Data / New clinical trials / Anemia, Sickle Cell

Anemia, Sickle Cell trials: 127 new since Nov 2024

Name: New Anemia, Sickle Cell clinical trials
Creator: SpecStream
License: https://creativecommons.org/licenses/by/4.0/

The full list. New Anemia, Sickle Cell clinical trials: 127 rows for $6.35, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. The list gains about 5 rows a month. The new rows come each week by email, $19 a month.

Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The weekly rows run until you cancel, from the link in each delivery. The rows on this page are a sample.

For agents and scripts: this list is ordered at https://specstream.ai/data/clinical-trials/condition/anemia-sickle-cell, and every list with its row count and price is at https://specstream.ai/data/lists.json.

Updated November 9, 2026. Source: ClinicalTrials.gov API v2 (U.S. National Library of Medicine).

127 clinical studies in Anemia, Sickle Cell were first posted on ClinicalTrials.gov from November 14, 2024 to November 9, 2026; 19 have an industry sponsor and 99 are recruiting or about to. The newest, NCT07925372, was posted on November 9, 2026: Acute Pain Management of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease in the... (Central Hospital, Nancy, France).

The request: Every new Anemia, Sickle Cell clinical trial on ClinicalTrials.gov, with the sponsor, phase, sites and the listed contact. $10 of credit on sign-up, no card.

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SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

127New trials
19Industry sponsored
99Recruiting or not yet
November 9, 2026Latest posted

