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Data / Research funding / Ohio / Cleveland Clinic Lerner Com-Cwru

Cleveland Clinic Lerner Com-Cwru: 448 NIH awards ($615.7M), fiscal years 2021 to 2026

Cleveland Clinic Lerner Com-Cwru in Cleveland, OH is funded under 448 NIH awards ($615.7M) in the NIH and NSF award files, read 2026-11-03. NIH fiscal years 2021 to 2025; NSF fiscal years 2022 to 2026.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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M5QFLTCTSQN6
State
Ohio

Awards

448 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Cleveland Alzheimers Disease Research CenterNIHNational Institute on Aging2021 to 2025$15,367,621September 1, 2021June 30, 2027PILLAI, JAGAN AYYAPPANreporter.nih.gov
Cell Adhesion and Signaling in Blood and Vascular CellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$12,074,218September 1, 2021November 30, 2026QIN, JUNreporter.nih.gov
Atrial Fibrillation Post-GWAS: Mechanisms to TreatmentNIHNational Heart, Lung, and Blood Institute2022 to 2025$11,309,762July 1, 2022June 30, 2027CHUNG, MINA KAYreporter.nih.gov
Alcohol and tissue injury, from mechanisms to treatmentsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$8,342,740May 1, 2016March 31, 2026NAGY, LAURA E.reporter.nih.gov
Sex-based Differences in GliomaNIHNational Cancer Institute2021 to 2025$8,258,328September 14, 2020December 31, 2026LATHIA, JUSTIN D.reporter.nih.gov
Molecular Dissection of Cytokine Crosstalk in the Tumor MicroenvironmentNIHNational Cancer Institute2022 to 2025$7,530,252September 13, 2022August 31, 2027STARK, GEORGE ROBERTreporter.nih.gov
CYCLE-AD: Randomized Controlled Trial to Assess the Efficacy of Indoor Cycling in Slowing Disease Progression in Healthy Older Persons at Genetic Risk for Alzheimer’s DiseaseNIHNational Institute on Aging2021 to 2025$7,389,501January 15, 2021December 31, 2026RAO, STEPHEN MARKreporter.nih.gov
Gut Microbiota and Cardiometabolic DiseasesNIHNational Heart, Lung, and Blood Institute2021 to 2023$7,273,070September 1, 2019July 31, 2025HAZEN, STANLEY Lreporter.nih.gov
Dementia with Lewy Bodies ConsortiumNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$6,563,373September 30, 2016August 31, 2027LEVERENZ, JAMES BRUCEreporter.nih.gov
Genomic and Microenvironmental Determinants, Temporal Dynamics, and Treatment Efficacy of Radiation-Based Combination TherapiesNIHNational Cancer Institute2022 to 2025$6,280,793September 14, 2022July 31, 2027CHAN, TIMOTHY AN-THYreporter.nih.gov
Randomized Trial of Assisted Ambulation to Improve Health Outcomes for Older Medical InpatientsNIHNational Institute on Aging2022 to 2025$5,979,214August 1, 2022June 30, 2027ROTHBERG, MICHAEL Breporter.nih.gov
Defining the viral PTMome: Towards the development of novel antiviral approachesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,635,000September 30, 2021July 31, 2026GACK, MICHAELA ULRIKEreporter.nih.gov
Central Vein Sign: A Diagnostic Biomarker in Multiple SclerosisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$5,233,917July 1, 2020June 30, 2026ONTANEDA, DANIELreporter.nih.gov
Assessing Novel Biomarkers for Cognitive Fluctuations in DLBNIHNational Institute of Neurological Disorders and Stroke2025$4,924,374September 1, 2025July 31, 2029PILLAI, JAGAN AYYAPPANreporter.nih.gov
Alzheimer's MultiOme Data Repurposing: Artificial Intelligence, Network Medicine, and Therapeutics DiscoveryNIHNational Institute on Aging2021 to 2025$3,966,759September 1, 2021August 31, 2026CHENG, FEIXIONGreporter.nih.gov
Towards Precision Immuno-Oncology: Unraveling the Genomic Determinants and Mechanisms Underlying Immunotherapy Efficacy and ResistanceNIHNational Cancer Institute2021 to 2024$3,811,506May 1, 2020August 31, 2025CHAN, TIMOTHY AN-THYreporter.nih.gov
Variation in tumor-associated immune profiles and colorectal cancer outcomesNIHNational Cancer Institute2021 to 2025$3,497,316September 15, 2021August 31, 2027SCHMIT, STEPHANIE L.reporter.nih.gov
Pathogenesis of Neurological Disability in Primary Diseases of MyelinNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,460,848December 1, 2016November 30, 2025TRAPP, BRUCE Dreporter.nih.gov
BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL ReconstructionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$3,403,884August 1, 2018July 31, 2025SPINDLER, KURT PAULreporter.nih.gov
Cleveland COPE-AKI Clinical CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,307,197July 19, 2021June 30, 2028POGGIO, EMILIO DANIELreporter.nih.gov
Prospective evaluation of outcomes in cirrhosis of different etiologies: impact of HIV infection and simvastatin therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,276,651September 23, 2021July 31, 2027DASARATHY, SRINIVASANreporter.nih.gov
TREM2 Genotype-Informed Drug Repurposing and Combination Therapy Design for Alzheimer’s DiseaseNIHNational Institute on Aging2022 to 2025$3,240,062July 15, 2022March 31, 2027CHENG, FEIXIONGreporter.nih.gov
A Cognitive Risk Calculator and Screening tool for Primary Care SettingsNIHNational Institute on Aging2022 to 2024$3,228,752September 30, 2020August 31, 2025FLODEN, DARLENEreporter.nih.gov
NEI Center Core Grant for Vision ResearchNIHNational Eye Institute2021 to 2025$3,220,006September 1, 2016June 30, 2026ANAND-APTE, BELAreporter.nih.gov
Imaging post-traumatic osteoarthritis 10-years after ACL reconstruction: a multicenter cohort study with quantitative MRINIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$3,194,922July 16, 2019June 30, 2025LI, XIAOJUANreporter.nih.gov
Complement regulates macrophage and platelet function in kidney transplantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,127,980September 17, 2021August 31, 2026BALDWIN, WILLIAM Mreporter.nih.gov
Endophenotype Network-based Approaches to Prediction and Population-based Validation of in Silico Drug Repurposing for Alzheimer’s DiseaseNIHNational Institute on Aging2021 to 2024$3,070,887April 15, 2020December 31, 2025CHENG, FEIXIONGreporter.nih.gov
Acute Antibody Mediated Kidney Allograft RejectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,037,635September 17, 2021August 31, 2026FAIRCHILD, ROBERT Lreporter.nih.gov
Therapeutic Implications of Molecular Defects in Bone Marrow FailureNIHNational Heart, Lung, and Blood Institute2021 to 2023$3,016,565January 12, 2017December 31, 2023MACIEJEWSKI, JAROSLAW P.reporter.nih.gov
Mechanisms of alloantibody production following renal transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,014,441February 22, 2021January 31, 2027VALUJSKIKH, ANNAreporter.nih.gov
Targeting TET DNA Dioxygenases as Therapeutic Principle in Myeloid NeoplasmsNIHNational Cancer Institute2021 to 2025$2,986,870July 1, 2021June 30, 2026MACIEJEWSKI, JAROSLAW P.reporter.nih.gov
Optimizing Lung Transplant Benefit Using Agent-Based Simulation Modeling ApproachesNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,960,354June 1, 2020April 30, 2029VALAPOUR, MARYAMreporter.nih.gov
RADIOMIC APPROACHES TO IMPROVE TARGETING FOR ATRIAL FIBRILLATION CATHETER ABLATIONNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,935,937July 15, 2021June 30, 2025CHUNG, MINA KAYreporter.nih.gov
Multi-Vendor Multi-Site Novel Accelerated MRI RelaxometryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,931,322May 1, 2020April 30, 2027LI, XIAOJUANreporter.nih.gov
Cardiothoracic Surgical Trials NetworkNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,925,675July 1, 2007February 28, 2027GILLINOV, ALAN MARCreporter.nih.gov
Exploiting Ecology and Evolution to Prevent Therapy Resistance in EGFR-Driven Lung CancerNIHNational Cancer Institute2021 to 2025$2,890,525December 1, 2024November 30, 2026SCOTT, JACOB GARDINIERreporter.nih.gov
Discovering the role of YES1 in triple negative breast cancerNIHNational Cancer Institute2021 to 2025$2,805,224February 1, 2021January 31, 2027KERI, RUTH A.reporter.nih.gov
Intracellular functions of APOL1 in the kidneyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,802,067September 23, 2021May 31, 2026BRUGGEMAN, LESLIE Areporter.nih.gov
Gut Flora metabolism of dietary carnitine and cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,763,113August 1, 2010April 30, 2026HAZEN, STANLEY Lreporter.nih.gov
New mouse model of cisplatin-induced AKI and development of prevention therapyNIHNational Cancer Institute2021 to 2025$2,680,156August 1, 2021July 31, 2026ZHAO, JIANJUNreporter.nih.gov
1/2 Pomalidomide for Bleeding in Patients with Hereditary Hemorrhagic Telangiectasia (HHT)NIHNational Heart, Lung, and Blood Institute2021 to 2023$2,676,312March 15, 2020February 28, 2026MCCRAE, KEITH R.reporter.nih.gov
Identifying novel Parkinson'’s disease genes exploring understudied Latino populationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,667,664August 1, 2020July 31, 2025FERNANDEZ MATA, IGNACIOreporter.nih.gov
Optimization of CaMPARI for large-scale, cellular-resolution activity recording in freely-moving miceNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,646,453September 1, 2021December 31, 2026DANA, HOD MICHAELreporter.nih.gov
Eltombopag: Novel Mode of Action on Normal and Aplastic Anemia Hematopoietic Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,608,897August 15, 2022May 31, 2027MACIEJEWSKI, JAROSLAW P.reporter.nih.gov
Multi-Omic Biomarkers for Neuropathic Pain Secondary to ChemotherapyNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,568,308September 30, 2020August 31, 2025ROTROFF, DANIELreporter.nih.gov
Chronic Antibody-Mediated Rejection of Kidney AllograftsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,566,057February 1, 2022January 31, 2027FAIRCHILD, ROBERT Lreporter.nih.gov
Platelets as Biosensors and Mediators of Aortic Aneurysm GrowthNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,499,163July 1, 2021June 30, 2027CAMERON, SCOTT JAMESreporter.nih.gov
FGF and hyaluronan-mediated alterations in epithelial-mesenchymal transition and metabolism of RPE cells in Sorsby Fundus Dystrophy.NIHNational Eye Institute2021 to 2024$2,497,198April 1, 2017March 31, 2026ANAND-APTE, BELAreporter.nih.gov
Genetic modifiers of atherosclerosis and macrophage phenotypesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,457,383July 1, 2021June 30, 2026SMITH, JONATHAN Dreporter.nih.gov
Advanced Imaging and Simulation Tools for Personalized Corneal Disease Assessment and SurgeryNIHNational Eye Institute2022 to 2025$2,454,968July 1, 2022June 30, 2027DUPPS, WILLIAM JOSEPHreporter.nih.gov
Post-Transplant Inflammatory ResponseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,437,884April 1, 1997November 30, 2029FAIRCHILD, ROBERT Lreporter.nih.gov
Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Center-Cleveland siteNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,432,868June 15, 2002June 30, 2027DASARATHY, SRINIVASANreporter.nih.gov
Comprehensive Augmented Reality Testing (CART) Platform for Parkinson’s diseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,416,358September 1, 2022July 31, 2027ALBERTS, JAY L.reporter.nih.gov
High resolution transcriptome and gene regulatory mapping of human ureter and bladder across the lifespanNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,415,000September 30, 2021July 31, 2027WESSELY, OLIVERreporter.nih.gov
Designing induction therapies to target memory T cells in high risk recipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,405,990July 15, 2014August 31, 2027VALUJSKIKH, ANNAreporter.nih.gov
