Data / New clinical trials / Gastroesophageal Reflux

Gastroesophageal Reflux trials: 143 new since Nov 2024

Name: New Gastroesophageal Reflux clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Gastroesophageal Reflux clinical trials: 143 rows for $7.15, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 8 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/gastroesophageal-reflux, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 6, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

143 clinical studies in Gastroesophageal Reflux were first posted on ClinicalTrials.gov from November 12, 2024 to November 6, 2026; 32 have an industry sponsor and 87 are recruiting or about to. The newest, NCT07920679, was posted on November 6, 2026: Efficacy and Safety of K-CAB(Tegoprazan) 25 mg as Maintenance Therapy Following the Treatment of GERD (HK inno.N Corporation).

The request: Every new Gastroesophageal Reflux clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

143New trials
32Industry sponsored
87Recruiting or not yet
November 6, 2026Latest posted

Newest trials

The newest 100 of 143, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 6, 2026	NCT07920679	Efficacy and Safety of K-CAB(Tegoprazan) 25 mg as Maintenance Therapy Following the Treatment of GERD	HK inno.N Corporation	Observational	Recruiting	Maintenance Therapy Following Treatment for Gastroesophageal Reflux Disease(GERD)	12,868	South Korea	clinicaltrials.gov
November 5, 2026	NCT07919522	The Prospective Observational Study Evaluating the Clinical Profile and Correlation of Subjective and Objective Parameters of GERD in a...	Asian Institute of Gastroenterology, India	Observational	Completed	GERD	50	India	clinicaltrials.gov
November 2, 2026	NCT07910656	PDO Thread Embedding Plus Binh Vi Tablets for Gastroesophageal Reflux Disease	University of Medicine and Pharmacy at Ho Chi Minh City	Not applicable	Completed	Gastroesophageal Reflux Disease (GERD)	86	Vietnam	clinicaltrials.gov
October 29, 2026	NCT07902895	Intrathoracic Sleeve Migration (Sliding Hiatal Hernia) One Year or More After Laparoscopic Sleeve Gastrectomy	Kasr El Aini Hospital	Observational	Completed	Hiatal Hernia, Gastroesophageal Reflux Disease, Obesity, Postoperative Complications	61	Egypt	clinicaltrials.gov
October 26, 2026	NCT07893457	Effects of Tirzepatide on Esophagogastric Junction Mechanics, Reflux Burden, and Gastric Physiology in Adults With Obesity	Mayo Clinic	Phase 4	Not yet recruiting	Obese Adults	30	United States	clinicaltrials.gov
October 23, 2026	NCT07891455	Sedation Depth and EGJ Endoscopic Grading: A Randomized Controlled Trial	Mohamed Abd El-Raouf Tawfik	Not applicable	Completed	Gerd, Esophagogastric Junction, American Foregut Society Classification	192	Egypt	clinicaltrials.gov
October 9, 2026	NCT07868562	Gastroesophageal Reflux and Respiratory Function in Patients Undergoing Abdominoplasty	Universidade Federal de Pernambuco	Observational	Not yet recruiting	Abdominoplasty, Diaphragm, Respiratory Mechanics, Gastroesophageal Reflux Disease	30	Brazil	clinicaltrials.gov
October 2, 2026	NCT07854613	De Novo Gastroesophageal Reflux Disease After Sleeve Gastrectomy With and Without Omentopexy	China-Japan Friendship Hospital	Not applicable	Not yet recruiting	Omentopexy, Sleeve Gastrectomy, Gastroesophageal Reflux Disease	140	China	clinicaltrials.gov
October 1, 2026	NCT07852676	Effect of Bioflor on Gut Microbiota in Proton-Pump Inhibitor Users	Seoul National University Hospital	Phase 4	Completed	Dysbiosis, Gastroesophageal Reflux Disease (GERD)	80	South Korea	clinicaltrials.gov
