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Data / Research funding / Stem Cell Research - Nonembryonic - Human

Stem Cell Research - Nonembryonic - Human: 1,172 NIH awards ($1.1B) to 288 organizations

1,172 NIH awards ($1.1B) in the NIH spending category Stem Cell Research - Nonembryonic - Human, to 288 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 1,172 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Nebraska Research Network in Functional GenomicsNIHNational Institute of General Medical Sciences2021 to 2025$20,833,603September 30, 2001April 30, 2026SORGEN, PAUL Lreporter.nih.gov
Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$19,528,719June 1, 1997June 30, 2028STEIDL, ULRICHreporter.nih.gov
Baylor College of Medicine Cancer Center - Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$19,034,443July 1, 2007June 30, 2030REDDY, PAVANreporter.nih.gov
The University of Kansas Cancer CenterNIHNational Cancer Institute2021 to 2025$13,943,269July 11, 2012June 30, 2027JENSEN, ROY A.reporter.nih.gov
Inherited T cell defects: Diagnosis, Mechanisms and TreatmentsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$9,040,281September 8, 2020August 31, 2025MARSON, ALEXANDERreporter.nih.gov
Therapeutic gene editing and multimodal imaging in juvenile macular degenerationNIHNational Eye Institute2021 to 2024$8,710,741June 1, 2020May 31, 2026TSANG, STEPHEN Hreporter.nih.gov
Molecular Circuits in the Hematopoietic Stem Cell NicheNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$6,422,507August 15, 2020May 31, 2025DALEY, GEORGE Qreporter.nih.gov
A regulome and transcriptome atlas of fetal and adult human neurogenesisNIHNational Institute of Mental Health2021$5,548,451September 20, 2021September 19, 2025ROUSSOS, PANAGIOTISreporter.nih.gov
Actin assembly and clathrin-mediated endocytosis in yeast and mammalsNIHNational Institute of General Medical Sciences2021 to 2025$5,442,792July 1, 2016June 30, 2026DRUBIN, DAVID Greporter.nih.gov
A Human iPSC-based Cell Therapy for Canavan DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$5,276,950June 15, 2021May 31, 2027SHI, YANHONGreporter.nih.gov
The stromal microenvironment as a co-organizer of bladder carcinogenesis and progressionNIHNational Cancer Institute2023 to 2025$5,126,849September 22, 2022August 31, 2027CHAN, KEITH SYSONreporter.nih.gov
IND Enabling Studies for RASRx 1902, a novel Mas receptor agonist, for treatment of cognitive impairment in patients at risk for Alzheimer's disease.NIHNational Institute on Aging2021 to 2023$4,958,940May 1, 2020April 30, 2026RODGERS, KATHLEEN E.reporter.nih.gov
Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes MellitusNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$4,582,323September 20, 2018July 31, 2024STAHL, ANDREASreporter.nih.gov
Early Pathogenesis of Cystic Fibrosis Related DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$4,452,977April 30, 2021March 31, 2024ENGELHARDT, JOHN Freporter.nih.gov
Human Microphysiology Systems Disease Model of Type 2 Diabetes Starting with Liver and pancreatic IsletsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$4,324,679September 20, 2018July 31, 2023TAYLOR, D. LANSINGreporter.nih.gov
A generalizable framework for linking single-cell genomic states with cell fate outcomes in hematopoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$4,203,696August 15, 2020May 31, 2025GRIMES, H. LEIGHTONreporter.nih.gov
Small molecule targeting an epigenetic regulator for the treatment of osteoarthritisNIHNational Institute on Aging2021 to 2024$4,178,124September 30, 2021May 2, 2025ADORNO, MADDALENAreporter.nih.gov
BMT Survivor Study-2 (BMTSS-2)NIHNational Cancer Institute2021 to 2023$3,811,745April 1, 2019March 31, 2025BHATIA, SMITAreporter.nih.gov
Cardiac Lineage-Specific Molecular Mechanisms of Heart FailureNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,682,052February 1, 2021January 31, 2025CHI, NEIL Creporter.nih.gov
1/2 Allogeneic Human Mesenchymal Stem Cell (MSC) Injection in Patients with Hypoplastic Left Heart Syndrome: A Phase IIb Clinical TrialNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,521,212September 15, 2020August 31, 2025BERGER, STUARTreporter.nih.gov
Development of a Clinical Hemoglobin ModulatorNIHNational Heart, Lung, and Blood Institute2021 to 2022$3,473,811June 1, 2020May 31, 2024PERRINE, SUSAN PARKreporter.nih.gov
Immunobiology of Lung Injury and FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,455,443January 21, 2019December 31, 2024MOORE, BETHANY B.reporter.nih.gov
Modulating Stochastic Gene Expression for Cell-fate Control and TherapeuticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,366,623June 1, 2014August 10, 2024WEINBERGER, LEOR Sreporter.nih.gov
Vascular smooth muscle cell heterogeneity and diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,305,617March 1, 2021December 31, 2025SIMONS, MICHAELreporter.nih.gov
Protecting colonic mucus to mitigate acute intestinal graft-versus-host diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,218,917August 15, 2015June 30, 2026JENQ, ROBERTreporter.nih.gov
Technology-Enabled Activation of Skin Cancer Screening for Hematopoietic Cell Transplantation Survivors and their Primary Care ProvidersNIHNational Cancer Institute2021 to 2024$3,192,137April 1, 2020March 31, 2026ARMENIAN, SAROreporter.nih.gov
Isolation, characterization and translational development of glioma stem cellsNIHNational Cancer Institute2021 to 2023$3,189,696February 1, 2017January 31, 2025PARADA, LUIS FERNANDOreporter.nih.gov
Modeling intestinal dysfunction in HIV infection with organoid technologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,127,465January 10, 2020December 31, 2025OTT, MELANIE MARIAreporter.nih.gov
Multimodal Analysis of Gestational Health and Placental Injury in Opioid-Affected PregnanciesNIHNational Institute on Drug Abuse2023$3,092,159August 15, 2023July 30, 2026OUYANG, YINGSHIreporter.nih.gov
Therapeutic Anti-HIV Chimeric Antigen Receptors Via Stem Cell DeliveryNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,081,124January 16, 2020December 31, 2024YANG, OTTO Oreporter.nih.gov
Promoting Brain Resilience to Alzheimer's NeuropathologyNIHNational Institute on Aging2021 to 2024$3,062,659August 1, 2020April 30, 2026TAGLIALATELA, GIULIOreporter.nih.gov
MIDAS: MIcroangiopathy, endothelial Damage in Adults undergoing Stem cell transplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,957,506August 20, 2020July 31, 2026VASU, SUMITHIRAreporter.nih.gov
Investigating the effectiveness of COVID-19 testing choices, community engagement, and culturally-embedded mHealth literacy delivery in a medically-underserved, community-based sampleNIHNational Institute of Environmental Health Sciences2021 to 2022$2,906,922November 11, 2020July 31, 2023AL-HENDY, AYMANreporter.nih.gov
Using donor dendritic cells to optimize GvHD and GvL in allogeneic stem cell transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,867,908June 1, 2020May 31, 2026WALLER, EDMUND Kreporter.nih.gov
Molecular regulation of native hematopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,856,222February 15, 2016December 31, 2025CAMARGO, FERNANDOreporter.nih.gov
Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment Following Hematopoietic Stem Cell TransplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,855,157May 1, 2020April 30, 2026KELLER, MICHAEL DANIELreporter.nih.gov
Wnt signaling in hematopoietic developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,849,578January 1, 2017June 30, 2025WILLERT, KARL Hreporter.nih.gov
JAK-STAT Control of Zika Virus-Induced Fetal InjuryNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,840,817July 1, 2019June 30, 2025ADAMS WALDORF, KRISTINA M.reporter.nih.gov
Mechanisms of HIV-associated epithelialintestinal stem cell (ISC) dysfunctionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,811,833July 1, 2020June 30, 2025KWON, DOUGLASreporter.nih.gov
Cardiovascular reserve capacity in survivors of hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,785,889February 1, 2020January 31, 2026ARMENIAN, SAROreporter.nih.gov
Common Stem Cell of Origin for Junctional and Gastric AdenocarcinomaNIHNational Cancer Institute2022 to 2024$2,754,572September 15, 2022August 31, 2027MCKEON, FRANK D.reporter.nih.gov
Clinical and Molecular Heterogeneity in the Myelodysplastic SyndromesNIHNational Cancer Institute2021 to 2024$2,742,067April 1, 2020March 31, 2025PARK, CHRISTOPHER Yreporter.nih.gov
Development of FAST-DOSE assay system for the rapid assessment of acute radiation exposure, individual radiosensitivity and injury in victims for a large-scale radiological incidentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,738,709February 1, 2020January 31, 2026TURNER, HELEN Creporter.nih.gov
Conformal Total Body and Marrow Irradiation for LeukemiaNIHNational Cancer Institute2021 to 2024$2,727,228September 13, 2011December 31, 2025HUI, SUSANTA Kreporter.nih.gov
Epigenetic Profiling of circulating cell-free DNA for the Monitoring of Graft-Versus-Host Disease after Hematopoietic Cell TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,694,538January 13, 2020December 31, 2025DE VLAMINCK, IWIJNreporter.nih.gov
In vivo CRISPR engineering of B cells to produce anti-HIV broadly neutralizing antibodies using novel nanoparticlesNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,680,549June 8, 2022April 1, 2025ADAIR, JENNIFER EILEENreporter.nih.gov
How the 3D Architecture of the Brain Shapes Cancer Cell Fate DecisionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,670,000September 30, 2021August 31, 2026FILBIN, MARIELLA GRUBERreporter.nih.gov
Transcriptional Control During ErythropoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,660,464September 16, 2013October 31, 2025RANISH, JEFFREY Areporter.nih.gov
Genomics of bone and body composition traits in childrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,651,635August 7, 2020June 30, 2026ZEMEL, BABETTE Sreporter.nih.gov
Comparative Genomics of Precursor Diversity and FunctionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,631,720April 1, 2021February 28, 2026HAYDAR, TARIK Freporter.nih.gov
An Integrated In Vitro 3D Model of Human Bone Marrow and Peripheral InfectionNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,620,380September 15, 2021May 31, 2026GEORGE, STEVEN CARLreporter.nih.gov
Rectifying splicing mutations in blood disorders by gene editingNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,584,045December 20, 2019November 30, 2023BAUER, DANIEL EVANreporter.nih.gov
Targeted genetic engineering of B cells to induce protective antibody responses to viral pathogensNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,577,835July 5, 2022June 30, 2027ADAIR, JENNIFER EILEENreporter.nih.gov
The Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,563,053August 1, 2020July 31, 2025HUARD, JOHNNYreporter.nih.gov
Phase1/2a Clinical Trial of RPESC-derived RPE Transplantation as Therapy for Non-exudative Age-related Macular DegenerationNIHNational Eye Institute2021 to 2024$2,549,156September 30, 2020September 29, 2025STERN, JEFFREY Hreporter.nih.gov
Tissue chips for precision treatment of catecholaminergic polymorphic ventricular tachycardiaNIHNational Center for Advancing Translational Sciences2022 to 2024$2,546,193September 1, 2020July 31, 2025PU, WILLIAM TSWENCHINGreporter.nih.gov
The Molecular Regulation of Horizontal Basal Cell Activation in the Olfactory EpitheliumNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,546,159February 7, 2020January 31, 2026SCHWOB, JAMES E.reporter.nih.gov
Methamphetamine Effect on HIV PersistenceNIHNational Institute on Drug Abuse2021 to 2024$2,535,677July 1, 2020May 31, 2025KAUL, MARCUSreporter.nih.gov
Randomized study of low versus moderate dose busulfan in transplant for severe combined immunodeficiencyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,529,105August 24, 2017July 31, 2024WAYNE, ALAN S.reporter.nih.gov
Modeling, pathogenesis and treatment of idiopathic pulmonary fibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,527,128September 20, 2016May 31, 2025SNOECK, HANS-WILLEM Ereporter.nih.gov
The Genetic Architecture of Human Facial MorphologyNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,521,882July 14, 2017February 28, 2026WEINBERG, SETH Mreporter.nih.gov
Targeting the Metabolic Regulator SIRT5 in Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2024$2,518,197July 1, 2020June 30, 2025DEININGER, MICHAEL W.reporter.nih.gov
Editing Alveolar Progenitor Cells for Correction of Monogenic DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,504,499September 23, 2016May 31, 2025WHITSETT, JEFFREY Areporter.nih.gov
Fine-scale Spatiotemporal Mapping of Cellular Regulatory Networks Directing Heart DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,499,248August 1, 2020July 31, 2025CHI, NEIL Creporter.nih.gov
Using a SMART Design to Optimize PTSD Symptom Management Strategies Among Cancer SurvivorsNIHNational Cancer Institute2021 to 2024$2,482,100December 1, 2019November 30, 2025SMITH, SOPHIA K.reporter.nih.gov
Epigenetics and 3D Structure of miR-10b/HoxD Locus in the Brain and Malignant GliomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,479,682September 15, 2020July 31, 2025KRICHEVSKY, ANNA M.reporter.nih.gov
Characterization of Neural Stem Cells in Adult BrainNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,454,507April 1, 1990March 31, 2026ALVAREZ-BUYLLA, ARTUROreporter.nih.gov
