Data / New clinical trials / Shock, Septic

New Shock, Septic clinical trials: 168 posted since Nov 2024

Name: New Shock, Septic clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Shock, Septic clinical trials: 168 rows for $8.40, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 8 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (sponsor class, condition groups (MeSH), interventions, start date, enrollment type, location countries and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/shock-septic, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 9, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

168 clinical studies in Shock, Septic were first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026; 4 have an industry sponsor and 123 are recruiting or about to. The newest, NCT07924501, was posted on November 9, 2026: AI-ECHO Hemodynamic Phenotyping in Septic Shock (Second Affiliated Hospital of Guangzhou Medical University).

The request: Every new Shock, Septic clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

168New trials
4Industry sponsored
123Recruiting or not yet
November 9, 2026Latest posted

Newest trials

The newest 100 of 168, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 9, 2026	NCT07924501	AI-ECHO Hemodynamic Phenotyping in Septic Shock	Second Affiliated Hospital of Guangzhou Medical University	Observational	Not yet recruiting	Sepsis, Septic Shock, Septic Cardiomyopathy	240	China	clinicaltrials.gov
November 6, 2026	NCT07922954	Thymosin Alpha 1 and IgM Levels in Sepsis	Southeast University, China	Phase 4	Active not recruiting	Sepsis, Septic Shock	36	China	clinicaltrials.gov
November 3, 2026	NCT07913464	PF-Organized Corticosteroid-Associated Heterogeneity in Sepsis	Shanghai Zhongshan Hospital	Observational	Completed	Sepsis, Critical Illness	2,693	China	clinicaltrials.gov
October 30, 2026	NCT07906561	Serum GDF-15 and LGALS3BP as Prognostic Biomarkers in Sepsis	Inonu University	Observational	Not yet recruiting	Sepsis, Septic Shock	150		clinicaltrials.gov
October 27, 2026	NCT07898462	A Trial of Adjunctive Fludrocortisone (50mcg, 100mcg or Placebo) in Critically Ill Patients With Septic Shock Receiving Hydrocortisone...	The George Institute	Phase 3	Recruiting	Septic Shock	2,200	Australia	clinicaltrials.gov
October 26, 2026	NCT07896018	Clinical Value of EMR3 in Sepsis Diagnosis, Monitoring, and Prognosis: A Multicenter Prospective Observational Study	Sir Run Run Shaw Hospital	Observational	Recruiting	Sepsis	3,000	China	clinicaltrials.gov
October 22, 2026	NCT07888036	Neutrophil Activation and NETosis in Sepsis	Assiut University	Observational	Not yet recruiting	Sepsis, Septic Shock	85		clinicaltrials.gov
October 16, 2026	NCT07879287	Internal Jugular Vein and Inferior Vena Cava Collapsibility Indices as a Guidance of Fluid Responsiveness in Septic Shock Cancer Patients	Cairo University	Observational	Completed	Internal Jugular Vein, Inferior Vena Cava, Collapsibility Indices, Fluid Responsiveness, Septic Shock, Cancer	106	Egypt	clinicaltrials.gov
October 13, 2026	NCT07871305	Core-to-Big-Toe Temperature Gradient as a Marker of Peripheral Perfusion in Adult Patients With Septic Shock	Assiut University	Observational	Not yet recruiting	Septic Shock, Sepsis	54		clinicaltrials.gov
October 8, 2026	NCT07865585	HOPE-Sepsis: Hemoadsorption Therapy for Sepsis	Shanghai Zhongshan Hospital	Not applicable	Not yet recruiting	Sepsis and Septic Shock	30	China	clinicaltrials.gov
