Data / New clinical trials / Cholangiocarcinoma

Cholangiocarcinoma trials: 147 new since Nov 2024

Name: New Cholangiocarcinoma clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Cholangiocarcinoma clinical trials: 147 rows for $7.35, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 5 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/cholangiocarcinoma, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 4, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

147 clinical studies in cholangiocarcinoma were first posted on ClinicalTrials.gov from November 13, 2024 to November 4, 2026; 21 have an industry sponsor and 119 are recruiting or about to. The newest, NCT07916870, was posted on November 4, 2026: Photodynamic Therapy Combined With a Self-expandable Radioactive Particle-loaded Biliary Stent for... (Zhai Wenlong).

The request: Every new Cholangiocarcinoma clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

147New trials
21Industry sponsored
119Recruiting or not yet
November 4, 2026Latest posted

Newest trials

The newest 100 of 147, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 4, 2026	NCT07916870	Photodynamic Therapy Combined With a Self-expandable Radioactive Particle-loaded Biliary Stent for Unresectable Extrahepatic...	Zhai Wenlong	Not applicable	Recruiting	Extrahepatic Cholangiocarcinoma	30	China	clinicaltrials.gov
November 4, 2026	NCT07916844	Hepatic Arterial Infusion Chemotherapy Versus Capecitabine as Adjuvant Therapy for Resected Biliary Tract Cancer	Zhai Wenlong	Phase 3	Not yet recruiting	Biliary Tract Cancer, Cholangiocarcinoma, Gallbladder Cancer	90	China	clinicaltrials.gov
October 14, 2026	NCT07873450	SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET	Full-Life Technologies UK Limited	Phase 1/2	Recruiting	Solid Tumor, NSCLC, Colorectal Cancer, Head and Neck Cancer, Cholangiocarcinoma	208	Australia, United States	clinicaltrials.gov
October 7, 2026	NCT07862998	A Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Advanced/Metastatic or Surgically Unresectable...	Incyte Corporation	Phase 2	Not yet recruiting	Unresectable Cholangiocarcinoma, Advanced/Metastatic Cholangiocarcinoma	72		clinicaltrials.gov
September 29, 2026	NCT07847710	Perioperative Retlirafusp Alfa(Anti-PD-L1/TGF-β Bifunctional Fusion Protein) Plus Famitinib and GEMOX-Based Hepatic Arterial Infusion...	The First Affiliated Hospital with Nanjing Medical University	Phase 2	Recruiting	Intrahepatic Cholangiocarcinoma (Icc), Neoadjuvant Therapy	81	China	clinicaltrials.gov
September 29, 2026	NCT07846267	Cryoablation Combined With Anlotinib Plus TQB2868 in Patients With Advanced Intrahepatic Cholangiocarcinoma	Fudan University	Phase 2	Not yet recruiting	Intrahepatic Cholangiocarcinoma	56	China	clinicaltrials.gov
September 25, 2026	NCT07841574	HAIC Plus QL1706 & Bevacizumab in Unresectable HER2-Negative ICC	Lianghe Lu	Phase 2	Recruiting	Intrahepatic Cholangiocarcinoma	35	China	clinicaltrials.gov
September 11, 2026	NCT07814586	Prognostic Evaluation and Systematic Re-Assessment of Cholangiocarcinoma Therapy	Karolinska University Hospital	Observational	Not yet recruiting	Intrahepatic Cholangiocarcinoma, Perihilar Cholangiocarcinoma	900		clinicaltrials.gov
August 28, 2026	NCT07793253	Phase 2 Study of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract Cancer	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Phase 2	Not yet recruiting	Biliary Tract Cancers, Intrahepatic Cholangiocarcinoma (Icc), Extrahepatic Cholangiocarcinoma, Gallbladder Carcinoma...	55	United States	clinicaltrials.gov
August 24, 2026	NCT07780838	Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma	Ohio State University Comprehensive Cancer Center	Phase 2	Recruiting	Locally Advanced Ampulla of Vater Carcinoma, Locally Advanced Biliary Tract Carcinoma, Locally Advanced Extrahepatic...	29	United States	clinicaltrials.gov