October 1, 2026	NCT07850960	Effect of Omeprazole on Gut Microbiota in Adults With Obesity and GERD	Federal State Budgetary Scientific Institution	Phase 4	Not yet recruiting	Obesity & Overweight, Gastroesophageal Reflux Disease	26	Russia	clinicaltrials.gov
September 25, 2026	NCT07842354	Antireflux Mucosal Ablation vs Fundoplication for Refractory GERD	Minia University	Observational	Completed	Antireflux Mucosal Ablation, Laparoscopic Fundoplication Procedure, Refractory GERD, Endoscopic Therapy	200	Egypt	clinicaltrials.gov
September 17, 2026	NCT07826455	A Study to Evaluate Tegoprazan as a Diagnostic Tool for GERD	HK inno.N Corporation	Phase 4	Not yet recruiting	GERD (Gastroesophageal Reflux Disease)	100		clinicaltrials.gov
September 10, 2026	NCT07814027	POEM Versus Laparoscopic Heller Myotomy With Dor Fundoplication for Esophageal Achalasia	Minia University	Not applicable	Recruiting	Esophageal Achalasia, Esophageal Motility Disorders, Gastroesophageal Reflux	220	Egypt	clinicaltrials.gov
September 9, 2026	NCT07809620	Preoperative Predictors of Symptom Improvement After Laparoscopic Fundoplication	Minia University	Observational	Recruiting	Gastroesophageal Reflux Disease, Hiatal Hernia, Esophagitis, Peptic, Barrett Esophagus	470	Egypt	clinicaltrials.gov
September 1, 2026	NCT07797959	Thread-Embedding Acupuncture as an Adjunct to Proton Pump Inhibitor Therapy for Gastroesophageal Reflux Disease	University of Science Ho Chi Minh City	Not applicable	Recruiting	GERD, Gastroesophageal Reflux Disease	50	Vietnam	clinicaltrials.gov
August 31, 2026	NCT07795645	Validating a Medical AI Fine-Tuning Platform for Major Diseases	Beijing Friendship Hospital	Observational	Recruiting	Chronic Gastritis, Gastric Cancer (GC), Coronary Artery Disease, Stroke, Gastro Esophageal Reflux	96,000	China	clinicaltrials.gov
August 17, 2026	NCT07768202	AJYR+GV vs RYGB for GERD	Victor Dib Institute	Not applicable	Active not recruiting	Obesity, Morbid, Gastroesophageal Reflux (GERD)	60	Brazil	clinicaltrials.gov
August 11, 2026	NCT07757776	A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With...	Polares Medical SA	Not applicable	Not yet recruiting	Mitral Valve (MV) Regurgitation	20		clinicaltrials.gov
August 11, 2026	NCT07757698	A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With...	Polares Medical SA	Not applicable	Not yet recruiting	Mitral Valve (MV) Regurgitation	15		clinicaltrials.gov
August 11, 2026	NCT07757607	A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With...	Polares Medical SA	Not applicable	Not yet recruiting	Mitral Valve (MV) Regurgitation	20		clinicaltrials.gov
August 10, 2026	NCT07754721	Comprehensive Management Strategies for Gastroesophageal Reflux Disease: A Study of Multidimensional Interventions and Health Impacts	Hualien Tzu Chi General Hospital	Not applicable	Recruiting	Disorders of Gut-brain Interaction, Lifestyle and Dietary Interventions, Gastroesophageal Reflux Disease	220	Taiwan	clinicaltrials.gov
August 7, 2026	NCT07752407	A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With...	Phathom Pharmaceuticals, Inc.	Phase 3	Recruiting	Symptomatic Non-erosive Gastroesophageal Reflux Disease	500	United States	clinicaltrials.gov
August 6, 2026	NCT07750379	Assessing the Role of Proton Pump Inhibitors in Reducing Aspiration Incidence in Pediatric Laryngomalacia Cases	Minia University	Not applicable	Recruiting	Laryngomalacia	60	Egypt	clinicaltrials.gov
