Data / New clinical trials / Periodontal Diseases

Periodontal Diseases trials: 255 new since Nov 2024

Name: New Periodontal Diseases clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Periodontal Diseases clinical trials: 255 rows for $12.75, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 10 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/periodontal-diseases, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 9, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

255 clinical studies in Periodontal Diseases were first posted on ClinicalTrials.gov from November 18, 2024 to November 9, 2026; 8 have an industry sponsor and 102 are recruiting or about to. The newest, NCT07924423, was posted on November 9, 2026: The Effect of Using Plaque-disclosing Tablets on the Effectiveness of Toothbrushing and Gingival Health in... (Ezgi Sila Taskaldiran).

The request: Every new Periodontal Diseases clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

255New trials
8Industry sponsored
102Recruiting or not yet
November 9, 2026Latest posted

Newest trials

The newest 100 of 255, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 9, 2026	NCT07924423	The Effect of Using Plaque-disclosing Tablets on the Effectiveness of Toothbrushing and Gingival Health in Children	Ezgi Sila Taskaldiran	Not applicable	Completed	Gingivitis and Periodontal Diseases	53	Turkey (Türkiye)	clinicaltrials.gov
November 3, 2026	NCT07914400	Timing of Oral Hygiene Improvement Relative to Subgingival Instrumentation	University of Ljubljana	Not applicable	Completed	Periodontal Diseases Inflammation, Periodontal Disease, Periodontal Attachment Loss, Periodontal Pocket, Oral Hygiene...	10	Slovenia	clinicaltrials.gov
October 30, 2026	NCT07905859	Effects Of Periodontal Therapy In Patients With Inflammatory Bowel Disease	University of Turin, Italy	Observational	Recruiting	Periodontal Diseases, IBD, Dysbiosis, Inflammation	30	Italy	clinicaltrials.gov
October 23, 2026	NCT07892638	NON-SURGİCAL PERİODONTAL THERAPY WİTH L-ARGİNİNE	Alanya Alaaddin Keykubat University	Not applicable	Active not recruiting	Periodontal Disease, Periodontal Diseases	60	Turkey (Türkiye)	clinicaltrials.gov
October 21, 2026	NCT07887204	Antibiotic Resistance Genes in Periodontitis	Istanbul University	Observational	Active not recruiting	Periodontal Disease, Periodontitis, Antibiotic Resistance Genes	50	Turkey (Türkiye)	clinicaltrials.gov
October 20, 2026	NCT07882394	Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in Gingivitis	Biruni University	Not applicable	Recruiting	Gingivitis and Periodontal Diseases	80	Turkey (Türkiye)	clinicaltrials.gov
October 19, 2026	NCT07880808	Prevalence of Caries and Periodontal Disease and Their Correlation in a Dental School in Egypt	Cairo University	Observational	Completed	Periodontal Diseases, Dental Caries	369	Egypt	clinicaltrials.gov
October 19, 2026	NCT07880717	Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years	Mahidol University	Observational	Recruiting	Diabete Mellitus, Dyslipidaemia, Chronic Kidney Disease, Psychiatric Disorder, Hypertension, Hypothyroidism, Smoking...	93	Thailand	clinicaltrials.gov
October 19, 2026	NCT07880483	Comparision of Enzymatic and Active Salt Toothpaste	Uttar Pradesh University of medical sciences	Not applicable	Completed	Gingivitis; Chronic, Gingivitis and Periodontal Diseases, Dental Plaque	93	India	clinicaltrials.gov
October 14, 2026	NCT07873385	Evaluation of MTHFR Gene Polymorphism and Periodontal Clinical Parameters in Healthy, Hypertensive, and Periodontitis Individuals	Akdeniz University	Observational	Completed	Hypertension, Periodontitis	200	Turkey (Türkiye)	clinicaltrials.gov