August 17, 2026	NCT07768085	Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT	Shengjing Hospital	Not applicable	Not yet recruiting	Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma, Cyst...	40,000	China	clinicaltrials.gov
August 14, 2026	NCT07766187	Combination Therapy Using Durvalumab and Histotripsy for Treatment of Intrahepatic Cholangiocarcinoma	University of Wisconsin, Madison	Phase 2	Recruiting	Intrahepatic Cholangiocarcinoma	12	United States	clinicaltrials.gov
August 14, 2026	NCT07765433	Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for...	ECOG-ACRIN Cancer Research Group	Phase 2/3	Not yet recruiting	Locally Advanced Biliary Tract Adenocarcinoma, Locally Advanced Extrahepatic Cholangiocarcinoma, Locally Advanced...	336		clinicaltrials.gov
August 12, 2026	NCT07760038	Protective Mechanisms of Phycocyanin in Partial Hepatectomy-Associated Liver Injury	Second Affiliated Hospital, Zhejiang University, School of Medicine	Not applicable	Recruiting	Intrahepatic Cholangiocarcinoma (Icc), Liver Injury	30	China	clinicaltrials.gov
August 12, 2026	NCT07760012	68Ga-SorB PET/CT Imaging in Patients With Solid Tumors	Peking University Third Hospital	Not applicable	Recruiting	Melanoma (Skin Cancer), Hepatocellular Carcinoma, Lung Cancer, Breast Cancer, Pancreatic Cancer, Ovarian Cancer...	50	China	clinicaltrials.gov
August 4, 2026	NCT07745296	Investigating Precision Medicine in the Adjuvant Setting in Biliary Tract Cancer	UNICANCER	Phase 3	Not yet recruiting	Biliary Tract Cancer (BTC)	990		clinicaltrials.gov
July 31, 2026	NCT07738939	IKS04 Regimen in Advanced Solid Tumors That Express CA242	Iksuda Therapeutics Ltd.	Phase 1	Not yet recruiting	Colorectal Cancer, Gastro Esophageal Junctional Cancer, Gastric Cancer (GC), GEJ Adenocarcinoma, PDAC - Pancreatic...	120	United States	clinicaltrials.gov
July 28, 2026	NCT07729917	Precision Integrated Strategies and Efficacy Evaluation for Biliary Tract Cancers: An Umbrella Platform Study	Zhejiang University	Phase 2	Not yet recruiting	Bile Duct Carcinoma, Cholangiocarcinoma	240	China	clinicaltrials.gov
July 21, 2026	NCT07717437	DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver...	Maastricht University Medical Center	Observational	Recruiting	Liver Cancer, Liver Metastases	350	Australia, Austria, Belgium, Canada, Germany, Netherlands, New Zealand, Norway...	clinicaltrials.gov
July 21, 2026	NCT07716345	Inter-Individual Tumor Heterogeneity on 3D-MRE for Predicting Response to Conversion Therapy in Liver Cancer	Second Affiliated Hospital of Xi'an Jiaotong University	Observational	Not yet recruiting	Hepato Cellular Carcinoma, Intrahepatic Bile Duct Carcinoma, Metastatic Hepatocellular Carcinoma	100		clinicaltrials.gov
July 21, 2026	NCT07715903	Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump...	National Cancer Institute (NCI)	Phase 1	Not yet recruiting	Colorectal Neoplasms, Neoplasms, Intrahepatic Cholangiocarcinoma, Adrenocortical Carcinoma, Metastasis, Neoplasm	20	United States	clinicaltrials.gov
July 20, 2026	NCT07714538	Breath Research Narrow Validation for Gastrointestinal Cancer Detection	Imperial College London	Observational	Recruiting	Oesophageal Squamous Cell Carcinoma, Oesophageal Adenocarcinoma, Gastric Adenocarcinoma, Pancreatic Ductal...	1,000	United Kingdom	clinicaltrials.gov
July 15, 2026	NCT07704216	Peritumoral MRE Stiffness for Predicting Resection Margin Status and Recurrence in Liver Cancer	Second Affiliated Hospital of Xi'an Jiaotong University	Observational	Not yet recruiting	Hepato Cellular Carcinoma, Intrahepatic Bile Duct Carcinoma, Metastatic Hepatocellular Carcinoma	150		clinicaltrials.gov
