Data / New clinical trials / Bipolar Disorder

Bipolar Disorder trials: 165 new since Nov 2024

Name: New Bipolar Disorder clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Bipolar Disorder clinical trials: 165 rows for $8.25, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 7 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (sponsor class, condition groups (MeSH), interventions, start date, enrollment type, location countries and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/bipolar-disorder, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 6, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

165 clinical studies in Bipolar Disorder were first posted on ClinicalTrials.gov from November 13, 2024 to November 6, 2026; 18 have an industry sponsor and 121 are recruiting or about to. The newest, NCT07921966, was posted on November 6, 2026: Pharmacokinetics and Relative Bioavailability of Intranasal vs Intramuscular Olanzapine in Healthy Adult... (Neurelis, Inc.).

The request: Every new Bipolar Disorder clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

165New trials
18Industry sponsored
121Recruiting or not yet
November 6, 2026Latest posted

Newest trials

The newest 100 of 165, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 6, 2026	NCT07921966	Pharmacokinetics and Relative Bioavailability of Intranasal vs Intramuscular Olanzapine in Healthy Adult Participants	Neurelis, Inc.	Phase 1	Not yet recruiting	Healthy Adult Participants	24		clinicaltrials.gov
November 6, 2026	NCT07921667	Sleep Monitoring for Early Detection of Relapse in People With Schizophrenia or Bipolar Disorder Receiving Usual Treatment	International University of La Rioja	Observational	Not yet recruiting	Bipolar Disorder (BD), SCHIZOPHRENIA 1 (Disorder)	30	Spain	clinicaltrials.gov
November 5, 2026	NCT07920302	Affective Cognitive Training in Mood Disorders and High-risk Relatives	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	Not applicable	Recruiting	Major Depressive Disorder (MDD), Bipolar Disorder (BD)	100	Denmark	clinicaltrials.gov
November 3, 2026	NCT07913542	N-Acetylcysteine for Bipolar and Alcohol Use Disorders	Medical University of South Carolina	Phase 2	Not yet recruiting	Bipolar Disorder, Alcohol Use Disorder	70	United States	clinicaltrials.gov
November 2, 2026	NCT07910318	Neurostructural and Biochemical Signatures of Tobacco Smoking in Mood Disorders	Assiut University	Observational	Not yet recruiting	Major Depressive Disorder, Bipolar Disorder, Tobacco Use Disorder, Mood Disorders	240		clinicaltrials.gov
October 29, 2026	NCT07905378	Validation of Wearable Core Body Temperature-Based Circadian Rhythm Digital Biomarkers	Korea University Anam Hospital	Observational	Not yet recruiting	Mood Disorders, Major Depressive Diorder, Bipolar Disorders, Mental Disorder	200		clinicaltrials.gov
October 29, 2026	NCT07903246	A Prospective Study of Anxiety, Depression, and Bipolar Disorder in People	Second Affiliated Hospital, Zhejiang University, School of Medicine	Observational	Recruiting	Anxiety Disorders, Depressive Disorder, Bipolar Disorder (BD)	2,690	China	clinicaltrials.gov
October 22, 2026	NCT07890805	Evaluating the PolarUs App in People With Bipolar Disorder	University of British Columbia	Not applicable	Not yet recruiting	Bipolar Disorder (BD), Quality of Life (QOL)	504	Canada	clinicaltrials.gov
October 19, 2026	NCT07881016	French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism...	Fondation FondaMental	Not applicable	Recruiting	Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP), Bipolar Disorder (BD), Major Depressive...	3,000	France	clinicaltrials.gov