October 6, 2026	NCT07861880	Comparative Evaluation of Oxygen-enriched and Chlorohexidine Mouthwashes as an Adjunct to Non-surgical Periodontal Therapy and Its Efficacy...	Cairo University	Phase 3	Completed	Periodontal Disease, Periodontal Diseases Inflammation, Gingivitis, Mouthwash	72	Egypt	clinicaltrials.gov
October 5, 2026	NCT07856901	Retinal and Choroidal Changes in Periodontal Disease	Zeliha Başak Çakır Erdil	Observational	Not yet recruiting	Periodontal Diseases, Periodontal Diseases Inflammation, Retinal Thickening	80	Turkey (Türkiye)	clinicaltrials.gov
September 24, 2026	NCT07840131	Anti-microbial Effect of Acacia Arabica Extract on Gingival and Periodontal Health of Dental Patients	Umm Al-Qura University	Not applicable	Completed	Gingival and Periodontal Disease	30	Saudi Arabia	clinicaltrials.gov
September 17, 2026	NCT07824518	Comparison of Autologous Tooth and Bovine Xenograft in Periodontal Healing After Mandibular Third Molar Extraction	Universidad Complutense de Madrid	Not applicable	Recruiting	Periodontal Defects After Third Molar Extraction, Periodontal Disease	30	Spain	clinicaltrials.gov
September 16, 2026	NCT07822269	Dental Loupe Versus Dental Operating Microscope for Non-Surgical Periodontal Treatment	Saglik Bilimleri Universitesi	Not applicable	Recruiting	Periodontitis, Periodontitis and Treatment Need, Periodontal Disease, Periodontal Pocket, Periodontitis (Stage 3)	30	Turkey (Türkiye)	clinicaltrials.gov
September 10, 2026	NCT07813936	Locally Delivered Melatonin Gel in Management of Stage II Grade B Periodontitis	Alexandria University	Not applicable	Not yet recruiting	Periodontal Diseases	23	Egypt	clinicaltrials.gov
September 9, 2026	NCT07809477	Integrated Diabetes and Oral Health Care in Oman	Oman Ministry of Health	Not applicable	Not yet recruiting	Type 2 Diabetes Mellitus, Periodontitis, T2DM, Periodontal Disease, Type 2 Diabetes, Gum Inflammation, Non Insulin...	290		clinicaltrials.gov
September 8, 2026	NCT07807397	Oral Hygiene Assistance Training Program	Colgate Palmolive	Phase 4	Not yet recruiting	Elderly, Periodontal Disease, Gingivitis, Caries,Dental	500		clinicaltrials.gov
September 8, 2026	NCT07807215	Laser Assisted Open Flap Debridement	University of Bari Aldo Moro	Not applicable	Not yet recruiting	Periodontal Disease, Periodontal Bone Loss	20	Italy	clinicaltrials.gov
September 3, 2026	NCT07803484	Efficacy of Oral Hygiene Regimens in Patients Undergoing Non-Surgical Periodontal Treatment	Colgate Palmolive	Phase 3	Not yet recruiting	Periodontal Disease, Gingival Inflammation and Bleeding	100	Brazil	clinicaltrials.gov
September 3, 2026	NCT07802249	Periodontal Health in Adults Treated With Fixed Orthodontic Appliances or Clear Aligners	Ravan Mammadov	Observational	Active not recruiting	Malocclusion, Periodontal Diseases, Periodontal Health	30	Turkey (Türkiye)	clinicaltrials.gov
September 1, 2026	NCT07798765	Comparative Evaluation of Effect of NSPT With & Without Adjunctive LANAP on OHRQoL: A Randomized Clinical Trial.	Mahe Nigar	Not applicable	Completed	Periodontal Diseases	120	India	clinicaltrials.gov
August 28, 2026	NCT07793370	Evaluation of PTHrP, RANKL, and OPG Levels in Periodontal Health and Diseases	Abant Izzet Baysal University	Observational	Completed	Periodontitis, Gingivitis, Periodontal Disease	81	Turkey (Türkiye)	clinicaltrials.gov
August 28, 2026	NCT07792902	Microbiological Modulation Of The Oral-Gut Axis After Treatment With Or Without Systemic Use Of Probiotics In Patients With Periodontitis...	University of Sao Paulo	Phase 1	Completed	Periodontitis Stage IV, Periodontitis	40	Brazil	clinicaltrials.gov
