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Data / Research funding / Massachusetts / Dana-Farber Cancer Inst

Dana-Farber Cancer Inst: 461 NIH awards ($821.3M) and 2 NSF awards ($202.7K), fiscal years 2021 to 2026

Dana-Farber Cancer Inst in Boston, MA is funded under 461 NIH awards ($821.3M) and 2 NSF awards ($202.7K) in the NIH and NSF award files, read 2026-11-03. NIH fiscal years 2021 to 2025; NSF fiscal years 2022 to 2026.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

UEI
DPMGH9MG1X67
State
Massachusetts

Awards

463 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
NCI Early Career Cancer Clinical Investigator AwardNIHNational Cancer Institute2021 to 2025$65,560,307March 10, 1997November 30, 2026EBERT, BENJAMIN LEVINEreporter.nih.gov
ECOG-ACRIN Network Group Statistics and Data Management CenterNIHNational Cancer Institute2021 to 2025$40,175,470April 29, 2014February 28, 2026GRAY, ROBERT Jreporter.nih.gov
Human Tumor Atlas Network: Data Coordinating CenterNIHNational Cancer Institute2023 to 2025$13,148,220September 30, 2018August 31, 2029GENTLEMAN, ROBERT Creporter.nih.gov
Biology and structure of pMHC receptors functioning as mechanosensors in the [alpha][beta] T-cell lineageNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,386,136July 29, 2020July 31, 2030REINHERZ, ELLIS Lreporter.nih.gov
Mechanisms and Therapy of Chronic Graft-vs.-Host DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$10,320,200September 15, 2022August 31, 2027CUTLER, COREY Sreporter.nih.gov
Development of Novel Therapeutic Strategies in Human LeukemiasNIHNational Cancer Institute2021 to 2025$9,780,487April 25, 1997August 31, 2030EBERT, BENJAMIN LEVINEreporter.nih.gov
Dana Farber/Harvard Cancer Center Specialized Program of Research Excellence in Breast CancerNIHNational Cancer Institute2021 to 2025$9,465,449September 17, 2013July 31, 2030POLYAK, KORNELIAreporter.nih.gov
Integrative Oncogenomics of Multiple MyelomaNIHNational Cancer Institute2021 to 2025$9,247,248December 1, 2011July 31, 2028MUNSHI, NIKHIL C.reporter.nih.gov
Dana Farber/Harvard Cancer Center SPORE in Lung CancerNIHNational Cancer Institute2022 to 2025$9,074,410August 1, 2022July 31, 2027BARBIE, DAVID Areporter.nih.gov
Dana Farber/Harvard Cancer Center Ovarian Cancer SPORE grantNIHNational Cancer Institute2021 to 2024$8,975,063August 3, 2020July 31, 2025D'ANDREA, ALAN D.reporter.nih.gov
2/2 The University of Massachusetts, Boston - Dana-Farber/Harvard Cancer Center U54 Comprehensive Partnership for Cancer Disparities ResearchNIHNational Cancer Institute2021 to 2025$8,436,106September 27, 2010August 31, 2026ABEL, GREGORY ALANreporter.nih.gov
Immune Modulation After Allogeneic HCTNIHNational Cancer Institute2021 to 2023$8,308,700August 14, 2019July 31, 2025SOIFFER, ROBERT JONreporter.nih.gov
Molecular phenotyping of ~100,000 coding variants across Mendelian disease genesNIHNational Human Genome Research Institute2021 to 2025$8,292,746August 23, 2021May 31, 2026VIDAL, MARCreporter.nih.gov
Comprehensive dissection of the CLL genome & phenome to improve patient outcomesNIHNational Cancer Institute2021 to 2025$8,043,507September 1, 2016August 31, 2026WU, CATHERINE JU-YINGreporter.nih.gov
DF/HCC Prostate SPORENIHNational Cancer Institute2023 to 2025$7,058,769September 1, 2023August 31, 2028BELTRAN, HIMISHAreporter.nih.gov
Dana-Farber/Harvard Cancer Center Experimental Therapeutics Clinical Trials Network Site (DF/HCC ETCTN Site)NIHNational Cancer Institute2021 to 2025$7,018,946March 13, 2014February 28, 2027SHAPIRO, GEOFFREY I.reporter.nih.gov
New therapeutic vulnerabilities in breast cancerNIHNational Cancer Institute2021 to 2024$6,857,044September 11, 2020May 31, 2026POLYAK, KORNELIAreporter.nih.gov
SPORE in Multiple MyelomaNIHNational Cancer Institute2021 to 2023$6,771,597September 16, 2003May 31, 2025ANDERSON, KENNETH C.reporter.nih.gov
Bioconductor: An Open-Source, Open-Development Computing Resource for GenomicsNIHNational Human Genome Research Institute2021 to 2025$6,327,693September 28, 2006February 28, 2027IRIZARRY, RAFAEL ANGELreporter.nih.gov
The Cellular Geography of Therapeutic Resistance in CancerNIHNational Cancer Institute2021 to 2023$6,163,685April 4, 2023August 31, 2024VAN ALLEN, ELIEZER Mreporter.nih.gov
Dana Farber/ Harvard Cancer Center SPORE in Gastrointestinal CancerNIHNational Cancer Institute2021 to 2023$5,953,561April 1, 2007May 31, 2025SELLERS, WILLIAM Rreporter.nih.gov
Targeting Replication Stress and DNA Damage Response in Uterine CancerNIHNational Cancer Institute2024 to 2025$5,927,036May 1, 2024April 30, 2029MATULONIS, URSULA ANNEreporter.nih.gov
Cancer Immune Monitoring and Analysis CenterNIHNational Cancer Institute2023 to 2025$5,746,876September 30, 2017June 30, 2028WU, CATHERINE JU-YINGreporter.nih.gov
Myeloma multidimensional precancer atlasNIHNational Cancer Institute2024 to 2025$5,566,942September 18, 2024August 31, 2029GHOBRIAL, IRENE M.reporter.nih.gov
NCTN Lead Academic Participating Site at Dana-Farber/Partners Cancer CareNIHNational Cancer Institute2021 to 2025$5,422,908March 5, 2019February 28, 2026BURSTEIN, HAROLD JOHNreporter.nih.gov
Targeting intratumor heterogeneity in breast cancerNIHNational Cancer Institute2021 to 2025$5,301,919August 1, 2015July 31, 2029POLYAK, KORNELIAreporter.nih.gov
Lung Adenocarcinoma: From Genome Alterations to Therapeutic DiscoveryNIHNational Cancer Institute2021 to 2025$5,246,301August 1, 2015July 31, 2028MEYERSON, MATTHEW L.reporter.nih.gov
Structure, mechanism, and pharmacology of BRAF and its partners in the RAS/RAF/MAP kinase pathwayNIHNational Cancer Institute2021 to 2025$5,243,880September 1, 2019August 31, 2026ECK, MICHAEL Jreporter.nih.gov
Dissecting and Targeting Deregulated Mitochondrial Apoptosis in Human CancerNIHNational Cancer Institute2021 to 2025$5,186,053August 24, 2015July 31, 2028WALENSKY, LOREN DAVIDreporter.nih.gov
Identification of Novel Oncogenic Signaling Pathways using Viral PerturbationsNIHNational Cancer Institute2021 to 2025$5,173,906August 8, 2019July 31, 2026DECAPRIO, JAMES A.reporter.nih.gov
Genomic and Genomic Variation in Prostate CancerNIHNational Cancer Institute2022 to 2025$5,164,514January 7, 2022April 30, 2027REBBECK, TIMOTHY RICHARDreporter.nih.gov
Reading mitochondrial apoptotic signaling to identify active cancer therapeuticsNIHNational Cancer Institute2021 to 2025$5,159,959August 1, 2019September 29, 2025LETAI, ANTHONY Greporter.nih.gov
Maximizing the Effectiveness of PI3K Inhibitors in the Treatment of Pten null CancersNIHNational Cancer Institute2021 to 2025$5,154,412September 1, 2019August 31, 2026ROBERTS, THOMAS Mreporter.nih.gov
Informed Combination Strategies for Peripheral T-cell LymphomasNIHNational Cancer Institute2021 to 2023$5,129,346September 1, 2019August 31, 2024KNOECHEL, BIRGITreporter.nih.gov
Radiation Oncology at the Interface of Pediatric Cancer Biology and Data ScienceNIHNational Cancer Institute2023 to 2025$5,032,714September 19, 2023August 31, 2028HAAS-KOGAN, DAPHNE A.reporter.nih.gov
Integrating targeted therapy and immunotherapy to break through cancerNIHNational Cancer Institute2021 to 2025$5,025,838September 1, 2016August 31, 2030ZHAO, JEANreporter.nih.gov
The von Hippel-Lindau Tumor Suppressor Gene and Kidney Cancer: Insights into Oxygen Sensing and Treating Cancers Caused by Undruggable MutationsNIHNational Cancer Institute2021 to 2025$4,888,860September 1, 2016August 31, 2030KAELIN, WILLIAM G.reporter.nih.gov