July 15, 2026	NCT07704021	Safety and Efficacy of EUS-guided Gallbladder Drainage Under Endoscopist-directed Conscious Sedation	Azienda Unita Sanitaria Locale di Piacenza	Observational	Completed	Cholecystitis, Acute, Pancreas Cancer, Duct Cell Adenocarcinoma, Cholangiocarcinoma	48	Italy	clinicaltrials.gov
July 9, 2026	NCT07691515	Intraarterial Therapies Plus Tislelizumab Plus Lenvatinib Versus Tislelizumab Plus Gemcitabine-Cisplatin in Unresectable Intrahepatic...	Zhejiang Cancer Hospital	Phase 3	Not yet recruiting	Intrahepatic Cholangiocarcinoma (Icc)	140	China	clinicaltrials.gov
June 29, 2026	NCT07673341	[18F]FTT Positron Emission Tomography/Computed Tomography to Predict Treatment Response in Patients Scheduled to Receive Gemcitabine...	University of Washington	Phase 2	Recruiting	Cholangiocarcinoma	22	United States	clinicaltrials.gov
June 22, 2026	NCT07658586	AI Multimodal Model for Liver Cancer Diagnosis and Prognosis	Guangxi Medical University	Observational	Active not recruiting	Liver Cancer, Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma (Icc)	600	China	clinicaltrials.gov
June 15, 2026	NCT07646717	Efficacy and Safety of HAIC Combined With Lenvatinib and PD-1 Inhibitors for Advanced Intrahepatic Cholangiocarcinoma	Tianjin Medical University Cancer Institute and Hospital	Phase 2	Active not recruiting	Intrahepatic Cholangiocarcinoma (Icc)	30	China	clinicaltrials.gov
June 12, 2026	NCT07645742	Pilot Study of Intermittent Fasting With Immune Checkpoint Inhibitors	West Virginia University	Not applicable	Not yet recruiting	Cancer (Advanced Stage)	90		clinicaltrials.gov
June 11, 2026	NCT07641036	Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer	Beijing Biotech	Phase 1/2	Recruiting	Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma, Extrahepatic Cholangiocarcinoma, Gallbladder Carcinoma, Biliary...	30	China	clinicaltrials.gov
June 10, 2026	NCT07640048	Adjuvant Therapy for High-Risk Intrahepatic Cholangiocarcinoma: A Real-World Study	Peking Union Medical College Hospital	Observational	Recruiting	Intrahepatic Cholangiocarcinoma (Icc)	90	China	clinicaltrials.gov
June 9, 2026	NCT07636824	Efficacy and Safety of Postoperative Concurrent Chemoradiotherapy for Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma: A...	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Phase 2	Recruiting	Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma	92	China	clinicaltrials.gov
June 8, 2026	NCT07632235	A Multicenter, Prospective, Randomized, Open-label Phase Ib/II Study of Celecoxib Plus Pembrolizumab and Gemcitabine/Cisplatin Versus...	Shanghai 6th People's Hospital	Phase 1/2	Not yet recruiting	Intrahepatic Cholangiocarcinoma (Icc)	112	China	clinicaltrials.gov
June 3, 2026	NCT07623642	A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or...	GV20 Therapeutics	Phase 2	Not yet recruiting	Uterine Cervical Neoplasms, Triple Negative Breast Neoplasms, Prostatic Neoplasms, Squamous Cell Carcinoma of Head and...	227	China	clinicaltrials.gov
June 2, 2026	NCT07620080	EYEMAX® Versus SPYGLASS™ DS for Biliary Stricture Diagnosis	David KARSENTI	Not applicable	Not yet recruiting	Cholangiocarcinoma, Biliary Stricture	120		clinicaltrials.gov
June 2, 2026	NCT07619937	Efficacy and Safety of Hepatic Arterial Infusion Chemotherapy Combined With Tislelizumab and Regorafenib as First-Line Therapy for Advanced...	The First Affiliated Hospital of Zhengzhou University	Phase 2	Completed	Cholangiocarcinoma	31	China	clinicaltrials.gov
June 2, 2026	NCT07619313	AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or...	Jonsson Comprehensive Cancer Center	Phase 1	Recruiting	Borderline Resectable Pancreatic Ductal Adenocarcinoma, Locally Advanced Cholangiocarcinoma, Locally Advanced...	46	United States	clinicaltrials.gov
