New Frailty clinical trials: 345 posted since Nov 2024

Name: New Frailty clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Frailty clinical trials: 345 rows for $17.25, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 15 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (sponsor class, condition groups (MeSH), interventions, start date, enrollment type, location countries and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/frailty, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 6, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

345 clinical studies in frailty were first posted on ClinicalTrials.gov from November 13, 2024 to November 6, 2026; 13 have an industry sponsor and 220 are recruiting or about to. The newest, NCT07923188, was posted on November 6, 2026: Online Exercise Program for Transplant Patients: A Pilot Study (Cardenal Herrera University).

The request: Every new Frailty clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

345New trials
13Industry sponsored
220Recruiting or not yet
November 6, 2026Latest posted

Newest trials

The newest 100 of 345, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 6, 2026	NCT07923188	Online Exercise Program for Transplant Patients: A Pilot Study	Cardenal Herrera University	Not applicable	Enrolling by invitation	Kidney Transplantation, Physical Function, Muscle Weakness Condition, Physical Activity	20	Spain	clinicaltrials.gov
November 6, 2026	NCT07922499	Adapting an Evidence-Based Physical Activity Intervention to Prevent Frailty and Functional Decline in Older Women Living With HIV	University of Illinois Chicago	Not applicable	Not yet recruiting	Mobility Impairment, Frailty	210		clinicaltrials.gov
November 6, 2026	NCT07921758	The Role of Multidimensional Prognostic Index (MPI) in the Assessment of Elderly Patients underGoING Cardiac REHABilitation	Istituti Clinici Scientifici Maugeri SpA	Observational	Completed	Heart Failure, Acute Coronary Syndromes (ACS), Cardiac Surgery	202	Italy	clinicaltrials.gov
November 5, 2026	NCT07920575	Assessment of Transnational Performance of the Universal Cardiac Surgical Risk Score Across International Sites	Union Health System	Observational	Not yet recruiting	Heart Valve Diseases, Cardiac Surgical Procedures, Coronary Artery Disease	5,000		clinicaltrials.gov
November 4, 2026	NCT07916935	Eccentric Exercise in Community-dwelling Older Adults	The University of Northampton	Not applicable	Not yet recruiting	Ageing Well	30	United Kingdom	clinicaltrials.gov
November 4, 2026	NCT07916675	Preoperative Frailty and Suboptimal Mask Ventilation in Cardiac Surgery Patients	Ankara City Hospital Bilkent	Observational	Not yet recruiting	Frailty, Suboptimal Mask Ventilation	450	Turkey (Türkiye)	clinicaltrials.gov
November 4, 2026	NCT07914920	Postprandial Hypotension, Frailty and Post-Induction Hypotension in Older Patients Undergoing Noncardiac Surgery	Konya City Hospital	Observational	Not yet recruiting	Post-induction Hypotension (PIH), Postprandial Hypotension, Frailty	200	Turkey (Türkiye)	clinicaltrials.gov
October 29, 2026	NCT07903584	Personalized Drug Treatment of Frail Patients: Integrated Care and Real-Time Home Monitoring	Istituti Clinici Scientifici Maugeri SpA	Not applicable	Completed	Frailty, Polypharmacy (People Under Treatment With 5 or More Drugs), Multimorbidity	40	Italy	clinicaltrials.gov
October 28, 2026	NCT07902206	Creatine and Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation Plus Home-Based Exercise for Sarcopenia in Huntington's Disease	Universidad de Burgos	Not applicable	Not yet recruiting	Huntington Disease, Sarcopenia, Frailty	88	Spain	clinicaltrials.gov
