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Data / Research funding / California / Sanford Burnham Prebys Medical Discovery Institute

Sanford Burnham Prebys Medical Discovery Institute: 139 NIH awards ($266.3M), fiscal years 2021 to 2026

Sanford Burnham Prebys Medical Discovery Institute in La Jolla, CA is funded under 139 NIH awards ($266.3M) in the NIH and NSF award files, read 2026-11-03. NIH fiscal years 2021 to 2025; NSF fiscal years 2022 to 2026.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

139 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Administrative Supplement to Cancer Center Support Grant (CCSG)NIHNational Cancer Institute2021 to 2025$21,104,098September 1, 2025August 31, 2026BOUTROS, PAUL CHRISTOPHERreporter.nih.gov
Protein Glycosylation in the Coagulopathy and Inflammation of SepsisNIHNational Heart, Lung, and Blood Institute2021 to 2025$13,399,280July 15, 2016May 31, 2026MARTH, JAMEYreporter.nih.gov
Aging as a Risk Factor and Target for Prevention of Liver CancerNIHNational Institute on Aging2021 to 2025$12,828,172September 15, 2021August 31, 2027ADAMS, PETER D.reporter.nih.gov
Spatial Mapping Senescent Cells Across the Mouse Lifespan by Multiplex Transcriptomics and EpigenomicsNIHNational Institute on Aging2022 to 2025$10,836,434August 1, 2022July 31, 2027ADAMS, PETER D.reporter.nih.gov
Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in SmokersNIHNational Institute on Drug Abuse2023 to 2025$9,048,057September 30, 2023August 31, 2026COSFORD, NICHOLAS DAVIDreporter.nih.gov
Clinical development of an mGlu2 positive allosteric modulator to treat nicotine addictionNIHNational Institute on Drug Abuse2021 to 2022$7,715,052August 15, 2020July 31, 2025COSFORD, NICHOLAS DAVIDreporter.nih.gov
Characterization, optimization, and development of dual mGlu2/3 positive allosteric modulators for opioid use disorderNIHNational Institute on Drug Abuse2022$6,445,203July 15, 2022June 30, 2025COSFORD, NICHOLAS DAVIDreporter.nih.gov
Development of SBI-553, an allosteric modulator of NTR1, for the treatment of substance use disordersNIHNational Institute on Drug Abuse2023 to 2024$6,363,247September 30, 2019August 31, 2025JACKSON, MICHAELreporter.nih.gov
Reversing Immune Dysfunction for HIV-1 EradicationNIHNational Institute of Allergy and Infectious Diseases2021$5,001,807August 16, 2021October 31, 2021CHANDA, SUMIT Kreporter.nih.gov
Role of hypernutrition and metabolic stress in non-alcoholic steatohepatitis (NASH) driven hepatocellular carcinoma (HCC)NIHNational Cancer Institute2024 to 2025$4,700,110September 9, 2024August 31, 2029KAUFMAN, RANDAL J.reporter.nih.gov
Altered reverse transcriptase-dependent gene diversification mechanisms in Alzheimer's disease brainsNIHNational Institute on Aging2021 to 2024$3,919,959April 1, 2020January 31, 2026CHUN, JEROLDreporter.nih.gov
Transformative research on somatic gene recombination in the normal and Alzheimer's disease-related dementia brainNIHNational Institute on Aging2021 to 2024$3,698,056September 11, 2020May 31, 2026CHUN, JEROLDreporter.nih.gov
Preclinical discovery of novel farnesyltransferase inhibitors for the treatment of Alzheimer's disease and related tauopathiesNIHNational Institute on Aging2022 to 2025$3,572,381February 15, 2022November 30, 2025OLSON, STEVEN Hreporter.nih.gov
A Pharmacochaperone-based strategy for identifying chemical probes of brain-derived orphan GPCRsNIHNational Institute of Mental Health2021 to 2024$3,440,042June 5, 2020March 31, 2025JACKSON, MICHAELreporter.nih.gov
Genetic Control of Cardiac Development: Congenital Heart Disease Gene Discovery in DrosophilaNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,338,929August 1, 1995June 30, 2025BODMER, ROLFreporter.nih.gov