Newest trials

The newest 100 of 127, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

First posted	NCT ID	Title	Sponsor	Phase	Status	Conditions	Enrollment	Countries	Source
November 9, 2026	NCT07925372	Acute Pain Management of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease in the Emergency Department: a Comparative...	Central Hospital, Nancy, France	Observational	Completed	Sickle Cell Disease	92	France	clinicaltrials.gov
November 3, 2026	NCT07911618	Data Collection For Patients With Sickle Cell Disease	M.D. Anderson Cancer Center	Observational	Not yet recruiting	Data Collection, Sickle Cell Disease	500	United States	clinicaltrials.gov
November 2, 2026	NCT07910396	Focused Ultrasound Neuromodulation for Chronic Pain	University of Minnesota	Not applicable	Not yet recruiting	Chronic Pain, Sickle Cell Disease, Chronic Pelvic Pain Syndrome	80	United States	clinicaltrials.gov
October 23, 2026	NCT07892651	MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)	Axiom Bioregistry	Observational	Not yet recruiting	Antiphospholipid (aPL)-Positive, Rheumatic Arthritis, Celiac Disease, Focal Segmental Glomerulosclerosis (FSGS)...	5,000	Jordan	clinicaltrials.gov
October 16, 2026	NCT07877753	Evolution of Sickle Cell Maculopathy	Christophe Orssaud	Observational	Completed	Sickle Cell Disease, Macula Thickening, Macula Abnormality	34	France	clinicaltrials.gov
October 15, 2026	NCT07875777	Self-administered Acupressure in Patients With Sickle Cell Disease	University of Cincinnati	Not applicable	Not yet recruiting	Sickle Cell Disease (SCD)	300	United States	clinicaltrials.gov
October 8, 2026	NCT07865039	Inflammatory Markers and Pain in Sickle Cell Disease	Assiut University	Observational	Not yet recruiting	Sickle Cell Disease	75	Egypt	clinicaltrials.gov
October 1, 2026	NCT07852442	Comparison of Thrombin Generation, Platelet Activation and Aggregation Profiles in Patients With Sickle Cell Disease Depending on Their SS...	Centre Hospitalier Universitaire de la Guadeloupe	Observational	Not yet recruiting	Sickle Cell Disease, Venous Thromboembolism	60	France, Guadeloupe	clinicaltrials.gov
September 18, 2026	NCT07826988	Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive Crisis	Assistance Publique - Hôpitaux de Paris	Phase 4	Not yet recruiting	Sickle Cell Disease, Vaso-occlusive Crisis	400		clinicaltrials.gov
September 3, 2026	NCT07802210	Effectiveness of Innovative Educational Methods in Empowering Children With Sickle Cell Disease	Aula Ibrahim abd alrazak	Not applicable	Not yet recruiting	Sickle Cell Anemia in Children	120	Iraq	clinicaltrials.gov
September 2, 2026	NCT07800247	Hemoglobin Disorders in Egypt: Sickle Cell Disease Ain Shams University Institutional Registry	Ain Shams University	Observational	Recruiting	Sickle Cell Disease (SCD)	400	Egypt	clinicaltrials.gov
September 2, 2026	NCT07799571	Buprenorphine for the Management of Pain in Children With Sickle Cell Disease	Natasha Archer	Phase 1	Not yet recruiting	Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis, Sickle Cell Anemia Crisis, Sickle Cell Anemia in...	25	United States	clinicaltrials.gov
September 1, 2026	NCT07797582	MBI for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease	University of Illinois Chicago	Not applicable	Not yet recruiting	Chronic Pain, Sickle Cell Disease, Sleep	48		clinicaltrials.gov
August 24, 2026	NCT07782489	Pleuropulmonary Ultrasound Imaging in Patients With Sickle Cell Disease in a Vaso-occlusive Crisis. "ECHODREP"	Assistance Publique - Hôpitaux de Paris	Observational	Not yet recruiting	Sickle Cell Disease (SCD), Vaso-Occlusive Crises, Acute Chest Syndrome	200		clinicaltrials.gov
August 20, 2026	NCT07776444	Cerebrovascular Reactivity Measurements With High-Density Diffuse Optical Tomography	Washington University School of Medicine	Not applicable	Recruiting	Sickle Cell Disease, Cerebral Stroke	120	United States	clinicaltrials.gov
August 7, 2026	NCT07753681	Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System	Centre for Infectious Disease Research in Zambia	Observational	Recruiting	Cardiac Diseases, Sickle Cell Disease, Hypertension, Diabetes Mellitus, Heart Failure, Congenital Heart Disease...	2,084	Zambia	clinicaltrials.gov
August 7, 2026	NCT07752043	Standard of Care Comparative Arm of Phase 1/2 Gene Therapy Trial DREPAMIR" in Severe Sickle Cell Disease Patients	Assistance Publique - Hôpitaux de Paris	Not applicable	Not yet recruiting	Sickle Cell Disease (SCD), Vaso-occlusive Events	30	France	clinicaltrials.gov
July 22, 2026	NCT07721155	Objective Neurocognitive Assessment of Young Children With Sickle Cell Disease by Eye-Tracking	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Observational	Completed	Sickle Cell Disease, Sickle Cell, Neurocognition, Child	93	Netherlands	clinicaltrials.gov