Model-based methods for single cell chromatin interactomic dataNIHNational Human Genome Research Institute2021 to 2025$2,402,915September 22, 2021June 30, 2027HU, MINGreporter.nih.gov
Iron Dysregulation and Neuropsychiatric Complications of HIV Across the Lifespan: Impact of Biologic Factors, Antiretroviral Therapy and GeneticsNIHNational Institute of Mental Health2021 to 2025$2,401,925March 1, 2021December 31, 2025KALLIANPUR, ASHA Rreporter.nih.gov
Contribution of Myeloid-Derived Suppressor Cells to Neuro-Inflammatory Alterations and Disease Progression in GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,398,824May 1, 2022April 30, 2030LATHIA, JUSTIN D.reporter.nih.gov
Alzheimer's Disease and Related Dementia-like Sequelae of SARS-CoV-2 Infection: Virus-Host Interactome, Neuropathobiology, and Drug RepurposingNIHNational Institute on Aging2023$2,394,473May 15, 2023April 30, 2026CHENG, FEIXIONGreporter.nih.gov
Characterize neuronal and glial cell-specific vulnerability to proteinopathies in Alzheimer's disease using multimodal single-nuclei genomic and epigenomic approachesNIHNational Institute on Aging2023 to 2025$2,391,375September 1, 2023May 31, 2028CHENG, FEIXIONGreporter.nih.gov
The role of hippocampal neurogenesis in alcohol withdrawal seizure and cognitionNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,379,308April 10, 2020March 31, 2026SUH, HOONKYOreporter.nih.gov
Unraveling strain-level variation in the induction of anti-inflammatory responses in the intestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,378,553January 1, 2021December 31, 2026AHERN, PHILIP PATRICKreporter.nih.gov
Manipulation of host factors that promote HCMV latencyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,372,365March 15, 2021February 28, 2027O'CONNOR, CHRISTINE Mreporter.nih.gov
Sensing active movement of the self: reconsidering the cellular basis kinesthesiaNIHNational Center for Complementary & Integrative Health2022 to 2025$2,365,503May 6, 2022January 31, 2027MARASCO, PAUL D.reporter.nih.gov
Improving Phenotypic Classification and Prediction of Treatment Outcomes in Patients with Non-ischemic Cardiomyopathy and Functional Mitral RegurgitationNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,357,020July 10, 2023April 30, 2028KWON, DEBORAHreporter.nih.gov
Dark GPCR signaling underlying the Microbiome-Gut-Brain Axis for Alzheimer's Disease and Related DementiaNIHNational Institute of Neurological Disorders and Stroke2023$2,344,291August 18, 2023July 31, 2026CHENG, FEIXIONGreporter.nih.gov
Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric OutcomesNIHNational Human Genome Research Institute2023 to 2025$2,343,205September 14, 2017February 28, 2027FARRELL, RUTHreporter.nih.gov
Machine and deep learning for finding multimodal imaging biomarkers in prodromal ADNIHNational Institute on Aging2021$2,331,558April 1, 2021March 31, 2024CORDES, DIETMARreporter.nih.gov
Reassortment of Bunyavirus in ticks and animal modelsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,326,633August 19, 2022July 31, 2027JUNG, JAE Ureporter.nih.gov
Single Visit Clinical Validation of ScreenFire, a Low-Cost HPV Test: Efficacy and Cost Effectiveness (SCALE)NIHNational Cancer Institute2022 to 2025$2,315,714April 1, 2022March 31, 2027CREMER, MIRIAMreporter.nih.gov
Nitric Oxide in Pulmonary HypertensionNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,291,952April 1, 1999December 31, 2025ERZURUM, SERPIL C.reporter.nih.gov
Novel Role for Host Immunostimulatory RNA in Antiviral Immune DefenseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,281,556September 22, 2021August 31, 2026GACK, MICHAELA ULRIKEreporter.nih.gov
Hypertension augmented COVID-19 through renin-induced internalization of platelet-ACE2 / SARS-Cov-2 complexesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,277,916September 20, 2021August 31, 2025MCINTYRE, THOMAS Mreporter.nih.gov
Immune cell activation and associated blood brain barrier changes across different stages of Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$2,270,781September 1, 2022May 31, 2028PILLAI, JAGAN AYYAPPANreporter.nih.gov
SFTSV nonstructural protein NSs-mediated immunopathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,260,994July 1, 2018June 30, 2024JUNG, JAE Ureporter.nih.gov
Tickborne SFTS Virus Vaccine DevelopmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,258,000August 3, 2020July 31, 2026JUNG, JAE Ureporter.nih.gov
AS160 as a nodal regulator of the cardiac response to metabolic stressNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,241,409August 1, 2022July 31, 2027SCHUMACHER, SARAH MARIEreporter.nih.gov
Regulation of Host Innate Immunity Against Viral InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,230,417April 1, 2010May 31, 2026GACK, MICHAELA ULRIKEreporter.nih.gov
Extending experimental evolutionary game theory in cancer in vivo to enable clinical translation: integrating spatio-temporal dynamics using mathematical modelingNIHNational Cancer Institute2023 to 2025$2,229,645August 1, 2023July 31, 2028SCOTT, JACOB GARDINIERreporter.nih.gov
Novel mechanism based treatment to improve tissue injury in alcoholic hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,223,387September 25, 2020July 31, 2025DASARATHY, SRINIVASANreporter.nih.gov
Gut-microbial metabolism of aromatic amino acids and cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,221,265December 15, 2021November 30, 2026NEMET, INAreporter.nih.gov
Clinical and Economic Impact of Teleneurology vs Standard in Clinic Care for Multiple Sclerosis: A Randomized TrialNIHNational Institute of Nursing Research2022 to 2025$2,209,310September 26, 2022June 30, 2027MCGINLEY, MARISAreporter.nih.gov
Mechanisms controlling the efficiency of hemostatic vitamin K-dependent protein activationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,201,245April 1, 2021March 31, 2026BERKNER, KATHLEEN LUCILEreporter.nih.gov
Improving intracortical control of reaching after paralysisNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,197,457July 1, 2020June 30, 2026TAYLOR, DAWN MARIEreporter.nih.gov
lncRNA regulation of glioblastoma progression and therapeutic resistanceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,168,484December 1, 2021November 30, 2026YU, JENNIFER Sreporter.nih.gov
HCMV GPCR functions during latency and reactivationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,168,053March 18, 2021February 28, 2027O'CONNOR, CHRISTINE Mreporter.nih.gov
Mechanisms of cancer immunotherapy-associated thrombosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,146,502April 15, 2023March 31, 2027MCCRAE, KEITH R.reporter.nih.gov
Testing the Effectiveness of Individualized Disease Prevention for Middle-Aged AdultsNIHNational Institute on Aging2021 to 2023$2,132,124July 1, 2019April 30, 2025TAKSLER, GLENreporter.nih.gov
Metaorganismal Endocrinology in Cardiometabolic DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,105,517August 13, 2021May 31, 2026BROWN, JONATHAN MARKreporter.nih.gov
TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,097,481February 1, 2021January 31, 2027SCHERAGA, RACHEL GREENBERGreporter.nih.gov
Impact of gamma-glutamyl carboxylase processivity on vitamin K-dependent protein modification and function in human health and diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,096,222August 1, 2021May 31, 2025BERKNER, KATHLEEN LUCILEreporter.nih.gov
A place-based approach to geographic disparities in lung transplantNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,075,369August 1, 2023May 31, 2028TSUANG, WAYNE Mreporter.nih.gov
Alcohol and intestinal microvascular endothelium-immune axis and the role of gut derived immune nutrientsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$2,049,465September 1, 2020July 31, 2026CRESCI, GAIL ANNreporter.nih.gov
Systemic Neurotropic virus infection effects on GI DysmotilityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,043,482July 1, 2020April 30, 2025STAPPENBECK, THADDEUS Sreporter.nih.gov
A first in class, mechanism-guided, cell-based therapy for complex regional pain syndromeNIHNational Institute of Neurological Disorders and Stroke2022$2,033,135September 24, 2022August 31, 2025CHENG, JIANGUOreporter.nih.gov
Deep Brain Stimulation of the Cerebellar Dentate Nucleus to Enhance Chronic, Post-Traumatic Brain Injury RehabilitationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,019,158July 1, 2020June 30, 2026BAKER, KENNETH Breporter.nih.gov
Intestinal T cells and microbiota as therapeutic targets in autoimmune uveitisNIHNational Eye Institute2022 to 2025$2,018,294September 1, 2021June 30, 2027LIN, PHOEBEreporter.nih.gov
Uncovering aryl polyene biology to identify new drug targets in Gram-negative bacterial pathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,012,500April 1, 2021March 31, 2027CLAESEN, JANreporter.nih.gov
Novel cytoskeletal mechanisms of pathogenic bacteria interactions with intestinal epitheliumNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,007,027July 15, 2022April 30, 2027IVANOV, ANDREI IVANOVICHreporter.nih.gov
Mechanisms of Kidney Diseases Associated With APOL1 VariationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,973,997February 2, 2023December 31, 2026SEDOR, JOHN R.reporter.nih.gov
Structural analysis and therapeutic nanobody development of KSHV G-protein coupled receptorNIHNational Cancer Institute2021 to 2024$1,963,648September 4, 2020May 31, 2026JUNG, JAE Ureporter.nih.gov
Clinical genetics of drug-resistant epilepsy with focal cortical dysplasiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,963,087April 15, 2021June 30, 2023LAL, DENNISreporter.nih.gov
Development of three KSHV vaccine platforms and chimeric MHV68-K-G for in vivo mouse infection studyNIHNational Cancer Institute2024 to 2025$1,962,036September 19, 2024August 31, 2029JUNG, JAE Ureporter.nih.gov
Immuno-metabolic dysfunction in alcohol with sepsisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,961,505September 20, 2021July 31, 2027VACHHARAJANI, VIDULAreporter.nih.gov
The role of the astrocyte immunoproteasome during chronic CNS autoimmunityNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,960,175December 1, 2020November 30, 2026WILLIAMS, JESSICA Lreporter.nih.gov
Using patient-level decision modeling to improve use of treatments for alcohol use disorderNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,949,796September 15, 2023June 30, 2028LE, PHUCreporter.nih.gov
Immune Mechanisms Underlying the Neuroprotective Effects of Physical Activity in Human and Mouse Models of Genetic Risk for Alzheimers DiseaseNIHNational Institute on Aging2021$1,943,194May 1, 2003May 31, 2023RAO, STEPHEN MARKreporter.nih.gov
Developing a renewable and dissectible human liver for the study of HBV/HCV infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,932,000August 18, 2022July 31, 2027WU, XIANFANGreporter.nih.gov
Novel approaches to improve prediction of cancer-associated thrombosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,925,190August 1, 2018July 31, 2025MCCRAE, KEITH R.reporter.nih.gov
Molecular basis of ILK-mediated cell adhesionNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,905,818January 1, 1999March 31, 2028QIN, JUNreporter.nih.gov
Novel regulation of beta-adrenergic receptor function by phosphoinositide 3-kinaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,900,437December 15, 2022November 30, 2026PRASAD, SATHYAMANGLA Vreporter.nih.gov