Mechanisms that couple irregular development of fetal melanoblasts to premature exhaustion of adult melanocyte stem cellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,102,648August 4, 2021May 31, 2027ADAMS, PETER D.reporter.nih.gov
Defining chromostasis - a candidate regulator of healthy aging and longevityNIHNational Institute on Aging2021 to 2024$3,049,633September 11, 2020May 31, 2025ADAMS, PETER D.reporter.nih.gov
Fragment-Based Discovery of STEP Modulators in Alzheimer's Disease Administrative SupplementNIHNational Institute on Aging2024 to 2025$2,947,358May 15, 2024April 30, 2027TAUTZ, LUTZreporter.nih.gov
Comparative resistomics of Gram-negative bacterial pathogensNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,934,000January 10, 2022December 31, 2026OSTERMAN, ANDREI Lreporter.nih.gov
"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"NIHNational Institute on Aging2021 to 2023$2,920,747March 1, 2019December 31, 2024KAUFMAN, RANDAL J.reporter.nih.gov
Regulation and Function of Stromal Macropinocytosis in Pancreatic Ductal AdenocarcinomaNIHNational Cancer Institute2021 to 2025$2,871,428September 1, 2021August 31, 2026COMMISSO, COSIMOreporter.nih.gov
Elucidating a microgliaassociated role for SORLA in modulating AD pathogenesisNIHNational Institute on Aging2022$2,818,493August 1, 2022July 31, 2025HUANG, TIMOTHY YIKAIreporter.nih.gov
Brain-penetrant GPR88 agonists as novel therapeutics for opioid abuseNIHNational Institute on Drug Abuse2022 to 2025$2,795,026August 1, 2022July 31, 2027JACKSON, MICHAELreporter.nih.gov
New Down syndrome brain organization revealed by single-cell genomicsNIHNational Institute on Aging2021 to 2022$2,758,286September 15, 2021June 30, 2024CHUN, JEROLDreporter.nih.gov
New Congenital Disorders of Glycosylation: Therapy and ModelsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,728,508May 1, 2014July 31, 2029FREEZE, HUDSON H.reporter.nih.gov
Molecular pathobiology of soluble TREM2 in Alzheimer's diseaseNIHNational Institute on Aging2023$2,655,773April 1, 2017August 31, 2026HUANG, TIMOTHY YIKAIreporter.nih.gov
Characterizing the nuclear pore complex-T cell receptor connectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,614,348December 16, 2019February 28, 2025DANGELO, MAXIMILIANO Areporter.nih.gov
Pathogenic Alterations of the 3D Epigenetic Landscape in Dystrophin-Deficient Skeletal Muscles and Reversal by Dystrophin Re-ExpressionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,541,743August 1, 2009May 31, 2027PURI, PIER LORENZOreporter.nih.gov
Role of Fbxw7-Mediated Proteasomal Degradation in Myofibers in Determining Muscle Stem Cell Pool SizeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,494,858July 1, 2020December 31, 2026SACCO, ALESSANDRAreporter.nih.gov
Optimization of Drug-like Properties of CRFBP-CRF2 Negative Allosteric Modulators for Alcohol Use DisorderNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$2,438,146September 20, 2023August 31, 2028SHEFFLER, DOUGLAS Jreporter.nih.gov
Eph Receptor Heterointeractions in SignalingNIHNational Institute of General Medical Sciences2021 to 2025$2,424,019January 1, 2019May 31, 2027PASQUALE, ELENA Breporter.nih.gov
Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and DiseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,422,875February 1, 2021January 31, 2026MARTH, JAMEYreporter.nih.gov
Overriding the Immune Evasion Tactics of CoronavirusNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,422,685August 12, 2020July 31, 2025WARE, CARL Freporter.nih.gov
Glycosyltransferase Function in Development and DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,418,000September 15, 1994March 31, 2027MARTH, JAMEYreporter.nih.gov
EPHA2 Receptor Signaling in Breast Cancer MechanotransductionNIHNational Cancer Institute2022 to 2025$2,315,344June 1, 2022May 31, 2027PASQUALE, ELENA Breporter.nih.gov