Identification of Metabolic and Immune Deficits in the Aged Population and Their Restoration to Achieve Youthful Anti-Influenza Vaccine ResponsivenessNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,757,817November 22, 2021October 31, 2026MARASCO, WAYNE A.reporter.nih.gov
RNA-based HIV-1 chimera vaccines encoding a trimerizing host self-protein protomer linked to a viral MPER-TM segmentNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$4,613,193April 1, 2024March 31, 2029REINHERZ, ELLIS Lreporter.nih.gov
Administrative supplement to Improving Advance Care Planning in Oncology: A Pragmatic, Cluster-Randomized Trial Integrating Patient Videosand Clinician Communication TrainingNIHNational Institute on Aging2021 to 2025$4,298,226July 1, 2018June 30, 2026TULSKY, JAMES A.reporter.nih.gov
Molecular Prediction of Myeloma Initiation Molecular Prediction of Myeloma InitiationNIHNational Cancer Institute2022 to 2025$4,108,272September 6, 2022August 31, 2029GHOBRIAL, IRENE M.reporter.nih.gov
Altered metabolism and machine learning for pancreatic cancer early detectionNIHNational Cancer Institute2021 to 2025$4,100,528September 16, 2022August 31, 2027WOLPIN, BRIAN MATTHEWreporter.nih.gov
Stromal modulation of pancreatic cancer malignant cell state and therapeutic sensitivityNIHNational Cancer Institute2022 to 2025$4,096,241September 19, 2022August 31, 2027HAHN, WILLIAM C.reporter.nih.gov
Development of Combination Therapies to Delay/Prevent Acquired Drug ResistanceNIHNational Cancer Institute2021 to 2024$4,095,825September 10, 2018August 31, 2025JANNE, PASI Areporter.nih.gov
The role of clonal hematopoiesis in the development and therapy of myeloid malignanciesNIHNational Cancer Institute2021 to 2024$3,926,618August 15, 2020November 1, 2024EBERT, BENJAMIN LEVINEreporter.nih.gov
Dissecting CCL5 contribution to antigen specific T cell responses in head and neck cancersNIHNational Institute of Dental & Craniofacial Research2025$3,742,682August 21, 2025August 20, 2029UPPALURI, RAVINDRAreporter.nih.gov
HIV-1 Preintegration Trafficking and Nuclear LocalizationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,586,576January 15, 2003May 31, 2027ENGELMAN, ALAN N.reporter.nih.gov
Biochemical Mechanism of HIV DNA IntegrationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,536,253June 1, 2025May 31, 2030ENGELMAN, ALAN N.reporter.nih.gov
Evolution of gliomas during treatment and resistanceNIHNational Cancer Institute2021 to 2025$3,464,231April 1, 2015June 30, 2026BEROUKHIM, RAMEENreporter.nih.gov
Molecular prediction of myeloma in African AmericansNIHNational Cancer Institute2022 to 2025$3,450,221September 12, 2022August 31, 2027MARINAC, CATHERINEreporter.nih.gov
Structure-activity relationships governing mammalian SWI/SNF chromatin remodeling activity as a function of chromatin stateNIHNational Cancer Institute2021 to 2025$3,409,205April 1, 2021March 31, 2026KADOCH, CIGALLreporter.nih.gov
Elucidation of the genetic mechanisms driving prostate tumorigenesis through integrative computational and functional approachesNIHNational Cancer Institute2021 to 2025$3,352,278March 2, 2021February 28, 2027FREEDMAN, MATTHEW Lreporter.nih.gov
Elucidating prostate cancer risk mechanisms through large-scale cistrome wide association studiesNIHNational Cancer Institute2022 to 2025$3,342,109September 1, 2022August 31, 2027FREEDMAN, MATTHEW Lreporter.nih.gov
A Stakeholder Informed Randomized Trial of Pretest Video Education vs Standard Genetic Counseling for Cancer Patients: Evaluating the Impact on Patients, Providers and PracticesNIHNational Human Genome Research Institute2021 to 2024$3,208,986September 22, 2021June 30, 2026RANA, HUMA Qreporter.nih.gov
Conformational Landscape of the HIV-1 Envelope GlycoproteinsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,207,950February 15, 2016March 31, 2027SODROSKI, JOSEPH Greporter.nih.gov
PGC1alpha Pathway: Novel Intracellular and Extracellular MediatorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,176,373February 1, 2019June 30, 2027SPIEGELMAN, BRUCE M.reporter.nih.gov
Targeting Pediatric Cancer VulnerabilitiesNIHNational Cancer Institute2023 to 2025$3,144,539September 19, 2023August 31, 2030STEGMAIER, KIMBERLYreporter.nih.gov
Genetic Predisposition to Chronic Lymphocytic Leukemia (CLL)NIHNational Cancer Institute2021 to 2025$3,143,480April 1, 2021March 31, 2027BROWN, JENNIFER Rreporter.nih.gov
PROTECT (Harnessing PROTEin degradation for Advanced Childhood Tumors)NIHNational Cancer Institute2024 to 2025$3,108,431May 1, 2024April 30, 2026STEGMAIER, KIMBERLYreporter.nih.gov
Role of Phosphoinositides and Protein Kinases in the control of Cancer MetabolismNIHNational Cancer Institute2022 to 2025$3,108,133September 5, 2016July 31, 2031CANTLEY, LEWIS C.reporter.nih.gov
Personal tumor neoantigens for immunity against chronic lymphocytic leukemiaNIHNational Cancer Institute2022 to 2025$2,996,021June 1, 2011January 31, 2027WU, CATHERINE JU-YINGreporter.nih.gov
Systematic identification of minor histocompatibility antigens to address GVHDNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,991,041April 1, 2022March 31, 2026KESKIN, DERIN Breporter.nih.gov
Molecular mechanisms underlying lineage plasticity in prostate cancerNIHNational Cancer Institute2021 to 2025$2,937,823April 1, 2025March 31, 2027BELTRAN, HIMISHAreporter.nih.gov
Tissue-based biomarkers of anti-PD-1-based therapy in metastatic renal cell carcinomaNIHNational Cancer Institute2022 to 2025$2,841,134July 1, 2022June 30, 2027CHOUEIRI, TONIreporter.nih.gov
Next Generation Computational Tools for Functional GenomicsNIHNational Human Genome Research Institute2021 to 2024$2,808,837September 22, 2020June 30, 2026IRIZARRY, RAFAEL ANGELreporter.nih.gov
Adapting and evaluating a brief advice tobacco intervention in high-reach, low-resource settings in IndiaNIHNational Cancer Institute2021 to 2024$2,800,655June 1, 2020May 31, 2026VISWANATH, KASISOMAYAJULAreporter.nih.gov
Defining mechanisms of extracellular succinate regulation over metabolic tissue functionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,748,905September 13, 2019June 30, 2028CHOUCHANI, EDWARD THOMASreporter.nih.gov
Development of microRNA (miR)-based cell-targeted polymeric nanoparticles for myeloma therapyNIHNational Cancer Institute2021 to 2025$2,723,368February 9, 2021March 31, 2027CARRASCO, RUBEN Dreporter.nih.gov
Generating a full-length reference transcriptome for human protein-coding genesNIHNational Human Genome Research Institute2022 to 2025$2,708,609August 22, 2022June 30, 2027VIDAL, MARCreporter.nih.gov
Probing the role of somatic X-chromosome alterations in shaping cancer sex differencesNIHNational Cancer Institute2023 to 2025$2,705,278September 20, 2023August 31, 2028VISWANATHAN, SRINIVAS RAGHAVANreporter.nih.gov
A precision tumor neoantigen identification pipeline for cytotoxic T-lymphocyte-based cancer immunotherapiesNIHNational Cancer Institute2022 to 2025$2,688,808March 1, 2022February 28, 2027REINHERZ, ELLIS Lreporter.nih.gov
Selective disruption of histone deacetylase complexes using protein interaction modulatorsNIHNational Cancer Institute2022 to 2025$2,674,355February 1, 2022January 31, 2027VIDAL, MARCreporter.nih.gov
