Data / New clinical trials / Scleroderma, Systemic

Scleroderma, Systemic trials: 146 new since Nov 2024

Name: New Scleroderma, Systemic clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Scleroderma, Systemic clinical trials: 146 rows for $7.30, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 7 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (sponsor class, condition groups (MeSH), interventions, start date, enrollment type, location countries and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/scleroderma-systemic, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 9, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

146 clinical studies in Scleroderma, Systemic were first posted on ClinicalTrials.gov from November 20, 2024 to November 9, 2026; 44 have an industry sponsor and 122 are recruiting or about to. The newest, NCT07925619, was posted on November 9, 2026: Efficacy and Safety Study of L608 in Patients With Systemic Sclerosis-associated Digital Ulcers (Pharmosa Biopharm Inc.).

The request: Every new Scleroderma, Systemic clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

Get new trials like these Watch a sponsor

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

146New trials
44Industry sponsored
122Recruiting or not yet
November 9, 2026Latest posted

Newest trials

The newest 100 of 146, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 9, 2026	NCT07925619	Efficacy and Safety Study of L608 in Patients With Systemic Sclerosis-associated Digital Ulcers	Pharmosa Biopharm Inc.	Phase 2	Not yet recruiting	Systemic Sclerosis	40		clinicaltrials.gov
November 9, 2026	NCT07925242	FAPI PET in Systemic Sclerosis Interstitial Lung Disease	University of California, Los Angeles	Phase 2	Not yet recruiting	Systemic Sclerosis (SSc), Scleroderma, Interstitial Lung Disease With Systemic Sclerosis	120	United States	clinicaltrials.gov
November 9, 2026	NCT07924124	Small Airway Dysfunction in Rheumatoid Arthritis and Systemic Sclerosis	Assistance Publique - Hôpitaux de Paris	Not applicable	Not yet recruiting	Rhumatoid Arthisis, Systemic Sclerosis (SSc)	184	France	clinicaltrials.gov
November 4, 2026	NCT07916324	Hyaluronidase Injections for Sclerodactyly in Patients With Scleroderma	Stanford University	Phase 2	Not yet recruiting	Scleroderma, Sclerodactyly, Systemic Sclerosis	10	United States	clinicaltrials.gov
October 30, 2026	NCT07906145	A Phase 1 Study of QLS2416 Injection in Participants With Autoimmune Diseases	Shanghai Qilu Pharmaceutical Research and Development Center LTD	Phase 1	Not yet recruiting	Systemic Lupus Erythematosus, Rheumatoid Arthritis (RA), Primary Sjögren's Syndrome (pSS), Systemic Sclerosis (SSc)	76		clinicaltrials.gov
October 22, 2026	NCT07888842	A Clinical Study on Systemic Sclerosis and the Validation of French-language Questionnaires Assessing Disability, Quality of Life, and...	Assistance Publique - Hôpitaux de Paris	Observational	Not yet recruiting	Scleroderma	200	France	clinicaltrials.gov
October 14, 2026	NCT07873931	A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases	Bristol-Myers Squibb	Phase 1	Not yet recruiting	Systemic Lupus Erythematosus, Sjögren's Disease, Rheumatoid Arthritis, Idiopathic Inflammatory Myopathies, Systemic...	60	Belgium, France, Germany, Netherlands, Poland, United States	clinicaltrials.gov
October 5, 2026	NCT07858838	Using AI-Assisted Cameras to Track Hand Exercises in Scleroderma Patients	Istanbul University - Cerrahpasa	Not applicable	Not yet recruiting	Systemic Scleroderma	40	Turkey (Türkiye)	clinicaltrials.gov
October 2, 2026	NCT07854483	C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory...	AbelZeta Inc.	Phase 1	Not yet recruiting	Systemic Sclerosis (SSc), Systemic Sclerosis, Systemic Sclerosis (Scleroderma), Systemic Sclerosis - 2013 ACR/EULAR...	12	United States	clinicaltrials.gov
