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Data / Research funding / Brain Disorders

Brain Disorders: 26,960 NIH awards ($37.6B) to 1,664 organizations

26,960 NIH awards ($37.6B) in the NIH spending category Brain Disorders, to 1,664 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 26,960 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Health and Retirement Study: Yrs 35-40NIHNational Institute on Aging2021 to 2025$142,220,153September 25, 1990December 31, 2029WEIR, DAVID R.reporter.nih.gov
Alzheimer's Clinical Trials Consortium (ACTC)NIHNational Institute on Aging2021 to 2025$119,771,576December 2, 2017August 31, 2028AISEN, PAUL S.reporter.nih.gov
Alzheimer's Disease Neuroimaging Initiative (ADNI4)NIHNational Institute on Aging2022 to 2025$95,332,786September 30, 2004July 31, 2028WEINER, MICHAEL Wreporter.nih.gov
Alzheimer Biomarker Consortium - Down Syndrome (ABC-DS)NIHNational Institute on Aging2021 to 2025$82,684,947September 30, 2020August 31, 2026HANDEN, BENJAMIN Lreporter.nih.gov
DIAN-TU Primary Prevention TrialNIHNational Institute on Aging2021 to 2025$79,373,454September 15, 2018May 31, 2026MCDADE, ERIC MARTINreporter.nih.gov
NIA AD/ADRD Health Care Systems Research CollaboratoryNIHNational Institute on Aging2021 to 2025$69,169,841September 1, 2019August 31, 2030MOR, VINCENTreporter.nih.gov
Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD ProjectNIHNational Institute on Aging2022 to 2025$66,521,567September 1, 2022August 31, 2027LUCHSINGER, JOSE ALEJANDROreporter.nih.gov
NIDA Clinical Trials Network: New York Node (CTN-0139, CTN-0155, CTN-Biostats)NIHNational Institute on Drug Abuse2021 to 2025$66,452,521March 1, 2025February 29, 2032MCNEELY, JENNIFERreporter.nih.gov
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)NIHNational Institute on Aging2021 to 2025$65,403,220July 15, 2002May 31, 2027FOROUD, TATIANA M.reporter.nih.gov
The National Health and Aging Trends Study and National Study of CaregivingNIHNational Institute on Aging2021 to 2025$65,386,641September 30, 2008March 31, 2029SCHRACK, JENNIFER ANNreporter.nih.gov
ProNET: Psychosis-Risk Outcomes NetworkNIHNational Institute of Mental Health2021 to 2025$61,984,741September 8, 2020May 31, 2026WOODS, SCOTT Wreporter.nih.gov
The Alzheimer's Disease Tau Platform Clinical TrialNIHNational Institute on Aging2023 to 2024$60,700,604September 21, 2023August 31, 2028BOXER, ADAM L.reporter.nih.gov
ADRC Consortium for Clarity in ADRD Research Through ImagingNIHNational Institute on Aging2023 to 2024$60,357,563September 15, 2023August 31, 2028JOHNSON, STERLING Creporter.nih.gov
The Long Life Family StudyNIHNational Institute on Aging2021 to 2025$60,108,132August 15, 2019June 30, 2030PROVINCE, MICHAEL A.reporter.nih.gov
CTN New England Consortium NodeNIHNational Institute on Drug Abuse2021 to 2025$58,365,118March 1, 2025February 29, 2032D'ONOFRIO, GAILreporter.nih.gov
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)NIHNational Institute on Aging2021 to 2025$56,766,232September 15, 2019August 31, 2030BOEVE, BRADLEY Freporter.nih.gov
NRG Oncology NCORP Research Base-BIQSFPNIHNational Cancer Institute2021 to 2025$54,340,726July 11, 2025July 31, 2026BRUNER, DEBORAH WATKINSreporter.nih.gov
Access for All in ALS (ALL ALS) West Clinical Coordinating CenterNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$51,203,440September 25, 2023June 30, 2027BOWSER, ROBERT Preporter.nih.gov
DIAN-TU: Tau Next Generation Prevention TrialNIHNational Institute on Aging2021 to 2025$49,839,335September 15, 2020May 31, 2027BATEMAN, RANDALL Jreporter.nih.gov
Access for All in ALS (ALL ALS) East Clinical Coordinating CenterNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$49,098,369September 25, 2023June 30, 2027BERRY, JAMES DALEreporter.nih.gov
A multimodal brain cell atlas and community resource of Alzheimer's disease and comorbid dementias.NIHNational Institute on Aging2021 to 2025$48,445,852March 1, 2020August 31, 2030LEIN, EDreporter.nih.gov
National Alzheimer's Coordinating CenterNIHNational Institute on Aging2021 to 2025$45,845,722June 15, 2021May 31, 2027STEPHENS, KARI Areporter.nih.gov
IU/JAX/PITT MODEL-AD CenterNIHNational Institute on Aging2021 to 2025$45,129,948September 30, 2016August 31, 2027LAMB, BRUCE Treporter.nih.gov
NIDA Clinical Trials Network: Big South/West Node (CTN-0132 and CTN-0139)NIHNational Institute on Drug Abuse2021 to 2025$43,417,361March 1, 2025February 28, 2032TRIVEDI, MADHUKAR H.reporter.nih.gov
Longitudinal multicenter head-to-head harmonization of tau PET tracersNIHNational Institute on Aging2021 to 2025$41,111,092September 1, 2021May 31, 2027PASCOAL, THARICKreporter.nih.gov
UC Irvine MODEL-ADNIHNational Institute on Aging2021 to 2025$40,119,354September 15, 2017August 31, 2027LAFERLA, FRANK Mreporter.nih.gov
Randomized Double Blind, Placebo Controlled, Parallel Group Trial to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease over 18 MonthsNIHNational Institute on Aging2021 to 2025$39,702,286June 1, 2020May 31, 2027CAGGIANO, ANTHONY Oreporter.nih.gov
Wisconsin longitudinal study: Initial lifetime's impact on Alzheimer's disease and related disorders (WLS-ILIAD)NIHNational Institute on Aging2021 to 2025$39,317,019September 15, 2018February 29, 2028ASTHANA, SANJAYreporter.nih.gov
Limited Competition: Continuation of the Center for Genomic Studies on Mental DisordersNIHNational Institute of Mental Health2021 to 2024$39,202,732July 1, 2003February 28, 2026KNOWLES, JAMES Areporter.nih.gov
Study of Muscle, Mobility and Aging: SOMMA2NIHNational Institute on Aging2021 to 2025$38,028,895June 15, 2018June 30, 2029CUMMINGS, STEVEN RONreporter.nih.gov
Alzheimer's Disease Sequencing Project Phenotype Harmonization ConsortiumNIHNational Institute on Aging2021 to 2025$37,497,984September 30, 2021August 31, 2026HOHMAN, TIMOTHY Jreporter.nih.gov
Cognitive training to reduce incidence of cognitive impairment in older adultsNIHNational Institute on Aging2021 to 2024$37,326,564February 1, 2021January 31, 2027O'BRIEN, JENNIFER LEEreporter.nih.gov
Health and Aging Brain among Latino Elders (HABLE-AT(N)) StudyNIHNational Institute on Aging2021 to 2025$36,277,689August 1, 2020April 30, 2027O'BRYANT, SID Ereporter.nih.gov
Randomized, Double-Blind, Placebo-Controlled, Phase 3 StudyNIHNational Institute on Aging2021 to 2024$36,190,244August 15, 2020May 31, 2025ABUSHAKRA, SUSANreporter.nih.gov
Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)NIHNational Institute on Drug Abuse2021 to 2022$36,092,167April 17, 2019March 31, 2025WALSH, SHARON L.reporter.nih.gov
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)NIHNational Institute on Aging2022 to 2025$35,910,792July 1, 2022June 30, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
The Neighborhoods Study: Contextual Disadvantage and Alzheimer’s Disease and Related Dementias (ADRD)NIHNational Institute on Aging2021 to 2025$35,388,433March 1, 2021May 31, 2026KIND, AMY J.reporter.nih.gov
The Emory Healthy Brain Study: Discovering Predictive Biomarkers for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$35,158,235February 15, 2021January 31, 2027LAH, JAMES Jreporter.nih.gov
Combination anti-amyloid therapy for preclinical Alzheimer's diseaseNIHNational Institute on Aging2021 to 2024$34,903,050September 30, 2018May 31, 2025AISEN, PAUL S.reporter.nih.gov
A Next Generation Data Infrastructure to Understand Disparities across the Life CourseNIHNational Institute on Aging2023 to 2025$34,372,705August 15, 2023July 31, 2028KAPTEYN, ARIEreporter.nih.gov
FY25 AWARD. NIDA DEVELOPMENTAL STUDIES BIOREPOSITORY AND ANALYSIS CENTER. SEPTEMBER 17, 2025 - SEPTEMBER 16, 2026. N01DA-21-5588. TASK ORDER 75N95025F00001 (TO5).NIHNational Institute on Drug Abuse2021 to 2025$34,168,377September 17, 2025September 16, 2026reporter.nih.gov
CCC TO 11 - CTN-0145: STANDARD VERSUS HIGH DOSE ED-INITIATED BUPRENORPHINE INDUCTION. POP: 8/28/23 - 8/27/27.NIHNational Institute on Drug Abuse2021 to 2025$33,434,913August 28, 2023August 27, 2026JELSTROM, EVEreporter.nih.gov
Pediatric Eye Disease Investigator Group Coordinating CenterNIHNational Eye Institute2021 to 2025$33,066,572May 1, 1997December 31, 2028KRAKER, RAYMONDreporter.nih.gov
Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral SclerosisNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$33,014,143September 25, 2023April 30, 2027BERRY, JAMES DALEreporter.nih.gov
Education and Cognitive Functioning in Later Life: The Nation’s High School Class of 1972NIHNational Institute on Aging2024 to 2025$32,776,590September 30, 2022July 31, 2027MULLER, CHANDRA Lreporter.nih.gov
Early Onset AD Consortium - the LEAD Study (LEADS)NIHNational Institute on Aging2021 to 2023$31,594,379September 30, 2018May 31, 2025APOSTOLOVA, LIANA Greporter.nih.gov
ProCAN: Psychosis Risk Outcomes Compound Assessment NetworkNIHNational Institute of Mental Health2024 to 2025$31,583,752June 14, 2024May 31, 2029WOODS, SCOTT Wreporter.nih.gov
NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) FOR THE CENTRALIZED OMICS RESOURCE (CORE)NIHNational Heart, Lung, and Blood Institute2023 to 2025$31,474,131September 26, 2025September 25, 2026reporter.nih.gov
IUSM TREAT-AD CenterNIHNational Institute on Aging2021 to 2025$31,208,587September 30, 2019November 30, 2029PALKOWITZ, ALAN D.reporter.nih.gov
Phase II randomized controlled trial of benfotiamine in early Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$30,295,384July 15, 2022June 30, 2028GIBSON, GARY Ereporter.nih.gov
The Progressive Supranuclear Palsy Clinical Trial Platform (PTP)NIHNational Institute on Aging2024 to 2025$30,281,212August 15, 2024July 31, 2029BOXER, ADAM L.reporter.nih.gov
MassHEAL - Reducing overdose deaths by 40% (2019-2023)NIHNational Institute on Drug Abuse2021 to 2023$29,970,213September 15, 2023March 31, 2024SAMET, JEFFREY H.reporter.nih.gov
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 2 Study to Evaluate the Safety and Efficacy of CT1812 in Subjects with Dementia with Lewy BodiesNIHNational Institute on Aging2021 to 2023$29,498,064May 15, 2021April 30, 2025CAGGIANO, ANTHONY Oreporter.nih.gov
Allopregnanolone as Regenerative Therapeutic for Alzheimer's: Phase 2 Clinical TrialNIHNational Institute on Aging2021 to 2025$28,784,116August 15, 2019April 30, 2027BRINTON, ROBERTA EILEENreporter.nih.gov
Generation, Characterization, and Validation of Marmoset Models of Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$28,395,368September 1, 2022August 31, 2027SILVA, AFONSO Creporter.nih.gov
An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with PridopidineNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$27,895,551September 25, 2023August 31, 2027PAGANONI, SABRINAreporter.nih.gov
Bridge Funding for Dominantly Inherited Alzheimer NetworkNIHNational Institute on Aging2021 to 2025$27,724,157September 15, 2008June 30, 2026BATEMAN, RANDALL Jreporter.nih.gov
The INCLUDE Data Coordinating CenterNIHNational Heart, Lung, and Blood Institute2021 to 2025$27,560,616September 26, 2020August 31, 2030RESNICK, ADAM CAINreporter.nih.gov
RADX BLUEPRINT MEDTECH TRANSLATOR COHORT 2 - COMMERCIALIZATION CENTER - HEALNIHNational Heart, Lung, and Blood Institute2022 to 2025$27,543,152June 2, 2025June 1, 2026reporter.nih.gov
Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular AtherostenosisNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$26,536,563September 1, 2021May 31, 2028HOH, BRIAN LIMreporter.nih.gov
A non-viral CRISPR-mediated genome editing delivery platform as a potential therapy for neurogenetic diseasesNIHNational Center for Advancing Translational Sciences2023 to 2025$26,526,303September 20, 2023July 31, 2027JIANG, YONG-HUIreporter.nih.gov
The Florida Node Alliance of the National Drug Abuse Clinical Trials Network (CTN-121)NIHNational Institute on Drug Abuse2021 to 2025$26,301,696March 1, 2025February 29, 2028SZAPOCZNIK, JOSEreporter.nih.gov
API A4 Alzheimer's Prevention TrialNIHNational Institute on Aging2021 to 2025$26,251,396September 1, 2018November 30, 2025REIMAN, ERIC MICHAELreporter.nih.gov
DSC MANAGEMENT AND SUPPORT. MARCH 1, 2025 TO FEBRUARY 28, 2026. N01DA-22-2253. TASK ORDER NO. 75N95025F00001 (TO25).NIHNational Institute on Drug Abuse2022 to 2025$25,789,598March 1, 2025February 28, 2026reporter.nih.gov
BPN-MCSP-HIT TO LEAD CHEMISTRY- MARTIN (NUVONURO)NIHNational Institute on Drug Abuse2021 to 2025$25,707,343December 9, 2024June 8, 2026MICHELS, PETER Creporter.nih.gov
ASPirin in Reducing Events in the Elderly - eXTensionNIHNational Institute on Aging2021 to 2023$24,851,437July 15, 2019April 30, 2026MURRAY, ANNE Mreporter.nih.gov
US POINTER Neuroimaging Ancillary StudyNIHNational Institute on Aging2021 to 2025$24,762,483August 1, 2019March 31, 2027LANDAU, SUSAN Mreporter.nih.gov
Precision Monitoring and Assessment in the Framingham Study: Cognitive, MRI, Genetic and Biomarker Precursors of AD & DementiaNIHNational Institute on Aging2021 to 2024$24,586,693September 15, 2020May 31, 2026FARRER, LINDSAY A.reporter.nih.gov
Center without Walls for Imaging Proteinopathies with PETNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$24,457,384September 24, 2019July 31, 2029MACH, ROBERT Hreporter.nih.gov
Asian Cohort for Alzheimer's Disease (ACAD)NIHNational Institute on Aging2023 to 2025$24,263,451July 1, 2023June 30, 2028WANG, LI-SANreporter.nih.gov
Chicago Chronic Conditions Engagement NetworkNIHNational Institute on Minority Health and Health Disparities2021 to 2025$24,257,718September 24, 2021June 30, 2027HUANG, ELBERT S.reporter.nih.gov