October 8, 2026	NCT07864818	Sepsis ICU Gut Microbiome Analysis	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Observational	Not yet recruiting	Sepsis, Septic Shock	180	China	clinicaltrials.gov
October 7, 2026	NCT07863323	Non-invasive Hemodynamic Optimization of Sepsis in Internal Medicine: a Randomized Study Comparing Therapy Guided by Non-invasive...	Regione del Veneto - AULSS n. 7 Pedemontana	Not applicable	Recruiting	Sepsis, Septic Shock	430	Italy	clinicaltrials.gov
September 16, 2026	NCT07822412	PRIME Sepsis Trial: Early Sepsis Detection in the Emergency Department Using Presepsin and Immature Granulocytes	Chang Gung Memorial Hospital	Observational	Not yet recruiting	Sepsis, Septic Shock	699	Taiwan	clinicaltrials.gov
September 15, 2026	NCT07820267	Dynamic POCUS of Diaphragm Function to Predict Respiratory Failure in Septic Shock	Assiut University	Observational	Not yet recruiting	Respiration Failure, Diaphragmatic Dysfunction, Mechanical Ventilation, Septic Shock	120	Egypt	clinicaltrials.gov
September 15, 2026	NCT07819708	Comparing Blood-Based Ratios for Predicting Outcomes in Sepsis and Septic Shock	Benha University	Observational	Completed	Sepsis, Septic Shock	60	Egypt	clinicaltrials.gov
September 14, 2026	NCT07817043	Microbiology Operations & Time Optimization in Sepsis	University Medicine Greifswald	Observational	Not yet recruiting	Sepsis, Bloodstream Infection, Bacterial Infections, Septic Shock, Bacteremia	1,000	Germany	clinicaltrials.gov
September 10, 2026	NCT07812051	Ionized Calcium as a Severity Marker in Septic Shock Patients	Assiut University	Observational	Not yet recruiting	Sepsis, Septic Shock, Hypocalcemia	160		clinicaltrials.gov
September 9, 2026	NCT07811180	Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care Unit	Vanderbilt University Medical Center	Not applicable	Not yet recruiting	Glucose, Metabolism, Isotope Labeling, Immune System and Related Disorders, Critical Illness, Intensive Care Unit...	25	United States	clinicaltrials.gov
September 8, 2026	NCT07807410	Early Endotoxin Burden Reduction With oXiris in Septic Shock Patients Requiring CRRT	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Not applicable	Recruiting	Septic Shock, Acute Kidney Injury	13	China	clinicaltrials.gov
September 1, 2026	NCT07797751	This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure...	Ain Shams University	Observational	Not yet recruiting	Septic Shock, Fluid Reponsiveness	30		clinicaltrials.gov
August 26, 2026	NCT07786350	Thiamine, Ascorbic Acid, and Their Combination on MMP-9/TIMP-1 and Inflammatory Balance in Sepsis	Universitas Sumatera Utara	Not applicable	Completed	Sepsis and Septic Shock	40	Indonesia	clinicaltrials.gov
August 21, 2026	NCT07779720	Personalized Fluid Resuscitation in the Emergency Department: A Pilot Trial	Intermountain Health Care, Inc.	Not applicable	Recruiting	Sepsis, Septic Shock	40	United States	clinicaltrials.gov
August 21, 2026	NCT07778004	ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their Caregivers	University of North Carolina, Chapel Hill	Not applicable	Not yet recruiting	Acute Respiratory Failure, Critical Illness, Sepsis, Hypoxia, Hypercapnia	144	United States	clinicaltrials.gov
August 19, 2026	NCT07775001	Dopamine Versus Epinephrine for Pediatric Fluid-Refractory Hypotensive Septic Shock	Nishtar Medical University	Not applicable	Active not recruiting	Septic Shock	66	Pakistan	clinicaltrials.gov