August 28, 2026	NCT07791927	Effect of Non-Surgical Periodontal Therapy on Inflammation in Heart Transplant Recipients	Baskent University	Not applicable	Completed	Heart Transplant, Periodontitis, Gingivitis, Systemic Inflammation	20		clinicaltrials.gov
August 27, 2026	NCT07791238	Minimally Invasive Non-Surgical Periodontal Therapy Alone vs. Minimally Invasive Non-Surgical Periodontal Therapy With I-PRF With or...	Cairo University	Phase 1/2	Not yet recruiting	Bony Defects, Periodontal Disease	63		clinicaltrials.gov
August 26, 2026	NCT07787676	Periodontal Status and Thyroid Markers in Pregnancy	Postgraduate Institute of Dental Sciences Rohtak	Observational	Not yet recruiting	Pregnancy, Thyroid Disease Pregnancy, Periodontal Disease	100	India	clinicaltrials.gov
August 18, 2026	NCT07770906	Effect of GLP-1 Receptor Agonists on Periodontal Health and Response to Nonsurgical Periodontal Therapy	Cukurova University	Not applicable	Not yet recruiting	Periodontal Disease, Obesity & Overweight	40		clinicaltrials.gov
August 17, 2026	NCT07769112	Comparative Efficacy of Oil Pulling and Chlorhexidine on Plaque Induced Gingivitis	Liaquat College of Medicine and Dentistry	Not applicable	Completed	Plaque Induced Gingivitis	80	Pakistan	clinicaltrials.gov
August 12, 2026	NCT07760935	Digital vs Conventional VFR in Post-Orthodontic Retention	Ziauddin University	Not applicable	Not yet recruiting	Periodontal Disease; Gingivitis; Dental Plaque; Malocclusion (Post-orthodontic Treatment)	52		clinicaltrials.gov
August 12, 2026	NCT07759466	Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease	Inonu University	Observational	Completed	Periodontal Disease, Gingivitis and Periodontal Diseases, Biomarker Discovery and Validation, Pathways	75	Turkey (Türkiye)	clinicaltrials.gov
August 4, 2026	NCT07745803	Discovery and Validation of Biomarkers for Periodontitis, Dental Caries and Oral Squamous Cell Carcinoma	Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University	Observational	Not yet recruiting	Oral Squamous Cell Carcinoma (OSCC), Periodontal Disease, Dental Caries	4,000	China	clinicaltrials.gov
July 30, 2026	NCT07737678	Evaluation of NIPSA Using Alloplastic Bone Graft and Cross-Linked Hyaluronic Acid in theTreatment of Intrabony Defects	Mansoura University	Phase 1/2	Not yet recruiting	Intrabony Periodontal Defect, Periodontal Disease	60		clinicaltrials.gov
July 28, 2026	NCT07731113	Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III...	Cairo University	Not applicable	Active not recruiting	Periodontology, Periodontal Disease, Periodontal Diseases, Periodontitis (Stage 3), Gingivitis and Periodontal...	72	Egypt	clinicaltrials.gov
July 24, 2026	NCT07725913	Thermosensitive Hyaluronic Gel With Octenidine as an Adjunctive to Subgingival Instrumentation	University of Bologna	Not applicable	Recruiting	Periodontal Disease	40	Italy	clinicaltrials.gov
July 24, 2026	NCT07725276	Comparing the Efficacy of Toothbrushing With and Without Interproximal Cleaning Aids: A Split-Mouth Trial	Saint-Joseph University	Not applicable	Completed	Gingivitis, Dental Plaque, Periodontal Disease	29	Lebanon	clinicaltrials.gov
July 23, 2026	NCT07721428	Salivary Angiotensin-Converting Enzyme and Periodontal Disease in Cardiovascular Disease	Suleyman Demirel University	Observational	Completed	Periodontal Disease, Cardiovascular Disease	76	Turkey (Türkiye)	clinicaltrials.gov
July 21, 2026	NCT07718074	Probiotic Response in Periodontal Disease	University of New Hampshire	Not applicable	Not yet recruiting	Periodontal Disease	100		clinicaltrials.gov