October 19, 2026	NCT07880015	Digital Phenotypes for Predicting Depression_Validation	Korea University Anam Hospital	Observational	Enrolling by invitation	Major Depressive Disorder, Bipolar I Disorder, Bipolar II Disorder, Mood Disorders	200	South Korea	clinicaltrials.gov
October 16, 2026	NCT07879131	A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness	Alexandria University	Not applicable	Not yet recruiting	Severe Mental Illness, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Major Depressive Disorder	60	Bahrain	clinicaltrials.gov
October 16, 2026	NCT07879118	Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental Illness	Biruni University	Not applicable	Not yet recruiting	Schizophenia Disorder, Severe Mental Illness, Bipolar Disorder, Nonorganic Psychosis, Schizo-affective Disorder	50	Turkey (Türkiye)	clinicaltrials.gov
October 14, 2026	NCT07872878	BAROMETRE : Study on the Prognosis and Course of Individuals With Bipolar Spectrum Disorder	University Hospital, Angers	Observational	Not yet recruiting	Bipolar Disorder (BD)	60	France	clinicaltrials.gov
October 6, 2026	NCT07860957	Midday Bright Light Therapy for Bipolar Depression	Istanbul University - Cerrahpasa	Not applicable	Completed	Bipolar Disorder (BPD)	37	Turkey (Türkiye)	clinicaltrials.gov
October 5, 2026	NCT07858565	Quality of Life, Safety and Compliance of Patients Using Monotherapy or Combinatorial Therapy With Quetiapine for Treatment of...	Bosnalijek D.D	Observational	Recruiting	Schizophrenia, Bipolar Affective Disorder	500	Bosnia and Herzegovina	clinicaltrials.gov
September 28, 2026	NCT07845409	Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders	VA Office of Research and Development	Not applicable	Not yet recruiting	Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide, Suicidal Ideation, Mental Disorders	138	United States	clinicaltrials.gov
September 22, 2026	NCT07834112	Body Weight Changes After Switching to Lurasidone for Antipsychotic-induced Weight Gain in Bipolar Disorder	Dong-Wook Kim	Observational	Completed	Bipolar Disorder (BD)	155	South Korea	clinicaltrials.gov
September 22, 2026	NCT07833267	Cognition and Affective Research in China	Xuanwu Hospital, Beijing	Observational	Not yet recruiting	Neurodegenerative Disease, Dementia, Alzheimer's Disease, Parkinson's Disease, Mood Disorders, Depression, Anxiety...	3,000	China	clinicaltrials.gov
September 8, 2026	NCT07806227	Broadband Near Infrared Spectroscopy to Understand the Role of Brain Cytochrome C Oxidase in Bipolar Disorder	Martin Lan	Phase 4	Not yet recruiting	Bipolar Disorder Depression	60	United States	clinicaltrials.gov
August 25, 2026	NCT07783633	Identifying Biomarkers of Response to Digital Interventions for Mood Disorders	Centre for Addiction and Mental Health	Not applicable	Enrolling by invitation	Depression / Major Depressive Disorder, Bipolar Disorder (BD)	200	Canada	clinicaltrials.gov
August 18, 2026	NCT07771517	Role of Kynurenine Pathway and Its Metabolites in Depressive Disorders, Major Depressive Disorder is Suspected to Have the Greatest Burden...	Sohag University	Observational	Not yet recruiting	Major Depressive Disorder (MDD)	90		clinicaltrials.gov
August 17, 2026	NCT07767032	Project MOVE Bipolar	Butler Hospital	Not applicable	Completed	Bipolar Disorder (BD)	22	United States	clinicaltrials.gov
August 6, 2026	NCT07748910	Enhancing Resilience and Quality of Life in Bipolar Disorder Through Cognitive Behavioral Therapy	Cumhuriyet University	Not applicable	Completed	Bipolar Affective Disorder; Remission in	22	Turkey (Türkiye)	clinicaltrials.gov