Metformin in Alzheimer's dementia Prevention (MAP)NIHNational Institute on Aging2021 to 2025$24,224,790August 15, 2019April 30, 2027LUCHSINGER, JOSE ALEJANDROreporter.nih.gov
Trajectories and Predictors in the Clinical High Risk for Psychosis Population: Prediction Scientific Global Consortium (PRESCIENT)NIHNational Institute of Mental Health2021 to 2025$24,090,655September 8, 2020May 31, 2026NELSON, CHRISTOPHER BARNABYreporter.nih.gov
Integrating Information about Aging Surveys: Novel Integration of Contextual Data to Study Late-Life Cognition and Alzheimer’s Disease and Related Dementia and Dementia CareNIHNational Institute on Aging2021 to 2025$23,672,206May 1, 2007March 31, 2027LEE, JINKOOKreporter.nih.gov
Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Open-Label Extension StudyNIHNational Institute on Aging2021 to 2024$23,438,396May 15, 2019December 31, 2025SPERLING, REISA A.reporter.nih.gov
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$23,431,388August 15, 2021July 31, 2027MUCKE, LENNARTreporter.nih.gov
Psychosis Risk Evaluation, Data Integration and Computational Technologies (PREDICT): Data Processing, Analysis, and Coordination CenterNIHNational Institute of Mental Health2021 to 2024$23,322,808September 9, 2020May 31, 2026SHENTON, MARTHA E.reporter.nih.gov
Interactions of SARS-CoV-2 infection and genetic variation on the risk of cognitive decline and Alzheimer’s disease in Ancestral and Admixed PopulationsNIHNational Institute on Aging2023 to 2025$23,106,653August 15, 2023July 31, 2028DE ERAUSQUIN, GABRIEL ALEJANDROreporter.nih.gov
Resilience/Resistance to Alzheimer's Disease in Centenarians and Offspring (RADCO)NIHNational Institute on Aging2021 to 2025$23,099,141September 30, 2021August 31, 2027PERLS, THOMAS Treporter.nih.gov
Intermediate-sized Expanded Access Protocol for CNM-Au8 in Amyotrophic Lateral Sclerosis (ALS).NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$22,785,879September 25, 2023August 31, 2027ANDREWS, JINSYreporter.nih.gov
Mount Sinai ECHO site for Perinatal Environment and Development StudiesNIHOffice of the Director, National Institutes of Health2021 to 2025$22,671,567September 21, 2016May 31, 2030WRIGHT, ROSALIND Jreporter.nih.gov
NorthStar Node of the NIDA Clinical Trials NetworkNIHNational Institute on Drug Abuse2021 to 2025$22,374,119September 1, 2015February 29, 2032BART, GAVINreporter.nih.gov
THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITENIHNational Institute on Aging2021 to 2025$21,982,300April 1, 2012April 30, 2027WANG, LI-SANreporter.nih.gov
REVEAL - Research Evaluating Vagal Excitation and Anatomical Linkages.NIHNational Center for Complementary & Integrative Health2022 to 2024$21,646,919September 23, 2022August 31, 2025OSBORN, JOHN Wreporter.nih.gov
Wisconsin Registry for Alzheimer's PreventionNIHNational Institute on Aging2023 to 2025$21,491,270June 1, 2023February 29, 2028JOHNSON, STERLING Creporter.nih.gov
BRAIN CONNECTS: A Center for High-throughput Integrative Mouse ConnectomicsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$21,489,807September 8, 2023August 31, 2028LICHTMAN, JEFF Wreporter.nih.gov
APOE in the Predisposition to, Protection from and Prevention of Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$21,355,638September 30, 2020March 31, 2027REIMAN, ERIC MICHAELreporter.nih.gov
SCREENING OF INVESTIGATIONAL AGENTS THROUGH THE NINDS PRECLINICAL SCREENING PLATFORM FOR PAIN (PSPP)NIHNational Institute on Drug Abuse2024 to 2025$21,254,211September 6, 2024September 5, 2026HANANIA, TALEENreporter.nih.gov
Unraveling the earliest phases of vascular cognitive impairment and dementia using CADASIL--a monogenic form of small vessel cerebrovascular diseaseNIHNational Institute on Aging2021 to 2025$21,188,740September 30, 2021August 31, 2027PAULSEN, JANE Sreporter.nih.gov
Penn Artificial Intelligence and Technology Collaboratory for Healthy AgingNIHNational Institute on Aging2021 to 2025$21,174,898September 30, 2021May 31, 2027DEMIRIS, GEORGEreporter.nih.gov
A Phase 2b Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients with Mild-to-Moderate Dementia with Lewy Bodies (DLB)NIHNational Institute on Aging2023 to 2025$21,072,036February 1, 2023January 31, 2026ALAM, JOHNreporter.nih.gov
Delaware Clinical and Translational Research ACCEL ProgramNIHNational Institute of General Medical Sciences2021 to 2025$21,011,968September 25, 2013June 30, 2028HICKS, GREGORY Ereporter.nih.gov
The Origins of Alzheimer Disease in African AmericansNIHNational Institute on Aging2022 to 2025$20,889,453September 15, 2022June 30, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
SCREENING OF INVESTIGATIONAL THERAPEUTICS TO TREAT, MODIFY OR PREVENT EPILEPSY FOR THE NINDS EPILEPSY THERAPY SCREENING PROGRAM (ETSP)NIHNational Institute on Drug Abuse2022 to 2025$20,858,598March 23, 2022December 31, 2025WILCOX, KARENreporter.nih.gov
Alzheimer's Gut Microbiome ProjectNIHNational Institute on Aging2021 to 2023$20,743,566September 15, 2019August 31, 2025KADDURAH-DAOUK, RIMA Freporter.nih.gov
Frontotemporal Dementia: Genes, Images, and EmotionsNIHNational Institute on Aging2021 to 2025$20,694,825September 1, 2002April 30, 2028GORNO TEMPINI, MARIA LUISAreporter.nih.gov
Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in Cohort of Oldest-OldNIHNational Institute on Aging2022 to 2025$20,680,832September 15, 2017June 30, 2027WHITMER, RACHEL Areporter.nih.gov
Additional Sequencing for the Alzheimer Disease Sequencing Project (ADSP) the Follow-Up Study (FUS), The Diverse Population InitiativeNIHNational Institute on Aging2022 to 2024$20,575,729September 1, 2022August 31, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
Yale Center for the Study of Tobacco Product Use and Addiction (YCSTP)NIHNational Institute on Drug Abuse2021 to 2025$20,420,182September 30, 2013August 31, 2028KRISHNAN-SARIN, SUCHITRAreporter.nih.gov
Alzheimer's Prevention Initiative ADAD Colombia Trial ProgramNIHNational Institute on Aging2024 to 2025$20,406,409September 1, 2024August 31, 2029ALEXANDER, ROBERT Creporter.nih.gov
IDeA Networks of Biomedical Research Excellence in KentuckyNIHNational Institute of General Medical Sciences2021 to 2025$20,119,568September 30, 2001April 30, 2029ROUCHKA, ERIC Creporter.nih.gov
Einstein Aging StudyNIHNational Institute on Aging2021 to 2024$20,102,748September 29, 1982March 31, 2028DERBY, CAROL A.reporter.nih.gov
South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE)NIHNational Institute of General Medical Sciences2021 to 2025$19,943,827September 30, 2001August 31, 2026GOLDSMITH, EDIE Creporter.nih.gov
Massachusetts Alzheimer's Disease Research Center (MADRC)NIHNational Institute on Aging2021 to 2025$19,915,545May 15, 2019March 31, 2029GOMEZ-ISLA, TERESAreporter.nih.gov
National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS)NIHNational Institute on Aging2021 to 2025$19,881,397August 1, 2017April 30, 2027MAYEUX, RICHARD Preporter.nih.gov
Analyses to Reveal Trajectories and Early Markers of Imminent Shifts in Suicidal StatesNIHNational Institute of Mental Health2025$19,515,757August 18, 2025August 17, 2029TURNER, JESSreporter.nih.gov
Oklahoma IDeA Network of Biomedical Research ExcellenceNIHNational Institute of General Medical Sciences2021 to 2025$19,194,069September 6, 2001August 31, 2030LANG, MARK Lreporter.nih.gov
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30NIHNational Institute on Aging2021 to 2025$18,959,959May 1, 2019March 31, 2029BREWER, JAMES Breporter.nih.gov
JCOIN Phase II Coordination and Translation CenterNIHNational Institute on Drug Abuse2021 to 2025$18,785,790September 30, 2019May 31, 2029TAXMAN, FAYE Sreporter.nih.gov
Health, Aging and Dementia in South Africa: A Longitudinal Study (HAALSI)NIHNational Institute on Aging2021 to 2025$18,706,904September 15, 2013May 31, 2028BERKMAN, LISA Freporter.nih.gov
Pediatric Brain Tumor Consortium A multi-institutional consortium devoted to novel phase I and II clinical evaluations of experimental treatment approaches for pediatric CNS tumorsNIHNational Cancer Institute2021 to 2025$18,653,803April 1, 1999March 31, 2026ONAR-THOMAS, ARZUreporter.nih.gov
The Ohio Valley Node of the Clinical Trials Network (CTN-0153)NIHNational Institute on Drug Abuse2021 to 2025$18,588,752March 1, 2025February 29, 2032WINHUSEN, T JOHNreporter.nih.gov
Mayo Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$18,486,241July 1, 2019April 30, 2029BOEVE, BRADLEY Freporter.nih.gov
Dynamic Cognitive Phenotypes for Prediction of Mental Health Outcomes in Serious Mental IllnessNIHNational Institute of Mental Health2025$18,270,924September 10, 2025September 9, 2029GERMINE, LAURA THIreporter.nih.gov
State-dependent Decision-making in Brainwide Neural CircuitsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$18,155,129August 15, 2021July 31, 2027PANINSKI, LIAM Mreporter.nih.gov
An Expanded Access Protocol of Intravenous Trehalose Injection 90 mg/mL Treatment of Patients with Amyotrophic Lateral SclerosisNIHNational Institute of Neurological Disorders and Stroke2022$18,136,504September 28, 2022August 31, 2025PAGANONI, SABRINAreporter.nih.gov
Lifecourse health, cerebral pathology and differences in dementia risk (KHANDLE Study)NIHNational Institute on Aging2021 to 2025$18,022,067June 1, 2016February 28, 2027WHITMER, RACHEL Areporter.nih.gov
Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$17,997,906May 15, 2022January 31, 2028GONZALEZ, HECTOR Mreporter.nih.gov
Bridge2AI: Voice as a Biomarker of Health - Building an ethically sourced, bioaccoustic database to understand disease like never beforeNIHOffice of the Director, National Institutes of Health2022 to 2025$17,995,278September 1, 2022November 30, 2026BENSOUSSAN, YAEL EMILIEreporter.nih.gov
Mount Sinai Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$17,735,870May 1, 2020March 31, 2030SANO, MARYreporter.nih.gov
Aging eyes and aging brains in studying alzheimer's disease: Modern ophthalmic data collection in the adult changes in thought (ACT) studyNIHNational Institute on Aging2021 to 2024$17,711,217September 1, 2019August 31, 2029LEE, CECILIA SUNGMINreporter.nih.gov
Additional Sequencing for the Alzheimer's Disease Sequencing Project (ADSP)NIHNational Institute on Aging2021 to 2024$17,661,924July 1, 2020June 30, 2026VANCE, JEFFERY MARVINreporter.nih.gov
Northeast Node of the National Drug Abuse Treatment Clinical Trials NetworkNIHNational Institute on Drug Abuse2021 to 2025$17,509,561March 1, 2025February 28, 2030MARSCH, LISA A.reporter.nih.gov
Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$17,255,961June 15, 2020April 30, 2030SMALL, SCOTT Areporter.nih.gov
Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal)NIHNational Institute on Aging2021 to 2025$17,112,209August 15, 2018May 31, 2029HUGHES, TIMOTHY M.reporter.nih.gov
Offspring Study of Mechanisms for Racial Disparities in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$17,095,138September 1, 2016May 31, 2027MANLY, JENNIFER JAIEreporter.nih.gov
NORTHWESTERN Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$17,093,229August 15, 2021June 30, 2026VASSAR, ROBERT Jreporter.nih.gov
Strategies for targeting astrocyte reactivity in Alzheimer's disease and related dementiasNIHNational Institute on Aging2022 to 2025$17,073,728September 1, 2022June 30, 2027NORRIS, CHRISTOPHER MARKreporter.nih.gov
Add Health Parent Study: A Biosocial Resource for the Study of Multigenerational Racial/Ethnic Disparities in Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD)NIHNational Institute on Aging2023 to 2025$17,039,516August 15, 2023April 30, 2028HARRIS, KATHLEEN MULLANreporter.nih.gov
Biomarkers of Cognitive Decline Among Normal Individuals: The Biocard CohortNIHNational Institute on Aging2021 to 2025$16,952,609July 1, 2009May 31, 2027ALBERT, MARILYN S.reporter.nih.gov
Goizueta Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$16,684,611July 15, 2020April 30, 2030LEVEY, ALLAN Ireporter.nih.gov
1/2 Pediatric Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)NIHNational Heart, Lung, and Blood Institute2022 to 2025$16,489,352September 15, 2021August 31, 2028MOLER, FRANK Wreporter.nih.gov
Diabetes and brain amyloid in middle aged HispanicsNIHNational Institute on Aging2021 to 2025$16,383,484September 1, 2015May 31, 2027LUCHSINGER, JOSE ALEJANDROreporter.nih.gov
Cognition & Hippocampal/Cortical Systems in AgingNIHNational Institute on Aging2021 to 2025$16,383,227September 1, 1997March 31, 2027KNIERIM, JAMES Jreporter.nih.gov
National Social Life, Health, and Aging Project: Round 5NIHNational Institute on Aging2021 to 2025$16,330,170September 15, 2014April 30, 2029WAITE, LINDA Jreporter.nih.gov
University of Kansas Alzheimer's Disease Research Center (KU ADRC)NIHNational Institute on Aging2021 to 2025$16,309,323August 15, 2021June 30, 2026SWERDLOW, RUSSELL H.reporter.nih.gov
Understanding Cohort Effects on Stroke, VCID, and Cognition After Major Epidemiologic TransitionsNIHNational Institute of Neurological Disorders and Stroke2024$16,244,011September 24, 2001August 31, 2026JUDD, SUZANNE Ereporter.nih.gov
CWRU Center for Excellence on the Impact of Substance Use on HIVNIHNational Institute on Drug Abuse2021 to 2025$16,213,687September 15, 2021May 31, 2027LEVINE, ALAN DAVIDreporter.nih.gov
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia ProjectNIHNational Institute on Aging2021 to 2025$16,156,406January 15, 2021December 31, 2026HUMMER, ROBERT Areporter.nih.gov
The Alzheimer's Disease Research Center at the University of California, IrvineNIHNational Institute on Aging2021 to 2025$16,032,156June 15, 2020March 31, 2030LAFERLA, FRANK Mreporter.nih.gov