May 29, 2026	NCT07614061	Safety and Efficacy of CD160-Enhanced Autologous Antigen-Specific T-Cells (BTC-Ag-T) in Advanced Biliary Tract Cancer	Shanghai Zhongshan Hospital	Phase 1	Recruiting	Biliary Tract Neoplasms, Cholangiocarcinoma, Intrahepatic, Cholangiocarcinoma, Extrahepatic, Cholangiocarcinoma...	18	China	clinicaltrials.gov
May 20, 2026	NCT07598318	Study of Becotatug Vedotin Added to Standard Treatment for Advanced Bile Duct Cancer With EGFR Mutations	Sir Run Run Shaw Hospital	Phase 2/3	Not yet recruiting	Cholangiocarcinoma	164		clinicaltrials.gov
May 19, 2026	NCT07594964	To Evaluate the Safety, Tolerability, and Preliminary Efficacy of XH001 Injection as Adjuvant Therapy in Patients With High-risk Recurrent...	Shenzhen Xinhe Biomedical	Phase 1	Recruiting	Biliary Cancer (Cholangiocarcinoma, Gall Bladder Cancer), Pancreatic Ductal Adenocarcinoma (PDAC), Hepatocellular...	48	China	clinicaltrials.gov
May 18, 2026	NCT07594067	TCR1188-ABC Cells in KRAS-mutated Cancers	University of Pennsylvania	Phase 1	Recruiting	Cholangiocarcinoma, Colorectal Cancer, Non-Small Cell Lung Cancer, Pancreatic Adenocarcinoma	30	United States	clinicaltrials.gov
May 6, 2026	NCT07570849	Chidamide Combined With Chemotherapy and Immunotherapy as First-line Treatment for Advanced Intrahepatic Cholangiocarcinoma	Shanghai Zhongshan Hospital	Phase 2	Recruiting	Intrahepatic Cholangiocarcinoma	35	China	clinicaltrials.gov
May 1, 2026	NCT07561775	Adebrelimab Plus S-1 for Resected Cholangiocarcinoma	Xingjun Guo	Phase 2	Not yet recruiting	Cholangiocarcinoma, Biliary Tract Cancer	40		clinicaltrials.gov
April 30, 2026	NCT07558304	Suprapapillary Metal Stent vs. Routine Transpapillary Drainage in Malignant Hilar Biliary Obstruction (SMART-B Trial)	Hospital de Clinicas de Porto Alegre	Not applicable	Recruiting	Cholangiocarcinoma, Bile Duct Neoplasms, Malignant Biliary Obstruction	84	Brazil	clinicaltrials.gov
April 29, 2026	NCT07557225	18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors	Peking University First Hospital	Not applicable	Recruiting	Clear Cell Renal Cell Cancer (ccRCC), Urothelial Carcinoma (UC), Colorectal Cancer, Cervical Cancer, Ovarian Cancer...	200	China	clinicaltrials.gov
April 29, 2026	NCT07556835	Outcomes After Liver and Biliary Resection at a High-Volume Center	Azienda USL Toscana Centro	Observational	Not yet recruiting	Liver Neoplasms, Hepatobiliary Diseases, Cholangiocarcinoma, Hepatocellular Carcinoma, Liver Metastases From Colorectal...	1,000	Italy	clinicaltrials.gov
April 13, 2026	NCT07522476	A Clinical Study to Evaluate the Efficacy and Safety of VG2025 in Intrahepatic Cholangiocarcinoma	Virogin Biotech Ltd.	Phase 2	Recruiting	Intrahepatic Cholangiocarcinoma	30	China	clinicaltrials.gov
April 7, 2026	NCT07514533	The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced Cholangiocarcinoma	Sir Run Run Shaw Hospital	Phase 2	Not yet recruiting	Cholangiocarcinoma	60		clinicaltrials.gov
March 23, 2026	NCT07488676	A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors	Astellas Pharma Global Development, Inc.	Phase 1/2	Recruiting	Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma	150	Japan, United States	clinicaltrials.gov
March 20, 2026	NCT07486713	Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies	Rigel Pharmaceuticals	Phase 4	Recruiting	AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma, Solid Tumor Malignancies	16	United States	clinicaltrials.gov
March 18, 2026	NCT07479264	A Study on Intratumoral Fibrosis and α-SMA Expression in Intrahepatic Cholangiocarcinoma	First Affiliated Hospital, Sun Yat-Sen University	Observational	Completed	Intrahepatic Cholangiocarcinoma (Icc)	169	China	clinicaltrials.gov
March 17, 2026	NCT07478523	FAPI-PET Value for the Initial Screening of Pancreatic and Biliary Cancers	University Hospital, Bordeaux	Phase 2	Recruiting	Cholangiocarcinoma, Pancreatic Adenocarcinoma	120	France	clinicaltrials.gov