August 4, 2026	NCT07745374	Safety and Feasibility of DBS for Bipolar Depression	Icahn School of Medicine at Mount Sinai	Not applicable	Recruiting	Bipolar I Disorder, Bipolar Depression	5	United States	clinicaltrials.gov
August 3, 2026	NCT07741981	Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment	Centre Hospitalier St Anne	Not applicable	Recruiting	Schizophrenia, Treatment Resistant Depression (TRD), Bipolar Disorder (BD), Catatonia, Obsessive Compulsive Disorder...	700	France	clinicaltrials.gov
July 31, 2026	NCT07740694	EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT	Istanbul University - Cerrahpasa	Observational	Recruiting	Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression...	62	Turkey (Türkiye)	clinicaltrials.gov
July 29, 2026	NCT07733297	The Effect of Cognitive Behavioral Psychoeducation on Internalized Stigma in Individuals With Bipolar Disorder	Eskisehir Osmangazi University	Not applicable	Completed	Bipolar Disorder (BD), Internalized Stigma, Psychoeducation	43	Turkey (Türkiye)	clinicaltrials.gov
July 29, 2026	NCT07732933	Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	Not applicable	Not yet recruiting	Bipolar Disorder (BD), Bipolar Disorder (BPD)	20	Italy	clinicaltrials.gov
July 13, 2026	NCT07699445	The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression	Massachusetts General Hospital	Phase 4	Recruiting	Bipolar Depression Depressed Phase, Obesity & Overweight	25	United States	clinicaltrials.gov
July 9, 2026	NCT07692984	The Effect of Comorbid Alcohol/Substance Use	Abant Izzet Baysal University	Observational	Recruiting	Alcohol Abuse, Alcohol Use Disorder, Substance Use Disorders, Severe Mental Disorder, Schizophrenia, Bipolar Disorder...	297	Turkey (Türkiye)	clinicaltrials.gov
July 6, 2026	NCT07684911	Longitudinal Study on the Sustainability of Transcranial Magnetic Stimulation Protocols - Biomarkers	Hospital Center Guillaume Régnier	Observational	Recruiting	Depression - Major Depressive Disorder, Depression Bipolar, Depression Unipolar	30	France	clinicaltrials.gov
July 2, 2026	NCT07680153	Neuromodulation of Mood Switch Circuitry in Bipolar Disorder	Weill Medical College of Cornell University	Phase 4	Recruiting	Bipolar Disorder (BD), Bipolar 1 Depression, rTMS, fMRI	62	United States	clinicaltrials.gov
July 1, 2026	NCT07679204	Type D Personality and Life Satisfaction in Bipolar Disorder Type 2 and Major Depressive Disorder	Elazığ Mental Health and Diseases Hospital	Observational	Recruiting	Bipolar Disorder II, Major Depressive Disorder (MDD)	180	Turkey (Türkiye)	clinicaltrials.gov
June 24, 2026	NCT07664852	Pramipexole vs Placebo Treatment in Bipolar Disorder With Anhedonic Depression	Daniel Lindqvist	Phase 3	Recruiting	Bipolar Disorder (BD)	126	Sweden	clinicaltrials.gov
June 17, 2026	NCT07654348	Efficacy and Mechanism of IPSRT for Bipolar II Disorder	First Affiliated Hospital of Zhejiang University	Phase 2	Not yet recruiting	Bipolar Disorder II	216	China	clinicaltrials.gov
June 11, 2026	NCT07643714	Effects of ACT-Based Psychoeducation on Caregivers of Individuals With Mental Disorders	Zeynep Özkök	Not applicable	Completed	Caregiver Burden, Mental Disorders	64	Turkey (Türkiye)	clinicaltrials.gov
June 8, 2026	NCT07632989	Virtual Reality-Based Cognitive Remediation in Schizophrenia and Bipolar Disorder	Università degli Studi di Brescia	Not applicable	Active not recruiting	Bipolar Disorder (BD), Schizophrenia Spectrum Disorders (SSD)	80	Italy	clinicaltrials.gov