Alzheimer's Disease Genetics ConsortiumNIHNational Institute on Aging2021 to 2024$15,948,152April 1, 2009March 31, 2026SCHELLENBERG, GERARD DAVIDreporter.nih.gov
Brain Oxygen Optimization in Severe Traumatic Brain Injury - Phase 3 (BOOST-3)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$15,805,224July 1, 2018November 30, 2025BARSAN, WILLIAM Greporter.nih.gov
Arizona Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$15,728,435September 5, 2021June 30, 2027LANGBAUM, JESSICA BROOKEreporter.nih.gov
Educational and Early Life Predictors of Mild Cognitive Impairment: New Evidence about Mediators and Moderators from High School & BeyondNIHNational Institute on Aging2021 to 2022$15,706,591May 15, 2019February 29, 2024WARREN, JOHN ROBERTreporter.nih.gov
ARIC Neurocognitive Study (ARIC-NCS) RenewalNIHNational Heart, Lung, and Blood Institute2021 to 2022$15,682,941July 7, 2010March 31, 2024CORESH, JOSEFreporter.nih.gov
Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementiasNIHNational Institute on Aging2021 to 2025$15,514,157September 30, 2021May 31, 2027ELLERBY, LISA Mreporter.nih.gov
Center for Pacific Innovations, Knowledge, and Opportunities (PIKO)NIHNational Institute of General Medical Sciences2021 to 2025$15,507,862September 1, 2021July 31, 2027KAHOLOKULA, JOSEPH KEAWE'AIMOKUreporter.nih.gov
Therapeutic Editing to Lower PrP in Prion DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$15,507,691May 17, 2023April 30, 2026VALLABH, SONIA MINIKELreporter.nih.gov
The VETSA Longitudinal Twin Study of Cognition and Aging (VETSA 4)NIHNational Institute on Aging2021 to 2024$15,274,483September 1, 2015March 31, 2026PANIZZON, MATTHEW Sreporter.nih.gov
A Phase-2b, Double-Blind, Randomized Controlled Trial to Evaluate the Activity and Safety of Inebilizumab in Anti-N-methyl-D-aspartate receptor (NMDAR) Encephalitis and Assess Markers of DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$15,144,108September 15, 2021August 31, 2027CLARDY, STACEY LYNNreporter.nih.gov
Leveraging Artificial Intelligence to Predict Mental Health Risk among Youth Presenting to Rural Primary Care ClinicsNIHNational Institute of Mental Health2025$15,039,330September 10, 2025September 9, 2029POSNER, JONATHAN Ereporter.nih.gov
Anti-NMDA Receptor Antibodies in Adult Brain Dysfunction: Lessons from LupusNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,990,990August 1, 2008June 30, 2030DIAMOND, BETTYreporter.nih.gov
The Rhythm Evaluation for Anticoagulation with Continuous Monitoring of Atrial Fibrillation Trial (REACT-AF)NIHNational Heart, Lung, and Blood Institute2023 to 2025$14,978,926August 25, 2022July 31, 2029PASSMAN, ROD Sreporter.nih.gov
NIH NATIONAL BRAIN AND TISSUE REPOSITORYNIHNational Institute on Drug Abuse2021 to 2025$14,799,056May 1, 2025October 31, 2025reporter.nih.gov
Johns Hopkins University Trial Innovation CenterNIHNational Center for Advancing Translational Sciences2023 to 2025$14,762,337July 5, 2023April 30, 2028HANLEY, DANIEL Freporter.nih.gov
English Longitudinal Study of Ageing - Renewal 2024NIHNational Institute on Aging2021 to 2025$14,720,227September 30, 2000May 31, 2029STEPTOE, ANDREWreporter.nih.gov
Alzheimer's Disease Research CentersNIHNational Institute on Aging2021 to 2025$14,719,450September 1, 2020March 31, 2030CHUI, HELENA CHANGreporter.nih.gov
Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategiesNIHNational Institute on Aging2022 to 2025$14,689,794September 15, 2019December 31, 2026PERLS, THOMAS Treporter.nih.gov
Causes and Consequences of Healthcare Inefficiency in Alzheimer’s Disease and Related DementiasNIHNational Institute on Aging2021 to 2025$14,684,279August 1, 2001July 31, 2028BARNATO, AMBER Ereporter.nih.gov
Alzheimer's Disease Research Center - Administrative Supplement 2025NIHNational Institute on Aging2021 to 2025$14,671,380May 1, 2020April 30, 2026WISNIEWSKI, THOMAS Mreporter.nih.gov
Global Alzheimer's Platform Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2022$14,626,193May 1, 2017April 30, 2024AISEN, PAUL S.reporter.nih.gov
Single cell transcriptomic and epigenomic changes during chronic HIV infection and cocaine self-administrationNIHNational Institute on Drug Abuse2022 to 2025$14,516,969June 1, 2022March 31, 2027ZENG, HONGKUIreporter.nih.gov
Advancing cross-disease comparisons through FAIR data practices to uncover shared molecular mechanisms between Alzheimer's disease and autoimmune disordersNIHNational Institute on Aging2021 to 2025$14,514,376September 1, 2025April 30, 2027HEATH, LAURA MICHELLEreporter.nih.gov
Integrative Pathways to Cognitive, Affective, and Brain HealthNIHNational Institute on Aging2022 to 2025$14,488,542September 30, 2022August 31, 2028RYFF, CAROL D.reporter.nih.gov
FVIIa for Acute hemorrhagic Stroke Administered at Earliest Time (FASTEST) TrialNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$14,427,244March 1, 2020December 31, 2026BRODERICK, JOSEPH PAULreporter.nih.gov
Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksNIHNational Institute on Aging2021 to 2024$14,414,001September 15, 2020August 31, 2025THOMPSON, PAUL Mreporter.nih.gov
Long-term effects of hearing intervention on brain health in the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) randomized studyNIHNational Institute on Aging2022 to 2025$14,339,100August 15, 2022July 31, 2028DEAL, JENNIFER ANNEreporter.nih.gov
Mild Cognitive Impairment: A Prospective Community StudyNIHNational Institute on Aging2021 to 2025$14,337,476September 1, 2005April 30, 2026GANGULI, MARYreporter.nih.gov
National Social Life, Health, and Aging Project: Rounds 4.2 and 4.4NIHNational Institute on Aging2021 to 2025$14,285,263September 1, 2013February 28, 2027WAITE, LINDA Jreporter.nih.gov
The RADAR cohort study of multilevel Influences on HIV and substance useNIHNational Institute on Drug Abuse2021 to 2025$14,251,651April 15, 2014April 30, 2030MUSTANSKI, BRIANreporter.nih.gov
Study of Healthy Aging in African AmericansNIHNational Institute on Aging2023 to 2025$14,240,222January 1, 2017May 31, 2028WHITMER, RACHEL Areporter.nih.gov
The Mobile Toolbox for Monitoring Cognitive and Behavioral Function (MTB2)NIHNational Institute on Aging2021 to 2024$14,206,304September 15, 2018May 31, 2029GERSHON, RICHARDreporter.nih.gov
Education and Cognitive Functioning in Later Life: The Nation’s High School Class of 1972NIHNational Institute on Aging2022 to 2023$14,187,625September 30, 2022July 31, 2027MULLER, CHANDRA Lreporter.nih.gov
MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS)NIHNational Heart, Lung, and Blood Institute2021 to 2025$14,117,524April 1, 2019September 30, 2026GUSTAFSON, DEBORAH R.reporter.nih.gov
Vanderbilt Memory & Aging ProjectNIHNational Institute on Aging2021 to 2025$14,019,775March 15, 2011March 31, 2027JEFFERSON, ANGELA L.reporter.nih.gov
Sleep for Stroke Management And Recovery Trial (Sleep SMART)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$13,933,376August 15, 2018April 30, 2027BROWN, DEVIN Lreporter.nih.gov
HEAL ERN: Data Coordinating Resource CenterNIHNational Center for Advancing Translational Sciences2022 to 2025$13,821,158September 23, 2022August 31, 2027WATT, KEVIN Mreporter.nih.gov
Multicultural Community Dementia ScreeningNIHNational Institute on Aging2021 to 2025$13,797,203May 1, 2021January 31, 2027GALVIN, JAMES Ereporter.nih.gov
Wyoming Sensory Biology COBRENIHNational Institute of General Medical Sciences2021 to 2025$13,747,906September 1, 2017July 31, 2027SUN, QIAN-QUANreporter.nih.gov
Arylepoxamides: A new class of potent, safer analgesicsNIHNational Institute on Drug Abuse2021 to 2023$13,729,307December 15, 2018August 31, 2025REICH, JEFFREYreporter.nih.gov
Admin. Supp.: Correction of Neurological Disease via Allele Specific Excision of Pathogenic RepeatsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$13,703,967May 15, 2023April 30, 2028DOUDNA, JENNIFER Areporter.nih.gov
1/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U UTAHNIHNational Institute on Drug Abuse2021 to 2025$13,649,176September 30, 2015March 31, 2027YURGELUN-TODD, DEBORAH A.reporter.nih.gov
A Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Phase II Study to Evaluate the Safety and Efficacy of CT1812 in Subjects with Mild to Moderate Alzheimerʼs DiseaseNIHNational Institute on Aging2021$13,634,548September 15, 2018May 31, 2024CAGGIANO, ANTHONY Oreporter.nih.gov
Center for the Study of Aphasia Recovery (C-STAR)NIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$13,541,079April 1, 2016March 31, 2027FRIDRIKSSON, JULIUSreporter.nih.gov
Lysosome Regulation and Signaling in Aging and Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$13,495,371June 1, 2021February 28, 2027ZHENG, HUIreporter.nih.gov
1/2 ICECAP: Influence of Cooling duration on Efficacy in Cardiac Arrest PatientsNIHNational Heart, Lung, and Blood Institute2021 to 2024$13,466,840September 19, 2019August 31, 2025MEURER, WILLIAM JOSEPHreporter.nih.gov
1Florida Alzheimer's Disease Research CenterNIHNational Institute on Aging2021 to 2025$13,348,245June 15, 2020April 30, 2027SMITH, GLENN E.reporter.nih.gov
Epidemiological and Genetic Investigations of Blood-Based Biomarkers for Alzheimer's Disease in the Multiethnic, Washington Heights, Inwood, Columbia Aging Project (WHICAP)NIHNational Institute on Aging2021 to 2025$13,310,071June 1, 2021March 31, 2027MAYEUX, RICHARD Preporter.nih.gov
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028NIHNational Heart, Lung, and Blood Institute2024 to 2025$13,305,831July 7, 2010March 31, 2029CORESH, JOSEFreporter.nih.gov
Prevention of Fractures in Patients with Parkinson's DiseaseNIHNational Institute on Aging2022 to 2024$13,269,734September 30, 2018February 28, 2026CUMMINGS, STEVEN RONreporter.nih.gov
TO4. CLINICAL COORDINATING CENTER FOR NIDA'S CLINICAL TRIALS NETWORK. CONTRACT TYPE: IDIQ TASK ORDER. POP: 8/15/24 - 8/14/29NIHNational Institute on Drug Abuse2024 to 2025$13,234,516July 16, 2025July 15, 2026reporter.nih.gov
BRAIN CONNECTS: The center for Large-scale Imaging of Neural Circuits (LINC)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$13,208,545September 1, 2023June 30, 2028YENDIKI, ANASTASIAreporter.nih.gov
MIND DIET AND DEMENTIA PREVENTION IN ISCHEMIC STROKE PATIENTSNIHNational Institute on Aging2021 to 2025$13,186,351September 1, 2020May 31, 2027AGGARWAL, NEELUM T.reporter.nih.gov
Harmonized Diagnostic Assessment of Dementia (DAD) for Longitudinal Aging Surveys in India (LASI)NIHNational Institute on Aging2021 to 2025$13,167,007September 15, 2015April 30, 2026LEE, JINKOOKreporter.nih.gov
Study in Parkinson Disease of Exercise Phase 3 Clinical Trial: SPARX3NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$13,006,073September 25, 2019July 31, 2026CORCOS, DANIEL M.reporter.nih.gov
Plasma brain-derived tau: a novel Alzheimer’s disease-type neurodegeneration biomarker with potential to complete the AT(N) scheme in bloodNIHNational Institute on Aging2023 to 2025$12,972,426September 1, 2023May 31, 2028KARIKARI, THOMAS Kreporter.nih.gov
The A3 Study: Ante-Amyloid Prevention of Alzheimer's diseaseNIHNational Institute on Aging2021 to 2023$12,937,549August 15, 2016April 30, 2024SPERLING, REISA A.reporter.nih.gov
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research CentersNIHNational Institute on Drug Abuse2021 to 2025$12,902,047September 30, 2021July 31, 2026BECKER, WILLIAM Creporter.nih.gov
HEALTH Center for Addictions Research and Cancer PreventionNIHNational Institute on Minority Health and Health Disparities2021 to 2024$12,882,144September 8, 2020April 30, 2026BEECH, BETTINA M.reporter.nih.gov
Supporting Treatment Access and Recovery for Co-Occurring Opioid Use and Mental Health Disorders (STAR-COD)NIHNational Institute of Mental Health2021 to 2024$12,719,359September 16, 2021August 31, 2025SMELSON, DAVID Areporter.nih.gov
THE NIH NEUROBIOBANK AND TISSUE REPOSITORYNIHNational Institute on Drug Abuse2021 to 2025$12,702,242May 1, 2025October 31, 2025BLANCHARD, THOMASreporter.nih.gov
Testing Hypothesized Pathways Linking Infection, Physical Activity, Apoe Genotype, And Biological Sex To Low Dementia Prevalence And Reduced Brain Atrophy In Two Native American PopulationsNIHNational Institute on Aging2022 to 2025$12,690,286April 15, 2017April 30, 2027KAPLAN, HILLARD Sreporter.nih.gov
Clinical Trial Data Processing, Analysis, and Coordination Center (CT-DPACC) for Accelerating Medicines Partnership Schizophrenia (AMP SCZ) ProjectNIHNational Institute of Mental Health2024 to 2025$12,671,179June 17, 2024May 31, 2029SHENTON, MARTHA E.reporter.nih.gov
Tailored Retention and Engagement for Effective integrated Treatment of OUD and Pain (TREETOP)NIHNational Institute on Drug Abuse2021 to 2025$12,656,947September 30, 2021July 31, 2027WINSTANLEY, ERIN Lreporter.nih.gov
Medicare at a CrossroadsNIHNational Institute on Aging2021 to 2025$12,593,170August 15, 2009April 30, 2030LANDON, BRUCE E.reporter.nih.gov
A Randomized, Double-Blind, Placebo-Controlled Study of LHP588 in Subjects with P. gingivalis-Positive Alzheimer's DiseaseNIHNational Institute on Aging2025$12,591,952August 15, 2025July 31, 2029DETKE, MICHAEL J.reporter.nih.gov
Phase 2 Randomized, Double-Blind, Placebo-Controlled Clinical Trial of T3D-959 in Mild to Moderate Alzheimer's Disease SubjectsNIHNational Institute on Aging2021 to 2022$12,573,346May 1, 2019February 28, 2023DIDSBURY, JOHNreporter.nih.gov
Single Cell Transcriptomic and Epigenomic Dissection of Opioid and Cocaine Responses in HIVNIHNational Institute on Drug Abuse2021 to 2025$12,564,620September 1, 2021June 30, 2027KELLIS, MANOLISreporter.nih.gov