March 17, 2026	NCT07476651	Scout Dose of Resin Microspheres	Seoul National University Hospital	Not applicable	Recruiting	Radioembolization, Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (ICC), Liver Metastasis	30	South Korea	clinicaltrials.gov
March 9, 2026	NCT07458347	A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral...	Kestrel Therapeutics, Inc.	Phase 1	Recruiting	KRAS-mutant Non-small Cell Lung Cancer (NSCLC), KRAS-mutant Pancreatic Ductal Adenocarcinoma (PDAC), KRAS-mutant...	545	United States	clinicaltrials.gov
March 6, 2026	NCT07454486	TRACE-BTC. Relation of Biomarkers and Patients Reported Quality of Life to Outcomes in Patients With Biliary Tract Cancer: a Real- World...	Aarhus University Hospital	Observational	Not yet recruiting	Biliary Tract Cancer (BTC), Biliary Tract Cancer (CCA), Gall Bladder Cancer, Biliary Tract Cancers (BTC)...	300	Denmark	clinicaltrials.gov
February 25, 2026	NCT07432568	A Study of Liposomal Irinotecan Plus 5-FU/LV HAIC With Lenvatinib and a PD-1 Inhibitor in Advanced ICC	Tianjin Medical University Cancer Institute and Hospital	Phase 2	Not yet recruiting	Intrahepatic Cholangiocarcinoma	30		clinicaltrials.gov
February 10, 2026	NCT07401485	Preclinical Development of a 3D Bili-MRI Reconstruction Tool and an Artificial Intelligence Algorithm to Assist Endoscopists in Performing...	Assistance Publique - Hôpitaux de Paris	Observational	Not yet recruiting	Patients With Biliary Stricture Treated During ERCP With Available MRCP and Abdominal CT Scan	100	France	clinicaltrials.gov
January 22, 2026	NCT07359586	Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia	Zhejiang University	Observational	Recruiting	Gastric Cancer, Hepatic Carcinoma, Pulmonary Carcinoma, Pancreatic Carcinoma, Cholangiocarcinoma, Thyroid Carcinoma	1,200	China	clinicaltrials.gov
January 20, 2026	NCT07353827	FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma	Sun Yat-sen University	Phase 2	Not yet recruiting	Intrahepatic Cholangiocarcinoma (Icc), Hepatic Arterial Infusion Chemotherapy	36	China	clinicaltrials.gov
January 15, 2026	NCT07344116	Hepatobiliary and Pancreatic Tumor Biobank	Second Affiliated Hospital, Zhejiang University, School of Medicine	Observational	Not yet recruiting	Hepotacellular Carcinoma, Cholangiocarcinoma, Pancreatic Cancer	300		clinicaltrials.gov
January 13, 2026	NCT07337850	Prospective Evaluation of 68Ga-FAPI PET in Biliary Cancers	Tata Memorial Centre	Observational	Recruiting	Gall Bladder Cancer, Intrahepatic Cholangiocarcinoma (Icc)	60	India	clinicaltrials.gov
January 13, 2026	NCT07337525	A First in Human Study of PLT012 in Participants With Solid Tumor Cancers	Pilatus Biosciences Inc	Phase 1	Recruiting	Advanced Malignant Solid Tumor, Solid Tumor Cancer	36	United States	clinicaltrials.gov
January 12, 2026	NCT07334119	Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-304 in Adults With Advanced HER2-Expressing Solid Tumors	Myeloid Therapeutics	Phase 1	Recruiting	HER2-Expressing Solid Tumors	60	Australia	clinicaltrials.gov
January 9, 2026	NCT07328919	Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma...	TransThera Sciences (Nanjing), Inc.	Phase 3	Not yet recruiting	Intrahepatic Cholangiocarcinoma (Icc), Advanced Cholangiocarcinoma	138	China	clinicaltrials.gov
January 6, 2026	NCT07319767	Comparing the TDTP-RECIST With RECIST 1.1 and Other Volumetric Evaluation Methods for Assessing the Therapeutic Efficacy of Irregular...	Shanghai Zhongshan Hospital	Observational	Completed	Breast Cancer, Pancreatic Adenocarcinoma (Ductal Adenocarcinoma), Biliary Cancer (Cholangiocarcinoma, Gall Bladder...	120	China	clinicaltrials.gov
December 26, 2025	NCT07304388	HAIC Plus Systemic Chemotherapy, Lenvatinib and Toripalimab in Advanced ICC	Sun Yat-sen University	Phase 2	Completed	Intrahepatic Cholangiocarcinoma (Icc)	96	China	clinicaltrials.gov