Emergency Myelopoiesis Pathways in the Control of Blood ProductionNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,450,418April 1, 2017March 31, 2025PASSEGUE, EMMANUELLEreporter.nih.gov
Machine learning with immunogenetics for the prediction of hematopoietic cell transplant outcomesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,438,515January 5, 2021December 31, 2025HSU, KATHARINE Creporter.nih.gov
A Gata456 Pipeline of DiscoveryNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,432,169January 10, 2017December 31, 2023EVANS, TODD Rreporter.nih.gov
Stem cells for therapeutics discovery in genetic blood disordersNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,429,809September 23, 2016May 31, 2025DALEY, GEORGE Qreporter.nih.gov
The role of mitochondria in hematopoietic stem cell self-renewalNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,417,109January 1, 2021December 31, 2024FILIPPI, MARIE-DOMINIQUEreporter.nih.gov
Role of O-GlcNAcome on Breast Cancer Initiating CellsNIHNational Cancer Institute2021 to 2024$2,414,370March 1, 2020February 28, 2025REGINATO, MAURICIO J.reporter.nih.gov
Mathematical ecology models of host-microbiota interaction in auto microbiota transplants (auto-FMT)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,414,163February 1, 2019January 31, 2024XAVIER, JOAOreporter.nih.gov
Epithelial stem/progenitor cells as repair agents in diffuse alveolar damageNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,388,592September 21, 2016May 31, 2025CHAPMAN, HAROLD Areporter.nih.gov
Regulation of Ribosome Biogenesis in Hematopoietic Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,385,337September 18, 2020August 31, 2025TONG, WEIreporter.nih.gov
The 4D nucleome of muscle regeneration in ischemia-induced tissue damage and repairNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,377,116September 20, 2020August 31, 2025DIAO, YARUIreporter.nih.gov
Engineering Clinical Trials on a Chip for Dystrophin-Deficient Muscular DystrophyNIHNational Center for Advancing Translational Sciences2022 to 2024$2,376,851September 1, 2020July 31, 2026KIM, DEOK-HOreporter.nih.gov
Multipotent ABCB5-positive cell therapeutics for corneal diseaseNIHNational Eye Institute2021 to 2022$2,352,662April 1, 2018January 31, 2024FRANK, NATASHA Yreporter.nih.gov
Vsx2 Dependent Regulation of Retinal Progenitor Cell PropertiesNIHNational Eye Institute2021 to 2024$2,351,133August 1, 2003July 31, 2025LEVINE, EDWARD Mreporter.nih.gov
Progesterone Receptor (PR) Signaling Cross Talk Drives ER+ Breast CancerNIHNational Cancer Institute2021 to 2024$2,348,652February 13, 2020July 31, 2025LANGE, CAROL Areporter.nih.gov
Safety and Efficacy of Human Clinical Trials Using Kidney-on-a-Chip Microphysiological SystemsNIHNational Center for Advancing Translational Sciences2022 to 2024$2,334,876July 15, 2020June 30, 2026FREEDMAN, BENJAMIN SOLOMONreporter.nih.gov
Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,333,316September 15, 2016May 31, 2025ZHANG, JIANYIreporter.nih.gov
Novel Intervention Approaches to Alleviate Allogeneic Transplant-Related Morbidity and MortalityNIHNational Cancer Institute2021 to 2024$2,315,110September 3, 2018January 31, 2026SORROR, MOHAMEDreporter.nih.gov
A vascularized patient-derived iPSC liver acinus microphysiology system as an innovative precision medicine platform for optimizing clinical trial design for nonalcoholic fatty liver diseaseNIHNational Center for Advancing Translational Sciences2022 to 2024$2,306,928July 15, 2020June 30, 2026TAYLOR, D. LANSINGreporter.nih.gov
T cell invasion of the stem cell compartment during immune-mediated GI damageNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,299,846January 1, 2021December 31, 2025HANASH, ALAN Mreporter.nih.gov
Transcriptional Regulation of Lung Alveolar RegenerationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,270,370February 1, 2021December 31, 2024MORRISEY, EDWARD Ereporter.nih.gov
Mechanisms of oxysterol-induced oligodendrogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,255,433December 15, 2019November 30, 2024BENNER, ERIC Jreporter.nih.gov
Tympanic membrane progenitor cells in homeostasis in injuryNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,250,702April 25, 2020March 31, 2026TWARD, AARONreporter.nih.gov
Development of ASH1L inhibitors for acute leukemiaNIHNational Cancer Institute2021 to 2024$2,243,021December 1, 2019November 30, 2025GREMBECKA, JOLANTAreporter.nih.gov
PCTC Administrative Coordinating CenterNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,233,284September 20, 2016May 31, 2025TERRIN, MICHAEL Lreporter.nih.gov
Intraoperative bioprinting of composite tissues with zonal stratification for craniomaxillofacial reconstructionNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,227,502January 1, 2020December 31, 2025OZBOLAT, IBRAHIMreporter.nih.gov
Stem Cells and AgingNIHNational Institute of General Medical Sciences2021$2,226,780July 1, 2017June 30, 2024QUESENBERRY, PETER J.reporter.nih.gov
Multiplex base/prime editors for in vivo selection of modified HSPCs in hemoglobinopathyNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,218,334January 17, 2017December 31, 2025KIEM, HANS-PETERreporter.nih.gov
AML mutation-guided drugging of DNA repairNIHNational Cancer Institute2021 to 2024$2,200,960March 1, 2020January 31, 2026SKORSKI, TOMASZreporter.nih.gov
A microphysiologic multicellular organ-on-chip to inform clinical trials in FTD/ALSNIHNational Center for Advancing Translational Sciences2022 to 2024$2,198,065July 1, 2020November 30, 2025SVENDSEN, CLIVE NIELSreporter.nih.gov
Targeting an RNA Binding Protein Network in Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2024$2,173,391June 1, 2020May 31, 2025ABDEL-WAHAB, OMARreporter.nih.gov
Biological Comparisons Among Three Derivative Models of Glioma Patient Cancers Under Microenvironmental StressNIHNational Cancer Institute2021 to 2022$2,160,078September 17, 2018August 31, 2024WILLEY, CHRISTOPHER Dreporter.nih.gov
Therapeutic Targeting of Casein Kinase-1-delta in Primary and Metastatic Breast CancerNIHNational Cancer Institute2021 to 2023$2,159,273June 4, 2018November 30, 2023DUCKETT, DEREK RONALDreporter.nih.gov
Targeting plasma membrane spatial dynamics to suppress aberrant Wnt signalingNIHNational Cancer Institute2021 to 2024$2,143,591September 3, 2020May 31, 2026CHAPKIN, ROBERT STEPHENreporter.nih.gov
Manganese exposure susceptibility as a modifier of excitotoxicity in Alzheimer's DiseaseNIHNational Institute of Environmental Health Sciences2021 to 2024$2,124,884February 1, 2020October 31, 2025HARRISON, FIONA EDITHreporter.nih.gov
Human CDX2 Cells and Cardiac RepairNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,116,925July 21, 2020May 31, 2025CHAUDHRY, HINA Wreporter.nih.gov
Altered Hippocampal Neurogenesis and Cognition via Maneb-mediated Changes in the Thiol Redox Proteome.NIHNational Institute of Environmental Health Sciences2021 to 2023$2,104,664March 1, 2017February 28, 2026ROEDE, JAMES Rreporter.nih.gov
Targeting cancer stem cells in JAK2V617F induced neoplasmNIHNational Cancer Institute2021 to 2024$2,096,959February 15, 2020January 31, 2025LI, SHAOGUANGreporter.nih.gov
Ex vivo analysis of human brain tumor cells in a microvascular niche modelNIHNational Cancer Institute2021 to 2024$2,082,785February 4, 2020January 31, 2025FAN, RONGreporter.nih.gov
Targeting the Circadian Rhythm in Glioblastoma Stem Cells (R01CA238662)NIHNational Cancer Institute2021 to 2024$2,081,567July 1, 2021November 30, 2024RICH, JEREMY Nreporter.nih.gov
Function of RUNX1 in diverse Down syndrome tissuesNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,081,565September 1, 2023August 31, 2024ALLEN, MARY Areporter.nih.gov
Interplay between AMPK and Hippo Signaling Regulates Ocular Antiviral Response to Zika virus infectionNIHNational Eye Institute2021 to 2024$2,079,783January 1, 2021December 31, 2025ARUMUGASWAMI, VAITHILINGARAJAreporter.nih.gov
Cellular Reservoirs of HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,070,157September 23, 2019August 31, 2025COLLINS, KATHLEEN L.reporter.nih.gov
Mechanisms regulating functional heterogeneity of subcutaneous adipose tissues in womenNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,068,261July 8, 2019April 30, 2025FRIED, SUSAN Kreporter.nih.gov
Mechanistic Understanding for the Role of Lin28b in Pancreatic Cancer ProgressionNIHNational Cancer Institute2021 to 2023$2,060,694February 19, 2019January 31, 2024MOSTOSLAVSKY, RAULreporter.nih.gov
Treating Kidney Injury by Modulating Heat Shock Proteins Using Soundwaves Combined with Mesenchymal Stem Cells and Their Extracellular VesiclesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,048,853August 30, 2021July 31, 2025THAKOR, AVNESH SINHreporter.nih.gov
Investigating epigenetic mechanisms in Down syndrome using human cellular modelsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$2,034,753April 5, 2023March 31, 2026BARRETT, LINDY ELISEreporter.nih.gov
Neurobehavioral, cognitive, and mechanistic effects of intranasally administered neural stem cells and environmental enrichment after cortical impact injury in ratsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,032,869September 1, 2021August 31, 2025KLINE, ANTHONY E.reporter.nih.gov
Targeted Small Molecule Inhibitors for Inv(16) LeukemiaNIHNational Cancer Institute2021 to 2023$2,012,862December 1, 2018November 30, 2024BUSHWELLER, JOHN HACKETTreporter.nih.gov
Chromatin Organization Regulates OsteogenesisNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,010,351January 6, 2020December 31, 2024STEIN, GARY S.reporter.nih.gov
Exosome educated monocytes for acute radiation syndromeNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,007,828August 1, 2021July 31, 2025CAPITINI, CHRISTIANreporter.nih.gov
Matching panels of in vivo and in vitro model system of pediatric brain tumorsNIHNational Cancer Institute2021 to 2024$2,001,657March 3, 2020February 28, 2026LI, XIAONANreporter.nih.gov
TOPIC 414 : SYNTHETIC BIOLOGY GENE CIRCUITS FOR CANCER THERAPYNIHNational Cancer Institute2021$1,999,993August 1, 2021July 31, 2023LEE, GARYreporter.nih.gov
Phase 1/2a Clinical Study of Descartes-30 in Acute Respiratory Distress SyndromeNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,998,233May 1, 2021April 30, 2024STEWART, CHARLES ANDREWreporter.nih.gov
Vascular Remodeling in the Bone Marrow Leukemic Niche: A Therapeutic Target?NIHNational Cancer Institute2021 to 2024$1,996,349April 1, 2020March 31, 2026MARCUCCI, GUIDOreporter.nih.gov
In Vivo Proof of Concept and Target Identification Using Small Molecule Stimulators of Brown AdipogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,988,528July 1, 2020July 31, 2024BOSS, OLIVIERreporter.nih.gov
InflammaGut: a drug-screenable co-culture system using gut-associated lymphocytes and autologous primary human gut epithelium that reports inflammationNIHNational Center for Advancing Translational Sciences2022 to 2023$1,980,716May 1, 2022January 31, 2025THELIN, BILLreporter.nih.gov
Modeling the Glioblastoma Microenvironment to Uncover Progression Mechanisms and Therapeutic TargetsNIHNational Cancer Institute2021 to 2024$1,980,275May 1, 2020April 30, 2026BRAT, DANIEL Jreporter.nih.gov
Delirium in Children Undergoing Hematopoietic Stem Cell TransplantsNIHNational Cancer Institute2021 to 2024$1,975,976September 1, 2020May 31, 2026TRAUBE, CHANIreporter.nih.gov
Gastrin Regulation of Gastric Antral Stem and Corpus Progenitor CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,975,882September 23, 2021August 31, 2025WANG, TIMOTHY CRAGINreporter.nih.gov
Combined bioprinting with stem cell technology to regenerate skin burn woundsNIHNational Institute of General Medical Sciences2021 to 2024$1,972,718August 1, 2021May 31, 2026SQUARIZE, CRISTIANEreporter.nih.gov
Interplay between PDGFRA, oxygen-regulated translation and KSHV in Kaposi's sarcomagenesisNIHNational Cancer Institute2021 to 2024$1,972,648May 1, 2010February 28, 2026SHEMBADE, NOULA DATTUreporter.nih.gov
Engineered Neuroprotective Stem-Cell Exosomes for In Utero Spina Bifida TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,972,069September 30, 2020August 31, 2025FARMER, DIANA LEEreporter.nih.gov
Tumor matrix remodeling in anti-myeloma immunity and immunotherapyNIHNational Cancer Institute2021 to 2024$1,950,659July 1, 2020December 31, 2024ASIMAKOPOULOS, FOTIOSreporter.nih.gov
Discovery of small molecule regulators of atrial cardiomyocyte action potential duration to restore normal cardiac rhythm in atrial fibrillationNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,950,000June 10, 2021August 31, 2025COLAS, ALEXANDRE ROMAINreporter.nih.gov
DOT1L, reconstitution of plasmacytoid dendritic cells and alloimmunityNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,948,900November 23, 2021March 31, 2026ZHANG, YIreporter.nih.gov
Investigating the effects of aerobic and resistance training in vivo on skeletal muscle metabolism in vitro in primary human muscle cells (MoTrMyo)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,938,650August 1, 2019May 31, 2026SPARKS, LAUREN MARIEreporter.nih.gov
Development of a DCLK1 siRNA Nanoparticle as Targeted Therapy to Treat Pancreatic CancerNIHNational Cancer Institute2021 to 2022$1,935,472August 22, 2018July 31, 2024DE OLIVEIRA, ELISEU O.reporter.nih.gov