August 19, 2026	NCT07774962	Discordance Between Capillary Refill Time and Oxygen Extraction Ratio in Septic Shock	Istanbul University - Cerrahpasa	Observational	Recruiting	Septic Shock, Sepsis	100	Turkey (Türkiye)	clinicaltrials.gov
August 12, 2026	NCT07760415	EEG Changes and Cognitive Profiles in Sepsis Patients With Different Inflammatory Phenotypes	Xiangya Hospital of Central South University	Observational	Not yet recruiting	Sepsis, Sepsis Associated Encephalopathy, Sepsis and Septic Shock, Sepsis at Intensive Care Unit	78	China	clinicaltrials.gov
August 4, 2026	NCT07746050	Value of Biomarkers of Brain Injury for Predicting Psycho-cognitive Sequelae Secondary to Sepsis: a Prospective Multicenter Study	Assistance Publique - Hôpitaux de Paris	Not applicable	Not yet recruiting	Sepsis, Septic Shock	210	France	clinicaltrials.gov
July 30, 2026	NCT07735741	Immune Dysregulation During Sepsis: A Natural History Cohort	National Heart, Lung, and Blood Institute (NHLBI)	Observational	Not yet recruiting	Sepsis, Septic Shock, Sepsis-Associated Immune Dysregulation	500	United States	clinicaltrials.gov
July 29, 2026	NCT07733206	Validation of a Capillary Leak Index During Septic Shock, Based on Haemoglobin Level Variations Induced by Fluid Resuscitation. A Pilot...	University Hospital Center of Martinique	Not applicable	Not yet recruiting	Sepsis	100	Martinique	clinicaltrials.gov
July 23, 2026	NCT07721974	Alterations of the Renin-angiotensin-aldosterone System in sEptic Shock	Assistance Publique - Hôpitaux de Paris	Not applicable	Not yet recruiting	Septic Shock	320		clinicaltrials.gov
July 21, 2026	NCT07716956	Effect of Targeting Upper Normal Serum Magnesium Levels on Norepinephrine Requirements in Septic Shock Patients	Alexandria University	Not applicable	Recruiting	Septic Shock, Sepsis	60	Egypt	clinicaltrials.gov
July 20, 2026	NCT07715110	Biological Effects of Hemoadsorption in Septic Shock	Miguel Sanchez Garcia	Not applicable	Not yet recruiting	Septic Shock, Vasopressor Resistance, Multiple Organ Dysfunction, Sepsis, Hemoperfusion, Hemoadsorption	16	Spain	clinicaltrials.gov
July 17, 2026	NCT07711405	Association of Arterio-Venous Oxygen and Carbon Dioxide Gradients With Tissue Hypoperfusion and Mortality in Sepsis	Gaziosmanpasa Research and Education Hospital	Observational	Completed	Intubated ICU Patients, Sepsis and Septic Shock	88	Turkey (Türkiye)	clinicaltrials.gov
July 17, 2026	NCT07711197	Effects of Hemoadsorption on Vascular Integrity in Septic Shock	Semmelweis University	Not applicable	Not yet recruiting	Septic Shock	110	Hungary	clinicaltrials.gov
July 15, 2026	NCT07706413	Plasma Exchange in Children With Severe Sepsis and Septic Shock	Menoufia University	Not applicable	Recruiting	Severe Sepsis	22	Egypt	clinicaltrials.gov
July 14, 2026	NCT07703592	Comparison of Manual PAOP and Automatic PAOP (Smart Wedge)	Assistance Publique - Hôpitaux de Paris	Observational	Not yet recruiting	Septic Shock	30		clinicaltrials.gov
July 13, 2026	NCT07698834	Splanchnic Perfusion Monitoring in Septic Shock Using Doppler Ultrasound	Assiut University	Observational	Not yet recruiting	Septic Shock	80		clinicaltrials.gov
July 13, 2026	NCT07697144	Effect of Adding Vasopressin on Cardiac Output, Blood Pressure, Diuresis, and Tissue Perfusion Indices in Patients With Septic Shock	Assistance Publique - Hôpitaux de Paris	Observational	Not yet recruiting	Septic Shock and Use of Vasopressin	200	France	clinicaltrials.gov
