Data / New clinical trials / Osteoarthritis, Knee

Osteoarthritis, Knee trials: 525 new since Nov 2024

Name: New Osteoarthritis, Knee clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Osteoarthritis, Knee clinical trials: 525 rows for $26.25, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 30 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/osteoarthritis-knee, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 9, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

525 clinical studies in Osteoarthritis, Knee were first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026; 60 have an industry sponsor and 313 are recruiting or about to. The newest, NCT07926373, was posted on November 9, 2026: Proximal, Mid, and Distal Adductor Canal Block for Pain Control After Total Knee Arthroplasty (Bursa City Hospital).

The request: Every new Osteoarthritis, Knee clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

525New trials
60Industry sponsored
313Recruiting or not yet
November 9, 2026Latest posted

Newest trials

The newest 100 of 525, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 9, 2026	NCT07926373	Proximal, Mid, and Distal Adductor Canal Block for Pain Control After Total Knee Arthroplasty	Bursa City Hospital	Not applicable	Not yet recruiting	Postoperative Pain, Arthroplasty, Replacement, Knee, Knee Osteoarthritis	120		clinicaltrials.gov
November 9, 2026	NCT07924748	Balance Training and Resting Brain Activity in Knee Osteoarthritis: A Randomized Controlled Trial	Qingdao Municipal Hospital	Not applicable	Completed	Osteoarthritis, Knee	74	China	clinicaltrials.gov
November 6, 2026	NCT07921563	The Feasibility of a Virtual/Home-based OA Treatment Program in Older Adults With OA and Multimorbidity	Dartmouth-Hitchcock Medical Center	Not applicable	Not yet recruiting	Osteoarthritis of the Knee	50	United States	clinicaltrials.gov
November 5, 2026	NCT07920120	Effects of Virtual Reality Environments on Walking in Adults With and Without Knee Osteoarthritis	University of Primorska	Not applicable	Recruiting	Knee Osteoarthritis	60	Lithuania, Slovenia	clinicaltrials.gov
November 5, 2026	NCT07919678	A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)	Pfizer	Phase 3	Recruiting	Obesity, Overweight, Osteoarthritis of the Knee	656	Canada, United States	clinicaltrials.gov
November 5, 2026	NCT07919535	Effect of Local Heat Applications on Musculoskeletal Pain, Stiffness and Physical Function for Patients With Knee Osteoarthritis	Ain Shams University	Not applicable	Completed	Knee Osteoarthritis (Knee OA)	100	Egypt	clinicaltrials.gov
November 4, 2026	NCT07917559	EFFECT OF ADDING BLOOD FLOW RESTRICTION TRAINING TO CLOSED CHAIN EXERCISE IN KNEE OSTEOARTHRITIS	Rasha Abdel Kader Abdel Azeem Khtab	Not applicable	Not yet recruiting	Knee Osteoarthritis	60	Egypt	clinicaltrials.gov
November 4, 2026	NCT07915609	A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2...	Pfizer	Phase 3	Recruiting	Obesity, Overweight and/or Obesity, Knee Osteoarthritis, Diabetes Melliuts, Type 2	756	United States	clinicaltrials.gov
November 3, 2026	NCT07914036	Patient Satisfaction After Robotic-Assisted Versus Conventional Total Knee Arthroplasty	Ain Shams University	Not applicable	Not yet recruiting	Osteoarthritis (Knee), Robotic Assisted Arthroplasty	70	Egypt	clinicaltrials.gov
November 3, 2026	NCT07913295	Comparative Effect of Dual Task Training and Rhythmic Stabilization in Knee Osteoarthritis Patients	University of Management and Technology Lahore	Not applicable	Active not recruiting	Knee Osteoarthritis	26	Pakistan	clinicaltrials.gov