October 27, 2026	NCT07898345	Prognostic Value of Functional-Nutritional Status in Older Adults With Acute Coronary Syndrome	Samara State Medical University	Observational	Not yet recruiting	Acute Coronary Syndromes (ACS)	270	Russia	clinicaltrials.gov
October 27, 2026	NCT07896876	Selenium, Sarcopenia, and Frailty in Hemodialysis	Ankara City Hospital Bilkent	Observational	Completed	Frailty, Sarcopenia, Selenium	78	Turkey (Türkiye)	clinicaltrials.gov
October 26, 2026	NCT07896174	Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery	Semmelweis University	Not applicable	Recruiting	Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications	480	Hungary	clinicaltrials.gov
October 26, 2026	NCT07893665	PROfiles of FGF-19 Post-prandial Secretion in Older Adults With Frailty and Without Frailty	Hospices Civils de Lyon	Not applicable	Not yet recruiting	Frailty, Sarcopenia	30	France	clinicaltrials.gov
October 23, 2026	NCT07892612	Frailty Training for Emergency Nurses: A Cluster RCT in Morocco	Cadi Ayyad University	Not applicable	Recruiting	Frail Elderly, Frailty	144	Morocco	clinicaltrials.gov
October 21, 2026	NCT07887334	Hypoglycemia Risk Assessment in Elderly and Senile Female Patients With Type 2 Diabetes Mellitus	Samara State Medical University	Observational	Completed	Type 2 Diabetes Mellitus, Hypoglycemia, Frailty, Sarcopenia	200	Russia	clinicaltrials.gov
October 21, 2026	NCT07886164	Whole-Body Point-of-Care Ultrasound in Older Adults Presenting to the Emergency Department After a Fall	Kocaeli City Hospital	Observational	Recruiting	Accidental Falls, Aged, Syncope	105	Turkey (Türkiye)	clinicaltrials.gov
October 19, 2026	NCT07880054	Sleep Quality and Frailty Among People Living With HIV	National Sun Yat-sen University	Observational	Completed	HIV Infections, Frailty, Sleep Quality, Oral Frailty	130	Taiwan	clinicaltrials.gov
October 14, 2026	NCT07872787	NURSE-led Geriatric Assessment in Older Colorectal Cancer Patients	Helse Stavanger HF	Not applicable	Not yet recruiting	Colo-rectal Cancer	50	Norway	clinicaltrials.gov
October 8, 2026	NCT07864831	Community-Based Multicomponent Exercise and Recreational Programme for Older Adults	Universidad de Murcia	Not applicable	Completed	Frailty, Aging, Physical Functional Performance, Postural Balance	184	Spain	clinicaltrials.gov
October 7, 2026	NCT07862933	AI-Based Conversational Social Support for Older Adults With Heart Failure	Chang Gung University of Science and Technology	Not applicable	Recruiting	Heart Failure	174	Taiwan	clinicaltrials.gov
October 6, 2026	NCT07861997	ENRICH Study: A Mixed-methods Feasibility Study of a Nurse-led Model of Care for Social Frailty in Philippine Primary Care	The Hong Kong Polytechnic University	Not applicable	Not yet recruiting	Frailty, Frailty in Older Adults, Frailty in Aging	30	Philippines	clinicaltrials.gov
October 6, 2026	NCT07860892	VOCALE: A Digital Intervention to Improve Quality of Life and Reduce Frailty Among Older Adults in Retirement Communities	University of Washington	Not applicable	Not yet recruiting	Frailty, Quality of Life	128		clinicaltrials.gov
October 5, 2026	NCT07857707	AI-Supported Physiotherapy After Hip Fracture in Frail Older Adults	Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal	Not applicable	Not yet recruiting	Hip Fractures, Frailty	48	Spain	clinicaltrials.gov
October 2, 2026	NCT07856602	Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)	Vinmec Research Institute of Stem Cell and Gene Technology	Phase 1	Not yet recruiting	Frailty Syndrome, Aging	20		clinicaltrials.gov
October 2, 2026	NCT07854275	Biomarkers, Abdominal Muscle, and Frailty in CKD	Ankara City Hospital Bilkent	Observational	Completed	Chronic Kidney Disease, Abdominal Muscles/Ultrasonography, Frailty	88	Turkey (Türkiye)	clinicaltrials.gov