July 10, 2026	NCT07695337	Continuous Infusion Versus Intermittent Bolus Hydrocortisone in Septic Shock	Benha University	Phase 4	Completed	Septic Shock	110	Egypt	clinicaltrials.gov
July 6, 2026	NCT07685002	Characterizing Perfusion and Congestion Responses to Fluid Loading in Critically Ill Septic Patients	Assistance Publique - Hôpitaux de Paris	Observational	Not yet recruiting	Septic Shock	170	France	clinicaltrials.gov
July 6, 2026	NCT07682766	BioMArkeRs of INflammation, Infection, and Immunity in the Critical Area (MARINA): the Use of Inflammatory and Immunity Biomarkers as Early...	University of Turin, Italy	Observational	Recruiting	Septic Shock, Immunocompromised Patients	200	Italy	clinicaltrials.gov
June 24, 2026	NCT07667153	Myeloid Bias in the Bone Marrow of Septic Patients and Its Correlation With Disease Severity and Prognosis: A Single-Center, Prospective...	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Observational	Not yet recruiting	Sepsis, Septic Shock	45		clinicaltrials.gov
June 22, 2026	NCT07661303	Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety Evaluation	Moscow Multidisciplinary Clinical Center "Kommunarka"	Not applicable	Not yet recruiting	Septic Shock	76	Russia	clinicaltrials.gov
June 18, 2026	NCT07658014	Occult Vasoplegia in Normotensive Sepsis: Early Prediction With Diastolic Index and Lactate	Hospital H+ Queretaro	Observational	Completed	Sepsis, Vasoplegia, Septic Shock	526	Mexico	clinicaltrials.gov
June 18, 2026	NCT07657754	Effects of Esmolol on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock	First Affiliated Hospital of Wannan Medical College	Not applicable	Not yet recruiting	Septic Shock, Sepsis, Critical Illness Sepsis, Severe	20	China	clinicaltrials.gov
June 18, 2026	NCT07657741	Papaverine and Sublingual Microcirculation in Septic Shock	First Affiliated Hospital of Wannan Medical College	Not applicable	Not yet recruiting	Septic Shock, Microcirculatory Dysfunction, Sublingual Microcirculation, Hemodynamic Instability	20	China	clinicaltrials.gov
June 18, 2026	NCT07657715	Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock	First Affiliated Hospital of Wannan Medical College	Not applicable	Not yet recruiting	Septic Shock, Sepsis, Critical Illness	20	China	clinicaltrials.gov
June 18, 2026	NCT07657702	Effects of Anisodamine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock	First Affiliated Hospital of Wannan Medical College	Not applicable	Not yet recruiting	Septic Shock, Sepsis, Critical Illness	20	China	clinicaltrials.gov
June 5, 2026	NCT07630415	EARLY DIAGNOSIS OF SEPTIC DIC	University Hospital, Strasbourg, France	Observational	Not yet recruiting	Disseminated Intravascular Coagulation (DIC), Reanimation, Septic Shock	492	France	clinicaltrials.gov
June 4, 2026	NCT07628023	Comparison of Cardiac Index Measurement Using Right Ventricular Pressure Curve Analysis and Thermodilution Via a Swan-Ganz IQ™ Catheter.	Assistance Publique - Hôpitaux de Paris	Observational	Recruiting	Septic Shock	43	France	clinicaltrials.gov
June 1, 2026	NCT07616817	Delphi Septic Shock: Sub-phenotypes Using Point-of-Care Ultrasound in Patients With Septic Shock	Albany Medical College	Observational	Enrolling by invitation	Septic Shock, Sepsis, Shock	50	United States	clinicaltrials.gov