August 6, 2026	NCT07749989	A Retrospective Analysis of Patients With Gastroesophageal Reflux Disease Based on a Prospective Clinical Dataset	Beijing Friendship Hospital	Observational	Recruiting	Gastroesophageal Reflux Disease	5,000	China	clinicaltrials.gov
August 6, 2026	NCT07749352	One-year Clinical Outcomes of Endoscopic Cardia Banding Plication for Refractory Gastroesophageal Reflux Disease After Laparoscopic Sleeve...	China-Japan Friendship Hospital	Not applicable	Completed	Gastroesophageal Reflux Disease (GERD)	47	China	clinicaltrials.gov
August 4, 2026	NCT07744815	Mobile Application for Gastroesophageal Reflux Disease	Fooyin University	Not applicable	Completed	Gastroesophageal Reflux Esophagitis	90	Taiwan	clinicaltrials.gov
July 27, 2026	NCT07728682	Transit Bipartition After Sleeve Gastrectomy	Hospital das Clínicas de Ribeirão Preto	Not applicable	Not yet recruiting	Obesity & Overweight, Gastroesophageal Reflux (GERD), Weight Recurrence, Bariatric Surgery	40	Brazil	clinicaltrials.gov
July 24, 2026	NCT07726173	Transventricular Off-pump Mitral Valve Repair	Johns Hopkins University	Not applicable	Recruiting	Mitral Valve (MV) Regurgitation	175	United States	clinicaltrials.gov
July 23, 2026	NCT07722663	Endoscopic Classification of Fundoplication Integrity Predicts Pathologic Reflux	IRCCS Policlinico S. Donato	Observational	Completed	Gastro Esophageal Reflux	153	Italy	clinicaltrials.gov
July 22, 2026	NCT07718828	Laparoscopic Nissen Versus Toupet Fundoplication for Hiatal Hernia.	Sofia Med Hospital	Not applicable	Recruiting	Hiatal Hernia, Paraesophageal, Hiatal Hernia Large, Hiatal Hernia With Gastroesophageal Reflux Disease	200	Bulgaria	clinicaltrials.gov
July 21, 2026	NCT07716592	PROPER-GERD: A Prospective Crossover Study to Evaluate Probe Placement Optimization for Reflux Testing in Women and Lower-BMI Patients	University of Chicago	Not applicable	Not yet recruiting	GERD	80	United States	clinicaltrials.gov
July 17, 2026	NCT07712614	A Comparison of Cosmos Rx Medication Adherence Platform vs. Pharmacy Fill Adherence Measures	Cosmos Rx, Inc	Not applicable	Not yet recruiting	GERD (Gastroesophageal Reflux Disease)	50	United States	clinicaltrials.gov
July 17, 2026	NCT07711912	POLAR-STUDY: Polish AntiReflux Study	University of Warmia and Mazury in Olsztyn	Observational	Enrolling by invitation	Reflux Disease, Gastro-Esophageal	200	Poland	clinicaltrials.gov
July 16, 2026	NCT07707011	Potassium Competitive Acid Blocker (PCAB) Test-Guided vs Physiologic Test-Guided Treatment in Patients With Typical Reflux Symptoms	Mahidol University	Not applicable	Enrolling by invitation	GERD, Acid Reflux, Treatment	120	Thailand	clinicaltrials.gov
July 15, 2026	NCT07705425	EPX-HTG for Structural Heart Procedures	EchoPixel, Inc.	Not applicable	Not yet recruiting	Atrial Fibrillation (AF), Mitral Valve (MV) Regurgitation	20	United States	clinicaltrials.gov
July 14, 2026	NCT07700342	QUality of Sleep Improvement With Evening Topical Therapy for Non-Erosive Gastroesophageal Reflux Disease (The QUIET Trial)	Cellmedis	Not applicable	Recruiting	Nocturnal Symptoms of GERD, Sleep Disorders in GERD, GERD (Gastroesophageal Reflux Disease), Non-Erosive...	50	Poland	clinicaltrials.gov
July 1, 2026	NCT07678177	An Observational Study to Evaluate the Efficacy and Safety of K-CAB Tab./K-CAB ODT(Tegoprazan) in GERD Patients	HK inno.N Corporation	Observational	Recruiting	GERD (Gastroesophageal Reflux Disease)	5,384	South Korea	clinicaltrials.gov
June 25, 2026	NCT07667894	Mindfulness Intervention for Emotional Distress (MIED) in Patients With GERD	Xinghua Liu	Not applicable	Recruiting	Gastroesophageal Reflux Disease, Emotional Distress	500	China	clinicaltrials.gov
