New Smoking clinical trials: 158 posted since Nov 2024

Name: New Smoking clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Smoking clinical trials: 158 rows for $7.90, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 8 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (sponsor class, condition groups (MeSH), interventions, start date, enrollment type, location countries and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/smoking, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 4, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

158 clinical studies in smoking were first posted on ClinicalTrials.gov from November 14, 2024 to November 4, 2026; 19 have an industry sponsor and 95 are recruiting or about to. The newest, NCT07915570, was posted on November 4, 2026: Salivary IL-8 and Serum IL-6 as Biomarkers for Oral Potentially Malignant Disorders in Smokers and... (British University In Egypt).

The request: Every new Smoking clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

158New trials
19Industry sponsored
95Recruiting or not yet
November 4, 2026Latest posted

Newest trials

The newest 100 of 158, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 4, 2026	NCT07915570	Salivary IL-8 and Serum IL-6 as Biomarkers for Oral Potentially Malignant Disorders in Smokers and Never-Smokers	British University In Egypt	Observational	Recruiting	Oral Potentially Malignant Disorders, Oral Lichen Planus, Oral Leukoplakia, Oral Squamous Cell Carcinoma, Smoking	250	Egypt	clinicaltrials.gov
November 2, 2026	NCT07910214	Effectiveness of Volitional Help Sheets as an Adjunct to Treatment to Promote Behavior Change: A Pilot Study on Smoking	Clinique de la Mitterie	Not applicable	Recruiting	Tobacco Dependence	376	France	clinicaltrials.gov
October 30, 2026	NCT07907601	Impact of Multidisciplinary Care, Structured and Targeted on the COPD Patient's Clinical Pathway.	Centre Hospitalier Universitaire de Nīmes	Not applicable	Not yet recruiting	Chronic Obstructive Pulmonary Disease, Lung Diseases, Obstructive, Lung Disease Chronic	116	France	clinicaltrials.gov
October 27, 2026	NCT07897162	Effect of Smoking on Salivary and Serum Metabolomic Profiles in Periodontitis	Ankara University	Observational	Completed	Periodontitis	48	Turkey (Türkiye)	clinicaltrials.gov
October 21, 2026	NCT07887217	THE EFFECT OF A TRANSTHEORETICAL MODEL-BASED CHATBOT SUPPORT INTERVENTION ON SMOKING BEHAVIOR IN UNIVERSITY STUDENTS	Seher DÖNER	Not applicable	Active not recruiting	Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation, Tobacco Smoking	100	Turkey (Türkiye)	clinicaltrials.gov
October 20, 2026	NCT07881848	A Study to Assess Nicotine Uptake From a Menthol Electronic Nicotine Delivery System Product	RAI Services Company	Not applicable	Not yet recruiting	Smoking Behaviors, Smoking ( Cigarette), Tobacco Use, Abuse Liability	28		clinicaltrials.gov
October 19, 2026	NCT07880717	Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years	Mahidol University	Observational	Recruiting	Diabete Mellitus, Dyslipidaemia, Chronic Kidney Disease, Psychiatric Disorder, Hypertension, Hypothyroidism, Smoking...	93	Thailand	clinicaltrials.gov
October 19, 2026	NCT07879638	A Study to Determine the Effect of Access to Multiple Tobacco Flavor Options on Smoking Abstinence Among Primary Cigarette Smokers Using an...	RAI Services Company	Not applicable	Recruiting	Smoking, Tobacco	480	United States	clinicaltrials.gov
October 13, 2026	NCT07871656	Lung Cancer Detection in Never Smokers Using Urine Volatile Organic Compound (VOCs)	Thomas Jefferson University	Observational	Recruiting	Lung Cancer	87	United States	clinicaltrials.gov
October 6, 2026	NCT07860359	Impact of Lung Cancer Screening With Chest Scans Combined With Coaching on Smoking Cessation in Heavy Smokers	Hôpital Fribourgeois	Not applicable	Not yet recruiting	Lung Cancer (Diagnosis), Smoking Cessation, Lung Neoplasm	116	Switzerland	clinicaltrials.gov