July 21, 2026	NCT07718061	Bacterial Diversity Study Using 16S rRNA Sequencing of Periodontal Samples From Patients With Orthodontic Retainers	Universidad de Murcia	Not applicable	Recruiting	Fixed Orthodontic Retainer, Orthodontic Appliances, Removable, Orthodontic Appliance Complication, Gingivitis...	10	Spain	clinicaltrials.gov
July 17, 2026	NCT07711431	Association Between Periodontal Disease and Chronic Neck Pain	Nigde Omer Halisdemir University	Observational	Recruiting	Periodontal Disease, Chronic Neck Pain	123	Turkey (Türkiye)	clinicaltrials.gov
July 16, 2026	NCT07707063	This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in...	Military Hospital of Tunis	Phase 4	Recruiting	Periodontitis, Smokers, Non Smokers, Periodontal Disease	50	Tunisia	clinicaltrials.gov
July 15, 2026	NCT07706049	Video vs. Model-Based Oral Hygiene Instruction in Gingivitis Patients	Ankara University	Not applicable	Completed	Gingivitis and Periodontal Diseases, Gingivitis	80	Turkey (Türkiye)	clinicaltrials.gov
July 13, 2026	NCT07699978	Maternal Periodontal Inflammation and Pregnancy Outcomes: Salivary and Amniotic Biomarkers	Saglik Bilimleri Universitesi	Observational	Not yet recruiting	Periodontal Disease, Pregnancy, Preterm Birth	80		clinicaltrials.gov
July 13, 2026	NCT07697963	Evaluation of Photodynamic Therapy as an Adjunct to Non-surgical Treatment in Periodontitis in Smokers vs. Non-smokers	University of Pristina	Early phase 1	Completed	Periodontal Disease	120		clinicaltrials.gov
July 13, 2026	NCT07697209	Adjunctive Antioxidant Effect of Centella Asiatica Nanoemulsion Gel in Management of Periodontitis	Mansoura University	Not applicable	Completed	Periodontal Diseases, Periodontal Bone Loss	45	Egypt	clinicaltrials.gov
July 8, 2026	NCT07691437	Effect of Non-Surgical Periodontal Treatment on Oral Health in Hemophilia Patients	Karadeniz Technical University	Not applicable	Completed	Hemophilia A and B, Periodontitis, Hemophilia	146	Turkey (Türkiye)	clinicaltrials.gov
July 8, 2026	NCT07691060	Asprosin and Total Antioxidant/Oxidant Status in Diabetes and Periodontal Disease	Saglik Bilimleri Universitesi	Observational	Completed	Periodontal Diseases, Gingival Diseases, Type 2 Diabetes	67	Turkey (Türkiye)	clinicaltrials.gov
July 8, 2026	NCT07689786	Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis	Mustafa Kemal University	Observational	Not yet recruiting	Gingivitis; Chronic	36	Turkey (Türkiye)	clinicaltrials.gov
July 8, 2026	NCT07689552	Deep Learning-Based Measurement of Keratinized Gingiva Width Using Smartphone-Acquired Clinical Images	Al-Azhar University	Observational	Completed	Periodontal Diseases	50	Egypt	clinicaltrials.gov
July 8, 2026	NCT07689071	Bio-Descaling Toothpaste for Dental Calculus Reduction	Universidad Complutense de Madrid	Not applicable	Not yet recruiting	Dental Calculus, Gingivitis and Periodontal Diseases, Periodontal Diseases	100		clinicaltrials.gov
July 7, 2026	NCT07688421	Short Implants Produced by Additive Manufacturing in the Posterior Jaws: 3 Years of Follow-up	University of Guarulhos	Observational	Enrolling by invitation	Periodontal Diseases, Dental Implant Failed	100	Brazil	clinicaltrials.gov
July 7, 2026	NCT07688408	Short Implants in Unitary Implant-supported Rehabilitations in the Posterior Maxilla and Mandible: 5 Years of Follow-up	University of Guarulhos	Observational	Not yet recruiting	Periodontitis, Periodontal Disease	100	Brazil	clinicaltrials.gov
July 6, 2026	NCT07684001	Longitudinal Evaluation of Several Modalities of Treatment of Peri-implantitis: 5 to 23 Years Follow-up	University of Guarulhos	Observational	Not yet recruiting	Periodontal Disease, Microbiology	300		clinicaltrials.gov
