Data / New clinical trials / Aortic Valve Stenosis

Aortic Valve Stenosis trials: 152 new since Nov 2024

Name: New Aortic Valve Stenosis clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Aortic Valve Stenosis clinical trials: 152 rows for $7.60, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 4 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/aortic-valve-stenosis, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 9, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

152 clinical studies in Aortic Valve Stenosis were first posted on ClinicalTrials.gov from November 15, 2024 to November 9, 2026; 31 have an industry sponsor and 120 are recruiting or about to. The newest, NCT07926022, was posted on November 9, 2026: TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patients With Severe Aortic Stenosis (Alexandria University).

The request: Every new Aortic Valve Stenosis clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

152New trials
31Industry sponsored
120Recruiting or not yet
November 9, 2026Latest posted

Newest trials

The newest 100 of 152, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 9, 2026	NCT07926022	TAVI and PCI in Comparison to SAVR and CABG in Low and Intermediate Risk Patients With Severe Aortic Stenosis	Alexandria University	Observational	Recruiting	Aortic Stenosis Disease, Coronary Artery Disease (CAD)	100	Egypt	clinicaltrials.gov
November 3, 2026	NCT07912905	Effect of Double-Tap Optimization on Valve Expansion and Hemodynamics in Balloon-expandable Transcatheter Aortic Valve Implantation: A...	Yonsei University	Not applicable	Not yet recruiting	Severe Aortic Stenosis	250		clinicaltrials.gov
November 2, 2026	NCT07908355	Society of Thoracic Surgeons and American College of Cardiology Transcatheter Valve Therapy Registry (STS/ACC TVT Registry™): Registry...	American College of Cardiology	Observational	Recruiting	Aortic Valve Stenosis	50,000	United States	clinicaltrials.gov
November 2, 2026	NCT07908225	Target Value Study to Evaluate the Safety and Efficacy of the Taurus NXT® Transcatheter Aortic Valve System for the Treatment of Severe...	Peijia Medical Technology (Suzhou) Co., Ltd.	Not applicable	Active not recruiting	Aortic Stenosis	150	China	clinicaltrials.gov
October 26, 2026	NCT07895719	Exercise and Diet Supplements for Older Patients Undergoing TAVI: the IRON-TAVI Trial	University Hospital of Ferrara	Not applicable	Recruiting	Aortic Stenosis Disease, Aortic Stenosis Symptomatic, Aortic Stenosis	450	Italy	clinicaltrials.gov
October 13, 2026	NCT07872020	SYMmetric Valve fraME Expansion To Reduce hYpoattenuated Leaflet Thickening After Balloon-expandable TAVI: the SYMMETRY Trial	Erasmus Medical Center	Not applicable	Recruiting	Aortic Valve Stenosis and/or Insufficiency, Hypoattenuated Leaflet Thickening, Valve Expansion, Transcatheter Aortic...	422	Germany, Netherlands	clinicaltrials.gov
September 18, 2026	NCT07828730	Sparrow App Guided Evaluation (SAGE) Vanguard Trial for Aortic Stenosis in Adults Aged Seventy and Older	Sunnybrook Health Sciences Centre	Not applicable	Not yet recruiting	Moderate or Severe Aortic Stenosis	1,000		clinicaltrials.gov
September 18, 2026	NCT07827105	ECG-based AI Screening for Cases of Undiagnosed Moderate-to-Severe Aortic Stenosis in the Primary Care Setting	AccurKardia, Inc.	Observational	Enrolling by invitation	Aortic Stenosis	4,000	United States	clinicaltrials.gov
September 14, 2026	NCT07819344	Molecular Imaging to Identify Predictors of Aortic Valve Disease Activity	Massachusetts General Hospital	Observational	Not yet recruiting	AORTIC VALVE DISEASES, Calcification; Heart	100		clinicaltrials.gov
