friends Research Institute, Inc. | Not applicable | Completed | Substance Use Disorder (SUD) | 31 | United States | clinicaltrials.gov |
| May 18, 2026 | NCT07592195 | A Study on the Effects of Breathing Exercises and Aerobic Exercise on the Health of Men in Drug Rehabilitation | Southwest Medical University | Not applicable | Recruiting | Disorders, Substance Related | 90 | China | clinicaltrials.gov |
| May 15, 2026 | NCT07590154 | Cross-sectional Functional Stratification Based on Psychometric Profiling and Machine Learning in Patients With Substance Use Disorders... | Lauro Gutiérrez Castro | Observational | Completed | Substance Abuse Disorder, Addiction, Clinical Stratification, Substance-related Disorders, Residential Treatment Program | 155 | Mexico | clinicaltrials.gov |
| May 15, 2026 | NCT07590115 | Behavioral Rigidity in Residential Treatment for Substance Use Disorder (RIG-TD) | Lauro Gutiérrez Castro | Observational | Enrolling by invitation | Substance Use Disorder (SUD), Anxiety, Depression Anxiety Disorder | 35 | Mexico | clinicaltrials.gov |
| May 14, 2026 | NCT07588516 | Dynamic Multilevel Processes of Recovery in Therapeutic Communities in Mexico (DICO Model) | Under The Tree Therapeutic Community | Observational | Not yet recruiting | Substance Use Disorder (SUD), Treatment Adherence | 60 | Mexico | clinicaltrials.gov |
| May 14, 2026 | NCT07585656 | Comparison of the Italian and U.S. Forensic Models for Dual-diagnosis Offenders: a 3-year Longitudinal Study | University of Bari | Observational | Not yet recruiting | SCHIZOPHRENIA 1 (Disorder), Substance Abuse | 600 | clinicaltrials.gov | |
| May 12, 2026 | NCT07581353 | Effect Of Psychoeducation On Substance Craving Levels And Psychological Resilience | University of Gaziantep | Not applicable | Completed | Psychoeducation Study | 60 | Turkey (Türkiye) | clinicaltrials.gov |
| May 12, 2026 | NCT07579299 | Engaging Family Members During Early SUD Treatment: A Hybrid Trial | Stanford University | Not applicable | Not yet recruiting | Substance Use Disorder (SUD) | 100 | United States | clinicaltrials.gov |
| May 8, 2026 | NCT07575373 | Feasibility of an Interdisciplinary Intervention to Improve Care Transitions for Hospitalized Patients With Substance Use Disorders | Michael Incze | Not applicable | Recruiting | Substance Use Disorders | 75 | United States | clinicaltrials.gov |
| May 5, 2026 | NCT07566273 | Micropractices for Unhoused LGBTQ Youth | Cornell University | Early phase 1 | Not yet recruiting | Well-Being (Psychological Flourishing), Internalizing Mental Health Symptoms, Substance Abuse | 200 | United States | clinicaltrials.gov |
| May 4, 2026 | NCT07563517 | Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches & Across INcarceration Settings | Emory University | Not applicable | Recruiting | Substance Use | 550 | United States | clinicaltrials.gov |
| April 29, 2026 | NCT07556861 | Senyo Health App - Comorbid Alcohol Use Disorder Treatment in Individuals With Bipolar Disorder Using a Telehealth Collaborative Care... | Mayo Clinic | Not applicable | Not yet recruiting | Bipolar Disorder | 40 | United States | clinicaltrials.gov |
| April 29, 2026 | NCT07555145 | Supporting Treatment Access and Recovery in Re-entry (STAR-R) | University of Massachusetts, Worcester | Not applicable | Recruiting | Mental Health, Substance Use Disorders, Co-occurring Mental and Substance Use Disorders | 240 | United States | clinicaltrials.gov |
| April 27, 2026 | NCT07552623 | Adapted RPM-08 for Substance Use Disorder in Pakistan | Universiti Sains Malaysia | Not applicable | Completed | Substance Use Disorder (SUD), Drug Abuse, Relapse | 70 | Pakistan | clinicaltrials.gov |
| April 14, 2026 | NCT07529327 | Prevent Language Delays and Disorders Among Children of Caregivers With Substance Use Disorders With Community Groups and Individualized... | University of Oregon | Not applicable | Recruiting | Language Delay, Substance Use Disorders, Language Disorders in Children, Language Development, Prevention Intervention | 244 | United States | clinicaltrials.gov |