September 25, 2026	NCT07842523	Obinutuzumab in Systemic Sclerosis	Assistance Publique - Hôpitaux de Paris	Phase 2	Not yet recruiting	Systemic Sclerosis in Adults	120	France	clinicaltrials.gov
September 25, 2026	NCT07842133	The Effect of Progressive Muscle Relaxation Exercises on Fatigue, Dyspnea, and Respiratory Function in Patients With Systemic Sclerosis	University of Gaziantep	Not applicable	Recruiting	Systemic Sclerosis (SSc)	50	Turkey (Türkiye)	clinicaltrials.gov
September 25, 2026	NCT07840430	Home-based Exercise for Improving Health-related Quality of Life in Systemic Sclerosis	University of Aarhus	Not applicable	Not yet recruiting	Systemic Sclerosis (SSc)	270	Denmark	clinicaltrials.gov
September 24, 2026	NCT07839221	Combined Growth Differentiation Factor-15 (GDF-15) and Lung Ultrasound for ILD Screening in Rheumatoid Arthritis and Systemic Sclerosis	Assiut University	Observational	Not yet recruiting	Rheumatoid Arthritis (RA), Systemic Sclerosis (SSc), Interstitial Lung Disease (ILD)	110		clinicaltrials.gov
September 24, 2026	NCT07837986	Investigation of Type I Interferon Excess in Patients With Systemic Autoimmune Diseases and Genetic Type I Interferonopathies	Hospices Civils de Lyon	Not applicable	Not yet recruiting	Systememic Lupus Erythematosus, Systemic Sclerosis (SSc), Inflammatory Myopathies, Connective Tissue Diseases, Type 1...	120	France	clinicaltrials.gov
September 23, 2026	NCT07836361	Clinical Cohort Study of Systemic Sclerosis	Peking University Third Hospital	Observational	Recruiting	Sclerosis, Systemic	150	China	clinicaltrials.gov
September 18, 2026	NCT07827742	Rituximab vs Placebo for Maintenance in Systemic Sclerosis - Interstitial Lung Disease	Assistance Publique - Hôpitaux de Paris	Phase 2	Not yet recruiting	Systemic Sclerosis in Adults	120	France	clinicaltrials.gov
September 15, 2026	NCT07821398	Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic Sclerosis	Bastiaan Driehuys	Phase 2	Not yet recruiting	Interstitial Lung Disease, Pulmonary Hypertension, Systemic Sclerosis	51		clinicaltrials.gov
September 8, 2026	NCT07806045	Nebulized UC-EVs for Recurrent or Refractory IMIDs With Lung Involvement	Qiubai Li	Early phase 1	Not yet recruiting	IgG4 Related Disease, Systemic Sclerosis (SSc)	18	China	clinicaltrials.gov
September 2, 2026	NCT07800871	FT839 in Autoimmune Diseases	Fate Therapeutics	Phase 1/2	Recruiting	ANCA-Associated Vasculitis (AAV), Idiopathic Inflammatory Myositis (IIM), Rheumatoid Arthritis (RA), Systemic Lupus...	446	United States	clinicaltrials.gov
August 24, 2026	NCT07782450	A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases	Pfizer	Phase 1/2	Not yet recruiting	Systemic Lupus Erythematosus, Rheumatoid Arthritis, Idiopathic Inflammatory Myositis, Systemic Sclerosis	54		clinicaltrials.gov
August 21, 2026	NCT07778446	A Study to Test CRT-402 in Refractory Autoimmune Disease	Myeloid Therapeutics	Phase 1/2	Recruiting	Autoimmune Diseases, Systemic Lupus Erythematosus, Systemic Scleroderma, Myositis	34	Australia	clinicaltrials.gov
August 12, 2026	NCT07759557	Efficacy of A Non-Invasive Botulinum Toxin Microneedle Pad for the Treatment of Secondary Raynaud's Phenomenon	Khon Kaen University	Phase 3	Not yet recruiting	Systemic Sclerosis (SSc), Raynaud Disease Secondary to Scleroderma	72		clinicaltrials.gov
August 5, 2026	NCT07748000	A Study of LIQ861 (Inhaled Treprostinil) in Adults With Systemic Sclerosis Who Have Symptomatic Raynaud's Phenomenon Attacks	Liquidia Technologies, Inc.	Phase 2	Not yet recruiting	Raynaud's Phenomenon Secondary to Systemic Sclerosis	75		clinicaltrials.gov
August 4, 2026	NCT07745725	A Phase II Study of TollB-001 Tablets in Systemic Sclerosis	Toll Biotech Co. Ltd. (Beijing)	Phase 2	Not yet recruiting	Systemic Sclerosis (SSc)	36	China	clinicaltrials.gov