September 10, 2026	NCT07813273	Coronary Access After Evolut FX Plus TAVI: Impact of Commissural Alignment and the Large-Cell Frame Design: ACCESS-FX+ Registry	Yonsei University	Observational	Not yet recruiting	Severe Aortic Stenosis	122		clinicaltrials.gov
September 8, 2026	NCT07806409	Safety and Clinical Performance of the Next-Generation SAFESYNC Transcatheter Heart Valve in Patients With Severe Aortic Stenosis	Braile Biomedica Ind. Com. e Repr. Ltda.	Not applicable	Not yet recruiting	Aortic Stenosis Senile, Aortic Stenosis Symptomatic, Aortic Stenosis	40		clinicaltrials.gov
September 1, 2026	NCT07798713	Quality of Life After Transcatheter Aortic Valve Implantation	Aalborg University Hospital	Observational	Active not recruiting	Aortic Stenosis, Heart Failure, Angina Pectoris, TAVI(Transcatheter Aortic Valve Implantation)	200	Denmark	clinicaltrials.gov
August 31, 2026	NCT07794436	Association Between Changes in Aortic Valve Area and Pulmonary Congestion After Transcatheter Aortic Valve Implantation	Istanbul University - Cerrahpasa	Observational	Recruiting	Aortic Stenosis	52	Turkey (Türkiye)	clinicaltrials.gov
August 31, 2026	NCT07794306	Balloon- Versus Self-Expanding Intraannular TAVI in Small Aortic Annuli	Universitätsklinikum Hamburg-Eppendorf	Not applicable	Not yet recruiting	Aortic Valve Stenosis	510	Germany	clinicaltrials.gov
August 10, 2026	NCT07756398	Importance of Point-of-Care Ultrasound for Early Detection of Valvular and Cardiac Diseases (IMPROVE)	University of Texas Southwestern Medical Center	Not applicable	Not yet recruiting	Valvular Heart Disease Patients, Aortic Stenosis, Mitral Regurgitation, Left Ventricular Diastolic Dysfunction	1,088	United States	clinicaltrials.gov
August 7, 2026	NCT07752732	Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Grade Aortic Valve Stenosis - Evaluation Using...	University Hospital Tuebingen	Observational	Recruiting	Amyloidosis Cardiac, Stenosis Coronary, TAVI(Transcatheter Aortic Valve Implantation)	600	Germany	clinicaltrials.gov
August 4, 2026	NCT07743697	Comparing Suture vs. Combined Closure Strategies for Large Blood Vessel Access in Patients Undergoing Transcatheter Aortic Valve...	University Hospital, Basel, Switzerland	Not applicable	Not yet recruiting	Aortic Valve Stenosis, Postoperative Complications, Vascular System Injuries, Hemorrhage	705	Switzerland	clinicaltrials.gov
July 31, 2026	NCT07739316	Systematic Ambulatory ECG Monitoring Following TAVI	Institut universitaire de cardiologie et de pneumologie de Québec, University Laval	Not applicable	Recruiting	Aortic Stenosis, Conduction Disturbances	754	Canada	clinicaltrials.gov
July 31, 2026	NCT07738575	Same-Day Versus Standard Hospital Discharge After TAVI (HOME-TAVI)	Hospital Clinic of Barcelona	Not applicable	Not yet recruiting	Aortic Stenosis, Severe, Aortic Stenosis	764	Canada, Spain	clinicaltrials.gov
July 29, 2026	NCT07735130	Angiotensin Receptor Blocker After TAVR in Severe Aortic Stenosis With Left Ventricular Hypertrophy (ARBITAR)	Seoul National University Hospital	Phase 4	Not yet recruiting	Transcatheter Aortic Valve Replacement (TAVR), Left Ventricular Hypertrophy, Severe Aortic Stenosis	632	South Korea	clinicaltrials.gov
July 29, 2026	NCT07734025	A Prospective, Multi-centre, Single Arm, Pivotal Clinical Study to Determine the Safety and Effectiveness of Crea Aortic Valve for Use as a...	Onecrea Medical Inc.	Not applicable	Not yet recruiting	Aortic Valve Stenosis, Severe Aortic Stenosis	30		clinicaltrials.gov
July 20, 2026	NCT07715279	Vericiguat for the Inhibition of Calcific Aortic Valve Stenosis Progression	West China Hospital	Phase 2	Recruiting	Calcific Aortic Valve Disease, AORTIC VALVE DISEASES, Aortic Valve Stenosis	238	China	clinicaltrials.gov
