Data / New clinical trials / Dry Eye Syndromes

Dry Eye Syndromes trials: 235 new since Nov 2024

Name: New Dry Eye Syndromes clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Dry Eye Syndromes clinical trials: 235 rows for $11.75, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 10 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/dry-eye-syndromes, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 9, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

235 clinical studies in Dry Eye Syndromes were first posted on ClinicalTrials.gov from November 13, 2024 to November 9, 2026; 61 have an industry sponsor and 128 are recruiting or about to. The newest, NCT07926594, was posted on November 9, 2026: Effectiveness Study of TRYPTYR in Dry Eye Disease (Scott & Christie and Associates, PC).

The request: Every new Dry Eye Syndromes clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

235New trials
61Industry sponsored
128Recruiting or not yet
November 9, 2026Latest posted

Newest trials

The newest 100 of 235, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 9, 2026	NCT07926594	Effectiveness Study of TRYPTYR in Dry Eye Disease	Scott & Christie and Associates, PC	Observational	Recruiting	Dry Eye Disease	100	United States	clinicaltrials.gov
November 5, 2026	NCT07919223	Vitamin B Complex as Adjunct Therapy for Moderate-to-Severe Dry Eye Disease	Rania Fahmy	Not applicable	Completed	Dry Eye Disease, Dry Eye	56	Saudi Arabia	clinicaltrials.gov
November 3, 2026	NCT07911930	LacriFill Canalicular Occlusion for Dry Eye After LASIK	Mann Eye Institute	Not applicable	Not yet recruiting	Dry Eye Syndrome	75	United States	clinicaltrials.gov
November 2, 2026	NCT07908251	a Novel siRNA Eyedrops for DED Treatment	Eye & ENT Hospital of Fudan University	Early phase 1	Not yet recruiting	Dry Eye	30		clinicaltrials.gov
October 29, 2026	NCT07904728	Treating Contact Lens Discomfort With Cyclosporine 0.1% Ophthalmic Solution	Ocular Aesthetics, LLC dba Ocular Clinical Trials	Not applicable	Recruiting	Dry Eye Disease (DED), Contact Lens Discomfort (CLD)	50	United States	clinicaltrials.gov
October 29, 2026	NCT07902687	A Clinical Study to Evaluate the Safety and Effectiveness of MSCohi-O Lens in the Treatment of Immune-related Ocular Surface Diseases.	Guangdong ProCapZoom Biosciences Co., Ltd.	Phase 1	Not yet recruiting	Keratitis, Autoimmunity, Dry Eye Disease (DED)	20		clinicaltrials.gov
October 28, 2026	NCT07901647	Evaporative Dry Eye	Southern College of Optometry	Phase 4	Not yet recruiting	Dry Eye, Evaporative Dry Eye, Evaporative Dry Eye Disease	41	United States	clinicaltrials.gov
October 27, 2026	NCT07896395	20-20-20 Rule Plus Artificial Tears for Dry Eye	Zagazig University	Not applicable	Completed	Dry Eye	48	Egypt	clinicaltrials.gov
October 26, 2026	NCT07895849	Performance Evaluation of the OCUTOP Hand-held Corneal Topographer	University of Plymouth	Not applicable	Not yet recruiting	Corneal Topography, Dry Eye Syndromes, Keratoconus, Healthy Volunteers	150	United Kingdom	clinicaltrials.gov
October 22, 2026	NCT07888452	Cooling Eyedrops for Dry Eye	University of California, Berkeley	Phase 4	Not yet recruiting	Dry Eye	50	United States	clinicaltrials.gov
