Data / New clinical trials / Fibrosis
New Fibrosis clinical trials: 172 posted since Nov 2024
The full list. New Fibrosis clinical trials: 172 rows for $8.60, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 8 rows a month. The new rows come each week by email, $19 a month.
Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (sponsor class, condition groups (MeSH), interventions, start date, enrollment type, location countries and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.
For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/fibrosis, and every list with its row count and price is at https://specstream.ai/data/lists.json.
Updated November 5, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).
172 clinical studies in fibrosis were first posted on ClinicalTrials.gov from November 12, 2024 to November 5, 2026; 19 have an industry sponsor and 127 are recruiting or about to. The newest, NCT07918378, was posted on November 5, 2026: Treatment Outcomes and Predictors After Endovascular Intervention for Portal Hypertension-Related... (University Medical Center Ho Chi Minh City (UMC)).
The request: Every new Fibrosis clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.
SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.
- 172New trials
- 19Industry sponsored
- 127Recruiting or not yet
- November 5, 2026Latest posted
Newest trials
The newest 100 of 172, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.
| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
|---|---|---|---|---|---|---|---|---|---|
| November 5, 2026 | NCT07918378 | Treatment Outcomes and Predictors After Endovascular Intervention for Portal Hypertension-Related Gastrointestinal Bleeding in Cirrhosis | University Medical Center Ho Chi Minh City (UMC) | Observational | Recruiting | Cirrhosis, Portal Hypertension Related to Cirrhosis, GI Bleeding, Gastrointestinal Bleeding | 167 | Vietnam | clinicaltrials.gov |
| October 22, 2026 | NCT07889726 | "Anticipant"-TIPS After a First Portal-hypertension-related Complication in Cirrhosis | University Hospital, Toulouse | Not applicable | Not yet recruiting | Cirrhosis | 266 | France | clinicaltrials.gov |
| October 15, 2026 | NCT07876648 | Prospective Trial of [18F]AlF-FAPI-74 for PET Imaging of Fibroblast Activation Protein in Patients With Endometriosis | Universitaire Ziekenhuizen KU Leuven | Not applicable | Recruiting | Endometriosis, Deep Infiltrating Endometriosis, Women, Superficial Peritoneal Endometriosis, Fibrosis | 64 | Belgium | clinicaltrials.gov |
| October 13, 2026 | NCT07870850 | Clinical Outcomes in Patients Presenting With Acute Variceal Bleeding | Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor | Observational | Completed | Portal Hypertension Related to Cirrhosis, Variceal Bleeding, Cirrhoses, Liver | 149 | Romania | clinicaltrials.gov |
| October 9, 2026 | NCT07867574 | AGED Diagnostics Clinical Validation Study | Active Genomes Expressed Diagnostics, Corp | Observational | Not yet recruiting | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASLD (Metabolic Dysfunction-Associated Steatotic Liver... | 500 | United States | clinicaltrials.gov |
| October 6, 2026 | NCT07860814 | Ultrasound Biomarkers for Assessing Eligibility and Response to Resmetirom Therapy | Radnet Management, Inc. | Observational | Not yet recruiting | Metabolic Dysfunction-steatohepatitis (MASH) | 524 | United States | clinicaltrials.gov |
| October 2, 2026 | NCT07855913 | EUS-Guided Coil and Glue vs Glue Injection for Bleeding Gastric Varices in Cirrhosis | Medanta, The Medicity, India | Not applicable | Recruiting | Gastric Varices Bleeding, Cirrhosis | 110 | India, United States | clinicaltrials.gov |
| October 1, 2026 | NCT07851324 | Stromal Desmoplastic Reaction as a Predictive Factor for Lymph Node Metastasis in Medullary Thyroid Cancer | Aristotle University Of Thessaloniki | Observational | Not yet recruiting | Medullary Thyroid Carcinoma | 74 | clinicaltrials.gov | |