The role of NUDT16 in DNA damage response and tumorigenesisNIHNational Cancer Institute2021 to 2025$1,900,364December 1, 2018July 31, 2029GONG, ZIHUAreporter.nih.gov
Adipokines, Aging, and Alzheimers DiseaseNIHNational Institute on Aging2021 to 2024$1,897,892June 15, 2020March 31, 2025FOX, PAUL Lreporter.nih.gov
Activity and connectivity of hippocampal newborn neurons underlie alcohol withdrawal-associated syndromesNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,897,725August 15, 2023May 31, 2028SUH, HOONKYOreporter.nih.gov
The mammalian multi-tRNA synthetase complexNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,880,219December 1, 2021November 30, 2026FOX, PAUL Lreporter.nih.gov
Ketamine Treatment of Youth Suicide Attempters for Fast Reduction of Severe Suicide Risk and Facilitation of Long-term Collaborative Clinical Engagement: A Randomized Placebo Controlled TrialNIHNational Institute of Mental Health2021 to 2025$1,869,024September 15, 2020August 31, 2026FALCONE, TATIANAreporter.nih.gov
Septins in intestinal fibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,865,031May 1, 2023April 30, 2027RIEDER, FLORIANreporter.nih.gov
Childhood-onset hypomyelinating leukodystrophy and the multi-tRNA synthetase complexNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,861,106December 15, 2022November 30, 2027FOX, PAUL Lreporter.nih.gov
Digital Twin Neighborhoods for Research on Geographic Patterns in Mid-Life Health TrajectoriesNIHNational Institute on Aging2023 to 2025$1,854,705January 1, 2023December 31, 2027DALTON, JARRODreporter.nih.gov
Interactions of Sex and Gender Factors in Risk for Alzheimers Disease: Links Between Stress, Neural Activity, Inflammation, and MemoryNIHNational Institute on Aging2021 to 2024$1,849,427August 1, 2021April 30, 2026KIRKLAND CALDWELL, JESSICAreporter.nih.gov
Identifying Circuit Dynamics Underlying Motor Dysfunction in Parkinson’s Disease Using Real-Time Neural ControlNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,831,432July 1, 2023June 30, 2028ESCOBAR SANABRIA, DAVIDreporter.nih.gov
Serial evaluation of cardioprotective effects of exercise training in heart failure using cardiac diffusion tensor MRINIHNational Heart, Lung, and Blood Institute2022 to 2024$1,817,778November 4, 2022May 31, 2026NGUYEN, CHRISTOPHER Treporter.nih.gov
Reproducibility in simulation-based prediction of natural knee mechanicsNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,817,682September 1, 2023August 31, 2027ERDEMIR, AHMETreporter.nih.gov
Contralaterally Controlled FES Combined with Brain Stimulation for Severe Upper limb HemiplegiaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2024$1,815,195May 1, 2019April 30, 2026PLOW, ELA Breporter.nih.gov
The role of acetogenic, methanogenic, and sulfate-reducing bacteria in oxalate metabolism and hyperoxaluriaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,811,784April 17, 2020February 28, 2026MILLER, AARON Wreporter.nih.gov
Biological determinants of colorectal cancer outcomes in Latinos of diverseýancestral originsNIHNational Cancer Institute2021 to 2024$1,811,473May 1, 2021April 30, 2025SCHMIT, STEPHANIE L.reporter.nih.gov
The Role of TRIM23 in Autophagy Mediated Antiviral DefensesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,809,998June 1, 2020May 31, 2025GACK, MICHAELA ULRIKEreporter.nih.gov
Mechanisms of nuclear Mcl-1 mediated chemoresistanceNIHNational Cancer Institute2021 to 2025$1,808,294December 4, 2020November 30, 2025MELENHORST, JAN Jreporter.nih.gov
IRAKM and MINCLE in ALDNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2025$1,806,489August 17, 2023July 31, 2028NAGY, LAURA E.reporter.nih.gov
Understanding role of circadian disruption in pathogenesis of MSNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,795,603March 1, 2022February 28, 2027DUTTA, RANJANreporter.nih.gov
KUH-TN Training CoreNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,765,732September 15, 2021May 31, 2027STAVROU, EVI X.reporter.nih.gov
Transcriptional and non-transcriptional function of IRF3 in ALDNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,763,975July 5, 2019June 30, 2029NAGY, LAURA E.reporter.nih.gov
Understanding and Using Variation in Source Materials for MSC FabricationNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,762,373August 14, 2019April 30, 2025MUSCHLER, GEORGE Freporter.nih.gov
CYClical Lower Extremity exercise for Parkinsons trial (CYCLE Trial)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,752,215September 1, 2011April 30, 2026ALBERTS, JAY L.reporter.nih.gov
Molecular Basis of KSHV oncogenesisNIHNational Cancer Institute2021 to 2022$1,726,428March 1, 2016February 28, 2023JUNG, JAE Ureporter.nih.gov
Combined Training Program in Digestive Disease SciencesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,723,447July 1, 2009March 31, 2027FIOCCHI, CLAUDIOreporter.nih.gov
KSHV Epigenetic RegulationNIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,716,021September 15, 2020November 30, 2024JUNG, JAE Ureporter.nih.gov
Cleveland Precision Medicine Chronic Kidney Disease CohortNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,690,576September 15, 2017June 30, 2027O'TOOLE, JOHN F.reporter.nih.gov
Software for Practical Annotation and Exchange of Virtual AnatomyNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$1,689,780July 2, 2019March 31, 2025ERDEMIR, AHMETreporter.nih.gov
Two novel threonine phosphorylations of STAT2 impact inflammatory responses to bacterial infection.NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,687,938August 7, 2020July 31, 2024STARK, GEORGE ROBERTreporter.nih.gov
Inflammatory Signaling and Regeneration in Zebrafish models of Retinal DegenerationNIHNational Eye Institute2023 to 2025$1,676,798September 1, 2023January 31, 2027PERKINS, BRIAN Dreporter.nih.gov
A novel regulator of Pseudomonas aeruginosa keratitisNIHNational Eye Institute2021 to 2023$1,662,832May 1, 2020April 30, 2026LIN, FENG Creporter.nih.gov
Microglial Activation and Inflammatory Endophenotypes Underlying Sex Differences of Alzheimer’s DiseaseNIHNational Institute on Aging2023 to 2025$1,657,399September 22, 2023May 31, 2027CHENG, FEIXIONGreporter.nih.gov
Gut Microbiota and Cerebral Vascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,654,119August 1, 2020July 31, 2025ZHU, WEIFEIreporter.nih.gov
Modeling Autism and Comorbid Cancer Risk in Individuals with Germline PTEN MutationsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$1,616,998September 14, 2022June 30, 2027NI, YINGreporter.nih.gov
Defining a pathway for mitochondrial heme traffickingNIHNational Institute of General Medical Sciences2023 to 2025$1,610,870September 1, 2023August 31, 2027STUEHR, DENNIS Jreporter.nih.gov
Role of the TLR4 signaling in smooth muscle cell phenotypic transitionNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,610,000August 1, 2021July 31, 2026CHEREPANOVA, OLGAreporter.nih.gov
Early Stage Studies of a Novel Positive Allosteric Modulator of the Alpha1-Adrenergic Receptor to Treat Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2024$1,610,000May 15, 2020March 31, 2026PEREZ, DIANNE Mreporter.nih.gov
Profibrotic Mechanisms of the TRPV4-PI3K-gamma Protein ComplexNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,610,000August 1, 2021December 31, 2025OLMAN, MITCHELL ALANreporter.nih.gov
Molecular Mechanisms of TULP1-Mediated Photoreceptor DegenerationNIHNational Eye Institute2022 to 2025$1,610,000May 1, 2022April 30, 2027HAGSTROM, STEPHANIE Areporter.nih.gov
Mechanisms of retinal degeneration in neuroinflammatory demyelinating diseasesNIHNational Eye Institute2021 to 2024$1,597,925January 1, 2021November 30, 2025DESILVA, TARA MARIAreporter.nih.gov
New mechanisms by which complementýregulates the pathogenesis of experimental autoimmune uveitisNIHNational Eye Institute2021 to 2024$1,597,925May 1, 2021April 30, 2026LIN, FENG Creporter.nih.gov
Multi-organ protection from hyperoxia of the severely premature infantNIHNational Eye Institute2021 to 2025$1,597,925August 1, 2015May 31, 2029SEARS, JONATHAN Ereporter.nih.gov
Reprograming Macrophages and Targeting Glioma Stem Cells in GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,597,925August 1, 2022July 31, 2027BAO, SHIDENGreporter.nih.gov
A novel determinant of prostate cancer growthNIHNational Cancer Institute2021 to 2025$1,596,877April 1, 2021March 31, 2026HEEMERS, HANNELOREreporter.nih.gov
Determining the Efficacy of Corneal Cross-Linking Protocols using Brillouin MicroscopyNIHNational Eye Institute2022 to 2025$1,593,267July 1, 2022June 30, 2027RANDLEMAN, JAMES BRADLEYreporter.nih.gov
Novel unconventional myosins in B cell homeostasisNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,587,906June 1, 2023May 31, 2028GUPTA, NEETUreporter.nih.gov
Innate immune responses to tissue infection by intestinal fungi inhibit wound repairNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,580,412November 14, 2023October 31, 2028STAPPENBECK, THADDEUS Sreporter.nih.gov
Gut microbial dietary phenylalanine metabolism and heart failureNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,580,134January 5, 2024December 31, 2027HAZEN, STANLEY Lreporter.nih.gov
Molecular Medicine Training Program at Cleveland Clinic/Case Western Reserve UniversityNIHNational Institute of General Medical Sciences2021 to 2025$1,574,001July 1, 2021June 30, 2026SMITH, JONATHAN Dreporter.nih.gov
Comparison of cervical intraepithelial neoplasia 2/3 treatment outcomes with a portable LMIC-adapted thermal ablation device vs. gas-based cryotherapyNIHNational Cancer Institute2021 to 2023$1,573,574January 12, 2018June 30, 2025CREMER, MIRIAMreporter.nih.gov
Machine and deep learning for finding multimodal imaging biomarkers in prodromal ADNIHNational Institute on Aging2024 to 2025$1,573,529April 1, 2021March 31, 2027CORDES, DIETMARreporter.nih.gov
Nutrition, terminal NAD metabolites and cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,568,658June 1, 2024April 30, 2028HAZEN, STANLEY Lreporter.nih.gov
Feasibility and Acceptability of Telephone-delivered MBCT for Migraine and Depression (FATE-MD)NIHNational Center for Complementary & Integrative Health2023 to 2024$1,561,381June 1, 2021May 31, 2026SHALLCROSS, AMANDA Jreporter.nih.gov
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD)- Cleveland Clinic Clinical CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$1,561,055August 1, 2018June 30, 2029DASARATHY, SRINIVASANreporter.nih.gov
Identifying multimodal biomarkers for autologous serum tears in the treatment of chronic postoperative ocular painNIHNational Institute of Neurological Disorders and Stroke2023$1,557,093September 20, 2023September 30, 2025SAYEGH, RONY ROGERreporter.nih.gov
Creeping fat and Crohn's disease associated stricturesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,556,335July 15, 2020March 31, 2026RIEDER, FLORIANreporter.nih.gov
Novel oxidative pathway targets microglia in Alzheimer's diseaseNIHNational Institute on Aging2024 to 2025$1,550,345August 15, 2024May 31, 2029BYZOVA, TATIANA Vreporter.nih.gov
Imaging Assessments of ARPKD Kidney Disease ProgressionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,546,644August 20, 2019February 28, 2029DELL, KATHERINE MACRAEreporter.nih.gov
Hydrogen sulfide functions as a tumor suppressor in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,529,987April 1, 2023February 29, 2028HINE, CHRISTOPHER MICHAELreporter.nih.gov