October 14, 2026	NCT07873931	A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases	Bristol-Myers Squibb	Phase 1	Not yet recruiting	Systemic Lupus Erythematosus, Sjögren's Disease, Rheumatoid Arthritis, Idiopathic Inflammatory Myopathies, Systemic...	60	Belgium, France, Germany, Netherlands, Poland, United States	clinicaltrials.gov
October 14, 2026	NCT07873697	Association Between Periodontitis and Dry Eye Disease: A Cross-Sectional Study	University of Sulaimani	Observational	Recruiting	Periodontitis, Dry Eye Disease (DED)	80	Iraq	clinicaltrials.gov
October 9, 2026	NCT07868965	Evaluation of Ophtholic Ultra for Ocular Surface Protection After Cataract Surgery	Kazakh Eye Research Institute	Phase 4	Active not recruiting	Dry Eye Disease (DED)	60	Kazakhstan	clinicaltrials.gov
October 1, 2026	NCT07852234	Exploratory Study on the Efficacy and Safety of Low-Dose Blinatumomab in the Treatment of Moderate to Severe Primary Sjögren's Syndrome	Beijing Tongren Hospital	Phase 2	Not yet recruiting	Primary Sjögren's Syndrome (pSS)	12	China	clinicaltrials.gov
September 30, 2026	NCT07849803	Effect of Acoltremon Ophthalmic Solution 0.003% on Tear Production and Symptoms in Patients With Tear Deficiency and Concurrent Neuropathic...	University of South Florida	Phase 4	Not yet recruiting	Ocular Pain, Dry Eye	28	United States	clinicaltrials.gov
September 30, 2026	NCT07848373	Contact Lens-Wearing Dry Eye Subjects Who Are Treated With Acoltremon 0.003%	Eye Research Associates, LLC	Phase 4	Not yet recruiting	Dry Eye, Contact Lens Discomfort, Eye Drops	50		clinicaltrials.gov
September 28, 2026	NCT07845357	Switching From Preserved Glaucoma Therapy to Preservative-Free ZOLYMBUS	Southern College of Optometry	Phase 4	Not yet recruiting	Eye Drops Self-instillation, Glaucoma, Dry Eye	40		clinicaltrials.gov
September 28, 2026	NCT07844408	Study of Eye Fatigue From Digital Screens and Its Impact on Visual Performance in People With Normal Vision and Myopia, With and Without...	Essilor International	Not applicable	Not yet recruiting	Myopia, Dry Eye Disease (DED)	120	France	clinicaltrials.gov
September 25, 2026	NCT07842536	Efficacy of Lycium Barbarum Polysaccharide in Dry Eye Disease Management	The Hong Kong Polytechnic University	Not applicable	Recruiting	Dry Eye Syndromes	30	Hong Kong	clinicaltrials.gov
September 25, 2026	NCT07841912	Ocular Surface Disease in Glaucoma Patients on Long-Term Therapy	Assiut University	Observational	Not yet recruiting	Glaucoma, Ocular Surface Disease, Dry Eye	55		clinicaltrials.gov
September 11, 2026	NCT07816419	Yogic Eye Exercises for Computer Vision Syndrome in Female Design Students	King Saud University	Not applicable	Completed	Computer Vision Syndrome, Asthenopia, Eye Strain, Dry Eye, Neck Pain, Shoulder Pain, Back Pain	36	Saudi Arabia	clinicaltrials.gov
September 9, 2026	NCT07810972	Evaluate the Safety and Efficacy of TJO-087	Taejoon Pharmaceutical Co., Ltd.	Phase 2	Active not recruiting	Dry Eye Syndrome (DES)	90	South Korea	clinicaltrials.gov
September 9, 2026	NCT07810569	Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients	Assiut University	Observational	Not yet recruiting	Meibomian Gland Dysfunction, Dry Eye Syndromes, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Sjogren's Syndrome...	150		clinicaltrials.gov