Microglial heparan sulfate in the modulation of APOE function and neurodegenerationNIHNational Institute on Aging2022 to 2025$2,312,221February 1, 2022November 30, 2026YAMAGUCHI, YUreporter.nih.gov
Improving Proinsulin Folding to Ameliorate Type II DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,300,175May 5, 2023April 30, 2027KAUFMAN, RANDAL J.reporter.nih.gov
Regulation of Nutrient Stress-Induced Macropinocytosis in Pancreatic Ductal AdenocarcinomaNIHNational Cancer Institute2021 to 2025$2,288,727July 1, 2016August 31, 2026COMMISSO, COSIMOreporter.nih.gov
Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,285,106December 8, 2021November 30, 2025SERGIENKO, EDUARD A.reporter.nih.gov
Discovery of Selective Inhibitors for the EphA4 KinaseNIHNational Institute on Aging2021 to 2023$2,272,757March 15, 2020December 31, 2024SERGIENKO, EDUARD A.reporter.nih.gov
Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventionsNIHNational Institute on Aging2021 to 2025$2,263,786May 1, 2021February 28, 2027ADAMS, PETER D.reporter.nih.gov
Function and Mechanism of the Hippo-PI5P4K Axis for Growth ControlNIHNational Institute of General Medical Sciences2022 to 2025$2,247,650July 1, 2022June 30, 2026EMERLING, BROOKE M.reporter.nih.gov
Rewired Signaling at the Nexus of Melanoma Metastasis and ResistanceNIHNational Cancer Institute2021 to 2022$2,234,009February 2, 2016January 31, 2023RONAI, ZEEV A.reporter.nih.gov
Brain pathology and function in a chronic mouse model of ZIKV transmissionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,965,040April 1, 2019March 31, 2024TERSKIKH, ALEXEY Vreporter.nih.gov
Discovery of small molecule regulators of atrial cardiomyocyte action potential duration to restore normal cardiac rhythm in atrial fibrillationNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,950,000June 10, 2021August 31, 2025COLAS, ALEXANDRE ROMAINreporter.nih.gov
Molecular mechanisms underlying the assembly of the human proteasome and endogenous protein complexesNIHNational Institute of General Medical Sciences2022 to 2025$1,950,000August 1, 2022July 31, 2027ZHAO, JIANHUAreporter.nih.gov
Investigation of ecDNA as a driver of intratumoral heterogeneity and treatment resistance in high-risk medulloblastomaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,914,963September 1, 2023August 31, 2028CHAVEZ, LUKASreporter.nih.gov
Discovery of Novel Inhibitors Targeting trans-Golgi Network Acidification in Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,905,554March 22, 2023February 28, 2027COMMISSO, COSIMOreporter.nih.gov
GCDH Addiction in MelanomaNIHNational Cancer Institute2022 to 2024$1,859,149July 1, 2022September 30, 2024RONAI, ZEEV A.reporter.nih.gov
Discovery and development of apoE4 correctors for the treatment of Alzheimer's diseaseNIHNational Institute on Aging2023 to 2024$1,800,549September 15, 2023May 31, 2025JACKSON, MICHAELreporter.nih.gov
Targeting neuroinflammation in AD with novel CX3CR1 agonistsNIHNational Institute on Aging2021 to 2023$1,794,217May 1, 2019February 28, 2025OLSON, STEVEN Hreporter.nih.gov
Molecular Pathogenesis of AF10-Rearranged LeukemiasNIHNational Cancer Institute2022 to 2025$1,767,803April 12, 2022March 31, 2027DESHPANDE, ANIRUDDHA J.reporter.nih.gov
Development of STEP Allosteric Inhibitors as Novel Therapeutics for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$1,754,034September 15, 2020May 31, 2024TAUTZ, LUTZreporter.nih.gov
Non-Canonical Phosphatidylinositol Kinases in Triple Negative Breast CancerNIHNational Cancer Institute2021 to 2024$1,753,027June 1, 2020May 31, 2025EMERLING, BROOKE Mreporter.nih.gov
Targeting the FBXO44/SUV39H1 Pathway in CancerNIHNational Cancer Institute2022 to 2025$1,748,680December 10, 2021November 30, 2026SPRUCK, CHARLES H.reporter.nih.gov