| September 15, 2026 | NCT07820995 | Mechanistic Evaluation of Atrasentan in Patients With IgA Nephropathy (IgAN) | University of Illinois Chicago | Phase 4 | Not yet recruiting | IgA Nephropathy (IgAN), Immunoglobulin A Nephropathy (IgAN) | 20 | United States | clinicaltrials.gov |
| September 15, 2026 | NCT07820917 | Chronic Pain Optimization and Management for Relief and Functionality With TEA in Cirrhosis | University of Michigan | Not applicable | Not yet recruiting | Cirrhosis | 100 | United States | clinicaltrials.gov |
| September 11, 2026 | NCT07816185 | A Phase 3 Trial of Inhaled Mosliciguat in PH-ILD (PHrontier) | Pulmovant, Inc. | Phase 3 | Recruiting | Pulmonary Hypertension, Interstitial Lung Disease, Vascular Diseases, Cardiovascular Diseases, Fibrosis | 376 | United States | clinicaltrials.gov |
| September 10, 2026 | NCT07811713 | Effect of LSD on Renal Function in Cirrhotic Patients With Portal Hypertension | Northern Jiangsu People's Hospital | Observational | Completed | Cirrhosis, Liver, Splenectomy; Status, Renal Function Abnormal, Portal Hypertension | 496 | clinicaltrials.gov | |
| September 10, 2026 | NCT07811700 | Effect of LSD on Lipid Profiles Within 1 Year Postoperatively in Cirrhosis Patients With Portal Hypertension Bleeding | Northern Jiangsu People's Hospital | Observational | Completed | Lipid Profiles, Cirrhosis, Liver, Portal Hypertension, Splenectomy; Status | 150 | China | clinicaltrials.gov |
| September 9, 2026 | NCT07810855 | Using Bedside Ultrasound to Understand Fluid Management in Patients With Chronic Liver Disease | Royal Free Hospital NHS Foundation Trust | Observational | Not yet recruiting | Cirrhosis, Ascites Hepatic, Fluid Balance | 100 | clinicaltrials.gov | |
| September 9, 2026 | NCT07808970 | Prospective Stage-Stratified Histopathologic Study and Proposed Disease-Evolution Model of Gluteal Permanent Synthetic Filler Complications | Research Inc | Observational | Not yet recruiting | Foreign-Body Reaction, Granulomatous Disease, Soft Tissue Necrosis Lower Limb, Gluteal Permanent Synthetic Filler... | 200 | Colombia | clinicaltrials.gov |
| September 2, 2026 | NCT07800598 | Role of Allopurinol in Prevention of Complications Related to Decompensated Cirrhosis of Liver | Bangladesh Medical University | Phase 4 | Recruiting | Cirrhoses, Liver, Decompensated Cirrhosis of Liver | 54 | Bangladesh | clinicaltrials.gov |
| September 1, 2026 | NCT07797114 | Predictors of Mortality in Cirrhotic Patients With Acute Kidney Injury | Assiut University | Observational | Not yet recruiting | AKI in Cirrhosis | 100 | clinicaltrials.gov | |
| September 1, 2026 | NCT07797101 | Body-weight Reduction Effect on Portal Hypertension in Compensated Cirrhosis | The Second Affiliated Hospital of Chongqing Medical University | Not applicable | Not yet recruiting | Cirrhosis, Portal Hypertension, Fatty Liver Disease, GLP-1 | 50 | clinicaltrials.gov | |
| August 31, 2026 | NCT07795476 | Artificial Intelligence For Outcomes Research in Crohn's Disease: Digital Pathology Assessment of Fibrosis and Association With Patient... | PharmaNest, Inc | Observational | Not yet recruiting | Crohn Disease, Fibrostenotic Crohn's Disease, CD - Crohn's Disease | 100 | Spain | clinicaltrials.gov |
| August 28, 2026 | NCT07792850 | The Application of Lifestyle Enhancing Validated Integrative Therapies for Everyday Pain in Cirrhosis | University of Pennsylvania | Not applicable | Not yet recruiting | Cirrhoses, Liver | 625 | United States | clinicaltrials.gov |
| August 20, 2026 | NCT07777705 | Application of Different Scores in Predicting Outcomes of Cirrhotic Patients Awaiting Liver Transplantation | Assiut University | Observational | Not yet recruiting | Liver Cirrhosis, Liver Transplant | 153 | clinicaltrials.gov | |
| August 20, 2026 | NCT07775638 | Detecting Liver Fibrosis in Patients At-risk | Helse Stavanger HF | Observational | Not yet recruiting | Fatty Liver, NAFLD - Non-Alcoholic Fatty Liver Disease, Nash, MASLD (Metabolic Dysfunction-Associated Steatotic Liver... | 1,200 | Norway | clinicaltrials.gov |