July 17, 2026	NCT07709858	CHATEAU Registry: Clinical Outcomes After Transcatheter Aortic Valve Replacement	Eunpyeong St. Mary's Hospital	Observational	Recruiting	Aortic Valve Stenosis, Transcatheter Aortic Valve Replacement (TAVR)	4,000	South Korea	clinicaltrials.gov
July 8, 2026	NCT07690748	Remote Monitoring for Patients With Aortic Stenosis	Baker Heart and Diabetes Institute	Observational	Not yet recruiting	Aortic Stenosis	160		clinicaltrials.gov
July 8, 2026	NCT07689279	Selection of Transcatheter Heart vaLve With Intermediate Sizing in Patients With Severe Aortic Stenosis Treated With Transcatheter Aortic...	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Phase 4	Not yet recruiting	Aortic Stenosis, Severe	604		clinicaltrials.gov
June 4, 2026	NCT07626710	Impact of Trans-catheter Aortic Valve Implantation on Renal Function	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	Observational	Recruiting	Aortic Valve Stenosis, Chronic Kidney Diseases, Renal Failure Acute Chronic	1,000	Italy	clinicaltrials.gov
June 4, 2026	NCT07626567	Prospective Neuropsychological Evaluation of the Implementation of a Heart Valve Unit (HVU-NEURO)	Heart and Brain Research Group, Germany	Observational	Not yet recruiting	Aortic Valve Stenosis, Postoperative Cognitive Dysfunction (POCD), Delirium - Postoperative, Neurocognitive Disorders	500		clinicaltrials.gov
June 3, 2026	NCT07623083	Evaluation of a Management Algorithm for TAVI Patients With Concomitant Mitral or Tricuspid Regurgitation	Josep Rodes-Cabau	Observational	Not yet recruiting	Aortic Stenosis, Mitral Regurgitation, Tricuspid Regurgitation, Transcatheter Aortic Valve Implantation (TAVI)	300		clinicaltrials.gov
June 2, 2026	NCT07620925	Derivation and Validation of the Aortic Valve Echocardiographic Calcium Score to Confirm Severe Aortic Stenosis: the Echo-AVCS Study	Azienda Ospedaliera "Sant'Andrea"	Observational	Recruiting	Aortic Stenosis, Chronic Coronary Syndrome, Calcific Aortic Valve Disease, Calcific Aortic Stenosis	250	Italy	clinicaltrials.gov
May 29, 2026	NCT07614100	Cerebral Microembolization During Transcatheter Aortic Valve Implantation: Comparing Balloon-expandable and Self-expanding Valves	Ivan Zeljkovic	Not applicable	Not yet recruiting	Aortic Stenosis	80	Croatia	clinicaltrials.gov
May 26, 2026	NCT07605780	TAVI in LOW RISK in the REAL WORLD	Centro Cardiologico Monzino	Observational	Completed	Aortic Valve Stenosis	650	Italy	clinicaltrials.gov
May 26, 2026	NCT07605624	Active Post-Market Surveillance of Innovative Devices for Valvular Heart Disease	Beijing Anzhen Hospital	Observational	Not yet recruiting	Aortic Stenosis, Aortic Regurgitation, Mitral Regurgitation, Tricuspid Regurgitation	5,500	China	clinicaltrials.gov
May 22, 2026	NCT07604402	TRanscatheter Aortic-Valve Implantation Without On-site Cardiac Surgery	University Hospital of Ferrara	Not applicable	Recruiting	Aortic Stenosis	1,612	Italy	clinicaltrials.gov
May 19, 2026	NCT07596394	A Registry to Assess the Efficacy and Safety of Transcatheter Treatment for Aortic Valve Disease at the IRCCS Policlinico San Matteo...	Fondazione IRCCS Policlinico San Matteo di Pavia	Observational	Recruiting	Severe Aortic Stenosis	500	Italy	clinicaltrials.gov
May 5, 2026	NCT07566624	Spanish Prospective Registry of Hydra THV for Transcatheter Aortic Valve Implantation	Fundación EPIC	Observational	Recruiting	Severe Aortic Valve Stenosis, Valvular Heart Disease, Aortic Valve Stenosis	100	Spain	clinicaltrials.gov
April 29, 2026	NCT07556523	Patient Quality of Recovery After TAVR With Different Sedation Regimens	David Lyubashevsky	Phase 4	Recruiting	Transcatheter Aortic Valve Replacement (TAVR), Aortic Valve Stenosis	126	United States	clinicaltrials.gov