Targeting ER+ Breast Cancer Through Induced Viral MimicryNIHNational Cancer Institute2022 to 2025$1,748,680April 1, 2022March 31, 2027SPRUCK, CHARLES H.reporter.nih.gov
Novel Neuroprotective Roles for the Alzheimer's Disease Risk Gene SORLA in Tau Pathology and PathogenesisNIHNational Institute on Aging2024 to 2025$1,714,215December 1, 2023November 30, 2028HUANG, TIMOTHY YIKAIreporter.nih.gov
Discovery of Potent Selective Inhibitors of the Histone Methyltransferase SUV39H1 for the Treatment of CancerNIHNational Cancer Institute2024 to 2025$1,618,482July 1, 2024June 30, 2029SPRUCK, CHARLES H.reporter.nih.gov
Discovery and optimization of ApoE4 correctors for the treatment of Alzheimer's DiseaseNIHNational Institute on Aging2024 to 2025$1,608,116August 1, 2024July 31, 2029JACKSON, MICHAELreporter.nih.gov
Retinoic acid target genes and transcriptional mechanisms during eye developmentNIHNational Eye Institute2021 to 2024$1,548,300June 1, 2021May 31, 2026DUESTER, GREGG Lreporter.nih.gov
Genetic Pathways in Ceramide-Associated Lipotoxic Cardiomyopathy and Heart FailureNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,462,500December 10, 2019May 31, 2024BODMER, ROLFreporter.nih.gov
Regulation of Blood Glycoproteins by Lectin Receptors in Health and DiseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,462,500April 1, 2023March 31, 2027MARTH, JAMEYreporter.nih.gov
Novel roles for the Alzheimer's Disease (AD) risk gene, SORLA in neuroprotection in ADNIHNational Institute on Aging2021 to 2022$1,362,387September 30, 2018May 31, 2024HUANG, TIMOTHY YIKAIreporter.nih.gov
Identifying and Targeting the Drivers of Pediatric Brain TumorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,353,600May 1, 2021August 31, 2022WECHSLER-REYA, ROBERT J.reporter.nih.gov
Rewiring T cell exhaustion with immune checkpoint blockade therapyNIHNational Cancer Institute2024 to 2025$1,349,992August 7, 2024July 31, 2029BRADLEY, LINDA MAC PHERSONreporter.nih.gov
Dissecting the Intracellular and Extracellular Role of TREM2 in the Pathogenesis of Non-Alcoholic Steatohepatitis.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,326,264August 15, 2023June 30, 2027DHAR, DEBANJANreporter.nih.gov
Denervation activated super-enhancers of pathogenic IL6-STAT3 feedforward loop in FAPsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,269,840August 1, 2019October 31, 2024PURI, PIER LORENZOreporter.nih.gov
Augmented Notch signaling as a therapeutic approach for Alagille SyndromeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$1,269,840August 1, 2022May 31, 2027DONG, P. DUC SIreporter.nih.gov
Optimization of fibroblast-selective inhibitors of YAP/TAZ as novel therapeutics for Pulmonary FibrosisNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,262,407February 1, 2022January 31, 2024HEYNEN-GENEL, SUSANNEreporter.nih.gov
Hormetic regulation of autophagy in agingNIHNational Institute on Aging2024 to 2025$1,161,467July 15, 2024June 30, 2029KUMSTA, CAROLINEreporter.nih.gov
Regulation of PDAC metabolism and immunity by collagen and its cleavage productsNIHNational Cancer Institute2025$1,152,768September 1, 2025August 31, 2027KARIN, MICHAELreporter.nih.gov
Macropinocytosis Inhibition as a Glutamine Mimetic Sensitization Strategy in Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,127,010July 17, 2024June 30, 2029COMMISSO, COSIMOreporter.nih.gov
Membrane Protein Effectors of Pathogen Interactions With HostNIHNational Institute of General Medical Sciences2021 to 2022$1,063,700June 1, 2016September 30, 2022MARASSI, FRANCESCA Mreporter.nih.gov
Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,035,375June 17, 2019October 31, 2023COLAS, ALEXANDRE ROMAINreporter.nih.gov
Identification of small molecule modulators of mitochondrial creatine kinase 1NIHNational Cancer Institute2021 to 2022$988,051May 8, 2020April 30, 2024SERGIENKO, EDUARD A.reporter.nih.gov