December 22, 2025	NCT07296666	Adjuvant Chemotherapy for BTC Based on 3D-PTA	Fudan University	Phase 2	Not yet recruiting	Cholangiocarcinoma	98		clinicaltrials.gov
December 18, 2025	NCT07291947	PULSAR Combined With Immunotherapy and Chemotherapy	Wang Xin	Phase 1/2	Recruiting	Cholangiocarcinoma	60	China	clinicaltrials.gov
December 18, 2025	NCT07291063	Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA	Shanghai Zhongshan Hospital	Observational	Recruiting	Cholangiocarcinoma	50	China	clinicaltrials.gov
December 15, 2025	NCT07282912	Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut...	Yale University	Phase 2	Recruiting	Foregut Adenocarcinoma, Esophageal Adenocarcinoma, Gastroesophageal Adenocarcinoma, Gastric Adenocarcinoma, Pancreas...	54	United States	clinicaltrials.gov
December 8, 2025	NCT07269158	A Phase IIb Randomized Clinical Trial of Immune Checkpoint Inhibitor-based Maintenance Therapy in Patients With Advanced Biliary Tract...	Yonsei University	Phase 1/2	Not yet recruiting	Biliary Tract Neoplasms, Advanced Cancer, Immunotherapy	160	South Korea	clinicaltrials.gov
December 5, 2025	NCT07265674	A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best...	J-Pharma Co., Ltd.	Phase 3	Recruiting	Advanced Biliary Tract Cancer, Biliary Tract Cancer (BTC)	480	United States	clinicaltrials.gov
December 4, 2025	NCT07263217	Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver Injury	Second Affiliated Hospital, Zhejiang University, School of Medicine	Not applicable	Recruiting	Cholangiocarcinoma	30	China	clinicaltrials.gov
December 3, 2025	NCT07260175	Phase II Study Evaluating Ivosidenib Maintenance After SOC Adjuvant Chemotherapy in Curative mIDH1 Cholangiocarcinoma	Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest	Phase 2	Recruiting	Cholangiocarcinoma, IDH Mutation	40	Germany	clinicaltrials.gov
November 19, 2025	NCT07235007	Repeated Endobiliary Radiofrequency Ablation Plus Durvalumab, Gemcitabine, and Cisplatin for Unresectable Extrahepatic Cholangiocarcinoma	Aichi Medical University	Not applicable	Recruiting	Extrahepatic Cholangiocarcinoma	120	Japan, South Korea	clinicaltrials.gov
November 6, 2025	NCT07225452	An Exosomal miRNA-based Liquid Biopsy for ICC Detection	City of Hope Medical Center	Observational	Completed	Intrahepatic Cholangiocarcinoma (Icc)	535	United States	clinicaltrials.gov
November 5, 2025	NCT07224750	A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer	City of Hope Medical Center	Observational	Recruiting	Hepatocellular Carcinoma (HCC), Cholangiocarcinoma, Pancreatic Ductal Adenocarcinoma (PDAC), Esophageal Squamous Cell...	1,000	United States	clinicaltrials.gov
November 5, 2025	NCT07224737	Liquid Biopsy Using Exosomal miRNA Enables Risk Stratification of Potential Metastasis in Patients With Intrahepatic Cholangiocarcinoma.	City of Hope Medical Center	Observational	Completed	Intrahepatic Cholangiocarcinoma (Icc)	230	United States	clinicaltrials.gov
November 4, 2025	NCT07224464	The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.	New Phase Ltd.	Not applicable	Recruiting	Metastatic Solid Tumors, Stage 4 Cancer	12	United States	clinicaltrials.gov
October 31, 2025	NCT07223307	REGULUS: MRI-guided Adaptive SABR for Liver Cancers	Stanford University	Phase 2	Recruiting	Liver Cancer, Intrahepatic Cholangiocarcinoma, Liver Metastases, HCC	62	United States	clinicaltrials.gov
October 9, 2025	NCT07213791	A Study of LY4337713 in Participants With FAP-Positive Solid Tumors	Eli Lilly and Company	Phase 1	Recruiting	Ovarian Neoplasms, Breast Neoplasms, Pancreatic Intraductal Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms...	340	China, Germany, Japan, Netherlands, United States	clinicaltrials.gov