November 3, 2026	NCT07912333	Wearable Device Guided Exercise for Patients on Total Knee Arthroplasty Wait-list	Chinese University of Hong Kong	Not applicable	Not yet recruiting	Knee Osteoarthristis	106	Hong Kong	clinicaltrials.gov
November 3, 2026	NCT07911696	Comparative Effectiveness and Safety of Two Hyaluronic Acid Products in Knee Osteoarthritis	Coordinación de Investigación en Salud, Mexico	Observational	Not yet recruiting	Osteoarthritis, Knee	160	Mexico	clinicaltrials.gov
November 2, 2026	NCT07908589	Tempo-controlled Low-load Resistance Training in Patients With Knee Osteoarthritis.	University of Management and Technology Lahore	Not applicable	Not yet recruiting	Knee Osteoarthritis	32	Pakistan	clinicaltrials.gov
October 29, 2026	NCT07904741	The Effect of Different Exercise Training Programs on Muscle Oxygenation in Individuals With Knee Osteoarthritis	Bahçeşehir University	Not applicable	Recruiting	Osteoarthritis of Knee	60	Turkey (Türkiye)	clinicaltrials.gov
October 29, 2026	NCT07903142	Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal Disorders	BTL Industries Ltd.	Not applicable	Not yet recruiting	Low Back Pain, Radicular Syndrome, Sacroiliac Joint Dysfunction, Shoulder Impingement Syndrome, Rotator Cuff...	60	Czechia	clinicaltrials.gov
October 28, 2026	NCT07901881	The Effect of Theory-driven Physiotherapy on Physical Activity in Knee OA.	Mark van Loo	Not applicable	Not yet recruiting	Knee Osteoarthritis	20	Netherlands	clinicaltrials.gov
October 28, 2026	NCT07901790	Autologous Adipose-Derived Stem Cell Injections for Knee Osteoarthritis	Yonsei University	Not applicable	Recruiting	Osteoarthritis, Knee, Knee Osteoarthritis	165	South Korea	clinicaltrials.gov
October 28, 2026	NCT07901374	Genicular Nerve Radiofrequency Ablation Versus Hyaluronic Acid Injection for Knee Osteoarthritis Pain	Hospital Universitari Joan XXIII de Tarragona.	Not applicable	Not yet recruiting	Knee Osteoarthritis, Chronic Knee Pain	70	Spain	clinicaltrials.gov
October 28, 2026	NCT07901348	GENIVS Block Versus Adductor Canal Block After Total Knee Arthroplasty	Bakirkoy Dr. Sadi Konuk Research and Training Hospital	Not applicable	Not yet recruiting	Arthroplasty, Replacement, Knee, Pain, Postoperative, Osteoarthritis, Knee	74	Turkey (Türkiye)	clinicaltrials.gov
October 28, 2026	NCT07901153	Platelet-Rich Plasma, Hyaluronic Acid, or Their Combination for Knee Osteoarthritis in Athletes	University of Sao Paulo General Hospital	Not applicable	Not yet recruiting	Knee Osteoarthritis	300	Brazil	clinicaltrials.gov
October 27, 2026	NCT07898501	SVF Cellular Composition, Secretome, and Responses in Knee Osteoarthritis	Yonsei University	Observational	Recruiting	Osteoarthritis, Knee	20	South Korea	clinicaltrials.gov
October 23, 2026	NCT07892144	Effects of Low-Load Blood Flow Restriction Resistance Training With and Without Hip Abductor Strengthening in Patients With Knee...	University of Management and Technology Lahore	Not applicable	Not yet recruiting	Knee Osteoarthritis	44	Pakistan	clinicaltrials.gov
October 23, 2026	NCT07891351	Effects Of Sensor Assisted Neuro-muscular Exercise Vs Electrical Stimulation On Bio-mechnical And Functional Parameters In Grade II And III...	Ziauddin University	Not applicable	Completed	Knee Arthritis Osteoarthritis, Neuromuscular Adaptations	40	Pakistan	clinicaltrials.gov
October 22, 2026	NCT07890155	Effect of Resistance Exercises on Serum IGF-1 Levels in Knee Osteoarthritis	Sisli Hamidiye Etfal Training and Research Hospital	Not applicable	Recruiting	Osteoarthritis (Knee), Metabolic Syndrome (MetS)	86	Turkey (Türkiye)	clinicaltrials.gov