June 22, 2026	NCT07659080	Antireflux Surgery Without Preoperative Esophageal Manometry	McMaster University	Not applicable	Not yet recruiting	GERD, Hiatal Hernia, Heartburn, Paraesophageal Hernia, Gastroesophageal Reflux	96	Canada, United States	clinicaltrials.gov
June 12, 2026	NCT07643779	Symptom Severity, Posture, Pain, and Physical Activity in Gastroesophageal Reflux Disease	Karabuk University	Observational	Recruiting	Gastroesophageal Reflux Disease (GERD), Symptom, Musculoskeletal Pain, Physical Activity	51	Turkey (Türkiye)	clinicaltrials.gov
June 10, 2026	NCT07638423	Endoscopic Injection of Autologous Fat-Derived Cells (SVF) for Adults With Refractory Gastroesophageal Reflux Disease (GERD). (The...	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	Not applicable	Not yet recruiting	GERD (Gastroesophageal Reflux Disease)	15		clinicaltrials.gov
June 9, 2026	NCT07634614	Pre- and Post-Therapy Evaluation of Air-Associated Symptoms in Patients With Gastro-esophageal Reflux Disease (GERD): Assessing the Role of...	Prof Urs Zingg	Observational	Enrolling by invitation	GERD	100	Switzerland	clinicaltrials.gov
June 3, 2026	NCT07624383	New Topical tReatment Options for Symptomatic patiEnts With Nonerosive gastroesophageaL Reflux dIsease (The RELIEF Trial)	Cellmedis	Not applicable	Recruiting	GERD (Gastroesophageal Reflux Disease), NERD, Heartburn, Regurgitation, Gastric	50	Poland	clinicaltrials.gov
June 2, 2026	NCT07620899	Biological Optimization Versus Standard Care in Post-POEM Achalasia Patients (BIO-POEM)	Asian Institute of Gastroenterology, India	Not applicable	Active not recruiting	Achalasia Cardia, GERD (Gastroesophageal Reflux Disease)	166	India	clinicaltrials.gov
May 26, 2026	NCT07607067	Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve Gastrectomy	Hospital de Mataró	Observational	Not yet recruiting	Reflux Disease, Gastro-Esophageal, Sleeve Gastrectomy, Saliva Collection, Reflux Esophagitis (RE), Barrett Esophagus	60		clinicaltrials.gov
May 20, 2026	NCT07600008	Development of a Preparation for Supportive Supplementation of Probiotics in Patients With Reflux	University Hospital Olomouc	Early phase 1	Recruiting	Reflux Disease, Microbiome, Probiotics Supplement	50	Czechia	clinicaltrials.gov
May 7, 2026	NCT07573852	ECG and CXR for Predicting Cardiovascular Diseases	Shanghai Zhongshan Hospital	Observational	Completed	Valvular Heart Diseases, Valvular Heart Disease Stenosis and Regurgitation, Regurgitation, Aortic Valve, Regurgitation...	116,380	China	clinicaltrials.gov
May 7, 2026	NCT07573280	Effects of Clinical Pilates Exercises on Symptoms, Posture, Balance and Quality of Life in GERD	Istinye University	Not applicable	Completed	Pilates Exercise, Gastro Esophageal Reflux	33	Turkey (Türkiye)	clinicaltrials.gov
May 4, 2026	NCT07563790	A Pre-market, Two-stages Interventional Clinical Investigation to Evaluate the Safety and the Performance of Fibroin Syrup in Reducing the...	Rose Pharma SA	Not applicable	Completed	GERD (Heartburn, Regurgitation, and Dyspepsia), Gastroesophageal Reflux (GERD)	47	Italy	clinicaltrials.gov
May 4, 2026	NCT07563491	Comparison of Esomeprazole Versus Vonoprazan in Gastroesophageal Reflux Disease	Muhammad Aamir Latif	Not applicable	Completed	Gastro Esophageal Reflux	824	Pakistan	clinicaltrials.gov
May 1, 2026	NCT07560787	Impact of Crural Repair and Gastropexy During Laparoscopic Sleeve Gastrectomy	Van Training and Research Hospital	Not applicable	Completed	Obesity, Morbid, Gastroesophageal Reflux Disease	50	Turkey (Türkiye)	clinicaltrials.gov