Role of CDCP1 in the pathogenesis of autoimmune uveitisNIHNational Eye Institute2023 to 2025$1,512,033July 1, 2023June 30, 2028LIN, FENG Creporter.nih.gov
Regulation of B cells in the CNSNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,502,050September 15, 2013March 31, 2026BERGMANN, CORNELIAreporter.nih.gov
Molecular Genetic Dissection of Fenestrated Vascular Development in the Choroid PlexusNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,502,050September 1, 2020June 30, 2026MATSUOKA, RYOTAreporter.nih.gov
Cleveland Kidney, Urology and Hematology Training NetworkNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,480,500September 15, 2021May 31, 2027SEDOR, JOHN R.reporter.nih.gov
Supporting Multidisciplinary Achievement in Respiratory Research Training (SMARRT)NIHNational Heart, Lung, and Blood Institute2021 to 2025$1,456,129July 1, 2021June 30, 2027DWEIK, RAED A.reporter.nih.gov
Live-Cell Chromatin Imaging and Biology: Application to Extrachromosomal DNANIHNational Institute of General Medical Sciences2023$1,449,000September 1, 2023August 31, 2026XIE, LIANGQIreporter.nih.gov
ApoA1 lipidation by ABCA1 in HDL biogenesisNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,438,368April 1, 2016June 30, 2025SMITH, JONATHAN Dreporter.nih.gov
Gliovascular Mechanisms of Blood-Brain Barrier Disruption in Neuroinflammatory DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,438,273August 1, 2019April 30, 2025DAVALOS, DIMITRIOSreporter.nih.gov
Targeting oncogenic dopamine receptor signaling in glioblastomaNIHNational Cancer Institute2021 to 2023$1,424,613December 6, 2018November 30, 2024LEE, JEONGWUreporter.nih.gov
KSHVmediated regulation of proline metabolismNIHNational Institute of Dental & Craniofacial Research2021 to 2023$1,404,235September 23, 2020November 30, 2024JUNG, JAE Ureporter.nih.gov
Forward genetic analysis of biliary system formationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,402,632July 25, 2015April 30, 2027SAKAGUCHI, TAKUYAreporter.nih.gov
Toward Selective Androgen Deprivation by Targeting Androgen Activation of SRFNIHNational Cancer Institute2021 to 2024$1,383,201June 19, 2014December 31, 2024HEEMERS, HANNELOREreporter.nih.gov
KSHV-mediated metabolic reprogramming for LANA expression and viral persistencyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,350,832June 14, 2024April 30, 2029JUNG, JAE Ureporter.nih.gov
Mechanisms of Airway Epithelial Barrier Dysfunction by Respiratory Syncytial Virus and Environmental StimuliNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,319,730July 1, 2019June 30, 2025REZAEE, FARIBAreporter.nih.gov
Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes - (ARMMS-T2D)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022$1,308,257July 4, 2017June 30, 2025KIRWAN, JOHN P.reporter.nih.gov
Nitric oxide induced soluble guanylate cyclase dysfunction or activation: Implications as a disease indicator or in therapyNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,284,685September 15, 2023June 30, 2025GHOSH, ARNABreporter.nih.gov
Role of TLR2 in angiogenesisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,282,712February 1, 2019January 31, 2025BYZOVA, TATIANA Vreporter.nih.gov
Calcium imaging-based insights and guidance of deep brain stimulation to enhance chronic, post-stroke rehabilitation in a rodent model of ischemiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,268,198August 1, 2024July 31, 2029DANA, HOD MICHAELreporter.nih.gov
The I-SCORE (Intensive Stroke Cycling for Optimal Recovery and Economic value) TrialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,262,929April 1, 2024February 28, 2029LINDER, SUSAN MARIEreporter.nih.gov
7/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,262,779September 25, 2017May 31, 2028POGGIO, EMILIO DANIELreporter.nih.gov
Interplay between LINE-1 retrotransposons, condensins, and IFNNIHNational Institute of General Medical Sciences2023 to 2025$1,232,851June 1, 2023February 28, 2027LONGWORTH, MICHELLE Sreporter.nih.gov
tPA nanoconjugate for stroke therapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,227,994September 30, 2019July 31, 2025LABHASETWAR, VINOD Dreporter.nih.gov
The Interplay between Genetics and Aerobic Exercise to Slow Parkinson's disease (GEARS) TrialNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,210,130January 18, 2024December 31, 2028ALBERTS, JAY L.reporter.nih.gov
The role of TRAF4 E3 ligase in IL-25-mediated allergic asthmaNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,207,500March 1, 2020February 28, 2025LIU, CAINIreporter.nih.gov
The Untranslated 3'End of SARS-CoV-2 RNA as a Determinant of Obesity-Accelerated InfectivityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,207,500September 14, 2021August 31, 2025FOX, PAUL Lreporter.nih.gov
Immune Function in Sepsis: Role of SirtuinNIHNational Institute of General Medical Sciences2023 to 2025$1,207,500May 1, 2023February 29, 2028VACHHARAJANI, VIDULAreporter.nih.gov
Multimodal single-cell genomic and epigenomic analyses elucidate Alzheimer’s sexual dimorphism in human immune systems agingNIHNational Institute on Aging2021$1,205,802September 5, 2021August 31, 2023CHENG, FEIXIONGreporter.nih.gov
Sema3C Signaling as an Alternative Activator of Canonical Wnt Signaling in GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,195,425April 1, 2023March 31, 2028YU, JENNIFER Sreporter.nih.gov
Spatiotemporal Coding in the Pain Circuit Along the Spine-brain ContinuumNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,164,262September 15, 2018November 30, 2023SAAB, CARL Yreporter.nih.gov
Molecular Profiling and Biomarkers of Memory Phenotypes in Temporal Lobe EpilepsyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,155,956July 15, 2024June 30, 2029BUSCH, ROBYN Mreporter.nih.gov
The vital role of T403 phosphorylation of STAT2 in post-viral bacterial pneumoniaNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,127,000March 20, 2024February 28, 2029WANG, YUXINreporter.nih.gov
Development of a first-in-class complement inhibitor for treating complement-mediated hematologic diseasesNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,127,000September 5, 2024July 31, 2026LIN, FENG Creporter.nih.gov
Small Molecule Therapeutic for Heart FailureNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,118,301December 15, 2023November 30, 2025PRASAD, SATHYAMANGLA Vreporter.nih.gov
Treatment of Fentanyl Overdose-Induced Respiratory Failure by Low-Dose DexmedetomidineNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,102,741September 20, 2020August 31, 2025HAOUZI, PHILIPPE Areporter.nih.gov
Macrophage-based Therapy and Immune Checkpoint Blockade for GlioblastomaNIHNational Cancer Institute2023 to 2025$1,086,450December 1, 2022November 30, 2027BAO, SHIDENGreporter.nih.gov
T cell-dependent regulation of microglia demyelinating functionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,056,564March 1, 2019January 31, 2025BERGMANN, CORNELIAreporter.nih.gov
Endocytic Trafficking of ADCs in GBM cancer stem-like cellsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,051,314April 1, 2019March 31, 2024GLADSON, CANDECE Lreporter.nih.gov
Targeting TNFR2 Pathways in Psoriatic DiseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,048,432July 8, 2019December 31, 2024HUSNI, ELAINEreporter.nih.gov
Studying alcohol-associated liver disease and its interaction with rs738409 variant in PNPLA3 in a liver culture modelNIHNational Institute on Alcohol Abuse and Alcoholism2024 to 2025$1,046,954September 25, 2024June 30, 2029WU, XIANFANGreporter.nih.gov
Per-Oral Pyloromyotomy (POP) in the treatment of medical refractory gastroparesis : A randomized, sham-controlled trialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,044,209July 15, 2020March 31, 2026ALLEMANG, MATTHEW THOMASreporter.nih.gov
Coordinate control of hemeprotein maturation and function by cell chaperones, heme, and nitric oxideNIHNational Institute of General Medical Sciences2021 to 2022$1,042,456September 1, 2019June 30, 2024STUEHR, DENNIS Jreporter.nih.gov
Developing hemophilia A therapeutics by targeting translational and posttranslational regulation of FVIIINIHNational Heart, Lung, and Blood Institute2024 to 2025$1,036,148March 15, 2024January 31, 2028ZHANG, BINreporter.nih.gov
Vista, A Novel Checkpoint that Suppresses Anti-Tumor T Cell ResponsesNIHNational Cancer Institute2021 to 2023$1,028,770September 1, 2012December 31, 2024WANG, LI LILYreporter.nih.gov
Activation of the beta-3 integrins: Role of the KindlinsNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,023,294July 1, 2009March 31, 2023PLOW, EDWARD FRANKLINreporter.nih.gov
Stimulating Retina Regeneration from Muller Cells in Progressive Retinal DegenerationsNIHNational Eye Institute2021 to 2022$1,020,271May 1, 2020March 31, 2024PERKINS, BRIAN Dreporter.nih.gov
Actin methylation as a novel mechanism that regulates gut barrier integrity and repairNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,011,436January 15, 2024December 31, 2028IVANOV, ANDREI IVANOVICHreporter.nih.gov
The effect of nucleosomes on the earliest stages of RNA polymerase II transcriptionNIHNational Institute of General Medical Sciences2021 to 2025$969,326September 1, 2018May 31, 2028LUSE, DONALreporter.nih.gov
Functional consequences of mutations in spliceosomal small nuclear RNAsNIHNational Institute of General Medical Sciences2021 to 2022$968,639August 1, 2019July 31, 2024PADGETT, RICHARD Areporter.nih.gov
Epithelial cytokeratins control corneal inflammation through intrinsic mechanismsNIHNational Eye Institute2021 to 2022$967,876September 1, 2019June 30, 2024TAM, K. P. CONNIEreporter.nih.gov
Cerebellar deep brain stimulation to enhance chronic post-stroke rehabilitationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$958,678March 1, 2018February 29, 2024BAKER, KENNETH Breporter.nih.gov
Towards Generating a Multimodal and Multivariate Classification Model from Imaging and Non-Imaging Measures for Accurate Diagnosis and Monitoring of Dementia in Parkinsons disease.NIHNational Institute of Neurological Disorders and Stroke2021 to 2022$956,383September 1, 2020September 30, 2022MISHRA, VIRENDRA Rreporter.nih.gov
The UroMonitor: Innovative Technology to Improve Management of Bladder DysfunctionNIHNational Institute of Biomedical Imaging and Bioengineering2021$948,822September 1, 2021August 31, 2024DAMASER, MARGOT S.reporter.nih.gov
Complement in Paclitaxel-induced peripheral neuropathyNIHNational Cancer Institute2021 to 2024$936,532March 5, 2020February 28, 2026XU, JIJUNreporter.nih.gov
Deciphering the Roles of STING-Mediated T cell Pyroptosis in Antitumor ImmunityNIHNational Cancer Institute2024 to 2025$935,004July 1, 2024June 30, 2029WU, JIANJUNreporter.nih.gov
Multisite phosphorylated S6K1 directs a regulatory module determining adipocyte lipid metabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$934,980April 9, 2020January 31, 2024FOX, PAUL Lreporter.nih.gov
Mechanisms of Vision Loss in X-Linked Juvenile RetinoschisisNIHNational Eye Institute2021 to 2022$933,720March 1, 2019February 29, 2024PEACHEY, NEAL S.reporter.nih.gov
Role of sulfide in oral microbiota-host interactions that promote periodontitisNIHNational Institute of Dental & Craniofacial Research2023 to 2025$908,000December 1, 2022November 30, 2025STACY, APOLLOreporter.nih.gov
Unconventional myosins and the regulation of gut barrier integrity and restitution during inflammationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$905,274September 15, 2020July 31, 2024IVANOV, ANDREI IVANOVICHreporter.nih.gov