July 30, 2026	NCT07737470	Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research	Assistance Publique - Hôpitaux de Paris	Observational	Not yet recruiting	Pericarditis, Tako-TSUBO Cardiomyopathy, Myocarditis, Inflammatory Cardiomyopathies, Lupus, Systemic Sclerosis...	300		clinicaltrials.gov
July 29, 2026	NCT07734012	Mycophenolate After Stem Cell Transplant for Systemic Sclerosis	Ottawa Hospital Research Institute	Phase 2	Not yet recruiting	Systemic Sclerosis (SSc)	6	Canada	clinicaltrials.gov
July 28, 2026	NCT07732309	A Study of ATG-201 in Adult Participants With Autoimmune Diseases	Antengene Biologics Limited	Phase 1	Recruiting	Systemic Lupus Erythematosus, Systemic Sclerosis (SSc), Sjogren's Disease, Autoimmune Diseases	149	China	clinicaltrials.gov
July 28, 2026	NCT07729995	BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease	Luminary Therapeutics	Phase 1	Not yet recruiting	Rheumatoid Arthritis (RA), Systemic Lupus Erthematosus (SLE), Dermatomyositis (DM), Systemic Sclerosis (SSc)	94	United States	clinicaltrials.gov
July 23, 2026	NCT07723872	Finger Versus Earlobe Pulse Oximetry During the 6-Minute Walk Test in Interstitial Lung Disease	Hospital de Granollers	Observational	Recruiting	Interstitial Lung Disease (ILD), Idiopathic Pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis, Connective Tissue...	100	Spain	clinicaltrials.gov
July 21, 2026	NCT07717060	Extracellular Vesicle Dynamics Predicting Vascular Complications and Treatment Response in Systemic Sclerosis	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	Not applicable	Not yet recruiting	Systemic Sclerosis, Pulmonary Arterial Hypertension, Digital Ulcers, Vascular Complications	60		clinicaltrials.gov
July 13, 2026	NCT07697274	Hyaluronidase for Sclerodactyly in Systemic Sclerosis Trial	Medical University of South Carolina	Early phase 1	Not yet recruiting	Systemic Sclerosis, Sclerodactyly	10	United States	clinicaltrials.gov
June 30, 2026	NCT07676266	A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy	The Affiliated Hospital of Qingdao University	Phase 1	Not yet recruiting	Multiple Sclerosis (MS), Myasthenia Gravis (MG), Neuromyelitis Optica Spectrum Disorder, Systemic Lupus Erythematosus...	18	China	clinicaltrials.gov
June 22, 2026	NCT07661836	Personalized Online Occupational Therapy Intervention for Adults With Scleroderma	Universidad de Zaragoza	Not applicable	Completed	Scleroderma, Scleroderma (Limited and Diffuse), Systemic Sclerosis (SSc)	24	Spain	clinicaltrials.gov
June 16, 2026	NCT07650565	Tissue Modeling in Systemic Sclerosis Using Induced Pluripotent Stem Cells (iPSCs)	University Hospital, Montpellier	Not applicable	Recruiting	Systemic Sclerosis (SSc)	16	France	clinicaltrials.gov
June 16, 2026	NCT07649265	A Trial in Healthy Adult Participants and Adults With Autoimmune Diseases to Test How HBM7020 is Tolerated and How it Behaves in the Body	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 1	Recruiting	Rheumatoid Arthritis, Systemic Lupus Erythematosus, Systemic Sclerosis, Sjögren's Disease	63	Australia	clinicaltrials.gov
June 11, 2026	NCT07642297	TL1A Inhibition in Systemic Sclerosis-Related Skin Fibrosis and Immunological Alterations: A Proof-of-Concept In Vitro Study (FIBROSTOP)	Fondazione Policlinico Universitario Campus Bio-Medico	Observational	Not yet recruiting	Systemic Sclerosis (SSc), Diffuse Cutaneous Systemic Sclerosis, Skin Fibrosis	20	Italy	clinicaltrials.gov
June 11, 2026	NCT07641634	A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis.	Prolium Bioscience, Inc	Phase 1/2	Recruiting	Healthy Volunteers, Systemic Sclerosis (SSc), Scleroderma, Systemic, Scleroderma	44	Australia, China, Mexico, South Korea	clinicaltrials.gov