July 1, 2026	NCT07678125	Influence of Re-evaluation Timing After Phase I Periodontal Therapy on Clinical and Periodontal Outcomes.	Gulf Medical University	Not applicable	Not yet recruiting	Periodontal Diseases, Periodontitis (Stage 3), Subgingival Debridement	24	United Arab Emirates	clinicaltrials.gov
June 30, 2026	NCT07674888	Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets	University of Alberta	Not applicable	Not yet recruiting	Dental Caries, Periodontitis, Oral Microbiome, Bacterial Transmission	225	Canada	clinicaltrials.gov
June 29, 2026	NCT07673185	Omega-3 Plus Low-Dose Aspirin in Smokers With Stage III Periodontitis	Al-Azhar University	Not applicable	Recruiting	Periodontal Disease, Periodontitis (Stage 3), Smoking Behaviors	40	Egypt	clinicaltrials.gov
June 26, 2026	NCT07672379	Effects of Adjunctive Synbiotic Supplementation to Non-Surgical Periodontal Therapy in Smokers With Periodontitis	Biruni University	Not applicable	Not yet recruiting	Periodontal Disease	92	Turkey (Türkiye)	clinicaltrials.gov
June 26, 2026	NCT07671274	Comparison of the Efficacy of Conventional Versus Minimally Invasive Non-Surgical Periodontal Therapy in Periodontitis Patients	Mansoura University	Early phase 1	Recruiting	Periodontal Disease, Stage III Periodontitis	30	Egypt	clinicaltrials.gov
June 25, 2026	NCT07669233	Salivary Free Amino Acid Profiles in Periodontitis: Associations With Clinical Parameters and Dynamic Responses to Non Surgical Therapy	Zhang, Yuwei	Not applicable	Completed	Periodontitis, Gingivitis and Periodontal Diseases, Periodontal Debridement, Periodontal Attachment Loss, Periodontal...	77	China	clinicaltrials.gov
June 24, 2026	NCT07666126	Evaluation of the Effect of Hyperuricemia on Alveolar Bone Loss	Recep Tayyip Erdogan University Training and Research Hospital	Observational	Recruiting	Periodontal Diseases, Hyperuricemia, Oxidative Stress	80	Turkey (Türkiye)	clinicaltrials.gov
June 22, 2026	NCT07661784	Salivary Biomarkers in Periodontal Disease Progression	Suleyman Demirel University	Observational	Recruiting	Periodontal Disease, Gingivitis and Periodontal Diseases, Periodontitis	240	Turkey (Türkiye)	clinicaltrials.gov
June 16, 2026	NCT07651579	Evaluation of the Impact of Periodontitis and Its Treatment on Swallowing Functions and Oral Quality of Life	University Hospital, Clermont-Ferrand	Not applicable	Recruiting	Periodontitis, Periodontal Diseases, Quality of Life	44	France	clinicaltrials.gov
June 15, 2026	NCT07647874	Assessment of Spirulina Gel Prepared By Different Extraction Methods as an Adjunctive Therapy to Mechanical Debridement in the Treatment of...	Mansoura University	Early phase 1	Completed	Periodontal Disease, Periodontitis Stage II, Periodontal Therapy	75	Egypt	clinicaltrials.gov
June 11, 2026	NCT07642037	Marginal Biofilm Distribution and Periodontal Response to Supragingival and Juxtagingival Aligner Designs	George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures	Not applicable	Completed	Periodontal Diseases, Dental Plaque, Gingivitis	20	Romania	clinicaltrials.gov
June 9, 2026	NCT07636993	Assessment of Ozonated Sunflower Seed Oil Gel as an Adjunctive Therapy to Mechanical Debridement in the Treatment of Stage II Grade B...	Mansoura University	Early phase 1	Completed	Periodontal Disease, Periodontitis, Periodontitis Stage II	60	Egypt	clinicaltrials.gov
June 9, 2026	NCT07636954	Touch-to-Teach Interdental Brush Instruction Versus Conventional Guidance on Gingival Health in Patients With Fixed Dental Prostheses	Gulf Medical University	Not applicable	Completed	Gingivitis, Periodontal Disease, Fixed Dental Prosthesis, Dental Plaque	32	United Arab Emirates	clinicaltrials.gov