April 22, 2026	NCT07545369	ULTRA-EVOLUT RCT: A Comparison of Latest-Generation TAVR Valves	Assiut University	Not applicable	Not yet recruiting	Severe Aortic Valve Stenosis	200	Egypt	clinicaltrials.gov
April 20, 2026	NCT07539909	Alternative Peripheral TAVI Accesses	Medical University of Silesia	Observational	Not yet recruiting	Aortic Stenosis	600		clinicaltrials.gov
April 20, 2026	NCT07539259	Regression in Left Ventricular Hypertrophy and Fibrosis in Aortic Stenosis	University College, London	Phase 2	Not yet recruiting	Aortic Stenosis	445		clinicaltrials.gov
April 9, 2026	NCT07520656	Impact of Transcatheter Aortic Valve Implantation and Mitral Valve Repair on Sleep-Disordered Breathing	Aristides Plaitis	Observational	Recruiting	Sleep-disordered Breathing (SDB), Aortic Valve Stenosis, Mitral Valve Regurgitation	150	Greece	clinicaltrials.gov
April 9, 2026	NCT07520591	Valvosoft Outcomes Registry for Real-World Evidence	Cardiawave SA	Observational	Not yet recruiting	Aortic Valve Disease, Aortic Stenosis, Severe, Aortic Valve Calcification, Ultrasound Therapy, Heart Failure	200	France, Germany, Netherlands	clinicaltrials.gov
April 7, 2026	NCT07515768	TAVI Without On-Site Cardiac Surgery in Poland: A Randomized Multicenter Trial Protocol	Medical University of Warsaw	Not applicable	Not yet recruiting	Aortic Stenosis	404		clinicaltrials.gov
April 3, 2026	NCT07509554	PRessure-based Evaluation of Disease Improvement in the Course of TAVI	Istanbul Mehmet Akif Ersoy Educational and Training Hospital	Observational	Not yet recruiting	Aortic Stenosis	100	Turkey (Türkiye)	clinicaltrials.gov
March 18, 2026	NCT07479992	Multicenter Study for the Validation of Willem AI: Aortic StenoSis Early Diagnosis With AI-electrocardiogram Study	Idoven 1903 S.L.	Observational	Recruiting	Aortic Stenosis	5,000	Germany	clinicaltrials.gov
March 17, 2026	NCT07477002	Post-Dilatation in Balloon-Expandable TAVI Prostheses	Medical University of Vienna	Not applicable	Active not recruiting	Aortic Valve Stenosis	146	Austria	clinicaltrials.gov
March 13, 2026	NCT07469371	CLEAR-AS: CT-FFR-Guided Revascularization in Patients With Severe Aortic Stenosis	Yan'an Affiliated Hospital of Kunming Medical University	Not applicable	Recruiting	Severe Aortic Stenosis	300	China	clinicaltrials.gov
March 6, 2026	NCT07456280	Pilot Study to Evaluate a Noninvasive Electrocardiographic Monitoring Strategy Associated With Early Discharge in Patients With Conduction...	Hospital Universitari Vall d'Hebron Research Institute	Not applicable	Recruiting	Severe Aortic Valve Stenosis, Cardiovascular Diseases	100	Spain	clinicaltrials.gov
March 6, 2026	NCT07455292	Phenotyping Left Ventricle Failure With Hemodynamic Biomarkers From 4D Flow Magnetic Resonance Imaging	IRCCS Policlinico S. Donato	Not applicable	Recruiting	Left Ventricle Function, Transcatheter Aortic Valve Replacement (TAVR), Aortic Valve Stenosis	190	Italy	clinicaltrials.gov
March 4, 2026	NCT07450196	A Prospective, Multicenter, Observational Study Evaluating Safety and Effectiveness of SAPIEN 3 Transcatheter Aortic Valve Replacement for...	Chinese Academy of Medical Sciences, Fuwai Hospital	Observational	Not yet recruiting	Aortic Stenosis, AORTIC VALVE DISEASES	170	China	clinicaltrials.gov
March 2, 2026	NCT07442357	The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial	Copenhagen University Hospital, Rigshospitalet	Not applicable	Recruiting	Aortic Valve Stenosis	1,986	Denmark, Sweden	clinicaltrials.gov
February 24, 2026	NCT07430267	Dilation Optimisation for Uniform Bioprosthetic Leaflet Expansion	The Alfred	Not applicable	Not yet recruiting	Aortic Stenosis, TAVI(Transcatheter Aortic Valve Implantation)	250	Australia	clinicaltrials.gov