How the 3D Architecture of the Brain Shapes Cancer Cell Fate DecisionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,670,000September 30, 2021August 31, 2026FILBIN, MARIELLA GRUBERreporter.nih.gov
Serologic and Molecular Studies of human anti-hCoV antibody cross-immunity and protective responses among endemic HCoVs and SARS-CoV2NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,655,001September 17, 2021August 31, 2025MARASCO, WAYNE A.reporter.nih.gov
Promoting Resilience in Early Survivorship among Adolescents and Young Adults with CancerNIHNational Cancer Institute2023 to 2025$2,642,459March 10, 2022February 28, 2027ROSENBERG, ABBY Rreporter.nih.gov
Synthetic lethalities to cell cycle disruption in gliomaNIHNational Cancer Institute2022 to 2025$2,642,252May 13, 2022April 30, 2027BEROUKHIM, RAMEENreporter.nih.gov
Probing functional HIV-1 envelope glycoprotein conformations with novel potent CD4-mimetic compoundsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,540,958July 10, 2023June 30, 2027SODROSKI, JOSEPH Greporter.nih.gov
Therapeutic Targeting of Immune Evasion from the MICA - NKG2D PathwayNIHNational Cancer Institute2021 to 2025$2,508,450March 1, 2019March 31, 2030WUCHERPFENNIG, KAI Wreporter.nih.gov
Discovery of cGAS-like signaling enzymes in innate immunity and diseaseNIHNational Institute of General Medical Sciences2021 to 2024$2,498,400September 24, 2021August 31, 2026KRANZUSCH, PHILIP Jreporter.nih.gov
Targeting SHP-1 through a newfound metabolite-regulated cysteine activation siteNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,496,633September 25, 2023July 31, 2028CHOUCHANI, EDWARD THOMASreporter.nih.gov
Leveraging Novel Randomized Clinical Trials of Vitamin D Supplementation in Patients with Colorectal Cancer: Impact on Survival and Anti-Tumor ImmunityNIHNational Cancer Institute2021 to 2025$2,477,583March 15, 2017June 30, 2027NG, KIMMIEreporter.nih.gov
Mouse models of Kras-mutant colorectal cancerNIHNational Cancer Institute2021 to 2024$2,463,211July 1, 2020June 30, 2026HAIGIS, KEVINreporter.nih.gov
Convergent Epigenetic Control of Neuroendocrine CancersNIHNational Cancer Institute2025$2,452,400April 1, 2025March 31, 2030DECAPRIO, JAMES A.reporter.nih.gov
Data Analysis Tools for Emerging High-throughput TechnologiesNIHNational Institute of General Medical Sciences2021 to 2025$2,410,347May 1, 2019May 31, 2030IRIZARRY, RAFAEL ANGELreporter.nih.gov
Discovery and optimization of novel mutant-selective allosteric inhibitors of EGFR T790MNIHNational Cancer Institute2021 to 2025$2,408,596December 1, 2015November 30, 2025ECK, MICHAEL Jreporter.nih.gov
Liquid biopsy approaches to inform osteosarcoma prognosis and tumor evolutionNIHNational Cancer Institute2021 to 2025$2,405,560July 1, 2025June 30, 2027CROMPTON, BRIANreporter.nih.gov
The construction and utility of reference pan-genome graphsNIHNational Human Genome Research Institute2021 to 2023$2,401,989February 4, 2023February 29, 2024LI, HENGreporter.nih.gov
Translation of a Bismuth-Gadolinium Nanoparticle for MR-guided Radiation TherapyNIHNational Cancer Institute2021 to 2024$2,352,523March 1, 2020February 28, 2026BERBECO, ROSS I.reporter.nih.gov
Physician Scientist Training in Cancer ResearchNIHNational Cancer Institute2021 to 2025$2,326,588July 1, 1978June 30, 2027DECAPRIO, JAMES A.reporter.nih.gov
A novel flat-panel detector for advanced on-board radiation therapy imagingNIHNational Cancer Institute2021 to 2024$2,324,892September 1, 2014June 30, 2025BERBECO, ROSS I.reporter.nih.gov
Axonal transport and chemotherapy induced peripheral neuropathyNIHNational Cancer Institute2022 to 2025$2,319,802April 1, 2016June 30, 2027SEGAL, ROSALIND A.reporter.nih.gov
Immunotherapeutic targeting of gangliosides in Ewing SarcomaNIHNational Cancer Institute2023 to 2025$2,317,710September 19, 2023August 31, 2028MAJZNER, ROBBIE G.reporter.nih.gov
Defining the landscape and mechanisms of protein redox regulation during agingNIHNational Institute on Aging2022 to 2025$2,304,037September 15, 2022June 30, 2027CHOUCHANI, EDWARD THOMASreporter.nih.gov
Tracing the lineage histories and differentiation trajectories of individual cancer cells in myeloproliferative neoplasmsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,295,485January 15, 2021January 31, 2026HORMOZ, SAHANDreporter.nih.gov
Mechanisms of eIF3-mediated translation regulationNIHNational Institute of General Medical Sciences2021 to 2025$2,238,573August 16, 2021July 31, 2026LEE, AMY SI-YINGreporter.nih.gov
CDK4/6 inhibition during CD8 T cell priming potentiates memory formation in mice and humansNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,225,000April 5, 2021March 31, 2027DOUGAN, STEPHANIEreporter.nih.gov
Consequences of retrotransposition on genome integrityNIHNational Cancer Institute2023 to 2025$2,208,749August 1, 2023July 31, 2028BURNS, KATHLEEN Hreporter.nih.gov
Molecular Pathogenesis of Fanconi AnemiaNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,183,099August 1, 1994December 31, 2027D'ANDREA, ALAN D.reporter.nih.gov
Mitoribosome protein translation signaling and survival mechanismsNIHNational Institute on Aging2023 to 2025$2,167,472September 30, 2023May 31, 2028PUIGSERVER, PEREreporter.nih.gov
SPORE in Myeloid MalignanciesNIHNational Cancer Institute2021$2,138,999September 19, 2017July 31, 2023EBERT, BENJAMIN LEVINEreporter.nih.gov
Targeting Nucleotide Excision Repair Deficiency to Improve Bladder Sparing Treatment for Muscle Invasive Bladder CancerNIHNational Cancer Institute2022 to 2025$2,132,323September 22, 2022August 31, 2027MOUW, KENT Wreporter.nih.gov
Mechanisms of Toxicity Induced by EWS/FLI1 Overdose in Ewing SarcomaNIHNational Cancer Institute2023 to 2025$2,124,600June 7, 2023May 31, 2028STEGMAIER, KIMBERLYreporter.nih.gov
Developing Informatics Technologies to Model Cancer Gene RegulationNIHNational Cancer Institute2021 to 2023$2,108,794March 15, 2019February 29, 2024MEYER, CLIFFORDreporter.nih.gov
BOLSTER: Strengthening Patient and Caregiver Supports in Advanced Gynecologic and Gastrointestinal Cancers - a Multi-Site Randomized Controlled TrialNIHNational Cancer Institute2023 to 2025$2,088,479February 1, 2023July 31, 2028WRIGHT, ALEXI Areporter.nih.gov
Development and vascularity of intestinal mesenchymeNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,083,022June 1, 2019April 30, 2028SHIVDASANI, RAMESH Areporter.nih.gov
Mechanisms and Vulnerabilities of Aberrant Transcriptional Enhancers in CancerNIHNational Cancer Institute2021 to 2022$2,071,954September 1, 2016August 31, 2023LOOK, A. THOMASreporter.nih.gov
Integrating Transforming Approaches to Identify and Target New Vulnerabilities in CancerNIHNational Cancer Institute2021 to 2022$2,071,953August 9, 2016July 31, 2023STEGMAIER, KIMBERLYreporter.nih.gov
Cyclin C-CDK8/19 kinases in development and in cancerNIHNational Cancer Institute2022 to 2025$2,067,060March 1, 2022February 28, 2027SICINSKI, PETERreporter.nih.gov
Advanced computational methods in analyzing high-throughput sequencing dataNIHNational Human Genome Research Institute2021 to 2025$2,058,625May 1, 2018February 28, 2027LI, HENGreporter.nih.gov
Regulatory mechanisms of mitochondrial cristae biogenesis and thermogenic functionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,047,746August 1, 2023July 31, 2027PUIGSERVER, PEREreporter.nih.gov
Developing non-immunosuppressive immune-based therapeutics for targeted treatment of autoimmune diseasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,028,057August 24, 2023July 31, 2028RASHIDIAN, MOHAMMADreporter.nih.gov