May 19, 2026	NCT07596680	CD19/BCMA-Targeted Universal CAR-T Cell Injection for the Treatment of Autoimmune Diseases	Nanjing Bioheng Biotech Co., Ltd.	Early phase 1	Not yet recruiting	SLE - Systemic Lupus Erythematosus, Systemic Sclerosis, ANCA Associated Vasculitis, Idiopathic Inflammatory Myopathies...	30	China	clinicaltrials.gov
May 14, 2026	NCT07586267	CD19/BCMA UCAR-T for B Cell-Related Autoimmune Disease	The Children's Hospital of Zhejiang University School of Medicine	Early phase 1	Recruiting	Autoimmune Diseases, Systemic Lupus Erthematosus (SLE), Multi-Drug Resistant Nephrotic Syndrome, IgA Nephropathy...	15	China	clinicaltrials.gov
April 30, 2026	NCT07558850	Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune Diseases	The First Affiliated Hospital with Nanjing Medical University	Not applicable	Recruiting	Rheumatoid Arthritis, Dermatomyositis, Systemic Lupus Erythematosus, Systemic Sclerosis	72	China	clinicaltrials.gov
April 22, 2026	NCT07544225	Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic...	Gustave Roussy, Cancer Campus, Grand Paris	Phase 1	Not yet recruiting	Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE), Sjogren's Disease With Dry Eyes, Systemic Sclerosis...	6	France	clinicaltrials.gov
April 22, 2026	NCT07543679	Objective Assessment of Skin Damage Using ADHELASKIN in Patients With Systemic Sclerosis	Centre Hospitalier Universitaire de Saint Etienne	Not applicable	Recruiting	D013493	100	France	clinicaltrials.gov
April 21, 2026	NCT07542067	Infusion of Allogeneic Stromal Mesenchymal Stem Cells From Wharton´s Jelly in Patients With Diffuse Cutaneous Systemic Sclerosis With...	Fundación Neumologica Colombiana	Phase 1/2	Completed	Systemic Sclerosis Pulmonary, Pulmonary Hypertension, Pulmonary Fibrosis	1	Colombia	clinicaltrials.gov
April 17, 2026	NCT07535931	Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in the Treatment of Systemic Sclerosis	Shenzhen Huishan Biotechnology Co., Ltd.	Phase 1/2	Not yet recruiting	Systemic Sclerosis (SSc)	21		clinicaltrials.gov
April 14, 2026	NCT07527936	A Study of BEN301 Injection in theTreatment of Autoimmune Diseases	RenJi Hospital	Early phase 1	Suspended	Systemic Sclerosis (SSc), Rheumatoid Arthritis (RA), Sjogren's Syndrome (SS), Idiopathic Inflammatory Myopathies(IIM)	24	China	clinicaltrials.gov
April 13, 2026	NCT07526350	MTS109 in Patients With Refractory Autoimmune Diseases	Shanghai Changzheng Hospital	Early phase 1	Recruiting	Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies, Systemic Sclerosis (SSc), ANCA-Associated Vasculitis...	15	China	clinicaltrials.gov
April 13, 2026	NCT07523282	Safety and Preliminary Efficacy of HN2302 in Patients With Autoimmune Diseases	Shenzhen MagicRNA Biotechnology Co., Ltd	Phase 1	Not yet recruiting	Autoimmune Disease, Systemic Lupus Erythematosus, Systemic Sclerosis (SSc)	12	China	clinicaltrials.gov
April 7, 2026	NCT07515638	Immun4Cure Cohort of Autoimmune Diseases	University Hospital, Montpellier	Observational	Recruiting	Rheumatoid Arthritis, Systemic Lupus Erythematosus, Systemic Sclerosis, Healthy Adult Volunteers	500	France	clinicaltrials.gov
April 2, 2026	NCT07507201	Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease	The Children's Hospital of Zhejiang University School of Medicine	Early phase 1	Recruiting	Autoimmune Diseases, Systemic Lupus Erthematosus (SLE), Multi-Drug Resistant Nephrotic Syndrome, IgA Nephropathy...	15	China	clinicaltrials.gov
March 30, 2026	NCT07502105	Efficacy and Safety of Firsekibart in the Treatment of Systemic Sclerosis	Tongji Hospital	Not applicable	Not yet recruiting	Systemic Scleroderma	30	China	clinicaltrials.gov
March 27, 2026	NCT07497087	A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis	Boehringer Ingelheim	Phase 3	Recruiting	Systemic Sclerosis	448	Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, China...	clinicaltrials.gov