Ubiquitin D as a potential therapeutic target for NASH, HCC and chronic kidney diseasesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$980,000August 1, 2023May 31, 2028DHAR, DEBANJANreporter.nih.gov
Mechanisms of hematopoietic acute radiation syndrome induction and radioprotection through sphingosine 1-phosphate receptor 1 signal modulationNIHNational Heart, Lung, and Blood Institute2021 to 2022$975,000September 7, 2018December 31, 2023BLAHO, VICTORIA ALISONreporter.nih.gov
Novel Strategy to Quantitate Delayed Aging by Caloric RestrictionNIHNational Institute on Aging2022 to 2023$959,826February 15, 2022January 31, 2024TERSKIKH, ALEXEY Vreporter.nih.gov
The Development of TGR5 Antagonists for the Treatment of CholangiopathiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$945,769September 15, 2019June 30, 2023OLSON, STEVEN Hreporter.nih.gov
Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 MedulloblastomaNIHNational Cancer Institute2021 to 2022$906,063April 4, 2011September 2, 2022WECHSLER-REYA, ROBERT J.reporter.nih.gov
Elucidating a microgliaassociated role for SORLA in modulating AD pathogenesisNIHNational Institute on Aging2025$867,404August 1, 2022July 31, 2027HUANG, TIMOTHY YIKAIreporter.nih.gov
The extrahepatopancreatic ducts as a novel source of hepatic progenitorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$858,000September 1, 2020August 31, 2023DONG, P. DUC SIreporter.nih.gov
S1P signaling machinery in neuroimmune interactionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$853,126April 15, 2018January 31, 2024KIHARA, YASUYUKIreporter.nih.gov
MYOD Regulation of 3D Chromatin StructureNIHNational Institute of General Medical Sciences2021 to 2022$780,000July 8, 2019December 31, 2023PURI, PIER LORENZOreporter.nih.gov
Control of gene expression in neural stem cells by crosstalk between messenger RNA methylation and histone modificationNIHNational Institute of General Medical Sciences2021 to 2022$780,000August 1, 2019May 31, 2023BAGCHI, ANINDYAreporter.nih.gov
Screening for Inhibitors of the Chromatin Reader SGF29NIHNational Cancer Institute2025$768,437April 8, 2025March 31, 2028DESHPANDE, ANIRUDDHA J.reporter.nih.gov
Spatial Regulators of Skeletal Muscle Regeneration and DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$738,702September 30, 2020February 28, 2026WANG, YU XINreporter.nih.gov
Lead optimization of novel CRFBP-CRFR2 complex modulators for alcohol use disorderNIHNational Institute on Alcohol Abuse and Alcoholism2021$733,411May 1, 2019September 30, 2023SHEFFLER, DOUGLAS Jreporter.nih.gov
A new mouse model for studying the pathogenesis and immunobiology of intrahepatic cholangiocarcinoma and improving its immunotherapyNIHNational Cancer Institute2025$695,955September 19, 2023August 31, 2028KARIN, MICHAELreporter.nih.gov
Linking the microbiome and immune-checkpoint in melanoma by RNF5NIHNational Cancer Institute2021$603,580March 15, 2017August 31, 2022BRADLEY, LINDA MAC PHERSONreporter.nih.gov
Acquisition of Zeiss LSM980 with Airyscan 2, a super-resolution point scanning confocal microscopeNIHOffice of the Director, National Institutes of Health2023$600,000June 5, 2023June 4, 2024KAUFMAN, RANDAL J.reporter.nih.gov
Optimization of fibroblast-selective inhibitors of YAP/TAZ as novel therapeutics for Pulmonary FibrosisNIHNational Heart, Lung, and Blood Institute2024$596,061May 1, 2024April 30, 2026HEYNEN-GENEL, SUSANNEreporter.nih.gov
Beckman Coulter Biomek i7 Hybrid automated workstationNIHOffice of the Director, National Institutes of Health2024$594,187April 1, 2024March 31, 2025HUANG, CHUN-TENGreporter.nih.gov
Innate Immune Surveillance of HIV-1 During Transmission and Systemic InfectionNIHNational Institute of Allergy and Infectious Diseases2021$563,051February 28, 2017March 2, 2022CHANDA, SUMIT Kreporter.nih.gov