June 3, 2026	NCT07622927	FOCUS Bipolar: Families Opening Conversations for Understanding Signs	University of Texas Southwestern Medical Center	Observational	Recruiting	Bipolar Disorder (BD), Bipolar Disorder I or II, Bipolar Disorder Family Members, Screening Tool	200	United States	clinicaltrials.gov
June 1, 2026	NCT07619092	Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy	Anders Jørgensen	Not applicable	Recruiting	Depression - Major Depressive Disorder, Bipolar Disorder (BD), Functional Magnetic Resonance Imaging (fMRI), Cognition...	145	Denmark	clinicaltrials.gov
May 18, 2026	NCT07592884	Rochester Forensic Assertive Community Treatment Model in Minnesota	University of Rochester	Not applicable	Completed	Schizophrenia, Bipolar Disorder, Criminal Behavior	40	United States	clinicaltrials.gov
May 15, 2026	NCT07589647	Research on the Efficacy and Safety of Targeted Suprachiasmatic Nucleus Electrical Stimulation for Improving Metabolic Disorders in...	First Affiliated Hospital of Zhejiang University	Not applicable	Recruiting	Bipolar Disorder (BD)	70	China	clinicaltrials.gov
May 14, 2026	NCT07586150	Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN)	Ludwig-Maximilians - University of Munich	Not applicable	Not yet recruiting	Severe Mental Illness, Depression / Major Depressive Disorder, Bipolar Disorder (BD), Schizophrenia	140	Austria, Germany, Netherlands	clinicaltrials.gov
May 7, 2026	NCT07573839	An Exploratory Study on the Prediction of Recurrence Risk of Bipolar Disorder Using Sentiment Analysis Technology Based on Multi-modal...	Shanghai Mental Health Center	Observational	Recruiting	Bipolar Disorder (BD), Healthy Control	400	China	clinicaltrials.gov
May 6, 2026	NCT07570875	Evaluating the Impact of Ketogenic Therapy on Symptom Severity and Metabolic Side Effect Profile Among Individuals Living With Bipolar...	University of Alabama at Birmingham	Not applicable	Not yet recruiting	Bipolar Disorder	100	United States	clinicaltrials.gov
May 6, 2026	NCT07569198	Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline...	Joshua Rosenblat	Phase 2	Recruiting	Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar...	120	Canada	clinicaltrials.gov
April 29, 2026	NCT07556861	Senyo Health App - Comorbid Alcohol Use Disorder Treatment in Individuals With Bipolar Disorder Using a Telehealth Collaborative Care...	Mayo Clinic	Not applicable	Not yet recruiting	Bipolar Disorder	40	United States	clinicaltrials.gov
April 29, 2026	NCT07556692	A Study of Home-use Brain Stimulation to Treat Bipolar Depression	King's College London	Not applicable	Recruiting	Bipolar Disorder (BD)	212	United Kingdom	clinicaltrials.gov
April 24, 2026	NCT07549581	A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 1	Completed	Schizophrenia, Major Depressive Disorder (MDD), Bipolar Disorder	43	United States	clinicaltrials.gov
April 23, 2026	NCT07548359	Psychiatric Nursing Intervention for Caregivers of Patients With Bipolar Disorder	Menoufia University	Not applicable	Completed	Bipolar Disorder, Caregiver Burden, Psychological Resilience	60	Egypt	clinicaltrials.gov
April 16, 2026	NCT07534475	Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT	Medipol University	Not applicable	Recruiting	Major Depressive Disorder, Bipolar Disorder, Schizophrenia	20	Turkey (Türkiye)	clinicaltrials.gov
April 3, 2026	NCT07510646	Transcranial Photobiomodulation for Bipolar Depression	Vielight Inc.	Not applicable	Not yet recruiting	Bipolar, Bipolar Disorder (BD), Bipolar Disorder Depression	40	Canada	clinicaltrials.gov