Maternal programming of the stem cell-basophil axis for asthmaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,932,227July 20, 2020June 30, 2025GORSKA, MAGDALENA MARIAreporter.nih.gov
Mechanisms Controlling Expansion and Lineage Specification of Airway Progenitors in Development and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,919,136January 1, 2017June 30, 2023CARDOSO, WELLINGTON V.reporter.nih.gov
Mechanisms governing metastatic dormancy and reactivationNIHNational Cancer Institute2021 to 2022$1,915,493August 1, 2016July 31, 2023GIANCOTTI, FILIPPO Greporter.nih.gov
Development of a Bio-tissue Oxygenation Nanophosphor Enabled Sensing (BONES) system for Quantifying Hypoxia in Bone MarrowNIHNational Institute of General Medical Sciences2021 to 2023$1,915,320June 1, 2021February 28, 2025YUN, WENBINGreporter.nih.gov
Defining malignant hematopoiesis via single-cell multi-omicsNIHOffice of the Director, National Institutes of Health2021 to 2024$1,910,784September 15, 2020August 31, 2025NAM, SEUNG HAreporter.nih.gov
Single-cell proteomic identification of novel markers of senescenceNIHNational Cancer Institute2023 to 2024$1,902,334September 22, 2021August 31, 2025DOU, ZHIXUNreporter.nih.gov
Brain Development in Down Syndrome during Fetal and Early Postnatal AgesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024$1,896,457September 18, 2024August 31, 2027TAKAHASHI (OKI), EMIreporter.nih.gov
Determining lineage decisions and gene regulatory networks governing the generation of key progenitor cell types during early human brain developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,890,725April 7, 2020March 31, 2025RAMANATHAN, SHARADreporter.nih.gov
Home-based Autologous Hematopoietic Stem Cell Transplantation to Improve Outcomes and Decrease CostsNIHNational Institute on Aging2021 to 2024$1,889,750June 1, 2020June 1, 2024SUNG, ANTHONYreporter.nih.gov
A 2D Intestinal Crypt Platform for Compound ScreensNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$1,888,698July 1, 2021July 31, 2025SIMS, CHRISTOPHER ELDRIDGEreporter.nih.gov
A Phase II Controlled Trial of Allogeneic Mesenchymal Stem Cells for the Treatment of Refractory LupusNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,880,006March 19, 2018July 31, 2024GILKESON, GARY Sreporter.nih.gov
Targeting of Mitochondrial Lon Protease as a Novel Therapy for GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,872,035September 1, 2020May 31, 2026BOTA, DANIELA ANNENELIEreporter.nih.gov
Defining genetic and metabolic requirements of aggressive breast cancerNIHNational Cancer Institute2021 to 2024$1,861,232April 1, 2020March 31, 2026WALTZ, SUSAN Ereporter.nih.gov
Prenatal metal mixtures and neurodevelopment: Role of placental extracellular microRNAsNIHNational Institute of Environmental Health Sciences2021 to 2023$1,860,956June 1, 2019May 31, 2024WRIGHT, ROSALIND Jreporter.nih.gov
Transcriptional and epigenetic basis of lung epithelial cell fateNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,860,726July 1, 2020December 31, 2023CHEN, JICHAOreporter.nih.gov
Targeting dysregulated transcriptome as therapy for post-myeloproliferative neoplasm (MPN) sAMLNIHNational Cancer Institute2021 to 2024$1,860,616April 13, 2020March 31, 2025BHALLA, KAPILreporter.nih.gov
NF-kB Regulation of the Muscle Microenvironment in Cancer CachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,849,772February 26, 2020June 30, 2025GUTTRIDGE, DENIS Creporter.nih.gov
Regulators of Development and Quiescence in the Human Muscle Stem Cell LineageNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,846,023September 25, 2019August 31, 2025POURQUIE, OLIVIERreporter.nih.gov
Multimodal approach investigating the immunomodulatory effect ofneural stem cells in stroke recoveryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,840,475August 1, 2008January 31, 2026STEINBERG, GARY Kreporter.nih.gov
Patient-derived Models of Synaptic Pruning in SchizophreniaNIHNational Institute of Mental Health2021 to 2023$1,832,595July 19, 2019April 30, 2025PERLIS, ROY H.reporter.nih.gov
Targeting Clonal Hematopoiesis of Indeterminate Potential using Human GeneticsNIHOffice of the Director, National Institutes of Health2021 to 2024$1,830,957September 15, 2020August 31, 2025BICK, ALEXANDERreporter.nih.gov
Relationships between parity, breastfeeding and ER- breast cancer in African American women: Elucidating the biologic underpinnings at the molecular and cellular level.NIHNational Cancer Institute2021 to 2023$1,829,705December 4, 2018November 30, 2024AMBROSONE, CHRISTINE B.reporter.nih.gov
Targeting breast cancer stem cellsNIHNational Cancer Institute2021 to 2022$1,826,944February 1, 2016January 31, 2024WICHA, MAX S.reporter.nih.gov
Gene Networks promoting adipocyte cell differentiation and functionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,817,690April 1, 2020March 31, 2025SEALE, PATRICKreporter.nih.gov
Hippo Signaling Effector and PlacentationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,816,512April 1, 2020March 31, 2026PAUL, SOUMENreporter.nih.gov
Investigating tau and ApoE4-mediated alterations in oligodendrocyte progenitor cellsNIHNational Institute on Aging2022 to 2024$1,813,828June 1, 2022February 28, 2028COOK, CASEY Nreporter.nih.gov
Preclinical development of ONCT-505, an Androgen Receptor Antagonist and Degrader, as New Potential Therapeutic for Kennedy's DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,810,779March 15, 2023February 28, 2025KRISHNAN, RAJESHreporter.nih.gov
Targeting alternative splicing for TCR discovery in small cell carcinomasNIHNational Cancer Institute2021 to 2022$1,809,996September 21, 2018August 31, 2024WITTE, OWEN N.reporter.nih.gov
Analysis of E-selectin Ligands of Human Acute Leukemia Cells and their Biology in LeukemogenesisNIHNational Cancer Institute2021 to 2023$1,799,538July 17, 2019June 30, 2025SACKSTEIN, ROBERTreporter.nih.gov
Systematic dissection of gut cellular circuits [at single cell resolution]NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$1,795,970August 1, 2017May 31, 2023XAVIER, RAMNIK Jreporter.nih.gov
Proteomic Profiling of Patent Foramen Ovale Related Neurovascular InjuryNIHNational Institute of Neurological Disorders and Stroke2024$1,795,134July 1, 2010June 30, 2027NING, MINGMINGreporter.nih.gov
The unique roles of the GTP-binding/protein crosslinking enzyme transglutaminase-2 and signaling partners in aggressive cancersNIHNational Cancer Institute2021 to 2024$1,783,848December 4, 2015April 30, 2026CERIONE, RICHARD A.reporter.nih.gov
"Clinical Trials" on a Premature Vascular Aging-on-a-Chip ModelNIHNational Center for Advancing Translational Sciences2022 to 2024$1,780,604August 1, 2020July 31, 2025ZHANG, Y. SHRIKEreporter.nih.gov
PPM1D in Clonal Hematopoiesis and MalignanciesNIHNational Cancer Institute2021 to 2023$1,774,910July 1, 2019June 30, 2025GOODELL, MARGARET A.reporter.nih.gov
Mechanisms Mediating Osseointegration of 3D Printed Titanium ConstructsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,766,718January 7, 2019December 31, 2024BOYAN, BARBARA D.reporter.nih.gov
Understanding and Using Variation in Source Materials for MSC FabricationNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,762,373August 14, 2019April 30, 2025MUSCHLER, GEORGE Freporter.nih.gov
Phase I/II clinical trial of HDAC inhibition for GVHD prevention in children, adolescents, and young adultsNIHNational Cancer Institute2021 to 2024$1,755,671June 1, 2020May 31, 2026CHOI, SUNG WONreporter.nih.gov
Translational Control of Leukemia Stem Cells - Resubmission - 1NIHNational Cancer Institute2021 to 2024$1,751,741July 1, 2020June 30, 2025PARK, CHRISTOPHER Yreporter.nih.gov
NRSA Training CoreNIHNational Center for Advancing Translational Sciences2021 to 2024$1,743,177August 13, 2015March 31, 2026KOTTON, DARRELL N.reporter.nih.gov
Using hiPSCs to develop physiologically-relevant outer retina tissue mimeticsNIHNational Eye Institute2022 to 2024$1,738,353September 30, 2022August 31, 2025SINGH, RUCHIRAreporter.nih.gov
Optimal Tissue Engineering Approach for Treating Injured Vocal FoldsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2023$1,735,877December 1, 2018November 30, 2025FREYTES, DONALD Oreporter.nih.gov
DNA Methylation at N6-Adenine in Placental Trophoblast DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$1,734,519August 1, 2020April 30, 2026JIANG, ZONGLIANGreporter.nih.gov
Role of an Integrator-EGR axis in the regulation of myeloid enhancersNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,732,815February 1, 2019November 30, 2024GARDINI, ALESSANDROreporter.nih.gov
Clickable Microgel Scaffolds for MSC Expansion and DeliveryNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,727,811March 5, 2019February 28, 2025ANSETH, KRISTI S.reporter.nih.gov
Mechanisms of actions(s) of simvastatin in uterine leiomyomaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,719,127August 1, 2018July 31, 2025BORAHAY, MOSTAFA A.reporter.nih.gov
Imaging and Blood Biomarkers to Predict Graft Failure after HSCTNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,715,532September 25, 2019July 31, 2025WILLIAMS, KIRSTENreporter.nih.gov
Investigating the direct reprogramming of fibroblasts into skeletal muscle progenitorsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,713,632August 15, 2020May 31, 2025HOCHEDLINGER, KONRADreporter.nih.gov
Regulation and function of hematopoietic stem cell nichesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,682,486March 1, 2000December 31, 2024GRITSMAN, KIRAreporter.nih.gov
Restoration of myocardial reparative function of diabetic progenitor cells by epigenetic modulationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,680,897December 10, 2019November 30, 2025KISHORE, RAJreporter.nih.gov
Efficient and scalable microfluidic gene delivery to hematopoietic stem cells to treat blood diseasesNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,680,456August 15, 2019June 30, 2024HAN, SEWOONreporter.nih.gov
Molecular and Epigenetic Control of Wnt/b-catenin-mediated oncogenesis by KDM4BNIHNational Cancer Institute2021 to 2024$1,675,571February 1, 2020January 31, 2025WANG, CUN-YUreporter.nih.gov
In vitro modeling of blood brain barrier dysfunction on a chip to elucidate the pathogenesis of cerebral malariaNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,675,237September 15, 2021August 31, 2023GOLIGHTLY, LINNIEreporter.nih.gov
MPN-inducing mutations as biomarkers of synthetic lethalityNIHNational Cancer Institute2021 to 2024$1,674,115June 1, 2020May 31, 2026SKORSKI, TOMASZreporter.nih.gov
The function and underlying mechanism of TET1 in myelodysplastic syndromesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,663,013March 10, 2020December 31, 2023CHEN, JIANJUNreporter.nih.gov
MUC1-C is a Target for Reversing Immune Evasion and Resistance to ImmunotherapiesNIHNational Cancer Institute2021 to 2022$1,659,300September 20, 2018August 31, 2024KUFE, DONALD W.reporter.nih.gov
Resetting immune homeostasis: a non-invasive approach towards HIV eradicationNIHNational Institute of Allergy and Infectious Diseases2021$1,648,370August 9, 2017July 31, 2025SEKALY, RAFICK PIERREreporter.nih.gov
AMYLOIDOGENIC INDUCTION OF CELLULAR SENESCENCE IN ALZHEIMER'S DISEASENIHNational Institute on Aging2021 to 2024$1,645,988August 1, 2020July 31, 2025MIRANKER, ANDREW D.reporter.nih.gov
Wnt5a, a New Diabetic Corneal Marker Related to Wound HealingNIHNational Eye Institute2021 to 2024$1,644,857September 30, 2020August 31, 2025LJUBIMOV, ALEXANDER Vreporter.nih.gov
Biomechanical Activation of Yap Induces Hematopoietic Stem Cell ProductionNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,632,318April 1, 2020March 31, 2026NORTH, TRISTA E.reporter.nih.gov
Imaging of Hematologic and Oncologic DisordersNIHNational Cancer Institute2021 to 2022$1,625,586May 1, 2016April 30, 2024ROSS, BRIAN D.reporter.nih.gov
A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)NIHNational Cancer Institute2022 to 2024$1,622,400June 10, 2022May 31, 2027CHANG, JENNY C-Nreporter.nih.gov
Development of a microphysiologic system to assay the interaction of the human colonic epithelium on Clostridium difficileNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,620,228March 1, 2020December 31, 2024ALLBRITTON, NANCY L.reporter.nih.gov
Developing next generation synthetic nucleic acid analogous for sickle cell disease gene editingNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,610,000December 15, 2019November 30, 2025BAHAL, RAMANreporter.nih.gov
Mechanisms for Impaired Adaptation to Aerobic Exercise with Metabolic DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,607,583September 15, 2020July 14, 2024LESSARD, SARAHreporter.nih.gov
The Role of RHOA in Diffuse Gastric CancerNIHNational Cancer Institute2021 to 2022$1,607,160June 8, 2018December 31, 2022WANG, TIMOTHY CRAGINreporter.nih.gov
Inflammatory mechanisms responsible for the development of multiple organ dysfunction in pediatric patients following allogeneic blood and marrow transplantation (BMT).NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,598,857February 1, 2020January 31, 2026COOKE, KENNETH Rreporter.nih.gov
New sterol-binding targets and optimized EBP inhibitors for promoting remyelinationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,598,057May 1, 2020January 31, 2025ADAMS, DREW JAMESreporter.nih.gov