October 22, 2026	NCT07888920	Effects of Visual and Vestibular Rehabilitation in Individuals With Knee Osteoarthritis	Istanbul Aydın University	Not applicable	Not yet recruiting	Knee Osteoarthritis, Visual Rehabilitation, Vestibular Rehabilitation, Postural Stability, Balance, Pain, Functional...	42	Turkey (Türkiye)	clinicaltrials.gov
October 22, 2026	NCT07887893	Extracorporeal Shock Wave Therapy in the Treatment of Periarticular Bone Marrow Edema in Patients With Knee Osteoarthritis	Dokuz Eylul University	Not applicable	Recruiting	Knee Arthritis, Osteoarthritis, Bone Marrow Edema of the Knee, Bone Marrow Edema	24	Turkey (Türkiye)	clinicaltrials.gov
October 21, 2026	NCT07886697	Low-Dose Radiotherapy for Painful Knee Osteoarthritis	Universidad Rey Juan Carlos	Not applicable	Not yet recruiting	Knee Osteoarthritis	283	Spain	clinicaltrials.gov
October 20, 2026	NCT07883824	Aquatic Exercise in Patients With Knee Osteoarthritis	Kirsehir Ahi Evran Universitesi	Not applicable	Recruiting	Central Sensitization, Knee Osteoarthristis, Aquatic	60	Turkey (Türkiye)	clinicaltrials.gov
October 20, 2026	NCT07882316	Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty	Balikesir Ataturk City Hospital	Observational	Recruiting	Knee Osteoarthritis, Multimorbidity	230	Turkey (Türkiye)	clinicaltrials.gov
October 20, 2026	NCT07881861	Cartilage Biomarker Response to Acute Mechanical Loading in Women With Knee Osteoarthritis: Comparison by Antiresorptive Treatment Status	Sisli Hamidiye Etfal Training and Research Hospital	Observational	Recruiting	Knee Osteoarthritis	105	Turkey (Türkiye)	clinicaltrials.gov
October 19, 2026	NCT07881445	Subchondral Drilling Diameter During CARTISTEM Implantation for Knee Cartilage Defects	Yonsei University	Not applicable	Recruiting	Osteoarthritis, Knee, Articular Cartilage Defects of the Knee	60	South Korea	clinicaltrials.gov
October 19, 2026	NCT07879664	Bipolar Versus Cooled Radiofrequency Ablation for Gonarthrosis	Saglik Bilimleri Universitesi	Not applicable	Not yet recruiting	Gonarthrosis	80	Turkey (Türkiye)	clinicaltrials.gov
October 15, 2026	NCT07876752	Clinical Importance of Occult Suprapatellar Effusion in Knee Osteoarthritis	Mardin Artuklu University	Observational	Not yet recruiting	Knee Osteoarthritis	105	Turkey (Türkiye)	clinicaltrials.gov
October 15, 2026	NCT07876310	A Randomized Comparison of the Efficacy of the IPACK Block Versus the Popliteal Plexus Block for Posterior Knee Analgesia, in Patients...	Clinica Santa Maria	Not applicable	Not yet recruiting	Osteoarthritis, Knee, Postoperative Pain	136		clinicaltrials.gov
October 15, 2026	NCT07875725	Wearable Knee-Assisted Rehabilitation for Range of Motion and Muscle Strength After Total Knee Arthroplasty	University of Chile	Not applicable	Not yet recruiting	Total Knee Arthroplasty Recovery, Knee Osteoarthritis	80	Chile	clinicaltrials.gov
October 15, 2026	NCT07875647	Person-Centred Digital Rehabilitation for Knee Osteoarthritis	Mälardalen University	Observational	Not yet recruiting	Knee Osteoarthritis, Physical Activity Behaviour	500	Sweden	clinicaltrials.gov
October 15, 2026	NCT07875543	Comparison of the Therapeutic Effects of Lyophilized Platelet-rich Plasma Lysate and Dextrose Prolotherapy in Knee Osteoarthritis	Taichung Veterans General Hospital	Phase 2	Completed	Knee Osteoarthritis, Platelet-rich Plasma (PRP)	39	Taiwan	clinicaltrials.gov
October 15, 2026	NCT07875296	Lysyl Oxidase and Lysyl Hydroxylase Levels in Knee Osteoarthritis	Afyonkarahisar Health Sciences University	Observational	Recruiting	Knee Osteoarthritis	200	Turkey (Türkiye)	clinicaltrials.gov