October 1, 2026	NCT07851584	Er,Cr:YSGG Laser in Smokers With Stage III Periodontitis	Okan University	Not applicable	Completed	Periodontitis (Stage 3)	20	Turkey (Türkiye)	clinicaltrials.gov
September 24, 2026	NCT07840118	Smartphone-based Incentives Intervention to Increase Smoking Cessation During Pregnancy	University of Vermont	Not applicable	Not yet recruiting	Smoking During Pregnancy and Postpartum, Perinatal Cigarette Smoking	137	United States	clinicaltrials.gov
September 18, 2026	NCT07828990	Cardiovascular Risk Factors and Lipid Profile in Hospitalized Mexican Adults	Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo	Observational	Completed	Dyslipidemia	107	Mexico	clinicaltrials.gov
September 17, 2026	NCT07826728	SMOKING AND GINGIVAL CREVICULAR FLUID MFN1 AND NLRP3 LEVELS IN PERIODONTAL HEALTH AND PERIODONTITIS	Abant Izzet Baysal University	Observational	Recruiting	Periodontitis, Smoking	88	Turkey (Türkiye)	clinicaltrials.gov
September 14, 2026	NCT07819318	C-Raven LDCT: Lung Cancer Screening Intervention	Johns Hopkins University	Not applicable	Not yet recruiting	Lung Cancer Screening	300		clinicaltrials.gov
August 31, 2026	NCT07794969	Pancreatic Cancer Lifestyle Evolution And Resistance	IRCCS San Raffaele	Observational	Not yet recruiting	Pancreatic Cancer	150		clinicaltrials.gov
August 27, 2026	NCT07789132	Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking	Massachusetts General Hospital	Not applicable	Not yet recruiting	Nicotine Dependance, Serious Mental Illness, Smoking (Tobacco) Addiction, Tobacco Cessation, Community Health Workers...	937	United States	clinicaltrials.gov
August 24, 2026	NCT07782879	DoubleTake: Effect of Message Exposure Via a Discrete Choice Experiment With Eye-Tracking on Quit Attempts Among Adults Who Smoke Menthol...	Georgia State University	Not applicable	Recruiting	Menthol Cigarettes, Smoking Behavior, Cigarette Use	200	United States	clinicaltrials.gov
August 18, 2026	NCT07770633	Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty	The Cleveland Clinic	Not applicable	Not yet recruiting	Wound Surgical, Diabetes, Obesity, Chronic Kidney Diseases, Smoking	300		clinicaltrials.gov
August 14, 2026	NCT07766655	Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)	Axsome Therapeutics, Inc.	Phase 3	Recruiting	Smoking Cessation	705	United States	clinicaltrials.gov
August 14, 2026	NCT07765251	Angiogenesis in Periodontal Disease	Inonu University	Observational	Completed	Gingivitis	114	Turkey (Türkiye)	clinicaltrials.gov
August 14, 2026	NCT07764549	Salivary TNF-α, FoxO-1, and SIRT-1 Levels in Periodontitis and Smoking	Zehra Hasgül	Observational	Completed	Periodontitis (Stage 3), Smoking ( Cigarette)	80	Turkey (Türkiye)	clinicaltrials.gov
August 11, 2026	NCT07758998	The Effect of Motivational Interviewing on Smoking Behavior Among Nursing Students	Meral Feratoğlu Research	Not applicable	Not yet recruiting	Tobacco Use, Smoking Cessation	87	Turkey (Türkiye)	clinicaltrials.gov
August 10, 2026	NCT07754578	DOSE-UP: Dose Optimization for Smoking and E-Cigarette Use Pharmacotherapy	Medical University of South Carolina	Phase 2	Not yet recruiting	Dual Use of Cigarettes and E-cigarettes	321	United States	clinicaltrials.gov
August 6, 2026	NCT07750171	Impact of Smoking on Immune Responses in Peri-implant Health and Disease	Gazi University	Observational	Recruiting	Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis	216	Turkey (Türkiye)	clinicaltrials.gov
August 5, 2026	NCT07746492	Just-in-Time Support for Smoking, Vaping, and Eating Urges During High-Stress Moments Among Gender and Sexual Minority Adults in Dhaka	International Centre for Diarrhoeal Disease Research, Bangladesh	Not applicable	Not yet recruiting	Tobacco Use, Electronic Cigarette Use, Emotional Eating, Stress, Psychological	115	Bangladesh	clinicaltrials.gov