Lineage specifiers governing pancreatic cancer growth and molecular subtypeNIHNational Cancer Institute2021 to 2024$1,576,922June 1, 2020May 31, 2026SNYDER, ERIC LEEreporter.nih.gov
Enterovirus Infection of Polarized Intestinal CellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,575,846July 1, 2021May 31, 2026COYNE, CAROLYN Breporter.nih.gov
Nanotechnology for targeted therapy and fundamental understanding oftherapeutic resistance in triple negative breast cancerNIHNational Cancer Institute2021 to 2024$1,574,340April 1, 2020March 31, 2026HE, XIAOMINGreporter.nih.gov
Cone subtype specification in human retinas and organoidsNIHNational Eye Institute2021 to 2023$1,566,838January 1, 2020December 31, 2024JOHNSTON, ROBERT JOHNreporter.nih.gov
Epigenetic Regulation of Bone Regeneration in Inflammatory DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,566,325July 8, 2019June 30, 2025SHEN, JIEreporter.nih.gov
BCL11B activation as an approach for enhancing the efficacy of immunotherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,566,114February 11, 2021July 1, 2024PAREKH, CHINTANreporter.nih.gov
Human brain multi-omics to decipher major depression pathophysiologyNIHNational Institute of Mental Health2023 to 2024$1,565,284September 1, 2023June 30, 2028BOLDRINI, MAURAreporter.nih.gov
Oncogenic tyrosine kinases inhibitors abrogate DNA repair and sensitive leukemias to PARP inhibitorsNIHNational Cancer Institute2021 to 2024$1,562,631April 1, 2020March 31, 2026SKORSKI, TOMASZreporter.nih.gov
Role of ER Stress and Fatty Acid Metabolism in Glioma Stem CellsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,562,282September 15, 2020July 31, 2026BADR, CHRISTIAN ELIASreporter.nih.gov
Atypical TDP43 isoforrms driving neurodegeneration in FTD/ALSNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,560,000December 1, 2019November 30, 2025BARMADA, SAMIreporter.nih.gov
Heat Shock Transcription Factor 1 Specifically Regulates AML Stem Cell Self-RenewalNIHNational Cancer Institute2021 to 2024$1,558,730December 15, 2019May 31, 2025ZHAO, CHENreporter.nih.gov
A NOVEL LINEAGE SPECIFIC METASTASIS PATHWAY IN LUNG CANCERNIHNational Cancer Institute2021 to 2024$1,555,447December 1, 2012November 30, 2025NGUYEN, DON Xreporter.nih.gov
Targeting DNA repair to eradicate TKi-refractory/resistant CML and Ph+ALLNIHNational Cancer Institute2021 to 2024$1,543,188August 12, 2014February 28, 2026SKORSKI, TOMASZreporter.nih.gov
Role of VGLL1 in human placental development and trophoblast specificationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,539,133February 1, 2019January 31, 2025SONCIN, FRANCESCAreporter.nih.gov
Mechanisms of Posterior Heart Field DevelopmentNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,535,814August 1, 2020July 31, 2024CHI, NEIL Creporter.nih.gov
Ex vivo hematopoietic stem cell growth mediated by the heat shock responseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,534,861March 1, 2020December 31, 2024SIGNER, ROBERT A.J.reporter.nih.gov
Molecular, Epigenetic and Genomic Approaches to Understand Mechanisms of Aging in the Human TestisNIHNational Institute on Aging2021 to 2024$1,525,000September 30, 2020May 31, 2025CAIRNS, BRADLEY R.reporter.nih.gov
Multiscale Models of Wound Cell Plasticity for RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,520,232September 1, 2018June 30, 2024NIE, QINGreporter.nih.gov
Sustained delivery of therapeutics to the visual system using genetically modified autologous mesenchymal stem cells to treat blinding diseasesNIHNational Eye Institute2021 to 2023$1,519,053May 1, 2019April 30, 2025WHITING, REBECCA EHreporter.nih.gov
Understanding the neurodevelopmental role and mechanism of histone demethylase JMJD3NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,506,714July 15, 2020April 30, 2025LIM, DANIEL Areporter.nih.gov
Assessment of Metabolites Among Asymptomatic Precursor and Malignant Monoclonal GammopathiesNIHNational Cancer Institute2021 to 2024$1,503,881March 1, 2021February 28, 2026GONSALVES, WILSONreporter.nih.gov
Development of Novel MNK Inhibitors for Treating GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,503,510September 1, 2019June 30, 2024PLATANIAS, LEONIDAS C.reporter.nih.gov
Novel Small Molecule Anti-Inflammatory Eye Drops for Ocular Graft Versus Host DiseaseNIHNational Eye Institute2021 to 2022$1,499,999February 1, 2021August 31, 2024DING, JINDONGreporter.nih.gov
Translating Intestinal Radioprotection by EGLN Inhibition to Improve Clinical Outcomes in Unresectable Pancreatic CancerNIHNational Cancer Institute2021 to 2023$1,496,161April 1, 2019March 31, 2024KOONG, ALBERTreporter.nih.gov
A RIPK2-Targeting Apoptosis-Inducing Small Molecule for the Treatment of GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,492,646June 1, 2019March 31, 2024LAIRSON, LUKE LEEreporter.nih.gov
Mechanisms of enhancer regulation in leukemiaNIHNational Cancer Institute2021 to 2023$1,487,277January 1, 2019December 31, 2023AIFANTIS, IANNISreporter.nih.gov
Predictive and systems modeling of exosome cargoNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,483,018January 1, 2019December 31, 2023DAVIS, MICHAEL Ereporter.nih.gov
Osteoclast modulatory biomaterials for skull regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,475,710August 1, 2020July 31, 2025LEE, JUSTINE CHIAreporter.nih.gov
Designing cell-instructive hydrogels to understand and exploit mechanobiologyNIHNational Institute of General Medical Sciences2021 to 2024$1,473,308September 1, 2020July 31, 2025CALIARI, STEVENreporter.nih.gov
"Establishing Pathways for Endothelial Support of Bone Formation with SLIT3"NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,465,497April 1, 2020February 28, 2025GREENBLATT, MATTHEW BLAKEreporter.nih.gov
Driver Genes for Engineered Rotator Cuff DevelopmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,459,537March 15, 2019August 31, 2025LITTLE, DIANNEreporter.nih.gov
Decoding innate immune signaling in normal and myelodysplastic hematopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,453,441January 10, 2017December 31, 2022STARCZYNOWSKI, DANIELreporter.nih.gov
Targeted Inhibition in LeukemiaNIHNational Cancer Institute2021 to 2023$1,448,596July 8, 2020June 30, 2025NASSAR, NICOLASreporter.nih.gov
Cell adhesion and cytoskeletal dynamics in the skinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,438,349December 1, 1980August 31, 2023FUCHS, ELAINEreporter.nih.gov
The Allogeneic Human Mesenchymal Stem Cell (MSCs) injection in Patients with Hypoplastic Left Heart Sydrome: A Phase IIb Clinical Trial (ELPIS)NIHNational Heart, Lung, and Blood Institute2021 to 2024$1,435,351September 15, 2020August 31, 2025LAI, DEJIANreporter.nih.gov
Human Acute Myeloid Leukemia Stem CellsNIHNational Cancer Institute2021 to 2024$1,433,586July 7, 2020June 30, 2025MAJETI, RAVINDRAreporter.nih.gov
Alzheimer's disease-replicated brain microphysiological system to model AD physiopathology and its influenceon gliovasculature and immune systemNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,423,803February 1, 2021January 31, 2026YUN, YEOHEUNGreporter.nih.gov
pathQTL: Integrative Multi-Omics Causal Inference of Molecular Mechanisms Leading to Neuropsychiatric IllnessNIHNational Institute of Mental Health2021 to 2023$1,412,584December 10, 2018November 30, 2023STEIN, JASON LOUISreporter.nih.gov
Understanding stem cell heterogeneity and niche function in intestinal regeneration after irradiationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,404,650September 1, 2023August 31, 2024WANG, TIMOTHY CRAGINreporter.nih.gov
Defining and targeting a novel pathway for central nervous system leptomeningeal metastasisNIHNational Cancer Institute2021 to 2024$1,400,663January 6, 2020December 31, 2025SIPKINS, DOROTHY Areporter.nih.gov
Maternal obesity and neonatal innate immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,397,637September 24, 2018August 31, 2025MESSAOUDI, ILHEMreporter.nih.gov
SON-mediated RNA splicing in glioblastomaNIHNational Cancer Institute2021 to 2024$1,396,874July 1, 2020June 30, 2025AHN, ERIN EUN-YOUNGreporter.nih.gov
Rejuvenating aged bone regeneration by innovative nanomaterials-mediated drug deliveryNIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,394,310July 1, 2020April 30, 2026SUN, HONGLIreporter.nih.gov
The aging stem cell nicheNIHNational Institute on Aging2021 to 2024$1,389,900September 30, 2020April 30, 2026HUBBARD, E. JANE ALBERTreporter.nih.gov
Vascular mural cells in the development of the blood brain barrierNIHNational Institute of Mental Health2023$1,388,925September 1, 2023August 31, 2026CROUCH, ELIZABETH ERINreporter.nih.gov
Defining the role of TCAB1 and its phase separation in telomerase assembly.NIHNational Institute of General Medical Sciences2021 to 2024$1,383,810September 1, 2021July 31, 2025SCHMIDT, JENS CHRISTOPHERreporter.nih.gov
Identifying Predictors of Poor Health-Related Quality-of-life among Pediatric Hematopoietic Stem Cell DonorsNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,383,204January 6, 2018December 31, 2024SWITZER, GALEN E.reporter.nih.gov
Distinct contributions of mesenchymal cell niches in the therapeutic potential of the hedgehog pathway in triple negative breast cancerNIHNational Institute of General Medical Sciences2021 to 2023$1,379,794August 1, 2020July 31, 2025DOMENECH, MARIBELLAreporter.nih.gov
NAD+ Pathway Signaling in Glioblastoma Tumor Growth and Therapy ResistanceNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,377,703July 1, 2019June 30, 2025KIM, ALBERT HONG-JAEreporter.nih.gov
Molecular targeting of erythroid progenitor cells in normal and disordered human erythropoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,375,136January 15, 2019December 31, 2023BLANC, LIONELreporter.nih.gov
Regenerative Lipid Mediators for the Management of Severe Burn WoundsNIHNational Institute of General Medical Sciences2021 to 2023$1,367,499April 20, 2020February 28, 2026HONG, SONGreporter.nih.gov
Sliding hydrogels for accelerating cartilage regenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,364,113September 1, 2019July 31, 2025YANG, FANreporter.nih.gov
The role and mechanism of METTL3/METTL14-mediated RNA modification in the pathogenesis and drug-resistance of AMLNIHNational Cancer Institute2021 to 2023$1,361,506February 1, 2019January 31, 2024CHEN, JIANJUNreporter.nih.gov
Developing a SMART scaffold for bladder augmentationNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$1,351,330August 9, 2019November 30, 2024AMEER, GUILLERMO ANTONIOreporter.nih.gov
Bayesian Methods for Complex Precision Biotherapy Trials in OncologyNIHNational Cancer Institute2021 to 2024$1,350,553September 15, 2021August 31, 2025THALL, PETER Freporter.nih.gov
A novel approach for treating diabetes using pulsed focused ultrasound and intra-arterial delivery of mesenchymal stem cell based therapies directly into the pancreasNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,349,935September 1, 2019May 31, 2024THAKOR, AVNESH SINHreporter.nih.gov
Cellular and functional impact of SAMD9L mutations on hematopoiesis and myelodysplasiaNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,346,250January 1, 2019December 31, 2024KLCO, JEFFERY Mreporter.nih.gov
Stem cell-based tissue engineering for myotendinous junction modeling and repairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,344,008April 1, 2020January 31, 2026SUZUKI, MASATOSHIreporter.nih.gov
The influence of common genetic variation on brain overgrowth pathwaysNIHNational Institute of Mental Health2021 to 2023$1,336,156August 1, 2019May 31, 2025STEIN, JASON LOUISreporter.nih.gov
Enhancement of stem cell regenerative properties by hydrogen sulfide: a novel wound dressing to augment stem cell therapiesNIHNational Institute of General Medical Sciences2021 to 2023$1,332,634September 15, 2020August 31, 2025TOLIVER-KINSKY, TRACY Ereporter.nih.gov
Regulatory Landscape of the Aging Human OvaryNIHNational Institute on Aging2021 to 2024$1,329,912September 30, 2020May 31, 2025WILLIAMS, ZEVreporter.nih.gov
Aging and dysfunction of progenitor niches: Role of Del-1NIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,326,269January 1, 2020December 31, 2025HAJISHENGALLIS, GEORGIOSreporter.nih.gov
Structure-based Bioengineering of Wnt Surrogates for Intestinal Stem Cell Biology and TherapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,323,906August 15, 2018June 30, 2024KUO, CALVIN Jreporter.nih.gov
Stem cells for craniofacial bone repair and regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2022$1,322,241June 30, 2021May 31, 2025HSU, WEIreporter.nih.gov
Endothelial progenitor cells and neurovascular injury in the aging brainNIHNational Institute on Aging2021 to 2023$1,321,673September 1, 2019August 1, 2023NATION, DANIEL Areporter.nih.gov
The role and regulation of Hippo pathway in sarcomagenesisNIHNational Cancer Institute2021 to 2023$1,314,226March 1, 2019February 29, 2024EISINGER, TZIPORA SARAH KARINreporter.nih.gov
A cutaneous gene therapy for cocaine abuse and alcohol co-abuseNIHNational Institute on Drug Abuse2021 to 2023$1,312,200September 30, 2019July 31, 2025XU, MINGreporter.nih.gov
Specialized cell cycles in early erythropoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,308,027September 15, 2019June 30, 2025SOCOLOVSKY, MERAVreporter.nih.gov
Identification of therapeutic targets for leukemia stem cells in AML-iPSC modelsNIHNational Cancer Institute2021 to 2022$1,306,690March 1, 2018February 28, 2023PAPAPETROU, EIRINIreporter.nih.gov