March 25, 2026	NCT07493395	Phase IIa Trial of Anti-CD19 CAR T-Cells in Systemic Sclerosis Resistant to Immunosuppressive Therapy	University Hospital, Montpellier	Phase 2	Recruiting	Scleroderma, Systemic	6	France	clinicaltrials.gov
March 16, 2026	NCT07473154	Controlling Hyperactive Immunity With Long-lived Lymphocytes	Quell Therapeutics Limited	Phase 1/2	Recruiting	Diffuse Cutaneous Systemic Sclerosis, Rheumatoid Arthritis (RA), Systemic Sclerosis (SSc), Autoimmune Rheumatologic...	16	Germany, Spain, United Kingdom	clinicaltrials.gov
March 16, 2026	NCT07472166	Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate	Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh	Phase 4	Completed	Scleroderma, Systemic	34	Bangladesh	clinicaltrials.gov
March 13, 2026	NCT07469865	Efficacy and Safety of 20% and 100% Autologous Serum Eye Drops in Patients With Severe Dry Eye Disease (AST)	University Hospital, Ghent	Not applicable	Completed	Dry Eye Disease	46	Belgium	clinicaltrials.gov
February 17, 2026	NCT07413341	A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases	Therorna	Phase 1	Recruiting	Systemic Lupus Erythematosus (SLE), Sjogren's Syndrome (SS), Systemic Sclerosis (SSc), Inflammatory Myopathy, ANCA...	12	China	clinicaltrials.gov
February 11, 2026	NCT07403188	A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101	Kyverna Therapeutics	Observational	Recruiting	Refractory Lupus Nephritis, Myasthaenia Gravis, Stiff Person Syndrome, Rheumatoid Arthritis (RA), Multiple Sclerosis...	70	United States	clinicaltrials.gov
February 11, 2026	NCT07402863	Self-Guided Resilience-Building Energy Management to Enhance Well-being (RENEW) Intervention for People With Systemic Sclerosis (SSc)	University of Michigan	Not applicable	Completed	Systemic Sclerosis	43	United States	clinicaltrials.gov
February 11, 2026	NCT07402226	Systemic Sclerosis DIet for GastrointESTinal Symptoms	University of Michigan	Not applicable	Recruiting	Systemic Sclerosis (SSc)	60	United States	clinicaltrials.gov
February 6, 2026	NCT07393217	Correlation Between Circulating Fibroblast Activation Protein (FAP) and Fibrosis in Two Diseases (Rheumatoid Arthritis and Systemic...	Sohag University	Observational	Not yet recruiting	Rheumatoid Arthritis (RA), Systemic Sclerosis (SSc)	111	Egypt	clinicaltrials.gov
January 22, 2026	NCT07361094	Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases	Beijing Boren Hospital	Phase 1	Withdrawn	Relapsed/Refractory Systemic Lupus Erythematosus, Relapsed/Refractory Systemic Sclerosis, Relapsed/Refractory...	0	China	clinicaltrials.gov
January 22, 2026	NCT07360808	Safety and Efficacy of Adipose-Derived Regenerative Cells (ADRCs) for Improving Hand Dysfunction in Systemic Sclerosis	Cytori Therapeutics	Not applicable	Recruiting	Systemic Sclerosis (SSc), Hand Dysfunction	48	China	clinicaltrials.gov
January 15, 2026	NCT07345052	Western Sweden Systemic Sclerosis Project	Sahlgrenska University Hospital	Observational	Recruiting	Scleroderma, Systemic, Fibrosis; Skin, Fibrosis Lung, Interstitial Lung Disease Due to Systemic Disease	150	Sweden	clinicaltrials.gov
January 15, 2026	NCT07343115	Familial Systemic Scleroderma	University Hospital, Strasbourg, France	Observational	Recruiting	Systemic Scleroderma	20	France	clinicaltrials.gov
January 14, 2026	NCT07339540	the Safety and Efficacy of Targeted BCMA In Vivo LV Injection for Recurrent or Refractory Autoimmune Diseases	Tongji Hospital	Early phase 1	Active not recruiting	Recurrent or Refractory Systemic Lupus Erythematosus, Recurrent or Refractory IgG4 Related Diseases, Recurrent or...	45	China	clinicaltrials.gov
January 13, 2026	NCT07335562	A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care...	Juno Therapeutics, Inc., a Bristol-Myers Squibb Company	Phase 3	Not yet recruiting	Systemic Sclerosis	92	Belgium, Canada, France, Germany, Italy, Japan, Spain, Switzerland, United...	clinicaltrials.gov