Exploratory Therapy for the Skeletal/Dental Phenotype in PHOSPHO1 DeficiencyNIHNational Institute of Dental & Craniofacial Research2022 to 2023$550,625March 11, 2022February 28, 2025MILLAN, JOSE LUISreporter.nih.gov
Characterizing a potential role for TREM2 in modulating tau pathogenesis in response to AbetaNIHNational Institute on Aging2021 to 2022$536,250March 1, 2021August 31, 2023HUANG, TIMOTHY YIKAIreporter.nih.gov
Targeting the VHR phosphatase for the treatment of sepsis in COVID-19 patientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$536,250April 6, 2021September 30, 2023TAUTZ, LUTZreporter.nih.gov
Epigenetic drift of the Aging Heart in DrosophilaNIHNational Institute on Aging2022 to 2023$536,250August 1, 2022October 31, 2024GUIDA, MARIA CLARAreporter.nih.gov
Transcriptional activation of RCOR2 as a novel oncogenic mechanism in supratentorial ependymomaNIHNational Institute of Neurological Disorders and Stroke2022$536,250January 7, 2023August 31, 2025CHAVEZ, LUKASreporter.nih.gov
The Aging Pancreas as a Pro-tumorigenic NicheNIHNational Institute on Aging2024 to 2025$536,250September 1, 2024August 31, 2026COMMISSO, COSIMOreporter.nih.gov
A knowledge-guided analysis approach to recovering rare signals from single-cell transcriptomic dataNIHNational Institute of General Medical Sciences2025$536,250July 1, 2025June 30, 2027YIP, YUK-LAP KEVINreporter.nih.gov
Collagen fibers and fragments regulate pancreatic cancer metabolism and growthNIHNational Cancer Institute2025$532,713March 1, 2024February 28, 2029KARIN, MICHAELreporter.nih.gov
The NRF2-FBP1 crossregulatory loop and the control of healthy and diseased liver metabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$508,692August 1, 2022May 31, 2027KARIN, MICHAELreporter.nih.gov
Cancer Targets and Drug DiscoveryNIHNational Cancer Institute2021 to 2022$500,346July 3, 2018June 30, 2024COSFORD, NICHOLAS DAVIDreporter.nih.gov
Epigenetic Reprogramming to Counteract Neuronal Aging and DegenerationNIHNational Institute on Aging2024 to 2025$493,018August 1, 2020January 31, 2027TIAN, XIAOreporter.nih.gov
Optimization and Characterization of "MYC Degraders" for Pediatric MedulloblastomaNIHNational Institute of Neurological Disorders and Stroke2022$487,500May 15, 2020April 30, 2023JACKSON, MICHAELreporter.nih.gov
Multi-strain, live biotherapeutics as adjuncts to checkpoint inhibitor therapyNIHNational Cancer Institute2021 to 2022$475,782May 17, 2021April 30, 2023KIM, HYUNGSOOreporter.nih.gov
Cytek Aurora Full Spectrum Flow CytometerNIHOffice of the Director, National Institutes of Health2022$468,316September 20, 2022June 19, 2024ALTMAN, YOAVreporter.nih.gov
Factors Regulating Development of Appendicular Skeletal ProgenitorsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$429,000February 11, 2015August 31, 2024DUESTER, GREGG Lreporter.nih.gov
Development and Implementation of Advanced Technologies for Cancer Metabolism ResearchNIHNational Cancer Institute2023 to 2025$426,096August 1, 2023July 31, 2028SCOTT, DAVID ANDERSONreporter.nih.gov
Testing the utility of miBioAge as a personalized aging biomarkerNIHNational Institute on Aging2023$399,786September 15, 2023March 31, 2024TERSKIKH, ALEXEY Vreporter.nih.gov
Role of Epigenetically Active Environmental Compounds in Neurodevelopmental DisordersNIHNational Institute of Environmental Health Sciences2021 to 2022$390,000April 21, 2021March 31, 2024TERSKIKH, ALEXEY Vreporter.nih.gov
Early development of small molecule dendritic cell immunopotentiators for the treatment of solid tumorsNIHNational Cancer Institute2021$370,994July 11, 2018September 30, 2021CHANDA, SUMIT Kreporter.nih.gov