Zika Virus Capsid Protein Mediated Blockage of host microRNA machineryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,302,099May 1, 2019February 28, 2025ZHAO, ZHENreporter.nih.gov
Hypopituitarism: role of PROP1 and retinoic acid signaling in regulation of pituitary stem cell differentiationNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,296,374March 4, 2019February 29, 2024CAMPER, SALLY A.reporter.nih.gov
Obesity-induced mesenchymal stem cell senescenceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,283,174December 27, 2018November 30, 2024LERMAN, LILACH Oreporter.nih.gov
Tumor-Suppressive Functions and Molecular Regulation of LRIG1 in Prostate Cancer and CRPCNIHNational Cancer Institute2021 to 2023$1,283,103March 1, 2019August 31, 2024TANG, DEAN G.reporter.nih.gov
Targeting Drug-Resistant Cancer Stem Cell Niches of Gastrointestinal Stromal TumorNIHNational Cancer Institute2021 to 2023$1,276,977June 1, 2019May 31, 2024SICKLICK, JASON KEITHreporter.nih.gov
The Human Distal Airway Aging ProjectNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,276,622January 1, 2019December 31, 2023SHAYKHIEV, RENATreporter.nih.gov
Skeletal Muscle Stem Cells Derived from TeratomasNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,274,254May 1, 2019April 30, 2024KYBA, MICHAELreporter.nih.gov
Mesodermal Commitment of the Definitive Hematopoietic ProgramNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,268,334January 15, 2021April 30, 2025STURGEON, CHRISTOPHER MICHAELreporter.nih.gov
Redefining mesenchymal stem cells: using their cellular and molecular phenotypes to determine their regenerative and therapeutic propertiesNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,262,179September 1, 2019August 31, 2025KAIGLER, DARNELLreporter.nih.gov
Macrocyclic Peptidyl Inhibitors of NEMO-IKK InteractionNIHNational Cancer Institute2021 to 2023$1,247,018July 1, 2019June 30, 2026PEI, DEHUAreporter.nih.gov
Analysis of epithelial heterogeneity in prostate development and cancerNIHNational Cancer Institute2021 to 2023$1,242,555April 1, 2019August 31, 2024SHEN, MICHAEL M.reporter.nih.gov
Efficient Sendai virus mediated CRISPR/Cas9 gene editing to protect hematopoietic stem cells from HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,241,707June 11, 2018May 31, 2024AN, DONG SUNGreporter.nih.gov
The Peripheral Nervous System: A Window into Krabbe DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,234,701February 1, 2019January 31, 2025SIM, FRASER JAMESreporter.nih.gov
Single Cell Profiling To Define Biomarkers Of Photoreceptor Dysfunction After Gene Editing Within PSC-Derived OrganoidsNIHNational Eye Institute2021 to 2022$1,223,974September 5, 2018June 30, 2024SAHA, KRISHANUreporter.nih.gov
Defining the intestinal stem cell niche during organoid development into a functional human intestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,222,000September 1, 2014August 31, 2024HELMRATH, MICHAEL A.reporter.nih.gov
Progenitor cell based therapy to mitigate radiation induced gastro intestinal syndrome- supplementNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,220,595March 7, 2018February 29, 2024SAHA, SUBHRAJITreporter.nih.gov
Niche support of human intestinal stem cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,213,203September 1, 2014August 31, 2024SPENCE, JASONreporter.nih.gov
Progenitor Regulation Underlying Cortical Interneuron SpecificationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,212,394July 1, 2018March 31, 2024ROSS, MARGARET ELIZABETHreporter.nih.gov
Stromal cell therapy as a treatment against Gastrointestinal Acute Radiation Syndrome (GI-ARS)NIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,193,484March 9, 2018February 29, 2024GUHA, CHANDANreporter.nih.gov
Utilizing beige fat to improve muscle function after rotator cuff repairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,192,600September 1, 2018June 30, 2024FEELEY, BRIANreporter.nih.gov
Regulation of Human Epidermal Tumorigenesis by the mRNA Degradation PathwayNIHNational Cancer Institute2021 to 2023$1,183,479December 1, 2018November 30, 2024SEN, GEORGE Lreporter.nih.gov
Hematopoietic Stem and Progenitor Cell Dysfunction is an Underlying Mechanism of Injury-Inuced ImmunosuppressionNIHNational Institute of General Medical Sciences2021 to 2023$1,181,248September 5, 2019June 30, 2025TURNBULL, ISAIAH Rreporter.nih.gov
The role of Abelson interactor 1 (Abi-1) in hematopoietic stem cell self-renewal and malignant transformationNIHNational Cancer Institute2021 to 2023$1,172,540July 24, 2019June 30, 2025DUBIELECKA-SZCZERBA, PATRYCJA MARTAreporter.nih.gov
Targeting trained immunity and Th1/Th17 axis with combination adjuvantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,167,749July 26, 2021September 1, 2022KHADER, SHABAANA A.reporter.nih.gov
Pathobiological mechanisms of persistent post-COVID19 olfactory dysfunctionNIHNational Institute on Deafness and Other Communication Disorders2021 to 2022$1,164,667August 15, 2019June 30, 2024GOLDSTEIN, BRADLEY Jreporter.nih.gov
Electrical Stimulation of Human CPCsNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,162,500February 10, 2020February 28, 2026MAXWELL, JOSHUA THOMASreporter.nih.gov
Targeting Lipid Unsaturation in Ovarian Cancer Stem CellsNIHNational Cancer Institute2021 to 2022$1,158,147August 1, 2018July 31, 2024MATEI, DANIELA Ereporter.nih.gov
The impact of HIV driven T cell immune activation in angiogenic CD8 T cell function: the role of PAR1 signalingNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,157,094May 23, 2019February 28, 2025CATALFAMO, MARTA L.reporter.nih.gov
Revealing muscle stem cell heterogeneity in mice and humans through deep single-cell analysisNIHNational Institute on Aging2021 to 2022$1,150,610September 30, 2018May 31, 2024COSGROVE, BENJAMIN DAVIDreporter.nih.gov
Magnetic Steering and Longitudinal Visualization of Stem Cells for Trabecular Meshwork Therapy in GlaucomaNIHNational Eye Institute2021 to 2022$1,149,852July 1, 2019June 30, 2024ETHIER, C ROSSreporter.nih.gov
Deciphering the role of Lmod2 in cardiac muscle and in dilated cardiomyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,147,217April 1, 2015January 31, 2025GREGORIO, CAROL Creporter.nih.gov
The Phase I/II Randomized, Prospective, Double-blinded, Sham-controlled Cross-over Study of Intravitreal Autologous Bone Marrow CD34+ Stem Cell Therapy for Retinal Vein OcclusionNIHNational Eye Institute2021 to 2022$1,146,789June 15, 2018May 31, 2026PARK, SUSANNA Sreporter.nih.gov
Modeling alcohol toxicity in human hepatocytesNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$1,144,125September 5, 2019June 30, 2025DE JONG, YPE PETERreporter.nih.gov
Perturbation of Host DNA Replication and Cell Cycle Progression by Zika VirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,136,450July 1, 2019June 30, 2026TANG, HENGLIreporter.nih.gov
The histone demethylase JMJD1C in human Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2023$1,135,709May 16, 2019April 30, 2024ZHU, NANreporter.nih.gov
The Role of DPP in Dental Pulp Stem Cells and its Potential in Tissue RegenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,135,491April 1, 2019September 30, 2025GEORGE, ANNEreporter.nih.gov
IRS function in breast cancer progressionNIHNational Cancer Institute2021 to 2023$1,134,142July 1, 2019June 30, 2024SHAW, LESLIE Mreporter.nih.gov
Tissue Tension, RANK and Breast Cancer RiskNIHNational Cancer Institute2021 to 2022$1,132,981February 9, 2018January 31, 2024WEAVER, VALERIE MARIEreporter.nih.gov
The role of lamin B1 in normal and myelodysplastic hematopoiesisNIHNational Heart, Lung, and Blood Institute2023 to 2024$1,129,384July 1, 2023May 31, 2027DOULATOV, SERGEIreporter.nih.gov
Gestational Iron Deficiency disrupts neural patterning in the embryoNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$1,128,846September 1, 2018June 30, 2025MAYER-PROSCHEL, MARGOTreporter.nih.gov
Combination treatment of ischemic stroke with perlecan DV and neural stem cellsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,115,919December 15, 2018May 31, 2023LEE, JEAN-PYOreporter.nih.gov
Interaction between Tissue Factor, Junctional Adhesion Molecule-A, and Integrin B1 to drive self-renewal in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,114,528April 1, 2020January 31, 2026HORBINSKI, CRAIG MICHAELreporter.nih.gov
Engineered and Encapsulated Stem Cells for Resected Brain TumorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,113,859March 1, 2019February 29, 2024SHAH, KHALID Areporter.nih.gov
Dissect governing factors for tumor stem cell dormancy in biomimetic vascular/GBM modelNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,112,664August 1, 2018July 31, 2023ZOU, HONGYAN JENNYreporter.nih.gov
Correction of diabetic retinopathy by mitochondrial transferNIHNational Eye Institute2023 to 2024$1,109,489July 1, 2023May 3, 2024PROSHLYAKOV, DENIS Areporter.nih.gov
PRECLINICAL EVALUATION OF NANOPARTICULATE MINERALIZED COLLAGEN GLYCOSAMINOGLYCAN MATERIALS IN CALVARIAL REGENERATIONNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,107,545May 1, 2019April 30, 2025LEE, JUSTINE CHIAreporter.nih.gov
Role of Shp2 in FLT3-ITD induced leukemogenesisNIHNational Cancer Institute2021 to 2023$1,107,227April 1, 2011January 31, 2025KAPUR, REUBENreporter.nih.gov
Organoid modeling to determine and reverse age-related epigenetic changes contributing to risk of colorectal cancerNIHNational Cancer Institute2021 to 2024$1,104,519July 1, 2019December 31, 2024BAYLIN, STEPHEN B.reporter.nih.gov
Prevention of post-therapy breast cancer metastasisNIHNational Cancer Institute2021 to 2023$1,102,143April 12, 2019March 31, 2026WANG, XINHUIreporter.nih.gov
Clonal Reconstruction and Targeting of the Correa SequenceNIHNational Cancer Institute2021 to 2023$1,101,644July 19, 2019December 31, 2024MCKEON, FRANK D.reporter.nih.gov
Molecular mechanisms of SCLC initiation and detection in mice and humansNIHNational Cancer Institute2021 to 2022$1,100,684September 19, 2018August 31, 2024KRASNOW, MARK Areporter.nih.gov
Targeting a Novel Hematopoietic Stem Cell Population in Non-Human Primates for Effective and Sustained Gene TherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,096,475November 10, 2017March 31, 2022KIEM, HANS-PETERreporter.nih.gov
Optimization of small molecule integrin activators to enhance cord blood transplantNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,094,056February 15, 2022January 31, 2025VANDERSLICE, PETERreporter.nih.gov
Prebiotics to Optimize the Microbiota and Improve Outcomes of Allogeneic Hematopoietic Stem Cell TransplantationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,086,750July 1, 2020June 1, 2024SUNG, ANTHONYreporter.nih.gov
Biodegradable Matrices with Structural and Physical Cues for Interface EngineeringNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2024$1,084,031September 17, 2020June 30, 2026NUKAVARAPU, SYAMreporter.nih.gov
Elucidating and targeting subtype-specific driver in pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,083,360April 1, 2019March 31, 2024YING, HAOQIANGreporter.nih.gov
Estrogen Receptor Signaling in Hematopoietic Stem Cell Proliferation and MobilizationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,082,400August 20, 2020May 31, 2025OGURO, HIDEYUKIreporter.nih.gov
Engineered Anisotropic and Vascularized Human Cardiac PatchNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,081,932March 26, 2021June 30, 2025ZHAO, FENGreporter.nih.gov
Gene Delivery Nanoparticles to Treat GlioblastomaNIHNational Cancer Institute2021 to 2023$1,080,169December 16, 2018November 30, 2024GREEN, JORDANreporter.nih.gov
Posttranscriptional control of epidermal progenitors senescenceNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,079,289March 1, 2019August 31, 2024MANDINOVA, ANNAreporter.nih.gov
Bone Marrow Spatial Transcriptomics to Enhance In Vitro Platelet ProductionNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,076,177August 1, 2021July 31, 2025CANTOR, ALAN B.reporter.nih.gov
DNA hydroxymethylation and Tet-enzymes in the control of the skin development and hair growthNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,074,480August 1, 2019June 30, 2024BOTCHKAREV, VLADIMIR Areporter.nih.gov
Hedgehog/Gli1-targeted therapies to overcome ovarian cancer chemoresistance and disease recurrenceNIHNational Cancer Institute2021 to 2023$1,069,550February 15, 2018July 31, 2025PALLE, KOMARAIAHreporter.nih.gov
Role of lincRNAs in HSC function and leukemogenesisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,067,858January 15, 2019December 31, 2023XU, MINGJIANGreporter.nih.gov
Defining Mechanisms of Transformation Driven By the Zinc Finger Transcription Factor PLAGL2 in the Intestinal EpitheliumNIHNational Cancer Institute2021 to 2023$1,066,433April 1, 2019March 31, 2025RUBIN, DEBORAH C.reporter.nih.gov
MINE-MS for horizontal bone loss treatmentNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,063,812March 5, 2021August 31, 2023LIU, XIAOHUAreporter.nih.gov
A novel role of fascin in cancer metastasisNIHNational Cancer Institute2021 to 2023$1,063,661December 4, 2018November 30, 2024YANG, SHENGYUreporter.nih.gov
Tet2 regulation and function in glioma cell phenotype reprogrammingNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,060,500August 1, 2019May 31, 2025LATERRA, JOHN Jreporter.nih.gov