September 9, 2026	NCT07809022	Temporary Tear Duct Filling With Hyaluronic Acid Gel and Assessment of Dry Eye Disease (DED) After Bilateral Cataract Surgery	Medical University of Vienna	Phase 4	Not yet recruiting	Dry Eye, Dry Eye Disease (DED), Dry Eye Sensation After Cataract Surgery	25	Austria	clinicaltrials.gov
September 8, 2026	NCT07806240	Safety and Efficacy Study of RTP-008 (an Absorbable Tacrolimus Lacrimal Canalicular Plug) for Dry Eye	Zhejiang Raytone Bioscience Co.,Ltd	Not applicable	Completed	Dry Eye Disease (DED)	40	China	clinicaltrials.gov
September 1, 2026	NCT07796178	Evaluation of Lacrifill	Eye Research Associates, LLC	Phase 4	Recruiting	Dry Eye, Ocular Surface Disease, Cataract Surgery, Eyes Dry Feeling of	40	United States	clinicaltrials.gov
August 28, 2026	NCT07793344	Four-Week Ocular-Surface Evaluation of an Experimental Ophthalmic Liposomal Nanocarrier in Dry Eye Disease	Regional Specialist Hospital in Wroclaw	Not applicable	Completed	Dry Eye Disease	26	Poland	clinicaltrials.gov
August 27, 2026	NCT07790211	BL-RX01-TFSTAB-1402	Vance Thompson Vision	Phase 4	Recruiting	Dry Eye	20	United States	clinicaltrials.gov
August 27, 2026	NCT07789054	Ocular Surface Disease Index and Dry Eye Parameters in Hand Osteoarthritis	Medipol University	Observational	Completed	Dry Eye Syndrome (DES), Hand Osteoarthritis	23	Turkey (Türkiye)	clinicaltrials.gov
August 24, 2026	NCT07780890	A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases	Massachusetts General Hospital	Observational	Recruiting	Fuchs Endothelial Corneal Dysfunction, Open Angle Glaucoma (OAG), Dry Eye Disease (DED), Keratoconus, Lasik Eye Surgery	90	United States	clinicaltrials.gov
August 21, 2026	NCT07778888	BL1107 Response and Intensity Guided Dosing for Hyperemia Resolution Trial	Bausch & Lomb Incorporated	Phase 2	Not yet recruiting	Dry Eye Disease	20		clinicaltrials.gov
August 19, 2026	NCT07773740	Autologous Plasma Rich in Growth Factors for Severe Dry Eye Disease	Gladys Lucia Silva Linares	Not applicable	Not yet recruiting	Dry Eye Disease With Severe Keratitis	100		clinicaltrials.gov
August 17, 2026	NCT07768735	UNITY DX Cornea Study	Alcon Research	Observational	Recruiting	Tomography	110	United States	clinicaltrials.gov
August 10, 2026	NCT07753811	Effect of Oral Isotretinoin on Ocular Surface and Meibomian Glands	Benha University	Not applicable	Completed	Dry Eye Disease (DED), Meibomian Gland Dysfunction (Disorder), Acne Vulgaris	60	Egypt	clinicaltrials.gov
August 4, 2026	NCT07745062	The Effectiveness of Systane PRO Preservative Free Verses Blink Triple Care Preservative Free	Gordon Schanzlin New Vision	Phase 4	Recruiting	Dry Eye Disease (DED)	30	United States	clinicaltrials.gov
July 31, 2026	NCT07740564	Phase III Study of OT202 in Treating Moderate to Severe Dry Eye	Ocumension Therapeutics (Suzhou) Co., Ltd	Phase 3	Recruiting	Dry Eye	842	China	clinicaltrials.gov
July 28, 2026	NCT07732010	TRYPTYR as a Treatment for Patients With Dry Eye Disease (DED)	NYU Langone Health	Phase 4	Recruiting	Dry Eye Disease (DED)	50	United States	clinicaltrials.gov
July 23, 2026	NCT07722650	Twice-Daily Systane Complete Versus Four-Times-Daily Thealoz Duo for Dry Eye Disease	Instituto Internacional de Medicina y Terapia (IIMET)	Not applicable	Completed	Dry Eye Syndrome (DES), Ocular Surface Disease	120	Mexico	clinicaltrials.gov