Rewired Signaling at the Nexus of Melanoma Metastasis and ResistanceNIHNational Cancer Institute2024$343,564August 1, 2024September 30, 2024RONAI, ZEEV A.reporter.nih.gov
Frontiers in Fundamental and Translational ImmunologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$338,622February 1, 2018June 2, 2023BRADLEY, LINDA MAC PHERSONreporter.nih.gov
Regulation of CD4+ T Cell Responses During Chronic Viral InfectionNIHNational Institute of Allergy and Infectious Diseases2021$338,409June 18, 2020November 15, 2022BRADLEY, LINDA MAC PHERSONreporter.nih.gov
NF-kappaB and Mitochondrial Signals as Positive and Negative Regulators of InflammationNIHNational Institute of Allergy and Infectious Diseases2025$313,960June 1, 2023May 31, 2028KARIN, MICHAELreporter.nih.gov
Regulation of the tumor microenvironment by DNA damage repair proteinsNIHNational Cancer Institute2023$313,073July 14, 2023January 15, 2024HARICHARAN, SVASTIreporter.nih.gov
Digital Spatial Profiler Analysis InstrumentNIHOffice of the Director, National Institutes of Health2021$302,469April 15, 2021April 14, 2022ADAMS, PETER D.reporter.nih.gov
Identification of microproteins associated with hematopoiesis and related diseasesNIHNational Heart, Lung, and Blood Institute2025$292,500August 15, 2025July 31, 2027YIP, YUK-LAP KEVINreporter.nih.gov
Immune Checkpoint Blockade Targeting the Novel PSGL-1/VISTA Axis for Pancreatic CancerNIHNational Cancer Institute2025$268,345March 10, 2025February 28, 2027BRADLEY, LINDA MAC PHERSONreporter.nih.gov
A Role of Astrocyte and Microglia Interplay in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$261,168July 1, 2020September 29, 2022JIANG, LU-LINreporter.nih.gov
Control of Lipogenesis and Hepatic Steatosis by Caspase-2NIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$253,699March 15, 2019April 30, 2027KARIN, MICHAELreporter.nih.gov
Evaluation of a High-Affinity and BTLA-specific HVEM Protein Agonist in vivoNIHNational Institute of Allergy and Infectious Diseases2021$243,750December 12, 2019March 31, 2022WARE, CARL Freporter.nih.gov
Phenotypic Screening for Longevity Interventions Using Single-cell Epigenetic SignaturesNIHNational Institute on Aging2021$243,750August 1, 2020May 31, 2022TERSKIKH, ALEXEY Vreporter.nih.gov
A screen for small molecule inhibitors of CCF to suppress senescence-associated inflammationNIHNational Institute on Aging2021$243,750August 15, 2020November 30, 2022ADAMS, PETER D.reporter.nih.gov
Role of Epigenetically Active Environmental Compounds in Neurodevelopmental DisordersNIHNational Institute of Environmental Health Sciences2021$243,750September 25, 2020August 31, 2022TERSKIKH, ALEXEY Vreporter.nih.gov
Mitonuclear signaling pathways in senescence-associated inflammationNIHNational Institute on Aging2022 to 2023$235,958September 15, 2022August 31, 2025MILLER, KARL NATHANreporter.nih.gov
Nuclear pore regulation of leukemia cell metabolism and survivalNIHNational Cancer Institute2021$227,906December 1, 2019February 28, 2022RAICES, MARCELAreporter.nih.gov
Modulation of metabolism in TILs by the checkpoint inhibitor PSGL-1NIHNational Cancer Institute2021$227,906February 18, 2020January 31, 2022BRADLEY, LINDA MAC PHERSONreporter.nih.gov
The Macropinosome: Uncovering the Molecular Anatomy of an Oncogene-driven OrganelleNIHNational Cancer Institute2021$227,906May 1, 2020April 30, 2023COMMISSO, COSIMOreporter.nih.gov
Identifying novel networks of candidate Atrial Fibrillation genes in the Drosophila cardiac aging modelNIHNational Heart, Lung, and Blood Institute2021 to 2023$216,348April 1, 2021March 31, 2024KEZOS, JAMESreporter.nih.gov
Transcriptional activation of LAMC1 as a resistance mechanism in recurrent PFA EpendymomaNIHNational Institute of Neurological Disorders and Stroke2022$195,948January 7, 2023May 31, 2024CHAVEZ, LUKASreporter.nih.gov