June 9, 2026	NCT07636733	The Effect of Vitamin D Supplementation on the Anti-inflammatory Response in Periodontal Diseases	Recep Tayyip Erdogan University Training and Research Hospital	Not applicable	Recruiting	Periodontal Diseases, Gingivitis, Vitamin D Deficiency	120	Turkey (Türkiye)	clinicaltrials.gov
June 8, 2026	NCT07634250	Mental Health and Periodontitis in Probable Bruxers	Postgraduate Institute of Dental Sciences Rohtak	Observational	Not yet recruiting	Periodontal Disease	110	India	clinicaltrials.gov
June 8, 2026	NCT07633405	Photodynamic Therapy as an Adjunct in Periodontal Treatment	Universidad Catolica Santiago de Guayaquil	Not applicable	Enrolling by invitation	Periodontitis, Periodontal Disease	30	Ecuador	clinicaltrials.gov
June 5, 2026	NCT07629934	Artificial Intelligence for Diagnosing Periodontitis and Monitoring Gingival Inflammation	Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University	Observational	Active not recruiting	Periodontal Disease	900	China	clinicaltrials.gov
June 5, 2026	NCT07628803	Relationship Between Periodontal Inflammation Severity and Pan-Immune System Inflammation Value	Abant Izzet Baysal University	Observational	Completed	Periodontitis, Gingivitis, Periodontal Health	160	Turkey (Türkiye)	clinicaltrials.gov
June 4, 2026	NCT07626801	Effect of Preoperative Periodontal Treatment on Postoperative Infection and Mortality After Aortic and Mitral Valve Surgery	Istanbul University - Cerrahpasa	Observational	Completed	Periodontitis, Heart Valve Disease, Postoperative Infection, Cardiovascular Disease	200	Turkey (Türkiye)	clinicaltrials.gov
June 2, 2026	NCT07619729	Evaluate the Efficacy of an Oral Health Behavioral Intervention in People With Diabetes	Colgate Palmolive	Phase 4	Enrolling by invitation	Diabetes Type 2, Periodontal Disease, Caries	10,000	United States	clinicaltrials.gov
May 29, 2026	NCT07615361	Odontogenic Graft Obtained From Human Tooth and Low Level Laser Therapy	Istanbul Saglik Bilimleri University	Not applicable	Enrolling by invitation	Laser Therapy, Periodontal Diseases, Bone Loss in Jaw, Alveolar Bone Loss, Periodontal Bone Loss, Periodontal Atrophy	21	Turkey (Türkiye)	clinicaltrials.gov
May 26, 2026	NCT07605767	Adjunctive Topical Melatonin Gel in Non-Surgical Periodontal Therapy for Periodontitis	Liaquat College of Medicine and Dentistry	Phase 4	Completed	Periodontal Disease, Melatonin	30	Pakistan	clinicaltrials.gov
May 22, 2026	NCT07604493	Oral Health and Systemic Diseases: Survey of General Practitioners	University of Roma La Sapienza	Observational	Recruiting	Periodontal Disease, Diabete Mellitus	100	Italy	clinicaltrials.gov
May 22, 2026	NCT07602738	Evaluation of Liquorice Nanogel Versus Diode Laser as an Adjunctive Treatment for Patients With Periodontitis Stage Ⅲ.	Al-Azhar University	Phase 3	Completed	Diode Laser Therapy, Periodontal Disease, Liquorice Nanogel	27	Egypt	clinicaltrials.gov
May 22, 2026	NCT07602309	Tedlar Bag Stability of Volatile Sulfur Compounds for Remote Halitosis Diagnosis	University Hospital, Strasbourg, France	Not applicable	Not yet recruiting	Halitosis, Periodontal Diseases	100	France	clinicaltrials.gov
May 22, 2026	NCT07601685	MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study)	Inonu University	Observational	Completed	Periodontitis, Gingivitis and Periodontal Diseases, Biomarker Discovery and Validation, Pathways	48	Turkey (Türkiye)	clinicaltrials.gov
May 22, 2026	NCT07600710	Periodontal Disease in Patients With Lynch Syndrome	Rotundo Roberto	Observational	Not yet recruiting	Lynch Syndrome, Periodontal Disease	25	Italy	clinicaltrials.gov