Mechanisms of HIF1 alpha mediated dysregulated skeletal muscle proteostasis in alcoholic liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$895,645March 1, 2021February 28, 2027WELCH, NICOLEreporter.nih.gov
Specific-sized hyaluronan: a dual targeted therapy for ALDNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$880,703August 1, 2018July 31, 2025NAGY, LAURA E.reporter.nih.gov
1/2 Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial HypertensionNIHNational Heart, Lung, and Blood Institute2025$873,890September 1, 2024August 31, 2030HERESI DAVILA, GUSTAVO ADOLFOreporter.nih.gov
CDK6-dependent metabolic reprogramming in KSHV pathogenesisNIHNational Institute of Dental & Craniofacial Research2024 to 2025$870,741September 1, 2024May 31, 2029ZHAO, JUNreporter.nih.gov
Deciphering MDSC function for GBM targetingNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$869,874April 1, 2019March 31, 2025LATHIA, JUSTIN D.reporter.nih.gov
Mechanistic basis of exercise responses in liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$862,548September 1, 2023July 31, 2027DASARATHY, SRINIVASANreporter.nih.gov
Vitamin D and Photodynamic Therapy for Human Skin Cancer (SCC and BCC)NIHNational Cancer Institute2021 to 2022$842,361December 27, 2016November 30, 2022MAYTIN, EDWARD Vreporter.nih.gov
Supporting pregnant patients as they face a changing landscape of prenatal genetic tests and post-diagnosis optionsNIHNational Human Genome Research Institute2024$831,046September 18, 2024August 31, 2025FARRELL, RUTHreporter.nih.gov
Assay Development for Discovery of a Small Molecule Inhibitor of a Novel Metabolic Pathway that Drives ObesityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$805,000March 1, 2020December 31, 2023FOX, PAUL Lreporter.nih.gov
ER-to-Golgi transport of coagulation factors V and VIIINIHNational Heart, Lung, and Blood Institute2021 to 2022$805,000December 26, 2008June 30, 2024ZHANG, BINreporter.nih.gov
Lymphatic dysfunction in neurodevelopmental disorders and associated behaviorsNIHNational Institute of Mental Health2023 to 2024$805,000September 1, 2023December 15, 2024LOUVEAU, ANTOINEreporter.nih.gov
Molecular mechanism of Zika virus-induced premature craniofacial suture closureNIHNational Institute of Dental & Craniofacial Research2024 to 2025$805,000January 1, 2024December 31, 2028CHEN, WEIQIANGreporter.nih.gov
Aberrant tumor metabolism that enables AR antagonist-resistant prostate cancerNIHNational Cancer Institute2021 to 2023$802,660December 1, 2019June 9, 2023SHARIFI, NIMAreporter.nih.gov
A Multimodal, Multiscale and Multistage Systems Biology (M3SB) Infrastructure for Precision Medicine in Alzheimer’s Disease and LongevityNIHNational Institute on Aging2025$802,034June 1, 2025February 28, 2030CHENG, FEIXIONGreporter.nih.gov
Artificial sweeteners and cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2025$796,395March 4, 2025December 31, 2028HAZEN, STANLEY Lreporter.nih.gov
Targeting macrophage reprogramming in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$793,965September 1, 2023August 31, 2028CHEN, PEIWENreporter.nih.gov
Mechanism and therapeutic potential of microglia regulation in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$792,925September 1, 2022July 31, 2027CHEN, PEIWENreporter.nih.gov
Understanding the full spectrum of epigenetic vulnerability in cancer through the delineation of DNA methylation function in gene 3' endNIHNational Cancer Institute2021 to 2022$790,332February 1, 2019December 30, 2022TING, ANGELA Hreporter.nih.gov
Demonstrating the Feasibility of Democratized Push-Button Autonomous Cardiac MRI exam in Community Family Health Centers (AutoCMR for FHC)NIHNational Heart, Lung, and Blood Institute2025$783,801September 3, 2025May 31, 2029NGUYEN, CHRISTOPHER Treporter.nih.gov
The Role of Bacterial Choline Metabolism in Host Stress ResponsesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$783,358June 1, 2019March 31, 2024BROWN, JONATHAN MARKreporter.nih.gov
A novel regulator of corneal wound healing and Pseudomonas aeruginosa keratitisNIHNational Eye Institute2021 to 2022$780,850April 1, 2019March 31, 2024LIN, FENG Creporter.nih.gov
Broad Bandwidth Transducers for High Resolution Information Rich IVUSNIHNational Heart, Lung, and Blood Institute2022 to 2023$760,655June 10, 2022April 30, 2024FLEISCHMAN, AARON Jreporter.nih.gov
Elucidating a novel molecular biomarker for castration-resistant prostate cancerNIHNational Cancer Institute2021 to 2022$757,103April 1, 2018March 31, 2023SHARIFI, NIMAreporter.nih.gov
Targeting ZDHHC13-activated palmitoylation for melanoma treatmentNIHNational Cancer Institute2021 to 2023$746,997July 1, 2019June 30, 2024CHEN, SHUYANGreporter.nih.gov
Molecular regulatory mechanism of Zika virus-induced intracranial calcificationsNIHNational Institute of Dental & Craniofacial Research2022 to 2024$746,997May 1, 2022April 30, 2025CHEN, WEIQIANGreporter.nih.gov
Determining the Immunological Consequences of DNA Replication Stress Response Defects in Renal Cells Carcinoma to Improve Immunotherapy OutcomesNIHNational Cancer Institute2022 to 2024$746,997July 3, 2019July 31, 2025MCGRAIL, DANIEL JAMESreporter.nih.gov
ASC oligomerization and transmission as an initiating event for protein aggregation in Synucleinopathy DementiasNIHNational Institute on Aging2022 to 2024$746,997September 1, 2022August 31, 2025PANICKER, NIKHILreporter.nih.gov
Developing next generation multiphoton systems to reveal cortico-thalamic interactions underlying short-term memory in behaving miceNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2024$746,997September 1, 2022May 31, 2025YILDIRIM, MURATreporter.nih.gov
Deamidation-mediated metabolic reprogramming by KSHV in cell proliferation and tumorigenesisNIHNational Institute of Dental & Craniofacial Research2021 to 2023$746,646July 1, 2021June 30, 2025ZHAO, JUNreporter.nih.gov
Development of a Miniaturized, Pediatric Continuous-Flow Total Artificial Heart with a Single Moving PartNIHNational Heart, Lung, and Blood Institute2021$746,410April 1, 2018February 28, 2023FUKAMACHI, KIYOTAKAreporter.nih.gov
Master - 2/2 Empaglifozin To Improve Right Ventricular Function in Pulmonary Arterial HypertensionNIHNational Heart, Lung, and Blood Institute2024 to 2025$746,327September 1, 2024August 31, 2030GASSMAN, JENNIFER Jreporter.nih.gov
The role of PDK4 in alcohol-associated liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$744,213September 22, 2021August 31, 2026WU, JIANGUOreporter.nih.gov
Gut Microbe-Derived Lipids Shape Chronic Inflammation in Cardiometabolic DiseaseNIHNational Heart, Lung, and Blood Institute2025$743,302May 1, 2025February 28, 2029BROWN, JONATHAN MARKreporter.nih.gov
Mitochondrial Mechanisms in AsthmaNIHNational Heart, Lung, and Blood Institute2025$732,225August 1, 2025April 30, 2030ERZURUM, SERPIL C.reporter.nih.gov
Repurposing Siponimod for Alzheimer's DiseaseNIHNational Institute on Aging2021$731,856August 15, 2021October 15, 2021SABBAGH, MARWAN NOELreporter.nih.gov
A Nomogram to Predict Seizure Outcomes after Resective Epilepsy SurgeryNIHNational Institute of Neurological Disorders and Stroke2021$728,061May 15, 2017April 30, 2023JEHI, LARAreporter.nih.gov
Homologous recombination repair pathway mutations and genetic mechanisms shaping anti-tumor immunity and immunotherapy efficacyNIHNational Cancer Institute2025$713,601August 1, 2025July 31, 2030CHAN, TIMOTHY AN-THYreporter.nih.gov
Personalized vasopressor therapy in patients with septic shockNIHNational Institute of General Medical Sciences2022 to 2025$708,473September 1, 2022August 31, 2027BAUER, SETHreporter.nih.gov
Prognosis and Predictors of ACL Reconstruction: A Multicenter Cohort StudyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$703,753September 22, 2006September 15, 2024SPINDLER, KURT PAULreporter.nih.gov
Genetic Dissection of Stress Responses in Shwachman-Diamond SyndromeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$701,158June 22, 2023May 31, 2026COREY, SETH JOELreporter.nih.gov
Matrix Regenerative Nanotherapeutic Platform for Pelvic Organ ProlapseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$688,436September 1, 2025August 31, 2030DAMASER, MARGOT S.reporter.nih.gov
Impact of early-life pathogen exposures on pre-erythrocytic malaria vaccine effectiveness in Kenyan infantsNIHNational Institute of Allergy and Infectious Diseases2025$682,200August 22, 2025July 31, 2030DOBBS, KATHERINE ROSEreporter.nih.gov
Novel Cardiac MRI-Based Predictors for Tetralogy of Fallot: Deformation, Kinematic, and Geometric AnalysesNIHNational Heart, Lung, and Blood Institute2022 to 2025$677,485February 15, 2021January 31, 2027TANDON, ANIMESHreporter.nih.gov
Modeling Transition Metal Ion Binding to ProteinsNIHNational Institute of General Medical Sciences2024 to 2025$674,546September 1, 2019July 31, 2028MERZ, KENNETH M.reporter.nih.gov
Parent-Mediated Teleheath Intervention for Insomnia in Young Autistic ChildrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$668,178September 1, 2025August 31, 2030JOHNSON, CYNTHIA Rreporter.nih.gov
Neural Mechanisms underlying the benefits of Aerobic Exercise in Advanced Parkinson's diseaseNIHNational Institute on Aging2025$665,118September 15, 2025August 31, 2030ALBERTS, JAY L.reporter.nih.gov
Platelets in CancerNIHNational Heart, Lung, and Blood Institute2021$663,334July 15, 2018June 30, 2024BYZOVA, TATIANA Vreporter.nih.gov
Translational science specialist in genitourinary cancersNIHNational Cancer Institute2021 to 2024$662,140August 13, 2020July 31, 2025BERK, MICHAEL P.reporter.nih.gov
The role of HMGB1 in the lung response to bacterial injuryNIHNational Heart, Lung, and Blood Institute2025$656,988August 1, 2025April 30, 2030MESSER, JEANNETTE SOPHIAreporter.nih.gov
Investigating the Role of VISTA in Driving Immune Evasion in Acute Myeloid LeukemiaNIHNational Cancer Institute2025$654,837September 22, 2025June 30, 2030WANG, LI LILYreporter.nih.gov
Modulation of Protective RAS-GPCR Pathways in Aortic DiseaseNIHNational Heart, Lung, and Blood Institute2021$647,156May 1, 2018April 30, 2024KARNIK, SADASHIVA Sreporter.nih.gov
Microbial metabolites and Innate Immunity in AH: Biomarkers of injury and repairNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$641,557September 22, 2018December 31, 2024NAGY, LAURA E.reporter.nih.gov
MR Fingerprinting for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2025$639,800January 15, 2019March 31, 2030WANG, ZHONG IRENEreporter.nih.gov
Assessment of lenalidomide to treat Alzheimer's diseaseNIHNational Institute on Aging2021$639,729September 1, 2018October 15, 2021SABBAGH, MARWAN NOELreporter.nih.gov
Mitochondria in cardiomyocyte-fibroblast transcellular cross-talkNIHNational Heart, Lung, and Blood Institute2025$639,621May 15, 2025March 31, 2029PRASAD, SATHYAMANGLA Vreporter.nih.gov
Role of SMARCA5 in GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2025$638,697July 15, 2025June 30, 2030YU, JENNIFER Sreporter.nih.gov
Improving sarcoidosis patients’ care with a collaboratively developed, patient centered programNIHNational Institute on Minority Health and Health Disparities2022 to 2025$638,620July 15, 2022March 31, 2027HARPER, LOGANreporter.nih.gov
Pain avoidance behavior and its relation to risk for opioid use in chronic pain patientsNIHNational Institute on Drug Abuse2021 to 2024$629,848August 15, 2020July 31, 2025GOPALAKRISHNAN, RAGHAVANreporter.nih.gov