July 31, 2026	NCT07739797	A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery System Products	RAI Services Company	Not applicable	Not yet recruiting	Smoking Behaviors, Smoking ( Cigarette), Tobacco Use	50		clinicaltrials.gov
July 30, 2026	NCT07737587	Yoga-Based Breathing Exercises in a Salt-Cave Environment Versus a Standard Clinical Setting in Smokers	Sinop University	Not applicable	Completed	Tobacco Smoking, Respiratory Function	60	Turkey (Türkiye)	clinicaltrials.gov
July 20, 2026	NCT07714200	Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness	VA Office of Research and Development	Not applicable	Not yet recruiting	Tobacco Use Disorder	120	United States	clinicaltrials.gov
July 17, 2026	NCT07711691	Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)	University of California, Irvine	Not applicable	Recruiting	Lung Cancer Screening, Lung Neoplasms, Smoking ( Cigarette), Early Detection of Cancer	80	United States	clinicaltrials.gov
July 17, 2026	NCT07710820	A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette...	RAI Services Company	Not applicable	Recruiting	Smoking, Tobacco	1,060	United States	clinicaltrials.gov
July 13, 2026	NCT07698470	Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use	University of Southern California	Not applicable	Recruiting	Nicotine Dependence	45	United States	clinicaltrials.gov
July 6, 2026	NCT07685795	Abuse Liability of Four Modern Oral Nicotine Products	RAI Services Company	Not applicable	Not yet recruiting	Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking	50		clinicaltrials.gov
June 30, 2026	NCT07676435	Ongoing Lung Decline With Age Intensified Response	Cedars-Sinai Medical Center	Phase 2	Recruiting	Age-Related Lung Function Decline	40	United States	clinicaltrials.gov
June 29, 2026	NCT07673926	Turkish Adaptation of the Pain and Smoking Inventory	Hacettepe University	Observational	Recruiting	Chronic Pain	200	Turkey (Türkiye)	clinicaltrials.gov
June 29, 2026	NCT07673185	Omega-3 Plus Low-Dose Aspirin in Smokers With Stage III Periodontitis	Al-Azhar University	Not applicable	Recruiting	Periodontal Disease, Periodontitis (Stage 3), Smoking Behaviors	40	Egypt	clinicaltrials.gov
June 25, 2026	NCT07668947	Impact of E-Cigarette Smoking on Healing Response to Non-Surgical Periodontal Therapy	Ain Shams University	Not applicable	Completed	Periodontitis	117	Egypt	clinicaltrials.gov
June 22, 2026	NCT07661823	QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos....	Veterans Recovery Network Inc.	Not applicable	Not yet recruiting	Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism, ADHD - Attention Deficit Disorder With Hyperactivity...	1,000,000	United States	clinicaltrials.gov
June 8, 2026	NCT07631624	Methylated Biomarkers of Smoking as a Selection Tool in Participants for Lung Cancer Screening	University Hospital, Antwerp	Not applicable	Recruiting	Epigenetics, DNA Methylation, Lung Cancer Screening, Risk Stratification With Biomarker, Saliva	1,000	Belgium	clinicaltrials.gov
June 4, 2026	NCT07625111	Effect of Smoking and Time of Day on Eosinophils	Marek Lommatzsch	Not applicable	Recruiting	Healthy	20	Germany	clinicaltrials.gov
May 22, 2026	NCT07604584	Effects of Platelet-Rich Fibrin After Mandibular Third Molar Surgery in Smokers and Nonsmokers	Ankara University	Not applicable	Completed	Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Facial Swelling	30	Turkey (Türkiye)	clinicaltrials.gov
May 22, 2026	NCT07604493	Oral Health and Systemic Diseases: Survey of General Practitioners	University of Roma La Sapienza	Observational	Recruiting	Periodontal Disease, Diabete Mellitus	100	Italy	clinicaltrials.gov
May 22, 2026	NCT07602699	Multi-Site Trial of Tirzepatide for Smoking Cessation	University of Southern California	Phase 2	Recruiting	Smoking Cessation, Smoking Behaviors	300	United States	clinicaltrials.gov