Targeting CD133 for imaging and therapy in prostate cancerNIHNational Cancer Institute2021 to 2023$1,060,004July 1, 2021June 30, 2025LEBEAU, AARON MATTHEWreporter.nih.gov
The Role of FoxQ1 in Breast Cancer Chemoprevention by Allium Constituents - R01CA219180NIHNational Cancer Institute2021 to 2023$1,059,662April 1, 2019March 31, 2025SINGH, SHIVENDRAreporter.nih.gov
IL-27 as a potential immunotherapeutic for cancerNIHNational Cancer Institute2021 to 2023$1,056,276July 1, 2019June 30, 2025BASU, SUJITreporter.nih.gov
Transcriptional response to signaling during hematopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,056,094January 15, 2019December 31, 2023ZON, LEONARD IRAreporter.nih.gov
The role of breast stem cells in breast cancer etiology and risk predictionNIHNational Cancer Institute2021 to 2023$1,053,765December 6, 2019November 30, 2024YAGHJYAN, LUSINEreporter.nih.gov
Roadmap 2.0: A randomized controlled trial using a technology-mediated platform in family caregivers of BMT patientsNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,053,000April 1, 2019March 31, 2025CHOI, SUNG WONreporter.nih.gov
Investigation of a Novel Cancer Stem Cell Population in Ependymoma.NIHNational Cancer Institute2021 to 2023$1,052,890April 1, 2019December 31, 2024FOREMAN, NICHOLAS Kreporter.nih.gov
Endocytic Trafficking of ADCs in GBM cancer stem-like cellsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,051,314April 1, 2019March 31, 2024GLADSON, CANDECE Lreporter.nih.gov
Targeting PGC-1a for the treatment of sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,050,000July 1, 2022May 31, 2026CUI, SHUAIYINGreporter.nih.gov
Tissue-Regulated Lineage-Specific Splicing in Glioblastoma PathogenesisNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,046,925September 1, 2020May 31, 2025WILLEY, CHRISTOPHER Dreporter.nih.gov
Microenvironmental Regulation of Leukemia Stem CellsNIHNational Cancer Institute2021 to 2023$1,043,956July 1, 2013May 31, 2024BHATIA, RAVIreporter.nih.gov
Cell Therapy Program with Scale-up cGMP Manufacturing of Human Corneal Stromal Stem CellsNIHNational Eye Institute2023 to 2024$1,041,848September 1, 2023June 30, 2025YAM, HIN FAIreporter.nih.gov
A Genetically Engineered Human Fetal Liver Niche as a Novel Platform for Biomanufacturing of Hematopoietic Stem CellsNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,037,088July 1, 2019June 30, 2025EBRAHIMKHANI, MO REZAreporter.nih.gov
Role of purine metabolism in chemoresistanceNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,036,875September 1, 2019June 30, 2025AHMED, ATIQUE U.reporter.nih.gov
Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,035,375June 17, 2019October 31, 2023COLAS, ALEXANDRE ROMAINreporter.nih.gov
Promoting Muscle Regeneration through Adipose SignalingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,035,159July 22, 2019June 30, 2025MEYER, GRETCHEN Areporter.nih.gov
Enhancing Venetoclax Activity in Chemoresistant Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2024$1,034,244March 1, 2020August 31, 2025GARCIA, JACQUELINE SUENreporter.nih.gov
Epigenetic drivers of cancer progressionNIHNational Cancer Institute2021 to 2023$1,032,037May 1, 1991June 30, 2025FEINBERG, ANDREW P.reporter.nih.gov
Non-canonical WNT signaling in emphysema and lung regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,027,860February 1, 2019April 30, 2025KOENIGSHOFF, MELANIEreporter.nih.gov
Investigations of menin function in Ewing sarcomaNIHNational Cancer Institute2021 to 2022$1,026,275June 1, 2020September 30, 2023LAWLOR, ELIZABETH Rreporter.nih.gov
Echogenic polymersomes for triggered contents releaseNIHNational Institute of General Medical Sciences2021 to 2023$1,024,521September 5, 2015November 15, 2024MALLIK, SANKUreporter.nih.gov
Novel Radioimmunotherapy Strategies for Prostate CancerNIHNational Cancer Institute2021 to 2023$1,020,311July 1, 2019June 30, 2025LEBEAU, AARON MATTHEWreporter.nih.gov
Strengthening epidermal defenses for the prevention of HPV infection and replicationNIHNational Cancer Institute2021 to 2023$1,017,436December 4, 2018November 30, 2023WELLS, SUSANNE Ireporter.nih.gov
The Function of EGFL6 in Ovarian Cancer Cell Biology, Tumor Initiation, and TherapyNIHNational Cancer Institute2021 to 2023$1,016,872December 1, 2018November 30, 2023BUCKANOVICH, RONALD Jreporter.nih.gov
GENETIC HETEROGENEITY AMONG HUMAN SOMATIC CELLS AND ITS ACCUMULATION WITH AGENIHNational Institute on Aging2021 to 2024$1,014,750August 1, 2020April 30, 2026HSIEH, CHIH-LINreporter.nih.gov
Towards Understanding Molecular Mechanisms of Human Hematopoietic Stem Cells' QuiescenceNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,014,000February 15, 2022January 31, 2026GHAFFARI, SAGHIreporter.nih.gov
A Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients.NIHNational Cancer Institute2021 to 2024$1,011,996September 3, 2020August 31, 2025AMONOO, HERMIONI L.reporter.nih.gov
Extending the scope of PLX-R18 for H-ARS: efficacy in special populations and DEARENIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,010,588March 8, 2018February 29, 2024ORSCHELL, CHRISTIE Mreporter.nih.gov
Single-cell multi-omic analysis of opioid-mediated HIV disease pathogenesisNIHNational Institute on Drug Abuse2023 to 2024$1,009,425September 30, 2023August 31, 2025COLLINS, KATHLEEN L.reporter.nih.gov
DNA Methylation Inhibitor Therapy for Testicular CancerNIHNational Cancer Institute2021 to 2022$1,005,756May 1, 2018April 30, 2024SPINELLA, MICHAEL Jreporter.nih.gov
Hematopoietic stem cells overcome treatment resistance to adoptive cellular therapy against malignant gliomasNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,000,782September 1, 2019June 30, 2024FLORES, CATHERINE Treporter.nih.gov
Transdermal estrogen for the treatment of bone loss in women with anorexia nervosaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$997,598September 1, 2019June 30, 2025FAZELI, POUNEH KHADEJEHreporter.nih.gov
Functional Dissection of Alzheimer's Disease Networks in Drosophila: from Association to Causal Modulators of Age-Dependent NeurodegerationNIHNational Institute on Aging2021$994,786September 15, 2017May 31, 2022BOTAS, JUANreporter.nih.gov
Bioengineering Mature Human Pluripotent Stem Cell-Derived Cardiomyocytes for Predictive Drug-Induced Toxicity TestingNIHNational Heart, Lung, and Blood Institute2021$993,756September 1, 2019May 31, 2023GEISSE, NICHOLAS ANDREWreporter.nih.gov
Aged tissue environments as drivers of oncogenic adaptation in hematopoiesisNIHNational Institute on Aging2021 to 2024$991,916January 1, 2020November 30, 2025DEGREGORI, JAMES Vreporter.nih.gov
Multi-layered Control of the Exit from StemnessNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$990,885February 1, 2019January 31, 2024LEE, CHENG-YUreporter.nih.gov
Mechanisms controlling early human lung developmentNIHNational Heart, Lung, and Blood Institute2021 to 2022$972,953August 1, 2018May 31, 2024AL-ALAM, DENISEreporter.nih.gov
Pericyte reprogramming in fibrosisNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2024$970,522August 1, 2023July 31, 2025GONZALEZ, ANJELICAreporter.nih.gov
VRC: Engineered extracellular vesicles for mild TBI-induced retinal injuryNIHNational Eye Institute2022 to 2024$967,616September 1, 2022May 31, 2026ROTH, STEVENreporter.nih.gov
A bio-engineered hepatic niche for ex vivo expansion of HSCsNIHNational Heart, Lung, and Blood Institute2021 to 2023$959,400July 16, 2021June 30, 2025PAJCINI, KOSTANDINreporter.nih.gov
Targeting LIF/LIFR in pancreatic cancerNIHNational Cancer Institute2021$956,072April 2, 2019April 30, 2023NAIR, HAREESH BABUreporter.nih.gov
Targeting Glioblastoma Stem CellsNIHNational Cancer Institute2024$954,000September 1, 2024August 31, 2031RICH, JEREMY Nreporter.nih.gov
Regulation of the Intestinal Stem Cells During RegenerationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$949,042September 1, 2019May 31, 2024BREAULT, DAVID Treporter.nih.gov
KDM1A inhibitors as novel therapeutics for glioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$947,506May 1, 2019February 28, 2025SAREDDY, GANGADHARA Rreporter.nih.gov
Glycosylation-dependent mechanisms regulating ovarian tumor cell phenotypeNIHNational Cancer Institute2021 to 2023$939,559May 15, 2014March 31, 2025BELLIS, SUSAN Lreporter.nih.gov
MYCT1 as a moderator for signaling between human HSC and their nicheNIHNational Heart, Lung, and Blood Institute2022 to 2024$936,000April 1, 2022February 28, 2026MIKKOLA, HANNA KATRI ANNIKKIreporter.nih.gov
A small molecule integrin activator to enhance cord blood transplantNIHNational Heart, Lung, and Blood Institute2021$928,941September 1, 2016February 28, 2023VANDERSLICE, PETERreporter.nih.gov
Tissue Regeneration by Engineered Extracellular VesiclesNIHNational Institute of General Medical Sciences2021 to 2022$920,284September 20, 2019May 31, 2024BRYERS, JAMES D.reporter.nih.gov
Gut microbiome communication with the bone marrow regulates intestinal inflammationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$918,980March 16, 2020June 4, 2024BURGESS, STACEY Lreporter.nih.gov
Therapeutic Targeting of Malignant Glioma Stem CellsNIHNational Cancer Institute2021$916,993August 13, 2015July 31, 2022LESNIAK, MACIEJ Sreporter.nih.gov
Targeting the Unfolded Protein Response in Leukemia Biology and Chemotherapy ResistanceNIHNational Cancer Institute2021 to 2023$916,031May 7, 2019April 30, 2024SYKES, STEPHEN MATTHEWreporter.nih.gov
Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 MedulloblastomaNIHNational Cancer Institute2021 to 2022$906,063April 4, 2011September 2, 2022WECHSLER-REYA, ROBERT J.reporter.nih.gov
Dynamic Complexity of Brain Tumor Stem Cells (R35CA197718)NIHNational Cancer Institute2021$904,608June 7, 2021August 31, 2023RICH, JEREMY Nreporter.nih.gov
Gamma delta T-cell immunotherapy for T-cell acute lymphoblastic leukemiaNIHNational Cancer Institute2021 to 2024$897,984April 1, 2020March 31, 2025RAIKAR, SUNIL SUDHIRreporter.nih.gov
Role of Quaking gene in regulating the niche-independent stemness of glioma stem cellsNIHNational Cancer Institute2021 to 2022$890,670December 1, 2017November 30, 2023HU, JIANreporter.nih.gov
The role of GPR133 in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$889,716August 1, 2018April 30, 2024PLACANTONAKIS, DIMITRIS G.reporter.nih.gov
Defining LncRNA Function in normal and Shwachman Diamond Syndrome MyelopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2022$882,500January 15, 2019December 31, 2023NOVINA, CARL Dreporter.nih.gov
Randomized Trial of Inpatient Palliative Care for Patients with Hematologic Malignancies Undergoing Hematopoietic Stem Cell TransplantationNIHNational Cancer Institute2021 to 2022$882,452August 9, 2018July 31, 2023EL-JAWAHRI, AREEJreporter.nih.gov
Elucidating Human Leukemia and T Cell Interactions within the Tumor MicroenvironmentNIHNational Cancer Institute2021 to 2024$870,112April 1, 2021March 31, 2026BACHIREDDY, PAVANreporter.nih.gov
eHealth Supported Mindfulness-based Music Therapy Intervention (eMBMT) in Hemopoietic Stem Cell Transplant PatientsNIHNational Cancer Institute2022 to 2023$865,658September 9, 2022May 31, 2025PENEDO, FRANK Jreporter.nih.gov
Re-engineering a human 3D liver tissue model for non-alcoholic fatty liver disease for drug screeningNIHNational Center for Advancing Translational Sciences2022 to 2023$865,037July 1, 2022May 31, 2024MIEDEL, MARK T.reporter.nih.gov
Targeting protein acetylation as a therapeutic approach for MDSNIHNational Heart, Lung, and Blood Institute2021 to 2022$865,000March 3, 2018February 29, 2024LI, LINGreporter.nih.gov
A Treatment Paradigm for Femoracetabular Impingement (FAI)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$849,426June 1, 2020May 31, 2023ESTES, BRADLEY Treporter.nih.gov
Targeting Glioblastoma Stem Cells through Epigenetic ReprogrammingNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$845,323June 15, 2018March 31, 2024FAN, XINGreporter.nih.gov
Hydrogels for hMSC delivery & engraftmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$844,435August 1, 2012July 31, 2024GARCIA, ANDRES Jreporter.nih.gov
The role of the ErbB4 and ErbB3 neuregulin receptors in intestinal epithelial regenerationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$843,062July 1, 2013May 31, 2025FREY, MARK Rreporter.nih.gov
GAS6-mediated alveolar bone regenerationNIHNational Institute of Dental & Craniofacial Research2022 to 2024$842,197August 1, 2022July 31, 2025DECKER, ANN MARIEreporter.nih.gov
Programmable Synthetic Organelles Built from Disordered Proteins for Cellular EngineeringNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$831,288September 15, 2019May 31, 2024GOOD, MATTHEW CHARLTONreporter.nih.gov
Defining the signaling pathways that direct adult tissue stem cells to exit multipotencyNIHNational Institute of General Medical Sciences2021 to 2022$825,000August 23, 2018July 31, 2023GUPTA, PIYUSHreporter.nih.gov
Perfusable 3D human cardiac constructs for heart regenerationNIHNational Heart, Lung, and Blood Institute2021$824,083April 1, 2018February 28, 2023ZHENG, YINGreporter.nih.gov
Metabolic Control of Hair Follicle Stem Cell Homeostasis and TumorigenesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$823,700March 12, 2018February 29, 2024LOWRY, WILLIAM Ereporter.nih.gov
A novel sulforaphane cancer preventionmechanismNIHNational Cancer Institute2021 to 2022$823,501February 15, 2018January 31, 2023ECKERT, RICHARD L.reporter.nih.gov