October 15, 2026	NCT07875231	Dexmedetomidine Infusion and Iscemia and Reperfusion Injury	Diskapi Yildirim Beyazit Education and Research Hospital	Phase 4	Completed	Gonarthrosis	60		clinicaltrials.gov
October 13, 2026	NCT07872280	Neuromuscular Facilitation Protocol on Pain, Range and Function in KOA	Riphah International University	Not applicable	Completed	Knee Osteoarthristis	54	Pakistan	clinicaltrials.gov
October 13, 2026	NCT07870967	Undenatured Type II Collagen for Knee Osteoarthritis Pain	Universidad Católica San Antonio de Murcia	Not applicable	Recruiting	Osteoarthritis, Knee	120	Spain	clinicaltrials.gov
October 13, 2026	NCT07870031	Clinical Evaluation of TrHCROSS® for Different Joints	i+Med S.Coop.	Not applicable	Not yet recruiting	Joint Osteoarthritis, Knee Osteoarthristis, Hip Ostearthritis, Shoulder Osteoarthritis	150		clinicaltrials.gov
October 13, 2026	NCT07869771	The Effect of Pulsed Radiofrequency Ablation of the Genicular Nerve on Pain, Balance, and Proprioception in Patients With Chronic Knee...	Ankara City Hospital Bilkent	Not applicable	Completed	Knee Osteoarthritis (OA), Genicular Nerves Block, Radiofrequency Ablation	28	Turkey (Türkiye)	clinicaltrials.gov
October 9, 2026	NCT07869680	Functional Capacity Differences in Knee Osteoarthritis With Similar Pain Severity	Mardin Artuklu University	Observational	Recruiting	Knee Osteoarthritis	120	Turkey (Türkiye)	clinicaltrials.gov
October 9, 2026	NCT07868770	US-Guided Saphenous Block in Knee OA	Gaziler Physical Medicine and Rehabilitation Education and Research Hospital	Not applicable	Not yet recruiting	Knee Osteoarthritis, Osteoarthritis, Knee, Gonarthrosis, Knee Pain	60	Turkey (Türkiye)	clinicaltrials.gov
October 9, 2026	NCT07868224	Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials	Jiangxi University of Traditional Chinese Medicine	Not applicable	Not yet recruiting	Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis	30	China	clinicaltrials.gov
October 9, 2026	NCT07867405	The Effect of Tail Fat Application on Joint Pain, Joint Stiffness, and Daily Living Activities in Patients With Gonarthrosis	Inonu University	Not applicable	Recruiting	Gonarthrosis	66	Turkey (Türkiye)	clinicaltrials.gov
October 8, 2026	NCT07866378	The Bone Cement Penetration in Medial Fixed-bearing Unicompartmental Knee Arthroplasty	Tianjin Union Medical Center	Observational	Completed	Knee Osteoarthritis	88	China	clinicaltrials.gov
October 6, 2026	NCT07859878	Efficacy of High-Intensity Laser Therapy in Early-Stage Symptomatic Knee Osteoarthritis	Ege University	Not applicable	Completed	Osteoarthritis, Knee	39	Turkey (Türkiye)	clinicaltrials.gov
October 5, 2026	NCT07857954	Comparison of Leucocyte-rich PRP and Leucocyte-poor PRP in Treating Mild to Moderate Knee Osteoarthritis	St. Catherine Specialty Hospital	Not applicable	Completed	Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3), Knee Osteoarthritis, PRP, Platelet-rich Plasma (PRP)	59	Croatia	clinicaltrials.gov
October 2, 2026	NCT07855367	Cryoneurolysis Versus Bipolar Radiofrequency Ablation of Genicular Nerves for Pain Relief in Symptomatic Knee Osteoarthritis	National Cancer Institute, Egypt	Not applicable	Recruiting	Cryoneurolysis, Bipolar Radiofrequency Ablation, Genicular Nerves, Pain Relief, Symptomatic, Knee Osteoarthritis	30	Egypt	clinicaltrials.gov
October 2, 2026	NCT07853885	Intraosseous Tranexamic Acid for Reducing Blood Loss in Total Knee Arthroplasty	The Second Affiliated Hospital of Kunming Medical University	Phase 4	Not yet recruiting	Knee Osteoarthritis	70	China	clinicaltrials.gov