| August 13, 2026 | NCT07763015 | Study of Resmetirom in Children and Adolescents With MASH | Madrigal Pharmaceuticals, Inc. | Phase 2 | Recruiting | MASH, MASH - Metabolic Dysfunction-Associated Steatohepatitis | 61 | United States | clinicaltrials.gov |
| August 6, 2026 | NCT07750587 | Predicting Response and Exposure Changes in Cirrhosis for Effectiveness | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Not applicable | Not yet recruiting | Liver Cirrhosis | 45 | clinicaltrials.gov | |
| July 30, 2026 | NCT07737444 | Association of Lipoprotein(a) With Postoperative Atrial Fibrillation | Anthony Tang | Observational | Not yet recruiting | POAF, Atrial Fibrillation (AF) | 20 | clinicaltrials.gov | |
| July 20, 2026 | NCT07715500 | Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications | Institute of Liver and Biliary Sciences, India | Not applicable | Recruiting | Chronic Liver Disease and Cirrhosis, Liver Transplant; Complications, Donor Hepatectomy | 100 | India | clinicaltrials.gov |
| July 17, 2026 | NCT07712679 | Evaluation of Kidney Fibrosis Via FAPI PET/CT | Medical University of Vienna | Not applicable | Recruiting | Chronic Kidney Disease | 30 | Austria | clinicaltrials.gov |
| July 15, 2026 | NCT07704892 | A Study to Investigate Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to... | GlaxoSmithKline | Phase 3 | Recruiting | Metabolic Dysfunction-associated Steatohepatitis | 380 | Japan, United States | clinicaltrials.gov |
| July 14, 2026 | NCT07703540 | Inferior Vena Cava Pressure as Alternative to Hepatic Venous Pressure for EUS-guided Portal Pressure Gradient Measurement | University Hospital Muenster | Observational | Completed | Cirrhosis, Liver Disease Chronic, Portal Hypertension | 40 | Germany | clinicaltrials.gov |
| July 14, 2026 | NCT07701993 | A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With... | GlaxoSmithKline | Phase 3 | Recruiting | Metabolic Dysfunction-associated Steatohepatitis | 1,740 | Japan, United States | clinicaltrials.gov |
| July 6, 2026 | NCT07685353 | Influence of Donor and Recipient Genetic Polymorphisms on Graft Steatosis After Liver Transplant | Institute of Liver and Biliary Sciences, India | Observational | Recruiting | Chronic Liver Disease and Cirrhosis | 50 | India | clinicaltrials.gov |
| July 1, 2026 | NCT07679893 | Phase 2 Clinical Trial of MNKD-201 (Nintedanib Dry Powder Inhalation) in Patients With Idiopathic Pulmonary Fibrosis | Mannkind Corporation | Phase 2 | Recruiting | Idiopathic Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis (IPF) | 153 | Canada | clinicaltrials.gov |
| June 25, 2026 | NCT07668778 | Evaluation of a Modified Bowel Preparation Regimen in Cirrhotic Patients Undergoing Colonoscopy | Hospital do Divino Espírito Santo de Ponta Delgada | Phase 3 | Not yet recruiting | Cirrhosis, Bowel Preparation | 252 | Portugal | clinicaltrials.gov |
| June 25, 2026 | NCT07667608 | Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting... | Assiut University | Observational | Not yet recruiting | Cirrhosis of the Liver, Ascites, Pleural Effusion Disorder, Hepatocellular Carcinoma (HCC), Sarcopenia, Diaphragm... | 120 | clinicaltrials.gov | |
| June 18, 2026 | NCT07658222 | Prospective Investigation of Cirrhotic Cardiomyopathy in Humans | Vanderbilt University Medical Center | Observational | Recruiting | Cirrhotic Cardiomyopathy | 440 | United States | clinicaltrials.gov |
| June 16, 2026 | NCT07652203 | Impact of Propranolol on the Prognosis of Patients With Decompensated Cirrhosis and MELD Score > 9 | General Hospital of Shenyang Military Region | Not applicable | Not yet recruiting | Cirrhosis | 466 | China | clinicaltrials.gov |
| June 16, 2026 | NCT07652151 | UNMASK: Unveiling the Pathobiology of Metabolic Dysfunction-Associated Steatotic Liver Disease for the Discovery of Novel Therapeutics and... | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | Not applicable | Recruiting | MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease) | 450 | Italy, Spain, Turkey (Türkiye) | clinicaltrials.gov |