July 22, 2026	NCT07719972	Universal Newborn Screening For Sickle Cell Disease In Mozambique	St. Jude Children's Research Hospital	Not applicable	Not yet recruiting	Sickle Cell Disease	6,750		clinicaltrials.gov
July 16, 2026	NCT07708714	Optimizing Hydroxyurea Therapy in Children With Sickle Cell Anemia In Malaria Endemic Areas: The NOHARM Maximum Tolerated Dose (MTD) Study	Children's Hospital Medical Center, Cincinnati	Phase 1/2	Recruiting	Sickle Cell Disease, Sickle Cell Anemia in Children	250	Uganda	clinicaltrials.gov
July 16, 2026	NCT07708350	Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease	Daniel Bauer	Phase 1	Recruiting	Sickle Cell Disease, Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0)	5	United States	clinicaltrials.gov
July 14, 2026	NCT07703566	CPAP for Hypoxemic Acute Chest Syndrome in Sickle Cell Disease	Assistance Publique - Hôpitaux de Paris	Not applicable	Not yet recruiting	Sickle Cell Disease (SCD), Acute Chest Syndrome (ACS)	140		clinicaltrials.gov
July 6, 2026	NCT07682662	Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis	University of Mississippi Medical Center	Phase 4	Not yet recruiting	Vaso-Occlusive Pain Episode in Sickle Cell Disease, Sickle Cell Disease (SCD)	400	United States	clinicaltrials.gov
June 29, 2026	NCT07674277	Virtual Reality for SCD VOC	University of Maryland, Baltimore	Not applicable	Recruiting	Sickle Cell Disease	50	United States	clinicaltrials.gov
June 18, 2026	NCT07656415	A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD)	Agios Pharmaceuticals, Inc.	Phase 3	Recruiting	Sickle Cell Disease	159	United States	clinicaltrials.gov
June 15, 2026	NCT07648043	Feasibility and Acceptability of Amani	Massachusetts General Hospital	Phase 1/2	Not yet recruiting	Sickle Cell Disease	40	United States	clinicaltrials.gov
June 11, 2026	NCT07640815	Expanded Access Protocol for Gene Therapy Utilizing shmiR Lentivirus Vector to Induce Fetal Hemoglobin in Sickle Cell Disease	David Williams	Not applicable	Temporarily not available	Sickle Cell Disease	Not listed	United States	clinicaltrials.gov
June 10, 2026	NCT07639008	Epidemiology of Invasive Bacterial Infections in Children With Sickle Cell Disease in France Between 2020 and 2025	Assistance Publique - Hôpitaux de Paris	Observational	Not yet recruiting	Sickle Cell Disease (SCD), Invasive Bacterial Infections	350	France	clinicaltrials.gov
June 1, 2026	NCT07616154	Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease	St. Jude Children's Research Hospital	Phase 2	Recruiting	Sickle Cell Disease	45	United States	clinicaltrials.gov
May 27, 2026	NCT07610239	Evaluation of an Information Management and Communication System for Population-wide Point-of-Care Infant Sickle Cell Disease Screening	Makerere University	Not applicable	Recruiting	Sickle Cell Disease	24,000	Uganda	clinicaltrials.gov
May 20, 2026	NCT07599176	Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors	National Heart, Lung, and Blood Institute (NHLBI)	Phase 1/2	Recruiting	Sickle Cell Disease, Beta-thalassemia	90	United States	clinicaltrials.gov
May 5, 2026	NCT07566494	Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease	National Heart, Lung, and Blood Institute (NHLBI)	Phase 1	Recruiting	Sickle Cell Disease, Hemolytic Anemia	25	United States	clinicaltrials.gov
May 1, 2026	NCT07562451	Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing	Emory University	Not applicable	Recruiting	Sickle Cell Disease	25	United States	clinicaltrials.gov
April 28, 2026	NCT07554547	Crizanlizumab Pregnancy Outcomes Intensive Monitoring	Novartis Pharmaceuticals	Observational	Completed	Sickle Cell Disease	13	Switzerland	clinicaltrials.gov
April 21, 2026	NCT07543289	Hydroxyurea Optimisation in Sickle Cell Disease	Ochuko Orherhe	Observational	Recruiting	Sickle Cell Disease	100	Nigeria	clinicaltrials.gov
April 20, 2026	NCT07540767	Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease	Connecticut Children's Medical Center	Not applicable	Not yet recruiting	Sickle Cell Disease, Sickle Cell Anemia in Children, Sickle Cell Disease (SCD), Sickle Cell, Sickle Cell Anemia (HbSS)	30	United States	clinicaltrials.gov
April 16, 2026	NCT07532564	Risk Factors, Costs, and Impacts of ED Boarding	University of Maryland, Baltimore	Observational	Completed	Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease), Sepsis, Hypertension...	30,486	United States	clinicaltrials.gov
April 15, 2026	NCT07530965	Omega-3-Fatty Acids in Children With Sickle Cell Disease	University of Alabama at Birmingham	Not applicable	Not yet recruiting	Sickle Cell Disease (SCD)	20		clinicaltrials.gov