October 1, 2026	NCT07853170	3-Needle vs 5-Needle of Genicular Nerve Block on Pain and Quality of Life in Knee Osteoarthritis	Tanta University	Not applicable	Recruiting	3-Needle, 5-Needle, Genicular Nerve Block, Pain, Quality of Life, Knee Osteoarthritis	80	Egypt	clinicaltrials.gov
September 29, 2026	NCT07845838	The Effect of Training on Oxidative Stress in Patients With kneeOA.	Mariette Boshuis	Not applicable	Recruiting	Knee Osteoarthritis, Oxidative Stress	20	Netherlands	clinicaltrials.gov
September 28, 2026	NCT07843784	Chatbot-based Pain Management for People With Knee Osteoarthritis	The Hong Kong Polytechnic University	Not applicable	Enrolling by invitation	Knee Osteoarthritis	36	Hong Kong	clinicaltrials.gov
September 24, 2026	NCT07838012	Feasibility of an Early Home-based Cycling Intervention After Knee Arthroplasty	Central Jutland Regional Hospital	Not applicable	Recruiting	Knee Osteoarthritis, Knee Arthroplasty	24	Denmark	clinicaltrials.gov
September 23, 2026	NCT07837284	Medication vs. Meditation for Chronic Knee Osteoarthritis	Florida State University	Early phase 1	Not yet recruiting	Knee Osteoarthristis	30		clinicaltrials.gov
September 23, 2026	NCT07835672	Selective Nerve Ablation for Chronic Knee Pain: A Retrospective Study	Michał Bartoszewicz	Observational	Completed	Knee Osteoarthritis, Chronic Knee Pain	746	Poland	clinicaltrials.gov
September 22, 2026	NCT07834827	Popliteus and Quadriceps Muscle Thickness and Clinical Parameters in Knee Osteoarthritis	Afyonkarahisar Health Sciences University	Observational	Active not recruiting	Knee Arthritis Osteoarthritis, Balance Assessment	130	Turkey (Türkiye)	clinicaltrials.gov
September 22, 2026	NCT07834034	Daycase Hip and Knee Arthroplasty in Møre and Romsdal Trial	Helse Møre og Romsdal HF	Observational	Not yet recruiting	Knee Osteoarthritis, Hip Osteoarthritis, Osteonecrosis, Osteoarthritis	300	Norway	clinicaltrials.gov
September 22, 2026	NCT07833488	Exploring Factors Linked to Worsening Over Time in People With Early-stage Knee Osteoarthritis and Those With Prior Proven Acute Knee...	Imperial College London	Observational	Recruiting	Knee Osteoarthritis	200	United Kingdom	clinicaltrials.gov
September 22, 2026	NCT07833462	Efficacy of Thread-Embedding Acupuncture Using the Longitudinal Oblique Technique From BL40 Toward BL57 on KOOS Scores and Joint Range of...	Universitas Indonesia	Not applicable	Not yet recruiting	Knee Osteoarthritis	44	Indonesia	clinicaltrials.gov
September 22, 2026	NCT07832682	Neurofeedback for Pain Sensitization in Knee Osteoarthritis	Northeastern University	Not applicable	Not yet recruiting	Knee Osteoarthritis	50		clinicaltrials.gov
September 18, 2026	NCT07828561	Clinical Outcomes of Intraarticular Platelet-Rich Plasma Injection in Knee Osteoarthritis	KIST Medical and Teaching Hospital	Not applicable	Completed	Knee Osteoarthritis, Osteoarthritis (OA), Degenerative Joint Disease of Knee, Knee Pain	59	Nepal	clinicaltrials.gov
September 18, 2026	NCT07827443	mFFE MRI Versus CT for Cortical Bone Evaluation in Knee Osteoarthritis	Assiut University	Observational	Not yet recruiting	Osteoarthritis, Knee, Bone Diseases	80		clinicaltrials.gov
September 17, 2026	NCT07825350	HTO and Tranexamic Acid Study	Western University, Canada	Phase 3	Not yet recruiting	Osteoarthritis, Knee	200		clinicaltrials.gov
September 16, 2026	NCT07823673	Comparing Pain Science Education to Biomedical Education for People With Knee Osteoarthritis: A Randomized Controlled Trial	McMaster University	Not applicable	Not yet recruiting	Knee Arthritis Osteoarthritis	82		clinicaltrials.gov