Mechanisms Driving the Rapid Evolution of Cancer GenomesNIHNational Cancer Institute2024 to 2025$2,010,442September 1, 2024August 31, 2031PELLMAN, DAVID Sreporter.nih.gov
Optimizing Therapeutic STING Agonism in Triple Negative Breast CancerNIHNational Cancer Institute2021 to 2025$2,007,374April 1, 2021March 31, 2027BARBIE, THANH UYENreporter.nih.gov
Molecular origins and evolution to chemoresistance in germ cell tumorsNIHNational Cancer Institute2021 to 2024$2,002,931February 1, 2023January 31, 2025VAN ALLEN, ELIEZER Mreporter.nih.gov
Targeting vulnerabilities of PPM1D-mutant gliomasNIHNational Cancer Institute2021 to 2025$1,989,782February 1, 2021January 31, 2026BANDOPADHAYAY, PRATITIreporter.nih.gov
Defining epigenetic mechanisms in NPM1c mutant leukemiaNIHNational Cancer Institute2021 to 2025$1,981,710April 9, 2021March 31, 2027ARMSTRONG, SCOTT Areporter.nih.gov
Novobiocin-mediated polymerase theta inhibition in homologous recombination repair-deficient cancersNIHNational Cancer Institute2022 to 2025$1,976,994September 1, 2022August 31, 2027SHAPIRO, GEOFFREY I.reporter.nih.gov
The molecular basis of IMiD induced neo-substrate recruitment to the CRL4CRBN ubiquitin E3 ligaseNIHNational Cancer Institute2021 to 2025$1,973,693March 1, 2017March 31, 2027FISCHER, ERIC SEBASTIANreporter.nih.gov
Bioethics research to understand engagement in decision-making among adolescents and young adults with cancer at risk for health care disparitiesNIHNational Cancer Institute2023 to 2025$1,967,607September 1, 2025August 31, 2026MACK, JENNIFER Wreporter.nih.gov
Training in Oncology Population Sciences (TOPS)NIHNational Cancer Institute2021 to 2025$1,967,226September 1, 2002August 31, 2029MACK, JENNIFER Wreporter.nih.gov
Small molecules targeting hepatic glucose production and insulin resistanceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,962,658March 21, 2019February 28, 2025PUIGSERVER, PEREreporter.nih.gov
End-of-life care quality for adolescents and young adults with cancer: Including the patient voice in quality assessmentNIHNational Cancer Institute2021 to 2025$1,960,563February 13, 2018December 31, 2029MACK, JENNIFER Wreporter.nih.gov
Polyploidy, Aneuploidy and Genome StabilityNIHNational Cancer Institute2021 to 2024$1,959,860May 30, 1997November 30, 2024PELLMAN, DAVID Sreporter.nih.gov
Development and implementation of multiplex methods to understand the biology and heterogeneity of patient-derived cancer modelsNIHNational Cancer Institute2021 to 2022$1,926,843June 15, 2020May 31, 2023HAHN, WILLIAM C.reporter.nih.gov
NMR Fingerprinting: Leveraging optimal control pulse design, tailored isotope labeling, and machine learning to study intractable proteinsNIHNational Institute of General Medical Sciences2021 to 2024$1,905,230June 1, 2020March 31, 2025ARTHANARI, HARIBABUreporter.nih.gov
Targeting of a Major Immune Evasion Pathway in Triple-negative Breast CancerNIHNational Cancer Institute2021 to 2024$1,897,891August 1, 2020April 30, 2026WUCHERPFENNIG, KAI Wreporter.nih.gov
Dissecting neoepitope-specific clonal T cell populations in advanced melanoma patients vaccinated with personal neoantigen peptides partnered with local and systemic immune checkpoint InhibitionNIHNational Cancer Institute2021 to 2023$1,871,288September 6, 2018August 31, 2025OTT, PATRICK ALEXANDERreporter.nih.gov
Research Training in Pediatric OncologyNIHNational Cancer Institute2021 to 2024$1,864,901July 13, 2009June 30, 2025ARMSTRONG, SCOTT Areporter.nih.gov
Protein Kinase Therapeutic Targets for Non-Small Cell Lung CarcinomaNIHNational Cancer Institute2021$1,846,173May 11, 2012August 31, 2023MEYERSON, MATTHEW L.reporter.nih.gov
Taking AIM at Breast Cancer: Targeting Adiposity and Inflammation with Movement to Improve Prognosis in Breast Cancer SurvivorsNIHNational Cancer Institute2021 to 2023$1,845,213September 1, 2018August 31, 2025DIELI-CONWRIGHT, CHRISTINAreporter.nih.gov
Development of a generalizable chemo-proteomics screening platform for small molecule degraders applied to HDACsNIHNational Cancer Institute2022 to 2025$1,822,992June 7, 2022April 30, 2026FISCHER, ERIC SEBASTIANreporter.nih.gov
CDC7 kinase in normal and cancer cells: potential implications for cancer treatmentNIHNational Cancer Institute2021 to 2024$1,822,777December 1, 2019November 30, 2024SICINSKI, PETERreporter.nih.gov
Statistical methods for cancer mutational signaturesNIHNational Cancer Institute2021 to 2025$1,815,915July 1, 2021June 30, 2026PARMIGIANI, GIOVANNI LUIGIreporter.nih.gov
Engineering dendritic cells to target islet antigen to pro-tolerogenic subsets for prevention and treatment of Type 1 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,780,000April 1, 2022March 31, 2027AGUDO CANTERO, JUDITHreporter.nih.gov
Individualizing Approaches to Surveillance Mammography in Older Breast Cancer SurvivorsNIHNational Institute on Aging2024 to 2025$1,777,442September 15, 2024August 31, 2030FREEDMAN, RACHEL ANNreporter.nih.gov
Dissecting the interaction between DNA damage repair defects and the tumor microenvironmentNIHOffice of the Director, National Institutes of Health2021 to 2024$1,770,000September 16, 2020August 31, 2025HILL, SARAH JAMESreporter.nih.gov
Targeting blastic plasmacytoid dendritic cell neoplasm (BPDCN)NIHNational Cancer Institute2021 to 2024$1,737,621February 1, 2018January 31, 2026LANE, ANDREW Areporter.nih.gov
Rewiring of regulatory networks in breast cancer by transcription factor isoformsNIHNational Cancer Institute2021 to 2022$1,735,449September 17, 2018February 29, 2024VIDAL, MARCreporter.nih.gov
Enhancement and further development of informatics methods for long-read cancer sequencingNIHNational Cancer Institute2024 to 2025$1,730,589September 1, 2024August 31, 2029LI, HENGreporter.nih.gov
Targeting the MUC1-C Oncoprotein in Triple-Negative Breast CancerNIHNational Cancer Institute2021 to 2025$1,714,463July 1, 2002March 31, 2029KUFE, DONALD W.reporter.nih.gov
Investigating and modeling MYD88L265P and co-occurring mutations in mature B-cell malignanciesNIHNational Cancer Institute2022 to 2025$1,713,034August 1, 2022July 31, 2027CARRASCO, RUBEN Dreporter.nih.gov
Early change in plasma tumor DNA as a patient and trial-level diagnostic in advanced lung cancerNIHNational Cancer Institute2021 to 2024$1,712,649February 15, 2020January 31, 2025PAWELETZ, CLOUD PETERreporter.nih.gov
Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) TrialNIHNational Cancer Institute2023 to 2025$1,709,232April 1, 2021September 30, 2026BAO, TINGreporter.nih.gov
NexTGen - DFCINIHNational Cancer Institute2023 to 2025$1,705,825June 1, 2025May 31, 2026MAJZNER, ROBBIE G.reporter.nih.gov
Molecular and immune drivers of immunotherapy responsiveness in prostate cancerNIHNational Cancer Institute2021 to 2022$1,689,999September 19, 2018August 31, 2023VAN ALLEN, ELIEZER Mreporter.nih.gov
Hijacking the T cell machinery for logic-gated CAR T cell controlNIHNational Cancer Institute2021 to 2024$1,684,559September 24, 2021August 31, 2026MAJZNER, ROBBIE G.reporter.nih.gov
Stapled Peptides for Protein Interaction Research and Therapeutic Targeting in Human CancerNIHNational Cancer Institute2021 to 2025$1,660,410September 15, 2016August 31, 2026BIRD, GREGORY HOWARDreporter.nih.gov