March 27, 2026	NCT07498309	Evaluation of the Efficacy of Iloprost in the Management of Vaso-occlusive Crises in Adult Patients With Sickle Cell Disease	University Hospital, Rouen	Phase 3	Not yet recruiting	Vaso-Occlusive Crises, Sickle Cell Disease	144	France	clinicaltrials.gov
March 23, 2026	NCT07488520	Integrating Point of Care Testing (POCT) For Newborn Screening and Early Care for Sickle Cell Disease in Yopougon, Côte d'Ivoire	Swiss Tropical & Public Health Institute	Phase 4	Recruiting	Sickle Cell Disease (SCD)	120	Côte d’Ivoire	clinicaltrials.gov
March 23, 2026	NCT07488091	Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana	University of Ghana Medical School	Not applicable	Recruiting	Sickle Cell Disease and Pregnancy	198	Ghana	clinicaltrials.gov
March 4, 2026	NCT07450430	Optimal Timing of Ketamine Initiation for SCD Pain	Boston Children's Hospital	Phase 3	Not yet recruiting	Sickle Cell Disease, Sickle Cell Crisis	90	United States	clinicaltrials.gov
March 2, 2026	NCT07442851	SickleFit Exercise and Nutrition Study	Duke University	Not applicable	Recruiting	Sickle Cell Disease, Aging	40	United States	clinicaltrials.gov
February 27, 2026	NCT07436767	Safety and Efficacy of KL003 Cell Injection in Severe Sickle Cell Disease	Institute of Hematology & Blood Diseases Hospital, China	Not applicable	Suspended	Sickle Cell Disease	3	China	clinicaltrials.gov
February 25, 2026	NCT07432867	Efficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected...	Assistance Publique - Hôpitaux de Paris	Phase 1/2	Recruiting	Sickle Cell Disease	15	France	clinicaltrials.gov
February 24, 2026	NCT07431398	Single-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell Disease	Fulcrum Therapeutics	Phase 1	Terminated	Sickle Cell Disease	13	United States	clinicaltrials.gov
February 11, 2026	NCT07402811	Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease	University of Illinois Chicago	Not applicable	Completed	Chronic Pain, Sickle Cell Disease, Sleep Disturbance	25	United States	clinicaltrials.gov
February 11, 2026	NCT07401823	Open-Label Extension Study to Pioneer Study 6058-SCD-101	Fulcrum Therapeutics	Phase 2	Terminated	Sickle Cell Disease	1	United States	clinicaltrials.gov
February 6, 2026	NCT07392216	Functional Ovarian Reserve in Sickle Cell Disease	St. Jude Children's Research Hospital	Observational	Recruiting	Sickle Cell Disease	440	United States	clinicaltrials.gov
January 28, 2026	NCT07373639	A Long-term Follow-up Study in Patients Who Received BEAM-101	Beam Therapeutics Inc.	Observational	Recruiting	Hemoglobinopathy, Sickle Cell Disease	50	United States	clinicaltrials.gov
January 27, 2026	NCT07369024	Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults	Mohsen Saidinejad	Phase 2	Recruiting	Sickle Cell Disease, Vaso-Occlusive Pain Episode in Sickle Cell Disease, Ketamine Infusion, Pain Management...	120	United States	clinicaltrials.gov
January 21, 2026	NCT07356050	Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell...	Children's Hospital Medical Center, Cincinnati	Observational	Recruiting	Sickle Cell Disease, Measles Vaccination, Sickle Cell Anemia	130	Ghana, Tanzania, United States	clinicaltrials.gov
January 14, 2026	NCT07341022	STEM CELL MOBILIZATION WITH HIGH-DOSE PLERIXAFOR IN PATIENTS WITH SICKLE CELL DISEASE	Hospital Israelita Albert Einstein	Phase 1/2	Not yet recruiting	Sickle Cell Disease	12		clinicaltrials.gov
January 5, 2026	NCT07316478	Stress Management and Mindfulness Intervention for Patients With Sickle Cell Disease	University of Pennsylvania	Not applicable	Recruiting	Sickle Cell Disease	50	United States	clinicaltrials.gov
December 26, 2025	NCT07305181	Prevalence of Abnormal Haemoglobin Variants in Metropolitan Chattogram, Bangladesh	Bangladesh Bioscience Research Group	Observational	Completed	HbE Trait, Hemoglobinopathies	8,400	Bangladesh	clinicaltrials.gov
December 15, 2025	NCT07282210	Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype	Biossil Inc.	Phase 2	Recruiting	Sickle Cell Disease, Sickle Cell Anaemia, Sickle Cell Anemia	65	Canada	clinicaltrials.gov
December 11, 2025	NCT07277023	The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell...	Centre Hospitalier Universitaire de la Guadeloupe	Not applicable	Completed	Sickle Cell Anemia	49	Guadeloupe	clinicaltrials.gov
December 10, 2025	NCT07274254	Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease	Nantes University Hospital	Phase 3	Recruiting	Vaso-Occlusive Pain Episode in Sickle Cell Disease	104	France, Guadeloupe	clinicaltrials.gov
November 26, 2025	NCT07252050	Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease	Arkansas Children's Hospital Research Institute	Phase 1/2	Recruiting	Sickle Cell Disease, Hematopoetic Stem Cell Transplant, Haploidentical Hematopoietic Stem Cell Transplant...	24	United States	clinicaltrials.gov