March 31, 2026	NCT07503275	Functional Magnetic Resonance Imaging Study of Inhibitory Control in Bipolar Disorder and Major Depressive Disorder	CHU de Reims	Not applicable	Not yet recruiting	Bipolar Disorder, Major Depressive Disorder	120	France	clinicaltrials.gov
March 18, 2026	NCT07479758	Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe...	Second Affiliated Hospital, Zhejiang University, School of Medicine	Observational	Recruiting	Major Depressive Disorder (MDD), Schizophrenia, Bipolar Disorder, Severe Mental Disorders	320	China	clinicaltrials.gov
March 16, 2026	NCT07472920	Empagliflozin Adjunctive Therapy in Bipolar Depression	University of Sao Paulo	Not applicable	Not yet recruiting	Bipolar Disorder, Bipolar Depression, Insulin Resistance	20	Brazil	clinicaltrials.gov
March 16, 2026	NCT07472075	Melatonin Versus Placebo for Bipolar Disorder	Lars Vedel Kessing	Phase 2	Recruiting	Bipolar Affective Disorder	200	Denmark	clinicaltrials.gov
March 11, 2026	NCT07463911	Treatment Response In ECT Patients	Nurdan Sağbaş	Observational	Active not recruiting	Major Depression, Bipolar Affective Disorder, Bipolar Depression Depressed Phase	65	Turkey (Türkiye)	clinicaltrials.gov
March 3, 2026	NCT07445802	Medication Adherence in Severe Mental Illness: a Promotion Program	Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz	Not applicable	Not yet recruiting	Treatment Adherence and Compliance, Severe Mental Disorders, Bipolar Disorder (BD), Schizophrenia Disorder	1,640		clinicaltrials.gov
March 3, 2026	NCT07444463	Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications	Central South University	Not applicable	Not yet recruiting	Schizophrenia, Bipolar Disorder, Major Depressive Disorder (MDD)	400	China	clinicaltrials.gov
February 27, 2026	NCT07437833	Psychophysiological Responses to Six Single-Session Self-Regulation Interventions in a Female Adult With ADHD and Stabilized Bipolar...	Poznan University of Physical Education	Not applicable	Recruiting	ADHD - Attention Deficit Disorder With Hyperactivity, Bipolar Affective Disorder; Remission in	1	Poland	clinicaltrials.gov
February 25, 2026	NCT07434414	LRFN5 and OLFM4 in Bipolar Disorder	Elazığ Mental Health and Diseases Hospital	Observational	Completed	Bipolar Disorder (BD)	72	Turkey (Türkiye)	clinicaltrials.gov
February 23, 2026	NCT07427966	Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder	Karolinska Institutet	Observational	Not yet recruiting	Major Depressive Disorder, Mood Disorders, Bipolar Disorder (BD)	600		clinicaltrials.gov
February 17, 2026	NCT07414147	TMS for Improving Cognitive Function in Bipolar Disorder	First Affiliated Hospital of Zhejiang University	Not applicable	Not yet recruiting	Bipolar Disorder (BD), Cognitive Impairment	88	China	clinicaltrials.gov
February 17, 2026	NCT07412132	Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II.	University of Sao Paulo	Phase 3	Recruiting	Bipolar Affective Disorder	40	Brazil	clinicaltrials.gov
February 13, 2026	NCT07411222	Emotional Eating, Sleep Quality, Mental State and Metabolic Syndrome	Abant Izzet Baysal University	Observational	Recruiting	Schizophrenia, Bipolar Disorder, Psychiatric Issue, Metabolic Syndrome, Emotional Eating, Sleep, Mediating	78	Turkey (Türkiye)	clinicaltrials.gov
February 12, 2026	NCT07404943	The Effect of Telenursing on Functionality and Treatment Adherence in Bipolar Disorder	Didem Ayhan	Not applicable	Completed	Bi-Polar Disorder	70	Turkey (Türkiye)	clinicaltrials.gov