April 29, 2026	NCT07556289	Transoral Incisional Fundoplication (TIF) for Patients Suffering From Gastroesophageal Reflux Disease in an Asian Population	Chinese University of Hong Kong	Phase 2	Recruiting	Fundoplication, GERD	20	Hong Kong	clinicaltrials.gov
April 22, 2026	NCT07544433	Diaphragmatic Training on GERD	Changhua Christian Hospital	Not applicable	Recruiting	GERD, Diaphragmatic Training	42	Taiwan	clinicaltrials.gov
April 17, 2026	NCT07537244	Impact of GEA Simultaneous to VSG on Post-operative GERD	Clinica Gastrobese	Not applicable	Active not recruiting	Obesity, Reflux, Gastroesophageal	60	Brazil	clinicaltrials.gov
April 2, 2026	NCT07506746	PRospective Registry of Esophageal Motility	IRCCS San Raffaele	Observational	Recruiting	Esophageal Diseases, Achalasia, Eosinophilic Esophagitis, Motility Disorder, GERD	10,000	Italy	clinicaltrials.gov
April 1, 2026	NCT07506356	Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors	University Hospital, Geneva	Observational	Recruiting	Diabete Type 2, Regurgitation, Pulmonary Aspiration During Anaesthetic Induction	38	Switzerland	clinicaltrials.gov
March 19, 2026	NCT07482969	Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids)	University Hospital, Motol	Observational	Recruiting	Gastro Esophageal Reflux	1,000	Czechia	clinicaltrials.gov
March 4, 2026	NCT07449728	The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression	Pirogov Russian National Research Medical University	Not applicable	Recruiting	Varicose Veins, Chronic Venous Insufficiency	400	Russia	clinicaltrials.gov
February 27, 2026	NCT07437768	Vonoprazan Test for PPI Refractory GERD	Fu Jen Catholic University Hospital	Not applicable	Enrolling by invitation	Refractory GERD, NERD, PCAB	100	Taiwan	clinicaltrials.gov
February 19, 2026	NCT07421011	Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in...	Valenta Pharm JSC	Phase 1	Recruiting	Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia, Postcholecystectomy Syndrome	36	Russia	clinicaltrials.gov
February 9, 2026	NCT07395219	European TIF2.0 Registry	Cleveland Clinic London	Observational	Enrolling by invitation	Gastro -Oesophagal Reflux, Laryngo-pharyngeal Reflux	500	Austria, Italy, Serbia, Switzerland, Turkey (Türkiye), United Arab Emirates...	clinicaltrials.gov
February 2, 2026	NCT07380932	Catheter Ablation for AF in Patients With Severe Mitral Regurgitation After Successful Transcatheter Mitral-Valve Repair	Atrial Fibrillation Network	Not applicable	Not yet recruiting	Atrial Fibrillation (AF), Mitral Valve (MV) Regurgitation	956	Germany	clinicaltrials.gov
January 30, 2026	NCT07379645	A Clinical Trial of PepZinGI® for Acute Heartburn Relief and Sleep Outcomes	NutriScience Innovations, LLC	Not applicable	Completed	Heartburn	50	United States	clinicaltrials.gov
January 23, 2026	NCT07364838	Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult Volunteers	Daewon Pharmaceutical Co., Ltd.	Phase 1	Completed	GERD (Gastroesophageal Reflux Disease)	24	South Korea	clinicaltrials.gov
January 15, 2026	NCT07344935	Evaluation of the Effectiveness of the Ezisurg Stapling (Ezi Endo Lite) During Laparoscopic Nissen Sleeve Gastrectomy	Ezisurg Medical Co. Ltd.	Not applicable	Completed	Gastroesophageal Reflux Disease (GERD)	167	France	clinicaltrials.gov
January 13, 2026	NCT07338448	Electrical Acupoint Stimulation on Gastric Reflux During I-gel Ventilation	Air Force Military Medical University, China	Not applicable	Not yet recruiting	Anesthesia	116		clinicaltrials.gov