October 1, 2026	NCT07851974	Patients With Long-stay at ICU: Factors and Evaluation - Feasibility Study	Uppsala University	Observational	Not yet recruiting	Frailty, Delirium Confusional State, Persistent Critical Illness, Post-Intensive Care Syndrome, Health-related Quality...	300	Sweden	clinicaltrials.gov
September 30, 2026	NCT07848802	Physical Function and Fall Risk in Older Adults in the Lalín Frailty Prevention Program	University of Vigo	Observational	Recruiting	Frailty, Fall Risk, Fall Prevention	56	Spain	clinicaltrials.gov
September 29, 2026	NCT07845656	A Home-based Multicomponent Exercise Intervention Program Based on the Fogg Behavior Model (FBM) for Older Adults With Osteosarcopenia and...	Jiawei Jiang	Not applicable	Recruiting	Osteosarcopenia; Frailty; Older Adults	70	China	clinicaltrials.gov
September 23, 2026	NCT07837505	Integrating Geriatric 8 (G8) Screening and Cancer and Age Research Group (CARG) Toxicity Assessment Score Into Routine Care for Older...	Assiut University	Observational	Not yet recruiting	Solid Neoplasms, Solid Tumors, Chemotherapy-Induced Toxicity	100		clinicaltrials.gov
September 23, 2026	NCT07837219	Frailty and Outcomes in Critically Ill Patients Receiving CRRT	Karolinska Institutet	Observational	Not yet recruiting	Acute Kidney Injury	22,000		clinicaltrials.gov
September 23, 2026	NCT07836465	A Pilot Study to Explore the Feasibility of Navigator and Coach Support for Community Participation by Older People	Bastiaan Van Grootven	Not applicable	Not yet recruiting	Frailty, Social Isolation in Older Adults, Frailty in Older Adults	45	Switzerland	clinicaltrials.gov
September 23, 2026	NCT07836127	Human Albumin Combined With Plasma Exchange for Frailty Intervention	Institute of Hematology & Blood Diseases Hospital, China	Not applicable	Not yet recruiting	Frailty, Plasma Exchange	34	China	clinicaltrials.gov
September 21, 2026	NCT07829484	VIVI-OLIVE: Multicomponent Exercise and Extra Virgin Olive Oil in Older Adults at High Risk of Falls	Fundacion Miguel Servet	Not applicable	Recruiting	Falls, Frailty	140	Spain	clinicaltrials.gov
September 18, 2026	NCT07829172	Immediate Effects of Vojta Therapy on Postural Control in Older Adults	Marianela Alejandra Valenzuela Sandoval	Not applicable	Completed	Postural Balance, Aging, Frailty	33	Chile	clinicaltrials.gov
September 18, 2026	NCT07828886	Immune Aging and Advanced Therapy Outcomes in Older Adults With IBD	First Affiliated Hospital, Sun Yat-Sen University	Observational	Not yet recruiting	Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Frailty, Immunosenescence	300		clinicaltrials.gov
September 18, 2026	NCT07828847	Involvement of Muscle Mitochondrial Dysfunction in Frailty in Older Adults. Role of Exercise	Fundación para la Investigación del Hospital Clínico de Valencia	Not applicable	Recruiting	Diabetes Type 2, Frail Elderly Syndrome, Mitochondrial Function, Bioenergetics, Functionality	120	Spain	clinicaltrials.gov
September 17, 2026	NCT07826871	Targeting HealthY Eating to Maintain Energy While Living With Cancer	University of Maryland, Baltimore	Phase 2	Recruiting	Fatigue in Cancer Survivors	132	United States	clinicaltrials.gov
September 17, 2026	NCT07825090	Association of ICU Admission Time, Age Stratification, and Clinical Frailty Scale With 30-Day Mortality in Geriatric Oncology Patients	Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital	Observational	Active not recruiting	Cancer, Frailty, Mortality	150	Turkey (Türkiye)	clinicaltrials.gov
