Data / Investment advisers / Massachusetts / Opaleye Management Inc.
Opaleye Management Inc., Boston, MA: $803 million AUM, SEC registered investment adviser
Updated November 7, 2026. Source: the SEC's Form ADV data files for investment advisers.
Opaleye Management Inc. is an SEC registered investment adviser with its main office in Boston, Massachusetts and reports $803 million in regulatory assets under management in its Form ADV filed February 19, 2026. Its clients include pooled investment vehicles and corporations and other businesses. It is paid through a percentage of assets under management and performance based fees. It advises 1 private fund.
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- Registration
- SEC registered investment adviser
- CRD number
- 124513
- SEC file number
- 801-78700
- SEC status
- Approved, effective October 29, 2013
- Main office
- One Boston Place 26th Floor, Boston, MA 02108
- Phone
- (617) 229-5085
- Regulatory AUM
- $802,773,181 in the Form ADV filed February 19, 2026
- Discretionary AUM
- $802,773,181
- Accounts
- 2
- Employees
- 4, of which 4 give investment advice
- Form of organization
- Corporation
- Paid through
- a percentage of assets under management, performance based fees
- Private funds
- 1: 1 hedge fund
- Gross assets of private funds
- $789,221,306
- Other offices
- 1
- Form ADV Item 11 disclosures
- Reported: other federal, state or foreign regulatory actions
- Latest Form ADV filing
- February 19, 2026
- SEC record
- Investment Adviser Public Disclosure
Clients
Client types the adviser reports in Form ADV item 5.D, with the AUM it attributes to each.
| Client type | Clients | AUM |
|---|---|---|
| Pooled investment vehicles | 1 | $789.2 million |
| Corporations or other businesses | 1 | $13.6 million |
AUM in the SEC's monthly files
Each change in the AUM the adviser reported across the monthly SEC files held here, with the first file that shows the new value.
| First in the file of | AUM | Form ADV filed |
|---|---|---|
| March 2, 2026 | $802.8 million | February 19, 2026 |
| December 1, 2025 | $639.6 million | July 29, 2025 |
Other advisers in Boston
| Adviser | City | AUM | Private funds | Source |
|---|---|---|---|---|
| Denali Growth Partners | Boston | $830.6 million | 7 | adviserinfo.sec.gov |
| New Heritage Capital, LLC | Boston | $830 million | 10 | adviserinfo.sec.gov |
| J.P. Marvel Wealth Management, Inc. | Boston | $820.7 million | Not listed | adviserinfo.sec.gov |
| Clear Brook Advisors, Inc. | Boston | $817.8 million | Not listed | adviserinfo.sec.gov |
| Northstar Asset Management, Inc | Boston | $805.9 million | Not listed | adviserinfo.sec.gov |
| Astira Capital Partners LP | Boston | $777.3 million | 2 | adviserinfo.sec.gov |
| Stride Consumer | Boston | $740.3 million | 5 | adviserinfo.sec.gov |
| Bayhawk Capital LP | Boston | $730.8 million | 5 | adviserinfo.sec.gov |
Also on SpecStream
- Investment advisers in Boston, MA
- Investment advisers in Massachusetts
- Advisers with $500 million to $1 billion in AUM
- Advisers serving pooled investment vehicles
- Advisers serving corporations and other businesses
- Advisers that manage private funds
- Opaleye Management Inc. on the SEC's adviser search
Public data published by the US Securities and Exchange Commission (US government work). Advisers report these values themselves in Form ADV, and neither the SEC nor the states approve or guarantee them. AUM is regulatory assets under management as the adviser reported it in Form ADV item 5.F, which can differ from the AUM a firm quotes elsewhere. Exempt reporting advisers do not report AUM. Office address, phone and website are the adviser's main office as filed; a firm that files its main office as a private residence shows no street address or phone. An Item 11 disclosure is a reported event, not a finding about the firm today. Details for each firm are on the SEC's Investment Adviser Public Disclosure site. This page uses SEC data and is not endorsed or certified by the SEC. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.