July 23, 2026	NCT07722624	A Single Center, Open-Label Study to Evaluate the Ability of the TearScience™ LipiView™ II Ocular Surface Interferometer and the...	The Eye Care Institute	Phase 4	Active not recruiting	Dry Eye	20	United States	clinicaltrials.gov
July 20, 2026	NCT07715266	POST CATARACT SURGERY DRY EYE DISEASE	NOXELIS	Not applicable	Not yet recruiting	Dry Eye Disease (DED), Cataract Surgery	33	Spain	clinicaltrials.gov
July 15, 2026	NCT07706231	A Study of Full-Spectrum Screen Lighting for Reducing Screen-Related Eye Fatigue and Dry Eye	Zhongshan Ophthalmic Center, Sun Yat-sen University	Not applicable	Not yet recruiting	Visual Fatigue, Dry Eye, Computer Vision Syndrome	112	China	clinicaltrials.gov
July 15, 2026	NCT07705893	Treating Contact Lens Discomfort With Varenicline Solution Nasal Spray 0.03mg	Ocular Aesthetics, LLC dba Ocular Clinical Trials	Not applicable	Recruiting	Dry Eye	50	United States	clinicaltrials.gov
July 1, 2026	NCT07679685	Perfluorohexyloctane Eye Drops vs. Sodium Hyaluronate for Video Display Terminal-Associated Dry Eye	Beijing Tongren Hospital	Phase 4	Not yet recruiting	Dry Eye	159	China	clinicaltrials.gov
June 30, 2026	NCT07676084	Randomized Single Center Study to Evaluate Tolerability, Symptoms, and Visual Functional Outcomes With the Use of OTC Lubricating Eye Drops...	Andover Research Eye Institute	Phase 4	Recruiting	Dry Eye Disease (DED)	60	United States	clinicaltrials.gov
June 30, 2026	NCT07675460	Systemic Isotretinoin Therapy and Eye	Demet Mutlu	Not applicable	Completed	Dry Eye, Choroidal Thickness, Retinal Vascularisation, Acne Cystic, Isotretinoin	60	Turkey (Türkiye)	clinicaltrials.gov
June 26, 2026	NCT07671222	Safety and Efficacy of Topical Infliximab in Autoimmune Dry Eye Disease	Instituto de Oftalmología Fundación Conde de Valenciana	Phase 2	Not yet recruiting	Sjogren Syndrome, Sjogren Syndrome With Keratoconjunctivitis, Dry Eye Disease (DED)	38	Mexico	clinicaltrials.gov
June 22, 2026	NCT07659626	Long-term Effects of Acoltremon vs. Control in Dry Eye Disease	The Eye Care Institute	Observational	Recruiting	Dry Eye	60	United States	clinicaltrials.gov
June 18, 2026	NCT07657858	Effect of Dry Eye Treatment on Corneal Astigmatism Measurements	Jin Yang	Not applicable	Recruiting	Dry Eye, Cataract	400	China	clinicaltrials.gov
June 18, 2026	NCT07656688	Dose-Finding Study of HUC1-394 in Participants With Dry Eye Disease	Huons Co., Ltd.	Phase 2	Recruiting	Dry Eye Disease (DED)	150	South Korea	clinicaltrials.gov
June 16, 2026	NCT07650708	A Multicenter, Open-Label Study to Evaluate Perioperative Treatment of Dry Eye With Miebo® in Subjects Undergoing LASIK	Vance Thompson Vision	Phase 4	Recruiting	Dry Eye Syndrome (DES), Dry Eye Disease (DED)	100	United States	clinicaltrials.gov
June 11, 2026	NCT07640867	RCI001 Eye Drops 0.25% in Healthy Adult Male Participants	Rudacure	Phase 1	Completed	Dry Eye	40	South Korea	clinicaltrials.gov
June 10, 2026	NCT07639034	Effectiveness of Systane PRO for Mild to Moderate Dry Eye Disease	Gordon Schanzlin New Vision	Phase 4	Completed	Dry Eye Disease (DED)	33	United States	clinicaltrials.gov
June 9, 2026	NCT07635849	Randomized Clinical Trial of Artificial Tears With and Without Preservatives in Patients With Dry Eye Disease	Pokhara Academy of Health Sciences, Western Regional Hospital	Phase 4	Not yet recruiting	Dry Eye Disease (DED)	80	Nepal	clinicaltrials.gov