November 25, 2025	NCT07247188	Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease	Sanofi	Phase 3	Recruiting	Sickle Cell Disease	100	Dominican Republic, United States	clinicaltrials.gov
November 24, 2025	NCT07246265	Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care	University Hospital, Tours	Not applicable	Recruiting	Sickle Cell Disease, Glomerular Hyperfiltration, Sickle Cell Nephropathy, Vaso-Occlusive Crises, Acute Chest Syndrome	100	France	clinicaltrials.gov
November 10, 2025	NCT07226219	Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease	St. Jude Children's Research Hospital	Phase 1	Recruiting	Sickle Cell Disease, Executive Dysfunction, Cognitive Impairment, Attention Deficit/Hyperactivity Disorder (ADHD)	72	United States	clinicaltrials.gov
November 4, 2025	NCT07224360	Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)	CSL Behring	Phase 2	Recruiting	Sickle Cell Disease	63	Belgium, France, Italy, Netherlands, Turkey (Türkiye), United Kingdom, United...	clinicaltrials.gov
October 30, 2025	NCT07222475	Writing Relaxing Beats in Adolescents Who Have Sickle Cell Disease	Mayo Clinic	Not applicable	Recruiting	Sickle Cell Disease	30	United States	clinicaltrials.gov
October 3, 2025	NCT07206095	Integrative Diagnosis for SCD and Other RADs	Hospital Universitari Vall d'Hebron Research Institute	Observational	Recruiting	Sickle Cell Disease, Thalassaemia, Congenital Dyserythropoietic Anemia (CDA), Enzyme Disorder; Anemia, Spherocytosis...	200	Spain	clinicaltrials.gov
October 1, 2025	NCT07200869	Outcomes of Vaso-occlusive Crisis in Pediatric Sickle Cell Disease	Assiut University	Observational	Not yet recruiting	Sickle Cell Disease, Vaso-occlusive Crisis	25	Egypt	clinicaltrials.gov
September 24, 2025	NCT07190001	YOLT-204 in Patients With Hemoglobinopathies	Guangzhou Women and Children's Medical Center	Early phase 1	Not yet recruiting	Hemoglobinopathies (Transfusion-dependent β-thalassemia and Sickle Cell Disease)	18	China	clinicaltrials.gov
September 23, 2025	NCT07188766	Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive Crisis	Imam Abdulrahman Bin Faisal University	Not applicable	Recruiting	SCD, Vaso Occlussive Crisis	394	Saudi Arabia	clinicaltrials.gov
September 23, 2025	NCT07187973	A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)	Disc Medicine, Inc	Phase 1	Recruiting	Sickle Cell Disease	24	United States	clinicaltrials.gov
September 18, 2025	NCT07180836	Prevalence and Hematological Characteristics of Hemoglobinopathies	Bacha Khan Medical College	Observational	Completed	Hemoglobinopathies	839	Pakistan	clinicaltrials.gov
September 16, 2025	NCT07177300	Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)	Children's Hospital Medical Center, Cincinnati	Phase 4	Recruiting	Sickle Cell Anemia (HbSS), Sickle-β0-thalassemia (HbSβ0)	50	United States	clinicaltrials.gov
September 16, 2025	NCT07175051	Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin	University of Illinois Chicago	Phase 2	Recruiting	Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0), Albuminuria	20	United States	clinicaltrials.gov
September 11, 2025	NCT07168447	Transfusion Exchanges and Cognition in Sickle Cell Disease	Centre Hospitalier St Anne	Observational	Not yet recruiting	Drepanocytosis, Chronic Neurological Deficiency	85	France	clinicaltrials.gov
September 4, 2025	NCT07155031	Biotin-Acridine Red Cell Exchange Kinetics	Cerus Corporation	Phase 2	Withdrawn	Sickle Cell Disease	0		clinicaltrials.gov
August 28, 2025	NCT07145411	HPC Offered for PRESERVE Expansion	Ossium Health, Inc.	Observational	Recruiting	Bone Marrow Transplant (BMT)	10	United States	clinicaltrials.gov
August 12, 2025	NCT07116772	Serial Assessment of Fertility Experiences	Children's Hospital Medical Center, Cincinnati	Observational	Recruiting	Sickle Cell Anemia	250	Dominican Republic, Jamaica, Tanzania	clinicaltrials.gov
July 30, 2025	NCT07094646	Full Assessment of Clinical Transfusion Support	Children's Hospital Medical Center, Cincinnati	Observational	Completed	Sickle Cell Anemia, Blood Transfusion, Malaria Parasitaemia	250	Uganda	clinicaltrials.gov
July 29, 2025	NCT07090668	Trans-auricular Nerve Stimulation as an Innovative Approach to the Treatment of Pain in Pediatric Patients Suffering From Sickle Cell...	Emory University	Not applicable	Recruiting	Sickle Cell Disease	20	United States	clinicaltrials.gov
July 24, 2025	NCT07083531	Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait	UConn Health	Observational	Recruiting	Sickle Cell Disease, Sickle Cell Trait	50	United States	clinicaltrials.gov