September 15, 2026	NCT07819461	A Study to Evaluate Efficacy and Safety of a Single Intra-Articular Injection of HL-01 in the Treatment of Pain in Symptomatic Knee...	IBSA Institut Biochimique SA	Phase 3	Not yet recruiting	Osteo Arthritis of the Knee	704		clinicaltrials.gov
September 10, 2026	NCT07813078	Anti-Gravity Treadmill Gait Training for Knee Osteoarthritis	University of Rzeszow	Not applicable	Recruiting	Knee Osteoarthritis	80	Poland	clinicaltrials.gov
September 8, 2026	NCT07806318	Coach2Move: Physical Therapy to Improve Physical Activity in Individuals With Chronic MSK Conditions	University of Utah	Observational	Completed	Osteoarthritis,Knee, Osteoarthritis Knees Both, Osteoarthritis Hip, Low Back Pain, Chronic Pain, Hip Pain Chronic, Knee...	94	United States	clinicaltrials.gov
September 4, 2026	NCT07805161	Bipolar RFA Versus Phenol Neurolysis for Knee Osteoarthritis Pain	Saglik Bilimleri Universitesi	Not applicable	Completed	Gonarthrosis	69	Turkey (Türkiye)	clinicaltrials.gov
September 4, 2026	NCT07804446	Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection	University of Chicago	Not applicable	Recruiting	Osteoarthitis, Osteoarthritic Knee Pain, Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis in the...	140	United States	clinicaltrials.gov
September 4, 2026	NCT07804212	The Effectiveness of Strength Training and Self-management in Reducing Symptoms for Individuals With Knee Osteoarthritis	Pingtung Veterans General Hospital	Not applicable	Not yet recruiting	Osteoarthritis	100	Taiwan	clinicaltrials.gov
September 4, 2026	NCT07804199	taVNS in Veterans With Knee OA (AVAHCS)	VA Office of Research and Development	Not applicable	Recruiting	Knee Osteoarthritis	40	United States	clinicaltrials.gov
September 4, 2026	NCT07803887	Effect of Adding a Biceps Femoris Short Head Block to Adductor Canal Block for Analgesia After Total Knee Arthroplasty	Antalya Training and Research Hospital	Not applicable	Not yet recruiting	Knee Osteoarthritis (OA), Postoperative Pain	122	Turkey (Türkiye)	clinicaltrials.gov
September 2, 2026	NCT07800780	Effects of Different Collagen Formulations on Knee Osteoarthritis	Cihangir Türemiş	Not applicable	Not yet recruiting	Osteoarthritis, Knee	45	Turkey (Türkiye)	clinicaltrials.gov
September 2, 2026	NCT07798973	Effects of Tele Rehabilitation vs Onsite Rehabilitation on Balance, Mobility, and Risk of Fall Among Geriatric Population With Knee...	Ibadat International University, Islamabad	Not applicable	Completed	Knee Osteoarthritis, Falls, Balance Impairment, Mobility Limitation	44	Pakistan	clinicaltrials.gov
August 27, 2026	NCT07790146	Improvement of Total Knee Arthroplasty Effectiveness Using Preoperative Prehabilitation	Samara State Medical University	Not applicable	Completed	Knee Osteoarthritis, Total Knee Arthroplasty	64	Russia	clinicaltrials.gov
August 27, 2026	NCT07789340	Unipolar Versus Bipolar Radiofrequency Ablation in Knee Osteoarthritis Pain	Tanta University	Not applicable	Recruiting	Bipolar Radiofrequency Ablation, Unipolar Radiofrequency Ablation, Knee Osteoarthritis, Pain	64	Egypt	clinicaltrials.gov
August 25, 2026	NCT07786038	E-Health Lifestyle Intervention for Arthritis: A Pilot RCT on Feasibility	The University of Hong Kong	Not applicable	Not yet recruiting	Knee Osteoarthristis, Obesity & Overweight	50	Hong Kong	clinicaltrials.gov