September 17, 2026	NCT07824700	A Frailty-specific Prehabilitation Program for Mild to Moderately Frail Patients Undergoing Cardiac Surgeries/Procedures	The University of Hong Kong	Not applicable	Recruiting	Frailty, Thoracic Surgery	144	Hong Kong	clinicaltrials.gov
September 17, 2026	NCT07824141	Fall Prevention Pathways	Emory University	Not applicable	Recruiting	Old Age; Debility	50	United States	clinicaltrials.gov
September 11, 2026	NCT07815392	Preoperative Frailty and Postoperative Outcomes in Older Patients Undergoing Surgery for Gastrointestinal Cancer	Van Training and Research Hospital	Observational	Recruiting	Gastrointestinal Cancer, Frailty	100	Turkey (Türkiye)	clinicaltrials.gov
September 11, 2026	NCT07815158	Multi-Component Nutrition, Intrinsic Capacity, and Physical Function in Older Adults	National Yang Ming Chiao Tung University	Not applicable	Not yet recruiting	Sarcopenia, Intrinsic Capacity	70	Taiwan	clinicaltrials.gov
September 10, 2026	NCT07813702	URINARY INCONTINENCE AND GERIATRIC SYNDROMES	MERT UYSAL	Observational	Recruiting	Urinary Incontinence (UI), Urinary Incontinence, Urinary Incontinence in Old Age, Urinary Incontinence in Geriatric...	120	Turkey (Türkiye)	clinicaltrials.gov
September 9, 2026	NCT07808619	Longevity Metrics AI/ML Development Study	Longevity Metrics, Inc.	Observational	Recruiting	Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome, Cognitive Dysfunction, Frailty...	1,000,000	United States	clinicaltrials.gov
September 4, 2026	NCT07803900	Effect of Synchronized Transcutaneous Electrical Diaphragm Stimulation Using Surged Faradic Current Combined With Inspiratory Muscle...	Maharashtra University of Health Sciences	Not applicable	Completed	Chronic Kidney Disease, Frailty	42	India	clinicaltrials.gov
August 31, 2026	NCT07794657	Brief Training Program for General Practitioners on Malnutrition and Adapted Physical Activity	Nantes University Hospital	Not applicable	Completed	Malnutrition Elderly, Primary Care, General Practitioner Education, Older Adults (65 Years and Older), Frailty, Adapted...	40	France	clinicaltrials.gov
August 28, 2026	NCT07793708	Older Adults' Recovery Dynamics After Cardiac Surgery	University of Chile	Observational	Not yet recruiting	Frailty, Resilience, Cardiac Surgery Recovery	75	Chile	clinicaltrials.gov
August 26, 2026	NCT07787663	Promoting Autonomy Through ExerCisE (PACE) in Outpatient Geriatric Clinics	Université du Québec a Montréal	Not applicable	Completed	Frailty, Sarcopenia	162	Canada	clinicaltrials.gov
August 24, 2026	NCT07783204	ERAS Compliance and Hospital Stay After Open Heart Surgery	Bursa City Hospital	Observational	Completed	Cardiac Surgery, Nutritional Risk, Frailty	120	Turkey (Türkiye)	clinicaltrials.gov
August 20, 2026	NCT07776184	Multi-Component Delirium Prevention Bundle in Older Cardiac Intensive Care Unit Patients	Tel Aviv Medical Center	Not applicable	Active not recruiting	Delirium in Old Age, Delirium in the Intensive Care Unit, Delirium Confusional State, Delirium, Cardiac Intensive Care...	200	Israel	clinicaltrials.gov
August 19, 2026	NCT07772336	MItochondrial Intervention for Resilience in Older Adults With Coenzyme Q10	University Medical Centre Ljubljana	Not applicable	Not yet recruiting	Frailty, Aging, Mitochondria Health, Skin Aging, Mitochondrial Dysfunction	100		clinicaltrials.gov
August 3, 2026	NCT07742475	Funcional Recovery After Minithoracotomy or Sternotomy for CABG in Frail Patients	University of Sao Paulo General Hospital	Not applicable	Not yet recruiting	Frailty, Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)	194		clinicaltrials.gov
August 3, 2026	NCT07741292	Niaoduqing Granules in Older Adults With Impaired Kidney Function	Huashan Hospital	Phase 4	Recruiting	Chronic Kidney Disease	300	China	clinicaltrials.gov