January 8, 2026	NCT07326033	Efficacy and Safety of Allogenic Cultured Adipose-derived Mesenchymal Stromal Cell Injections on MoUth Fibrosis and Handicap in Patients...	University Hospital, Toulouse	Phase 2	Not yet recruiting	Systemic Scleroderma	50	France	clinicaltrials.gov
December 26, 2025	NCT07305116	CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease	The Children's Hospital of Zhejiang University School of Medicine	Phase 1	Recruiting	Autoimmune Diseases, Systemic Lupus Erthematosus (SLE), Multi-Drug Resistant Nephrotic Syndrome, IgA Nephropathy...	15	China	clinicaltrials.gov
December 24, 2025	NCT07301164	Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases	Peking University Third Hospital	Early phase 1	Recruiting	System Lupus Erythematosus, Systemic Sclerosis (SSc), Inflammatory Myositis, Antiphospholipid Syndrome, ANCA Associated...	10	China	clinicaltrials.gov
December 22, 2025	NCT07295847	A Study of AZD0120 in Autoimmune Diseases	AstraZeneca	Phase 1/2	Recruiting	Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Rheumatoid Arthritis	27	Australia, Germany, Spain, Sweden, United Kingdom, United States	clinicaltrials.gov
December 18, 2025	NCT07292961	Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With Scleroderma	Hacettepe University	Not applicable	Recruiting	Scleroderma, Scleroderma, Localized, Scleroderma Systemic, Scleroderma (Limited and Diffuse), Systemic Sclerosis (SSc)...	48	Turkey (Türkiye)	clinicaltrials.gov
December 16, 2025	NCT07284797	A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases	Xencor, Inc.	Phase 1	Recruiting	Healthy, Idiopathic Inflammatory Myopathies, Systemic Sclerosis, Sjögren's Disease	60	Australia	clinicaltrials.gov
December 11, 2025	NCT07277491	Assessment of Nutritional Status in Rheumatic Diseases and Association to Disease Activity	Cairo University	Observational	Completed	Spondyloarthritis (SpA), Psoriatic Arthritis (PsA), Systemic Lupus Erythematous (SLE), Systemic Sclerosis (SSc)...	460	Egypt	clinicaltrials.gov
November 26, 2025	NCT07251179	Characterization of Autoreactive b Lymphocytes in Autoimmune Diseases and Immune Deficiencies	University Hospital, Strasbourg, France	Observational	Recruiting	Systemic Lupus Erythematosus, Systemic Scleroderma, ANCA-associated Vasculitis, Antiphospholipid Syndrome, Primary...	200	France	clinicaltrials.gov
November 25, 2025	NCT07249060	Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimmune Disease Patients	Hospital Universitario Araba	Observational	Recruiting	Immune-Related Adverse Events, Lupus Erythematosus, Systemic, Sjogren Syndrome, Systemic Sclerosis (SSc), Inflammatory...	300	Spain	clinicaltrials.gov
November 24, 2025	NCT07246096	Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory...	Changhai Hospital	Early phase 1	Recruiting	Autoimmune Diseases, Systemic Lupus Erythematosus, Systemic Sclerosis, Primary Sjögren Syndrome, Rheumatoid Arthritis...	60	China	clinicaltrials.gov
November 24, 2025	NCT07245238	Topical Cannabidiol Lotion for Pruritus Relief in Scleroderma	Khon Kaen University	Phase 3	Recruiting	Mediciine, Systemic Sclerosis (SSc), Intervention Study	36	Thailand	clinicaltrials.gov
November 19, 2025	NCT07236970	Multicenter Study on the Development of Pulmonary Arterial Hypertension Screening Models Based on Artificial Intelligence for Patients With...	Alejandro Cruz Utrilla	Observational	Recruiting	Pulmonary Hypertension, Systemic Sclerosis (SSc), Systemic Sclerosis-Associated PAH	350	Spain	clinicaltrials.gov
November 19, 2025	NCT07236801	Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune Diseases	China Immunotech (Beijing) Biotechnology Co., Ltd.	Phase 1	Recruiting	Systemic Lupus Erythematosus (SLE), Systemic Sclerosis, Sjogren's Syndrome (SS), Inflammatory Myopathy, Anti-Neutrophil...	18	China	clinicaltrials.gov