July 15, 2025	NCT07066072	The Radiofrequency Therapy in Management of Sickle Cell Disease Chronic Pain RCT Tested the Effect of TECAR Therapy on Sickle Cell Disease...	Cairo University	Not applicable	Completed	the Use of Radiofrequency Ablation in Form of TECAR(Capacitive and Resistive Transfer Energy) in Chronic Pain of Sickle...	170	Egypt	clinicaltrials.gov
July 14, 2025	NCT07064174	Sickle Cell Kidney Biorepository	University of Texas Southwestern Medical Center	Observational	Recruiting	Sickle Cell Trait, Sickle Cell Disease (SCD), Chronic Kidney Disease	800	United States	clinicaltrials.gov
June 25, 2025	NCT07037706	Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective Study	Centre Hospitalier de Saint-Denis	Observational	Completed	Sickle Cell Disease, Acute Chest Syndrome, Glucose-6-Phosphate Dehydrogenase Deficiency, Anti-Bacterial Agents...	250	France	clinicaltrials.gov
June 17, 2025	NCT07023666	Early Screening and Treatment of Heart Complication in Sickle Cell Disease	Inova Health Care Services	Phase 2	Recruiting	Sickle Cell Disease	100	United States	clinicaltrials.gov
June 15, 2025	NCT07023029	A Study on the Effect of Etavopivat on Heart Rhythm in Healthy Participants	Novo Nordisk A/S	Phase 1	Completed	Healthy Volunteers, Sickle Cell Disease, Thalassemia	33	United States	clinicaltrials.gov
June 11, 2025	NCT07015684	131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)	Columbia University	Phase 1	Recruiting	Sickling Disorder Due to Hemoglobin S	24	United States	clinicaltrials.gov
June 3, 2025	NCT07001631	Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Not applicable	Recruiting	Sickle Cell Disease, Pain, Pain, Chronic Disease	40	Netherlands	clinicaltrials.gov
June 3, 2025	NCT07001189	Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients	Centre Hospitalier Universitaire de la Guadeloupe	Observational	Recruiting	Sickle Cell, Sickle Cell Disease, Vaso-Occlusive Crises	34	Guadeloupe	clinicaltrials.gov
June 3, 2025	NCT07000747	Molecular and Cellular Basis of Severe Forms of Dengue in Sickle Cell Patients	Centre Hospitalier Universitaire de la Guadeloupe	Observational	Recruiting	Dengue (Virus); Fever, Sandfly, Sickle Cell Disease	130	Guadeloupe	clinicaltrials.gov
June 2, 2025	NCT07000318	CS-206 in Patients With Sickle Cell Disease	Children's Hospital of Fudan University	Early phase 1	Not yet recruiting	Sickle Cell Disease	5	China	clinicaltrials.gov
May 25, 2025	NCT06989567	A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute...	Asklepion Pharmaceuticals, LLC	Phase 3	Not yet recruiting	Sickle Cell Disease	120	United States	clinicaltrials.gov
May 23, 2025	NCT06986837	Role of Inflammasome in Platelet Activation in Sickle Cell Disease Patient	Centre Hospitalier Universitaire de la Guadeloupe	Observational	Completed	Sickle Cell Disease	92	Guadeloupe	clinicaltrials.gov
May 20, 2025	NCT06979492	Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease	Emory University	Phase 4	Withdrawn	Sickle Cell Disease, Pregnancy Related	0	United States	clinicaltrials.gov
May 16, 2025	NCT06975865	The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease	Sanofi	Phase 3	Recruiting	Sickle Cell Disease	192	Belgium, Brazil, France, Germany, Greece, Israel, Italy, Netherlands, Oman...	clinicaltrials.gov
April 25, 2025	NCT06944067	Study to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell Disease	National Human Genome Research Institute (NHGRI)	Observational	Recruiting	Sickle Cell Disease	50	United States	clinicaltrials.gov
April 23, 2025	NCT06941389	Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric...	University of Rochester	Observational	Recruiting	Sickle Cell Disease (SCD)	480	Canada, United States	clinicaltrials.gov
April 23, 2025	NCT06939933	Effect of Aquatic Exercises on Muscle Strength and Quality of Life in Children With Sickle Cell Anemia	Kafrelsheikh University	Not applicable	Completed	Sickle Cell Anemia in Children	50	Egypt	clinicaltrials.gov
April 16, 2025	NCT06930703	Cannabidiol in Sickle Cell Disease	Icahn School of Medicine at Mount Sinai	Phase 1/2	Recruiting	Sickle Cell Disease	52	United States	clinicaltrials.gov
April 13, 2025	NCT06924970	A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)	Agios Pharmaceuticals, Inc.	Phase 2	Active not recruiting	Sickle Cell Disease	59	Belgium, Canada, France, Ireland, Netherlands, United Kingdom, United States	clinicaltrials.gov
April 11, 2025	NCT06923111	PASS of Xromi Comparing Safety and Effectiveness in Children Under 2 Years With Sickle Cell Disease [PRECISE PASS]	Nova Laboratories Limited	Observational	Recruiting	Sickle Cell Disease	180	Germany, United Kingdom	clinicaltrials.gov
April 9, 2025	NCT06919224	Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease	Ohio State University	Not applicable	Recruiting	Sickle Cell Disease	287	United States	clinicaltrials.gov