August 25, 2026	NCT07785401	Efficacy of Platelet-Rich Plasma Added to Hyaluronic Acid in Knee Osteoarthritis	Implai Sp z o.o	Not applicable	Recruiting	Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA), Osteoarthritis (OA) of the Knee	50	Poland	clinicaltrials.gov
August 25, 2026	NCT07784998	Gender Based Comparison of the Effects of Sensory Modulated Graded Weight Bearing Physiotherapy In Adults With Knee Osteoarthritis	Shifa Tameer-e-Millat University	Not applicable	Recruiting	Knee Osteoarthristis	52	Pakistan	clinicaltrials.gov
August 25, 2026	NCT07784907	Efficacy of Platelet-Rich Plasma Combined With Hyaluronic Acid in Knee Osteoarthritis	Implai Sp z o.o	Not applicable	Recruiting	Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA), Osteoarthritis (OA) of the Knee	100	Poland	clinicaltrials.gov
August 21, 2026	NCT07779122	Wearable Electrogoniometry-Based Telerehabilitation After Total Knee Arthroplasty	University of Chile	Not applicable	Completed	TKA, Knee Osteoarthritis	82	Chile	clinicaltrials.gov
August 20, 2026	NCT07777757	New Robotic Knee Surgery: Does Implant Type Affect Alignment Accuracy?	The University of Hong Kong	Not applicable	Recruiting	Knee Osteoarthristis	100	Hong Kong	clinicaltrials.gov
August 19, 2026	NCT07774195	Efficacy of AI-Driven and Traditional Physical Therapy Programs in Patients With Knee Osteoarthritis	Cairo University	Not applicable	Not yet recruiting	Knee Osteoarthritis	40	Egypt	clinicaltrials.gov
August 19, 2026	NCT07773480	Formative Evaluation of a Mobile Application Facilitated Self-directed Rehabilitation Programme for Knee Osteoarthritis	Singapore General Hospital	Not applicable	Not yet recruiting	Knee Osteoarthritis	30	Singapore	clinicaltrials.gov
August 18, 2026	NCT07769593	MORA Cure for Knee Osteoarthritis With Anterior Knee Pain	EverEx Inc.	Not applicable	Active not recruiting	Knee Osteoarthritis, Anterior Knee Pain	44	South Korea	clinicaltrials.gov
August 17, 2026	NCT07768709	Holistic Healing for Knee Osteoarthritis	All India Institute of Medical Sciences, Jodhpur	Not applicable	Not yet recruiting	Knee Osteoarthritis (Knee OA)	300	India	clinicaltrials.gov
August 17, 2026	NCT07767812	Effects of Motivational Interviewing on Pain Self-Efficacy and Exercise Behavior in Individuals With Knee Osteoarthritis	Kutahya Health Sciences University	Not applicable	Recruiting	Knee Arthritis Osteoarthritis	56	Turkey (Türkiye)	clinicaltrials.gov
August 17, 2026	NCT07767409	Outpatient Physiotherapy vs. mHealth Exercise and Self-Management for Knee Osteoarthritis (MOKneeTOR)	Singapore General Hospital	Not applicable	Recruiting	Knee Osteoarthristis	160	Singapore	clinicaltrials.gov
August 14, 2026	NCT07766330	Effect of Nonsteroidal Anti-Inflammatory Drug Restriction on the Efficacy of Platelet-Rich Plasma in Knee Osteoarthritis	Federal University of São Paulo	Not applicable	Not yet recruiting	Osteoarthritis, Knee	90	Brazil	clinicaltrials.gov
August 12, 2026	NCT07759336	Personalized Analgesia Through Central Nervous System Engagement to Unlock Performance	Benedict Alter	Phase 4	Recruiting	Knee Osteoarthritis (Knee OA), Chronic Pain, Chronic Knee Pain	85	United States	clinicaltrials.gov
August 11, 2026	NCT07757581	Customized Knee Arthroplasty With or Without Posterior Cruciate Ligament Retention: A CR-PS Approach	Groupe Hospitalier Diaconesses Croix Saint-Simon	Not applicable	Active not recruiting	Knee Arthroplasty, Osteoarthritis, Knee	140	France	clinicaltrials.gov
August 11, 2026	NCT07757464	Pre-emptive Insulin to Prevent High Glucose After a Knee Steroid Injection in Adults With Type 2 Diabetes	Shifa International Hospital	Phase 1/2	Active not recruiting	Diabetes Mellitus, Type 2, Hyperglycemia Due to Type 2 Diabetes Mellitus, Osteoarthritis, Knee	125	Pakistan	clinicaltrials.gov