Duke Autism Center of Excellence: A translational digital health and computational approach to early identification, outcome monitoring, and biomarker discovery in autismNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$12,545,063September 7, 2017August 31, 2027DAWSON, GERALDINEreporter.nih.gov
Investigating regional and cellular vulnerabilities to tau pathology in young-onset Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$12,536,106February 15, 2022November 30, 2026MURRAY, MELISSA ERINreporter.nih.gov
Endophenotypes of Persistent Post-Concussive Symptoms in Adolescents: CARE4KidsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$12,522,070September 8, 2021March 31, 2027GIZA, CHRISTOPHER Creporter.nih.gov
Center for Addiction and Disease Risk ExacerbationNIHNational Institute of General Medical Sciences2021 to 2025$12,487,946August 1, 2019July 31, 2029MONTI, PETER M.reporter.nih.gov
Impacts of receiving Alzheimer's disease genetic risk information among Latinos in northern ManhattanNIHNational Institute on Aging2021 to 2024$12,295,034February 15, 2020November 30, 2025OTTMAN, RUTHreporter.nih.gov
Autism Center of Excellence Network: Neurodevelopmental Biomarkers of Late Diagnosis in AutismNIHNational Institute of Mental Health2021 to 2025$12,178,377September 4, 2012June 30, 2027PELPHREY, KEVIN Areporter.nih.gov
Exploring Cognitive Aging Using Reference Ability Neural NetworksNIHNational Institute on Aging2021 to 2025$12,167,937September 1, 2011June 30, 2027STERN, YAAKOVreporter.nih.gov
StrokeNet Thrombectomy Endovascular Platform (STEP)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$12,112,868September 1, 2022February 28, 2026ELM, JORDAN J.reporter.nih.gov
Center for Research and Education on Aging and Technology Enhancement - CREATENIHNational Institute on Aging2022 to 2025$12,069,399June 15, 2022May 31, 2027CZAJA, SARA Jreporter.nih.gov
Advancing brain health research through male germline editing in marmosetsNIHNational Institute on Drug Abuse2021 to 2025$12,061,296August 1, 2021May 31, 2027HERMANN, BRIAN PETERreporter.nih.gov
Center for Live Cell GenomicsNIHNational Human Genome Research Institute2021 to 2025$11,992,289September 15, 2021June 30, 2027HAUSSLER, DAVID Hreporter.nih.gov
Alzheimers Disease Patient Registry (Administrative Supplement)NIHNational Institute on Aging2021 to 2023$11,991,901September 30, 1986June 30, 2026PETERSEN, RONALD Creporter.nih.gov
A Placebo-Controlled Effectiveness in INPH Shunting (PENS) TrialNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$11,962,900September 30, 2021July 31, 2027LUCIANO, MARK GREGORYreporter.nih.gov
DIAN-TU: Next Generation Prevention TrialNIHNational Institute on Aging2022 to 2023$11,960,034September 1, 2017May 31, 2024BATEMAN, RANDALL Jreporter.nih.gov
Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems.NIHNational Institute on Aging2021 to 2025$11,898,685September 15, 2007May 31, 2029TRIVEDI, AMAL N.reporter.nih.gov
I3C DECADE: Developmental Epidemiology of Childhood Cardiovascular Exposures and Alzheimer’s DementiaNIHNational Institute on Aging2022 to 2025$11,889,015July 1, 2022April 30, 2028MACLEHOSE, RICHARD Freporter.nih.gov
Scalable Expanded Access with Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS (SEA-NOBI-ALS)NIHNational Institute of Neurological Disorders and Stroke2024 to 2025$11,846,278September 1, 2024August 31, 2028OSKARSSON, BJORN Ereporter.nih.gov
REVERSE-Long COVID: A Multicenter Randomized, Placebo-Controlled Clinical Trial of Immunomodulation (with Baricitinib) for Long COVID Related ADRDNIHNational Institute on Aging2024 to 2025$11,773,020January 1, 2024December 31, 2028ELY, E WESLEYreporter.nih.gov
COBRE Center on Opioids and OverdoseNIHNational Institute of General Medical Sciences2021 to 2025$11,768,169September 1, 2018August 31, 2028RICH, JOSIAH Dreporter.nih.gov
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate IntoxicationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$11,668,134September 1, 2022August 31, 2027LEIN, PAMELA Jreporter.nih.gov
Cross Sectional and Longitudinal Racial Disparity in Molecular Biomarkers of Alzheimer DiseaseNIHNational Institute on Aging2021 to 2024$11,652,217June 1, 2020March 31, 2026XIONG, CHENGJIEreporter.nih.gov
Intermediate-sized Expanded Access Protocol for CNM-Au8 in Amyotrophic Lateral Sclerosis (ALS).NIHNational Institute of Neurological Disorders and Stroke2025$11,639,047September 25, 2023August 31, 2027ANDREWS, JINSYreporter.nih.gov
Cancer Center Support (CORE) GrantNIHNational Cancer Institute2021 to 2025$11,628,123August 1, 1997June 30, 2030PALUCKA, ANNA KAROLINAreporter.nih.gov
West Virginia University Stroke COBRENIHNational Institute of General Medical Sciences2021 to 2024$11,604,264September 8, 2014May 31, 2026DEVRIES, ANNE COURTNEYreporter.nih.gov
Early Life Adversity, Biological Embedding, and Risk for Developmental Precursors of Mental DisordersNIHNational Institute of Mental Health2021 to 2025$11,595,410May 22, 2018May 31, 2028LUBY, JOAN L.reporter.nih.gov
Kynurenine accumulation drives loss of muscle and bone function with agingNIHNational Institute on Aging2021 to 2025$11,563,609May 1, 2011May 31, 2027ISALES, CARLOS M.reporter.nih.gov
Estrogens, Cardiometabolic Health, and Female Cognitive AgingNIHNational Institute on Aging2022 to 2025$11,521,268March 1, 2022February 28, 2027DANIEL, JILL Mreporter.nih.gov
Mapping Cellular Resolution Connectopathies in Aging and Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$11,497,463May 15, 2022April 30, 2027DONG, HONG-WEIreporter.nih.gov
Sleep in Neurocognitive Aging and Alzheimers Research (SANAR)NIHNational Institute on Aging2021 to 2025$11,494,462February 1, 2021January 31, 2027RAMOS, ALBERTO RAFAELreporter.nih.gov
Impact of Neuroinflammation on AD Occurrence: A Bi-Generational Population StudyNIHNational Institute on Aging2021 to 2025$11,418,675September 1, 2021May 31, 2027RAJAN, KUMAR B.reporter.nih.gov
Genomic Characterization of Alzheimer Disease Risk in Admixed Populations with Native American and Southern European Genetic AncestryNIHNational Institute on Aging2021 to 2025$11,411,820February 1, 2021January 31, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
A Longitudinal Brain and Behavior Study of Autism From Infancy Through AdolescenceNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$11,410,066July 1, 2007August 31, 2027PIVEN, JOSEPHreporter.nih.gov
Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$11,402,108September 30, 2004May 31, 2027BARNES, LISA Lreporter.nih.gov
Supplement to TR01 Human cortical development and neural plasticity altered by trisomy 21NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$11,380,369September 10, 2021August 31, 2027BHATTACHARYYA, ANITAreporter.nih.gov
Complement Mediated Remodeling in Pulmonary Vascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$11,355,302August 1, 2020June 30, 2026STENMARK, KURT R.reporter.nih.gov
Remote Monitoring and Virtual Collaborative Care for Hypertension Control to Prevent Cognitive DeclineNIHNational Institute on Aging2021 to 2024$11,354,079August 1, 2020July 31, 2025GUPTA, ADITIreporter.nih.gov
Circuit-specific cell types in aging and Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$11,340,010June 1, 2022May 31, 2028LEE, KUO-FENreporter.nih.gov
Whole Genome Sequencing and Admixture Analyses of Neuropathologic Traits in Diverse Cohorts in USA and BrazilNIHNational Institute on Aging2023 to 2025$11,334,713August 15, 2023July 31, 2028BENNETT, DAVID ALANreporter.nih.gov
Pre-Symptomatic Familial ALS (Pre-fALS) Study: From Prodrome and Biomarkers to ALS/FTD PreventionNIHNational Institute of Neurological Disorders and Stroke2025$11,282,768September 15, 2018July 31, 2029BENATAR, MICHAELreporter.nih.gov
Center for Dissemination and Implementation At Stanford (C-DIAS)NIHNational Institute on Drug Abuse2022 to 2025$11,245,029August 1, 2022May 31, 2027MCGOVERN, MARK Preporter.nih.gov
The Longitudinal Course of Imaging Biomarkers in People At Risk for Alzheimer’s DiseaseNIHNational Institute on Aging2022 to 2025$11,223,576August 15, 2004March 31, 2027JOHNSON, STERLING Creporter.nih.gov
KBASE2: Korean Brain Aging Study, Longitudinal Endophenotypes and Systems BiologyNIHNational Institute on Aging2021 to 2025$11,202,386August 15, 2021July 31, 2027SAYKIN, ANDREW Jreporter.nih.gov
Revealing the single cell determinants of brain relevant to persistent HIV infection and opioid use disorderNIHNational Institute on Drug Abuse2021 to 2025$11,197,081September 30, 2021July 31, 2027RANA, TARIQ Mreporter.nih.gov
Site-Directed RNA Editing of Nav1.7 as a Novel AnalgesicNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$11,194,636September 23, 2021August 31, 2027ROSENTHAL, JOSHUA J.C.reporter.nih.gov
1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African AncestriesNIHNational Institute of Mental Health2021 to 2024$11,112,946September 14, 2020July 31, 2025NEALE, BENJAMIN MICHAELreporter.nih.gov
Single cell brain transcriptome changes during chronic HIV infection and opiate use in conventional miceNIHNational Institute on Drug Abuse2021 to 2025$11,085,606May 15, 2021July 31, 2026KENNY, PAUL J.reporter.nih.gov
Center for Neural Circuits in AddictionNIHNational Institute on Drug Abuse2021 to 2025$10,925,897August 15, 2020May 31, 2030THOMAS, MARK JOHNreporter.nih.gov
Cell-type-specific neural circuit connectomes in the mouse models of aging and Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$10,898,840May 15, 2022April 30, 2027XU, XIANGMINreporter.nih.gov
A Seamless Phase 2A-B Randomized Double Blind Placebo Controlled Trial to Evaluate the Efficacy and Safety of PQ 912 in Patients with Early Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2023$10,874,349April 1, 2019June 30, 2025FELDMAN, HOWARDreporter.nih.gov
Center to Advance Research Excellence (OPTIC)NIHNational Institute on Drug Abuse2021 to 2025$10,836,251August 15, 2018June 30, 2028STEIN, BRADLEY Dreporter.nih.gov
5/21 ABCD-USA Consortium: Research Project Site at UC San DiegoNIHNational Institute on Drug Abuse2021 to 2025$10,821,558September 30, 2015March 31, 2027TAPERT, SUSAN F.reporter.nih.gov
Longitudinal Imaging Biomarkers of Prodromal DLBNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$10,821,041September 25, 2017August 31, 2027KANTARCI, KEJALreporter.nih.gov
Scientific Management and Support to the National Institute of Mental Health (NIMH) Repository and Genomics Resource (NRGR)NIHNational Institute on Drug Abuse2025$10,685,838August 11, 2025August 10, 2026reporter.nih.gov
Greater Intermountain Node (CTN-0138)NIHNational Institute on Drug Abuse2021 to 2025$10,595,733March 1, 2025February 29, 2032COCHRAN, GERALD T.reporter.nih.gov
Blood amyloid, tau, and neurodegeneration biomarkers and prediction of clinical onset, cognitive decline, and dementia diagnosisNIHNational Institute on Aging2024 to 2025$10,584,728September 30, 2008May 31, 2029BATEMAN, RANDALL Jreporter.nih.gov
Arterial Stiffness, Cognition, and Equol (ACE)NIHNational Institute on Aging2022 to 2025$10,581,052February 15, 2022January 31, 2027SEKIKAWA, AKIRAreporter.nih.gov
Addressing risk through Community Treatment for Infectious disease and Opioid use disorder Now (ACTION) among justice-involved populationsNIHNational Institute on Drug Abuse2021 to 2025$10,550,278September 30, 2020July 31, 2026SPRINGER, SANDRA ANNreporter.nih.gov
VCID Biomarkers Coordinating CenterNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$10,493,954September 30, 2016June 30, 2027GREENBERG, STEVEN Mreporter.nih.gov
The INCLUDE Project Down Syndrome Biorepository (DS-Biorepository)NIHNational Institute on Aging2024 to 2025$10,436,444September 30, 2024August 31, 2029ESPINOSA, JOAQUIN M.reporter.nih.gov
Mount Sinai ECHO site for Perinatal Environment and Development StudiesNIHOffice of the Director, National Institutes of Health2023 to 2024$10,423,916September 21, 2016May 31, 2025WRIGHT, ROSALIND Jreporter.nih.gov
SPORE in Brain CancerNIHNational Cancer Institute2021 to 2025$10,413,880September 1, 2008August 31, 2029LANG, FREDERICK Freporter.nih.gov
Growth and development of Striatal-Cerebellum circuitry in subjects at risk for Huntington’s DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$10,413,314March 1, 2009August 31, 2026NOPOULOS, PEGGY Creporter.nih.gov
NIH StrokeNet National Clinical Coordinating Center (NCC)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$10,366,158September 30, 2013November 30, 2028BRODERICK, JOSEPH PAULreporter.nih.gov
Safety/Tolerability/Immunogenicity of first-in-human Aβ DNA vaccine, AV-1959D Phase 1 trials in early-stage AD subjects: based on IND18953 cleared by FDA.NIHNational Institute on Aging2022 to 2025$10,320,460February 15, 2022January 31, 2027AGADJANYAN, MICHAEL Greporter.nih.gov
BRAIN-ICU-2 Study: Bringing to Light the Risk Factors And Incidence of Neuropsychological Dysfunction (Dementia) in ICU Survivors, 2nd StudyNIHNational Institute on Aging2021 to 2024$10,318,677April 15, 2019January 31, 2026ELY, E WESLEYreporter.nih.gov
9/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MICHIGANNIHNational Institute on Drug Abuse2021 to 2025$10,318,458September 30, 2015March 31, 2027HEITZEG, MARY Mreporter.nih.gov
Cannabidiol in the treatment of opioid use disorderNIHNational Institute on Drug Abuse2024$10,316,590September 30, 2019August 31, 2027HURD, YASMIN L.reporter.nih.gov
15/21 ABCD-USA Consortium: Research Project Site at LIBRNIHNational Institute on Drug Abuse2021 to 2025$10,302,955April 15, 2020March 31, 2027PAULUS, MARTIN P.reporter.nih.gov