February 11, 2026	NCT07404085	Epigenetic Enhancement of Cognitive Training in Aging Mood and Schizophrenia Spectrum Disorder Populations	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	Not applicable	Recruiting	Bipolar Disorder (BD), Depression - Major Depressive Disorder, Cognitive Impairment, Schizophrenia Disorders	160	Denmark	clinicaltrials.gov
February 10, 2026	NCT07399626	Adaptation and Validation of the Hypomanic Personality Scale (HPS-6) to Romanian	Babes-Bolyai University	Phase 1/2	Recruiting	Bipolar Disorder (BD)	50	Romania	clinicaltrials.gov
February 9, 2026	NCT07398365	Medical Phenotyping of NHS General Adult Psychiatry (GAP) Inpatients	University of Edinburgh	Observational	Recruiting	Bipolar Affective Disorder, Schizophrenia Disorders, Depression Disorders, Personality Disorders	100	United Kingdom	clinicaltrials.gov
February 9, 2026	NCT07396363	Psychoeducational Psychotherapy in Adolescent Bipolar Disorder	Dokuz Eylul University	Not applicable	Completed	Bipolar Disorder (BD)	32	Turkey (Türkiye)	clinicaltrials.gov
February 5, 2026	NCT07389473	Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device	Gaize	Observational	Recruiting	ADHD, Depression Disorders, Mood Disorders, Anxiety Disorder Generalized, Bipolar Disorder (BPD)	50	United States	clinicaltrials.gov
January 15, 2026	NCT07343739	Bipolar Disorder Integrative Staging: Incorporating Biomarkers Into Progression Across Stages	ASST Fatebenefratelli Sacco	Observational	Active not recruiting	Bipolar Disorder	126	Italy	clinicaltrials.gov
January 13, 2026	NCT07337889	Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder	University Hospital, Montpellier	Not applicable	Recruiting	Borderline Personality Disorder, Borderline Personality Disorder (BPD), Bipolar Disorder (BD)	194	France	clinicaltrials.gov
January 9, 2026	NCT07329673	An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms	Qbtech AB	Observational	Suspended	Bi-Polar Disorder, Autism Spectrum Disorder (ASD), Major Depression Disorders, Separation Anxiety Disorder, Social...	300	United States	clinicaltrials.gov
January 5, 2026	NCT07316803	Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness	Centre hospitalier de Ville-Evrard, France	Not applicable	Recruiting	Severe Mental Illness, Schizophrenia, Bipolar Disorder, Major Depressive Disorder	20	France	clinicaltrials.gov
December 29, 2025	NCT07306468	Effects of Schizophrenia and Bipolar Disorder on Exercise Capacity, Pulmonary Function, and Quality of Life	Çankırı Karatekin University	Observational	Recruiting	Schizophenia Disorder, Bipolar Disorder (BD)	150	Turkey (Türkiye)	clinicaltrials.gov
December 29, 2025	NCT07306039	Feasibility of eLi12	Ole Köhler-Forsberg	Not applicable	Active not recruiting	Bipolar Disorder (BD)	200	Denmark	clinicaltrials.gov
December 23, 2025	NCT07298278	Anticipating Depressive and Manic Episodes in Bipolar Disorders Using Vocal Biomarkers	Centre Hospitalier St Anne	Not applicable	Not yet recruiting	Bipolar Disorder (BD)	170		clinicaltrials.gov
December 22, 2025	NCT07297056	Mindfulness Psychoeducation for Bipolar Disorder	Ömer USLU	Not applicable	Completed	Bipolar Disorder (BD), Mindfulness-Based Stress Reduction, Mindfulness Meditation	40	Turkey (Türkiye)	clinicaltrials.gov
December 19, 2025	NCT07295652	Characterization of High-Level Cognitive Impairments in Patients With Neuropsychiatric Disorders	Centre Hospitalier St Anne	Not applicable	Recruiting	Neurologic Disorders, Schizophrenia, Bipolar Disorder (BD), Depressive Disorder	600	France	clinicaltrials.gov
December 16, 2025	NCT07286175	A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)	Eli Lilly and Company	Phase 2	Recruiting	Bipolar Disorder	400	Argentina, Brazil, China, India, Japan, Mexico, Puerto Rico, United States	clinicaltrials.gov