MNSOD ACETYLATION PROMOTES CANCER STEM CELL PHENOTYPES IN BREAST CANCERNIHNational Cancer Institute2021 to 2022$823,094August 14, 2018July 31, 2024BONINI, MARCELO G.reporter.nih.gov
CRISPR-based transistors for high throughput multiplexed monitoring of CRISPR-based editing efficiency for Sickle cells diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2023$814,602January 7, 2022November 1, 2023ARAN, KIANAreporter.nih.gov
Investigation of impaired neural stem cell activation in Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2023$813,190June 1, 2022July 31, 2023WEBB, ASHLEY Ereporter.nih.gov
Mesenchymal Stromal Cell Delivery through Cardiopulmonary Bypass in Pediatric Cardiac SurgeryNIHNational Heart, Lung, and Blood Institute2021$813,164May 21, 2019April 30, 2024ISHIBASHI, NOBUYUKIreporter.nih.gov
Dual function of HSP70 in cytoprotection of tumor cells and generation of permissive microenvironmentNIHNational Cancer Institute2021 to 2023$812,348May 1, 2021June 30, 2023KORKAYA, HASANreporter.nih.gov
Developing miR-10b targeting for glioblastomaNIHNational Cancer Institute2021 to 2022$809,591March 15, 2018February 29, 2024KRICHEVSKY, ANNA M.reporter.nih.gov
An Enabling Technology for Human Cardiomyocyte ManufacturingNIHNational Heart, Lung, and Blood Institute2022 to 2023$809,465June 1, 2022May 31, 2025LEI, YUGUOreporter.nih.gov
(PQ1) Progenitor cell malfunction, mutations and changes in microenvironment: A dynamic risk spectrum for cancer evolutionNIHNational Cancer Institute2021 to 2022$808,597September 1, 2017August 31, 2024GHOSH, MOUMITAreporter.nih.gov
Engineering Clinical Trials on a Chip for Dystrophin-Deficient Muscular DystrophyNIHNational Center for Advancing Translational Sciences2021$807,541September 1, 2020July 31, 2022KIM, DEOK-HOreporter.nih.gov
A microphysiologic multicellular organ-on-chip to inform clinical trials in FTD/ALSNIHNational Center for Advancing Translational Sciences2021$800,773July 1, 2020May 31, 2022SVENDSEN, CLIVE NIELSreporter.nih.gov
Mechanism and therapeutic potential of microglia regulation in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$800,000September 1, 2022July 31, 2024CHEN, PEIWENreporter.nih.gov
Regulation of hematopoiesis by CUX1NIHNational Heart, Lung, and Blood Institute2021 to 2022$798,096July 15, 2018June 30, 2023MCNERNEY, MEGANreporter.nih.gov
Administrative Supplement for Combining Experiments and Computer Simulation to Improve the Stem Cell Differentiation ProcessNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$795,817September 1, 2021August 31, 2023BOWLING, ALAN PAULreporter.nih.gov
CRISPR Editing of Primary Human Cells to Model and Correct Primary Immunodeficiency MutationsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$794,940July 1, 2020June 30, 2025NGUYEN, DAVID-HUY NHUreporter.nih.gov
A vascularized patient-derived iPSC liver acinus microphysiology system as an innovative precision medicine platform for optimizing clinical trial design for nonalcoholic fatty liver diseaseNIHNational Center for Advancing Translational Sciences2021$791,956July 15, 2020June 30, 2022TAYLOR, D. LANSINGreporter.nih.gov
Multi-antigen-specific CAR T cells to treat acute myeloid leukemiaNIHNational Cancer Institute2021 to 2023$789,102September 1, 2020June 30, 2024JAMES, SCOTT Ereporter.nih.gov
Cell-specific nanocarrier with endocytic and endosomolytic activities for therapeutic genome editingNIHNational Center for Advancing Translational Sciences2021$784,845August 22, 2019November 30, 2022LAM, KIT Sreporter.nih.gov
Novel humanized mouse model developed from cord blood CD34 positive HSC and autologous iPS cell derived thymusNIHNational Institute of Allergy and Infectious Diseases2021$782,684May 1, 2017April 30, 2022BREHM, MICHAEL ALLENreporter.nih.gov
Giving and receiving: A reciprocal support writing intervention to reduce symptoms during stem cell transplantNIHNational Cancer Institute2021$782,416August 1, 2018June 30, 2023RINI, CHRISTINEreporter.nih.gov
Pathobiologic Transcriptional Signatures of Pulmonary Complications in Pediatric Hematopoietic Cellular TransplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$781,263February 1, 2020January 31, 2026ZINTER, MATTHEW SCOTTreporter.nih.gov
Basal Progenitor Cells and Eosinophilic EsophagitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$780,597April 1, 2014January 31, 2023QUE, JIANWENreporter.nih.gov
Impact of Anemia and Its Treatment on Gut Injury in Preterm InfantsNIHNational Heart, Lung, and Blood Institute2023$780,398September 1, 2023May 31, 2025JOSEPHSON, CASSANDRA Dreporter.nih.gov
Engineering an Islet Thread from zwitterionically modified alginates for type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$778,391July 1, 2018April 30, 2025MA, MINGLINreporter.nih.gov
Genetic regulation of active and reserve intestinal stem cell statesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$775,304September 19, 2019June 30, 2023MAGNESS, SCOTT Treporter.nih.gov
Role of IL-10R signaling in inflammation induced exhaustion of HSC and emergence of JAK2V617F clonal hematopoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$773,862September 25, 2022June 30, 2025FLEISCHMAN, ANGELA GOFFREDOreporter.nih.gov
Stem Cell-based Platform for Targeted Enzyme/Prodrug Therapy of Recurrent Ovarian CancerNIHNational Cancer Institute2021 to 2022$771,552April 1, 2021March 31, 2023HATEFI, ARASHreporter.nih.gov
Juvenile microRNAs promoting healthier adult agingNIHNational Institute on Aging2021 to 2022$770,000April 1, 2018March 31, 2023SLACK, FRANK J.reporter.nih.gov
Immune Compromised Zebrafish for Cell TransplantationNIHOffice of the Director, National Institutes of Health2021$769,909August 1, 2013June 30, 2022LANGENAU, DAVID MICHAELreporter.nih.gov
Anti-CD38 targeted alpha emitter radioimmunotherapy to eliminate multiple myelomaNIHNational Cancer Institute2022 to 2023$769,415March 8, 2017December 31, 2023GREEN, DAMIAN J.reporter.nih.gov
Oxygen generating bioinks for 3D printed bone implantsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$768,975September 17, 2018June 30, 2024SHIN, SU RYONreporter.nih.gov
Controlling Influences of Oxygen Tension and CD26/DPP4 Enzymatic Activity on Regulation of Hematopoietic Stem/Progenitor Cells and Hematopoiesis During Health, Ageing, and DiseaseNIHNational Heart, Lung, and Blood Institute2021$768,104May 1, 2018April 30, 2022BROXMEYER, HAL E.reporter.nih.gov
Stem cell self-renewal programs in rhabdomyosarcomaNIHNational Cancer Institute2021 to 2022$763,179January 10, 2018December 31, 2022LANGENAU, DAVID MICHAELreporter.nih.gov
DNA Methylation at N6-Adenine in Placental Trophoblast DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$761,382August 1, 2020September 30, 2022JIANG, ZONGLIANGreporter.nih.gov
Pericyte Mechanisms in Traumatic Brain InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$761,262June 15, 2018March 31, 2024LO, ENG H.reporter.nih.gov
Identifying the human skeletal stem cell.NIHNational Institute of Dental & Craniofacial Research2021 to 2022$761,230August 6, 2018July 31, 2024LONGAKER, MICHAEL Treporter.nih.gov
Biosynthetic Metabolic Pathway Regulation of Glioma GrowthNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$758,612December 15, 2017November 30, 2023HJELMELAND, ANITA BORTONreporter.nih.gov
Regulation of Metastatic Development by Heritable Variants in the Tumor MicroenvironmentNIHNational Cancer Institute2021 to 2023$758,560December 1, 2017November 30, 2024HURLEY, PAULA JILLreporter.nih.gov
Functional Activation and Targeting of Exosomes for Regenerative MedicineNIHNational Institute of Dental & Craniofacial Research2021 to 2022$755,728July 15, 2018May 31, 2025RAVINDRAN, SRIRAMreporter.nih.gov
The role of BCAM-positive cells in central cornea, limbus and conjunctivaNIHNational Eye Institute2024$753,189August 1, 2024May 31, 2029SASAMOTO, YUZURUreporter.nih.gov
Identifying and characterizing human pulmonary neuroendocrine stem cells and their diversityNIHNational Heart, Lung, and Blood Institute2024$752,555September 24, 2024August 31, 2025KUO, CHRISTIN SUCHENGreporter.nih.gov
Alleviating Reactive Carbonyl Species-Induced Progenitor Cell Dysfunction in Diabetic Wound HealingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$749,504August 2, 2019July 31, 2024WANG, JIEMEIreporter.nih.gov
Mechanisms and targeting of inflammatory cytokine-driven expansion and progression in AMLNIHNational Cancer Institute2021 to 2023$749,285March 1, 2019February 28, 2025AGARWAL, ANUPRIYAreporter.nih.gov
Hyperpolarized Micro-NMR for Quantitative Analysis of Metabolism in Leukemia Stem CellsNIHNational Cancer Institute2021 to 2023$747,000March 1, 2018December 31, 2024JEONG, SANGMOOreporter.nih.gov
A universal genome editing strategy to develop an airway stem cell therapy for cystic fibrosisNIHNational Heart, Lung, and Blood Institute2022 to 2024$747,000September 1, 2022August 31, 2025VAIDYANATHAN, SRIRAMreporter.nih.gov
Characterizing the pathogenesis and targeted therapeutics of Wilms' Tumor 1 (WT1) mutations in AMLNIHNational Cancer Institute2021 to 2023$746,999April 1, 2019July 31, 2024ZHANG, HAIJIAOreporter.nih.gov
MicroRNAs, ER Stress and Arsenic NeurotoxicityNIHNational Institute of Environmental Health Sciences2021 to 2023$746,994February 5, 2021January 31, 2025PARK, HAE-RYUNGreporter.nih.gov
Nanowired human isogenic cardiac organoids to treat acute myocardial ischemia/reperfusion injuriesNIHNational Heart, Lung, and Blood Institute2023 to 2024$745,982August 1, 2023July 31, 2025MEI, YINGreporter.nih.gov
Bioactive cellulose-nanodiamond (CeND) scaffolds for applications in craniofacial bone tissue regenerationNIHNational Institute of General Medical Sciences2021 to 2022$745,000September 1, 2019August 31, 2025NICOLAU, EDUARDOreporter.nih.gov
Prometastatic Effects of Neoadjuvant Chemotherapy in Breast CancerNIHNational Cancer Institute2022 to 2024$744,673September 14, 2022August 31, 2025KARAGIANNIS, GEORGE Sreporter.nih.gov
Exercise-induced skeletal muscle exosomes promote adipocyte lipolysisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$744,574September 19, 2018July 31, 2024MCCARTHY, JOHN JOSEPHreporter.nih.gov
Hematopoietic Stem Cell And Cord Blood TransplantationNIHNational Institute of Allergy and Infectious Diseases2021$743,524September 30, 2005March 31, 2022PETERSDORF, EFFIE Wreporter.nih.gov
Screening for DNA Damage Response Modulators in Glioblastoma Stem CellsNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$742,584September 15, 2020July 31, 2025BADR, CHRISTIAN ELIASreporter.nih.gov
(PQ4) - Tools for simultaneous disruption of multiple epigenetically silenced genes for studying their roles in tumorigenesis using ex vivo human and mouse colon organoid and in vivo mouse modelsNIHNational Cancer Institute2021 to 2022$741,665September 1, 2018August 31, 2024EASWARAN, HARIHARANreporter.nih.gov
Targeting CD83 to reduce leukemia relapse and GVHD after allogeneic hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2023$741,625April 1, 2023August 31, 2023BETTS, BRIAN Creporter.nih.gov
Granulocyte-Macrophage Colony Stimulated Factor (GM-CSF) in Peripheral Arterial DiseaseNIHNational Heart, Lung, and Blood Institute2021$740,646August 15, 2017July 31, 2024QUYYUMI, ARSHED Areporter.nih.gov
Polysaccharide putty formulations for tissue regenerationNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2024$740,633July 1, 2023December 31, 2024KUMBAR, SANGAMESH GURAPPAreporter.nih.gov
Understanding the Role of Somatic Mutations in Adult Inflammatory DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$739,530January 1, 2022December 31, 2025BECK, DAVIDreporter.nih.gov
Targeting tumor and its microenvironment using nanotherapeutics for pancreatic cancerNIHNational Cancer Institute2021 to 2022$737,469August 1, 2020September 30, 2022RACHAGANI, SATYANARAYANAreporter.nih.gov
Dissecting gene dysregulation at the maternal-fetal interface in preeclampsiaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$737,270July 1, 2018December 31, 2023FISHER, SUSAN J.reporter.nih.gov
Targeting tumor and its microenvironment using nanotherapeutics for pancreatic cancerNIHNational Cancer Institute2023 to 2024$736,832August 1, 2020April 30, 2026RACHAGANI, SATYANARAYANAreporter.nih.gov
Targeting Metabolic Liabilities of Leukemia-Initiating CellsNIHNational Cancer Institute2021 to 2023$733,740February 1, 2019March 31, 2023XU, JIANreporter.nih.gov
Highly Specific ZFN-Based HSC Gene Editing Therapies Identified By In Vivo Barcode Nanoparticle Screens And Rationally Designed MrnaNIHNational Center for Advancing Translational Sciences2021$733,169September 16, 2019September 14, 2022DAHLMAN, JAMESreporter.nih.gov
Targeted inactivation of HIV in CNS reservoirsNIHNational Institute of Mental Health2021$732,093April 20, 2017January 31, 2023CANNON, PAULA Mreporter.nih.gov
The role of glutaminolysis as a therapeutic target in T-ALLNIHNational Cancer Institute2021 to 2022$727,426July 1, 2019June 30, 2023HERRANZ, DANIELreporter.nih.gov
The Role of Wnt2b in Intestinal HealthNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$726,020January 15, 2020December 31, 2024OCONNELL, AMY Ereporter.nih.gov
Crosstalk between leukemic blasts and the BM microenvironment contribute to leukemic transformationNIHNational Cancer Institute2022 to 2023$725,739March 4, 2022March 2, 2023DORRANCE, ADRIENNE M.reporter.nih.gov