| June 16, 2026 | NCT07651683 | Clinical Characteristics of Recompensation | Third Affiliated Hospital, Sun Yat-Sen University | Observational | Active not recruiting | Cirrhosis, Alcohol Related Liver Disease, HBV (Hepatitis B Virus), Recompensation | 300 | China | clinicaltrials.gov |
| June 15, 2026 | NCT07647978 | Development of a Predictive Score for the Risk of Infection in the Immediate Post-liver-transplant Period | Hospices Civils de Lyon | Observational | Not yet recruiting | Cirrhosis, Acute Hepatitis, Liver, mHLA-DR | 279 | France | clinicaltrials.gov |
| June 11, 2026 | NCT07642297 | TL1A Inhibition in Systemic Sclerosis-Related Skin Fibrosis and Immunological Alterations: A Proof-of-Concept In Vitro Study (FIBROSTOP) | Fondazione Policlinico Universitario Campus Bio-Medico | Observational | Not yet recruiting | Systemic Sclerosis (SSc), Diffuse Cutaneous Systemic Sclerosis, Skin Fibrosis | 20 | Italy | clinicaltrials.gov |
| June 8, 2026 | NCT07634237 | Personalized Nutritional Intervention in Patients Undergoing TIPS Insertion for Refractory Ascites to Prevent Overt Hepatic Encephalopathy | McGill University Health Centre/Research Institute of the McGill University Health Centre | Not applicable | Not yet recruiting | Cirrhosis, Refractory Ascites, TIPS Insertion | 50 | Canada | clinicaltrials.gov |
| June 8, 2026 | NCT07631637 | Study to Evaluate ALN-CIDEB in Adults With Fibrotic Metabolic Dysfunction-Associated Steatohepatitis (MASH) | Regeneron Pharmaceuticals | Phase 2 | Recruiting | Metabolic Dysfunction-Associated Steatohepatitis, MASH | 360 | Puerto Rico, United Kingdom, United States | clinicaltrials.gov |
| June 1, 2026 | NCT07616466 | Prophylactic Antibiotics in the Endoscopic Secondary Prevention of Cirrhotic Patients With Varices: a Retrospective Study | Second Affiliated Hospital, Zhejiang University, School of Medicine | Observational | Completed | Cirrhosis, Liver Hypertension, Portal Variceal Hemorrhage | 480 | China | clinicaltrials.gov |
| May 22, 2026 | NCT07604272 | Reversing InGuinal Hernia Trial: The Evaluation of Sex Hormones to Reverse Inguinal Hernias in Males | Northwestern University | Phase 1 | Recruiting | Inguinal Hernia Unilateral, Inguinal Hernia Bilateral, Inguinal Hernia Without Obstruction or Gangrene, Inguinal... | 30 | United States | clinicaltrials.gov |
| May 14, 2026 | NCT07588373 | Effect of Laparoscopic Splenectomy on Lipid Profiles in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up) | Northern Jiangsu People's Hospital | Observational | Not yet recruiting | Cirrhosis, Splenectomy; Status, Hypersplenism, Lipid Profiles | 30 | China | clinicaltrials.gov |
| May 14, 2026 | NCT07588334 | Effect of LSD on Lipid Profiles in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up) | Northern Jiangsu People's Hospital | Observational | Not yet recruiting | Cirrhosis, Liver, Splenectomy; Status, Portal Hypertension, Lipid Profiles | 30 | China | clinicaltrials.gov |
| May 14, 2026 | NCT07587671 | Underdilated VCX-TIPS Versus EVL Plus NSBB for Secondary Prophylaxis of Variceal Bleeding in Cirrhosis | West China Hospital | Not applicable | Not yet recruiting | Liver Cirrhosis, Portal Hypertension, Gastroesophageal Varices Bleeding, Esophageal Varices, Hepatic Encephalopathy | 240 | China | clinicaltrials.gov |
| May 14, 2026 | NCT07585786 | Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up) | Northern Jiangsu People's Hospital | Observational | Not yet recruiting | Cirrhosis, Liver, Splenectomy; Status, Renal Function Abnormal, Portal Hypertension | 30 | clinicaltrials.gov | |
| May 14, 2026 | NCT07585773 | Effect of Laparoscopic Splenectomy on Renal Function in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up) | Northern Jiangsu People's Hospital | Observational | Not yet recruiting | Cirrhosis, Splenectomy; Status, Hypersplenism, Kidney Function Issue | 30 | China | clinicaltrials.gov |
| May 5, 2026 | NCT07568275 | Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance | The Cleveland Clinic | Early phase 1 | Active not recruiting | Septic Shock, Cirrhosis, Vasodilatory Shock, Acute Kidney Injury | 30 | United States | clinicaltrials.gov |