January 8, 2026	NCT07326904	Study Comparing Fexuprazan and Esomeprazole in Patients With Gastroesophageal Reflux Disease	Universitas Indonesia	Phase 3	Completed	Gastro Oesophageal Reflux Disease	145	Indonesia	clinicaltrials.gov
January 2, 2026	NCT07313774	A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Maintenance of Healing in Participants With Healed Erosive...	Cinclus Pharma Holding AB	Phase 3	Withdrawn	GERD (Gastroesophageal Reflux Disease)	0		clinicaltrials.gov
December 30, 2025	NCT07310927	Alginate vs Sucralfate for GERD Symptomatic Relief	CMH Lahore Medical College and Institute of Dentistry	Phase 2/3	Completed	GERD	140	Pakistan	clinicaltrials.gov
December 29, 2025	NCT07308041	A Study to Investigate the Effect of Linaprazan Glurate on the Pharmacokinetics of Amoxicillin	Cinclus Pharma Holding AB	Phase 1	Completed	Drug Interaction, GERD (Gastroesophageal Reflux Disease), Safety, and Tolerability	12	Sweden	clinicaltrials.gov
December 18, 2025	NCT07291700	Study on Hydrotalcite for Relief of Acid Symptoms Due to Acid Rebound After Stopping Long-Term PPI Therapy	Bayer	Observational	Recruiting	Gastroesophageal Reflux	167	Germany	clinicaltrials.gov
December 8, 2025	NCT07268820	Heartburn, Gastroesophageal Reflux Disease	Incheon St.Mary's Hospital	Phase 4	Recruiting	GERD	160	South Korea	clinicaltrials.gov
December 5, 2025	NCT07267117	Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease	Second Affiliated Hospital, Zhejiang University, School of Medicine	Observational	Recruiting	Heart Valve Disease, Mitral Valve (MV) Regurgitation, Mitral Valve Disease, Mitral Valve Stenosis, Aortic Valve...	10,000	China	clinicaltrials.gov
November 26, 2025	NCT07252180	Comparing Two Different Methods of Ablation of Inlet Patches (APC vs RFA)	Assaf-Harofeh Medical Center	Not applicable	Active not recruiting	GERD (Gastroesophageal Reflux Disease), Throat Disorders	72	Israel	clinicaltrials.gov
November 26, 2025	NCT07252115	TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease	Beijing Friendship Hospital	Not applicable	Recruiting	Hernia, Hiatal, GERD (Gastroesophageal Reflux Disease)	143	China	clinicaltrials.gov
November 26, 2025	NCT07251660	Comparison of Early Postoperative Outcomes Between Minimally Invasive Valve Surgery Via Right Thoracotomy and Conventional Valve Surgery...	Chaudhry Pervaiz Elahi Institute of Cardiology	Not applicable	Not yet recruiting	Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis, Aortic Valve Insufficiency, Valvular Heart Disease Stenosis...	32		clinicaltrials.gov
November 26, 2025	NCT07251010	Phrenoesophageal Ligament Reconstruction With Mesh	Clinical Trial Aseer	Not applicable	Recruiting	Hiatus Hernia, Gastreoesophageal Reflux Disease	60	Saudi Arabia	clinicaltrials.gov
November 21, 2025	NCT07243197	DragonFly M2 Pivotal Study	Hangzhou Valgen Medtech Co., Ltd	Not applicable	Not yet recruiting	Mitral Valve (MV) Regurgitation	53	China	clinicaltrials.gov
November 12, 2025	NCT07227506	Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:	Medical College of Wisconsin	Observational	Recruiting	Gerd, Eosinophilic Esophagitis	50	United States	clinicaltrials.gov
September 30, 2025	NCT07199582	Association Between Obesity and Gastroesophageal Reflux Disease	Assiut University	Observational	Not yet recruiting	Gastro Esophageal Reflux, Obesity (Disorder)	200		clinicaltrials.gov