A SkeleTal muscle Recovery Intervention with Dietary protein in Heart Failure (ASTRID-HF)NIHNational Heart, Lung, and Blood Institute2024 to 2025$626,725March 15, 2023January 31, 2027VEST, AMANDA RUTHreporter.nih.gov
Improving colorectal cancer screening decisions through consideration of life expectancyNIHNational Institute on Aging2025$625,452January 1, 2025December 31, 2029MARTINEZ, KATHRYN ANNEreporter.nih.gov
Remodeling host immunity in oral cancer with personalized RNA nanoparticle vaccinesNIHNational Institute of Dental & Craniofacial Research2021 to 2024$621,216January 12, 2022June 30, 2025SILVER, NATALIE LEAreporter.nih.gov
Novel role of integrins in paracrine regulation of vasculatureNIHNational Heart, Lung, and Blood Institute2021$617,218July 14, 2003June 30, 2024BYZOVA, TATIANA Vreporter.nih.gov
A Cognitive Risk Calculator and Screening tool for Primary Care SettingsNIHNational Institute on Aging2021$615,414September 30, 2020August 31, 2022FLODEN, DARLENEreporter.nih.gov
Protective factors in diabetic kidney disease in patients with type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023$606,740January 1, 2023December 31, 2025CARAMORI, MARIA LUIZA Areporter.nih.gov
Integrin regulation of vascular function in Alzheimer's diseaseNIHNational Institute on Aging2023$605,489September 1, 2023August 31, 2025LOUVEAU, ANTOINEreporter.nih.gov
Alcohol and gut-brain axis and the role of butyrate on neuroinflammation and pain sensitivityNIHNational Institute on Alcohol Abuse and Alcoholism2025$601,129September 25, 2025June 30, 2030CRESCI, GAIL ANNreporter.nih.gov
Developing a Donor-Candidate Risk Prediction System to Optimize Lung Allocation and Transplant OutcomesNIHNational Heart, Lung, and Blood Institute2022 to 2025$598,206April 1, 2022March 31, 2027LEHR, CARLI JESSICAreporter.nih.gov
Sarcopenia in cirrhosis is mediated by a hyperammonemic stress responseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$579,497August 1, 2018April 30, 2025DASARATHY, SRINIVASANreporter.nih.gov
Role of melanopsin in outer segment renewalNIHNational Eye Institute2025$574,158September 1, 2025April 30, 2030RAO, SUJATAreporter.nih.gov
Assessing feasibility of gastric cancer screening in the USNIHNational Cancer Institute2025$564,414April 1, 2025March 31, 2030KIM, MICHELLE KANGreporter.nih.gov
Neural Coding and Control of Pain Detection in Somatosensory CortexNIHNational Institute of Neurological Disorders and Stroke2025$560,934April 1, 2025March 31, 2030SAAB, CARL Yreporter.nih.gov
Precision Medicine Digital Twins for Alzheimer’s Target and Drug Discovery and LongevityNIHNational Institute on Aging2025$552,045August 15, 2023August 31, 2028CHENG, FEIXIONGreporter.nih.gov
Automated Arthroscopic Partial Meniscectomy Patient Outcome Prediction using Deep LearningNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$544,570July 1, 2022June 30, 2027YANG, MINGRUIreporter.nih.gov
Improving Adherence with Statins Through Use of the Statin Choice Decision AidNIHNational Heart, Lung, and Blood Institute2022$535,354September 19, 2022February 29, 2024MARTINEZ, KATHRYN ANNEreporter.nih.gov
Host Regulation of Flavivirus InfectionNIHNational Institute of Allergy and Infectious Diseases2025$530,385June 6, 2025May 31, 2030GACK, MICHAELA ULRIKEreporter.nih.gov
Quadrupole Time-of-Flight LC-MSNIHOffice of the Director, National Institutes of Health2021$529,999April 15, 2021April 14, 2022WILLARD, BELINDA BELLEreporter.nih.gov
Impact of Disparities Affecting Survival among Advanced Heart Failure Patients and Transplant RecipientsNIHNational Heart, Lung, and Blood Institute2021$526,607April 1, 2018January 31, 2023HSICH, EILEEN MICHELLEreporter.nih.gov
Alcoholic Hepatitis Consortia: an intramural/extramural collaboration to unravel genetic determinantsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$509,026September 20, 2017August 31, 2023NAGY, LAURA E.reporter.nih.gov
Deep cerebellar electrical stimulation for post-stroke motor recoveryNIHNational Institute of Neurological Disorders and Stroke2021$507,787September 30, 2016June 30, 2023MACHADO, ANDRE GUELMANreporter.nih.gov
Effect of Lipids on Vascular Graft HealingNIHNational Heart, Lung, and Blood Institute2021$503,544August 1, 2000November 30, 2022GRAHAM, LINDA Mreporter.nih.gov
Regulation and Function of Oral Resident Memory T CellsNIHNational Institute of Dental & Craniofacial Research2023 to 2024$498,000September 1, 2023August 31, 2025STOLLEY, JAMES MICHAELreporter.nih.gov
Modifiable Determinants of Disparities in Multiple Myeloma Treatment PatternsNIHNational Cancer Institute2024 to 2025$497,998February 1, 2024January 31, 2027GASOYAN, HAMLETreporter.nih.gov
Exploring palmitoylation dynamics: impacts on Cadherin-Catenin adhesion and lipid metabolism in the progression of melanoma lung metastasisNIHNational Cancer Institute2025$487,468September 1, 2025August 31, 2030CHEN, SHUYANGreporter.nih.gov
Defining role of Long non-coding RNA (LncRNA) Gm15417 in iNKT development and subset differentiationNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$486,732May 2, 2022April 30, 2025BASU, JAYATIreporter.nih.gov
Chromatin Modifier Gene Mutation and Enhancer Dysfunction in Bladder CancerNIHNational Cancer Institute2021 to 2022$486,410March 1, 2019January 16, 2023LEE, BYRON Hreporter.nih.gov
Personalizing Preoperative Stress Testing Using Machine LearningNIHNational Heart, Lung, and Blood Institute2021 to 2023$483,141January 15, 2019June 30, 2024PAPPAS, MATTHEWreporter.nih.gov
Precision Medicine Digital Twins for Alzheimer’s Target and Drug Discovery and LongevityNIHNational Institute on Aging2023$482,520August 15, 2023August 14, 2025CHENG, FEIXIONGreporter.nih.gov
Endogenous synthesis of TRAIL by glioma cancer stem cells and resistance to TRAIL therapyNIHNational Institute of Neurological Disorders and Stroke2023$478,001September 18, 2023August 31, 2025GLADSON, CANDECE Lreporter.nih.gov
Quantitative Susceptibility Mapping of Brain Iron in People with HIV: Mechanistic Links to Neuropsychiatric DisordersNIHNational Institute of Mental Health2023 to 2024$475,489August 1, 2023May 31, 2026KALLIANPUR, ASHA Rreporter.nih.gov
Integrative analysis of proteomics and transcriptomics to delineate vesicular transport related protein abnormalities related to Alzheimer's, Lewy body and mixed PathologiesNIHNational Institute on Aging2022$455,583June 1, 2022May 31, 2025PILLAI, JAGAN AYYAPPANreporter.nih.gov
Identifying the patient, disease, surgical, and implant positional shift factors that predict outcomes following total shoulder arthroplastyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$443,449April 1, 2020March 31, 2024RICCHETTI, ERIC T.reporter.nih.gov
Antiviral role of Condensin IINIHNational Institute of Allergy and Infectious Diseases2021 to 2022$442,750March 4, 2021February 29, 2024LONGWORTH, MICHELLE Sreporter.nih.gov
Integrin mediated regulation of lymphatics during aging and neurodegenerationNIHNational Institute on Aging2022$442,750May 15, 2022April 30, 2024LOUVEAU, ANTOINEreporter.nih.gov
Molecular correlates of sub-regional thalamic degeneration in multiple sclerosisNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$442,750February 1, 2022January 31, 2025DUTTA, RANJANreporter.nih.gov
The impact of exercise on subthalamic nucleus neural activity in Parkinson's diseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$442,750August 15, 2022July 31, 2025ALBERTS, JAY L.reporter.nih.gov
Targeting and Stimulating Cortical Area 3a to Restore ProprioceptionNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$442,750May 15, 2023April 30, 2026TAYLOR, DAWN MARIEreporter.nih.gov
Investigation of discrete neurodegenerative changes of the in vivo multiple sclerosis spinal cord using 7T MRINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$442,750July 18, 2024June 30, 2026MAHAJAN, KEDARreporter.nih.gov
Role of nitrate in microbiota ecologyNIHNational Institute of General Medical Sciences2025$442,750August 15, 2025April 30, 2030STACY, APOLLOreporter.nih.gov
Induce and Image extrachromosomal DNA in human glioblastoma avatarNIHNational Institute of Neurological Disorders and Stroke2025$442,750August 1, 2025July 31, 2027XIE, LIANGQIreporter.nih.gov
Systematic identification of drivers controlling Fusobacterium and oral squamous cell carcinoma interactionsNIHNational Institute of Dental & Craniofacial Research2025$442,750July 1, 2025June 30, 2027MCGRAIL, DANIEL JAMESreporter.nih.gov
A Pathomimetic Gingiva-on-a-Chip for Assessing Microbiota-Directed Anti-Inflammatory TherapeuticsNIHNational Institute of Dental & Craniofacial Research2025$442,750August 14, 2025August 13, 2027STACY, APOLLOreporter.nih.gov
Degradomics of proteolytic mechanisms in post-traumatic osteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$434,682August 22, 2025June 30, 2030APTE, SUNEEL Sreporter.nih.gov
Failure with Continuity and Its Relation to Rotator Cuff Repair Clinical OutcomesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$433,919April 1, 2016January 31, 2022DERWIN, KATHLEEN ANNEreporter.nih.gov
1/2 Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial HypertensionNIHNational Heart, Lung, and Blood Institute2024$433,123September 1, 2024August 31, 2025HERESI DAVILA, GUSTAVO ADOLFOreporter.nih.gov
CYP17A1-independent androgen synthesis and prostate cancer resistance to next-generation hormonal therapyNIHNational Cancer Institute2022 to 2023$432,123February 1, 2022June 9, 2023SHARIFI, NIMAreporter.nih.gov
Molecular Mechanism of Glucocorticoid Receptor, Cytochrome P450, and P-Glycoprotein Axis on Drug Regulation at the Blood-Brain Barrier in Epilepsy with Focal Cortical DysplasiaNIHNational Institute of Neurological Disorders and Stroke2025$431,676December 6, 2024November 30, 2029GHOSH, CHAITALIreporter.nih.gov
Immunogenomics platform for the analysis of cancerNIHNational Cancer Institute2024 to 2025$425,134September 13, 2024August 31, 2029MAKAROV, VLADIMIRreporter.nih.gov
Transcriptional regulation of MyelopoiesisNIHNational Heart, Lung, and Blood Institute2024$421,799July 15, 2024November 30, 2024BASU, JAYATIreporter.nih.gov
Cilia Assembly and Transport in Photoreceptor CellsNIHNational Eye Institute2021$421,194August 1, 2006June 30, 2023PERKINS, BRIAN Dreporter.nih.gov
The pathogenic roles of GSDMD-dependent gut epithelium extracellular vesicles in IBDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$420,472April 8, 2021November 30, 2021PIZARRO, THERESA TORRESreporter.nih.gov
Gender and AsthmaNIHNational Heart, Lung, and Blood Institute2023$419,061January 1, 2023June 27, 2023ZEIN, JOEreporter.nih.gov
Elucidating genetics of response to immune checkpoint blockade in lung cancerNIHNational Cancer Institute2021$418,751January 18, 2017December 31, 2022CHAN, TIMOTHY AN-THYreporter.nih.gov
Forging a new path with cyclin-dependent kinase inhibitors to treat epithelioid hemangioendotheliomaNIHNational Cancer Institute2024 to 2025$413,972February 1, 2024January 31, 2026RUBIN, BRIAN Preporter.nih.gov
Targeting NEK2 to potentiate standard of care therapies for breast cancerNIHNational Cancer Institute2024 to 2025$413,972February 1, 2024January 31, 2026KERI, RUTH A.reporter.nih.gov
Investigating a Novel Inhibitory Receptor in Regulating CAR-T Cell Persistence and FunctionNIHNational Cancer Institute2024$413,971July 8, 2024June 30, 2026WANG, LI LILYreporter.nih.gov
Characterization of sarcopenia in heart failure by T1rho magnetic resonance fingerprintingNIHNational Institute on Aging2022 to 2024$412,244July 15, 2022August 2, 2024ECK, BRENDAN LEEreporter.nih.gov