Validation of Early Prognostic Data for Recovery Outcomes after Stroke for Future, Higher Yield Trials (VERIFY)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$10,302,336September 1, 2021July 1, 2025KHATRI, POOJAreporter.nih.gov
Alzheimer's Disease and Related Dementias (ADRD) prevalence in American SamoaNIHNational Institute on Aging2022 to 2025$10,293,481September 30, 2022August 31, 2027TOFAEONO, VAATAUSILI Treporter.nih.gov
NIH Health Care Systems Research Collaboratory-Coordinating Center (U24)NIHNational Center for Complementary & Integrative Health2021 to 2025$10,249,994September 22, 2022May 31, 2028HERNANDEZ, ADRIANreporter.nih.gov
Vermont Center for Cardiovascular and Brain HealthNIHNational Institute of General Medical Sciences2021 to 2024$10,185,844August 6, 2020May 31, 2026CUSHMAN, MARYreporter.nih.gov
ACTIVE MIND: An adaptive clinical trial of cognitive training to improve function and delay dementiaNIHNational Institute on Aging2022 to 2023$10,112,651September 1, 2022June 24, 2024O'BRIEN, JENNIFER LEEreporter.nih.gov
StATins Use in intRacerebral hemorrhage patieNts (SATURN)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$10,035,219September 1, 2019February 29, 2028SELIM, MAGDY Hreporter.nih.gov
4/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT FIUNIHNational Institute on Drug Abuse2021 to 2025$9,979,334September 30, 2015March 31, 2027GONZALEZ, RAULreporter.nih.gov
NEUROBIOBANK BRAIN AND TISSUE REPOSITORYNIHNational Institute on Drug Abuse2021 to 2025$9,962,676May 1, 2025October 31, 2025LEWIS, DAVIDreporter.nih.gov
Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators and SusceptibilityNIHNational Institute on Aging2021 to 2024$9,901,034May 1, 2021February 28, 2026REDLINE, SUSAN S.reporter.nih.gov
Life’s end Benefits of CannaBidol and TetrahYdrocannabinol (LiBBY) TrialNIHNational Institute on Aging2021 to 2022$9,892,823September 15, 2020April 30, 2026MINTZER, JACOBOreporter.nih.gov
Gateway Exposome Coordinating Center (GECC) For AD/ADRD ResearchNIHNational Institute on Aging2024 to 2025$9,887,007August 1, 2024July 31, 2029LEE, JINKOOKreporter.nih.gov
PF614-MPAR: clinical development of opioid with oral overdose protectionNIHNational Institute on Drug Abuse2024 to 2025$9,861,616September 1, 2024May 31, 2027KIRKPATRICK, LYNNreporter.nih.gov
Autism Genetics Phase II: Increasing Representation of Human DiversityNIHNational Institute of Mental Health2021 to 2024$9,859,913March 25, 2013May 31, 2028GESCHWIND, DANIEL Hreporter.nih.gov
Silence ALS: A Platform for the Discovery and Development of Antisense Therapeutics for Patients with Ultra-Rare Forms of ALSNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$9,796,602March 1, 2024February 28, 2027SHNEIDER, NEIL ALANreporter.nih.gov
21/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT WUSTLNIHNational Institute on Drug Abuse2021 to 2025$9,776,479April 15, 2020March 31, 2027MADDEN, PAMELA ANNreporter.nih.gov
Sickle Cell Disease and Cardiovascular Risk- Red Cell Exchange SCD-CARRENIHNational Heart, Lung, and Blood Institute2022 to 2025$9,739,425September 1, 2022April 30, 2027GLADWIN, MARK Treporter.nih.gov
Thalamocortical Responsive Neurostimulation for the Treatment of Lennox-Gastaut SyndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,737,772June 1, 2021May 31, 2027MORRELL, MARTHA Jreporter.nih.gov
Select Late-Stage CMC, Non-clinical Studies, and Quality Programs to Accelerate NRS-033 Towards Pivotal Studies and Registration in Opioid Use DisorderNIHNational Institute on Drug Abuse2024 to 2025$9,732,775August 1, 2024May 31, 2027SHAH, NIKEJreporter.nih.gov
Vanderbilt Diabetes Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$9,726,538December 1, 1996March 31, 2027POWERS, ALVIN Creporter.nih.gov
DEploying High ValuE LOngitudinal Population-Based dAta in Dementia Research (DEVELOP AD Research)NIHNational Institute on Aging2021 to 2024$9,684,597September 30, 2020May 31, 2026MORRISON, R. SEANreporter.nih.gov
Study to Uncover Pathways to Exceptional Cognitive Resilience in Aging (SUPERAging)NIHNational Institute on Aging2023 to 2025$9,673,461September 30, 2021August 31, 2027ROGALSKI, EMILY Jreporter.nih.gov
National Swine Resource and Research Center (NSRRC) Years 21-25NIHOffice of the Director, National Institutes of Health2021 to 2025$9,635,041September 1, 2003July 31, 2028LEE, KIHOreporter.nih.gov
TASK ORDER 1 - OCR PROJECT MANAGEMENT, DSMB AND CROMS-RELATED SUPPORTNIHNational Institute on Drug Abuse2024 to 2025$9,613,167March 25, 2024March 24, 2026APPELMANS, ELINEreporter.nih.gov
Collaborative Approach for Asian Americans, Native Hawaiians, and Pacific Islanders Research and Education (CARE) 2.0NIHNational Institute on Aging2023 to 2025$9,607,843August 1, 2023June 30, 2028PARK, VAN MY TAreporter.nih.gov
Southern Consortium Node of the Clinical Trials Network (TMS for CUD)NIHNational Institute on Drug Abuse2021 to 2025$9,579,585March 1, 2025February 29, 2032BARTH, KELLY S.reporter.nih.gov
M-SCORCH: Methamphetamine use disorder data generation center for Single Cell Opioid Responses in the Context of HIVNIHNational Institute on Drug Abuse2021 to 2025$9,490,616May 15, 2021February 28, 2027HO, YA-CHIreporter.nih.gov
CNS Effects of Alcohol: Cellular NeurobiologyNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$9,489,642December 1, 1983December 31, 2027ROBERTO, MARISAreporter.nih.gov
Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid and Tau in Older Adults (IPAT-study)NIHNational Institute on Aging2022 to 2025$9,488,371August 1, 2022July 31, 2027ZHANG, RONGreporter.nih.gov
Thin, High-Density, High-Performance, Depth and Surface Microelectrodes for Diagnosis and Treatment of EpilepsyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,482,559September 1, 2021August 31, 2027DAYEH, SHADIreporter.nih.gov
BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a TrialNIHNational Institute on Aging2021 to 2025$9,481,336February 15, 2021November 30, 2026HANLEY, DANIEL Freporter.nih.gov
Effects of Successful OSA TreatmENT on Memory and AD BIomarkers in Older AduLts (ESSENTIAL)NIHNational Institute on Aging2025$9,466,491September 1, 2023August 31, 2028STONE, KATIE Lreporter.nih.gov
Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE)NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$9,464,743February 1, 2019January 31, 2026RAMEY, SHARON LANDESMANreporter.nih.gov
Prospective Genetic Risk Evaluation and Assessment (PROGRESS) in AutismNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$9,460,610September 6, 2022August 31, 2027VEENSTRA-VANDERWEELE, JEREMYreporter.nih.gov
1/3 Genomics of Schizophrenia in the South African XhosaNIHNational Institute of Mental Health2021 to 2025$9,460,283January 1, 2021December 31, 2026KING, MARY-CLAIREreporter.nih.gov
2/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UMBNIHNational Institute on Drug Abuse2021 to 2025$9,449,174September 30, 2015March 31, 2027ERNST, THOMAS Mreporter.nih.gov
Tulane COBRE for Clinical and Translational Research in Cardiometabolic DiseasesNIHNational Institute of General Medical Sciences2022 to 2025$9,439,774March 10, 2016June 30, 2027MILLS, KATHERINE TERESAreporter.nih.gov
Uncovering the Genetic Mechanisms of the Chromosome 17q21.31 Tau Haplotype on Neurodegeneration Risk in FTD and PSPNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,418,230September 1, 2021August 31, 2026GOATE, ALISON Mreporter.nih.gov
TO ADMINISTRATIVELY DE-OBLIGATE UNEXPENDED AND EXPIRING FISCAL YEAR 2020 FUNDING IN ACCORDANCE WITH 31 U.S.C. SECTION 1552 (A), IN PREPARATION FOR SEPTEMBER 30, 2025, CLOSING OF THE PERIOD OF AVAILABINIHOffice of the Director, National Institutes of Health2021 to 2025$9,377,344May 1, 2025October 31, 2025reporter.nih.gov
Genetic Epidemiology and Multi-Omics Analyses in Familial and Sporadic Alzheimer's Disease Among Secular Caribbean Hispanics and Religious OrderNIHNational Institute on Aging2021 to 2024$9,373,073June 1, 2020March 31, 2026MAYEUX, RICHARD Preporter.nih.gov
A novel therapeutic to ameliorate chronic pain and reduce opiate useNIHNational Institute on Drug Abuse2021 to 2024$9,323,255March 15, 2019June 30, 2024TABAKOFF, BORISreporter.nih.gov
Ketamine Add-On for Established Status Epilepticus Treatment Trial (KESETT)NIHNational Institute of Neurological Disorders and Stroke2025$9,296,510January 15, 2025December 31, 2026KAPUR, JAIDEEPreporter.nih.gov
The San Antonio Heart and Mind StudyNIHNational Institute on Aging2023 to 2025$9,286,743July 1, 2023March 31, 2029SATIZABAL, CLAUDIA Lreporter.nih.gov
African Americans Fighting Alzheimer’s in Midlife (AA-FAIM)NIHNational Institute on Aging2021 to 2025$9,250,399August 1, 2016November 30, 2027GLEASON, CAREY Ereporter.nih.gov
Assessing the role of cerebrovascular brain injury and dysfunction in Alzheimer’s disease pathogenesis in the BEACoN CohortNIHNational Institute on Aging2021 to 2025$9,240,061August 1, 2017December 31, 2027YASSA, MICHAEL Areporter.nih.gov
Development of a novel drug for treating opioid use disorderNIHNational Institute on Drug Abuse2022 to 2024$9,160,866March 15, 2019August 31, 2025SHAH, NIKEJreporter.nih.gov
The Care Ecosystem Response to COVID-19: Accelerating Research on Dementia Care that Meets the Needs of Caregivers and Persons with Dementia during COVID-19NIHNational Institute on Aging2022 to 2024$9,143,854June 15, 2022May 31, 2026POSSIN, KATHERINE LAURELreporter.nih.gov
HIV Center for Clinical and Behavioral StudiesNIHNational Institute of Mental Health2021 to 2025$9,131,244September 30, 1987April 30, 2028REMIEN, ROBERT Hreporter.nih.gov
GEARs Combining advances in Genomics and Environmental science to accelerate Actionable Research and practice in ASDNIHNational Institute of Environmental Health Sciences2022 to 2025$9,120,320September 6, 2022August 31, 2027VOLK, HEATHER Ereporter.nih.gov
Anticoagulation in ICH Survivors for Prevention and Recovery (ASPIRE)NIHNational Institute of Neurological Disorders and Stroke2023 to 2024$9,111,057July 1, 2019April 30, 2027SHETH, KEVIN NAVINreporter.nih.gov
Identification of TDP-43 Modifiers Through Single-Cell Transcriptional and Epigenomic Dissection of ALS and FTLD-MNDNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,106,321September 29, 2021August 31, 2026DONNELLY, CHRISTOPHER JAMESreporter.nih.gov
Center of Excellence in Environmental ToxicologyNIHNational Institute of Environmental Health Sciences2021 to 2025$9,096,433April 1, 2006May 31, 2030PENNING, TREVOR Mreporter.nih.gov
Resilience and brain health of older adultsNIHNational Institute on Aging2021 to 2025$9,066,206August 15, 2021May 31, 2027LENZE, ERIC Jreporter.nih.gov
University of New Mexico (UNM) Center for Brain Recovery and RepairNIHNational Institute of General Medical Sciences2021 to 2024$9,061,444September 15, 2015June 30, 2026SHUTTLEWORTH, CLAUDE Wreporter.nih.gov
Fragmented early-life experiences, aberrant circuit maturation, emotional vulnerabilitiesNIHNational Institute of Mental Health2021 to 2023$9,060,652June 17, 2013March 31, 2025BARAM, TALLIE Z.reporter.nih.gov
Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in SmokersNIHNational Institute on Drug Abuse2023 to 2025$9,048,057September 30, 2023August 31, 2026COSFORD, NICHOLAS DAVIDreporter.nih.gov
NATIONAL NEUROHIV TISSUE CONSORTIUM (NNTC) - CLINICAL SITE - Alzheimer's diseaseNIHNational Institute of Mental Health2023 to 2025$9,005,480August 23, 2023August 22, 2026HADIJAH, VACTORreporter.nih.gov
Epidemiologic Study of Neural Reserve and Neurobiology of AgingNIHNational Institute on Aging2021 to 2023$8,995,869September 30, 2001May 31, 2026BENNETT, DAVID ALANreporter.nih.gov
Center for Stress and Neural Regulation of Reproductive Aging Health OutcomesNIHNational Institute on Aging2021 to 2025$8,986,759June 1, 2020August 31, 2030JOFFE, HADINEreporter.nih.gov
Prevention Research Center: Parenting Among Women Who Are Opioid UsersNIHNational Institute on Drug Abuse2021 to 2023$8,972,150August 15, 2019May 31, 2025LEVE, LESLIE DIANEreporter.nih.gov
TO AWARD THE BASE PERIOD FOR NIMH PSYCHOACTIVE DRUG SCREENING PROGRAM (PDSP). BASE POP: 08/30/2023-08/29/2024.NIHNational Institute on Drug Abuse2023 to 2025$8,957,809August 30, 2023August 29, 2026ROTH, BRYANreporter.nih.gov
Identifying the genetic causes of depression in a deeply phenotyped population from South KoreaNIHNational Institute of Mental Health2021 to 2025$8,898,757August 17, 2021June 30, 2027FLINT, JONATHANreporter.nih.gov
Consequences of Incarceration on Health, Age-Related Conditions, and Risk Factors for ADRDNIHNational Institute on Aging2024 to 2025$8,887,003August 15, 2024April 30, 2029TEPLIN, LINDA Areporter.nih.gov
Molecular and Circuit Pathogenesis of Alcohol Use DisordersNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$8,884,347December 1, 1997November 30, 2027KASH, THOMAS L.reporter.nih.gov
Biospecimen Exchange for Neurological Disorders (BioSEND)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$8,861,360August 1, 2021July 31, 2027FOROUD, TATIANA M.reporter.nih.gov
Center for Genetic Studies of Drug Abuse in Outbred RatsNIHNational Institute on Drug Abuse2021 to 2023$8,856,132June 15, 2014April 30, 2025PALMER, ABRAHAM Areporter.nih.gov
Johns Hopkins-Tufts Trial Innovation Center HEAL Pain ERN SupplementNIHNational Center for Advancing Translational Sciences2021 to 2022$8,842,412July 1, 2016June 30, 2023HANLEY, DANIEL Freporter.nih.gov
Translational Platform for Epilepsy Therapy and Biomarker DiscoveryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$8,833,081April 15, 2022March 31, 2027GALANOPOULOU, ARISTEA Sreporter.nih.gov
