Data / New clinical trials / Glioma
New Glioma clinical trials: 176 posted since Nov 2024
The full list. New Glioma clinical trials: 176 rows for $8.80, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 6 rows a month. The new rows come each week by email, $19 a month.
Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.
For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/glioma, and every list with its row count and price is at https://specstream.ai/data/lists.json.
Updated November 2, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).
176 clinical studies in glioma were first posted on ClinicalTrials.gov from November 12, 2024 to November 2, 2026; 39 have an industry sponsor and 137 are recruiting or about to. The newest, NCT07909460, was posted on November 2, 2026: Blood Brain Barrier Dysfunction in Glioma and Epileptogenesis (University College, London).
The request: Every new Glioma clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.
SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.
- 176New trials
- 39Industry sponsored
- 137Recruiting or not yet
- November 2, 2026Latest posted
Newest trials
The newest 100 of 176, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.
| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
|---|---|---|---|---|---|---|---|---|---|
| November 2, 2026 | NCT07909460 | Blood Brain Barrier Dysfunction in Glioma and Epileptogenesis | University College, London | Observational | Not yet recruiting | Epilepsy, Glioma | 56 | clinicaltrials.gov | |
| October 22, 2026 | NCT07890038 | The Clinical Application Value of CAIX-Targeted PET Hypoxia Imaging in Malignant Tumors | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Observational | Active not recruiting | Nasopharyngeal Cancers, Lung Cancer (NSCLC), Esophageal Cancer, Glioma | 50 | China | clinicaltrials.gov |
| October 22, 2026 | NCT07888647 | IDH1-vac in Patients With Newly Diagnosed IDH1R132H-positive High-grade Astrocytomas | German Cancer Research Center | Phase 2 | Not yet recruiting | Astrocytoma, IDH-Mutant, Grade 3, Astrocytoma, IDH-Mutant, Grade 4 | 216 | Germany | clinicaltrials.gov |
| October 9, 2026 | NCT07867886 | An Optimization Study Evaluating Safety and Efficacy of the Y-90 Glioblastoma (GBM) Device in Patients With Recurrent GBM | Boston Scientific Corporation | Not applicable | Not yet recruiting | Recurrent Glioblastoma | 30 | France, Germany, Netherlands, Spain | clinicaltrials.gov |
| October 5, 2026 | NCT07859059 | Metronomic Temozolomide With Dexbrompheniramine for Recurrent High-Grade Glioma/Glioblastoma | University of Nebraska | Phase 1/2 | Not yet recruiting | High Grade Glioma, Glioblastoma, Gliosarcoma | 41 | United States | clinicaltrials.gov |
| September 22, 2026 | NCT07832734 | Metabolomics and Transcriptomics of Low- and High-Grade Gliomas | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | Observational | Recruiting | IDH Wildtype Glioblastoma, IDH Mutant Lower-Grade Gliomas | 220 | Italy | clinicaltrials.gov |
| September 21, 2026 | NCT07832123 | Safusidenib for Patients With Newly Diagnosed IDH1-mutant CNS WHO Grade 3 Oligodendroglioma and Astrocytoma - a Single Arm Phase II Study | University of Zurich | Phase 2 | Not yet recruiting | Glioma : Oligodendroglioma or Astrocytoma | 20 | Switzerland | clinicaltrials.gov |
| September 18, 2026 | NCT07826949 | A Study of SRN-101 Administered Prior to Surgical Resection in Adults With Recurrent High-Grade Glioma. | Nicholas Butowski | Phase 1 | Not yet recruiting | Recurrent High-Grade Gliomas, Brain Neoplasm, Glioma | 6 | United States | clinicaltrials.gov |
| September 15, 2026 | NCT07821112 | Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile® | University of California, Irvine | Phase 2 | Not yet recruiting | Glioma, Glioblastoma, GBM, Glioma, Malignant, Astrocytoma, Oligodendroglioma, Elderly Glioblastoma, Elderly GBM | 20 | United States | clinicaltrials.gov |