| May 4, 2026 | NCT07565337 | The Application of Biomarkers in the Care of Patients With Atrial Fibrillation | National Taiwan University Hospital | Observational | Withdrawn | Atrial Fibrillation, Biomarker | 0 | Taiwan | clinicaltrials.gov |
| April 28, 2026 | NCT07554183 | 4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in Cirrhosis | Assistance Publique - Hôpitaux de Paris | Not applicable | Recruiting | Cirrhosis, Portal Hypertension | 60 | France | clinicaltrials.gov |
| April 27, 2026 | NCT07552870 | Intravenous Ciprofloxacin Versus Intravenous Ceftriaxone: Spontaneous Bacterial Peritonitis in Cirrhosis of Liver | Shahida Islam Medical Complex | Not applicable | Completed | Cirrhosis | 310 | Pakistan | clinicaltrials.gov |
| April 16, 2026 | NCT07533565 | A Pilot Study of Mirabegron and Montelukast in Cirrhotic Patients | Kafrelsheikh University | Phase 4 | Completed | Cirrhosis, Asthma | 78 | Egypt | clinicaltrials.gov |
| April 14, 2026 | NCT07529262 | Can Aspirin Reduce the Risk of HCC in Cirrhosis: The AspiRe HCC Trial | Curtin University | Phase 3 | Not yet recruiting | Liver Cirrhosis | 890 | clinicaltrials.gov | |
| April 14, 2026 | NCT07528690 | Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE) | VA Office of Research and Development | Phase 2 | Not yet recruiting | Hepatic Encephalopathy, Cirrhosis | 162 | United States | clinicaltrials.gov |
| April 9, 2026 | NCT07521332 | Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis | Asian Institute Of Medical Sciences | Phase 4 | Recruiting | Cirrhosis, Esophageal and Gastric Varices, Ascites, Hepatic Encephalopathy, Portal Vein Thrombosis, Portal Hypertension | 220 | Pakistan | clinicaltrials.gov |
| April 2, 2026 | NCT07506642 | Patient Reported Outcomes In Liver Biopsy (EUS vs. Percutaneous) | University Hospital Muenster | Observational | Completed | Chronic Liver Disease (CLD), Liver Transplantation, Cirrhosis | 102 | Germany | clinicaltrials.gov |
| March 19, 2026 | NCT07481877 | Portosystemic Shunt-associated Pulmonary Hypertension Multi-center Prospective Cohort Study | Chinese Pulmonary Vascular Disease Research Group | Observational | Not yet recruiting | Portosystemic Shunt, Pulmonary Hypertension | 300 | clinicaltrials.gov | |
| March 19, 2026 | NCT07481734 | Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study) | Hudson Biotech | Phase 2 | Recruiting | Metabolic Associated Steatotic Liver Disease, Nonalcoholic Steatohepatitis, Hepatic Steatosis | 120 | China | clinicaltrials.gov |
| March 18, 2026 | NCT07480096 | Efficacy and Safety of Lemborexant for Patients With Cirrhosis and Sleep Problems | Universitas Indonesia | Phase 2 | Completed | Cirrhosis, Liver Cirrhosis, Sleep Quality, Insomnia, Hepatic Encephalopathy | 82 | Indonesia | clinicaltrials.gov |
| March 16, 2026 | NCT07473375 | Indicators Affecting PVT Recanalization | Shanghai Zhongshan Hospital | Observational | Recruiting | Portal Vein Thrombosis, Cirrhosis, Portal Hypertension Related to Cirrhosis, Portal Hypertension, Noncirrhotic | 1,500 | China | clinicaltrials.gov |
| March 13, 2026 | NCT07471542 | Copper Supplementation in Cirrhosis | University of Washington | Not applicable | Recruiting | Cirrhosis, Chronic Liver Disease, Fibrosis, Infection | 30 | United States | clinicaltrials.gov |
| March 13, 2026 | NCT07469319 | Biannual Screening for HCC Offered to Patients With Cirrhosis. Introducing Surveillance for Hepatocellular Carcinoma (HCC) in the Central... | University of Aarhus | Not applicable | Recruiting | Hepatocellular Carcinoma (HCC), Cirrhosis | 617 | Denmark | clinicaltrials.gov |
| March 11, 2026 | NCT07465003 | Cohort Study of Chronic Liver Disease Complicated by Sepsis | The Second Affiliated Hospital of Chongqing Medical University | Observational | Not yet recruiting | Cirrhosis, Sepsis | 1,600 | clinicaltrials.gov | |
| March 10, 2026 | NCT07462091 | Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection | Northern Jiangsu People's Hospital | Not applicable | Recruiting | Cirrhosis, Hypersplenism, Hypertension, Portal | 15 | China | clinicaltrials.gov |