7/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT YALENIHNational Institute on Drug Abuse2021 to 2025$8,739,227September 30, 2015March 31, 2027BASKIN-SOMMERS, ARIELLE RYANreporter.nih.gov
Multiscale functional characterization of genomic variation in human developmental disordersNIHNational Human Genome Research Institute2021 to 2025$8,736,987September 1, 2021May 31, 2027HON, GARY CHUNGreporter.nih.gov
Risk Factors, Pathology, and Clinical Expressions of ADNIHNational Institute on Aging2021 to 2024$8,703,055July 15, 1998April 30, 2026BENNETT, DAVID ALANreporter.nih.gov
Health Economics of Substance Use Disorder, HCV, and HIV Treatment: Supporting Financial Sustainability, Advanced Methods, and Knowledge TranslationNIHNational Institute on Drug Abuse2021 to 2025$8,690,640July 15, 2015April 30, 2030SCHACKMAN, BRUCE Rreporter.nih.gov
Development of PPL-138, a Novel Mixed NOP/Mu Partial Agonist for Treatment of CocaineUse DisorderNIHNational Institute on Drug Abuse2022 to 2024$8,683,509September 30, 2022July 31, 2025TOLL, LAWRENCE Rreporter.nih.gov
19/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UVMNIHNational Institute on Drug Abuse2021 to 2025$8,669,646April 15, 2020March 31, 2027GARAVAN, HUGH P.reporter.nih.gov
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular InteractionsNIHNational Institute on Aging2021 to 2025$8,654,669July 1, 2021June 30, 2027TEMPLE, SALLYreporter.nih.gov
Public Health and Autism Science advancing Effectual Strategies across the life course (PHASES)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$8,623,178September 6, 2022August 31, 2027ROBINS, DIANA Lreporter.nih.gov
Revisiting ReCHARGE: ECHO Follow up on Middle Childhood and AdolescenceNIHOffice of the Director, National Institutes of Health2021 to 2025$8,577,337September 21, 2016May 31, 2030HERTZ-PICCIOTTO, IRVAreporter.nih.gov
TCN PATHS Supplemental fundingNIHNational Institute on Drug Abuse2021 to 2024$8,572,442July 15, 2019April 30, 2026WANG, EMILY AI-HUAreporter.nih.gov
Educational and Early Life Predictors of Mild Cognitive Impairment: New Evidence about Mediators and Moderators from High School & BeyondNIHNational Institute on Aging2023 to 2024$8,554,832May 15, 2019February 28, 2026WARREN, JOHN ROBERTreporter.nih.gov
P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in IndiaNIHNational Institute on Aging2024 to 2025$8,548,820September 15, 2024August 31, 2029NARAYAN, KABAYAM M VENKATreporter.nih.gov
Alzheimer variants: Propagation of shared functional changes across cellular networksNIHNational Institute on Aging2021 to 2025$8,542,236July 15, 2021June 30, 2027DE JAGER, PHILIP Lreporter.nih.gov
MUSC Specialized Center of Research Excellence on Sex Differences Renewal 2022NIHNational Institute on Drug Abuse2021 to 2025$8,499,200September 1, 2002July 31, 2028MCRAE-CLARK, AIMEE Lreporter.nih.gov
A Latin American biobank for large-scale genetics research on severe mental illnessNIHNational Institute of Mental Health2021 to 2025$8,484,875May 1, 2020February 28, 2026FREIMER, NELSON B.reporter.nih.gov
Randomized Control Trial of oxygen therapy in Children and Adolescents with Down Syndrome and Obstructive Sleep ApneaNIHNational Heart, Lung, and Blood Institute2024 to 2025$8,481,225September 1, 2022August 31, 2027AMIN, RAOUF S.reporter.nih.gov
Use of a GLP-1 Agonist to Treat Opioid Use Disorder in Rats and ManNIHNational Institute on Drug Abuse2024 to 2025$8,480,887September 30, 2019April 30, 2027GRIGSON, PATRICIA SUEreporter.nih.gov
Preserving Cognitive Resilience: A Biracial Parent-Offspring StudyNIHNational Institute on Aging2022 to 2024$8,461,054March 1, 2019May 31, 2026RAJAN, KUMAR B.reporter.nih.gov
Functional Genomic Dissection of Alzheimer's Disease in Humans and Drosophila ModelsNIHNational Institute on Aging2021 to 2025$8,376,812July 1, 2021June 30, 2026SHULMAN, JOSHUA Mreporter.nih.gov
Genetic Architecture of Alzheimer’s disease ProteinopathiesNIHNational Institute on Aging2021 to 2024$8,376,544April 15, 2021February 28, 2026KAMBOH, M. ILYASreporter.nih.gov
Genetic Studies of Alzheimer's Disease in Jewish and Arab PopulationsNIHNational Institute on Aging2023 to 2025$8,372,205September 1, 2023August 31, 2028FARRER, LINDSAY A.reporter.nih.gov
Longitudinal validation of retinal biomarkers against cerebral imaging in preclinical Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$8,348,817September 15, 2022May 31, 2027ALBER, JESSICAreporter.nih.gov
REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction-4 (REGARDS-MI-4)NIHNational Heart, Lung, and Blood Institute2022 to 2025$8,345,645September 10, 2022July 31, 2027SAFFORD, MONIKA Mreporter.nih.gov
IMPACT-MH: Clinical and behavioral fingerprints of psychopathologyNIHNational Institute of Mental Health2024 to 2025$8,309,045August 12, 2024May 31, 2026PITTENGER, CHRISTOPHER JOHNreporter.nih.gov
ASYMMETRIC NEURODEGENERATION AND LANGUAGE IN PRIMARY PROGRESSIVE APHASIANIHNational Institute on Aging2022 to 2025$8,306,361June 15, 2022March 31, 2027MESULAM, MAREK-MARSEL Mreporter.nih.gov
Multi-omic functional assessment of novel AD variants using high-throughput and single-cell technologiesNIHNational Institute on Aging2021 to 2025$8,305,058July 1, 2021June 30, 2026MONTINE, THOMAS Jreporter.nih.gov
3/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MINNESOTANIHNational Institute on Drug Abuse2021 to 2025$8,298,588September 30, 2015March 31, 2027LUCIANA, MONICAreporter.nih.gov
Exceptional Longevity Data Management and Coordinating CenterNIHNational Institute on Aging2022 to 2025$8,296,806September 1, 2022July 31, 2027VARMA, SUSHEELreporter.nih.gov
A Humanized Monoclonal FSH Blocking Antibody for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$8,293,749September 30, 2021August 31, 2026ZAIDI, MONEreporter.nih.gov
MRI Based Presymptomatic Prediction of ASDNIHNational Institute of Mental Health2021 to 2024$8,292,562March 16, 2024January 31, 2026PRUETT, JOHN Rreporter.nih.gov
Washington University Intellectual and Developmental Disabilities Research CenterNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$8,281,463July 28, 2020May 31, 2027DOUGHERTY, JOSEPH Dreporter.nih.gov
Gulf Coast Center for Precision Environmental HealthNIHNational Institute of Environmental Health Sciences2021 to 2025$8,275,327May 15, 2019May 31, 2029WALKER, CHERYL L.reporter.nih.gov
6/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT OHSUNIHNational Institute on Drug Abuse2021 to 2025$8,270,799September 30, 2015March 31, 2027NAGEL, BONNIE J.reporter.nih.gov
Data-Driven Sleep Biomarkers of Brain Health, Heart Health, and MortalityNIHNational Heart, Lung, and Blood Institute2022 to 2025$8,267,463September 1, 2022August 31, 2026THOMAS, ROBERT JOSEPHreporter.nih.gov
Sex-based Differences in GliomaNIHNational Cancer Institute2021 to 2025$8,258,328September 14, 2020December 31, 2026LATHIA, JUSTIN D.reporter.nih.gov
Manufacturing of Drug Product, Dual Aβ/tau Vaccine for Clinical TrialsNIHNational Institute on Aging2021 to 2023$8,244,109February 1, 2019January 31, 2025AGADJANYAN, MICHAEL Greporter.nih.gov
Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey modelNIHNational Institute on Drug Abuse2021 to 2025$8,243,787August 15, 2021June 30, 2027FOX, HOWARD Sreporter.nih.gov
Development of a Long-acting Enzyme Therapy for Treatment of Cocaine AbuseNIHNational Institute on Drug Abuse2021 to 2022$8,242,506August 15, 2020April 30, 2026ZHAN, CHANG-GUOreporter.nih.gov
The Physical Biology of Neurodegeneration in Sporadic Amyotrophic Lateral Sclerosis/Frontotemporal DementiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$8,227,499September 1, 2021August 31, 2027PHATNANI, HEMALIreporter.nih.gov
COBRE in Stroke Recovery Administrative Supplement - Team ScienceNIHNational Institute of General Medical Sciences2021 to 2024$8,212,817June 2, 2014March 31, 2025KAUTZ, STEVEN A.reporter.nih.gov
GLASS-AD: Global Latinos Sequencing Study for Alzheimer's DiseaseNIHNational Institute on Aging2023 to 2025$8,212,071September 30, 2023August 31, 2028TOSTO, GIUSEPPEreporter.nih.gov
Race / Ethncicity, Hypertension and Prevention of VCID and Stroke after Intracerebral HemmorrhageNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$8,210,604February 1, 2016July 31, 2027ROSAND, JONATHANreporter.nih.gov
Tailored Non-Pharmacotherapy Services for Chronic Pain: Testing Scalable and Pragmatic Approaches - Admin SupplementNIHNational Institute on Aging2021 to 2023$8,205,902September 30, 2019August 31, 2025DEBAR, LYNN L.reporter.nih.gov
Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targetsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$8,189,971September 15, 2024August 31, 2026GITLER, AARON D.reporter.nih.gov
Combining Pregabalin with Lofexidine: Can it Increase the Success of Transition to Naltrexone?NIHNational Institute on Drug Abuse2023 to 2025$8,178,365September 30, 2019August 31, 2026KAMPMAN, KYLE MATTHEWreporter.nih.gov
Emergency General Surgery Delirium Recovery Model: A Collaborative Care InterventionNIHNational Institute on Aging2022 to 2025$8,173,947July 1, 2022June 30, 2027ZARZAUR, BEN Lreporter.nih.gov
Disordered Proteostasis as a Driver of Disease in the Aging LungNIHNational Institute on Aging2021 to 2024$8,161,610July 1, 2015March 31, 2025BUDINGER, GR SCOTTreporter.nih.gov
14/21 ABCD-USA Consortium: Research Project Site at CU BoulderNIHNational Institute on Drug Abuse2021 to 2025$8,148,103April 15, 2020March 31, 2027BANICH, MARIE Treporter.nih.gov
Alzheimer's Prevention Initiative ADAD Colombia TrialNIHNational Institute on Aging2021 to 2022$8,118,116April 1, 2017September 30, 2024REIMAN, ERIC MICHAELreporter.nih.gov
Racial/Ethnic Disparities in ADRD Risk: The Impact of Social RelationsNIHNational Institute on Aging2021 to 2024$8,105,276June 1, 2020March 31, 2026ANTONUCCI, TONI CLAUDETTEreporter.nih.gov
The Psychiatric Cell Map Initiative: Connecting Genomics, Subcellular Networks, and Higher Order PhenotypesNIHNational Institute of Mental Health2021 to 2022$8,086,271September 5, 2018June 30, 2023KROGAN, NEVAN Jreporter.nih.gov
Beyond GWAS: High Throughput Functional Genomics & Epigenome Editing to Elucidate the Effects of Genetic Associations for SchizophreniaNIHNational Institute of Mental Health2021 to 2025$8,050,699April 1, 2021January 31, 2027CRAWFORD, GREGORY Ereporter.nih.gov
Characterizing the Genetic Risk for Alzheimer Disease in African and Admixed African-American AncestriesNIHNational Institute on Aging2024 to 2025$8,032,655September 30, 2024August 31, 2029GRISWOLD, ANTHONY JOHNreporter.nih.gov
Addressing Alzheimer's Disease and Related Dementias Disparities: The American Indigenous Cognitive Assessment (AMICA) ProjectNIHNational Institute on Aging2022 to 2025$7,983,648June 1, 2022May 31, 2027JACKLIN, KRISTENreporter.nih.gov
CHARTER Plus: A resource for cutting-edge research on neurological function and mental health in people with HIV and substance use disorders across the lifespanNIHNational Institute of Mental Health2022 to 2025$7,973,681February 1, 2022November 30, 2026LETENDRE, SCOTT Lreporter.nih.gov
Sex Differences in Major Depression: Impact of Prenatal Stress-Immune and Autonomic DysregulationNIHNational Institute of Mental Health2021 to 2024$7,968,668February 1, 2020April 24, 2025GOLDSTEIN, JILL Mreporter.nih.gov
1/4 Asian Bipolar Genetics Network (A-BIG-NET)NIHNational Institute of Mental Health2022 to 2025$7,964,900September 19, 2022July 31, 2027HUANG, HAILIANGreporter.nih.gov
Indiana Diabetes Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,959,091July 6, 2015May 31, 2030EVANS-MOLINA, CARMELLAreporter.nih.gov
INCLUDE Down Syndrome Clinical Cohort Coordinating Center (DS-4C)NIHNational Heart, Lung, and Blood Institute2024 to 2025$7,956,250September 20, 2024August 31, 2029HUNTER, JESSICA EZZELLreporter.nih.gov
THE NIH PRECISION BRAIN HEALTH NETWORK: Open and Inclusive Measurement of Neuropsychological Change for AD/ADRD Primary Prevention TrialsNIHNational Institute on Aging2025$7,948,867August 1, 2025July 31, 2030SLIWINSKI, MARTIN Jreporter.nih.gov
Using Implementation Interventions and Peer Recovery Support to Improve Opioid Treatment Outcomes in Community SupervisionNIHNational Institute on Drug Abuse2021 to 2024$7,947,350August 1, 2019April 30, 2025MARTIN, ROSEMARIE Areporter.nih.gov
Development of SBS-226, a MOR agonist / DOR antagonist, for OUDNIHNational Institute on Drug Abuse2024 to 2025$7,941,988September 30, 2024August 31, 2027REICH, JEFFREYreporter.nih.gov
20/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT VCUNIHNational Institute on Drug Abuse2021 to 2025$7,897,207April 15, 2020March 31, 2027BJORK, JAMES Mreporter.nih.gov
Communication Bridge: Optimizing an evidence-based intervention for individuals with primary progressive aphasiaNIHNational Institute on Aging2023 to 2025$7,878,167September 15, 2017August 31, 2028ROGALSKI, EMILY Jreporter.nih.gov
Development of the novel mu-opioid receptor antagonist methocinnamox (MCAM) for preventing relapse and overdoseNIHNational Institute on Drug Abuse2024 to 2025$7,874,666August 15, 2024December 31, 2027FRANCE, CHARLES Preporter.nih.gov
Higher Order Chromatin and Genetic Risk for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$7,828,464September 1, 2015May 31, 2027ROUSSOS, PANAGIOTISreporter.nih.gov
Greater Southern California Node of the Clinical Trials NetworkNIHNational Institute on Drug Abuse2021 to 2025$7,788,993June 1, 2019February 29, 2032MOONEY, LARISSA JEANETTEreporter.nih.gov