May 20, 2026	NCT07598136	A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers	RAI Services Company	Not applicable	Recruiting	Smoking, Tobacco	1,280	United States	clinicaltrials.gov
May 19, 2026	NCT07595055	Abuse Liability of Two Modern Oral Nicotine Pouched Products	RAI Services Company	Not applicable	Not yet recruiting	Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking	40		clinicaltrials.gov
May 18, 2026	NCT07593742	Smoking Cessation With Wearables to Improve General, Oral Health and Quality of Life	University of Salerno	Not applicable	Not yet recruiting	Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation, Smoking Dependence, Smoking...	102		clinicaltrials.gov
May 7, 2026	NCT07571941	Effects of CO Level on Pain, Sensory Function, and Subjective Health	Izmir Democracy University	Observational	Not yet recruiting	Carbon Monoxide, Pain Perception, Sensory Thresholds, Anxiety, Depression, Tobacco Smoking	70		clinicaltrials.gov
May 6, 2026	NCT07569432	Investigation of Macrophage Polarization in Peri-implant Health and Peri-implantitis	Biruni University	Observational	Recruiting	Peri-implantitis	120	Turkey (Türkiye)	clinicaltrials.gov
May 5, 2026	NCT07568483	TUBSIS 2.0 - Tobacco Use Behavioral Support and Intervention System	University of Zurich	Not applicable	Recruiting	Tobacco Use Disorder, Nicotine Dependence, Vaping, Smoking Tobacco	406	Switzerland	clinicaltrials.gov
May 5, 2026	NCT07566221	Increasing Lung Cancer Screening Among Emergency Department Patients - LCS R01	University of Rochester	Not applicable	Not yet recruiting	Smoking History, Current Smoker, Lung Cancer Screening	1,036		clinicaltrials.gov
May 1, 2026	NCT07562295	Periodontal Health Among Cigarette, Electronic Cigarettes, and Narghile Smokers	Al-Hawash Private University	Observational	Completed	Smokers, Periodontal Status	90	Syria	clinicaltrials.gov
April 30, 2026	NCT07558187	Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants	University of Thessaly	Observational	Recruiting	Non-communicable Diseases (NCD), Addiction to Opioids, Incarceration, Opioid-use Disorders	2,000	Greece	clinicaltrials.gov
April 28, 2026	NCT07553962	Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt	University of Colorado, Denver	Observational	Recruiting	Smoking (Tobacco) Addiction, Smoking ( Cigarette), Tobacco, Tobacco Abstinence, Quitting Smoking, Smoking Cessation	250	United States	clinicaltrials.gov
April 24, 2026	NCT07550491	Influence of Residual Bone Height on Marginal Bone Loss Around Implants Following Lateral Sinus Floor Augmentation With Deproteinized...	Saint-Joseph University	Observational	Completed	Residual Bone Height, Marginal Bone Loss, Implant Type, Smoking, Diabetes	142	Lebanon	clinicaltrials.gov
April 23, 2026	NCT07547202	Effect of Non-Surgical Periodontal Therapy on Salivary Biomarkers in Smokers and Non-Smokers With Periodontitis	Al-Mustansiriyah University	Not applicable	Recruiting	Periodontitis, Smoking ( Cigarette)	44	Iraq	clinicaltrials.gov
April 15, 2026	NCT07530211	The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices	Inonu University	Observational	Completed	Peri-implantitis, Dental Implants, Peri-implant Mucositis	93	Turkey (Türkiye)	clinicaltrials.gov
April 9, 2026	NCT07520981	Functional Capacity, Subjective Dyspnea and Fatigue in Smokers	Istinye University	Observational	Completed	Smoking	103	Turkey (Türkiye)	clinicaltrials.gov
March 30, 2026	NCT07501624	Engaging Pharmacists to Advance Tobacco Treatment Service Delivery	Medical University of South Carolina	Not applicable	Enrolling by invitation	Smoking Cessation, Tobacco Use Disorder, Smoking, HIV, AIDS, Pharmacy	172	United States	clinicaltrials.gov
March 24, 2026	NCT07489443	Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum	University of Pittsburgh	Not applicable	Recruiting	Perinatal, Cannabis Use, Tobacco Use, Smoking Cessation	25	United States	clinicaltrials.gov