Elucidating and Leveraging the mTOR Negative Feedback Pathway in Breast CancerNIHNational Cancer Institute2021$410,801August 1, 2017July 31, 2023KERI, RUTH A.reporter.nih.gov
Hyperthermic Intraperitoneal Chemotherapy Mechanisms in Epithelial Ovarian CancerNIHNational Cancer Institute2021 to 2022$410,209June 1, 2021May 31, 2023REIZES, OFERreporter.nih.gov
The Roles of a Novel Immune-Checkpoint Receptor Complex in Driving T Cell Dysfunction in CancerNIHNational Cancer Institute2022 to 2023$409,455February 8, 2022January 31, 2024WANG, LI LILYreporter.nih.gov
Operationalizing DNMT1-Targeting to Treat Chemorefractory Pancreatic CancerNIHNational Cancer Institute2022 to 2023$409,455March 1, 2022February 28, 2025SAUNTHARARAJAH, YOGENreporter.nih.gov
Cancer-specific metabolites as cues to engineer and target anti-tumor therapeutic bacteriaNIHNational Cancer Institute2022 to 2023$409,455August 1, 2022July 31, 2025DWIDAR, MOHAMMEDreporter.nih.gov
ANTIVIRAL MECHANISMS OF 2-5A-DEPENDENT RNASE LNIHNational Institute of Allergy and Infectious Diseases2021$402,500September 25, 2017August 31, 2023SILVERMAN, ROBERT H.reporter.nih.gov
Impact of microfibril turnover on vascular development and diseaseNIHNational Heart, Lung, and Blood Institute2022$402,500December 1, 2021July 31, 2022MEAD, TIMOTHY JOSEPHreporter.nih.gov
The vital role of T404 phosphorylation of STAT2 in post-viral bacterial pneumoniaNIHNational Heart, Lung, and Blood Institute2022$402,500September 1, 2022August 31, 2024WANG, YUXINreporter.nih.gov
Synthetic biology tools and strategies to streamline the sensing and responding to disease cues in engineered theragnostic bacteria.NIHNational Institute of General Medical Sciences2025$402,500January 1, 2025November 30, 2029DWIDAR, MOHAMMEDreporter.nih.gov
The role of protein O-GlcNAcylation in regulating keratinocyte function in skin fibrosisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023$401,433September 23, 2023August 31, 2025WANG, YANreporter.nih.gov
Microbiome-Mediated Tumor Immunomodulation in a Pathomimetic Colorectal Cancer ChipNIHNational Cancer Institute2025$400,890March 1, 2025February 28, 2028KIM, HYUN JUNGreporter.nih.gov
Giving and Taking Away: Mapping Ethical Recommendations for Addressing Emotional Retraumatization in Bionics ResearchNIHNational Institute of Biomedical Imaging and Bioengineering2025$398,466September 15, 2025September 14, 2027MARASCO, PAUL D.reporter.nih.gov
Effector functions and cellular targets of pathogenic plasmacytoid cells in lupus.NIHNational Institute of Allergy and Infectious Diseases2021$396,250December 1, 2016November 30, 2022JORGENSEN, TRINE NORGAARDreporter.nih.gov
RPE, aging and age-related macular degeneration: the role of oxidative stressNIHNational Eye Institute2021$390,425September 1, 2017May 31, 2022BONILHA, VERA Lreporter.nih.gov
The proteolytic landscape of osteoarthritic cartilageNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$389,620April 10, 2022March 31, 2025APTE, SUNEEL Sreporter.nih.gov
Broad Bandwidth Transducers for High Resolution Information Rich IVUSNIHNational Heart, Lung, and Blood Institute2024$388,924June 10, 2022April 30, 2026FLEISCHMAN, AARON Jreporter.nih.gov
Role of CD6 in the pathogenesis of autoimmune uveitisNIHNational Eye Institute2021$384,362February 1, 2017January 31, 2023LIN, FENG Creporter.nih.gov
Variation in Humeral Head Bone Marrow Characteristics and Their Associations with Rotator Cuff Repair HealingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$382,212September 24, 2021August 31, 2023DERWIN, KATHLEEN ANNEreporter.nih.gov
Thalamic MRI, histopathologic, and clinical correlations in multiple sclerosisNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$368,522September 15, 2018June 30, 2024MAHAJAN, KEDARreporter.nih.gov
Molecular mediators of disparate outcomes experienced by patients of African ancestry with lung cancerNIHNational Cancer Institute2025$368,288December 4, 2024November 30, 2029MCGRAIL, DANIEL JAMESreporter.nih.gov
Evaluating Whether Treating Elevated Blood Pressure in the Inpatient Setting Impacts Patient Outcomes: the ACT-BP pilotNIHNational Heart, Lung, and Blood Institute2025$362,250August 1, 2025July 31, 2027PFOH, ELIZABETH ROSEreporter.nih.gov
Evaluating Over Constraint of the Patella following MPFL Reconstruction as a Contributing Factor to Progressive Cartilage DegradationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$356,213August 1, 2024May 31, 2028ELIAS, JOHN Jreporter.nih.gov
Cytochrome P450-mediated drug interactions at the human blood-brain barrierNIHNational Institute of Neurological Disorders and Stroke2021$345,183April 1, 2017December 31, 2023GHOSH, CHAITALIreporter.nih.gov
Leukotriene B4 and IL-8 in alpha-1 heterozygotes (PI*MZ genotype)NIHNational Heart, Lung, and Blood Institute2024 to 2025$341,121April 1, 2024March 31, 2029TEJWANI, VICKRAMreporter.nih.gov
Role of MLKL in Alcohol-associated Liver DiseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$340,656September 22, 2021August 31, 2023WU, XIAOQINreporter.nih.gov
The impact of antinuclear antibodies on alloimmune responses to renal transplantsNIHNational Institute of Allergy and Infectious Diseases2025$332,690August 1, 2025July 31, 2027VALUJSKIKH, ANNAreporter.nih.gov
Consequences of gain-of-function RPA1 mutations on telomere function and hematopoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$329,056September 15, 2022September 14, 2027SHARMA, RICHAreporter.nih.gov
Improving Access to Lung Transplant Through Broader Geographic SharingNIHNational Heart, Lung, and Blood Institute2021 to 2022$322,748August 1, 2018July 31, 2024TSUANG, WAYNE Mreporter.nih.gov
Developing a clinical and research framework for evaluating inflammation pathway dysregulation in Alzheimer's diseaseNIHNational Institute on Aging2021 to 2022$322,000January 15, 2021December 31, 2023PILLAI, JAGAN AYYAPPANreporter.nih.gov
Integrative analysis of multi-omics data to delineate CCL2 associated inflammatory pathways in Alzheimers DiseaseNIHNational Institute on Aging2021 to 2022$322,000March 15, 2021February 29, 2024PILLAI, JAGAN AYYAPPANreporter.nih.gov
Iron Catalyzed H2S and its Prevalence in Hemolytic and Iron Overload DisordersNIHNational Heart, Lung, and Blood Institute2021$322,000July 1, 2019June 30, 2024HINE, CHRISTOPHER MICHAELreporter.nih.gov
Cleveland Precision Medicine Chronic Kidney Disease CohortNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$300,000September 15, 2017June 30, 2022O'TOOLE, JOHN F.reporter.nih.gov
Effect of RCR healing on degenerative shoulder changes and 5y clinical outcomesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024$293,811September 19, 2024August 31, 2025DERWIN, KATHLEEN ANNEreporter.nih.gov
PD-L1 inhibition promotes type I interferon responses, enhancing chemotherapy-induced cytotoxicity in cancer cellsNIHNational Cancer Institute2021 to 2022$279,799December 14, 2020March 4, 2022CHEON, HYEONJOOreporter.nih.gov
Improving Outcomes in Atrial Fibrillation Through Patient-Centered Decision MakingNIHNational Heart, Lung, and Blood Institute2021 to 2022$278,478May 1, 2018April 30, 2023MARTINEZ, KATHRYN ANNEreporter.nih.gov
Elucidating the mechanisms of intrinsic stem cell resistance to virus infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$275,998September 2, 2019August 5, 2022WU, XIANFANGreporter.nih.gov
Conscious ambulatory bladder monitoring to understand neural control of lower urinary tract functionNIHOffice of the Director, National Institutes of Health2021$274,919February 1, 2017November 30, 2023DAMASER, MARGOT S.reporter.nih.gov
Cole Eye Institute Vision Science Training ProgramNIHNational Eye Institute2021 to 2025$274,512April 1, 2015March 31, 2026ANAND-APTE, BELAreporter.nih.gov
Use of gold-based photothermal nanomaterials for the comminution of kidney stonesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$269,503September 1, 2024August 31, 2029HOULIHAN, IANreporter.nih.gov
Nanoparticle-mediated treatment for bone metastasisNIHNational Cancer Institute2021$268,394May 4, 2016April 30, 2024LABHASETWAR, VINOD Dreporter.nih.gov
Cost-effectiveness and efficacy of a combined intervention to facilitate motor recovery following strokeNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$267,172August 2, 2018January 31, 2024LINDER, SUSAN MARIEreporter.nih.gov
Translating Genetic Risk Factors to Therapies: From Big Data to Druggable TargetsNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$253,497July 1, 2021June 30, 2026SHAW, BENJAMIN C.reporter.nih.gov
Ferroptosis in drug resistant gliomaNIHNational Cancer Institute2025$249,000September 19, 2023August 31, 2028TIEK, DEANNA MARIEreporter.nih.gov
The role of neuronal activity on retinal angiogenesis and blood-retina barrier (BRB) maturationNIHNational Eye Institute2025$248,999May 1, 2025April 30, 2028BISWAS, SAPTARSHIreporter.nih.gov
Developing shared medical appointments for informal caregivers of Alzheimer’s and Dementia patients to improve knowledge, communication, and advanced planningNIHNational Institute on Aging2024 to 2025$247,867August 15, 2024April 30, 2029ALPERT, JORDAN Mreporter.nih.gov
Air Pollution, Environmental Injustice and Progressive Pulmonary FibrosisNIHNational Institute of Environmental Health Sciences2025$241,811January 1, 2025December 31, 2029MACMURDO, MAEVE GEORGIAreporter.nih.gov
Applying Innovative Artificial Intelligence Approaches to a Large Sleep Physiologic Biorepository to Integrate Sleep Disruption in Cardiovascular Risk CalculationNIHNational Heart, Lung, and Blood Institute2023 to 2024$241,500September 1, 2023August 31, 2025LIMA DINIZ ARAUJO, MATHEUSreporter.nih.gov
Restoring The Mechanical Properties of the Respiratory System as a Treatment of Fentanyl Overdose-Induced Hypoventilation using Kappa AgonistsNIHNational Institute on Drug Abuse2023$241,500April 1, 2022March 31, 2025HAOUZI, PHILIPPE Areporter.nih.gov
Lymphatic dysfunction in neurodevelopmental disorders and associated behaviorsNIHNational Institute of Mental Health2025$241,500December 16, 2024November 30, 2029LOUVEAU, ANTOINEreporter.nih.gov
Role of myeloid-derived suppressor cells in local and systemic immunosuppression in glioblastomaNIHNational Cancer Institute2021 to 2022$240,900March 1, 2021February 28, 2023BAYIK WATSON, DEFNEreporter.nih.gov
A Daily, Digital Mindfulness-Based Intervention for Depressive Symptoms After Serious IllnessNIHNational Center for Complementary & Integrative Health2025$240,840August 22, 2025March 31, 2030SIWIK, CHELSEA JANEreporter.nih.gov
Analysis of C9ORF72-associated poly (GR) interactions on BAF chromatin remodeling complex structure and functionNIHNational Institute of Neurological Disorders and Stroke2025$236,668December 15, 2024November 30, 2029LOPEZ GONZALEZ, RODRIGOreporter.nih.gov
Healthy Aging in People with Epilepsy Program (HAP-E): Closing the Gap in Geriatric Epilepsy CareNIHNational Institute of Neurological Disorders and Stroke2025$207,002August 1, 2025July 31, 2030REYES, ANNYreporter.nih.gov
MRI Predictors of Outcome after Arthroscopic Partial MeniscectomyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$206,144August 1, 2019July 31, 2022SUBHAS, NAVEENreporter.nih.gov
MCEMP1 is an adaptor for KIT receptor for mast cell proliferationNIHNational Heart, Lung, and Blood Institute2021 to 2022$203,520April 1, 2021January 22, 2024CHOI, YOUN JUNGreporter.nih.gov