MUC1-C is a Target for Reversing Immune Evasion and Resistance to ImmunotherapiesNIHNational Cancer Institute2021 to 2022$1,659,300September 20, 2018August 31, 2024KUFE, DONALD W.reporter.nih.gov
Mechanisms of response and resistance to KRAS inhibition in pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,657,228January 1, 2023December 31, 2027AGUIRRE, ANDREW JAMESreporter.nih.gov
High-throughput single-cell RNA sequencing of bacteria to uncover cell states involved in pathogenesisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,646,044June 20, 2024April 30, 2029HORMOZ, SAHANDreporter.nih.gov
Identification of Novel Protein Kinases Dependent on Phosphocreatine Rather than ATPNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,641,114August 31, 2018July 31, 2024SPIEGELMAN, BRUCE M.reporter.nih.gov
Enhanced radiotherapy for pediatric glioma via synthetic lethal vulnerabilitiesNIHNational Cancer Institute2024 to 2025$1,637,935July 1, 2024June 30, 2026CHOWDHURY, DIPANJANreporter.nih.gov
Targeting the cytokine circuitry of KRAS-driven lung cancerNIHNational Cancer Institute2021 to 2024$1,625,555April 1, 2015May 31, 2026BARBIE, DAVID Areporter.nih.gov
Human Cancer Suppressor Functions of Protein Phosphatase 2ANIHNational Cancer Institute2021$1,613,905August 1, 2017July 31, 2023DECAPRIO, JAMES A.reporter.nih.gov
A web-based patient-reported symptom monitoring and self-management portal for adolescent and young adult breast cancer survivorsNIHNational Cancer Institute2023 to 2024$1,613,871September 18, 2020August 31, 2025PARTRIDGE, ANN Hreporter.nih.gov
Optimizing novel agent combination therapy for previously untreated, high risk chronic lymphocytic leukemiaNIHNational Cancer Institute2022 to 2025$1,603,351September 15, 2022June 30, 2027DAVIDS, MATTHEW Sreporter.nih.gov
Engineering programmable enzymes for proteome editingNIHNational Institute of General Medical Sciences2023$1,602,000September 1, 2023August 31, 2026ZHOU, XINreporter.nih.gov
Computational methods for multiplex image analysis of the tumor microenvironmentNIHNational Library of Medicine2025$1,602,000September 1, 2025August 31, 2029LOTTER, WILLIAM EDWARDreporter.nih.gov
Cellular and Biochemical Pathways of Adipose Metabolism and ThermogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,596,762December 10, 2019November 30, 2024SPIEGELMAN, BRUCE M.reporter.nih.gov
Cell lineage as an indicator of immune response in neuroblastomaNIHNational Cancer Institute2022 to 2025$1,593,136June 16, 2022May 31, 2027GEORGE, RANI E.reporter.nih.gov
Characterizing the LINE-1 Retrotransposition-Replication ConflictNIHNational Cancer Institute2021 to 2024$1,583,112July 15, 2020June 30, 2025BURNS, KATHLEEN Hreporter.nih.gov
Metabolic and epigenetic dependencies in melanomas during metastasis and targeted-drug resistanceNIHNational Cancer Institute2021 to 2024$1,582,220July 1, 2014March 31, 2026PUIGSERVER, PEREreporter.nih.gov
Targeting of tumor cell DHHC3 to enhance anti-cancer immunityNIHNational Cancer Institute2021 to 2024$1,564,826March 1, 2020February 28, 2025HEMLER, MARTIN Ereporter.nih.gov
Analysis of ECOG-ACRIN adverse event data to optimize strategies for the longitudinal assessment of tolerability in the context of evolving cancer treatment paradigms (EVOLV)NIHNational Cancer Institute2021 to 2023$1,553,684July 10, 2023August 31, 2024GRAY, ROBERT Jreporter.nih.gov
Elucidating the molecular mechanism and physiological relevance of TIRR mediated inhibition of p53NIHNational Cancer Institute2022 to 2025$1,529,566July 1, 2022June 30, 2027CHOWDHURY, DIPANJANreporter.nih.gov
Statistical Methods and Validation Analyses for the Integration of External Data in Clinical TrialsNIHNational Library of Medicine2021 to 2024$1,524,272April 7, 2021December 31, 2025TRIPPA, LORENZOreporter.nih.gov
Molecular mechanisms and therapeutic targeting of activated NRF2 signaling in MiT/TFE translocation renal cell carcinomaNIHNational Cancer Institute2023 to 2025$1,516,110August 1, 2023July 31, 2028VISWANATHAN, SRINIVAS RAGHAVANreporter.nih.gov
Variability in Opioid Prescribing Across the Cancer Care Continuum: A Multi-Level AnalysisNIHNational Cancer Institute2024 to 2025$1,501,571February 21, 2024January 31, 2029ENZINGER, ANDREA Creporter.nih.gov
Metabolic crosstalks in regulation of beta-cell stress response and adaptationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,469,732February 1, 2008March 31, 2027DANIAL, NIKA Nreporter.nih.gov
Dissecting Integrated Cellular Programs Promoting Platinum Resistance and Progression in Bladder CancerNIHNational Cancer Institute2024 to 2025$1,461,918April 1, 2024March 31, 2029VAN ALLEN, ELIEZER Mreporter.nih.gov
Design of a Scalable and Sustainable PREMMplus Patient-Facing App and Implementation in Three Healthcare SettingsNIHNational Cancer Institute2024 to 2025$1,455,977September 4, 2024August 31, 2029SYNGAL, SAPNAreporter.nih.gov
The role of NCOA4-mediated ferritinophagy in iron homeostasis and ferroptosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,455,601April 1, 2020March 31, 2026MANCIAS, JOSEPH Dreporter.nih.gov
Novel Health Equity Intervention to Improve Pediatric Oncology Outcome Disparities: Targeting Poverty and Psychosocial StressNIHNational Cancer Institute2022 to 2023$1,449,123March 1, 2022February 29, 2028BONA, KIRA O.reporter.nih.gov
Transcriptional control and enhancer recruitment in mouse and human intestinal secretory differentiationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,447,944September 1, 2010February 29, 2028SHIVDASANI, RAMESH Areporter.nih.gov
Merkel cell polyomavirus HLA class I epitopes for generating therapeutic T cell-based cancer immunotherapyNIHNational Cancer Institute2024 to 2025$1,438,870January 9, 2024December 31, 2028KESKIN, DERIN Breporter.nih.gov
Randomized trial of REVITALIZE: A telehealth intervention to reduce fatigue interference among adults with advanced ovarian cancer on PARP inhibitorsNIHNational Cancer Institute2024 to 2025$1,433,938June 1, 2024May 31, 2029WRIGHT, ALEXI Areporter.nih.gov
Mechanism and functional consequences of dietary lipids in lineage specification and tumor growth in oncohistone gliomasNIHNational Cancer Institute2024 to 2025$1,424,418April 1, 2024March 31, 2029DANIAL, NIKA Nreporter.nih.gov
Dissecting Convergent Somatic and Germline Alterations that Mediate the Origins and Evolution of Kidney CancerNIHNational Cancer Institute2024 to 2025$1,419,944January 1, 2024December 31, 2028VAN ALLEN, ELIEZER Mreporter.nih.gov
Novel therapeutic approaches with CDK4/6 inhibitors for melanoma treatmentNIHNational Cancer Institute2021 to 2023$1,413,825December 1, 2018November 30, 2024SICINSKI, PETERreporter.nih.gov
(PQ3) A functional genomic approach to identification and interpretation of germline-tumor genetic interactionsNIHNational Cancer Institute2021 to 2022$1,400,066June 8, 2018May 31, 2024GUSEV, ALEXANDERreporter.nih.gov
BIDIRECTIONAL TRAINING TO ENHANCE CANCER RESEARCH CAPACITY IN AFRICANIHNational Cancer Institute2021 to 2025$1,388,758May 5, 2021April 30, 2027REBBECK, TIMOTHY RICHARDreporter.nih.gov
HEME-Hospice: An Intervention to improve Hospice Use for Patients with Hematologic MalignanciesNIHNational Cancer Institute2024 to 2025$1,375,196June 1, 2024May 31, 2029MACK, JENNIFER Wreporter.nih.gov
Tissue-specific genetic interactions in cancerNIHNational Cancer Institute2021 to 2022$1,375,018June 20, 2018May 31, 2024HAIGIS, KEVINreporter.nih.gov