June 8, 2026	NCT07633938	The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial	Zhongshan Ophthalmic Center, Sun Yat-sen University	Not applicable	Not yet recruiting	Dry Eye Disease (DED), MGD-Meibomian Gland Dysfunction	142	China	clinicaltrials.gov
June 8, 2026	NCT07632534	Study of Proteomic Factors in Patients With Severe Dry Eye Syndrome Treated With Autologous Serum Eye Drops.	Centre Hospitalier Universitaire de Saint Etienne	Not applicable	Recruiting	Dry Eye Syndrome (DES), Dry Eye	68	France	clinicaltrials.gov
June 4, 2026	NCT07625124	A Phase 2 Study of RCI001 Ophthalmic Solution in Participants With Dry Eye Disease	Rudacure	Phase 2	Not yet recruiting	Dry Eye	200		clinicaltrials.gov
June 3, 2026	NCT07623382	Human Umbilical Cord Mesenchymal Stem Cell-derived Small Extracellular Vesicles for the Treatment of Dry Eye Disease	The First Affiliated Hospital of Xiamen University	Early phase 1	Recruiting	Dry Eye Disease, Umbilical Cord Mesenchymal Stem Cell-derived Small Extracellular Vesicles	20	China	clinicaltrials.gov
June 2, 2026	NCT07621952	Meibomian Gland Changes in Ocular Prosthesis Users	Instituto de Oftalmología Fundación Conde de Valenciana	Observational	Completed	Dry Eye, Meibomian Gland Dysfunction (Disorder), Anophthalmic Socket Syndrome, Ocular Prostheses	20	Mexico	clinicaltrials.gov
June 1, 2026	NCT07618364	The Effect of Rinsing on Ocular Inflammation and Symptoms in Patients With Dry Eye Disease	Rinsada	Not applicable	Recruiting	Dry Eye Syndromes, Dry Eye, Ocular Surface Disease	33	United States	clinicaltrials.gov
June 1, 2026	NCT07618169	Comparative Effects of USB-Powered Warm Compress and Self-Heating Eye Mask in the Management of Meibomian Gland Dysfunction	King Saud University	Not applicable	Completed	Dry Eye, MGD-Meibomian Gland Dysfunction	15	Saudi Arabia	clinicaltrials.gov
May 29, 2026	NCT07614347	Development and Evaluation of an Intelligent Diagnosis System for Dry Eye Disease Based on Confocal Microscopy	Capital Medical University	Observational	Not yet recruiting	Dry Eye	75		clinicaltrials.gov
May 26, 2026	NCT07606625	Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment	University of California, Berkeley	Phase 4	Recruiting	Dry Eye, Meibomian Gland Dysfunction	65	United States	clinicaltrials.gov
May 26, 2026	NCT07605572	Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity	Attikon Hospital	Observational	Recruiting	Dry Eye Disease (DED), Diabete Mellitus, GLP-1, Ocular Surface, Diabetes Type 2, Cornea	100	Greece	clinicaltrials.gov
May 18, 2026	NCT07593885	A Study to Evaluate the Performance and Safety of Artelac® Complete MDO® Versus VISMED® MULTI Eye Drops in the Management of Moderate to...	Dr. Gerhard Mann chem.-pharm. Fabrik GmbH	Not applicable	Recruiting	Dry Eye	160	Germany	clinicaltrials.gov
May 18, 2026	NCT07593404	Evaluation of a Novel Ocular Lubricating Eye Drop	Pleryon Therapeutics (Hangzhou) Limited	Not applicable	Recruiting	Dry Eye Syndrome (DES)	40	Canada	clinicaltrials.gov
May 14, 2026	NCT07588074	Tolerability Comparison of Flarex to Lotemax SM	Harrow Inc	Phase 4	Completed	Ocular Inflammation, Keratoconjunctivitis, Dry Eye Disease (DED), Post-operative Complications, Kerato Conjunctivitis...	40	United States	clinicaltrials.gov