August 10, 2026	NCT07754175	A Multicenter, Open-Label, Single-Arm Extension Study to Evaluate the Safety and Efficacy of FURESTEM-OA-Kit Inj. in Knee Osteoarthritis...	Kang Stem Biotech Co., Ltd.	Observational	Recruiting	Knee Osteoarthritis	36	South Korea	clinicaltrials.gov
August 5, 2026	NCT07746843	The Efficacy and Safety Study of 2107 Injection in Subjects With Mild to Moderate Knee Osteoarthritis	BioRegen Biomedical (Changzhou) Co., Ltd	Not applicable	Not yet recruiting	Mild Knee Osteoarthritis, Moderate Knee Osteoarthritis	286	Poland, Spain, United Kingdom	clinicaltrials.gov
August 5, 2026	NCT07746466	Efficacy of Bioactive Collagen Peptide Compared to Glucosamine and Chondroitin Sulphate in Grade I-III Knee Osteoarthritis	Liaquat National Hospital & Medical College	Not applicable	Completed	Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3)	150	Pakistan	clinicaltrials.gov
August 4, 2026	NCT07745387	Effect of a Topical Cetylated Fatty Acid Cream on Pain Relief in Patients With Knee Osteoarthritis	Pharmanutra S.p.a.	Not applicable	Completed	Knee Osteoarthristis	156	Georgia	clinicaltrials.gov
August 4, 2026	NCT07744789	Knee Ligament Stiffness Across Ethnicities Before and After Osteoarthritis Treatment	National Taiwan University Hospital	Observational	Recruiting	Knee Osteoarthritis	208	Taiwan	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Riphah International University	25	October 13, 2026
Ankara City Hospital Bilkent	8	October 13, 2026
Tanta University	7	October 1, 2026
Assiut University	7	September 18, 2026
Cairo University	7	August 19, 2026
Yonsei University	6	October 28, 2026
VA Office of Research and Development	6	September 4, 2026
The Hong Kong Polytechnic University	5	September 28, 2026
Poznan University of Medical Sciences	5	June 30, 2026
Ain Shams University	4	November 5, 2026
Universitas Indonesia	4	September 22, 2026
Lahore University of Biological and Applied Sciences	4	July 28, 2026
University of Lahore	4	July 14, 2026
Kanuni Sultan Suleyman Training and Research Hospital	4	June 16, 2026
Vastra Gotaland Region	4	February 3, 2026
Superior University	4	March 30, 2025
University of Management and Technology Lahore	3	November 3, 2026
Sisli Hamidiye Etfal Training and Research Hospital	3	October 22, 2026
University of Chicago	3	September 4, 2026
The University of Hong Kong	3	August 25, 2026

By phase

Phase	New trials	Latest
Not applicable	357	November 9, 2026
Observational	89	November 3, 2026
Phase 3	21	November 5, 2026
Phase 2	17	October 15, 2026
Phase 4	14	October 15, 2026
Phase 1	9	June 17, 2026
Phase 1/2	7	August 11, 2026
Phase 2/3	6	July 14, 2026
Early phase 1	5	September 23, 2026

By country

Country	New trials	Latest
Turkey (Türkiye)	102	October 29, 2026
United States	61	November 6, 2026
Pakistan	54	November 3, 2026
Egypt	34	November 5, 2026
China	25	November 9, 2026
Poland	19	September 23, 2026
Spain	17	October 28, 2026
Taiwan	14	October 15, 2026
South Korea	13	October 28, 2026
Canada	12	November 5, 2026
Hong Kong	10	November 3, 2026
France	10	August 11, 2026
United Kingdom	9	September 22, 2026
Brazil	7	October 28, 2026
Sweden	7	October 15, 2026
Denmark	7	September 24, 2026
Indonesia	7	September 22, 2026
Italy	7	July 2, 2026
Australia	6	April 15, 2026
Belgium	6	March 18, 2026
Mexico	5	November 3, 2026
Saudi Arabia	5	June 10, 2026
Netherlands	4	October 28, 2026
Chile	4	October 15, 2026
Norway	4	September 22, 2026

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.