September 17, 2025	NCT07179250	Effect of Breathing Training on Symptoms of Gastroesophageal Reflux Disease	Changhua Christian Hospital	Not applicable	Not yet recruiting	Incentive Spirometer, Diaphragmatic Breathing, Gastroesophageal Reflux Disease (GERD), Breath Exercise	51		clinicaltrials.gov
September 17, 2025	NCT07178821	Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD	University of California, Irvine	Not applicable	Not yet recruiting	Achalasia, Esophageal, GERD (Gastroesophageal Reflux Disease)	120	United States	clinicaltrials.gov
September 16, 2025	NCT07176221	Endoscopic Cardial Constriction Ligation (ECCL) for Refractory GERD Using a Disposable Endoscope	Ying Zhu	Not applicable	Not yet recruiting	Gastroesophageal Reflux Disease (GERD)	46	China	clinicaltrials.gov
September 16, 2025	NCT07174882	Evaluation of the Clinical Course of NERD and Assessment of the Esophageal Mucosa Resistance	I.M. Sechenov First Moscow State Medical University	Observational	Active not recruiting	Non-Erosive Gastro-Esophageal Reflux Disease, Gastroesophageal Reflux Disease (GERD)	60	Russia	clinicaltrials.gov
September 5, 2025	NCT07158008	Comparison of Nissen-Sleeve and Gastric Bypass for GERD in Obese Patients	Jagiellonian University	Not applicable	Recruiting	Gastro Esophageal Reflux, Severe Obesity, Bariatric Surgery	560	Poland	clinicaltrials.gov
August 29, 2025	NCT07148583	BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months	Haiphong University of Medicine and Pharmacy	Not applicable	Recruiting	Infantile Colic, Gastroesophageal Reflux (GER), Functional Constipation, Functional Diarrhea, Dysbiosis	110	Vietnam	clinicaltrials.gov
August 29, 2025	NCT07148492	Antireflux Suture In One Anastomsis Gastric Bypass	Khyber Teaching Hospital	Not applicable	Recruiting	Reflux Disease, Gastro-Esophageal, Vomiting, Postoperative	316	Pakistan	clinicaltrials.gov
August 20, 2025	NCT07131397	The Effect of Inspiratory Muscle Training in People With Gastroesophageal Reflux Disease	University of West Attica	Not applicable	Recruiting	Gastro Esophageal Reflux	30	Greece	clinicaltrials.gov
August 17, 2025	NCT07127276	Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of Smartphone Application GERDCare	Institute of Gastroenterology and Hepatology, Vietnam	Not applicable	Not yet recruiting	GERD (Gastroesophageal Reflux Disease)	380	Vietnam	clinicaltrials.gov
August 15, 2025	NCT07125638	Long-term Follow-up After OAGB	Azienda Sanitaria Locale Napoli 2 Nord	Observational	Completed	Obesity, Morbid, Obesity, Abdominal, Ona Anastomosis Gastric Bypass, GERD, Bile Reflux Gastritis	2,368	Italy	clinicaltrials.gov
August 15, 2025	NCT07125521	Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare	Institute of Gastroenterology and Hepatology, Vietnam	Not applicable	Recruiting	GERD (Gastroesophageal Reflux Disease)	380	Vietnam	clinicaltrials.gov
August 14, 2025	NCT07121803	The Influence of Specialized Food Products Based on Ice-Cream on Esophageal Motility	Federal State Budgetary Scientific Institution	Not applicable	Recruiting	Ineffective Esophageal Motility, GERD (Gastroesophageal Reflux Disease)	30	Russia	clinicaltrials.gov
August 13, 2025	NCT07121062	Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue)	University Hospital Southampton NHS Foundation Trust	Observational	Not yet recruiting	Colic, Infantile, Milk Allergy, Cow's, Gastro Oesophageal Reflux Disease, Atopic Dermatitis (Eczema), Constipation...	350	United Kingdom	clinicaltrials.gov
August 7, 2025	NCT07108751	Association Between Gastroesophageal Reflux Disease (GERD) Severity and Dental Caries	Tanta University	Observational	Completed	Gastroesophageal Reflux Disease, Severity, Dental Caries	200	Egypt	clinicaltrials.gov