| September 11, 2026 | NCT07814872 | A Preregistered Multi-Cohort Evaluation of the FATHOM AI System for Molecular Testing Prioritization to Support Clinical Trial Enrollment | Harvard Medical School (HMS and HSDM) | Observational | Not yet recruiting | Neoplasms (Cancer / Tumors), Colorectal Neoplasms, Lung Neoplasms, Endometrial Neoplasms, Breast Neoplasms, Pancreatic... | 30,000 | United States | clinicaltrials.gov |
| September 10, 2026 | NCT07813741 | Susceptibility-Weighted Imaging in Preoperative Grading of Cerebral Gliomas | Assiut University | Observational | Not yet recruiting | Glioma, Brain Neoplasms, Cerebral Glioma | 90 | clinicaltrials.gov | |
| September 10, 2026 | NCT07813377 | Usefulness of Thromboelastography as a Predictor of Prognosis in Patients Undergoing Surgery for Glial Tumors and of the Risk of... | Fundacion Clinic per a la Recerca Biomédica | Observational | Recruiting | Glial Tumors, Thrombosis, Pulmonary Embolism (Diagnosis) | 100 | Spain | clinicaltrials.gov |
| August 27, 2026 | NCT07791264 | FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma | City of Hope Medical Center | Phase 1 | Not yet recruiting | Glioblastoma, Malignant Glioma, Recurrent Glioblastoma, Recurrent Malignant Glioma | 24 | United States | clinicaltrials.gov |
| August 26, 2026 | NCT07788677 | Tarlatamab Treatment Before and After Surgery in Surgically Resectable Recurrent High-grade Glioma: a Window of Opportunity Study... | Vall d'Hebron Institute of Oncology | Phase 1 | Not yet recruiting | High-Grade Glioma (HGG) | 10 | Spain | clinicaltrials.gov |
| August 25, 2026 | NCT07784985 | A Study of NST-628 in Recurrent Grade 4 Glioma | Nader Sanai | Early phase 1 | Not yet recruiting | Glioma, Recurrent High Grade, Grade 4 Malignant Glioma | 12 | United States | clinicaltrials.gov |
| August 24, 2026 | NCT07781852 | Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer | Lumina Pharmaceuticals Inc | Early phase 1 | Not yet recruiting | Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer, Colorectal Cancer, Esophageal Cancer, Gastric Cancer (GC)... | 40 | United States | clinicaltrials.gov |
| August 21, 2026 | NCT07778979 | Multiparametric Metabolic and Hypoxic PET/MRI Imaging Substudy in Gliomas | University of Alabama at Birmingham | Early phase 1 | Not yet recruiting | Glioma | 20 | United States | clinicaltrials.gov |
| August 10, 2026 | NCT07754734 | STUPP Regimen With or Without Lenvatinib for Newly Diagnosed Glioblastoma With MGMT Promoter Methylation | Dongguan People's Hospital | Phase 2 | Not yet recruiting | Glioma, Glioblastoma (GBM), MGMT-Methylated Glioblastoma | 138 | clinicaltrials.gov | |
| August 7, 2026 | NCT07751744 | Phase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal... | Jubilant Therapeutics Inc. | Phase 1/2 | Not yet recruiting | Brain Metastases From Solid Tumors, Leptomeningeal Disease, High Grade Glioma (HGG), Glioblastoma (GBM) | 113 | clinicaltrials.gov | |
| August 6, 2026 | NCT07750457 | Proton vs. Photon Radiotherapy for Patients With WHO Grade 2-3 Glioma | University Hospital, Essen | Not applicable | Recruiting | Glioma | 80 | Germany | clinicaltrials.gov |
| July 29, 2026 | NCT07733674 | Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma... | Radiomedix, Inc. | Phase 1 | Recruiting | Glioblastoma Multiforme (GBM), Pancreatic Ductal Adenocarcinoma (PDAC) | 20 | United States | clinicaltrials.gov |
| July 28, 2026 | NCT07731555 | Characterization of the Blood-Brain Barrier in High-Grade Glioma Through Immunohistochemical, Transcriptional, Fluorescein and Radiological... | Patrick Morris | Not applicable | Recruiting | Glioblastoma | 100 | Ireland | clinicaltrials.gov |
| July 24, 2026 | NCT07725640 | Feasibility Assessment of a Medical Device for Tumour Cell Retention and Radiotherapy Sensitization in Patients With Suspected High-grade... | Batea Oncology | Not applicable | Not yet recruiting | Glioma, High-Grade Glioma (HGG), Surgical Resection | 15 | Spain | clinicaltrials.gov |