July 31, 2026	NCT07740031	Development of a Frailty Risk Prediction Model and Preliminary Evaluation of a Risk-stratified Social Robot-assisted Intervention in...	The Hong Kong Polytechnic University	Not applicable	Not yet recruiting	Frailty	60		clinicaltrials.gov
July 31, 2026	NCT07738393	In-Person, Online, and Hybrid Healthy-Aging Education for Pre-Frailty and Frailty in Older Adults	University of Cadiz	Not applicable	Not yet recruiting	Frailty, Pre-Frailty	276	Spain	clinicaltrials.gov
July 29, 2026	NCT07732530	Acupoint Stimulation and Exercise for Taiwanese Pre-frail Older Adults	Tainan Hospital, Ministry of Health and Welfare	Not applicable	Recruiting	Frailty, Sleep Quality, Aging	30	Taiwan	clinicaltrials.gov
July 29, 2026	NCT07732478	Effects of a Community-based Multicomponent Physical Exercise Program on Physical Function, Frailty, and Sarcopenia in Older Adults From...	Universidad de Granada	Not applicable	Recruiting	Frailty/Sarcopenia, Frailty in Older Adults, Sarcopenia	300	Spain	clinicaltrials.gov
July 28, 2026	NCT07731529	Vivifrail Exercise Program in Nonagenarians: Effects on Function, Muscle, and Cognition	Federal University of Rio Grande do Sul	Not applicable	Enrolling by invitation	Frailty, Aging, Cognitive Decline	54	Brazil	clinicaltrials.gov
July 27, 2026	NCT07727876	Ready for Safe Cancer Treatment (RESET): A Comprehensive Perioperative Program for Surgical Oncology	Regional Specialist Hospital in Wroclaw	Not applicable	Recruiting	Neoplasms, Frailty, Surgical Procedures, Operative	12,800	Poland	clinicaltrials.gov
July 27, 2026	NCT07727811	Frailty Syndrome and Its Associated Factors Among Elderly Patients	Assiut University	Observational	Not yet recruiting	Geriatric Assessment	175		clinicaltrials.gov
July 24, 2026	NCT07726498	STRIDE: Strength of The Calf Muscles and Their Role In Declining Effectiveness of Movement With Aging	University of Leicester	Observational	Not yet recruiting	Sarcopenia, Aging, Muscle Weakness or Atrophy, Frailty	200	United Kingdom	clinicaltrials.gov
July 23, 2026	NCT07723339	BIOANCIENT_EX: Effects of a Physical Exercise Program in Centenarians of the BIOANCIENT Cohort: A Randomized Clinical Trial.	Fundacion Miguel Servet	Not applicable	Enrolling by invitation	Aging, Cellular Senescence, Biomarkers / Blood, Exercise, Frailty	60	Spain	clinicaltrials.gov
July 17, 2026	NCT07712276	The Effect of Teleconsultation, on the Reversibility of Frailty in Geriatric Patients Post Hospitalization	Universitas Indonesia	Not applicable	Not yet recruiting	Prefrail Elderly, Frail Elderly	116	Indonesia	clinicaltrials.gov
July 17, 2026	NCT07710456	Nutritional Status in Hospitalized Patients Over 65 Years of Age With Mental Disorders	University Psychiatric Clinic Ljubljana	Observational	Not yet recruiting	Malnutrition, Sarcopenia, Obesity, Sarcopenic Obesity, Frailty, Dysphagia, Mental Disorder	450		clinicaltrials.gov
July 17, 2026	NCT07709975	Analgesia Methods and Early Mobilization in Geriatric ICU Patients After Major Surgery	Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization	Observational	Recruiting	Postoperative Pain, Delirium - Postoperative, Frailty, Postoperative Care in Geriatric Intensive Care Patients	90	Turkey (Türkiye)	clinicaltrials.gov
July 16, 2026	NCT07707297	BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)	Fundacion Miguel Servet	Observational	Recruiting	Aging, Cellular Senescence, Biomarkers / Blood, Age-Related Diseases, Frailty	333	Spain	clinicaltrials.gov