| March 10, 2026 | NCT07461545 | Efficacy of Apixaban in the Treatment of Portal Vein Thrombosis Occurring More Than One Year After LS | Northern Jiangsu People's Hospital | Not applicable | Recruiting | Cirrhosis, Splenectomy, Portal Vein Thrombosis, Hypertension, Portal | 20 | China | clinicaltrials.gov |
| March 10, 2026 | NCT07461532 | Efficacy of Apixaban in Treating Portal Vein Thrombosis Occurring More Than One Year After LSD | Northern Jiangsu People's Hospital | Not applicable | Recruiting | Cirrhosis, Splenectomy, Portal Vein Thrombosis, Hypertension, Portal | 20 | China | clinicaltrials.gov |
| March 6, 2026 | NCT07455175 | Observational Clinical Study on the Association Between Lactate-mediated Gut Microbiota Alterations and Disease Progression in Liver... | Zhujiang Hospital | Observational | Not yet recruiting | Cirrhosis | 200 | China | clinicaltrials.gov |
| March 4, 2026 | NCT07450144 | A Large Language Model-based Chatbot for Alcohol Reduction in Patients With Steatotic Liver Disease | The University of Hong Kong | Not applicable | Recruiting | Steatotic Liver Disease | 50 | Hong Kong | clinicaltrials.gov |
| February 27, 2026 | NCT07438288 | Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis | Singapore General Hospital | Observational | Recruiting | Cirrhosis and Chronic Liver Disease | 2,200 | Singapore | clinicaltrials.gov |
| February 27, 2026 | NCT07437638 | Clinical Efficacy and Survival Prediction Analysis of Transjugular Intrahepatic Portosystemic Shunt in Patients With Liver Cirrhosis | The Second Affiliated Hospital of Chongqing Medical University | Observational | Active not recruiting | Liver Cirrhosis, Hepatic Encephalopathy, TIPS | 624 | China | clinicaltrials.gov |
| February 20, 2026 | NCT07424963 | Hepatic Venous Pressure Gradient Versus Endoscopic Ultrasound-Guided Portal Pressure Gradient - Comparative Analysis (HEPCA) | Military University Hospital, Prague | Not applicable | Recruiting | Cirrhosis, Portal Hypertension, EUS, Non-Cirrhotic Portal Hypertension, HVPG, Hepatic Venous Pressure Gradient | 40 | Czechia | clinicaltrials.gov |
| February 18, 2026 | NCT07417163 | LiverSleep: A Behavioral Sleep Intervention for Patients With Cirrhosis and Insomnia | Massachusetts General Hospital | Not applicable | Completed | Cirrhosis, Insomnia | 11 | United States | clinicaltrials.gov |
| February 17, 2026 | NCT07414095 | Multidimensional Frailty Assessment and Post-Transplant Outcomes in Liver Transplant Candidates | Izmir Bakircay University | Observational | Recruiting | End-Stage Liver Disease, Liver Transplantation, Cirrhosis | 60 | Turkey (Türkiye) | clinicaltrials.gov |
| February 12, 2026 | NCT07405944 | Vericiguat and Reverse Remodeling Indices in Heart Failure | University Medical Centre Ljubljana | Phase 4 | Recruiting | Heart Failure With Reduced Ejection Fraction (HFrEF), Chronic Heart Failure | 70 | Slovenia | clinicaltrials.gov |
| February 9, 2026 | NCT07395141 | Albumin in Acute Variceal Bleeding | King George's Medical University | Phase 3 | Not yet recruiting | Acute Variceal Bleeding, Cirrhosis | 60 | India | clinicaltrials.gov |
| February 6, 2026 | NCT07393074 | PSYLIVER-PILOTE: Involvement of the Autonomic Nervous System in Hepatocellular Carcinoma (HCC) | Hospices Civils de Lyon | Not applicable | Recruiting | Hepato Cellular Carcinoma, Cirrhosis, Autonomic Nervous System, Central Nervous System | 100 | France | clinicaltrials.gov |
| February 5, 2026 | NCT07390344 | VIATORR® TIPS Study Evaluating 6-10mm Diameters (VIATIPS) | W.L.Gore & Associates | Observational | Recruiting | Ascites, Variceal Bleeding, Portal Hypertension Related to Cirrhosis | 152 | Italy, United States | clinicaltrials.gov |
| January 28, 2026 | NCT07373769 | Ultrasound Liver Imaging for Classification of Metabolic Dysfunction-associated Steatotic Liver Disease | University of British Columbia | Observational | Not yet recruiting | Metabolic Dysfunction-Associated Steatotic Liver Disease | 145 | Canada | clinicaltrials.gov |