May 22, 2026	NCT07603024	Effect of Shenfu Injection on the Vascular Waterfall Phenomenon in Patients With Septic Shock	First Affiliated Hospital of Wannan Medical College	Not applicable	Not yet recruiting	Septic Shock	20	China	clinicaltrials.gov
May 19, 2026	NCT07597122	MIRNA QUANTIFICATION IN PATIENTS WITH SEPTIC SHOCK	Insel Gruppe AG, University Hospital Bern	Observational	Recruiting	Sepsis and Septic Shock	56	Switzerland	clinicaltrials.gov
May 15, 2026	NCT07591402	Metformine as a Protective Factor of Mortality in Type 2 Diabetic Patients Admitted to the ICU for Septic Shock.	Assistance Publique - Hôpitaux de Paris	Observational	Completed	D012139, D003924	2,740	France	clinicaltrials.gov
May 14, 2026	NCT07585942	Fluorescent Leukocytes as a Marker of Early Sepsis/Severity	University Hospital, Strasbourg, France	Observational	Not yet recruiting	Sepsis, Disseminated Intravascular Coagulation (DIC), Septic Shock	492	France	clinicaltrials.gov
May 13, 2026	NCT07582926	Cortisol Levels and Mortality in Septic Shock ICU Patients	Ankara Etlik City Hospital	Observational	Recruiting	Sepsis, Septic Shock	183	Turkey (Türkiye)	clinicaltrials.gov
May 11, 2026	NCT07578558	NAI for Sepsis With Persistent Lymphopenia	ImmunityBio, Inc.	Phase 2	Not yet recruiting	Sepsis, Septic Shock, Lymphopenia, Immunosuppression, Critical Illness	50		clinicaltrials.gov
May 6, 2026	NCT07569536	Efficacy of the Alpha 2 Agonist Dexmedetomidine for Sympathetic Deactivation in REfractory Septic Shock	Hospices Civils de Lyon	Phase 3	Not yet recruiting	Septic Shock, Vasopressor Resistance	360	France	clinicaltrials.gov
May 6, 2026	NCT07569406	Use of Oxiris Filter in Septic Shock Patients Requiring Renal Replacement Therapy: A Retrospective Cohort Study	Clinica Universidad de Navarra, Universidad de Navarra	Observational	Completed	Septic Shock, Acute Kidney Injury	400	Spain	clinicaltrials.gov
May 5, 2026	NCT07568275	Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance	The Cleveland Clinic	Early phase 1	Active not recruiting	Septic Shock, Cirrhosis, Vasodilatory Shock, Acute Kidney Injury	30	United States	clinicaltrials.gov
May 4, 2026	NCT07565649	Impact of Systematic Point-of-Care Ultrasound Implementation on Clinical Outcomes and Survival in Septic Shock: A Retrospective...	Clinica Universidad de Navarra, Universidad de Navarra	Observational	Completed	Septic Shock, Sepsis	200	Spain	clinicaltrials.gov
April 24, 2026	NCT07550400	Role of Echocardiography and Ultrasound Indices in Resuscitation of Septic Shock Patients	Ain Shams University	Observational	Recruiting	Septic Shock, Fluid Resuscitation	40	Egypt	clinicaltrials.gov
April 20, 2026	NCT07539883	Effect of oXiris Hemofilter Use in Septic Shock: A Multicenter Retrospective Cohort Study	Seoul National University Bundang Hospital	Observational	Recruiting	Septic Shock, Multiorgan Failure, Sepsis	360	South Korea	clinicaltrials.gov
April 15, 2026	NCT07530146	Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive...	Helwan University	Phase 3	Active not recruiting	The Critically Ill Patient is Requiring Intubation, Septic Shock, Pneumonia	70	Egypt	clinicaltrials.gov
April 7, 2026	NCT07516236	Dynamic SvO2 in Predicting Fluid Responsiveness in Septic Shock	Menoufia University	Observational	Recruiting	Sepsis and Septic Shock	115	Egypt	clinicaltrials.gov