July 15, 2026	NCT07705802	Outcome of Patients With Severe Mental Illness in the Intensive Care Unit	Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer	Observational	Not yet recruiting	Severe Mental Illness, Severe Mental Disorder	2,000	France	clinicaltrials.gov
July 15, 2026	NCT07705464	Safety Study of Intravenous MiraMSC in Older Adults With Mild to Moderate Frailty Syndrome	Miracle Biomedical Co., Ltd.	Phase 1	Not yet recruiting	Frailty	12		clinicaltrials.gov
July 14, 2026	NCT07701538	Frailty and Ultrasound-Guided Central Venous Catheterization Difficulty in Adult Cardiac Surgery Patients	Ankara City Hospital Bilkent	Observational	Recruiting	Frailty, Cardiac Surgery, Central Venous Catheter	280	Turkey (Türkiye)	clinicaltrials.gov
July 14, 2026	NCT07701382	Remote vs In-Person Prehabilitation for Kidney Transplant Candidates	Hospital Clinic of Barcelona	Not applicable	Not yet recruiting	Chronic Kidney Disease (CKD), Kidney Transplant, Frailty, Prehabilitation	84	Spain	clinicaltrials.gov
July 13, 2026	NCT07698912	The Effects of an AIoT-Based Exercise System on Frail Older Adults	National Cheng Kung University	Not applicable	Completed	Frail Older Adults	376	Taiwan	clinicaltrials.gov
July 10, 2026	NCT07696078	Frailty is a Risk Factor Postcholecystectomy	Zagazig University	Not applicable	Completed	Frailty, Gallbladder Diseases	Not listed		clinicaltrials.gov
July 7, 2026	NCT07687108	Improving Shared DECISion-making in oldEr Hip Fracture Patients Living With Frailty	University of Southampton	Observational	Not yet recruiting	Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Hip Fractures (ICD-10 72.01-72.2), Hip Fracture...	42	United Kingdom	clinicaltrials.gov
July 7, 2026	NCT07686146	Multicomponent Exercise and Frailty in Nursing Home Residents	Escoles Universitaries Gimbernat	Not applicable	Completed	Balance Impairment, Sarcopenia in Elderly, Frailty at Older Adults, Functional Decline, Fall Risk	66	Spain	clinicaltrials.gov
June 30, 2026	NCT07677319	SAGE-Heart : Senior Assessment fraGility and Post-opErative QALYs 1 Year After Emergency HEART Surgery for Patients Aged 75 and Older	University Hospital, Bordeaux	Not applicable	Recruiting	Frailty, Cardiac Surgery, QALYs	265	France	clinicaltrials.gov
June 30, 2026	NCT07677085	Effects of a Nurse-Led Comprehensive Intervention on Frailty and Self-Management Behaviors in Patients Undergoing Peritoneal Dialysis	Henan University	Not applicable	Completed	Peritoneal Dialysis (PD), Frailty Syndrome	72	China	clinicaltrials.gov
June 30, 2026	NCT07677072	Can Serum Lumican Level Identify a Hidden Fragility Phenotype Beyond Bone Mineral Density in Postmenopausal Women?	Kanuni Sultan Suleyman Training and Research Hospital	Observational	Recruiting	Osteoporosis, Postmenopausal Osteoporosis, Frailty, Fragility Fractures	98	Turkey (Türkiye)	clinicaltrials.gov
June 25, 2026	NCT07669168	Health Ahead Comparative Effectiveness Study	William Brandenburg, MD	Not applicable	Recruiting	Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services, Patient...	1,000,000	United States	clinicaltrials.gov
June 25, 2026	NCT07667764	P-POSSUM for Outcomes After Abdominal Surgery	Bach Mai Hospital	Observational	Active not recruiting	Abdominal Surgery, Postoperative Complications, Surgical Risk Prediction, Postoperative Mortality, Frailty	3,000	Vietnam	clinicaltrials.gov
June 23, 2026	NCT07663955	The SHAPE Project (Hospital System for Physical Activity and Active Participation) After Hospitalized Decompensation of Respiratory Chronic...	Hospital Universitari de Bellvitge	Not applicable	Not yet recruiting	Frailty, Sarcopenia, Hospital Discharge, Physical Activity, Acute Exacerbation Chronic Pulmonary Disease	90	Spain	clinicaltrials.gov