| January 26, 2026 | NCT07368309 | Clinical Management Strategies for Patients With Cirrhosis and Esophagogastric Varices Complicated by Early-stage Upper Gastrointestinal... | Renmin Hospital of Wuhan University | Observational | Completed | Cirrhosis, Esophagogastric Varices, Early-stage Upper Gastrointestinal Cancer | 206 | China | clinicaltrials.gov |
| January 26, 2026 | NCT07365709 | Liver Cirrhosis Complicated by Clinically Significant Portal Hypertension | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Not applicable | Not yet recruiting | Portal Hypertension, Spleen Disease, Cirrhosis | 107 | clinicaltrials.gov | |
| January 22, 2026 | NCT07359742 | Assessing Signatures for Fibrosis Detection in Chronic Liver Disease: A Step Beyond Conventional Biomarkers | Universitair Ziekenhuis Brussel | Not applicable | Recruiting | Chronic Liver Disease (CLD), Fibrosis of Liver | 110 | Belgium | clinicaltrials.gov |
| January 21, 2026 | NCT07354789 | The Feasibility, Safety, and Efficacy of EUS-Guided PSE: A Cohort Study | Qilu Hospital of Shandong University | Not applicable | Not yet recruiting | Cirrhosis, Portal Hypertension, Bleeding | 50 | clinicaltrials.gov | |
| January 20, 2026 | NCT07349654 | Underdilated-stent Technique Improves Post-TIPS Encephalopathy | The Second Affiliated Hospital of Chongqing Medical University | Not applicable | Recruiting | Liver Cirrhosis, Variceal Bleeding, Cirrhosis, Ascites Hepatic, Hepatic Encephalopathy (HE) | 72 | China | clinicaltrials.gov |
| January 15, 2026 | NCT07345052 | Western Sweden Systemic Sclerosis Project | Sahlgrenska University Hospital | Observational | Recruiting | Scleroderma, Systemic, Fibrosis; Skin, Fibrosis Lung, Interstitial Lung Disease Due to Systemic Disease | 150 | Sweden | clinicaltrials.gov |
| January 13, 2026 | NCT07335601 | Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH | Madrigal Pharmaceuticals, Inc. | Phase 2 | Recruiting | MASH - Metabolic Dysfunction-Associated Steatohepatitis | 120 | Canada, United States | clinicaltrials.gov |
| January 12, 2026 | NCT07333183 | A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD | Pulmovant, Inc. | Phase 2 | Recruiting | Pulmonary Hypertension, Interstitial Lung Disease (ILD), Lung Diseases, Vascular Diseases, Cardiovascular Diseases... | 20 | United States | clinicaltrials.gov |
| January 8, 2026 | NCT07325357 | Effect of Pirfenidone on TA Fibrosis | Shanghai Zhongshan Hospital | Phase 4 | Not yet recruiting | Takayasu Arteritis | 92 | clinicaltrials.gov | |
| January 7, 2026 | NCT07322237 | DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 4 | Recruiting | Cirrhotic Cardiomyopathy, Empagliflozin, Cardiometabolic Risk Factors, Cirrhosis | 400 | India | clinicaltrials.gov |
| January 6, 2026 | NCT07319299 | STOP HCC-GAAD-APAC-Thailand | Mahidol University | Not applicable | Enrolling by invitation | Hepatecellular Carcinoma, Cirrhosis, HBV Infection | 2,100 | Thailand | clinicaltrials.gov |
| December 31, 2025 | NCT07312136 | MASLD in Type 2 Diabetes in Primary Care - a Follow-up Study | Linkoeping University | Observational | Enrolling by invitation | MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis, Advanced Fibrosis, Sarcopenia, Obesity &... | 317 | Sweden | clinicaltrials.gov |
| December 15, 2025 | NCT07281846 | TIPS With or Without BCAA | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Not applicable | Recruiting | BCAA, Cirrhosis, Portal Hypertension Related to Cirrhosis, Sarcopenia, Transjugular Intrahepatic Portosystemic Shunt | 164 | China | clinicaltrials.gov |
| December 12, 2025 | NCT07280390 | Microplastics, Cirrhosis and Portal Hypertension | Post Graduate Institute of Medical Education and Research, Chandigarh | Observational | Recruiting | Cirrhosis, Microplastics, Portal Hypertension Related to Cirrhosis, Nanoplastics, Pollution, Cirrhosis and Chronic... | 30 | India | clinicaltrials.gov |
| December 11, 2025 | NCT07277998 | Alternating Triamcinolone and Platelet-Rich Plasma Therapy for Oral Submucous Fibrosis | Karachi Medical and Dental College | Not applicable | Not yet recruiting | Oral Submucous Fibrosis | 40 | Pakistan | clinicaltrials.gov |