| July 21, 2026 | NCT07717827 | Connectome-guided Onco-functional Resection With Tractography-Extended Neuronavigation in Brain Tumor Surgery | ARNAS Civico Di Cristina Benfratelli Hospital | Observational | Recruiting | Brain (Nervous System) Cancers, Glioma, Brain Metastasases, Brain Connectivity | 400 | Italy | clinicaltrials.gov |
| July 17, 2026 | NCT07710690 | A Clinical Trial Evaluating the Tolerability, Safety, and Preliminary Efficacy of NRG-103 Injection in Patients With Recurrent or... | Neuregen Therapeutics Co., Ltd. | Phase 1 | Recruiting | HGG, High Grade Glioma (III or IV), High Grade Glioma | 24 | China | clinicaltrials.gov |
| July 16, 2026 | NCT07707973 | Nimotuzumab Combined With the Stupp Regimen for Postoperative Residual Glioblastoma | Tianjin First Central Hospital | Phase 2 | Not yet recruiting | Glioma, Malignant | 50 | clinicaltrials.gov | |
| July 14, 2026 | NCT07703761 | AI-driven Processing and Analysis of Glioma Imaging Data | Università degli Studi di Trento | Observational | Recruiting | Glioma, Glioma (Diagnosis) | 700 | Italy | clinicaltrials.gov |
| July 14, 2026 | NCT07703605 | AI-Assisted MRI Molecular Subtyping in Pediatric Brain Tumors | Huashan Hospital | Observational | Not yet recruiting | Pediatric Brain Tumors, Glioma, Medulloblastoma, Ependymoma, Craniopharyngioma, Choroid Plexus Tumors | 1,400 | clinicaltrials.gov | |
| July 14, 2026 | NCT07703436 | Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive... | Nuvation Bio Inc. | Phase 2 | Recruiting | Grade 2 IDH1-mutant Glioma, Grade 3 IDH1-mutant Glioma, Glioma, IDH1-mutant Glioma, Oligodendroglioma... | 40 | United States | clinicaltrials.gov |
| July 13, 2026 | NCT07699172 | EEG-Guided Cognitive Function Preservation in Patients With Brain Tumors | Bo Wang | Not applicable | Not yet recruiting | Glioma, Brain Neoplasm, Brain Tumor Adult | 10 | China | clinicaltrials.gov |
| July 13, 2026 | NCT07698457 | Clinical Benefit of 18F-FET in Glioma. | Primo Biotechnology Co., Ltd | Phase 3 | Not yet recruiting | Glioma, 18F-Fluoroethyl-l-tyrosine | 36 | Taiwan | clinicaltrials.gov |
| July 7, 2026 | NCT07687277 | 3D-ASL and TDD-MRI for True Progression and Pseudoprogression After Glioma Surgery | Lanzhou University Second Hospital | Observational | Active not recruiting | Glioma, Brain Neoplasms | 75 | China | clinicaltrials.gov |
| July 1, 2026 | NCT07678684 | A Study of HF1K16 Combined With Bevacizumab in Patients With Recurrent or Progressive Glioma | HighField Biopharmaceuticals Corporation | Phase 2 | Recruiting | Glioma, Adult | 30 | China | clinicaltrials.gov |
| June 30, 2026 | NCT07675070 | Safety and Effectiveness Evaluation of Temozolomide (Amitzo, NanoAlvand) in Patients With Grade III and IV Glioma Tumors | NanoAlvand | Observational | Recruiting | Brain Tumor, Grade III Glioma, Grade IV Glioma | 100 | Iran | clinicaltrials.gov |
| June 29, 2026 | NCT07673705 | GliomaAI-Oligo: MRI-Based Detection of IDH Mutant Oligodendroglioma | Deep Learning Institute of Radiological Sciences | Observational | Completed | Glioma, Glioma (Diagnosis), Oligodendroglioma, 1p19q Codeletion, IDH-mutant Glioma (Oligodendroglioma, Astrocytoma) | 1,372 | India | clinicaltrials.gov |
| June 29, 2026 | NCT07673692 | GliomaAI-GBM: MRI-Based Detection of IDH Wildtype Glioblastoma | Deep Learning Institute of Radiological Sciences | Observational | Completed | Glioma, Glioma (Diagnosis), Glioblastom WHO Grade 4, IDH Wildtype Glioblastoma | 1,372 | India | clinicaltrials.gov |
| June 29, 2026 | NCT07673679 | GliomaAI-Astro4: MRI-Based Detection of IDH Mutant Astrocytoma Grade 4 | Deep Learning Institute of Radiological Sciences | Observational | Completed | Glioma, Glioma (Diagnosis), Astrocytoma, Astrocytoma, Grade IV, Astrocytoma, IDH-Mutant, Grade 4 | 1,372 | India | clinicaltrials.gov |