Claude D. Pepper Older Americans Independence Center at YaleNIHNational Institute on Aging2021 to 2025$7,769,010September 30, 2002June 30, 2028GILL, THOMAS MICHAELreporter.nih.gov
ERICH-GENENIHNational Institute of Neurological Disorders and Stroke2021 to 2024$7,768,356August 1, 2010June 30, 2025DEMEL, STACIEreporter.nih.gov
The POINTER Neurovascular Ancillary StudyNIHNational Institute on Aging2021 to 2024$7,761,498April 15, 2020December 31, 2025BRINKLEY, TINA Ereporter.nih.gov
Interdisciplinary Research Network on Biologically Active Tau Aggregate Polymorphs from Alzheimer's Disease and Related DementiasNIHNational Institute on Aging2021 to 2025$7,757,977July 1, 2021June 30, 2027KAYED, RAKEZreporter.nih.gov
Comparing Treatment Approaches to Promote Inpatient Rehabilitation Effectiveness for Traumatic Brain Injury (CARE 4 TBI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$7,746,716September 15, 2021August 31, 2028BOGNER, JENNIFER Areporter.nih.gov
Columbia Center for Children's Environmental Health in ECHO II: Impact of environmental exposures on children's health and the co-morbidity of asthma and ADHD.NIHOffice of the Director, National Institutes of Health2023 to 2024$7,746,645September 21, 2016May 31, 2025HERBSTMAN, JULIE BETHreporter.nih.gov
Mapping the vulnerable locus coeruleus pathways in aging and ADNIHNational Institute on Aging2022 to 2025$7,731,727August 15, 2022July 31, 2027CHUNG, KWANGHUNreporter.nih.gov
Clinical development of an mGlu2 positive allosteric modulator to treat nicotine addictionNIHNational Institute on Drug Abuse2021 to 2022$7,715,052August 15, 2020July 31, 2025COSFORD, NICHOLAS DAVIDreporter.nih.gov
Behavioral Phenoscreening: Remote Assessment of Child Mental Health (REACH)NIHNational Institute of Mental Health2025$7,684,671September 1, 2025August 31, 2029THOMASON, MORIAH Ereporter.nih.gov
Long-acting naltrexone for pre-release prisoners: A randomized trial of mobile treatmentNIHNational Institute on Drug Abuse2021 to 2023$7,640,612May 1, 2023April 30, 2026GORDON, MICHAEL SCOTTreporter.nih.gov
SCAN: Standardized Centralized Alzheimer's and Related Dementias NeuroimagingNIHNational Institute on Aging2021 to 2025$7,600,838May 1, 2020April 30, 2027JAGUST, WILLIAM J.reporter.nih.gov
Vietnamese Insights into Cognitive Aging Program (VIP)NIHNational Institute on Aging2021 to 2025$7,598,841February 15, 2021May 31, 2026MEYER, OANH Lreporter.nih.gov
Reducing Opioid Mortality in Illinois (ROMI)NIHNational Institute on Drug Abuse2021 to 2023$7,594,077July 15, 2019April 30, 2025POLLACK, HAROLD ALEXANDERreporter.nih.gov
Look AHEAD Sleep: Sleep-disordered breathing, circadian rest/activity rhythms, and the risk of Alzheimer's disease and related dementias in Look AHEADNIHNational Institute on Aging2021 to 2025$7,592,411August 15, 2021May 31, 2027UDEH-MOMOH, CHINEDU THERESAreporter.nih.gov
Diabetes Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,571,345December 1, 1996December 31, 2027KAHN, STEVEN EMANUELreporter.nih.gov
Genotyping the Understanding America Study to generate novel opportunities for research on cognitive functioning and dementiaNIHNational Institute on Aging2023 to 2025$7,564,979September 15, 2023May 31, 2028GALAMA, TITUS JOHANNESreporter.nih.gov
ACE-D: Accelerating Cognition-guided signatures to Enhance translation in DepressionNIHNational Institute of Mental Health2024 to 2025$7,556,428May 3, 2024February 28, 2029WILLIAMS, LEANNEreporter.nih.gov
THE PURPOSE OF THIS CONTRACT IS TO ESTABLISH COLLECTION SITE(S) (I.E., THE NIH BRAIN AND TISSUE REPOSITORY (NBTR) TO PROVIDE SERVICES THAT WILL ACTIVELY ACQUIRE, RECEIVE, STORE, CURATE, PRESERVE, ANDNIHNational Institute on Drug Abuse2021 to 2025$7,530,975May 1, 2025October 31, 2025SCOTT, WILLIAMreporter.nih.gov
Parkinsons Disease Scalable iPSC Autologous Cell TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$7,528,144January 1, 2020December 31, 2025HALLETT, PENELOPE JANEreporter.nih.gov
A major contributor of serious multisystem disease in the elderly: varicella zoster virus-induced inflammationNIHNational Institute on Aging2021 to 2023$7,526,233March 1, 2009December 31, 2025NAGEL, MARIA ACENAreporter.nih.gov
Plasma Proteomic Signatures for Alzheimer's Disease and Related DementiasNIHNational Institute on Aging2022$7,523,227September 15, 2022August 31, 2025SHADYAB, ALADDINreporter.nih.gov
REpeated ASseSsmEnt of SurvivorS in ICH (REASSESS ICH)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$7,516,765January 1, 2022December 31, 2027ZIAI, WENDY Creporter.nih.gov
Health Systems Node of the NIDA Clinical Trials Network (CTN Project: CTN-141 Hlth Ins Instability)NIHNational Institute on Drug Abuse2021 to 2025$7,514,766March 1, 2025February 29, 2032CAMPBELL, CYNTHIA Ireporter.nih.gov
Pediatric Dose Optimization for Seizures in EMS (PediDOSE)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$7,509,102August 1, 2021November 30, 2023SHAH, MANISH ISHWARreporter.nih.gov
Institutional Career Development CoreNIHNational Center for Advancing Translational Sciences2021 to 2025$7,493,043June 1, 2017February 28, 2027MCKINNEY, CHRISTY MICHELLEreporter.nih.gov
Indigenous Cultural Understandings of Alzheimer's Disease and Related Dementias - Research and Engagement (I-CARE)NIHNational Institute on Aging2021 to 2025$7,489,463March 1, 2021February 28, 2027JACKLIN, KRISTENreporter.nih.gov
Understanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer DiseaseNIHNational Institute on Aging2021 to 2024$7,486,964February 15, 2020January 31, 2026ROUSSOS, PANAGIOTISreporter.nih.gov
Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primatesNIHNational Institute on Drug Abuse2023 to 2025$7,434,979June 1, 2023February 29, 2028RANA, TARIQ Mreporter.nih.gov
A randomized, placebo-controlled, double-blind study to evaluate safety and efficacy of NDX-1017 treatment in Alzheimer's dementia patientsNIHNational Institute on Aging2021 to 2022$7,416,643September 15, 2020May 31, 2023MOEBIUS, HANS JOERGreporter.nih.gov
Multidimensional Assessment of Brain Health as A Marker of Dementia Risk and ResilienceNIHNational Institute on Aging2021 to 2024$7,413,273September 15, 2020May 31, 2025SESHADRI, SUDHAreporter.nih.gov
Efficacy, safety, and pharmacokinetic study of BICX104 naltrexone subcutaneous implant alone and in combination with bupropion for the treatment of Methamphetamine Use Disorder (MUD).NIHNational Institute on Drug Abuse2024 to 2025$7,405,564March 1, 2024November 30, 2027DEVARNEY, KATHERINE BEEBEreporter.nih.gov
Effects of Successful OSA TreatmENT on Memory and AD BIomarkers in Older AduLts (ESSENTIAL)NIHNational Institute on Aging2023 to 2024$7,403,993September 1, 2023August 31, 2028STONE, KATIE Lreporter.nih.gov
CYCLE-AD: Randomized Controlled Trial to Assess the Efficacy of Indoor Cycling in Slowing Disease Progression in Healthy Older Persons at Genetic Risk for Alzheimer’s DiseaseNIHNational Institute on Aging2021 to 2025$7,389,501January 15, 2021December 31, 2026RAO, STEPHEN MARKreporter.nih.gov
Therapeutics targeting TDP-43 to treat Alzheimer's disease and related disordersNIHNational Institute on Aging2021 to 2025$7,375,647July 1, 2021December 31, 2026REITZ, ALLEN BERNARDreporter.nih.gov
Neurodevelopmental Mechanisms Underlying Stress Vulnerability during AdolescenceNIHNational Institute of Mental Health2021 to 2024$7,374,581July 1, 2020April 30, 2025MCLAUGHLIN, KATIEreporter.nih.gov
Predicting and Optimizing Language Outcomes in Minimally Verbal Children with Autism Spectrum DisorderNIHNational Institute on Deafness and Other Communication Disorders2021 to 2023$7,366,154September 1, 2019August 31, 2025TAGER-FLUSBERG, HELENreporter.nih.gov
Western States Node of the National Drug Abuse Treatment Clinical Trials Network (CTN-139)NIHNational Institute on Drug Abuse2021 to 2025$7,354,769March 1, 2025March 1, 2032KORTHUIS, PHILIP TODDreporter.nih.gov
Predictors of Altered CNS Structure, Function, and Connectomics in the Elderly using a Health Disparities FrameworkNIHNational Institute on Aging2022 to 2025$7,350,257February 15, 2022November 30, 2027COHEN, ANN D.reporter.nih.gov
ENVIRONMENTAL INFLUENCES ON NEURODEVELOPMENTAL OUTCOME IN INFANTS BORN VERY PRETERMNIHOffice of the Director, National Institutes of Health2021 to 2022$7,328,850September 21, 2016August 31, 2024LESTER, BARRY M.reporter.nih.gov
Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS II)NIHNational Institute on Aging2024 to 2025$7,286,036June 15, 2024November 30, 2029JOHNSON-AKEJU, OLUWASEUNreporter.nih.gov
Randomized Control Trial of oxygen therapy in Children and Adolescents with Down Syndrome and Obstructive Sleep ApneaNIHNational Heart, Lung, and Blood Institute2022 to 2023$7,285,275September 1, 2022August 31, 2024AMIN, RAOUF S.reporter.nih.gov
Leveraging the 24-hour movement paradigm to preserve cognitive function and prevent Alzheimer's disease: The Multi-Ethnic Study of Atherosclerosis (MESA) 24H-ACT StudyNIHNational Institute on Aging2021 to 2024$7,263,372May 1, 2021April 30, 2026DIAZ, KEITH Mreporter.nih.gov
Early Life Stress and the Environmental Origins of Disease: a Population-based Prospective Longitudinal Study of Children in Rural Poverty (ECHO)NIHOffice of the Director, National Institutes of Health2021 to 2022$7,262,121September 21, 2016August 31, 2024TRASANDE, LEONARDOreporter.nih.gov
The VETSA Longitudinal MRI Twin Study of Aging (VETSA MRI 4)NIHNational Institute on Aging2022 to 2025$7,252,240June 1, 2022March 31, 2027ELMAN, JEREMY Areporter.nih.gov
SUPPORT THE ONGOING OPERATIONS OF THE NATIONAL DATABASE FOR AUTISM RESEARCH - NDARNIHNational Institute on Drug Abuse2021$7,242,156January 1, 2021March 31, 2021GOODWIN, JOHNreporter.nih.gov
Identification and Characterization of Cell-Specific Transposable Elements Implicated on Alzheimer Disease and Healthy AgingNIHNational Institute on Aging2022 to 2025$7,239,829August 15, 2022June 30, 2027CRUCHAGA, CARLOSreporter.nih.gov
Genetic Architecture of Early-Onset Psychosis in Mexicans (EPIMex)NIHNational Institute of Mental Health2023 to 2025$7,156,776July 14, 2023May 31, 2028GLAHN, DAVID Creporter.nih.gov
Aging eyes and aging brains in studying alzheimer''s disease: Modern ophthalmic data collection in the adult changes in thought (ACT) studyNIHNational Institute on Aging2025$7,155,353September 1, 2019April 30, 2029LEE, CECILIA SUNGMINreporter.nih.gov
Genetics of deep-learning-derived neuroimaging endophenotypes for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$7,153,018July 1, 2021June 30, 2027ZHI, DEGUIreporter.nih.gov
Neuroplasticity-Based Computerized Cognitive Remediation (nCCR) for Treatment Resistant Late-Life DepressionNIHNational Institute of Mental Health2021 to 2025$7,151,191April 15, 2021February 28, 2027MORIMOTO, SARAH SHIZUKOreporter.nih.gov
Escitalopram for Agitation in Alzheimer DiseaseNIHNational Institute on Aging2021 to 2022$7,145,681September 30, 2016May 31, 2024LYKETSOS, CONSTANTINE Greporter.nih.gov
Elucidating single cell changes in neurogenic brain regions during HIV and cannabinoid exposureNIHNational Institute on Drug Abuse2023 to 2025$7,084,951May 15, 2023March 31, 2028NDHLOVU, LISHOMWA Creporter.nih.gov
Action for Health in Diabetes (Look AHEAD) Extended Follow-up (LA-E2)NIHNational Institute on Aging2021 to 2025$7,064,037August 1, 2021July 31, 2027ESPELAND, MARK ANDREWreporter.nih.gov
Developing a NAMPT activator for Alzheimer’s diseaseNIHNational Institute on Aging2023 to 2025$7,056,557September 15, 2023August 31, 2028CHEN, BEIBEIreporter.nih.gov
Pterygopalatine Fossa (PPF) Block as an Opioid Sparing Treatment for AcuteHeadache in Aneurysmal Subarachnold HemorrhageNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$7,048,922March 15, 2023February 28, 2027BUSL, KATHARINA MARIAreporter.nih.gov
PREcision Care In Cardiac ArrEst - ICECAP (PRECICECAP)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$7,046,260December 15, 2020April 30, 2026HIRSCH, KAREN Greporter.nih.gov
A comprehensive dissection of cell types, circuits and molecular adaptations during opioid useNIHNational Institute on Drug Abuse2021 to 2025$7,041,006June 1, 2021March 31, 2027SCHERRER, GREGORYreporter.nih.gov
Understanding the molecular mechanisms that contribute to neuropsychiatric symptoms in Alzheimer DiseaseNIHNational Institute on Aging2021 to 2023$7,036,460September 15, 2019May 31, 2025ROUSSOS, PANAGIOTISreporter.nih.gov
Autism Genetics Phase II: Increasing Representation of Human DiversityNIHNational Institute of Mental Health2025$7,009,385March 25, 2013May 31, 2028GESCHWIND, DANIEL Hreporter.nih.gov
Multi-arm Optimization of Stroke Thrombolysis (MOST) Stroke TrialNIHNational Institute of Neurological Disorders and Stroke2021$6,997,609May 1, 2021October 31, 2024ADEOYE, OPEOLU Mreporter.nih.gov
COBRE in Neurodevelopment and Its DisordersNIHNational Institute of General Medical Sciences2023 to 2025$6,991,499April 1, 2023February 29, 2028COWAN, CHRISTOPHER Wreporter.nih.gov
Integrating the exposome and methylome to inform brain molecular changes in ADRD across established diverse cohorts.NIHNational Institute on Aging2021 to 2022$6,989,910September 1, 2020August 31, 2025ERTEKIN-TANER, NILUFERreporter.nih.gov
University of Maryland Claude D. Pepper Older Americans Independence Center (OAIC)NIHNational Institute on Aging2021 to 2025$6,970,364September 15, 2006June 30, 2027RYAN, ALICE S.reporter.nih.gov
UCSF Older Americans Independence CenterNIHNational Institute on Aging2021 to 2025$6,946,581July 15, 2013June 30, 2028COVINSKY, KENNETH E.reporter.nih.gov