Targeting Checkpoint Inhibition in Anti-Tumor ResponsesNIHNational Cancer Institute2021 to 2022$195,000May 1, 2021April 30, 2023BRADLEY, LINDA MAC PHERSONreporter.nih.gov
Mechanisms of Aging: Regulation of Canonical and Non-canonical AutophagyNIHNational Institute on Aging2021$136,350August 1, 2019June 30, 2023NIETO-TORRES, JOSE LUISreporter.nih.gov
The role of the CCR4-NOT complex in the regulation of Nuclear Pore Complex assemblyNIHNational Cancer Institute2022 to 2023$71,146August 1, 2022March 30, 2024SAKUMA, STEPHENreporter.nih.gov
Role of HDAC7 in senescence-associated inflammationNIHNational Institute on Aging2021$70,458September 12, 2019September 11, 2022MILLER, KARL NATHANreporter.nih.gov
PIKfyve regulates pH homeostasis and tumor growth in pancreatic cancerNIHNational Cancer Institute2025$40,810May 16, 2025May 15, 2028GRENIER DAVIS, SHEAreporter.nih.gov
Disruption of a DNA loop as a complementary mechanism of H3.3K27M mutationsNIHNational Institute of Neurological Disorders and Stroke2021$21,986January 7, 2023May 31, 2023CHAVEZ, LUKASreporter.nih.gov

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
202557$45,310,3250$0
202461$52,478,7360$0
202361$52,830,5570$0
202280$64,198,5120$0
202171$51,437,0270$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 6 awards here
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)PAR-25-095NIH93.866November 6, 2026$350,000Same assistance listing 93.866 as 33 awards here
Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)RFA-AG-27-010NIH93.866November 10, 2026Not listedSame assistance listing 93.866 as 33 awards here
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)PAR-25-096NIH93.866November 17, 2026$200,000Same assistance listing 93.866 as 33 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.866November 23, 2026$375,000Same assistance listing 93.866 as 33 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317NIH93.866November 24, 2026Not listedSame assistance listing 93.866 as 33 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.866December 3, 2026Not listedSame assistance listing 93.866 as 33 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.866December 3, 2026Not listedSame assistance listing 93.866 as 33 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.866December 4, 2026Not listedSame assistance listing 93.866 as 33 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)PAR-27-039NIH93.866January 5, 2027Not listedSame assistance listing 93.866 as 33 awards here
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)PAR-27-040NIH93.866January 5, 2027Not listedSame assistance listing 93.866 as 33 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.866January 7, 2027$375,000Same assistance listing 93.866 as 33 awards here
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)PAR-25-378NIH93.866January 7, 2027Not listedSame assistance listing 93.866 as 33 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.866January 7, 2027Not listedSame assistance listing 93.866 as 33 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.866January 15, 2027$350,000Same assistance listing 93.866 as 33 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.866January 22, 2027Not listedSame assistance listing 93.866 as 33 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.866January 26, 2027Not listedSame assistance listing 93.866 as 33 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.866January 26, 2027Not listedSame assistance listing 93.866 as 33 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.866January 27, 2027$500,000Same assistance listing 93.866 as 33 awards here
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)RFA-NS-24-031NIH93.866January 28, 2027$750,000Same assistance listing 93.866 as 33 awards here

Topics of its NIH awards

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.