March 25, 2026	NCT07492030	Validation of the Use of the Arteriovenous Tension Difference in CO2 Under Hyperbaric Conditions	University Hospital, Lille	Observational	Not yet recruiting	Necrotizing Fascitis, Cellulitis, Septic Shock	74	France	clinicaltrials.gov
March 23, 2026	NCT07488689	Assessing the Efficacy of Dapagliflozin as a Vasculoprotective Treatment in Septic Shock Patients With Microcirculatory Dysfunction	University Hospital, Strasbourg, France	Phase 3	Not yet recruiting	Septic Shock	568	France	clinicaltrials.gov
March 19, 2026	NCT07483710	Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission and 3 Months...	Centre Hospitalier Universitaire de Saint Etienne	Not applicable	Recruiting	Septic Shock	196	France	clinicaltrials.gov
March 13, 2026	NCT07470775	Early Dexmedetomidine and Sympathetic Regulation in Sepsis	Sichuan Academy of Medical Sciences	Phase 4	Not yet recruiting	Sepsis, Septic Shock	168		clinicaltrials.gov
March 10, 2026	NCT07460024	Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality...	Al-Azhar University	Not applicable	Completed	Sepsis, Septic Shock, Systemic Inflammatory Response Syndrome (SIRS), Critical Illness	120	Saudi Arabia	clinicaltrials.gov
March 6, 2026	NCT07453901	The Multicentre Prospective Observational Study on the Management of Septic Shock	Bicetre Hospital	Observational	Not yet recruiting	Septic Shock	5,000		clinicaltrials.gov
March 5, 2026	NCT07451886	Adjunctive Fludrocortisone in Septic Shock	Chinese University of Hong Kong	Phase 2	Recruiting	Sepsis, Septic Shock, Sepsis - to Reduce Mortality in the Intensive Care Unit, Sepsis and Septic Shock, Sepsis at...	32	Hong Kong	clinicaltrials.gov
March 2, 2026	NCT07442032	Cardiovascular Phenotypes in Sepsis	Karolinska Institutet	Observational	Not yet recruiting	Sepsis, Septic Shock, Cardiovascular Dysfunction, Microcirculatory Dysfunction, Troponin Elevation, Peripheral Vascular...	400		clinicaltrials.gov
February 27, 2026	NCT07438301	Septic Shock Hemodynamic Respond to Volume Resuscitation Versus Vasopressor Administration	Mahidol University	Observational	Not yet recruiting	Septic Shock	180	Thailand	clinicaltrials.gov
February 23, 2026	NCT07425587	Multicenter Symphony™ IL-6 Monitoring Sepsis ED Pilot Study	Bluejay Diagnostics, Inc.	Observational	Active not recruiting	Sepsis, Septic Shock	450	United States	clinicaltrials.gov
February 19, 2026	NCT07419802	OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study	Pauls Stradins Clinical University Hospital	Observational	Recruiting	Sepsis, Septic Shock, Blood Purification, Hemoadsorption	29	Latvia	clinicaltrials.gov
February 18, 2026	NCT07418541	Early Co-Administration of Crystalloid Fluid and Norepinephrine for Preventing Acute Kidney Injury in Septic Shock	Universitas Sumatera Utara	Not applicable	Not yet recruiting	Septic Shock, Acute Kidney Injury	100		clinicaltrials.gov
February 17, 2026	NCT07415096	Written Sepsis Education for Patients	McMaster University	Not applicable	Not yet recruiting	Sepsis, Sepsis and Septic Shock, Sepsis at Intensive Care Unit	30		clinicaltrials.gov
February 17, 2026	NCT07412366	Urea-to-Creatinine Ratio as a Marker of Metabolic Transition in Septic Shock: A Comparison With Indirect Calorimetry	Hospital Sao Domingos	Observational	Not yet recruiting	Septic Shock	40		clinicaltrials.gov
February 13, 2026	NCT07411469	Comparison Between Using Cardiometry and IVC Collapsibility	Menoufia University	Observational	Recruiting	Septic Shock	60	Egypt	clinicaltrials.gov