June 22, 2026	NCT07660653	Resistance-Based Multicomponent Training Plus Nutrition Supplementation for Intrinsic Capacity and Disability Risk in Chinese Rural Older...	Capital University of Physical Education and Sports, China	Not applicable	Completed	Frailty, Sarcopenia, Mobility Limitation, Nutritional Risk	220	China	clinicaltrials.gov
June 16, 2026	NCT07649525	Personalising Treatment for Myeloma Patients Based on Initial Response to NHS Treatment and Their Overall Fitness Level	University of Leeds	Phase 3	Recruiting	Multiple Myeloma (MM), Plasma Cell Leukemia (PCL)	1,226	United Kingdom	clinicaltrials.gov
June 15, 2026	NCT07646782	Human Observatory Study	Longevity Metrics, Inc.	Observational	Recruiting	Aging, Mortality, All-cause Mortality, Life Expectancy, Cardiovascular Diseases, Neoplasms, Cognitive Dysfunction...	1,000,000	United States	clinicaltrials.gov
June 12, 2026	NCT07646405	Combined Effects of NMES and LIRT on Muscle Strength, Girth, and Physical Endurance in the Geriatric Population	Riphah International University	Not applicable	Recruiting	Old Age; Debility	44	Pakistan	clinicaltrials.gov
June 11, 2026	NCT07643064	Multicomponent Exercise and Comprehensive Geriatric Assessment Program (FRAIL+AP) for Frail Older Adults in Primary Care	Alberto Bermejo Franco	Not applicable	Recruiting	Frail Elderly	200	Spain	clinicaltrials.gov
June 11, 2026	NCT07642765	EASIX Score and Post-Induction Hypotension in Frail Patients Undergoing Non-Cardiac Surgery	Konya City Hospital	Observational	Recruiting	Hypotension on Induction, Frailty, Anesthesia, General	160	Turkey (Türkiye)	clinicaltrials.gov
June 11, 2026	NCT07642726	Change in Cognition and Frailty After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus (iNPH)	Oslo University Hospital	Observational	Completed	Idiopathic Normal Pressure Hydrocephalus (INPH)	276	Norway	clinicaltrials.gov
June 10, 2026	NCT07638449	Silkworm Pupa Powder Improves Alzheimer's Disease	Zhejiang Provincial Tongde Hospital	Not applicable	Not yet recruiting	Alzheimer Disease, Sarcopenia, Asthenia, Frailty	100	China	clinicaltrials.gov
June 10, 2026	NCT07637890	Designing a Multicomponent Intervention for Improving Frailty. A Pilot Study in the Basque Country	Biogipuzkoa Health Research Institute	Not applicable	Completed	Frailty	32	Spain	clinicaltrials.gov
June 9, 2026	NCT07637383	IMPACT OF A MULTICOMPONENT PHYSICAL EXERCISE PROGRAM ON THE FUNCTIONAL CAPACITY OF PATIENTS ADMITTED TO AN INTERMEDIATE CARE HOSPITAL....	Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina	Not applicable	Recruiting	Functionality, Fragility	120	Spain	clinicaltrials.gov
June 8, 2026	NCT07634406	Nurse-Led Telehealth Frailty Management in Older Adults	Kutahya Health Sciences University	Not applicable	Completed	Frailty	122	Turkey (Türkiye)	clinicaltrials.gov
June 8, 2026	NCT07633964	An Study Looking at Percutaneous Coronary Intervention Outcomes for Octogenarians	Gloucestershire Hospitals NHS Foundation Trust	Observational	Not yet recruiting	Cardio Vascular Disease	850	United Kingdom	clinicaltrials.gov
June 3, 2026	NCT07624370	Frailty in the Elderly Oncological and Oncohematological Patient.	Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano	Observational	Enrolling by invitation	Sarcopenia in Elderly, Frailty/Sarcopenia, Oncological Patients, Hematologic Disease	160	Italy	clinicaltrials.gov
June 3, 2026	NCT07623694	Clinical and Functional Effectiveness Assessment of Personalized Management Programs for Patients With Frailty	Pirogov Russian National Research Medical University	Not applicable	Active not recruiting	Frailty, Frailty/Sarcopenia	115	Russia	clinicaltrials.gov