May 12, 2026	NCT07581548	Evaluation of the Effectiveness of Three Tear Substitute Formulations in Postoperative Discomfort After Cataract Surgery	Democritus University of Thrace	Observational	Not yet recruiting	Cataract, Dry Eye	300	Greece	clinicaltrials.gov
May 11, 2026	NCT07579156	TearCare in Young Adults	University of Alabama at Birmingham	Not applicable	Not yet recruiting	Meibomian Gland Dysfunction (Disorder)	45	United States	clinicaltrials.gov
May 11, 2026	NCT07579130	Comparative Assessment of Lipid Layer Thickness Measurements	Indiana University	Observational	Recruiting	Dry Eye	50	United States	clinicaltrials.gov
May 5, 2026	NCT07566975	Real-World Assessment of VEVYE® for Short-Term Symptom and Sign Improvement of Dry Eye Disease in a Neuro-Ophthalmology Clinic: A 6-Month...	Neuro-Ophthalmology of Texas	Observational	Recruiting	Dry Eye	50	United States	clinicaltrials.gov
May 1, 2026	NCT07560735	Clinical Evaluation of Lifitegrast Ophthalmic Solution 5.0% in Dry Eye Disease Using In Vivo Confocal Microscopy	Toyos Clinic	Phase 4	Not yet recruiting	Dry Eye	30	United States	clinicaltrials.gov
April 28, 2026	NCT07554937	Blinking Exercise Study	St. Joseph's Healthcare Hamilton	Not applicable	Not yet recruiting	Dry Eye Disease (DED), Glaucoma	45		clinicaltrials.gov
April 28, 2026	NCT07554911	Detection and Optimization of Treatment of Severe Cases of Dry Eye Disease	Singapore National Eye Centre	Observational	Recruiting	Dry Eye	200	Singapore	clinicaltrials.gov
April 28, 2026	NCT07553455	Vevye + Flarex Combination Therapy for Dry Eye	Canyon City Eyecare	Phase 4	Enrolling by invitation	Dry Eye	60	United States	clinicaltrials.gov
April 27, 2026	NCT07551843	Comparative Effects of Autologous Serum, Umbilical Cord Blood-Derived Drops, and Platelet Lysate on Ocular Surface Parameters	G.Gennimatas General Hospital	Phase 1/2	Completed	Dry Eye Disease (DED)	80	Greece	clinicaltrials.gov
April 23, 2026	NCT07548632	A Clinical Study Evaluating Licaminlimab for Dry Eye Disease	Oculis	Phase 2/3	Active not recruiting	Dry Eye Disease (DED)	160	United States	clinicaltrials.gov
April 21, 2026	NCT07540884	Evaluation of Tears Naturale® Free and Tears Naturale® II Lubricant Eye Drops	Alcon Research	Not applicable	Completed	Dry Eye Disease	132	Canada	clinicaltrials.gov
April 14, 2026	NCT07529899	Evaluate the Efficacy and Safety of Amnion Membrane Disc Allograft vs Standard of Care in Participants With Dry Eye Disease	Cellution Biologics	Phase 4	Withdrawn	Dry Eye Disease (DED)	0		clinicaltrials.gov
April 13, 2026	NCT07525336	Effect of Dry Eye Disease on Accuracy of Intraocular Lens Power Calculation Before Phacoemulsification	Assiut University	Observational	Not yet recruiting	Dry Eye Disease (DED), Cataract (Post-operative Cataract Surgery Follow-up)	100		clinicaltrials.gov
April 13, 2026	NCT07524725	Effect of Behavioral Intervention (Baduanjin Alone or Laughter Exercise Plus Artificial Tears) Versus Artificial Tear on Dry Eye Disease: a...	Zhongshan Ophthalmic Center, Sun Yat-sen University	Not applicable	Not yet recruiting	Dry Eye Disease (DED)	540		clinicaltrials.gov
April 13, 2026	NCT07521748	A Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Profile of RC017 Ophthalmic Ointment Following Single and Multiple Doses...	Nanjing Reju Therapeutics Co., Ltd	Phase 1	Not yet recruiting	Dry Eye	24		clinicaltrials.gov