February 19, 2026	NCT07420907	Study of the Progression of Chronic Cardiovascular Conditions	Prolaio	Observational	Recruiting	Cardiovascular Disease (CVD), Heart Failure, Aortic Stenosis, Aortic Stenosis Disease, Hypertension, Hypertension...	5,000	United States	clinicaltrials.gov
February 17, 2026	NCT07414342	Safety and Efficacy of the RENATUS® Transcatheter Aortic Valve System for the Treatment of Severe Aortic Stenosis	Beijing Balance Medical Technology Co., Ltd	Not applicable	Recruiting	Severe Aortic Stenosis	800	China	clinicaltrials.gov
February 5, 2026	NCT07390513	Electrophysiological Outcomes After Transcatheter Aortic Valve Replacement	Chinese Academy of Medical Sciences, Fuwai Hospital	Observational	Active not recruiting	Aortic Valve Stenosis, Arrhythmia	1,000	China	clinicaltrials.gov
January 27, 2026	NCT07370688	Iron Infusion in Patients Undergoing Transcatheter Aortic Valve Implantation	Erasmus Medical Center	Phase 4	Recruiting	Aortic Valve Stenosis, Iron Deficiency, TAVI(Transcatheter Aortic Valve Implantation), Cardiovascular Diseases	402	Netherlands	clinicaltrials.gov
January 22, 2026	NCT07359898	International Multicenter Study of the Navitor/Navitor Vision Transcatheter Aortic Valve Platform	IRCCS Policlinico S. Donato	Observational	Recruiting	Severe Native Aortic Stenosis	1,000	Italy	clinicaltrials.gov
January 15, 2026	NCT07343674	PERFECT - Portuguese Evolut Registry Studying the Outcomes of Medtronic Evolut™ FX+ TAVI System by Evaluating an Optimal Care Pathway for...	Portuguese Association of Interventional Cardiology	Observational	Recruiting	Severe Symptomatic Aortic Stenosis (Defined as New York Heart Association (NYHA) Class ≥ II)	500	Portugal	clinicaltrials.gov
January 13, 2026	NCT07335900	A Clinical Study Using FAPI-PET Imaging to Assess the Postoperative Effects of TAVI in Patients With Aortic Stenosis	RenJi Hospital	Not applicable	Recruiting	Severe Aortic Valve Stenosis	25	China	clinicaltrials.gov
January 9, 2026	NCT07331116	Echocardiography Findings in Patients With Myocardial Fibrosis and Severe Aortic Stenosis	Norwegian University of Science and Technology	Observational	Completed	Aortic Valve Stenosis, Myocardial Fibrosis	22	Norway	clinicaltrials.gov
January 5, 2026	NCT07317804	Echo-Guided vs Fluoroscopy-Guided Transcatheter Aortic Valve Replacement in Patients With Aortic Stenosis（ECHO-TAVR）	China National Center for Cardiovascular Diseases	Phase 4	Not yet recruiting	Aortic Stenosis, TAVI, TAVI(Transcatheter Aortic Valve Implantation)	212	China	clinicaltrials.gov
December 30, 2025	NCT07309029	Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR	Atlantic Health System	Observational	Recruiting	Severe Aortic Stenosis, Cardiogenic Shock, Cardiogenic Shock, ECMO, Trans-catheter Aortic Valve Implantation	30	United States	clinicaltrials.gov
December 26, 2025	NCT07304427	Alwide Plus China Post-market Clinical Investigation	Shanghai MicroPort CardioFlow Medtech Co., Ltd.	Observational	Completed	Severe Aortic Stenosis, Transcatheter Aortic Valve Replacemen	75	China	clinicaltrials.gov
December 16, 2025	NCT07284550	Smartphone Based Digital Screening for Aortic Valve Stenosis	Medical University Innsbruck	Observational	Recruiting	Aortic Valve Stenosis, Artifical Intelligence	500	Austria	clinicaltrials.gov
December 12, 2025	NCT07278310	STAR Trial (Siegel Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis)	MiRus	Not applicable	Recruiting	Symptomatic Severe Native Aortic Stenosis, Aortic Stenosis	1,025	United States	clinicaltrials.gov
December 11, 2025	NCT07276711	CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material	EmStop Inc	Not applicable	Recruiting	Aortic Valve Stenosis, Aortic Stenosis, Aortic Valve Disease	663	United States	clinicaltrials.gov