November 14, 2025	NCT07228429	Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images	Yale University	Observational	Recruiting	Systemic Sclerosis (SSc), Calcinosis Cutis	56	United States	clinicaltrials.gov
October 8, 2025	NCT07212959	As Part of a Pilot Study, Visualization of Inflammatory Activity in Systemic Sclerosis Using CXCR4 PET/CT	Wuerzburg University Hospital	Not applicable	Completed	Systemic Sclerosis (SSc)	12	Germany	clinicaltrials.gov
October 8, 2025	NCT07212322	A Study of CD19 UCAR-T Cells in Subjects With Autoimmune Diseases	Institute of Hematology & Blood Diseases Hospital, China	Not applicable	Not yet recruiting	Systemic Lupus Erythematosus, Idiopahic Inflammatory Myopathies, Anti-Neutrophil Cytoplasmic Antibody-Associated...	24	China	clinicaltrials.gov
October 7, 2025	NCT07209644	Catestatin as a Novel Biomarker for Cardiovascular and Microvascular Involvement in Systemic Sclerosis	Assiut University	Observational	Not yet recruiting	Systemic Sclerosis	70		clinicaltrials.gov
September 23, 2025	NCT07188285	Mass Spectrometry-based Immune Profiling in Autoimmune Diseases	Peking University People's Hospital	Observational	Enrolling by invitation	Systemic Lupus Erthematosus, Sjogren's Syndrome, Inflammatory Myopathies, Systemic Sclerosis (SSc), Vasculitis...	500	China	clinicaltrials.gov
September 19, 2025	NCT07184450	Clinical Study of BCMA/CD70-targeted CAR-T Therapy for Refractory Pediatric Rheumatic Diseases	Chongqing Precision Biotech Co., Ltd	Phase 1	Recruiting	Juvenile Dermatomyositis (JDM), Polyarticular Juvenile Idiopathic Arthritis, Systemic Sclerosis (SSc), Primary...	11	China	clinicaltrials.gov
September 19, 2025	NCT07183072	Patients Diagnosed With Scleroderma: Physical Performance and Functionality	Hacettepe University	Observational	Recruiting	Systemic Sclerosis (SSc), Scleroderma, Scleroderma (Limited and Diffuse), Scleroderma, Localized, Functionality	50	Turkey (Türkiye)	clinicaltrials.gov
September 19, 2025	NCT07182981	Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance	Hacettepe University	Observational	Recruiting	Systemic Sclerosis (SSc), Scleroderma, Scleroderma (Limited and Diffuse), Scleroderma, Localized, Swallowing	50	Turkey (Türkiye)	clinicaltrials.gov
September 19, 2025	NCT07182968	Cultural Adaptation, Validity, and Reliability of the Turkish Version of The PASTUL Questionnaire	Hacettepe University	Observational	Recruiting	Systemic Sclerosis (SSc), Systemic Sclerosis (Scleroderma), Scleroderma (Limited and Diffuse), Patient Perspective	50	Turkey (Türkiye)	clinicaltrials.gov
September 16, 2025	NCT07175246	Exploring the Patterns of Sleep Disordered Breathing in Systemic Sclerosis Patients	Assiut University	Observational	Not yet recruiting	Systemic Sclerosis, Sleep-Disordered Breathing	30	Egypt	clinicaltrials.gov
September 11, 2025	NCT07167537	A Study of OL-CD19-GDT in Relapsed/ Refractory Autoimmune Diseases	Beijing GoBroad Hospital	Phase 1	Recruiting	Systemic Sclerosis (SSc), Primary Sjogren's Syndrome	44	China	clinicaltrials.gov
September 8, 2025	NCT07159009	A Study of GB261 in Systemic Sclerosis	Ruijin Hospital	Early phase 1	Not yet recruiting	Systemic Sclerosis (SSc)	10		clinicaltrials.gov
September 8, 2025	NCT07158996	A Study of Cizutamig in Systemic Sclerosis	Ruijin Hospital	Early phase 1	Not yet recruiting	Systemic Sclerosis (SSc)	10		clinicaltrials.gov
September 4, 2025	NCT07155369	UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases	The Affiliated Hospital of Xuzhou Medical University	Not applicable	Active not recruiting	Systemic Lupus Erythematosus, Systemic Sclerosis	18	China	clinicaltrials.gov