June 3, 2026	NCT07623122	Characterisation of Functional and Cognitive Responses Following Olfactory Stimulation and/or Functional Training in Older Adults.	Fundacion Miguel Servet	Not applicable	Completed	Healthy Aging, Frailty, Cognitive Decline, Olfactory Dysfunction, Physical Performance Decline in Older Adults	120	Spain	clinicaltrials.gov
June 2, 2026	NCT07621276	Frailty and Severity as Determinants of Hospital Cost in the ICU	Hospital H+ Queretaro	Observational	Completed	Frailty, Critical Illness, Hospital Costs	142	Mexico	clinicaltrials.gov
June 1, 2026	NCT07616219	Exergaming-based Sitting Tai Chi for Sarcopenia and/or Frailty	Hong Kong Metropolitan University	Not applicable	Enrolling by invitation	Sarcopenia in Elderly, Frailty at Older Adults	152	Hong Kong	clinicaltrials.gov
May 26, 2026	NCT07607236	Muscle Ultrasound for Sarcopenia Assessment in Kidney Transplant Recipients	Sichuan Provincial People's Hospital	Observational	Not yet recruiting	Sarcopenia, Kidney Transplantation, Muscle Wasting	140	China	clinicaltrials.gov
May 26, 2026	NCT07607041	Evolution of Physical Frailty and Patient-Reported Outcome Measures in Kidney Transplant Candidates: A Mixed-Methods Longitudinal Study...	Hospital del Mar	Observational	Not yet recruiting	Kidney Failure, Chronic, Frailty, Quality of Life, Kidney Transplantation, Patient Reported Outcome Measures	150		clinicaltrials.gov
May 26, 2026	NCT07605936	Frailty in Older Adults With Prostate Cancer: a Prospective Cohort Study	University of Limerick	Observational	Recruiting	Frailty at Older Adults, Prostate Cancer	80	Ireland	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Ankara City Hospital Bilkent	6	November 4, 2026
Fundacion Miguel Servet	6	September 21, 2026
Assiut University	5	September 23, 2026
National Taiwan University Hospital	5	March 19, 2025
The University of Hong Kong	4	September 17, 2026
Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina	4	June 9, 2026
Cardenal Herrera University	3	November 6, 2026
Universidad de Burgos	3	October 28, 2026
The Hong Kong Polytechnic University	3	October 6, 2026
Fundación para la Investigación del Hospital Clínico de Valencia	3	September 18, 2026
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital	3	September 17, 2026
Longevity Metrics, Inc.	3	September 9, 2026
University of Limerick	3	May 26, 2026
Universidad Francisco de Vitoria	3	April 29, 2026
National University of Singapore	3	April 9, 2026
University of Iceland	3	March 11, 2026
Chinese PLA General Hospital	3	January 7, 2026
Istituti Clinici Scientifici Maugeri SpA	2	November 6, 2026
Konya City Hospital	2	November 4, 2026
Samara State Medical University	2	October 27, 2026

By phase

Phase	New trials	Latest
Not applicable	188	November 6, 2026
Observational	143	November 6, 2026
Phase 2	5	September 17, 2026
Phase 1	4	October 2, 2026
Phase 4	2	August 3, 2026
Phase 3	1	June 16, 2026
Phase 1/2	1	March 2, 2026
Early phase 1	1	March 11, 2025

By country

Country	New trials	Latest
Spain	53	November 6, 2026
Turkey (Türkiye)	43	November 4, 2026
China	21	September 29, 2026
United States	19	September 17, 2026
Taiwan	18	October 19, 2026
France	14	October 26, 2026
Italy	13	November 6, 2026
United Kingdom	10	November 4, 2026
Hong Kong	8	September 17, 2026
Canada	8	August 26, 2026
Singapore	6	April 13, 2026
Sweden	5	October 1, 2026
Switzerland	5	September 23, 2026
Denmark	5	April 6, 2026
Chile	4	September 18, 2026
Indonesia	4	July 17, 2026
Ireland	4	May 26, 2026
Belgium	4	March 25, 2026
Portugal	4	March 23, 2026
Germany	4	March 11, 2026
South Korea	4	September 23, 2025
Russia	3	October 27, 2026
Vietnam	3	June 25, 2026
Mexico	3	June 2, 2026
Iceland	3	March 11, 2026

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.