December 5, 2025	NCT07267117	Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease	Second Affiliated Hospital, Zhejiang University, School of Medicine	Observational	Recruiting	Heart Valve Disease, Mitral Valve (MV) Regurgitation, Mitral Valve Disease, Mitral Valve Stenosis, Aortic Valve...	10,000	China	clinicaltrials.gov
December 2, 2025	NCT07258706	Demographic and Interpopulation Variations in Evaluation and Results of TAVI	Poznan University of Medical Sciences	Observational	Enrolling by invitation	Aortic Stenosis, TAVI(Transcatheter Aortic Valve Implantation), Computed Tomography, Inflammatory Response During...	800	Italy, Poland, Serbia, Thailand, Turkey (Türkiye)	clinicaltrials.gov
November 26, 2025	NCT07251660	Comparison of Early Postoperative Outcomes Between Minimally Invasive Valve Surgery Via Right Thoracotomy and Conventional Valve Surgery...	Chaudhry Pervaiz Elahi Institute of Cardiology	Not applicable	Not yet recruiting	Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis, Aortic Valve Insufficiency, Valvular Heart Disease Stenosis...	32		clinicaltrials.gov
November 20, 2025	NCT07240025	Anatomical Determinants and Outcomes of Small Annulus Patients Undergoing TAVR in Different ASIAN Ethnicity	Prince of Wales Hospital, Shatin, Hong Kong	Observational	Enrolling by invitation	Aortic Stenosis	31	Hong Kong	clinicaltrials.gov
November 17, 2025	NCT07230964	Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacement Fibrosis	Dermed Diagnostics, Inc.	Not applicable	Recruiting	Aortic Stenosis	6	United States	clinicaltrials.gov
October 16, 2025	NCT07217691	Optimization of Commissural Alignment During Transcatheter Aortic Valve Implantation With Evolut FX+	Oslo University Hospital	Not applicable	Not yet recruiting	Aortic Stenosis, Trans-catheter Aortic Valve Implantation, Commissural Alignment	40		clinicaltrials.gov
October 10, 2025	NCT07215143	Observational Study to Collect Data of Patient Which Recieving a TAVI in TAVI Procedure	IHF GmbH - Institut für Herzinfarktforschung	Observational	Recruiting	Aortic Valve Stenosis	300	Germany	clinicaltrials.gov
October 3, 2025	NCT07205341	Detecting Changes in Arterial Blood Volume and Cardiac Efficiency	HemoCept Inc.	Observational	Recruiting	Aortic Valve Stenosis	20	United States	clinicaltrials.gov
October 3, 2025	NCT07205068	Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure	University of Tennessee Graduate School of Medicine	Not applicable	Recruiting	Aortic Stenosis	100	United States	clinicaltrials.gov
October 1, 2025	NCT07201363	Biomarkers of Inflammation and Fibrosis in Conduction Disorders After TAVI	Clinical Hospital Center Rijeka	Observational	Recruiting	TAVI(Transcatheter Aortic Valve Implantation), Conduction Disorder, Aortic Stenosis, Permanent Pacemaker Implantation	102	Croatia	clinicaltrials.gov
September 29, 2025	NCT07197736	DELINEATE-Prospective	Columbia University	Observational	Recruiting	Valve Disease, Aortic, Mitral Regurgitation (MR), Aortic Stenosis, Valvular Heart Disease, Tricuspid Regurgitation...	50	United States	clinicaltrials.gov
September 26, 2025	NCT07194265	A Clinical Trial Assessing the Safety and Effectiveness of the DurAVR® THV System	Anteris Technologies Ltd.	Not applicable	Recruiting	Severe Aortic Stenosis, Valve-in-valve Procedures	1,650	Denmark	clinicaltrials.gov
September 26, 2025	NCT07193888	Navitor Japan Study	Abbott Medical Devices	Observational	Recruiting	Severe Aortic Stenosis	100	Japan	clinicaltrials.gov
September 17, 2025	NCT07179302	Pre- and Post-TAVI Patient Assessment: Advancing Outcome Precision in Aortic Valve Therapy	Damanhour University	Observational	Completed	Aortic Valve Stenosis	100	Egypt, Saudi Arabia	clinicaltrials.gov
September 12, 2025	NCT07170306	Cardiac Amyloidosis in Patients With Aortic Stenosis	Shanghai Zhongshan Hospital	Observational	Not yet recruiting	Aortic Stenosis, Transthyretin Amyloid Cardiomyopathy	143		clinicaltrials.gov