Sponsors posting most

Sponsor	New trials	Latest
Assistance Publique - Hôpitaux de Paris	9	September 18, 2026
Centre Hospitalier Universitaire de la Guadeloupe	6	October 1, 2026
St. Jude Children's Research Hospital	5	July 22, 2026
Children's Hospital Medical Center, Cincinnati	5	July 16, 2026
University of Illinois Chicago	4	September 1, 2026
Emory University	4	May 1, 2026
Hospital Universitari Vall d'Hebron Research Institute	3	October 3, 2025
University of Cincinnati	2	October 15, 2026
Assiut University	2	October 8, 2026
Washington University School of Medicine	2	August 20, 2026
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	2	July 22, 2026
University of Maryland, Baltimore	2	June 29, 2026
Agios Pharmaceuticals, Inc.	2	June 18, 2026
National Heart, Lung, and Blood Institute (NHLBI)	2	May 20, 2026
Fulcrum Therapeutics	2	February 24, 2026
Sanofi	2	November 25, 2025
CSL Behring	2	November 4, 2025
Cairo University	2	July 15, 2025
Centre Hospitalier de Saint-Denis	2	June 25, 2025
University Hospital, Toulouse	2	March 20, 2025

By phase

Phase	New trials	Latest
Not applicable	43	November 2, 2026
Observational	42	November 9, 2026
Phase 2	11	June 1, 2026
Phase 1	8	September 2, 2026
Phase 3	8	June 18, 2026
Phase 1/2	7	July 16, 2026
Phase 4	5	September 18, 2026
Early phase 1	2	September 24, 2025
Phase 2/3	1	January 7, 2025

By country

Country	New trials	Latest
United States	62	November 3, 2026
France	21	November 9, 2026
Guadeloupe	7	October 1, 2026
Egypt	6	October 8, 2026
Netherlands	6	July 22, 2026
United Kingdom	6	November 4, 2025
Canada	4	December 15, 2025
Spain	4	October 3, 2025
Uganda	3	July 16, 2026
China	3	February 27, 2026
Belgium	3	November 4, 2025
Italy	3	November 4, 2025
Turkey (Türkiye)	3	November 4, 2025
Ghana	2	March 23, 2026
Tanzania	2	January 21, 2026
Dominican Republic	2	November 25, 2025
Saudi Arabia	2	September 23, 2025
Germany	2	May 16, 2025
Jordan	1	October 23, 2026
Iraq	1	September 3, 2026
Zambia	1	August 7, 2026
Switzerland	1	April 28, 2026
Nigeria	1	April 21, 2026
Côte d’Ivoire	1	March 23, 2026
Bangladesh	1	December 26, 2025

Where the register publishes

U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.