February 12, 2026	NCT07406750	Hemodynamic Venous Congestion Ultrasound (VExUS) by ICU Nurses in Sepsis Patients.	Region Örebro County	Observational	Not yet recruiting	Sepsis, Sepsis and Septic Shock, Sepsis at Intensive Care Unit, Intensive Care Nurses	46		clinicaltrials.gov
February 10, 2026	NCT07401329	Early and Late Neutrophil CD64 and Monocyte HLA-DR as Biomarkers for Septic Shock	Pandit Bhagwat Dayal Sharma, PGIMS, Rohtak	Observational	Completed	Sepsis, Septic Shock	76	India	clinicaltrials.gov
February 10, 2026	NCT07398703	Extended vs. Intermittent Meropenem Infusion in Sepsis Patients in the ICU	Assiut University	Observational	Not yet recruiting	Sepsis, Septic Shock	90		clinicaltrials.gov
February 5, 2026	NCT07388628	ARTICE® Real Data Collection & Observational Trial, Phase 4 Study	Artcline GmbH	Observational	Recruiting	Sepsis, Septic Shock, Immunoparalysis in Septic Shock	200	Germany	clinicaltrials.gov
February 3, 2026	NCT07383103	Hydrocortisone and Fludrocortisone for the Treatment of Septic Shock	Northern Jiangsu People's Hospital	Phase 4	Recruiting	Septic Shock	336	China	clinicaltrials.gov
January 27, 2026	NCT07370753	Early Continuous Renal Replacement Therapy for Pediatric Septic Shock	National Children's Hospital, Vietnam	Observational	Active not recruiting	Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome, Septic Shock	50	Vietnam	clinicaltrials.gov
January 27, 2026	NCT07369206	ICU Admission Diagnoses and ICU Mortality	Ataturk University	Observational	Completed	Critical Illness, Sepsis, Septic Shock, Acute Respiratory Distress Syndrome (ARDS), Acute Respiratory Failure, Multiple...	1,248	Turkey (Türkiye)	clinicaltrials.gov
January 26, 2026	NCT07367113	Peripheral Perfusion Index-guided Fluid Resuscitation for Preventing Acute Skin Failure in Elderly Critically Ill Patients	Ying Wang	Not applicable	Recruiting	Sepsis, Septic Shock, Acute Skin Failure	216	China	clinicaltrials.gov
January 21, 2026	NCT07354568	Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock	Centre Hospitalier Universitaire, Amiens	Observational	Recruiting	Cardiogenic Shock Acute, Bypass, Cardiopulmonary, Septic Shock, Mechanical Circulatory Support, Myocardial Infarction...	2,500	France	clinicaltrials.gov
January 15, 2026	NCT07343206	Early Norepinephrine Administration and Rapid Dose Adjustment	Siriraj Hospital	Not applicable	Recruiting	Sepsis, Septic Shock	600	Thailand	clinicaltrials.gov
January 12, 2026	NCT07334327	Extracorporeal Blood Purification Using Oxiris for Septic Shock (EXPLORE Study)	Pusan National University Yangsan Hospital	Not applicable	Not yet recruiting	Septic Shock, Multi Organ Failure	62		clinicaltrials.gov
January 9, 2026	NCT07330908	Different Norepinephrine Doses on Accuracy of Peripheral Perfusion Index in Predicting Tissue Perfusion in Septic Shock Patients	Tanta University	Not applicable	Completed	Septic Shock, Peripheral Perfusion Index	80	Egypt	clinicaltrials.gov
January 7, 2026	NCT07321405	Assessment of Cardiac Output and Stroke Volume in Septic Shock Patients	Assiut University	Observational	Not yet recruiting	Septic Shock	100	Egypt	clinicaltrials.gov
January 2, 2026	NCT07313670	Outcome of Using Hydrocortisone in Early Treatment of Pediatric Septic Shock	Muhammad Aamir Latif	Not applicable	Completed	Septic Shock	122	Pakistan	clinicaltrials.gov