| December 8, 2025 | NCT07270601 | Development of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis | ContextVision AB | Not applicable | Recruiting | MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, NAFLD - Non-Alcoholic Fatty Liver Disease | 110 | United States | clinicaltrials.gov |
| December 5, 2025 | NCT07268196 | Impact of Liver Transplantation on Sexual Life and Function | Institute of Liver and Biliary Sciences, India | Observational | Recruiting | Chronic Liver Disease and Cirrhosis | 100 | India | clinicaltrials.gov |
| December 5, 2025 | NCT07267260 | Evaluating the Efficacy of Vonoprazan in Preventing Post-Endoscopic Variceal Band Ligation Ulcers: A Randomized Controlled Trial | King Edward Medical University | Phase 2 | Recruiting | Cirrhoses, Liver | 154 | Pakistan | clinicaltrials.gov |
| November 25, 2025 | NCT07249112 | DEFINITION OF THE GENOMIC LANDSCAPE OF MASLD | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Not applicable | Completed | Cirrhosis, MASLD | 2,880 | Italy | clinicaltrials.gov |
| November 17, 2025 | NCT07230964 | Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacement Fibrosis | Dermed Diagnostics, Inc. | Not applicable | Recruiting | Aortic Stenosis | 6 | United States | clinicaltrials.gov |
Sponsors posting most
| Sponsor | New trials | Latest |
|---|---|---|
| Northern Jiangsu People's Hospital | 10 | September 10, 2026 |
| Assiut University | 4 | September 1, 2026 |
| The Second Affiliated Hospital of Chongqing Medical University | 4 | September 1, 2026 |
| Assistance Publique - Hôpitaux de Paris | 4 | April 28, 2026 |
| University of Michigan | 3 | September 15, 2026 |
| Institute of Liver and Biliary Sciences, India | 3 | July 20, 2026 |
| GlaxoSmithKline | 3 | July 15, 2026 |
| Hospices Civils de Lyon | 3 | June 15, 2026 |
| Shanghai Zhongshan Hospital | 3 | March 16, 2026 |
| Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 3 | December 15, 2025 |
| Pulmovant, Inc. | 2 | September 11, 2026 |
| Madrigal Pharmaceuticals, Inc. | 2 | August 13, 2026 |
| University Hospital Muenster | 2 | July 14, 2026 |
| General Hospital of Shenyang Military Region | 2 | June 16, 2026 |
| Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 2 | June 16, 2026 |
| Second Affiliated Hospital, Zhejiang University, School of Medicine | 2 | June 1, 2026 |
| Post Graduate Institute of Medical Education and Research, Chandigarh | 2 | January 7, 2026 |
| Central Hospital, Nancy, France | 2 | September 16, 2025 |
| Chinese University of Hong Kong | 2 | June 29, 2025 |
| M.D. Anderson Cancer Center | 2 | June 8, 2025 |
By phase
| Phase | New trials | Latest |
|---|---|---|
| Observational | 72 | November 5, 2026 |
| Not applicable | 58 | October 22, 2026 |
| Phase 2 | 18 | August 13, 2026 |
| Phase 4 | 10 | September 15, 2026 |
| Phase 3 | 9 | September 11, 2026 |
| Phase 1/2 | 3 | June 29, 2025 |
| Phase 1 | 1 | May 22, 2026 |
| Early phase 1 | 1 | May 5, 2026 |
By country
| Country | New trials | Latest |
|---|---|---|
| United States | 40 | October 9, 2026 |
| China | 33 | September 10, 2026 |
| France | 14 | October 22, 2026 |
| India | 8 | October 2, 2026 |
| Spain | 8 | August 31, 2026 |
| Canada | 6 | July 1, 2026 |
| Italy | 5 | June 16, 2026 |
| Turkey (Türkiye) | 5 | June 16, 2026 |
| United Kingdom | 5 | June 8, 2026 |
| Pakistan | 5 | April 27, 2026 |
| Germany | 4 | July 14, 2026 |
| Egypt | 4 | April 16, 2026 |
| Belgium | 3 | October 15, 2026 |
| Hong Kong | 3 | March 4, 2026 |
| Colombia | 2 | September 9, 2026 |
| Japan | 2 | July 15, 2026 |
| Taiwan | 2 | May 4, 2026 |
| Denmark | 2 | March 13, 2026 |
| Sweden | 2 | January 15, 2026 |
| Mexico | 2 | September 2, 2025 |
| Vietnam | 1 | November 5, 2026 |
| Romania | 1 | October 13, 2026 |
| Bangladesh | 1 | September 2, 2026 |
| Norway | 1 | August 20, 2026 |
| Austria | 1 | July 17, 2026 |
Where the register publishes
U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.