| June 29, 2026 | NCT07673666 | GliomaAI-Astro23: MRI-Based Detection of IDH Mutant Astrocytoma (Grade 2 and 3) | Deep Learning Institute of Radiological Sciences | Observational | Completed | Glioma, Glioma (Diagnosis), Astrocytoma, Astrocytoma of Brain, Astrocytoma, Grade II, Astrocytoma, IDH-Mutant, Grade 2... | 1,372 | India | clinicaltrials.gov |
| June 24, 2026 | NCT07664254 | GliomaAI-MG: MRI-Based Detection of Molecular Glioblastoma | Deep Learning Institute of Radiological Sciences | Observational | Completed | Glioma, Glioma (Diagnosis), Glioblastom WHO Grade 4 | 1,372 | India | clinicaltrials.gov |
| June 24, 2026 | NCT07664176 | NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors | Children's National Research Institute | Phase 1 | Recruiting | Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma, High Grade Gliomas, Medulloblastoma Recurrent, Ependymoma... | 30 | United States | clinicaltrials.gov |
| June 16, 2026 | NCT07650994 | Movie-Watching Functional MRI for Mapping Brain Function in Neurosurgical Patients | Brigham and Women's Hospital | Not applicable | Not yet recruiting | Glioma, Brain Tumor Adult | 90 | United States | clinicaltrials.gov |
| June 12, 2026 | NCT07644312 | Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG | Nationwide Children's Hospital | Phase 2 | Not yet recruiting | High Grade Glioma, Diffuse Intrinsic Pontine Glioma, WHO Grade 3 Glioma, WHO Grade 4 Glioma, Replication Repair... | 12 | clinicaltrials.gov | |
| June 10, 2026 | NCT07639970 | Evaluation of [⁶⁸Ga/¹⁷⁷Lu]HT547: Safety, Biodistribution, and Dosimetry in Solid Tumors | Hua Pang | Early phase 1 | Not yet recruiting | Breast Cancer, Head and Neck Cancer (H&N), Pancreatic Cancer, Glioma | 20 | clinicaltrials.gov | |
| June 9, 2026 | NCT07635173 | SM-1 Combined With Temozolomide in Subjects With Refractory or Recurrent High-Grade Gliomas | Shenzhen Zhenxing Medical Technology Co., Ltd | Phase 1 | Completed | Glioma, Glioblastomas (GBM), High Grade Gliomas | 35 | China | clinicaltrials.gov |
| June 8, 2026 | NCT07631338 | Low-grade Gliomas in Argentina: Incidence, Survival, and Therapeutic Strategies | Hospital Italiano de Buenos Aires | Observational | Recruiting | Low-grade Glioma | 40 | Argentina | clinicaltrials.gov |
| June 5, 2026 | NCT07629089 | VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations | Megan Mantica | Phase 1 | Not yet recruiting | Recurrent Glioma, IDH-mutant Gliomas | 36 | United States | clinicaltrials.gov |
| June 5, 2026 | NCT07628647 | Living Well With Brain Cancer: A Group-Based Intervention to Promote Whole-Person Well-Being | University of Colorado, Denver | Not applicable | Recruiting | Brain Cancer | 64 | United States | clinicaltrials.gov |
| June 5, 2026 | NCT07628634 | Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors | University of California, Irvine | Early phase 1 | Recruiting | Adenocarcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma, Transitional Cell Carcinoma, Ductal Carcinoma... | 25 | United States | clinicaltrials.gov |
| June 1, 2026 | NCT07616726 | Exploration and Characterization Ofintratumoral Electrophysiological Heterogeneity in Gliomas Using Magnetoencephalography | Hospices Civils de Lyon | Not applicable | Not yet recruiting | Patients Diagnosed With a Malignant Glioma | 60 | France | clinicaltrials.gov |
| May 29, 2026 | NCT07612917 | Brain Connectivity Changes in Glioma Patients During Treatment | Johannes Kepler University of Linz | Observational | Recruiting | Glioma (Any Grade) in the Brain, Gliomas, Malignant, fMRI Research, Neurocognitive Function | 20 | Austria | clinicaltrials.gov |
| May 27, 2026 | NCT07609472 | FG001 Near-Infrared Fluorescence Imaging During Tumor Resection in Newly Diagnosed High-Grade Glioma | FluoGuide A/S | Phase 2 | Not yet recruiting | High-Grade Glioma (WHO III-IV) | 76 | United States | clinicaltrials.gov |