May 19, 2026	NCT07596667	Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A...	Zeyad Nazar	Not applicable	Not yet recruiting	Periodontitis, Adult, Periodontal Diseases	21		clinicaltrials.gov
May 19, 2026	NCT07595757	Effect of Nano-Hyaluronic Acid in Intrabony Defects Treated With Minimally Invasive Non-Surgical Technique	Cairo University	Phase 1/2	Active not recruiting	Periodontal Disease, Periodontitis	28	Egypt	clinicaltrials.gov
May 18, 2026	NCT07593742	Smoking Cessation With Wearables to Improve General, Oral Health and Quality of Life	University of Salerno	Not applicable	Not yet recruiting	Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation, Smoking Dependence, Smoking...	102		clinicaltrials.gov
May 18, 2026	NCT07592416	Clinical, Microbiological and Immunological Effects of the Adjuvant Use of Systemic Antibiotics and Probiotics in the Non-surgical...	University of Sao Paulo	Early phase 1	Completed	Healthy Adult Participants, Periodontal Disease	60	Brazil	clinicaltrials.gov
May 12, 2026	NCT07581613	A Novel Proline-rich Peptide Hydrogel for Periodontal Regeneration in Adult Periodontitis Patients	Siddharth Shanbhag	Phase 1/2	Not yet recruiting	Periodontal Disease, Intrabony Periodontal Defects	40	Norway, Spain	clinicaltrials.gov
May 11, 2026	NCT07577258	Efficacy and Safety of HA35 Gel for Mild Gingival Recession and Periodontal Inflammation	Nakhia Impex LLC	Not applicable	Completed	Mild Gingival Recession, Periodontal Inflammation, Chronic Gingival Pain, Gingival Redness and Swelling, Gingival...	30	China	clinicaltrials.gov
May 8, 2026	NCT07575997	Comparison Between Different Interdental Brushes in Adults With Periodontal Disease.	Pierre Fabre Dermo Cosmetique	Not applicable	Recruiting	Periodontal Disease	88	Belgium	clinicaltrials.gov
May 8, 2026	NCT07575347	Periodontal Disease in Rare Renal Disorders (PERIO-RA-RE)	Stefan Lujinschi	Observational	Recruiting	Periodontal Disease, Periodontitis, CKD, Chronic Kidney Disease, Alport Syndrome, Fabry Disease, Lupus or SLE, Tuberous...	100	Romania	clinicaltrials.gov
May 8, 2026	NCT07574827	Candida Albicans in Syrian Patients With Periodontitis	Al-Hawash Private University	Observational	Recruiting	Periodontal Disease, Periodontal Diseases, Periodontitis	100	Syria	clinicaltrials.gov
May 7, 2026	NCT07573761	Evaluation of the Effectiveness of Odontogenic Grafts Obtained From Human Teeth on Bone Formation	Istanbul Saglik Bilimleri University	Observational	Enrolling by invitation	Alveolar Bone Loss, Periodontal Diseases, Periodontal Bone Loss, Periodontal Atrophy, Bone Diseases, Bone Resorption	21	Turkey (Türkiye)	clinicaltrials.gov
May 6, 2026	NCT07571850	Gingival Crevicular Fluid Levels of Prolactin Hormone in Obese Patients With Stage ii and Iii Periodontitis Before and After Non-surgical...	Alexandria University	Not applicable	Completed	Obesity, Periodontal Diseases	26	Egypt	clinicaltrials.gov
May 1, 2026	NCT07563192	Evaluation of the Effect of Smoking on Pyroptosis in Periodontal Pathogenesis	Suleyman Demirel University	Observational	Active not recruiting	Periodontitis, Gingivitis, Periodontal Diseases, Smoking ( Cigarette)	113	Turkey (Türkiye)	clinicaltrials.gov
April 27, 2026	NCT07553286	Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial	Johns Hopkins Bloomberg School of Public Health	Phase 3	Not yet recruiting	Preterm Birth, Low Birth Weight, Small Vulnerable Newborn, Small-for-gestational Age, Periodontal Disease	2,280		clinicaltrials.gov
April 24, 2026	NCT07551310	Lymphocyte Subpopulations in Peripheral Giant Cell Granuloma	Ataturk University	Observational	Completed	Peripheral Giant Cell Granuloma, Gingival Lesions, Gingival Enlargement	28	Turkey (Türkiye)	clinicaltrials.gov