March 23, 2026	NCT07488741	Comparison of the Effects of Different Chest Techniques on University Students With Smoking Addiction	University of Yalova	Not applicable	Recruiting	Smoking	30	Turkey (Türkiye)	clinicaltrials.gov
March 23, 2026	NCT07487818	A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation	Mayo Clinic	Phase 2/3	Recruiting	Smoking Cessation	150	United States	clinicaltrials.gov
March 17, 2026	NCT07476144	Nicotine Pouch Pharmacokinetics Abuse Liability	JT International SA	Phase 1	Active not recruiting	Smoking Behaviors	55	United States	clinicaltrials.gov
March 10, 2026	NCT07459621	Evaluation of a Novel mHealth Intervention for People Who Are Ambivalent About Quitting Smoking	Kaiser Permanente	Not applicable	Recruiting	Smoking Behaviors	800	United States	clinicaltrials.gov
March 9, 2026	NCT07457892	Nicotine Dependence, Periodontal Awareness, and Clinical Periodontal Parameters in Smokers With Gingivitis and Periodontitis	Erzincan University	Observational	Completed	Periodontal Disease, Gingivitis and Periodontal Diseases, Periodontitis	350	Turkey (Türkiye)	clinicaltrials.gov
March 2, 2026	NCT07443631	Assessment of HPHC Exposure in Smokers Switching to THS/TP18 With Different Device Variants	Philip Morris Products S.A.	Not applicable	Active not recruiting	Smoking	108	United Kingdom	clinicaltrials.gov
March 2, 2026	NCT07441603	Efficacy of the Proactive Automatized Lifestyle Intervention	University Medicine Greifswald	Not applicable	Recruiting	Health Risk Behaviors, Tobacco Smoking, Alcohol Use, Unhealthy Diet, Exercise, Smoking, and Alcohol Use, Unhealthy...	788	Germany	clinicaltrials.gov
February 24, 2026	NCT07429825	Effect of a Mobile-Based Anti-Smoking Nursing Intervention on Nursing Students (HDDN)	LÜTFİYE GÖKÇE	Not applicable	Completed	Tobacco Abuse Cigarette	43	Turkey (Türkiye)	clinicaltrials.gov
February 23, 2026	NCT07427745	SMOKING AND PRESENCE OF FRANK'S SIGN	Samsun University	Observational	Completed	Smoking ( Cigarette), Cardiovascular Disease	404	Turkey (Türkiye)	clinicaltrials.gov
February 23, 2026	NCT07427706	Effect of Tobacco Use on the Health of the Newborn up to 24 Months.	Institut Investigacio Sanitaria Pere Virgili	Observational	Completed	Apgar Score, Motor Coordination or Function; Developmental Disorder, Lactation, Weight Control, Cardiopulmonary...	105	Spain	clinicaltrials.gov
February 20, 2026	NCT07424443	Pilot Study of a Brain Health Program in Senior Centers	Massachusetts General Hospital	Not applicable	Completed	Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Risk Reduction...	60	United States	clinicaltrials.gov
February 17, 2026	NCT07414355	Switching to E-Cigarettes After Type 2 Diabetes Diagnosis and Health Outcomes	Samsung Medical Center	Observational	Completed	Diabete Type 2, E Cigarette Use, Clinical Outcomes	133,320	South Korea	clinicaltrials.gov
February 17, 2026	NCT07412639	Tabata Exercise on Nitric Oxide Synthases and Maresin	Ataturk University	Not applicable	Completed	Smoking, Smoking, Cigarette	40	Turkey (Türkiye)	clinicaltrials.gov
January 29, 2026	NCT07375459	Community-based Mobile-assisted Brief Intervention for Smoking Cessation	National University of Singapore	Not applicable	Active not recruiting	Smoking &Amp; Tobacco Cessation	100	Singapore	clinicaltrials.gov
January 16, 2026	NCT07348679	Cigarette Filter Study	Rutgers, The State University of New Jersey	Not applicable	Recruiting	Smoking ( Cigarette)	252	United States	clinicaltrials.gov
January 15, 2026	NCT07342920	Study of the Prevalence of Active/Passive Smoking and Vaping Among Patients With Cystic Fibrosis	University Hospital, Strasbourg, France	Observational	Recruiting	Cystic Fibrosis	100	France	clinicaltrials.gov
January 15, 2026	NCT07341945	Oral Health Literacy and Periodontal Status Among Turkish Adults	Biruni University	Observational	Completed	Periodontal Diseases, Oral Health Literacy, Periodontitis, Health Behaviour, Health Education	108	Turkey (Türkiye)	clinicaltrials.gov