December 5, 2025	NCT07266545	RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)	Mayo Clinic	Phase 4	Recruiting	Unipolar Depression, Bipolar Depression	120	United States	clinicaltrials.gov
December 4, 2025	NCT07263191	A Study of Olanzapine in Participants With Bipolar Disorder.	Boryung Pharmaceutical Co., Ltd	Observational	Recruiting	Bipolar Disorder	3,000	South Korea	clinicaltrials.gov
November 25, 2025	NCT07247344	Multimodal Phenotyping in Adolescent Inpatient Depression: An Observational Study	Jiangsu Province Nanjing Brain Hospital	Observational	Recruiting	Adolescent, Major Depressive Disorder (MDD, Bipolar Disorder (BD)	1,000	China	clinicaltrials.gov
November 24, 2025	NCT07246044	HD-tDCS for Adolescent Bipolar Depression Targeting S1	Jiangsu Province Nanjing Brain Hospital	Not applicable	Recruiting	Adolescent, Bipolar Depression, tDCS, Primary Somatosensory Cortex, Bipolar Disorder Depression	100	China	clinicaltrials.gov
November 20, 2025	NCT07239778	The PEDAL Intervention - Reducing Affective Lability in Bipolar Disorder	Oslo University Hospital	Phase 2	Recruiting	Bipolar Disorder (BD)	120	Norway	clinicaltrials.gov
November 19, 2025	NCT07234851	Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs.	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	Observational	Enrolling by invitation	Schizophrenia Disorder, Frontotemporal Dementia, Behavioral Variant, Major Depressive Disorder (MDD), Bipolar Disorder...	150	Spain	clinicaltrials.gov
October 28, 2025	NCT07221864	Decoding Emotional Dynamics in Bipolar Disorder	Laureate Institute for Brain Research, Inc.	Not applicable	Recruiting	Bipolar Disorder I or II, Healthy (Controls)	72	United States	clinicaltrials.gov
October 20, 2025	NCT07217860	An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE)	Xenon Pharmaceuticals Inc.	Phase 3	Active not recruiting	Bipolar Depression, Bipolar I Disorder, Bipolar Disorder, Bipolar II Disorder	400	United States	clinicaltrials.gov
October 9, 2025	NCT07213492	Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder	McMaster University	Not applicable	Recruiting	Bipolar Disorder (BD), Psychosis	10	Canada	clinicaltrials.gov
October 9, 2025	NCT07213466	Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder	Mayo Clinic	Phase 4	Recruiting	Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity, Weight Loss, GLP - 1	100	United States	clinicaltrials.gov
October 8, 2025	NCT07212075	Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups	Forschungsinstitut der Diabetes Akademie Mergentheim	Observational	Recruiting	Diabetes (DM), Diabete Mellitus, Diabete Type 1, Diabete Type 2, Diabetes Distress, Diabetes Complications, Depression...	1,809	Germany	clinicaltrials.gov
October 8, 2025	NCT07211750	Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT	KU Leuven	Not applicable	Recruiting	Multimorbidity, Older Adults (65 Years and Older), Mood Disorders, Depression - Major Depressive Disorder, Bipolar...	82	Belgium	clinicaltrials.gov
October 7, 2025	NCT07211217	Time Restricted Eating (TRE) in Bipolar Disorder	Massachusetts General Hospital	Not applicable	Recruiting	Bipolar Disorder (BD), Bipolar Disorder Depression, Overweight (BMI > 30)	40	United States	clinicaltrials.gov
September 24, 2025	NCT07189689	Mental Health Mission Mood Disorder Cohort Study	University of Oxford	Observational	Not yet recruiting	Depression - Major Depressive Disorder, Depression Bipolar, Treatment Resistant Depression	2,000	United Kingdom	clinicaltrials.gov