October 6, 2025	NCT07208526	A Randomized Trial of Surgical Decision-Making Guided by TDTP-RECIST	Shanghai Zhongshan Hospital	Not applicable	Not yet recruiting	Intrahepatic Cholangiocarcinoma (Icc), Conversion Therapy, TDTP-RECIST, GOLP Regimen	270	China	clinicaltrials.gov
October 3, 2025	NCT07206355	In-Depth Characterisation of Biliary Strictures and Hepato-Pancreato-Biliary Focal Lesions for Development of New Technologies to Tackle...	University of Nottingham	Observational	Recruiting	Biliary Tract Cancer (BTC), Biliary Tract Cancer (CCA), Cholangiocarcinoma, Cholangiocarcinoma Cancer, Cholangio...	160	United Kingdom	clinicaltrials.gov
October 1, 2025	NCT07201519	Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy	Michael J Cavnar, MD	Phase 2	Recruiting	Colorectal Cancer Metastatic, Intrahepatic Cholangiocarcinoma	80	United States	clinicaltrials.gov
September 16, 2025	NCT07176962	A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers Screening	Yingbin Liu, MD, PhD, FACS	Observational	Recruiting	Gall Bladder Cancer, Intrahepatic Cholangiocarcinoma (Icc), Extrahepatic Cholangiocarcinoma, Hilar Cholangiocarcinoma...	1,800	China	clinicaltrials.gov
September 12, 2025	NCT07169734	A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors	Alentis Therapeutics AG	Phase 1/2	Recruiting	Cervical Squamous Cell Carcinoma, Squamous Non-small-cell Lung Cancer, Colorectal Cancer, Intrahepatic...	180	France, Hong Kong, Italy, Netherlands, Singapore, Spain, Taiwan, United States	clinicaltrials.gov
September 9, 2025	NCT07161869	Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)	Erasmus Medical Center	Observational	Recruiting	Hilar Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma (Icc), Cholangiocarcinoma, Perihilar Cholangiocarcinoma...	250	Netherlands	clinicaltrials.gov
September 4, 2025	NCT07155525	Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas	Minia University	Not applicable	Recruiting	Pancreatic Cancer, Periampullary Cancer, Duodenal Cancer, Cholangiocarcinoma, Pancreatic Ductal Adenocarcinoma...	194	Egypt	clinicaltrials.gov
September 4, 2025	NCT07153783	Interventional AI-Human Collaboration for Liver Tumor Diagnosis	Shengjing Hospital	Not applicable	Completed	Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma, Cyst...	10,333	China	clinicaltrials.gov
August 28, 2025	NCT07146646	Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer	Case Comprehensive Cancer Center	Phase 2	Suspended	Biliary Tract Cancer, Biliary Tract Neoplasms, Cholangiocarcinoma, Gallbladder Cancer, Gallbladder Carcinoma	27	United States	clinicaltrials.gov
August 17, 2025	NCT07128290	PErioperative CISGEM + Rilvegostomig in High-Risk Resectable Intra Hepatic CholangioCarcinoma	Federation Francophone de Cancerologie Digestive	Phase 2	Not yet recruiting	Intrahepatic Cholangiocarcinoma (Icc)	49	France	clinicaltrials.gov
August 12, 2025	NCT07118176	Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers	Jonsson Comprehensive Cancer Center	Phase 1	Active not recruiting	Anal Carcinoma, Bladder Carcinoma, Breast Carcinoma, Cervical Carcinoma, Cholangiocarcinoma, Colorectal Carcinoma...	30	United States	clinicaltrials.gov
August 11, 2025	NCT07115420	Improving a Bile Duct Drainage Procedure in Patients With Inoperable Cancer Blocking the Bile Ducts: Comparing Two Types of Endoscopically...	Waikato Hospital	Not applicable	Not yet recruiting	Malignant Biliary Obstruction, Advanced Pancreatic Cancer and Cholangiocarcinoma, Inoperable Malignant Biliary...	100	New Zealand	clinicaltrials.gov
August 6, 2025	NCT07106827	A Study of GV20-0251 in Advanced or Refractory Solid Tumors	West China Hospital	Phase 1	Recruiting	HCC - Hepatocellular Carcinoma, Cholangiocarcinoma, Melanoma, NSCLC (Non-small Cell Lung Cancer), Pancreatic Ductal...	10	China	clinicaltrials.gov