Evaluating the adoption, implementation, and maintenance of a cervical precancer treatment in El SalvadorNIHNational Cancer Institute2025$202,487September 11, 2025August 31, 2027SOLER, MONTSERRATreporter.nih.gov
Unraveling the PTEN Interactome: Modeling Structural and Functional Dynamic Network Architecture for Therapeutic Modulation in Cancer and AutismNIHNational Institute of General Medical Sciences2021 to 2022$200,000July 1, 2021June 30, 2024SMITH, IRIS NIRAreporter.nih.gov
IRF3 activation promotes fibrotic liver injury in alcohol-associated-liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$191,940August 16, 2021April 16, 2024DU ROSS, CHRISTINA KATHERINEreporter.nih.gov
Modulation of Monocyte and T Cell Functions by Immune Inhibitory Receptors during Subclinical MalariaNIHNational Institute of Allergy and Infectious Diseases2025$184,109December 19, 2024November 30, 2026DOBBS, KATHERINE ROSEreporter.nih.gov
Inflammatory Networks Mediating Cognitive Decline In Preclinical Alzheimers DiseaseNIHNational Institute on Aging2021$173,933May 1, 2017April 30, 2024PILLAI, JAGAN AYYAPPANreporter.nih.gov
The Effects of Reduced ACL Stiffness on Dynamic In Vivo Joint FunctionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$167,265July 19, 2019October 21, 2022BEVERIDGE, JILLIAN ELIZABETHreporter.nih.gov
The role of HMGB1 in gut antimicrobial defense and the pathophysiology of inflammatory bowel diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$166,212July 1, 2017June 30, 2023MESSER, JEANNETTE SOPHIAreporter.nih.gov
Matrix-Myosin II Interactions Drive Fibrosis in Idiopathic Pulmonary Fibrosis.NIHNational Heart, Lung, and Blood Institute2021$163,037July 11, 2017June 30, 2023SOUTHERN, BRIAN DERRISreporter.nih.gov
Develop a human liver system to study SLC25A13 mutations in citrin deficiencyNIHNational Center for Advancing Translational Sciences2023$161,000August 1, 2023July 31, 2024WU, XIANFANGreporter.nih.gov
Connexin 43 drives glioblastoma cancer stem cells through a WNK1 signaling axisNIHNational Institute of Neurological Disorders and Stroke2024$161,000August 15, 2024July 31, 2026MULKEARNS-HUBERT, ERIN E.reporter.nih.gov
Metabolic basis of sarcopenia in alcohol-related liver diseaseNIHNational Institute on Alcohol Abuse and Alcoholism2025$161,000September 15, 2025August 31, 2027WELCH, NICOLEreporter.nih.gov
Modifiable Determinants of Disparities in Multiple Myeloma Treatment PatternsNIHNational Cancer Institute2023$160,018February 1, 2023January 31, 2024GASOYAN, HAMLETreporter.nih.gov
Internalization of dead cells governs intestinal stem cell activityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$155,348December 1, 2023November 30, 2026ZHOU, JULIE Y.reporter.nih.gov
Deep Learning of Renal Scans and Kidney Ultrasounds in Children with Antenatal HydronephrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$155,011March 15, 2025January 31, 2030WEAVER, JOHNreporter.nih.gov
Nocturnal hypoxemia dysregulates skeletal muscle protein homeostasis in COPDNIHNational Heart, Lung, and Blood Institute2025$151,578January 1, 2025December 31, 2029ATTAWAY, AMYreporter.nih.gov
The role of retrotransposonable elements in neurodevelopment and diseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$151,040March 1, 2024February 28, 2026TALLEY, MARYreporter.nih.gov
Sex Differences in Blood-Brain and Blood-Tumor Barrier Dynamics in GlioblastomaNIHNational Cancer Institute2022 to 2023$142,152December 10, 2021June 9, 2023SPROWLS, SAMUEL ADAM TYLERreporter.nih.gov
Gender-based precision care for asthmaNIHNational Heart, Lung, and Blood Institute2021$134,136August 7, 2017June 27, 2023ZEIN, JOEreporter.nih.gov
Population Assessments of Aggregate Genetic Risk for DilatedýCardiomyopathyNIHNational Heart, Lung, and Blood Institute2025$133,337August 15, 2021July 31, 2026ARAGAM, KRISHNA Greporter.nih.gov
Platelets as therapeutic and diagnostic entity in fibromuscular dysplasiaNIHNational Heart, Lung, and Blood Institute2025$118,919August 1, 2025June 30, 2027AGGARWAL, ANUreporter.nih.gov
Altered RPE matrix in Sorsby Fundus Dystrophy leads to metabolic dysfunctionNIHNational Eye Institute2021 to 2023$118,363September 10, 2021September 9, 2024GRENELL, ALLISON BROOKEreporter.nih.gov
Immune-Related Adverse Events in Melanoma Patients Receiving Adjuvant Immune Checkpoint Inhibitor TherapyNIHNational Institute of Allergy and Infectious Diseases2025$113,868August 18, 2021July 31, 2026HASSAN, NOHA ABDELWAHAB HASSAN ALIreporter.nih.gov
Polyamines drive glioblastoma progressionNIHNational Cancer Institute2021 to 2023$107,641July 26, 2021April 30, 2024KAY, KRISTENreporter.nih.gov
Host and microbe-dependent mechanisms of enhanced autoimmune susceptibility driven by checkpoint inhibitorsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$107,232December 1, 2023November 30, 2026SALAZAR, VANESSAreporter.nih.gov
Endogenous memory T cell mediated rejection of high-risk cardiac allograftsNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$106,668September 1, 2023August 31, 2025KORITZINSKY, ERIK HARRISONreporter.nih.gov
Characterizing the role of mitochondrial DNA mutations on retinal degeneration.NIHNational Eye Institute2024 to 2025$98,512February 1, 2024January 31, 2027STURGIS, JOHNATHON BRIANreporter.nih.gov
Ribonucleotide Reductase as a Driver of Breast Cancer AggressivenessNIHNational Cancer Institute2024 to 2025$97,932May 1, 2024April 30, 2026BRZOZOWSKI, TAYLOR LYNNreporter.nih.gov
Molecular regulatory mechanism of Zika virus-induced intracranial calcificationsNIHNational Institute of Dental & Craniofacial Research2021$94,042August 1, 2020April 30, 2022CHEN, WEIQIANGreporter.nih.gov
Bacterial Rogue Methyltransferases Inducing Human EpimutationsNIHNational Cancer Institute2021 to 2022$91,888June 1, 2021August 31, 2022FINK, EMILY Ereporter.nih.gov
Ethics of the Choice of Invasive versus Non-invasive Neurosurgery: DifferentStakeholders' Perspectives, Surgical Decision-making, and Impact on Patient Sense ofControlNIHNational Institute of Mental Health2022$81,305July 21, 2020June 30, 2023KUBU, CYNTHIA M. S.reporter.nih.gov
Shared Mechanisms and Markers of Renal Injury and Neurocognitive Impairment in People with HIVNIHNational Institute of Mental Health2021$80,500August 1, 2020July 31, 2022KALLIANPUR, ASHA Rreporter.nih.gov
Development of motion correction algorithms for functional MRI data using a custom simultaneously excited multi-slice MRI acquisition with prospectively injected motionNIHNational Institute of Biomedical Imaging and Bioengineering2025$80,500February 1, 2025January 31, 2027SHIN, WANYONGreporter.nih.gov
Identifying imaging biomarkers of cognitive impairment in autoimmune encephalitisNIHNational Institute of Neurological Disorders and Stroke2025$80,500August 6, 2025July 31, 2027KUNCHOK, AMYreporter.nih.gov
A Hyper-Thrombotic State and Immunosuppression in GBMNIHNational Cancer Institute2024$75,928December 1, 2024November 30, 2027SLOAN, ANTHONY ROBERTreporter.nih.gov
Dissecting the roles of a novel immune-checkpoint receptor complex in driving T cell dysfunction in cancersNIHNational Cancer Institute2021 to 2022$75,699August 1, 2021May 18, 2023GILMOUR, CASSANDRAreporter.nih.gov
Human iPSC-derived Podocytes to Study APOL1 High-Risk VariantsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$74,936September 1, 2023August 31, 2025HAINES, LAUREN ELIZABETHreporter.nih.gov
Role of SerpinB3 in glioblastoma cancer stem cellsNIHNational Cancer Institute2021 to 2022$71,588January 1, 2021June 30, 2022LAUKO, ADAMreporter.nih.gov
C-Type Lectins and Immune Surveillance in ALDNIHNational Institute on Alcohol Abuse and Alcoholism2021$61,569September 1, 2021August 31, 2022KIM, ADAMreporter.nih.gov
Elucidating a novel metabolic mechanism of glucosamine-driven treatment resistance in castration-resistant prostate cancer through stimulation of 3b-HSD1-mediated DHEA metabolismNIHNational Cancer Institute2022$61,275June 1, 2022April 7, 2023VALLE, SHELLEYreporter.nih.gov
Clinical Scholars Career Development Program (CSCDP)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$60,000February 1, 2024January 31, 2027SPINDLER, KURT PAULreporter.nih.gov
Role of Hyperglycemia/Hyperinsulinemia in the Breakdown of the Blood Retinal Barrier in Diabetic RetinopathyNIHNational Eye Institute2024$48,974March 1, 2024February 28, 2027HERNANDEZ, KARENreporter.nih.gov
Optical monitoring of the role of neurogenesis in epileptogenesisNIHNational Institute of Neurological Disorders and Stroke2021$47,414March 5, 2021December 2, 2021ROGERS, MORGANreporter.nih.gov
Investigating the role of sulfide oxidation and declining hydrogen sulfide in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2025$43,138June 2, 2025May 31, 2028PONTI, ANDRAS KRISTOPHERreporter.nih.gov
SMARCA5 Inhibition as a Therapeutic Target for GlioblastomaNIHNational Cancer Institute2025$41,876December 1, 2025November 30, 2027GUTHRIE, MOLLYreporter.nih.gov
Research and Education towards Solutions for Late effects to Innovate, Excel, and Nurture after chronic Graft-versus-Host Disease (RESILIENT after cGVHD)NIHNational Heart, Lung, and Blood Institute2024$36,500January 1, 2024December 31, 2024ROTZ, SETH Jreporter.nih.gov
Clinician Scholar Career Development Program (CSCDP)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022$30,000July 1, 2019June 30, 2023SPINDLER, KURT PAULreporter.nih.gov
Role of the CX3CL1 C-terminus in reversing age-dependent Alzheimers neurodegenerationNIHNational Institute on Aging2022$28,267September 15, 2017April 30, 2018YAN, RIQIANGreporter.nih.gov
The 6th Annual International PTEN Symposium: From Patient-Centered Research to Clinical CareNIHNational Center for Advancing Translational Sciences2023$16,841March 20, 2023February 29, 2024ENG, CHARISreporter.nih.gov
4th Annual International PTEN Symposium: From Patient-Centered Research to Clinical CareNIHNational Center for Advancing Translational Sciences2021$5,000March 10, 2021March 9, 2022ENG, CHARISreporter.nih.gov

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025217$118,611,6570$0
2024226$121,208,3640$0
2023238$136,506,5950$0
2022241$125,295,9080$0
2021221$114,027,7830$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 3 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 2 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 59 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 59 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 59 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 59 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 59 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 59 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 59 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 59 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 59 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 59 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 59 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.853December 4, 2026Not listedSame assistance listing 93.853 as 59 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.853January 7, 2027$375,000Same assistance listing 93.853 as 59 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.853January 15, 2027$350,000Same assistance listing 93.853 as 59 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 59 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 59 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.853January 27, 2027$500,000Same assistance listing 93.853 as 59 awards here

Topics of its NIH awards

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.