January 13, 2026	NCT07338318	Effects of E-Cigarette Use on Oxidative Stress and Matrix Degradation	Ankara Medipol University	Observational	Completed	Smoking Behaviors, Periodontal Health	60	Turkey (Türkiye)	clinicaltrials.gov
January 9, 2026	NCT07328594	Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking	Legacy Health System	Phase 4	Not yet recruiting	Smoking, Nicotine, Tobacco, Addiction, Substance Use Disorders, Insomnia, Sleep	44	United States	clinicaltrials.gov
January 7, 2026	NCT07323563	A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems	RAI Services Company	Not applicable	Not yet recruiting	Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking	40		clinicaltrials.gov
January 7, 2026	NCT07323511	Abuse Liability for Eight Electronic Nicotine Products	RAI Services Company	Not applicable	Not yet recruiting	Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking	70		clinicaltrials.gov
January 7, 2026	NCT07323277	Effect of Smoking on Macrophage Polarization in Periodontitis	Suleyman Demirel University	Observational	Completed	Periodontitis	80	Turkey (Türkiye)	clinicaltrials.gov
January 7, 2026	NCT07322796	Smoking Cessation Before Bronchoscopy or CT-guided Puncture	RWTH Aachen University	Observational	Recruiting	Pulmonary Nodule, Solitary, Smoking Behaviors	25	Germany	clinicaltrials.gov
January 2, 2026	NCT07314957	Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial	University of Zadar	Not applicable	Not yet recruiting	Metabolic Syndrome, Inactivity/Low Levels of Exercise, Unhealthy Diet, Unhealthy Alcohol Use, Smoking Behaviors...	120	Croatia	clinicaltrials.gov
December 31, 2025	NCT07312552	Association of Periodontal Status and Smoking With Salivary Inflammasome Markers	Uskudar University	Observational	Recruiting	Periodontitis, Periodontal Disease, Periodontal Health, Smoking, Inflammasomes	116	Turkey (Türkiye)	clinicaltrials.gov
December 30, 2025	NCT07309484	Lifestyle and Its Association With Maintaining Health	University of Zadar	Observational	Enrolling by invitation	Lifestyle (Sedentary Behavior and Physical Activity), Mental Health, Nutrition, Sleep, Stress, Unhealthy Diet...	2,500	Croatia	clinicaltrials.gov
December 24, 2025	NCT07301151	PASCAL Feasibility Study	University of Minnesota	Not applicable	Recruiting	Smoking Cessation, Smoking (Tobacco) Addiction	120	United States	clinicaltrials.gov
December 22, 2025	NCT07295756	The Role of Smoking in Periodontal Status	Tuğba ŞAHİN	Observational	Completed	Periodontal Diseases	484	Turkey (Türkiye)	clinicaltrials.gov
December 15, 2025	NCT07282756	Evaluation Of The Efficacy Of Subgingival Application Of Lovastatin Gel As An Adjunct To Non-Surgical Treatment Of Periodontitis In...	Medical University of Silesia	Not applicable	Recruiting	Periodontal Diseases, Periodontitis, Periodontal Disease, Smokers	44	Poland	clinicaltrials.gov
December 12, 2025	NCT07279896	Determination of RNA/DNA Damage Associated With Oxidative Stress in Periodontitis Patients	Zehra Hasgül	Observational	Completed	Periodontitis (Stage 3), Smoking	88	Turkey (Türkiye)	clinicaltrials.gov
December 5, 2025	NCT07267195	Abuse Liability for Four Heated Tobacco Product (HTP) Consumables and Two HTP Devices	RAI Services Company	Not applicable	Not yet recruiting	Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking	40		clinicaltrials.gov
December 3, 2025	NCT07262606	Salivary Mitofusin-1 Levels in Periodontitis: Associations With Disease Severity, Smoking, and Treatment Response	Ömer Faruk Okumuş	Not applicable	Completed	Periodontal Disease, Chronic Periodontitis (Disorder)	104	Turkey (Türkiye)	clinicaltrials.gov
November 3, 2025	NCT07223840	A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse	Eli Lilly and Company	Phase 2	Recruiting	Smoking	222	China, Japan, United States	clinicaltrials.gov