September 2, 2025	NCT07150000	Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy	University of Bonn	Observational	Recruiting	Rheumatic Diseases, Rheumatoid Arthritis (RA), Giant Cell Arteritis (GCA), Psoriatic Arthritis (PsA), Axial...	120	Germany	clinicaltrials.gov
August 13, 2025	NCT07121777	Anti CD19/BCMA CAR Gene Therapy for Autoimmune Diseases	Anhui Provincial Hospital	Not applicable	Recruiting	Autoimmune Diseases	18	China	clinicaltrials.gov
August 11, 2025	NCT07115745	A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases	Juno Therapeutics, Inc., a Bristol-Myers Squibb Company	Phase 1	Recruiting	Refractory Autoimmune Diseases	125	Australia, Brazil, Czechia, France, Germany, Israel, Poland, Romania, Spain...	clinicaltrials.gov
August 8, 2025	NCT07112183	Open Label Treprostinil Raynaud's Study	Brigham and Women's Hospital	Phase 4	Recruiting	Raynaud's Disease, Raynaud Phenomena, Raynauds	30	United States	clinicaltrials.gov
August 5, 2025	NCT07104721	A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases	China Immunotech (Beijing) Biotechnology Co., Ltd.	Phase 1	Recruiting	Systemic Lupus Erythematosus (SLE), Lupus Nephritis (LN), Systemic Sclerosis (SSc), Inflammatory Myopathy...	18	China	clinicaltrials.gov
July 29, 2025	NCT07090226	Diffuse Cutaneous Scleroderma (DSSc) SFDI Study	Boston University	Not applicable	Recruiting	Systemic Scleroderma, Diffuse Cutaneous Scleroderma	65	United States	clinicaltrials.gov
July 28, 2025	NCT07087912	Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases	University of Sao Paulo General Hospital	Phase 4	Recruiting	Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA), Systemic Lupus Erythematosus (SLE), Juvenile Systemic...	477	Brazil	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Assistance Publique - Hôpitaux de Paris	7	November 9, 2026
Beijing GoBroad Hospital	5	September 11, 2025
Assiut University	4	September 24, 2026
Peking University Third Hospital	4	September 23, 2026
The Children's Hospital of Zhejiang University School of Medicine	4	May 14, 2026
Hacettepe University	4	December 18, 2025
Khon Kaen University	3	August 12, 2026
University Hospital, Montpellier	3	June 16, 2026
University of Michigan	3	February 11, 2026
China Immunotech (Beijing) Biotechnology Co., Ltd.	3	November 19, 2025
Istanbul University - Cerrahpasa	2	October 5, 2026
Nanjing Bioheng Biotech Co., Ltd.	2	May 19, 2026
Tongji Hospital	2	March 30, 2026
University Hospital, Strasbourg, France	2	January 15, 2026
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company	2	January 13, 2026
Institute of Hematology & Blood Diseases Hospital, China	2	October 8, 2025
Peking University People's Hospital	2	September 23, 2025
Ruijin Hospital	2	September 8, 2025
Anhui Provincial Hospital	2	August 13, 2025
PersonGen BioTherapeutics (Suzhou) Co., Ltd.	2	May 21, 2025

By phase

Phase	New trials	Latest
Phase 1	30	October 30, 2026
Not applicable	29	November 9, 2026
Observational	29	October 22, 2026
Early phase 1	19	September 8, 2026
Phase 2	17	November 9, 2026
Phase 1/2	15	September 2, 2026
Phase 3	4	August 12, 2026
Phase 4	3	March 16, 2026

By country

Country	New trials	Latest
China	47	September 23, 2026
United States	27	November 9, 2026
France	20	November 9, 2026
Spain	12	July 23, 2026
Germany	10	October 14, 2026
Australia	8	August 21, 2026
Turkey (Türkiye)	7	October 5, 2026
Canada	6	July 29, 2026
United Kingdom	6	March 27, 2026
Belgium	5	October 14, 2026
Poland	5	October 14, 2026
Italy	4	June 11, 2026
Brazil	4	March 27, 2026
Romania	4	March 27, 2026
Switzerland	4	March 27, 2026
Egypt	4	February 6, 2026
Mexico	3	June 11, 2026
South Korea	3	June 11, 2026
Israel	3	March 27, 2026
Norway	3	March 27, 2026
Sweden	3	March 27, 2026
Thailand	3	March 27, 2026
Netherlands	2	October 14, 2026
Denmark	2	September 25, 2026
Colombia	2	April 21, 2026

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.