August 28, 2025	NCT07145463	Prospective, Multicenter, Randomized Controlled Clinical Study Evaluating the VitaFlow Liberty® Flex Transcatheter Aortic Valve Delivery...	Shanghai Zhongshan Hospital	Not applicable	Recruiting	Aortic Valve Stenosis	232	China	clinicaltrials.gov
August 27, 2025	NCT07144189	AI Assessment of Low-Gradient Aortic Stenosis Severity Based on Echocardiography	National Institute of Cardiology, Warsaw, Poland	Observational	Recruiting	Low-gradient Aortic Stenosis, Aortic Stenosis	300	Poland	clinicaltrials.gov
August 14, 2025	NCT07123766	Clinical Investigation for the PoliaValve Aortic Heart Valve- India	Suzhou Hearthill Medical Technology Co.,LTD	Not applicable	Not yet recruiting	AORTIC VALVE DISEASES, Aortic Valve Stenosis, Aortic Valve Regurgitation	50		clinicaltrials.gov
August 11, 2025	NCT07116551	Early Feasibility Study (EFS) of Abbott's Balloon-expandable (BE) TAVI System for the Treatment of Severe, Symptomatic Aortic Stenosis	Abbott Medical Devices	Not applicable	Active not recruiting	Symptomatic Severe Aortic Stenosis	11	France, United States	clinicaltrials.gov
August 11, 2025	NCT07116265	Perceval Aortic Bioprostheses : Durability Study.	University Hospital, Montpellier	Observational	Completed	Stenoses, Aortic Valve, Aortic Insufficiency, Aortic Diseases	192		clinicaltrials.gov
August 7, 2025	NCT07108478	A Prospective, Multicenter, Observational Study of the Safety and Efficacy of Emergency Transcatheter Aortic Valve Replacement in Patients...	Qilu Hospital of Shandong University	Observational	Not yet recruiting	Severe Aortic Valve Stenosis	35	China	clinicaltrials.gov
August 6, 2025	NCT07107568	Assessment of Coronary Artery Disease Before Transcatheter Aortic Valve Replacement: A Randomized, Multicenter, Non-Inferiority Trial	Medical University Innsbruck	Not applicable	Recruiting	Aortic Valve Stenosis and Insufficiency, Coronary Artery Disease(CAD), Transcatheter Aortic Valve Replacement (TAVR)	700	Austria	clinicaltrials.gov
August 6, 2025	NCT07105501	Atrial Amyloid May Influence Outcomes in Patients Undergoing Surgical Aortic Valve Replacement	Germans Trias i Pujol Hospital	Observational	Completed	Aortic Stenosis, Amyloid	110	Spain	clinicaltrials.gov
July 31, 2025	NCT07097740	Early Feasibility Study of Surgical Implantation of a Polymer Prosthetic Mitral and Aortic Valve	Mitrassist Lifesciences Limited Co., Ltd.	Not applicable	Recruiting	AORTIC VALVE DISEASES, Mitral Valve Disease, Aortic Stenosis, Aortic Regurgitation, Mitral Stenosis, Mitral...	10	China	clinicaltrials.gov
July 29, 2025	NCT07090343	Semaglutide in Patients Undergoing Transcatether Aortic Valve Replacement	Leiden University Medical Center	Phase 3	Not yet recruiting	Aortic Stenosis, Heart Failure	826		clinicaltrials.gov
July 28, 2025	NCT07087379	Perioperative Intensive Statin Therapy for Neuroprotection in TAVR（PISTNT）	Pan Xiangbin	Phase 4	Not yet recruiting	Aortic Stenosis, Cerebral Ischaemic Injury	500		clinicaltrials.gov
July 25, 2025	NCT07086989	Cardiovascular Risk in Children With Chronic Conditions Study	Semmelweis University	Observational	Recruiting	Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)...	300	Hungary	clinicaltrials.gov
July 24, 2025	NCT07082426	Early System Experience With the Abbott Balloon-expandable TAVI System: First-In-Human Study	Abbott Medical Devices	Not applicable	Active not recruiting	Symptomatic Severe Aortic Stenosis	8	Georgia, Uzbekistan	clinicaltrials.gov
July 16, 2025	NCT07068633	Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world Practice	Yonsei University	Observational	Recruiting	Heart Valve Diseases, Aortic Valve Stenosis, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Mitral Valve...	30,000	South Korea	clinicaltrials.gov