October 27, 2025	NCT07221214	GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV	Vanderbilt University Medical Center	Phase 2	Recruiting	HIV, Alcohol, Smoking Cigarette, Cardiovascular Disease Prevention	200	United States	clinicaltrials.gov
October 9, 2025	NCT07214168	Vape Use Among Younger & Older Smokers	Abramson Cancer Center at Penn Medicine	Observational	Completed	Smoking Cigarette, Smoking Behaviors, Vaping, Vaping Behaviors	62	United States	clinicaltrials.gov
October 9, 2025	NCT07213752	Diode Laser-Assisted Periodontal Therapy Enhances Clinical Outcomes for Deep Periodontal Pockets in Smokers	Selcuk University	Not applicable	Completed	Periodontitis, Periodontitis Stage III, Periodontal Disease, Diode Laser Therapy, Smoking, Malondialdehyde	33	Turkey (Türkiye)	clinicaltrials.gov
October 1, 2025	NCT07200895	Acute IMT Intensity Effects in Male Smokers	FATMA DİLARA AKAR ÇAMYAR	Not applicable	Completed	Smokers	34	Turkey (Türkiye)	clinicaltrials.gov
September 22, 2025	NCT07186049	Impact of Exercise Associated With Cognitive-behavioral Therapy in Smokers	Agnaldo José Lopes	Not applicable	Not yet recruiting	Smoking (Tobacco) Addiction	66	Brazil	clinicaltrials.gov
September 17, 2025	NCT07178899	Designing a Smoking Intervention for Youth Smokers	The University of Hong Kong	Not applicable	Not yet recruiting	Smoking (Tobacco) Addiction, Young Adult, RCT	100	Hong Kong	clinicaltrials.gov
September 15, 2025	NCT07173335	Integrated Healthy Lifestyle and Pain Care for People With Musculoskeletal Conditions Living in Rural Areas.	University of Sydney	Not applicable	Recruiting	Musculoskeletal Pain, Osteoarthritis, Low Back Pain	354	Australia	clinicaltrials.gov
September 15, 2025	NCT07172438	A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers	RAI Services Company	Not applicable	Terminated	Smoking, Tobacco	668	United States	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
RAI Services Company	13	October 20, 2026
University of Minnesota	4	December 24, 2025
Massachusetts General Hospital	3	August 27, 2026
Georgia State University	3	August 24, 2026
Medical University of South Carolina	3	August 10, 2026
Ankara University	2	October 27, 2026
Inonu University	2	August 14, 2026
Zehra Hasgül	2	August 14, 2026
VA Office of Research and Development	2	July 20, 2026
University of Southern California	2	July 13, 2026
Biruni University	2	May 6, 2026
University of Rochester	2	May 5, 2026
Mayo Clinic	2	March 23, 2026
Philip Morris Products S.A.	2	March 2, 2026
Rutgers, The State University of New Jersey	2	January 16, 2026
University of Zadar	2	January 2, 2026
The University of Hong Kong	2	September 17, 2025
Virginia Polytechnic Institute and State University	2	July 30, 2025
British University In Egypt	1	November 4, 2026
Clinique de la Mitterie	1	November 2, 2026

By phase

Phase	New trials	Latest
Not applicable	93	November 2, 2026
Observational	49	November 4, 2026
Phase 2	7	August 10, 2026
Phase 4	4	January 9, 2026
Phase 3	2	August 14, 2026
Phase 1	2	March 17, 2026
Phase 2/3	1	March 23, 2026

By country

Country	New trials	Latest
United States	59	October 19, 2026
Turkey (Türkiye)	34	October 27, 2026
France	5	November 2, 2026
Egypt	4	November 4, 2026
Germany	4	June 4, 2026
Switzerland	3	October 6, 2026
United Kingdom	3	March 2, 2026
Poland	3	December 15, 2025
China	3	November 3, 2025
Italy	2	May 22, 2026
Spain	2	February 23, 2026
Croatia	2	January 2, 2026
Japan	2	November 3, 2025
Hong Kong	2	September 17, 2025
Thailand	1	October 19, 2026
Mexico	1	September 18, 2026
Bangladesh	1	August 5, 2026
Belgium	1	June 8, 2026
Syria	1	May 1, 2026
Greece	1	April 30, 2026
Lebanon	1	April 24, 2026
Iraq	1	April 23, 2026
South Korea	1	February 17, 2026
Singapore	1	January 29, 2026
Brazil	1	September 22, 2025

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.