| May 27, 2026 | NCT07608003 | Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis: | Xiangya Hospital of Central South University | Observational | Recruiting | Gliomas Harboring IDH1 and/or IDH2 Mutations, Glioma Glioblastoma Multiforme, Glioma of Brainstem, Glioma, Diffuse... | 500 | China | clinicaltrials.gov |
| May 20, 2026 | NCT07599371 | A Prospective, Single-arm Clinical Study on the Safety and Efficacy of Ivoximab Combined With Temozolomide in the Treatment of... | The First Affiliated Hospital of Zhengzhou University | Phase 1/2 | Recruiting | Relapsed/Refractory Glioma | 29 | China | clinicaltrials.gov |
| May 5, 2026 | NCT07567469 | A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressive High-Grade Glioma... | Regeneron Pharmaceuticals | Phase 1/2 | Not yet recruiting | High-Grade Glioma (HGG), Posterior Fossa-A Ependymoma | 120 | clinicaltrials.gov | |
| May 5, 2026 | NCT07567196 | PET-Guided Resection in High-Grade Gliomas | Universita degli Studi di Genova | Observational | Recruiting | Glioma Glioblastoma Multiforme, Glioma, High Grade, Glioma Surgery, Positron-Emission Tomography(PET) | 100 | Italy | clinicaltrials.gov |
| April 28, 2026 | NCT07553520 | Dietary Cysteine and Methionine Deprivation (CMD) in Glioma Patients | UNC Lineberger Comprehensive Cancer Center | Not applicable | Withdrawn | Glioblastoma Multiforme, Recurrent Glioma | 0 | United States | clinicaltrials.gov |
| April 24, 2026 | NCT07551336 | Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma | Beijing Biotech | Phase 1 | Recruiting | Malignant Glioma, High-Grade Gliomas, Glioblastoma, Recurrent High-Grade Gliomas, Recurrent Glioblastoma | 36 | China | clinicaltrials.gov |
| April 23, 2026 | NCT07547163 | Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | Observational | Recruiting | Glioma, Glioma of Brain, Low Grade Glioma of Brain, Low Grade Gliomas, IDH Mutation | 90 | Italy | clinicaltrials.gov |
| April 21, 2026 | NCT07542158 | Ultralow Dose PET Imaging of 18F-FDOPA | Akiva Mintz | Phase 2 | Enrolling by invitation | Heathy Volunteer, Parkinsonian Syndromes, Neuroendocrine (NE) Tumors, Gliomas | 200 | United States | clinicaltrials.gov |
| April 21, 2026 | NCT07541781 | Sitagliptin in Recurrent/Progressive Grade 4 Glioma | Kailin Yang, MD, PhD | Phase 1 | Recruiting | Glioma, Glioblastoma, Recurrent Glioma, Recurrent Glioblastoma, Grade 4 Malignant Glioma of Brain (Disorder) | 45 | United States | clinicaltrials.gov |
| April 20, 2026 | NCT07539441 | A Study of Mirdametinib in People With Central Nervous System Tumors | Memorial Sloan Kettering Cancer Center | Phase 1/2 | Recruiting | Central Nervous System Tumors, Glioma | 26 | United States | clinicaltrials.gov |
| April 15, 2026 | NCT07532031 | APT-weighted and Diffusion MRI for Characterizing Tumor Infiltration in High-Grade Gliomas | IRCCS Ospedale San Raffaele | Observational | Not yet recruiting | High-Grade Glioma, Glioblastoma, Brain Tumor Adult | 20 | clinicaltrials.gov | |
| April 13, 2026 | NCT07521657 | Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma | University of Alabama at Birmingham | Phase 2 | Not yet recruiting | Neurofibromatosis 1 (NF1) | 55 | United States | clinicaltrials.gov |
| March 30, 2026 | NCT07499141 | Use of Fluorescence in Gliomas | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | Observational | Completed | High Grade Glioma, Glioblastoma, Brain Neoplasms | 41 | Italy | clinicaltrials.gov |
| March 23, 2026 | NCT07488780 | Language Network Prehab Via fMRI Neurofeedback | Yale University | Not applicable | Recruiting | Glioma, Glioma Surgery | 4 | United States | clinicaltrials.gov |
| March 23, 2026 | NCT07488754 | Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) In Newly Diagnosed Glioma (WHO G3-G4) | Medical University of Warsaw | Not applicable | Recruiting | Glioblastoma, High-Grade Glioma (WHO III-IV), Glioblastoma (GBM) | 35 | Poland | clinicaltrials.gov |