| April 14, 2026 | NCT07528846 | Justice Community Overdose Innovation Network II TCU Hub | Texas Christian University | Not applicable | Not yet recruiting | Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior | 1,620 | United States | clinicaltrials.gov |
| April 14, 2026 | NCT07527871 | Emergency Department-Substance Use Screening, Motivational Interviewing and Active Referral Targeting Substance Use Disorder and Overdose... | Purdue University | Not applicable | Enrolling by invitation | Substance Use (Drugs, Alcohol) | 650 | United States | clinicaltrials.gov |
| April 9, 2026 | NCT07520617 | Evaluation of the ADD'Pro Vocational Reintegration Program (ADD-PRO-EVAL) | University Hospital, Clermont-Ferrand | Not applicable | Not yet recruiting | Addiction, Addiction Disorders, Substance Use Recovery, Return to Work, Recovery, Recovery Outcomes, Substance Use... | 100 | France | clinicaltrials.gov |
| April 9, 2026 | NCT07519759 | Recovery Inspired Support Engagement (RISE) Pilot | Mclean Hospital | Not applicable | Recruiting | Support Persons, Family Members, Chosen Family, Romantic Partners, Friends, Caregivers, Substance Use Disorders | 18 | United States | clinicaltrials.gov |
| April 7, 2026 | NCT07516301 | Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult... | St. Jude Children's Research Hospital | Not applicable | Recruiting | Survivors of Childhood Cancer, Substance Use | 30 | United States | clinicaltrials.gov |
Sponsors posting most
| Sponsor | New trials | Latest |
|---|---|---|
| VA Office of Research and Development | 7 | October 29, 2026 |
| Chestnut Health Systems | 5 | October 21, 2026 |
| Medical University of South Carolina | 5 | September 21, 2026 |
| Johns Hopkins Bloomberg School of Public Health | 5 | September 4, 2026 |
| Yale University | 5 | August 17, 2026 |
| University of California, San Francisco | 5 | July 2, 2026 |
| Lauro Gutiérrez Castro | 5 | May 19, 2026 |
| Massachusetts General Hospital | 4 | November 5, 2026 |
| Washington University School of Medicine | 4 | August 20, 2026 |
| Institute of HIV Research and Innovation Foundation, Thailand | 4 | April 6, 2026 |
| Ohio State University | 3 | October 15, 2026 |
| University of Utah | 3 | September 30, 2026 |
| Potomac Health Foundations | 3 | August 24, 2026 |
| Shanghai Mental Health Center | 3 | August 20, 2026 |
| Rhode Island Hospital | 3 | July 31, 2026 |
| The Catholic University of Korea | 3 | July 13, 2026 |
| National Institute on Drug Abuse (NIDA) | 3 | June 10, 2026 |
| University of Pittsburgh | 3 | May 20, 2026 |
| Mclean Hospital | 3 | April 9, 2026 |
| University of California, Los Angeles | 3 | April 3, 2026 |
By phase
| Phase | New trials | Latest |
|---|---|---|
| Not applicable | 213 | November 5, 2026 |
| Observational | 43 | November 9, 2026 |
| Phase 2 | 11 | September 17, 2026 |
| Early phase 1 | 7 | July 13, 2026 |
| Phase 4 | 5 | September 24, 2026 |
| Phase 1 | 4 | October 20, 2025 |
| Phase 3 | 2 | October 14, 2026 |
| Phase 1/2 | 2 | October 13, 2026 |
| Phase 2/3 | 1 | August 11, 2026 |
By country
| Country | New trials | Latest |
|---|---|---|
| United States | 167 | November 5, 2026 |
| Canada | 11 | July 24, 2026 |
| Turkey (Türkiye) | 10 | November 2, 2026 |
| France | 9 | September 15, 2026 |
| China | 8 | August 20, 2026 |
| Mexico | 7 | November 9, 2026 |
| Germany | 7 | June 11, 2026 |
| Pakistan | 6 | July 15, 2026 |
| Switzerland | 4 | July 30, 2026 |
| Norway | 4 | July 9, 2026 |
| Thailand | 4 | April 6, 2026 |
| Spain | 4 | March 2, 2026 |
| Italy | 3 | October 5, 2026 |
| South Korea | 3 | July 13, 2026 |
| Egypt | 3 | September 19, 2025 |
| Hong Kong | 2 | July 29, 2025 |
| Austria | 2 | June 19, 2025 |
| Zambia | 1 | October 8, 2026 |
| Sierra Leone | 1 | October 1, 2026 |
| Iraq | 1 | July 14, 2026 |
| Ukraine | 1 | June 29, 2026 |
| Netherlands | 1 | June 17, 2026 |
| Rwanda | 1 | June 2, 2026 |
| Australia | 1 | April 3, 2026 |
| Colombia | 1 | January 9, 2026 |
Where the register publishes
U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.