Mechanisms by which LSD1 Promotes Neuroendocrine Differentiation and Small Cell Lung CancerNIHNational Cancer Institute2023 to 2025$1,367,119December 6, 2022November 30, 2027OSER, MATTHEW GILBERTreporter.nih.gov
Assessment of germline variants associated with immune-related adverse events following immune checkpoint inhibitorsNIHNational Cancer Institute2024 to 2025$1,357,987September 17, 2024August 31, 2029CHOUEIRI, TONIreporter.nih.gov
Mechanisms of immune evasion in T-cell acute lymphoblastic leukemia and its therapeutic implicationsNIHNational Cancer Institute2021 to 2024$1,355,619August 24, 2021August 31, 2024KNOECHEL, BIRGITreporter.nih.gov
Interface-resolution domain-domain interactome map of the yeast complexomeNIHNational Institute of General Medical Sciences2021 to 2022$1,340,062April 20, 2019February 29, 2024VIDAL, MARCreporter.nih.gov
Molecular origins and evolution to treatment resistance in genitourinary cancersNIHNational Cancer Institute2022 to 2025$1,321,652August 1, 2022July 31, 2027PARK, JIHYEreporter.nih.gov
The Function of CDK5 in MetastasisNIHNational Cancer Institute2021 to 2023$1,306,325March 1, 2019February 28, 2025SICINSKI, PETERreporter.nih.gov
Scaling up tobacco control in India: Comparing smartphone to in-person training for implementing an evidence-based intervention to reduce tobacco use among schoolteachersNIHNational Cancer Institute2021 to 2024$1,305,092September 1, 2021July 31, 2025NAGLER, EVE Mreporter.nih.gov
Effects of marijuana use on inflammation and vascular injury in adults with HIV infectionNIHNational Institute on Drug Abuse2021 to 2022$1,297,182April 1, 2018February 28, 2025GABUZDA, DANA H.reporter.nih.gov
Acupuncture for Chemothrapy-induced Peripheral Neuropathy Treatment (ACT) TrialNIHNational Cancer Institute2024 to 2025$1,263,296December 1, 2023November 30, 2025BAO, TINGreporter.nih.gov
Anatomic and functional characterization of the intestinal crypt-villus nicheNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,258,950September 1, 2014August 31, 2024SHIVDASANI, RAMESH Areporter.nih.gov
Can a subset of patients with HER2+ metastatic breast cancer be cured?NIHNational Cancer Institute2021 to 2025$1,229,054April 1, 2021July 1, 2025PARSONS, HEATHER ANNEreporter.nih.gov
Cancer-Specific Targeting and Function of Mammalian SWI/SNF (BAF) Chromatin Remodeling ComplexesNIHNational Cancer Institute2021 to 2023$1,227,497March 21, 2019February 29, 2024KADOCH, CIGALLreporter.nih.gov
Regulators of Cancer Immunotherapy ResponseNIHNational Cancer Institute2021 to 2022$1,203,365May 15, 2019April 30, 2024BROWN, MYLES Areporter.nih.gov
Novel Screening Platform for Discovery of DUB Targeting ProbesNIHNational Cancer Institute2021 to 2022$1,202,534June 1, 2019May 31, 2024BUHRLAGE, SARA Jreporter.nih.gov
Mechanisms of natural killer cell resistance of treatment-persistent residual tumor cells in hematologic malignanciesNIHNational Cancer Institute2023 to 2025$1,194,750January 1, 2023December 31, 2027MITSIADES, CONSTANTINE S.reporter.nih.gov
Incomplete Penetrance via Edgetic SuppressionNIHNational Institute of General Medical Sciences2021 to 2022$1,182,382September 10, 2019August 31, 2024VIDAL, MARCreporter.nih.gov
Cancer Chemical Biology and Metabolism Training ProgramNIHNational Cancer Institute2021 to 2023$1,167,548April 1, 2019March 31, 2025DANIAL, NIKA Nreporter.nih.gov
Regulation and targeting of tumor cell states and plasticity in pancreatic cancerNIHNational Cancer Institute2022 to 2025$1,164,735September 1, 2022August 31, 2027RAGHAVAN, SRIVATSANreporter.nih.gov
Immunotherapeutic responses to neoantigens in head and neck cancerNIHNational Institute of Dental & Craniofacial Research2021 to 2022$1,150,293April 11, 2018March 31, 2024UPPALURI, RAVINDRAreporter.nih.gov
BMT CTN Core - Dana-Farber Cancer Institute and MGH ConsortiumNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,133,713September 30, 2001June 30, 2031GOOPTU, MAHASWETAreporter.nih.gov
CDK7 inhibitors as a new strategy to overcome treatment resistance in ER+ metastatic breast cancerNIHNational Cancer Institute2021 to 2023$1,125,683August 16, 2019July 31, 2025JESELSOHN, RINATH M.reporter.nih.gov
(PQ5) Contribution of mitochondrial pathways to metabolic heterogeneity in molecular subtypes of Diffuse Large B Cell LymphomaNIHNational Cancer Institute2021 to 2022$1,104,883September 1, 2018February 29, 2024DANIAL, NIKA Nreporter.nih.gov
Molecular mechanisms of developmental reprogramming in colorectal cancerNIHNational Cancer Institute2024 to 2025$1,103,696September 1, 2024August 31, 2029SETHI, NILAYreporter.nih.gov
Comprehensive genomic profiling of aggressive hormone sensitive prostate cancerNIHNational Cancer Institute2021 to 2022$1,091,437May 1, 2020April 30, 2023SWEENEY, CHRISTOPHER Jreporter.nih.gov
Novel targeted therapies for chronic myelomonocytic leukemiaNIHNational Cancer Institute2022 to 2025$1,076,976September 2, 2022August 31, 2027BELIZAIRE, ROGER VINCENTreporter.nih.gov
Regulation of androgen receptor signaling in prostate cancer by protein arginine methylationNIHNational Cancer Institute2023 to 2024$1,076,279April 1, 2023March 31, 2028VISWANATHAN, SRINIVAS RAGHAVANreporter.nih.gov
Assay Validation of a Circulating miRNA Test for Diagnosis and Monitoring of Malignant Germ Cell TumorsNIHNational Cancer Institute2022 to 2024$1,075,002September 2, 2019April 30, 2025FRAZIER, ANNE LINDSAYreporter.nih.gov
EZH2 in cancer biology and novel inhibitorsNIHNational Cancer Institute2021 to 2022$1,065,357August 1, 2018July 31, 2023QI, JUNreporter.nih.gov
Deciphering the mechanism underlying BRCA1 breast cancer developmentNIHNational Cancer Institute2021$1,053,423August 7, 2019February 28, 2023LIVINGSTON, DAVID MORSEreporter.nih.gov
Cell Cycle Control of the CytoskeletonNIHNational Institute of General Medical Sciences2021 to 2023$1,041,300July 1, 2000July 31, 2024PELLMAN, DAVID Sreporter.nih.gov
High-Throughput DNA Sequencing SystemNIHOffice of the Director, National Institutes of Health2024$1,035,125July 15, 2024June 30, 2025HERBERT, ZACHARY Treporter.nih.gov
Enhancing Venetoclax Activity in Chemoresistant Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2024$1,034,244March 1, 2020August 31, 2025GARCIA, JACQUELINE SUENreporter.nih.gov
Harnessing naturally occurring cell type-specific regulatory elements and normal HSC hematopoiesis to develop cell lineage-controlled CAR expression and continuously renewing CAR NK cellsNIHNational Cancer Institute2024 to 2025$1,027,718August 1, 2024July 31, 2029SMITH, ERIC Lreporter.nih.gov
Targeting High-Risk Lymphoid NeoplasmsNIHNational Cancer Institute2021$1,021,025August 1, 2019June 30, 2022WEINSTOCK, DAVID MARCreporter.nih.gov
Diversifying Acute Leukemia Clinical Trial Enrollment Through Multilevel InterventionNIHNational Cancer Institute2022 to 2025$1,020,592July 1, 2022June 30, 2027HANTEL, ANDREWreporter.nih.gov
Integrative modelling of single-cell data to elucidate the genetic architecture of complex diseaseNIHNational Human Genome Research Institute2024 to 2025$1,009,988August 1, 2024April 30, 2028GUSEV, ALEXANDERreporter.nih.gov
The Dana-Farber Cancer Institute Cancer Target Discovery and Development CenterNIHNational Cancer Institute2021$1,007,904May 1, 2013July 31, 2023HAHN, WILLIAM C.reporter.nih.gov
Contribution of a novel OPN-producing CD11c+ microglial subset to ADNIHNational Institute on Aging2024 to 2025$1,001,829February 1, 2024December 31, 2028CANTOR, HARVEYreporter.nih.gov