July 15, 2025	NCT07065123	Study on Heart Block Risks Using Outcome-Based Modeling	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Observational	Completed	Left Bundle-Branch Block, Aortic Stenosis	112		clinicaltrials.gov
July 11, 2025	NCT07059728	High Flow Nasal Oxygenation in Transcatheter Aortic Valve Replacement Procedures. TAVR-Highflow II	Hospital Clinic of Barcelona	Not applicable	Not yet recruiting	Aortic Stenosis Treated With TAVI, Sedation; Aged; Hemodynamics	452	Spain	clinicaltrials.gov
July 4, 2025	NCT07052071	Impact of Transcatheter Aortic Valve Implantation (TAVI) on the Gut Microbiota in Patients With Aortic Valve Stenosis	Hippocration General Hospital	Observational	Recruiting	Aortic Stenosis, Gut Microbiome, Gut Microbiota, TAVI, TAVI(Transcatheter Aortic Valve Implantation)	40	Greece	clinicaltrials.gov
June 29, 2025	NCT07043075	First-in-Human (FIH) Study on the Feasibility and Safety of the TaviPilot Augmented Reality Guidance Software	Caranx Medical	Not applicable	Not yet recruiting	Aortic Valve Stenosis	10		clinicaltrials.gov
June 29, 2025	NCT07042529	Optimized Expansion of the Implanted Transcatheter Aortic Valve	Ole De Backer	Not applicable	Recruiting	Aortic Stenosis Disease, Valvular Heart Disease	1,010	Belgium, Denmark, Finland, Netherlands, Norway, Sweden	clinicaltrials.gov
June 25, 2025	NCT07035847	Transaxillary TAVR With Solely Echocardiography Guidance	Chinese Academy of Medical Sciences, Fuwai Hospital	Not applicable	Recruiting	Aortic Stenosis	20	China	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Yonsei University	3	November 3, 2026
IRCCS Policlinico S. Donato	3	March 6, 2026
Chinese Academy of Medical Sciences, Fuwai Hospital	3	March 4, 2026
Abbott Medical Devices	3	September 26, 2025
Peijia Medical Technology (Suzhou) Co., Ltd.	2	November 2, 2026
University Hospital of Ferrara	2	October 26, 2026
Erasmus Medical Center	2	October 13, 2026
Braile Biomedica Ind. Com. e Repr. Ltda.	2	September 8, 2026
Istanbul University - Cerrahpasa	2	August 31, 2026
Hospital Clinic of Barcelona	2	July 31, 2026
Eunpyeong St. Mary's Hospital	2	July 17, 2026
Fondazione Policlinico Universitario Agostino Gemelli IRCCS	2	June 4, 2026
Beijing Anzhen Hospital	2	May 26, 2026
Portuguese Association of Interventional Cardiology	2	January 15, 2026
China National Center for Cardiovascular Diseases	2	January 5, 2026
Medical University Innsbruck	2	December 16, 2025
Shanghai Zhongshan Hospital	2	September 12, 2025
Suzhou Hearthill Medical Technology Co.,LTD	2	August 14, 2025
University Hospital, Montpellier	2	August 11, 2025
Semmelweis University	2	July 25, 2025

By phase

Phase	New trials	Latest
Observational	72	November 9, 2026
Not applicable	68	November 3, 2026
Phase 4	7	July 29, 2026
Phase 2	2	July 20, 2026
Phase 3	1	July 29, 2025
Phase 2/3	1	June 3, 2025
Early phase 1	1	May 30, 2025

By country

Country	New trials	Latest
United States	22	November 2, 2026
China	21	November 2, 2026
Germany	13	October 13, 2026
Italy	12	October 26, 2026
Spain	8	July 31, 2026
Netherlands	6	October 13, 2026
Turkey (Türkiye)	6	August 31, 2026
Canada	6	July 31, 2026
Egypt	5	November 9, 2026
France	5	April 9, 2026
Denmark	4	September 1, 2026
Switzerland	4	August 4, 2026
South Korea	4	July 29, 2026
Austria	4	March 17, 2026
Australia	4	February 24, 2026
Sweden	3	March 2, 2026
Poland	3	December 2, 2025
Croatia	2	May 29, 2026
Greece	2	April 9, 2026
Portugal	2	January 15, 2026
Norway	2	January 9, 2026
Thailand	2	December 2, 2025
Japan	2	September 26, 2025
Hungary	2	July 25, 2025
Belgium	2	June 29, 2025

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.