August 6, 2025	NCT07105852	Exploring the Safety and Efficacy of Sacituzumab Tirumotecan Combined With Pucotenlimab in the Treatment of Advanced Cholangiocarcinoma	Sir Run Run Shaw Hospital	Phase 2	Recruiting	Cholangiocarcinoma	59	China	clinicaltrials.gov
August 3, 2025	NCT07101237	An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Characterization of Tumor...	Peking Union Medical College Hospital	Observational	Recruiting	Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (ICC), Primary Liver Cancer	308	China	clinicaltrials.gov
July 17, 2025	NCT07070700	Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahepatic Cholangiocarcinoma	Fudan University	Phase 2	Recruiting	Intrahepatic Cholangiocarcinoma (Icc)	56	China	clinicaltrials.gov
July 14, 2025	NCT07064447	Spanish Registry of Direct Cholangiopancreatoscopy by Single Operator	Germans Trias i Pujol Hospital	Observational	Not yet recruiting	Cholangiocarcinoma, Cholangiopathy, Biliary Stricture, Choledocholithiasis, Pancreatic Cancer	260		clinicaltrials.gov
July 14, 2025	NCT07063888	A Prospective Phase II Study of Postoperative Concurrent Chemoradiotherapy in Patients With Intrahepatic Cholangiocarcinoma	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Phase 2	Recruiting	Intrahepatic Cholangiocarcinoma (Icc), Adjuvant Chemoradiotherapy, Narrow Margin, Lymph Node Involvement	66	China	clinicaltrials.gov
June 29, 2025	NCT07043387	Streamlining Radioembolization for CCC and Metastatic Liver Cancer	Seoul National University Hospital	Observational	Recruiting	Metastatic Colorectal Carcinoma (mCRC), Metastatic Liver Cancer, Cholangiocarcinoma	60	South Korea	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Shanghai Zhongshan Hospital	6	May 29, 2026
Second Affiliated Hospital, Zhejiang University, School of Medicine	4	August 12, 2026
Tianjin Medical University Cancer Institute and Hospital	4	June 15, 2026
Fudan University	3	September 29, 2026
Sir Run Run Shaw Hospital	3	May 20, 2026
Seoul National University Hospital	3	March 17, 2026
City of Hope Medical Center	3	November 6, 2025
Zhai Wenlong	2	November 4, 2026
Shengjing Hospital	2	August 17, 2026
Zhejiang University	2	July 28, 2026
Second Affiliated Hospital of Xi'an Jiaotong University	2	July 21, 2026
National Cancer Institute (NCI)	2	July 21, 2026
Imperial College London	2	July 20, 2026
Peking Union Medical College Hospital	2	June 10, 2026
Cancer Institute and Hospital, Chinese Academy of Medical Sciences	2	June 9, 2026
The First Affiliated Hospital of Zhengzhou University	2	June 2, 2026
Jonsson Comprehensive Cancer Center	2	June 2, 2026
University Hospital, Bordeaux	2	March 17, 2026
Assistance Publique - Hôpitaux de Paris	2	February 10, 2026
Sun Yat-sen University	2	January 20, 2026

By phase

Phase	New trials	Latest
Phase 2	45	October 7, 2026
Observational	43	September 11, 2026
Not applicable	25	November 4, 2026
Phase 1	14	July 31, 2026
Phase 1/2	10	October 14, 2026
Phase 3	5	November 4, 2026
Phase 2/3	4	August 14, 2026
Phase 4	1	March 20, 2026

By country

Country	New trials	Latest
China	56	November 4, 2026
United States	36	October 14, 2026
France	11	March 17, 2026
Italy	9	July 15, 2026
Netherlands	7	July 21, 2026
Australia	5	October 14, 2026
United Kingdom	5	July 21, 2026
South Korea	5	March 17, 2026
Germany	4	July 21, 2026
Spain	4	July 21, 2026
Canada	3	July 21, 2026
Sweden	3	July 21, 2026
Japan	3	March 23, 2026
Taiwan	3	September 12, 2025
Austria	2	July 21, 2026
Belgium	2	July 21, 2026
New Zealand	2	July 21, 2026
Norway	2	July 21, 2026
Switzerland	2	July 21, 2026
Brazil	1	April 30, 2026
Denmark	1	March 6, 2026
India	1	January 13, 2026
Hong Kong	1	September 12, 2025
Singapore	1	September 12, 2025
Egypt	1	September 4, 2025

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.