Cancer Immunologic Data Commons (CIDC) Supplement RequestNIHNational Cancer Institute2022$1,000,000September 30, 2017June 30, 2023CERAMI, ETHANreporter.nih.gov
Dissecting and Targeting MAPK - PPARG Crosstalk in Bladder CancerNIHNational Cancer Institute2024 to 2025$985,050May 1, 2024April 30, 2029MOUW, KENT Wreporter.nih.gov
Postdoctoral Training Program in AIDS-related ResearchNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$978,766August 1, 1990May 31, 2025CANTOR, HARVEYreporter.nih.gov
Tumor and host markers of clinical outcomes after MIBG therapy in neuroblastomaNIHNational Cancer Institute2021 to 2023$942,428April 15, 2018March 31, 2025DUBOIS, STEVENreporter.nih.gov
Biomarker screening algorithms for the improved early detection of hepatocellular carcinomaNIHNational Cancer Institute2021 to 2025$921,328April 1, 2019March 31, 2027TAYOB, NABIHAHreporter.nih.gov
Investigating Transcriptional Elongation and Nuclear RNA Surveillance in MelanomaNIHNational Cancer Institute2021 to 2025$919,990April 1, 2021March 31, 2027INSCO, MEGAN LEIGHreporter.nih.gov
Comprehensive minimal residual disease tracking in cancerNIHNational Cancer Institute2024 to 2025$908,380June 1, 2018November 30, 2026MAKRIGIORGOS, G. MIKEreporter.nih.gov
Single cell investigation of co-evolution in cancer cells and host cell immune microenvironmentNIHNational Cancer Institute2021 to 2025$906,086August 15, 2020July 31, 2030LI, SHUQIANGreporter.nih.gov
Development and validation of clinical prediction models for the use and interpretation of multigene hereditary cancer risk assessmentNIHNational Cancer Institute2021 to 2022$901,778September 30, 2008January 31, 2025SYNGAL, SAPNAreporter.nih.gov
Genetic dissection of visceral pain pathwaysNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$890,366July 1, 2019September 16, 2022MA, QIUFUreporter.nih.gov
Approaches to inducing broadly neutralizing antibodies with immunogens mimicking steric occlusion of the MPER as configured on the HIV-1virion surfaceNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$890,000August 1, 2019July 31, 2024KIM, MIKYUNGreporter.nih.gov
Molecular mechanisms of splicing dependency in cohesin-mutant myelodysplasiaNIHNational Heart, Lung, and Blood Institute2024 to 2025$890,000December 1, 2023November 30, 2028TOTHOVA, ZUZANAreporter.nih.gov
Elucidating the impact of DNA hypomethylation on genome organization and anti-tumor transcriptional programsNIHNational Cancer Institute2021 to 2025$888,619April 1, 2021March 31, 2027JOHNSTONE, SARAH Ereporter.nih.gov
Defining LncRNA Function in normal and Shwachman Diamond Syndrome MyelopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2022$882,500January 15, 2019December 31, 2023NOVINA, CARL Dreporter.nih.gov
Functional Genomic Dissection of Refractory AnemiaNIHNational Heart, Lung, and Blood Institute2021 to 2022$882,500September 15, 2005May 31, 2024EBERT, BENJAMIN LEVINEreporter.nih.gov
NMR-based dynamic assessment of TCR transmembrane conformational states linked to T cell functionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$882,500September 24, 2018August 31, 2024REINHERZ, ELLIS Lreporter.nih.gov
Development, Optimization and Preclinical Modeling of Hematopoietic Stem Cell Gene Editing for the Treatment of RAG1 ImmunodeficiencyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$882,201June 8, 2021June 2, 2023GENOVESE, PIETROreporter.nih.gov
Single Molecule Detection of L1 Insertions and IntermediatesNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$878,631April 1, 2023March 31, 2025BURNS, KATHLEEN Hreporter.nih.gov
Transcriptional control of gut epithelial homeostasis and regenerationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$878,354September 1, 2009March 31, 2024SHIVDASANI, RAMESH Areporter.nih.gov
Elucidating the molecular and cellular mechanisms of immune evasion in pancreatic cancerNIHNational Cancer Institute2022 to 2025$864,895July 1, 2022June 30, 2027FREED-PASTOR, WILLIAM Areporter.nih.gov
Characterizing the XRN1 exoribonuclease as a therapeutic target in non-small cell lung cancerNIHNational Cancer Institute2021 to 2025$861,782July 1, 2021August 1, 2025ZOU, TAOreporter.nih.gov
New approaches to targeting cell cycle proteins for cancer treatmentNIHNational Cancer Institute2025$855,249September 1, 2025July 31, 2032SICINSKI, PETERreporter.nih.gov
Cellular and Biochemical Pathways of Adipose Metabolism and ThermogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$840,198July 21, 2025April 30, 2029SPIEGELMAN, BRUCE M.reporter.nih.gov
ACTIVATE: AI-driven Clinical Trial Information and Viability Assessment Tool for EHRsNIHNational Cancer Institute2025$833,467September 17, 2025August 31, 2030KEHL, KENNETH Lreporter.nih.gov
Immunologic mechanisms that prevent autoimmunityNIHNational Institute of Allergy and Infectious Diseases2021$816,829July 6, 2020January 31, 2024CANTOR, HARVEYreporter.nih.gov
Integrative Somatic and Germline Computational Biology to Redefine Clinical Actionability in Solid TumorsNIHNational Cancer Institute2021 to 2022$814,350June 1, 2018May 31, 2023VAN ALLEN, ELIEZER Mreporter.nih.gov
Structural Basis of Thermogenic Mitochondrial Respiratory Complexes AssemblyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$813,511July 21, 2025April 30, 2029PUIGSERVER, PEREreporter.nih.gov
Harnessing the repetitive genome for cancer immunotherapyNIHNational Cancer Institute2023 to 2025$806,256August 1, 2023July 31, 2028GRIFFIN, GABRIEL K.reporter.nih.gov
Targeting DOT1L for Degradation in MLL-rearranged LeukemiaNIHNational Cancer Institute2021 to 2022$800,072September 25, 2012May 31, 2023ARMSTRONG, SCOTT Areporter.nih.gov
Liquid biopsy in myeloma to inform outcome and treatment decisionsNIHNational Cancer Institute2023 to 2024$793,992January 10, 2023August 31, 2024LOHR, JENS Greporter.nih.gov
The Young Empowered Scientists for ContinUed Research Engagement (YES for CURE) Program at the Dana-Farber/Harvard Cancer Center (DF/HCC)NIHNational Cancer Institute2024 to 2025$777,512August 8, 2024July 31, 2029DECAPRIO, JAMES A.reporter.nih.gov
Resistance and Sensitivity to MET Inhibitors in Lung CancerNIHNational Cancer Institute2021 to 2022$772,998February 1, 2018January 31, 2023JANNE, PASI Areporter.nih.gov
KDM5 histone lysine demethylases as potential novel myeloid tumor suppressorsNIHNational Cancer Institute2021 to 2022$765,490July 1, 2018June 30, 2024LOSMAN, JULIE-AUROREreporter.nih.gov
Understanding and addressing sub-optimal responses to CAR T cell therapy for Multiple MyelomaNIHNational Cancer Institute2021 to 2023$758,211August 1, 2019July 31, 2024SMITH, ERIC Lreporter.nih.gov
Tracing the Evolution of Chronic Lymphocytic Leukemia to Richter's Syndrome: Defining TransformationNIHNational Cancer Institute2022 to 2025$756,000September 1, 2022August 31, 2027PARRY, ERIN Mreporter.nih.gov
Enrichment of the State-1 Conformation of the HIV-1 Envelope GlycoproteinNIHNational Institute of Allergy and Infectious Diseases2021$750,826January 17, 2019December 31, 2022SODROSKI, JOSEPH Greporter.nih.gov
De novo design of small-molecule-binding proteinsNIHNational Institute of General Medical Sciences2022 to 2024$747,000July 15, 2020July 31, 2025POLIZZI, NICHOLASreporter.nih.gov
Deep clinical trajectory modeling to optimize accrual to cancer clinical trialsNIHNational Cancer Institute2022 to 2024$746,997February 1, 2020January 31, 2026KEHL, KENNETH Lreporter.nih.gov