Functional validation of sequence variants affecting neurodevelopmental and craniofacial phenotypesNIHNational Institute of Dental & Craniofacial Research2022$725,353September 26, 2022September 30, 2025CORCES, VICTOR G.reporter.nih.gov
Dissecting the Roles and Requirements for RBM39 in Acute Myeloid Leukemia and Normal HematopoiesisNIHNational Cancer Institute2022 to 2024$724,902July 1, 2022June 30, 2025LU, SYDNEY Xreporter.nih.gov
3D Bioprinting of Biomimetic Constructs for Rotator Cuff AugmentationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$720,530June 1, 2018October 31, 2024DUAN, BINreporter.nih.gov
Prognostic biomarkers for respiratory failure post hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$719,304September 1, 2020July 31, 2025ROWAN, COURTNEYreporter.nih.gov
Hematopoietic stem cell gene therapy for infantile neuronal ceroid lipofuscinosisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$717,826August 21, 2018April 30, 2023WILLIAMS, DAVID Areporter.nih.gov
Computational approaches for identifying epigenomic contexts of somatic mutationsNIHNational Institute of General Medical Sciences2021 to 2022$715,500April 1, 2019March 31, 2023DE, SUBHAJYOTIreporter.nih.gov
Bispecific and Trispecific Anti-Env Antibodies for Eliminating HIV Reservoir CellsNIHNational Institute of Allergy and Infectious Diseases2021$713,872July 10, 2017June 30, 2023HO, DAVID Dreporter.nih.gov
Molecular mechanisms for bone marrow failure and clonal progression during the innate immune response in Fanconi AnemiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$711,302April 1, 2019January 31, 2024EKLUND, ELIZABETH ANNreporter.nih.gov
Environmental Arsenic in the Subtype Specification of Breast CancerNIHNational Institute of Environmental Health Sciences2021 to 2022$710,620June 30, 2020August 31, 2024BONINI, MARCELO G.reporter.nih.gov
Use of forward Genetic approaches to identify Babesia receptorsNIHNational Heart, Lung, and Blood Institute2021$710,081December 15, 2017November 30, 2022LOBO, CHERYL ANNreporter.nih.gov
The role of inflammation in driving leukemogenesis in germline predisposition syndromesNIHNational Cancer Institute2022$707,850May 1, 2022April 30, 2023GODLEY, LUCY ANNreporter.nih.gov
Personalized vaccine for patients with AMLNIHNational Cancer Institute2021 to 2022$707,845December 9, 2016May 31, 2024AVIGAN, DAVID E.reporter.nih.gov
The Functional Role of LGR5 in Colon CancerNIHNational Cancer Institute2021 to 2022$706,563April 1, 2017January 31, 2024WANG, JINGreporter.nih.gov
A Human Organoid Model of Polycystic Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$706,000September 15, 2018June 30, 2023FREEDMAN, BENJAMIN SOLOMONreporter.nih.gov
Mechanisms and therapeutic targeting of colon cancer stem cell plasticityNIHNational Cancer Institute2021 to 2022$704,550April 1, 2018March 31, 2025CARMON, KENDRA S.reporter.nih.gov
Regulation of Lipid Catabolism by Autophagy in Neural Stem Cell of Tuberous Sclerosis ComplexNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$702,188July 15, 2018June 30, 2024WANG, CHENRANreporter.nih.gov
Developing an optimized cell based platform for assays of the gastrointestinal enteroendocrine systemNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$699,341August 1, 2019June 30, 2023SIMS, CHRISTOPHER ELDRIDGEreporter.nih.gov
Muscarinic Receptor Type 3 Regulation of Oligodendrocyte Progenitor DifferentiationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$697,812December 1, 2017November 30, 2023SIM, FRASER JAMESreporter.nih.gov
Hyperbaric oxygen to improve blood count recovery in Auto-HCT for myelomaNIHNational Cancer Institute2021 to 2022$695,162April 1, 2018March 31, 2025ALJITAWI, OMARreporter.nih.gov
Direct and Indirect Neurogenesis in the Mammalian NeocortexNIHNational Institute of Neurological Disorders and Stroke2024$693,662May 1, 2024April 30, 2029HAYDAR, TARIK Freporter.nih.gov
A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation with Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients with Severe Aplastic AnemiaNIHNational Heart, Lung, and Blood Institute2022$692,343April 1, 2022March 31, 2023WILLIAMS, DAVID Areporter.nih.gov
Hematopoietic Stem Cell Gene Therapy for Friedreich's ataxiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$691,250September 1, 2018June 30, 2023CHERQUI, STEPHANIEreporter.nih.gov
Genotypic Interactions in Brain Cancer HeterogeneityNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$690,794September 1, 2012January 31, 2023FURNARI, FRANKreporter.nih.gov
Understanding how ZFHX4 drives the glioblastoma tumor propagating cell stateNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$689,062July 1, 2018May 31, 2024CHHEDA, MILAN GIRISHreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Columbia University Health SciencesNew York, NY25$34.1 million0$0
University of Michigan at Ann ArborAnn Arbor, MI33$30.1 million0$0
University of California, San FranciscoSan Francisco, CA23$26.4 million0$0
Massachusetts General HospitalBoston, MA26$26.3 million0$0
Albert Einstein College of MedicineBronx, NY12$25.8 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA22$25.7 million0$0
Boston Children's HospitalBoston, MA15$24.8 million0$0
University of Nebraska Medical CenterOmaha, NE7$23.6 million0$0
Baylor College of MedicineHouston, TX7$23.3 million0$0
University of California, San DiegoLa Jolla, CA25$23 million0$0
Beckman Research Institute/city of HopeDuarte, CA15$22 million0$0
Stanford UniversityStanford, CA32$19.6 million0$0
Johns Hopkins UniversityBaltimore, MD29$18.8 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY15$18.5 million0$0
University of TX MD Anderson Can CTRHouston, TX25$18.2 million0$0
University of California Los AngelesLos Angeles, CA23$18.1 million0$0
University of Kansas Medical CenterKansas City, KS5$17.5 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH14$16.8 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY14$16 million0$0
Duke UniversityDurham, NC16$15.9 million0$0
Emory UniversityAtlanta, GA22$15.5 million0$0
Weill Medical Coll of Cornell UnivNew York, NY13$14 million0$0
University of Alabama at BirminghamBirmingham, AL10$14 million0$0
Fred Hutchinson Cancer CenterSeattle, WA12$13.2 million0$0
Brigham and Women's HospitalBoston, MA14$13.1 million0$0
Northwestern University at ChicagoChicago, IL14$12.2 million0$0
University of WashingtonSeattle, WA12$11.9 million0$0
Washington UniversitySaint Louis, MO17$11.6 million0$0
University of PennsylvaniaPhiladelphia, PA17$11.5 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA9$10.7 million0$0
Yale UniversityNew Haven, CT9$10.5 million0$0
University of California-BerkeleyBerkeley, CA3$10.1 million0$0
New York University School of MedicineNew York, NY8$9.7 million0$0
Dana-Farber Cancer InstBoston, MA11$9.1 million0$0
Ohio State UniversityColumbus, OH11$8.4 million0$0
University of Wisconsin-MadisonMadison, WI8$7.5 million0$0
Vanderbilt University Medical CenterNashville, TN5$7.2 million0$0
Methodist Hospital Research InstituteHouston, TX3$7.2 million0$0
University of Colorado DenverAurora, CO14$7.2 million0$0
University of ChicagoChicago, IL8$7 million0$0
Children's Research InstituteWashington, DC4$7 million0$0
University of California at DavisDavis, CA7$6.8 million0$0
University of IowaIowa City, IA4$6.7 million0$0
Lurie Children's Hospital of ChicagoChicago, IL4$6.7 million0$0
University of California-IrvineIrvine, CA8$6.6 million0$0
J. David Gladstone InstitutesSan Francisco, CA3$6.6 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA8$6.5 million0$0
Cornell UniversityIthaca, NY4$6.4 million0$0
University of ArizonaTucson, AZ2$6.1 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA6$6.1 million0$0
University of VirginiaCharlottesville, VA6$5.7 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA3$5.6 million0$0
University of MinnesotaMinneapolis, MN7$5.6 million0$0
University of RochesterRochester, NY7$5.6 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC12$5.5 million0$0
Altis Biosystems, Inc.Durham, NC6$5.4 million0$0
Medical University of South CarolinaCharleston, SC7$5.4 million0$0
University of FloridaGainesville, FL7$5.3 million0$0
Indiana University IndianapolisIndianapolis, IN11$5.2 million0$0
Children's Hospital of Los AngelesLos Angeles, CA4$5.2 million0$0
University of Maryland BaltimoreBaltimore, MD8$5.2 million0$0
University of Illinois at ChicagoChicago, IL10$5.1 million0$0
Case Western Reserve UniversityCleveland, OH8$4.9 million0$0
University of HoustonHouston, TX4$4.8 million0$0
University of Texas Med BR GalvestonGalveston, TX3$4.8 million0$0
University of Southern CaliforniaLos Angeles, CA9$4.7 million0$0
Dorian Therapeutics, Inc.San Carlos, CA2$4.5 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA5$4.4 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA4$4.1 million0$0
Magee-Women's Res Inst and FoundationPittsburgh, PA2$4.1 million0$0
Boston University Medical CampusBoston, MA4$4.1 million0$0
University of Colorado at BoulderBoulder, CO3$3.9 million0$0
Michigan State UniversityEast Lansing, MI6$3.9 million0$0
Broad Institute, Inc.Cambridge, MA2$3.8 million0$0
Tufts University BostonBoston, MA3$3.8 million0$0
Mayo Clinic RochesterRochester, MN5$3.8 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH6$3.8 million0$0
Versiti Blood Health, Inc.Milwaukee, WI3$3.8 million0$0
University of UtahSalt Lake City, UT4$3.7 million0$0
University of Miami School of MedicineCoral Gables, FL6$3.7 million0$0
Rhode Island HospitalProvidence, RI4$3.7 million0$0
Phoenicia Biosciences, Inc.Weston, MA1$3.5 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX5$3.5 million0$0
Mayo Clinic JacksonvilleJacksonville, FL6$3.4 million0$0
Fred Hutchinson Cancer Research CenterSeattle, WA9$3.2 million0$0
ST. Jude Children's Research HospitalMemphis, TN9$3.1 million0$0
University of ConnecticutStorrs, CT3$3.1 million0$0
Roswell Park Cancer Institute CorpBuffalo, NY2$3.1 million0$0
Georgia Tech Research CorporationAtlanta, GA4$3.1 million0$0
Regenerative Research FoundationAlbany, NY2$3 million0$0
Ut Southwestern Medical CenterDallas, TX8$2.9 million0$0
Institute for Systems BiologySeattle, WA2$2.8 million0$0
University of Connecticut SCH of Med/dntFarmington, CT5$2.7 million0$0
Wake Forest University Health SciencesWinston-Salem, NC6$2.7 million0$0
H. Lee Moffitt Cancer CTR & Res InstTampa, FL2$2.6 million0$0
University of Texas HLTH Science CenterSan Antonio, TX5$2.6 million0$0
University of CincinnatiCincinnati, OH2$2.6 million0$0
Steadman Philippon Research InstituteVail, CO1$2.6 million0$0
North Carolina State UniversityRaleigh, NC3$2.6 million0$0
National Jewish HealthDenver, CO2$2.5 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20256$17,185,7320$0
2024328$146,218,9320$0
2023540$233,704,1840$0
2022699$302,467,2130$0
2021840$372,689,1770$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 2 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.839December 3, 2026Not listedSame assistance listing 93.839 as 115 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.839December 3, 2026Not listedSame assistance listing 93.839 as 115 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.839December 4, 2026Not listedSame assistance listing 93.839 as 115 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.839January 5, 2027Not listedSame assistance listing 93.839 as 115 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.839January 5, 2027Not listedSame assistance listing 93.839 as 115 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.839January 7, 2027$375,000Same assistance listing 93.839 as 115 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.839January 7, 2027Not listedSame assistance listing 93.839 as 115 awards here
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)PAR-25-025NIH93.839February 3, 2027$1.5 millionSame assistance listing 93.839 as 115 awards here
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)PAR-25-026NIH93.839February 3, 2027Not listedSame assistance listing 93.839 as 115 awards here
Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)PAR-27-125NIH93.839February 16, 2027Not listedSame assistance listing 93.839 as 115 awards here
Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)RFA-DK-27-108NIH93.839March 10, 2027$500,000Same assistance listing 93.839 as 115 awards here
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)PAR-25-032NIH93.839March 16, 2027Not listedSame assistance listing 93.839 as 115 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.839April 5, 2027Not listedSame assistance listing 93.839 as 115 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.839April 5, 2027Not listedSame assistance listing 93.839 as 115 awards here
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)RFA-OD-25-003NIH93.839April 9, 2027$200,000Same assistance listing 93.839 as 115 awards here
NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)RFA-HL-26-002NIH93.839April 28, 2027Not listedSame assistance listing 93.839 as 115 awards here
NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)RFA-HL-26-003NIH93.839April 28, 2027Not listedSame assistance listing 93.839 as 115 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIH93.839May 7, 2027Not listedSame assistance listing 93.839 as 115 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIH93.839May 7, 2027Not listedSame assistance listing 93.839 as 115 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.