September 15, 2025	NCT07173842	NeuroPsyBiT-BD Omics: Genomic & Epigenomic Biobank of Bipolar Disorder	Selçuk State Hospital	Observational	Not yet recruiting	Bipolar Disorder	1,000	Turkey (Türkiye)	clinicaltrials.gov
September 15, 2025	NCT07172516	A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)	Xenon Pharmaceuticals Inc.	Phase 3	Active not recruiting	Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder	400	Bulgaria, Germany, Spain, United States	clinicaltrials.gov
September 11, 2025	NCT07167563	Real-world Lithium Intake	University of Aarhus	Observational	Recruiting	Bipolar Disorder (BD)	50	Denmark	clinicaltrials.gov
September 3, 2025	NCT07151846	Digital Phenotypes for Predicting Depression	Korea University Anam Hospital	Observational	Enrolling by invitation	Depression - Major Depressive Disorder, Depression Bipolar, Bipolar Disorder (BD), Mood Disorders	540	South Korea	clinicaltrials.gov
August 26, 2025	NCT07140913	A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants...	Bristol-Myers Squibb	Phase 3	Recruiting	Mania, Bipolar Disorder	424	Argentina, Bulgaria, China, Denmark, France, India, Israel, Italy, Japan...	clinicaltrials.gov
August 24, 2025	NCT07140042	Physical Fitness, Physical Activity Level, Depression and Quality of Life in Bipolar and Schizophrenia Patients	Dr. Lutfi Kirdar Kartal Training and Research Hospital	Observational	Completed	Bipolar Disorder (BD), Schizophrenia Disorder	62	Turkey (Türkiye)	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
First Affiliated Hospital of Zhejiang University	5	June 17, 2026
Mayo Clinic	5	April 29, 2026
Centre Hospitalier St Anne	4	August 3, 2026
Korea University Anam Hospital	3	October 29, 2026
VA Office of Research and Development	3	September 28, 2026
Shanghai Mental Health Center	3	May 7, 2026
Peking University	3	June 5, 2025
Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	2	November 5, 2026
Assiut University	2	November 2, 2026
Second Affiliated Hospital, Zhejiang University, School of Medicine	2	October 29, 2026
University of British Columbia	2	October 22, 2026
Istanbul University - Cerrahpasa	2	October 6, 2026
Butler Hospital	2	August 17, 2026
Massachusetts General Hospital	2	July 13, 2026
Abant Izzet Baysal University	2	July 9, 2026
Hospital Center Guillaume Régnier	2	July 6, 2026
Elazığ Mental Health and Diseases Hospital	2	July 1, 2026
University of Rochester	2	May 18, 2026
King's College London	2	April 29, 2026
CHU de Reims	2	March 31, 2026

By phase

Phase	New trials	Latest
Not applicable	81	November 5, 2026
Observational	53	November 6, 2026
Phase 2	11	November 3, 2026
Phase 4	8	September 8, 2026
Phase 3	6	June 24, 2026
Phase 1	4	November 6, 2026
Phase 1/2	1	February 10, 2026
Early phase 1	1	December 13, 2024

By country

Country	New trials	Latest
United States	45	November 3, 2026
Turkey (Türkiye)	22	October 16, 2026
China	19	October 29, 2026
France	16	October 19, 2026
Canada	11	October 22, 2026
Denmark	9	November 5, 2026
Italy	5	July 29, 2026
United Kingdom	5	April 29, 2026
Spain	4	November 6, 2026
South Korea	4	October 19, 2026
Germany	4	May 14, 2026
Brazil	3	March 16, 2026
Sweden	2	June 24, 2026
Austria	2	May 14, 2026
Poland	2	February 27, 2026
Romania	2	February 10, 2026
Argentina	2	December 16, 2025
India	2	December 16, 2025
Japan	2	December 16, 2025
Norway	2	November 20, 2025
Bulgaria	2	September 15, 2025
Israel	2	August 26, 2025
Bahrain	1	October 16, 2026
Bosnia and Herzegovina	1	October 5, 2026
Netherlands	1	May 14, 2026

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.