April 3, 2026	NCT07510620	Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses	Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists	Phase 4	Recruiting	Dry Eye	30	United States	clinicaltrials.gov
March 31, 2026	NCT07503886	An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease	Dompé Farmaceutici S.p.A	Phase 2	Recruiting	Dry Eye Disease (DED)	417	United States	clinicaltrials.gov
March 30, 2026	NCT07499193	Study of Blinking as a Function of Tear Film Quality	Essilor International	Not applicable	Not yet recruiting	Dry Eye	60	France	clinicaltrials.gov
March 24, 2026	NCT07490535	This is a Single Center, Open-label Prospective Study to Evaluate the Effect of Xiidra® (Lifitegrast Ophthalmic Solution 5.0%) on Tear Film...	Pittsburgh Research Institute	Phase 4	Not yet recruiting	Ocular Surface Disease, Dry Eye Syndrome (DES)	36	United States	clinicaltrials.gov
March 13, 2026	NCT07469865	Efficacy and Safety of 20% and 100% Autologous Serum Eye Drops in Patients With Severe Dry Eye Disease (AST)	University Hospital, Ghent	Not applicable	Completed	Dry Eye Disease	46	Belgium	clinicaltrials.gov
March 9, 2026	NCT07457021	A Study to Evaluate the Safety and Effectiveness of Perfluorohexyloctane Eye Drops on Treatment of Dry Eye Disease (DED) Related to...	Xiamen Ophthalmology Center Affiliated to Xiamen University	Observational	Not yet recruiting	Dry Eye Disease	2,000	China	clinicaltrials.gov
March 5, 2026	NCT07453212	Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction	Varol TUNALI	Not applicable	Enrolling by invitation	Dry Eye, Evaporative Dry Eye Disease, Meibomian Gland Dysfunction (Disorder)	130	Turkey (Türkiye)	clinicaltrials.gov
February 24, 2026	NCT07430735	BriTer Eyez Moisture Vue™ On-Demand Disposable Moisture Chamber	University of Rochester	Not applicable	Recruiting	Dry Eye Disease (DED)	35	United States	clinicaltrials.gov
February 24, 2026	NCT07430137	Blink Reminders and Meibomian Gland Loss in Digital Screen Users	Asociación para Evitar la Ceguera en México	Not applicable	Not yet recruiting	Dry Eye Syndromes, Meibomian Gland Dysfunction (Disorder)	28		clinicaltrials.gov
February 19, 2026	NCT07419776	The Effect Of Polycystic Ovarian Syndrome Treatment On Ocular Surface.	Cairo University	Observational	Completed	Poly Cystic Ovary Syndrome	90	Egypt	clinicaltrials.gov
February 17, 2026	NCT07415330	Lacrima VR for Dry Eye Disease and Meibomian Gland Dysfunction	Demaod Ltd	Not applicable	Not yet recruiting	Dry Eye, Dry Eye Syndromes	20		clinicaltrials.gov
February 17, 2026	NCT07413172	Autologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry Eye	University of Miami	Phase 2	Recruiting	Dry Eye, Eye Diseases, Eyes Dry Chronic	20	United States	clinicaltrials.gov
February 17, 2026	NCT07412860	Clinical Investigation Between the Topical Administration of a Tear Substitute With Ancillary Medicinal Substance and Hyaluronic Acid 0.3%...	FB Vision S.p.A	Not applicable	Recruiting	Dry Eye Syndromes, Dry Eye Disease (DED)	74	Italy	clinicaltrials.gov
February 12, 2026	NCT07407101	Impact of Filtration on Autologous Serum Eye Drops	University Hospital, Limoges	Not applicable	Completed	Dry Eye Syndrome (DES)	10	France	clinicaltrials.gov