January 2, 2026	NCT07313605	POCUS-Guided Esmolol in Septic Shock: A Pilot RCT	John Basmaji	Phase 1/2	Not yet recruiting	Septic Shock	100		clinicaltrials.gov
December 31, 2025	NCT07312474	Epidemiological, Clinical and Biological Characteristics of Human Anaplasmosis Cases in Alsace	University Hospital, Strasbourg, France	Observational	Recruiting	Human Anaplasmosis	100	France	clinicaltrials.gov
December 31, 2025	NCT07312071	Vasopressor Use Improves Macrocirculation, But What Are Its Effects on Microcirculation?	Gaziosmanpasa Research and Education Hospital	Not applicable	Completed	Septic Shock, Sepsis, Tissue Ischemia, Hemodynamic Instability	30	Turkey (Türkiye)	clinicaltrials.gov
December 23, 2025	NCT07300306	Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey	Marmara University	Observational	Completed	Sepsis, Septic Shock, Critical Illness, Organ Dysfunction	3,379	Turkey (Türkiye)	clinicaltrials.gov
December 17, 2025	NCT07287332	BLOOM: Pragmatic Feasibility Trial	Mayo Clinic	Not applicable	Recruiting	Sepsis, Infection	300	United States	clinicaltrials.gov
December 16, 2025	NCT07286643	Echocardiography-guided Cirrhosis and Liver Failure-Intensive Care Protocol Sepsis	Post Graduate Institute of Medical Education and Research, Chandigarh	Not applicable	Recruiting	Cirrhosis, Liver, Cirrhotic Cardiomyopathy, Septic Shock	140	India	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Assiut University	8	October 22, 2026
Assistance Publique - Hôpitaux de Paris	8	August 4, 2026
First Affiliated Hospital of Wannan Medical College	8	June 18, 2026
University Hospital, Strasbourg, France	6	June 5, 2026
Ain Shams University	5	September 1, 2026
Centre Hospitalier Universitaire, Amiens	4	January 21, 2026
Menoufia University	3	July 15, 2026
Mahidol University	3	February 27, 2026
Shanghai Zhongshan Hospital	2	November 3, 2026
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	2	October 8, 2026
Benha University	2	September 15, 2026
Universitas Sumatera Utara	2	August 26, 2026
Gaziosmanpasa Research and Education Hospital	2	July 17, 2026
Hospices Civils de Lyon	2	May 6, 2026
Clinica Universidad de Navarra, Universidad de Navarra	2	May 6, 2026
The Cleveland Clinic	2	May 5, 2026
Centre Hospitalier Universitaire de Saint Etienne	2	March 19, 2026
Tanta University	2	January 9, 2026
University Hospital, Rouen	2	June 26, 2025
Gulhane Training and Research Hospital	2	May 6, 2025

By phase

Phase	New trials	Latest
Observational	87	November 9, 2026
Not applicable	51	October 8, 2026
Phase 4	12	November 6, 2026
Phase 3	11	October 27, 2026
Phase 2	3	May 11, 2026
Early phase 1	1	May 5, 2026
Phase 1/2	1	January 2, 2026
Phase 1	1	December 16, 2025
Phase 2/3	1	December 4, 2025

By country

Country	New trials	Latest
France	27	August 4, 2026
China	24	November 9, 2026
Egypt	17	October 16, 2026
Turkey (Türkiye)	14	August 19, 2026
United States	12	September 9, 2026
Spain	6	July 20, 2026
Thailand	4	February 27, 2026
Italy	3	October 7, 2026
Germany	3	September 14, 2026
Pakistan	3	August 19, 2026
Russia	2	June 22, 2026
Mexico	2	June 18, 2026
Switzerland	2	May 19, 2026
Saudi Arabia	2	March 10, 2026
India	2	February 10, 2026
Vietnam	2	January 27, 2026
Brazil	2	December 4, 2025
Canada	2	March 28, 2025
Australia	1	October 27, 2026
Taiwan	1	September 16, 2026
Indonesia	1	August 26, 2026
Martinique	1	July 29, 2026
Hungary	1	July 17, 2026
South Korea	1	April 20, 2026
Hong Kong	1	March 5, 2026

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.