Multidimensional mapping of vulnerable cell types in humanized Alzheimer's disease mouse modelsNIHNational Institute on Aging2023 to 2025$6,945,316July 1, 2023March 31, 2028COBOS, INMAreporter.nih.gov
Differential Effects of Exercise Modality on Cognition and Brain in Older AdultsNIHNational Institute on Aging2021 to 2025$6,923,080April 1, 2021March 31, 2027VIDONI, ERIC DENNISreporter.nih.gov
Risk Factors for Future Cognitive Decline and Alzheimers Disease in Older African AmericansNIHNational Institute on Aging2021 to 2025$6,919,789May 15, 2018May 31, 2028GLUCK, MARK Areporter.nih.gov
Functional genomic studies in diverse populations to characterize risk loci for Alzheimer DiseaseNIHNational Institute on Aging2021 to 2025$6,908,458July 15, 2021June 30, 2027VANCE, JEFFERY MARVINreporter.nih.gov
Lifetime stressors and Alzheimer's Disease genetic variants and biomarkers in relation to cognitive decline among Black Women'sHealth Study participants.NIHNational Institute on Aging2024 to 2025$6,906,113February 15, 2024January 31, 2029ROSENBERG, LYNNreporter.nih.gov
Development of sigma receptor/DAT dual-targeting compounds to treat stimulant use disorderNIHNational Institute on Drug Abuse2023 to 2024$6,903,733August 15, 2023July 31, 2026REICH, JEFFREYreporter.nih.gov
Toward Healthy Aging in Adults with Autism: A Longitudinal Clinical and Multimodal Brain Imaging StudyNIHNational Institute of Mental Health2022 to 2024$6,900,037September 6, 2022June 30, 2027LAINHART, JANET ELIZABETHreporter.nih.gov
Person-centered quality measurement and management in a system for addictions treatment in New York StateNIHNational Institute on Drug Abuse2023 to 2025$6,873,344September 30, 2023August 31, 2028NEIGHBORS, CHARLES Jreporter.nih.gov
A Longitudinal MRI Study Characterizing Very Early Brain Development in Infants with Down SyndromeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$6,871,845September 20, 2018August 31, 2025MARRUS, NATASHAreporter.nih.gov
Clinical trials to prevent Alzheimer's Disease in Down SyndromeNIHNational Institute on Aging2022 to 2024$6,863,895September 15, 2019August 31, 2025RAFII, MICHAEL Sreporter.nih.gov
GMP Production and Extended Toxicology of an Oral Formulation Drug for Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$6,827,181June 1, 2022May 31, 2027WATTERSON, DANIEL MARTINreporter.nih.gov
Duke HEAL R-DECNIHOffice of the Director, National Institutes of Health2022 to 2023$6,823,028September 23, 2022June 30, 2025HORNIK, CHRISTOPHreporter.nih.gov
Increasing financial and health equity among low income black youth and young adultsNIHNational Institute on Minority Health and Health Disparities2023 to 2025$6,783,115September 23, 2021April 30, 2027LIPPMAN, SHERI ANNreporter.nih.gov
The adaptive-innate immune interactome across multiple tissues in Alzheimer's diseaseNIHNational Institute on Aging2023 to 2025$6,770,771May 15, 2023January 31, 2028ROUSSOS, PANAGIOTISreporter.nih.gov
Comparison of Symptom Burden/Toxicity, Neurocognitive Change, and Functional Outcomes in Pediatric Brain Tumor Patients Treated with Proton vs. Photon Radiotherapy.NIHNational Cancer Institute2021 to 2025$6,769,276March 1, 2021August 31, 2027KAHALLEY, LISA SCHUMreporter.nih.gov
Examining the Persistence of Neurocognitive Benefits of ExerciseNIHNational Institute on Aging2023 to 2025$6,759,799September 1, 2023May 31, 2028ERICKSON, KIRK Ireporter.nih.gov
Artificial Intelligence Strategies for Alzheimer's Disease ResearchNIHNational Institute on Aging2022 to 2025$6,749,268September 30, 2021August 31, 2026MOORE, JASON H.reporter.nih.gov
North Carolina Diabetes Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,742,732April 7, 2020May 31, 2028NEUFER, P DARRELLreporter.nih.gov
18/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT THE UNIVERSITY OF FLORIDANIHNational Institute on Drug Abuse2021 to 2025$6,741,640April 15, 2020March 31, 2027NIXON, SARA JOreporter.nih.gov
Center for Mesoscale MappingNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$6,740,828August 1, 2020May 31, 2030ROSEN, BRUCE Rreporter.nih.gov
12/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U PITTSBURGHNIHNational Institute on Drug Abuse2021 to 2025$6,727,386September 30, 2015March 31, 2027CLARK, DUNCAN B.reporter.nih.gov
Implementing and Personalizing Best-In-Class Opioid-sparing Pain Management for Major Inpatient Surgeries in ChildrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$6,720,269September 5, 2024August 31, 2029SADHASIVAM, SENTHILKUMARreporter.nih.gov
An Intranasal GDNF Gene Therapy for Opioid Relapse ReductionNIHNational Institute on Drug Abuse2021$6,693,512September 15, 2021August 31, 2025WASZCZAK, BARBARA LEEreporter.nih.gov
Early Life Air Pollution Exposures as a Risk Factor for Neurodevelopmental DisordersNIHNational Institute of Environmental Health Sciences2021 to 2025$6,692,816August 1, 2021July 31, 2029CORY-SLECHTA, DEBORAH Areporter.nih.gov
PDE7 Inhibitor for the Treatment of Cocaine Use DisorderNIHNational Institute on Drug Abuse2023 to 2025$6,689,019April 15, 2023March 31, 2027GAITANARIS, GEORGEreporter.nih.gov
Development of cebranopadol, a potent dual MOP/NOP agonist, for the treatment of Opioid Use Disorder (OUD)NIHNational Institute on Drug Abuse2023 to 2024$6,654,182August 15, 2023July 31, 2025GRIECO, JOSEPHreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Massachusetts General HospitalBoston, MA681$1.04 billion0$0
Yale UniversityNew Haven, CT561$951.4 million0$0
University of California, San FranciscoSan Francisco, CA640$939.1 million0$0
Washington UniversitySaint Louis, MO550$932 million0$0
Columbia University Health SciencesNew York, NY513$904.4 million0$0
Johns Hopkins UniversityBaltimore, MD631$904.2 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA549$894.4 million0$0
University of Michigan at Ann ArborAnn Arbor, MI468$754.1 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY460$733.6 million0$0
University of California, San DiegoLa Jolla, CA472$717.3 million0$0
University of PennsylvaniaPhiladelphia, PA495$685 million0$0
University of Southern CaliforniaLos Angeles, CA284$672.5 million0$0
Stanford UniversityStanford, CA436$564.1 million0$0
University of California Los AngelesLos Angeles, CA447$557.5 million0$0
University of Wisconsin-MadisonMadison, WI287$545.7 million0$0
Northwestern University at ChicagoChicago, IL347$506.1 million0$0
Emory UniversityAtlanta, GA384$490.6 million0$0
New York University School of MedicineNew York, NY248$476.9 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC403$449.5 million0$0
University of WashingtonSeattle, WA334$446.9 million0$0
University of MinnesotaMinneapolis, MN329$436.7 million0$0
Brigham and Women's HospitalBoston, MA247$430.9 million0$0
Duke UniversityDurham, NC315$419.1 million0$0
Indiana University IndianapolisIndianapolis, IN197$417.4 million0$0
University of Miami School of MedicineCoral Gables, FL142$374.5 million0$0
University of California at DavisDavis, CA242$359.2 million0$0
Weill Medical Coll of Cornell UnivNew York, NY260$350.5 million0$0
University of California-IrvineIrvine, CA220$336.5 million0$0
University of FloridaGainesville, FL282$333.9 million0$0
Vanderbilt University Medical CenterNashville, TN183$310.2 million0$0
Boston University Medical CampusBoston, MA177$297.7 million0$0
Mayo Clinic RochesterRochester, MN161$296.9 million0$0
Baylor College of MedicineHouston, TX217$285 million0$0
University of Colorado DenverAurora, CO242$276.6 million0$0
Brown UniversityProvidence, RI158$265.5 million0$0
University of Alabama at BirminghamBirmingham, AL245$259.3 million0$0
Ut Southwestern Medical CenterDallas, TX166$253.3 million0$0
University of Maryland BaltimoreBaltimore, MD200$251.2 million0$0
University of UtahSalt Lake City, UT180$250.9 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX206$242.3 million0$0
University of KentuckyLexington, KY168$241.8 million0$0
Oregon Health & Science UniversityPortland, OR217$240.9 million0$0
Medical University of South CarolinaCharleston, SC194$227.8 million0$0
Ohio State UniversityColumbus, OH181$213.9 million0$0
Wake Forest University Health SciencesWinston-Salem, NC158$208 million0$0
Albert Einstein College of MedicineBronx, NY114$195.5 million0$0
Rush University Medical CenterChicago, IL79$190.5 million0$0
University of ArizonaTucson, AZ111$186.5 million0$0
University of Texas at AustinAustin, TX145$182 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA122$181.5 million0$0
New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INCNew York, NY146$174.6 million0$0
University of CincinnatiCincinnati, OH97$173.7 million0$0
Case Western Reserve UniversityCleveland, OH145$172.4 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA143$171.5 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH122$168.6 million0$0
University of Texas HLTH Science CenterSan Antonio, TX106$166.3 million0$0
University of IowaIowa City, IA151$166 million0$0
University of VirginiaCharlottesville, VA147$163.2 million0$0
University of RochesterRochester, NY144$155.9 million0$0
University of ChicagoChicago, IL91$155.5 million0$0
Virginia Commonwealth UniversityRichmond, VA163$154.4 million0$0
Boston Children's HospitalBoston, MA129$154.2 million0$0
University of California-BerkeleyBerkeley, CA104$149.6 million0$0
Mclean HospitalBelmont, MA103$143.7 million0$0
Scripps Research Institute, theLa Jolla, CA89$143.3 million0$0
Broad Institute, Inc.Cambridge, MA53$142.2 million0$0
University of South FloridaTampa, FL87$141.1 million0$0
Vanderbilt UniversityNashville, TN197$138.9 million0$0
Northern California Institute/res/eduSan Francisco, CA31$135.1 million0$0
Beth Israel Deaconess Medical CenterBoston, MA89$130.8 million0$0
University of Illinois at ChicagoChicago, IL144$130.1 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH85$127.6 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ123$126.6 million0$0
Mayo Clinic JacksonvilleJacksonville, FL63$124.9 million0$0
Harvard Medical SchoolBoston, MA103$119.9 million0$0
Michigan State UniversityEast Lansing, MI93$119.4 million0$0
University of Kansas Medical CenterKansas City, KS61$104.1 million0$0
Massachusetts Institute of TechnologyCambridge, MA78$103.8 million0$0
Rutgers University New BrunswickNew Brunswick, NJ62$100.5 million0$0
SUNY at Stony BrookStony Brook, NY97$99.7 million0$0
Dartmouth CollegeHanover, NH48$97.7 million0$0
University of TX MD Anderson Can CTRHouston, TX81$96.3 million0$0
J. David Gladstone InstitutesSan Francisco, CA52$96 million0$0
Banner HealthPhoenix, AZ10$91.7 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA38$91.6 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA110$91.2 million0$0
University of South Carolina at ColumbiaColumbia, SC70$90.7 million0$0
University of Nebraska Medical CenterOmaha, NE73$90 million0$0
Seattle Children's HospitalSeattle, WA73$89.3 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA72$89.3 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA82$88.5 million0$0
Cognition Therapeutics, Inc.Pittsburgh, PA5$86.6 million0$0
New York UniversityNew York, NY76$86 million0$0
Drexel UniversityPhiladelphia, PA83$85.6 million0$0
Trustees of Boston UniversityBoston, MA88$85.3 million0$0
Kaiser Foundation Research InstituteOakland, CA51$84.8 million0$0
ST. Joseph's Hospital and Medical CenterPhoenix, AZ33$82.6 million0$0
University of Texas Med BR GalvestonGalveston, TX62$81.4 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY49$81.2 million0$0
ST. Jude Children's Research HospitalMemphis, TN51$81 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
202511,701$7,890,007,3550$0
202412,759$7,753,032,6490$0
202312,627$7,693,723,7410$0
202212,537$7,370,584,1060$0
202111,867$6,875,329,3640$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 145 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 32 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 31 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 25 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 23 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 21 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 12 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 10 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)PA-24-193NIHMay 7, 2027Not listedNotice number printed on 5 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)PA-24-188NIHMay 7, 2027Not listedNotice number printed on 5 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)PA-24-187NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317NIHNovember 24, 2026Not listedNotice number printed on 3 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIHJuly 17, 2027Not listedNotice number printed on 2 awards here
Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)PA-24-179NIHMay 7, 2027Not listedNotice number printed on 2 awards here
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)PAR-25-120NIHOctober 15, 2027Not listedNotice number printed on 2 awards here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)PA-25-304NIHJanuary 7, 2028Not listedNotice number printed on 2 awards here
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)PA-25-301NIHJanuary 7, 2028Not listedNotice number printed on 2 awards here
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)RFA-NS-24-031NIHJanuary 28, 2027$750,000Notice number printed on 1 award here
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)PAR-24-089NIHNovember 13, 2026$750,000Notice number printed on 1 award here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIHDecember 3, 2026Not listedNotice number printed on 1 award here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.