| March 20, 2026 | NCT07486713 | Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies | Rigel Pharmaceuticals | Phase 4 | Recruiting | AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma, Solid Tumor Malignancies | 16 | United States | clinicaltrials.gov |
| March 19, 2026 | NCT07481721 | IL13Rα2 CAR-T Cells Secreting Anti-PD-L1 Antibody for Recurrent Malignant Glioma | Ming Yang | Phase 1 | Not yet recruiting | Recurrent Malignant Glioma | 24 | China | clinicaltrials.gov |
| March 18, 2026 | NCT07480941 | Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma | Beijing Biotech | Phase 1 | Recruiting | Glioblastoma, High-grade Glioma, Malignant Glioma, Recurrent Glioblastoma, Recurrent High-grade Glioma | 36 | China | clinicaltrials.gov |
| March 16, 2026 | NCT07475390 | 99mTc-1-thio-D-glucose SPECT/CT Versus 18F-Fluoroethyl-l-tyrosine PET/CT in Brain Tumor Imaging | Tomsk National Research Medical Center of the Russian Academy of Sciences | Not applicable | Active not recruiting | Glioma (Any Grade) in the Brain | 40 | Russia | clinicaltrials.gov |
| March 16, 2026 | NCT07472790 | A Study on the Novel Oncolytic Virus Combined With PD-1 Inhibitor in the Treatment of Recurrent High-grade Glioma | Beijing Bio-Targeting Therapeutics Technology Co., Ltd | Phase 1 | Not yet recruiting | High-grade Glioma | 15 | China | clinicaltrials.gov |
| March 13, 2026 | NCT07471100 | Neuromodulation-Induced Cortical Prehabilitation in High Grade Glioma Near the Motor Pathway: Cortical Plasticity Assessed by Navigated... | Azienda Sanitaria dell'Alto Adige | Not applicable | Not yet recruiting | Brain Tumor Adult, Glioma, Glioma, High Grade | 63 | clinicaltrials.gov | |
| March 13, 2026 | NCT07469735 | Vorasidenib Guided by AGX PET in Recurrent/Low-grade Glioma | Huashan Hospital | Not applicable | Not yet recruiting | Glioma, Diffuse Glioma, Recurrent Gliomas | 10 | China | clinicaltrials.gov |
| March 12, 2026 | NCT07468136 | Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas | Mayo Clinic | Phase 1/2 | Recruiting | Anaplastic Oligodendroglioma, Astrocytoma, IDH-Mutant, Grade 3, Astrocytoma, IDH-Mutant, Grade 4, Diffuse Astrocytoma... | 33 | United States | clinicaltrials.gov |
| March 12, 2026 | NCT07465796 | A First-in-Human Study of the CIPHER System During Brain Surgery for Newly Diagnosed Glioma | Coherence Neuro Australia Pty Limited | Not applicable | Recruiting | Glioma, Tumor, Electrocorticography, Brain | 10 | Australia | clinicaltrials.gov |
| March 11, 2026 | NCT07464925 | A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma | Tetragon Biosciences Ltd | Phase 1 | Recruiting | Glioblastoma Multiforme of Brain, Glioma, Glioblastoma | 30 | United States | clinicaltrials.gov |
| March 10, 2026 | NCT07462507 | Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1 | Washington University School of Medicine | Phase 2 | Recruiting | Central Nervous System Cancer, Brain Metastases | 104 | United States | clinicaltrials.gov |
| March 9, 2026 | NCT07457307 | Integrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-Linac | NYU Langone Health | Phase 1 | Not yet recruiting | High-grade Glioma | 20 | United States | clinicaltrials.gov |
| March 6, 2026 | NCT07455045 | A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG) | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | Phase 1 | Not yet recruiting | High Grade Glioma (III or IV), Diffuse Midline Glioma (DMG), Glioblastoma (GBM) | 40 | China | clinicaltrials.gov |
| March 5, 2026 | NCT07450872 | Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors | The Children's Hospital of Zhejiang University School of Medicine | Observational | Recruiting | Cancer, Glioma, Leukemia (Both ALL and AML) | 600 | China | clinicaltrials.gov |
| March 4, 2026 | NCT07448480 | Comprehensive Analysis of Chemotherapy and Targeted Therapy Outcomes in Recurrent Malignant Gliomas | Blokhin's Russian Cancer Research Center | Observational | Active not recruiting | Recurrent Malignant Glioma, Glioblastoma, Anaplastic Astrocytoma, Pleomorphic Xanthoastrocytoma | 1,000 | Russia | clinicaltrials.gov |