April 24, 2026	NCT07551115	Association Between Periodontal Status and the Prevalence of Entamoeba Gingivalis and Trichomonas Tenax	Abant Izzet Baysal University	Observational	Completed	Gingivitis and Periodontal Diseases, Periodontitis	120	Turkey (Türkiye)	clinicaltrials.gov
April 22, 2026	NCT07545109	Evaluation of OHIP-14 and OSHIP-14 in Patients With Varying Periodontal Disease	Abant Izzet Baysal University	Observational	Active not recruiting	Periodontal Disease	300	Turkey (Türkiye)	clinicaltrials.gov
April 21, 2026	NCT07542275	Endoscopic Assessment of Schneiderian Membrane Perforation During Osseodensification-mediated Transcrestal Sinus Floor Elevation With...	Saint-Joseph University	Not applicable	Completed	Sinusitis, Periodontal Disease	6	Lebanon	clinicaltrials.gov
April 20, 2026	NCT07540624	Efficacy of Chlorhexidine and Morus Nigra Mouthwashes After Periodontal Treatment	Inonu University	Not applicable	Completed	Periodontitis, Periodontal Disease	48	Turkey (Türkiye)	clinicaltrials.gov
April 17, 2026	NCT07536204	Characterization of JAK1 and JAK2 Activation in Gingival Tissues During Homeostasis and Periodontitis	University of Chile	Observational	Recruiting	Periodontitis, Periodontal Diseases, Periodontal Inflammation, Gingival Diseases, Periodontal Attachment Loss	30	Chile	clinicaltrials.gov
April 16, 2026	NCT07534306	Impact of Atypical Swallowing on Periodontal Health in Adults	University of Roma La Sapienza	Observational	Completed	Atypical Swallowing, Periodontal Disease	125	Italy	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Saglik Bilimleri Universitesi	9	September 16, 2026
Cairo University	6	October 19, 2026
Abant Izzet Baysal University	5	August 28, 2026
Mansoura University	5	July 30, 2026
University of Guarulhos	5	July 7, 2026
Colgate Palmolive	4	September 8, 2026
Inonu University	4	August 12, 2026
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University	4	August 4, 2026
Suleyman Demirel University	4	July 23, 2026
Ankara University	4	July 15, 2026
Al-Azhar University	4	July 8, 2026
Recep Tayyip Erdogan University Training and Research Hospital	4	June 24, 2026
Biruni University	3	October 20, 2026
Universidad Complutense de Madrid	3	September 17, 2026
University of Roma La Sapienza	3	May 22, 2026
Tuğba ŞAHİN	3	February 20, 2026
Uskudar University	3	February 19, 2026
Rungta College of Dental Sciences and Research	3	December 30, 2025
Medipol University	3	December 9, 2025
University of Pavia	3	July 28, 2025

By phase

Phase	New trials	Latest
Not applicable	113	November 9, 2026
Observational	106	October 30, 2026
Phase 4	13	September 8, 2026
Phase 3	8	October 6, 2026
Early phase 1	6	July 13, 2026
Phase 1/2	4	August 27, 2026
Phase 1	2	August 28, 2026
Phase 2	2	December 19, 2025
Phase 2/3	1	February 20, 2026

By country

Country	New trials	Latest
Turkey (Türkiye)	83	November 9, 2026
Egypt	22	October 19, 2026
Italy	16	October 30, 2026
United States	9	June 2, 2026
Brazil	8	September 3, 2026
India	7	October 19, 2026
China	7	August 4, 2026
Spain	6	September 17, 2026
Slovenia	4	November 3, 2026
Pakistan	4	August 17, 2026
France	4	June 16, 2026
Romania	4	June 11, 2026
United Kingdom	4	February 12, 2026
Poland	4	December 15, 2025
Saudi Arabia	3	September 24, 2026
Lebanon	3	July 24, 2026
Chile	3	April 17, 2026
Hungary	3	December 22, 2025
United Arab Emirates	2	July 1, 2026
Belgium	2	May 8, 2026
Greece	2	March 13, 2026
Iraq	2	January 26, 2026
Sweden	2	December 29, 2025
Malaysia	2	December 19, 2025
Vietnam	2	December 2, 2025

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.