February 9, 2026	NCT07397949	Rebamipide Versus Diquafosol for Perioperative Dry Eye in Cataract Surgery	Samsung Medical Center	Phase 4	Not yet recruiting	Dry Eye Disease (DED), Cataract	60	South Korea	clinicaltrials.gov
February 9, 2026	NCT07397936	Rebamipide Versus Diquafosol and Cyclosporine for Perioperative Dry Eye in Cataract Surgery	Samsung Medical Center	Phase 4	Completed	Dry Eye Disease (DED), Cataract	56	South Korea	clinicaltrials.gov
February 9, 2026	NCT07396441	Supplementary Kelulut Honey Therapy in Juvenile Open-Angle Glaucoma: Effects on IL-6, RNFL and Dry Eye	Universiti Sains Malaysia	Phase 4	Recruiting	Juvenile Open Angle Glaucoma, Dry Eye Disease (DED), Interleukin 6, Retinal Nerve Fiber Layer Thickness, HbA1c Level	60	Malaysia	clinicaltrials.gov
February 6, 2026	NCT07392307	Association Between Dry Eye Disease and Diabetic Macular Edema	Sohag University	Observational	Not yet recruiting	Dry Eye Disease (DED) , Diabetic Macular Edema	50	Egypt	clinicaltrials.gov
January 27, 2026	NCT07369375	Efficacy and Safety of VMX Eye Drops for Dry Eye Disease	VISUfarma SpA	Not applicable	Not yet recruiting	Dry Eye Disease (DED)	76		clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Superior University	8	April 6, 2025
Southern College of Optometry	7	October 28, 2026
Beijing Tongren Hospital	5	October 1, 2026
Assiut University	4	September 25, 2026
Vance Thompson Vision	4	August 27, 2026
Bausch & Lomb Incorporated	4	August 21, 2026
Cairo University	4	February 19, 2026
Second Affiliated Hospital, Zhejiang University, School of Medicine	4	January 14, 2026
Eye & ENT Hospital of Fudan University	3	November 2, 2026
The Hong Kong Polytechnic University	3	September 25, 2026
Alcon Research	3	August 17, 2026
Zhongshan Ophthalmic Center, Sun Yat-sen University	3	July 15, 2026
Instituto de Oftalmología Fundación Conde de Valenciana	3	June 26, 2026
Toyos Clinic	3	May 1, 2026
Singapore National Eye Centre	3	April 28, 2026
Grigore T. Popa University of Medicine and Pharmacy	3	January 12, 2026
Laboratoires Thea	3	November 18, 2025
China Medical University Hospital	3	August 21, 2025
Ocular Aesthetics, LLC dba Ocular Clinical Trials	2	October 29, 2026
University of California, Berkeley	2	October 22, 2026

By phase

Phase	New trials	Latest
Not applicable	95	November 5, 2026
Phase 4	54	October 28, 2026
Observational	37	November 9, 2026
Phase 2	23	October 1, 2026
Phase 3	11	July 31, 2026
Phase 1	6	October 29, 2026
Early phase 1	5	November 2, 2026
Phase 1/2	3	April 27, 2026
Phase 2/3	1	April 23, 2026

By country

Country	New trials	Latest
United States	60	November 9, 2026
China	27	October 1, 2026
Egypt	12	October 27, 2026
Taiwan	11	August 21, 2025
Pakistan	9	April 23, 2025
France	8	October 14, 2026
South Korea	8	September 9, 2026
Italy	7	February 17, 2026
Turkey (Türkiye)	6	August 27, 2026
Austria	5	September 9, 2026
Mexico	5	July 23, 2026
Spain	5	July 20, 2026
Hong Kong	4	September 25, 2026
Greece	4	May 26, 2026
Romania	4	January 12, 2026
Australia	4	November 20, 2025
Saudi Arabia	3	November 5, 2026
Germany	3	October 14, 2026
Poland	3	October 14, 2026
Canada	3	May 18, 2026
Singapore	3	April 28, 2026
Belgium	2	October 14, 2026
Netherlands	2	October 14, 2026
Malaysia	2	February 9, 2026
Croatia	2	May 25, 2025

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.