| March 3, 2026 | NCT07447531 | T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas | John M. Buatti | Not applicable | Recruiting | Malignant Glioma | 15 | United States | clinicaltrials.gov |
| February 27, 2026 | NCT07440290 | DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF... | Cancer Research UK | Phase 2/3 | Recruiting | Haematological Malignancy, Malignant Neoplasm, Lymphoproliferative Disorders, Neoplasms by Histologic Type, Neoplasms... | 30 | United Kingdom | clinicaltrials.gov |
| February 27, 2026 | NCT07439302 | Monitoring of Neurological Symptoms, Treatment Tolerance, and Quality of Life Using the Resilience PRO Electronic Patient-reported Outcome... | Assistance Publique - Hôpitaux de Paris | Not applicable | Not yet recruiting | Oncology, Glioma | 80 | France | clinicaltrials.gov |
| February 27, 2026 | NCT07439172 | Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma. | Cooper Norcross Health | Phase 2 | Recruiting | High Grade Gliomas, Glioblastoma, Astrocytoma, Oligodendroglioma | 70 | United States | clinicaltrials.gov |
| February 27, 2026 | NCT07438860 | Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG | Tiffany Hodges | Phase 1 | Not yet recruiting | Malignant Brain Tumors, Glioma | 12 | United States | clinicaltrials.gov |
| February 20, 2026 | NCT07424092 | Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors | Clinica Universidad de Navarra, Universidad de Navarra | Phase 2 | Recruiting | High Grade Glioma, Ependymoma, Embryonal Tumor of Brain, Recurrence, Refractory, Pediatric, Young Adult | 39 | Netherlands, Spain | clinicaltrials.gov |
| February 18, 2026 | NCT07416838 | Quality of Life and Cognitive Functioning in Patients With Glial Tumors | Institute of Oncology Ljubljana | Not applicable | Completed | Glial Tumors | 90 | Slovenia | clinicaltrials.gov |
| February 18, 2026 | NCT07416188 | Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1/2 | Recruiting | Recurrent Glioblastoma, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype, Relapsed Cancer, Recurrent Tumor... | 40 | United States | clinicaltrials.gov |
| February 17, 2026 | NCT07413796 | Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted... | Medical University of Warsaw | Not applicable | Recruiting | Brain Tumor Adult, Brain Tumor Benign, Meningioma, Glioma, Glioblastoma | 382 | Poland | clinicaltrials.gov |
| February 17, 2026 | NCT07411690 | Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors | Medical University of Warsaw | Observational | Recruiting | Brain Tumor Adult, Brain Tumor Benign, CerebroSpinal Fluid (CSF) Leak, Craniotomy, Glioblastoma, Glioma, Meningioma | 200 | Poland | clinicaltrials.gov |
| February 12, 2026 | NCT07405372 | Construction and Application of an IDH Mutation-Targeted PET/MRI Imaging Framework for Precision Diagnosis of Gliomas | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Observational | Recruiting | Glioma | 10 | China | clinicaltrials.gov |
| February 5, 2026 | NCT07389278 | Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG) | Sabine Mueller, MD, PhD | Phase 1/2 | Not yet recruiting | Glioblastoma, High-Grade Glioma (WHO III-IV), High-grade Glioma, Diffuse Midline Glioma, H3 K27M-Mutant, Diffuse... | 97 | United States | clinicaltrials.gov |
| January 30, 2026 | NCT07379463 | Amino Acid Transporter System PET/CT Imaging in AATS-Related Diseases | Tianjin Medical University | Observational | Recruiting | Amino-Acid Transport Disorder, Primary Hyperparathyroidism, Glioma | 500 | China | clinicaltrials.gov |
| January 29, 2026 | NCT07376304 | Intraoperative Ultrasound for Brain Tumor Surgery Enhanced by AI | Hospital del Rio Hortega | Phase 3 | Not yet recruiting | Brain Tumor Adult | 100 | clinicaltrials.gov | |