August 6, 2025	NCT07107672	Mass Balance Study of [14C]X842 in Healthy Adult Male Subjects	Jiangsu Sinorda Biomedicine Co., Ltd	Phase 1	Completed	Gastroesophageal Reflux Disease	6	China	clinicaltrials.gov
August 3, 2025	NCT07102329	BURDEN OF ESOPHAGEAL CANCER IN EOSINOPHILIC ESOPHAGITIS (ESCAPE STUDY)	IRCCS San Raffaele	Observational	Completed	Eosinophilic Esophagitis (EoE)	100,000	Italy	clinicaltrials.gov
August 1, 2025	NCT07099417	Screening of Valvular Heart Disease Using Single-channel Electrocardiogram	I.M. Sechenov First Moscow State Medical University	Observational	Recruiting	Valvular Heart Disease Stenosis and Regurgitation, Valvular Heart Disease	1,200	Russia	clinicaltrials.gov
July 30, 2025	NCT07093359	LINX vs Fundoplication	University of Oxford	Phase 3	Recruiting	Gastro-oesophageal Reflux Disease	460	United Kingdom	clinicaltrials.gov
July 17, 2025	NCT07070908	Modifications to Gastric Sleeve: Implications for GRED and Quality of Life	Hospital San Juan de Dios Tenerife	Not applicable	Active not recruiting	Obese Patients (BMI ≥ 30 kg/m²), Obese Patients, Obese Patients With Bariatric Surgery, Obese With Comorbidities	120	Spain	clinicaltrials.gov
July 17, 2025	NCT07069673	Abbott Cephea Mitral Valve Disease Registry	Abbott Medical Devices	Observational	Recruiting	Mitral Regurgitation, Mitral Stenosis, Mitral Valve Disease, Mitral Valve (MV) Regurgitation, Mitral Annulus...	1,000	United States	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Asian Institute of Gastroenterology, India	5	November 5, 2026
Minia University	4	September 25, 2026
Beijing Friendship Hospital	4	August 31, 2026
HK inno.N Corporation	3	November 6, 2026
Polares Medical SA	3	August 11, 2026
Hualien Tzu Chi General Hospital	3	August 10, 2026
Cinclus Pharma Holding AB	3	January 2, 2026
Universidade Federal de Pernambuco	2	October 9, 2026
China-Japan Friendship Hospital	2	October 2, 2026
Federal State Budgetary Scientific Institution	2	October 1, 2026
Cellmedis	2	July 14, 2026
Karabuk University	2	June 12, 2026
Changhua Christian Hospital	2	April 22, 2026
IRCCS San Raffaele	2	April 2, 2026
Medical College of Wisconsin	2	November 12, 2025
University of California, Irvine	2	September 17, 2025
I.M. Sechenov First Moscow State Medical University	2	September 16, 2025
Haiphong University of Medicine and Pharmacy	2	August 29, 2025
Institute of Gastroenterology and Hepatology, Vietnam	2	August 17, 2025
Implantica CE Reflux Ltd.	2	June 4, 2025

By phase

Phase	New trials	Latest
Not applicable	76	November 2, 2026
Observational	44	November 6, 2026
Phase 4	8	October 26, 2026
Phase 3	6	August 7, 2026
Phase 1	5	February 19, 2026
Phase 2	2	April 29, 2026
Early phase 1	1	May 20, 2026
Phase 2/3	1	December 30, 2025

By country

Country	New trials	Latest
United States	18	October 26, 2026
China	15	October 2, 2026
South Korea	10	November 6, 2026
Egypt	10	October 29, 2026
Italy	10	July 23, 2026
Vietnam	6	November 2, 2026
Brazil	6	October 9, 2026
Russia	6	October 1, 2026
Taiwan	6	August 10, 2026
Turkey (Türkiye)	6	June 12, 2026
India	5	November 5, 2026
Poland	5	July 17, 2026
Germany	5	February 2, 2026
Switzerland	4	June 9, 2026
United Kingdom	4	February 9, 2026
Czechia	3	May 20, 2026
Pakistan	3	May 4, 2026
Bulgaria	2	July 22, 2026
Thailand	2	July 16, 2026
Austria	2	February 9, 2026
Serbia	2	February 9, 2026
Spain	2	July 17, 2025
Canada	1	June 22, 2026
Hong Kong	1	April 29, 2026
United Arab Emirates	1	February 9, 2026

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.