| January 29, 2026 | NCT07374692 | Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors | National Cancer Institute (NCI) | Observational | Completed | Recurrent CNS Tumors, Brain Cancer, Gliomas, IDH-wildtype Gliomas, IDH-mutant Gliomas, Rare CNS Tumor | 4 | United States | clinicaltrials.gov |
| January 26, 2026 | NCT07366892 | Leica Microsystems Sponsored PMCF Study to Collect and Confirm Clinical Data on the Performance of the GLOW400 Device When Used in... | Leica Microsystems (Schweiz) AG | Observational | Recruiting | Suspected Grade III and IV Gliomas Requiring Surgical Intervention, Neurosurgical Procedure, Glioma, Glioblastoma (GBM) | 37 | Portugal, Switzerland | clinicaltrials.gov |
| January 15, 2026 | NCT07343492 | fMRI Reveal Functional Preservation in Glioma Peritumoral Edema | West China Hospital | Observational | Completed | Glioma | 44 | China | clinicaltrials.gov |
| January 15, 2026 | NCT07342699 | Location-Molecular Integrated Outcomes in 450 Cerebellar Glioma Microsurgical Cases | West China Hospital | Observational | Completed | Gliomas | 450 | China | clinicaltrials.gov |
| January 14, 2026 | NCT07338539 | BIO-SHORT: Hypofractionated RT for Poor-Prognosis GBM | Tata Memorial Centre | Not applicable | Recruiting | Glioma | 108 | India | clinicaltrials.gov |
Sponsors posting most
| Sponsor | New trials | Latest |
|---|---|---|
| Deep Learning Institute of Radiological Sciences | 5 | June 29, 2026 |
| Mayo Clinic | 4 | March 12, 2026 |
| NYU Langone Health | 4 | March 9, 2026 |
| Tata Memorial Centre | 4 | January 14, 2026 |
| Nationwide Children's Hospital | 3 | June 12, 2026 |
| Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 3 | April 23, 2026 |
| Medical University of Warsaw | 3 | March 23, 2026 |
| West China Hospital | 3 | January 15, 2026 |
| University of Zurich | 2 | September 21, 2026 |
| University of California, Irvine | 2 | September 15, 2026 |
| University of Alabama at Birmingham | 2 | August 21, 2026 |
| Huashan Hospital | 2 | July 14, 2026 |
| University of Colorado, Denver | 2 | June 5, 2026 |
| Beijing Biotech | 2 | April 24, 2026 |
| Memorial Sloan Kettering Cancer Center | 2 | April 20, 2026 |
| Beijing Bio-Targeting Therapeutics Technology Co., Ltd | 2 | March 16, 2026 |
| Cancer Research UK | 2 | February 27, 2026 |
| Leica Microsystems (Schweiz) AG | 2 | January 26, 2026 |
| Second Affiliated Hospital, Zhejiang University, School of Medicine | 2 | December 29, 2025 |
| Telix Pharmaceuticals (Innovations) Pty Limited | 2 | November 20, 2025 |
By phase
| Phase | New trials | Latest |
|---|---|---|
| Observational | 50 | November 2, 2026 |
| Not applicable | 36 | October 9, 2026 |
| Phase 1 | 32 | September 18, 2026 |
| Phase 2 | 25 | October 22, 2026 |
| Phase 1/2 | 15 | October 5, 2026 |
| Early phase 1 | 11 | August 25, 2026 |
| Phase 3 | 4 | July 13, 2026 |
| Phase 2/3 | 2 | February 27, 2026 |
| Phase 4 | 1 | March 20, 2026 |
By country
| Country | New trials | Latest |
|---|---|---|
| United States | 57 | October 5, 2026 |
| China | 38 | October 22, 2026 |
| Italy | 10 | September 22, 2026 |
| Germany | 9 | October 22, 2026 |
| India | 9 | June 29, 2026 |
| France | 5 | October 9, 2026 |
| Netherlands | 5 | October 9, 2026 |
| Spain | 5 | October 9, 2026 |
| Switzerland | 4 | September 21, 2026 |
| Austria | 3 | May 29, 2026 |
| Poland | 3 | March 23, 2026 |
| Australia | 3 | March 12, 2026 |
| Iran | 2 | June 30, 2026 |
| Russia | 2 | March 16, 2026 |
| United Kingdom | 2 | February 27, 2026 |
| Canada | 2 | September 17, 2025 |
| Finland | 2 | December 18, 2024 |
| Ireland | 1 | July 28, 2026 |
| Taiwan | 1 | July 13, 2026 |
| Argentina | 1 | June 8, 2026 |
| Slovenia | 1 | February 18, 2026 |
| Portugal | 1 | January 26, 2026 |
| Greece | 1 | July 22, 2025 |
| New Zealand | 1 | February 21, 2025 |
| Belgium | 1 | January 28, 2025 |
Where the register publishes
U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.