Mechanistic characterization of the anti-inflammatory function of thermogenic fat for the treatment of metabolic disordersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$737,040March 15, 2022March 14, 2026MILLS, EVANNA LOUISAreporter.nih.gov
Interrogating and rewiring cell signaling pathways in CAR-T cells with synthetic phosphotyrosine recognition domainsNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2024$732,593September 15, 2020January 31, 2025ZHOU, XINreporter.nih.gov
Characterizing genetic risk of cancer across diverse populations through multi-ancestry epigenome profiling and chromatin QTL discoveryNIHNational Cancer Institute2025$720,252April 1, 2025March 31, 2030BACA, SYLVAN C.reporter.nih.gov
Hematopoietic stem cell gene therapy for infantile neuronal ceroid lipofuscinosisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2022$717,826August 21, 2018April 30, 2023WILLIAMS, DAVID Areporter.nih.gov
Expression and Impact of Interspersed RepeatsNIHNational Institute of General Medical Sciences2021 to 2022$708,000July 24, 2019May 31, 2023BURNS, KATHLEEN Hreporter.nih.gov
Single Molecule Detection of L1 Insertions and IntermediatesNIHNational Institute of Neurological Disorders and Stroke2025$704,816April 1, 2023March 31, 2028BURNS, KATHLEEN Hreporter.nih.gov
The Center for Therapeutic Targeting of EWS-oncoproteinsNIHNational Cancer Institute2021 to 2022$703,677September 7, 2022June 30, 2024STEGMAIER, KIMBERLYreporter.nih.gov
Improving prognosis prediction and therapy selection for cutaneous squamous cell carcinomas using artificial intelligenceNIHNational Institute of Biomedical Imaging and Bioengineering2024$693,156August 1, 2024July 31, 2027LOTTER, WILLIAM EDWARDreporter.nih.gov
Survival Data Analysis using general censoring-free incident rateNIHNational Institute of General Medical Sciences2024 to 2025$681,850March 1, 2024February 29, 2028UNO, HAJIMEreporter.nih.gov
Precision Assessment and Delivery of Cancer Risks in BRCA 1/2 Mutation CancersNIHNational Cancer Institute2021$676,046September 18, 2017August 31, 2023REBBECK, TIMOTHY Rreporter.nih.gov
Distance-based Exercise to preserve Function and prevENt Disability (DEFEND)NIHNational Cancer Institute2024 to 2025$673,907September 18, 2024August 31, 2027LIGIBEL, JENNIFER A.reporter.nih.gov
The Impact of Donor Hematopoietic DNMT3A Mutations in Stem Cell Transplant RecipientsNIHNational Cancer Institute2021 to 2023$659,712September 1, 2021July 14, 2024GIBSON, CHRISTOPHER JAMESreporter.nih.gov
Prevention of HIV-1 transmission by small-molecule CD4-mimetic entry inhibitorsNIHNational Institute of Allergy and Infectious Diseases2021$651,658July 14, 2017June 30, 2024MADANI, NAVIDreporter.nih.gov
Mapping the epigenetic dynamics of prostate cancer progression: integrating liquid biopsies and single-cell epigenomics for early detection of lineage plasticity and clinical decision-makingNIHNational Cancer Institute2025$627,474March 1, 2025February 28, 2030FREEDMAN, MATTHEW Lreporter.nih.gov
MUC1-C Oncoprotein Evades Immune Destruction in Non-small Cell Lung CancerNIHNational Cancer Institute2021$618,912April 1, 2012March 31, 2022KUFE, DONALD W.reporter.nih.gov
Improving response prediction to neoadjuvant therapy in pancreatic cancerNIHNational Cancer Institute2023 to 2025$605,166September 15, 2023October 1, 2025SINGH, HARSHABADreporter.nih.gov
A Novel Intervention for Avoidance-Related Opioid Misuse in Patients with CancerNIHNational Cancer Institute2022 to 2025$604,958July 1, 2022June 30, 2027YUSUFOV, MIRYAMreporter.nih.gov
DMS/NIGMS 1: Statistical modeling and estimation of cellular population dynamicsNIHNational Institute of General Medical Sciences2021 to 2023$599,997September 22, 2021July 31, 2025MCDONALD, THOMASreporter.nih.gov
Molecular Dynamics of Glioma Formation and DNA Damage Response by Mutant IDH1NIHNational Cancer Institute2024 to 2025$598,806May 6, 2024August 31, 2025SHI, DIANAreporter.nih.gov
The Center for Synovial Sarcoma Biology and TherapeuticsNIHNational Cancer Institute2021 to 2023$586,110April 1, 2023June 30, 2024KADOCH, CIGALLreporter.nih.gov
Dissecting the role of DNA damage repair deficiency in Ewing sarcoma pathogenesis for improved risk stratification and treatmentNIHNational Cancer Institute2023 to 2025$579,581September 19, 2023August 31, 2028GILLANI, RIAZreporter.nih.gov
Young Empowered Scientists for ContinUed Research Engagement (YES for CURE)NIHNational Cancer Institute2021 to 2023$575,729September 19, 2017August 31, 2024DECAPRIO, JAMES A.reporter.nih.gov
Unlocking the Potential of PI3K Inhibition in CLLNIHNational Cancer Institute2021$571,051March 1, 2017February 28, 2023BROWN, JENNIFER Rreporter.nih.gov
Systematic interrogation of the pancreatic cancer microenvironment in patient-derived specimensNIHNational Cancer Institute2021$568,413September 30, 2017August 31, 2022HAHN, WILLIAM C.reporter.nih.gov
MYB family alterations in pediatric gliomasNIHNational Cancer Institute2021$554,504April 1, 2017March 31, 2023LIGON, KEITH LLOYDreporter.nih.gov
The roles of anti-apoptotic proteins BCL-XL and MCL1 in mediating survival of high-grade serous ovarian cancer following drug-induced DNA damageNIHNational Cancer Institute2021 to 2023$553,020July 1, 2019June 30, 2025STOVER, ELIZABETH HARMONreporter.nih.gov
Spatial considerations in neuronal survival signalsNIHNational Institute of Neurological Disorders and Stroke2021$545,358August 15, 2005April 30, 2023SEGAL, ROSALIND A.reporter.nih.gov
(PQ8) Genetically faithful murine models for studying disease progression in chronic lymphocytic leukemiaNIHNational Cancer Institute2021$538,977May 11, 2017April 30, 2022WU, CATHERINE JU-YINGreporter.nih.gov
Functions of Cyclin/CDK complexes in development and cancerNIHNational Cancer Institute2021 to 2023$538,854September 11, 2019August 31, 2024GENG, YANreporter.nih.gov
Disseminating an Evidence-Based Tobacco Control intervention for School Teachers in IndiaNIHNational Cancer Institute2021$538,246January 17, 2017December 31, 2023SORENSEN, GLORIAN Creporter.nih.gov
Regulation of androgen receptor signaling in prostate cancer by protein arginine methylationNIHNational Cancer Institute2025$536,161April 1, 2023March 31, 2028VISWANATHAN, SRINIVAS RAGHAVANreporter.nih.gov
Summer Program to Advance Research Careers (SPARC)NIHNational Cancer Institute2021 to 2022$528,906September 8, 2017August 31, 2024BENZ, EDWARD Jreporter.nih.gov
PediQUEST: Improving Children's Quality of Life through e-PROMS and Palliative CareNIHNational Institute of Nursing Research2021$524,144June 8, 2017December 31, 2022WOLFE, JOANNEreporter.nih.gov
Targeting iron metabolism in pancreatic adenocarcinoma to overcome KRAS inhibitor therapeutic resistanceNIHNational Cancer Institute2025$523,480April 2, 2025March 31, 2030MANCIAS, JOSEPH Dreporter.nih.gov
Exploiting a Novel DNA Repair Defect in Ewing SarcomaNIHNational Cancer Institute2025$523,292December 4, 2024November 30, 2029D'ANDREA, ALAN D.reporter.nih.gov
Validation and implementation of ctDNA as a clinically informative biomarkerin AYAs with sarcomas.NIHNational Cancer Institute2024 to 2025$506,847August 1, 2024July 31, 2029SHULMAN, DAVIDreporter.nih.gov
Thermogenic chromatin remodeling control and fat tissue communicationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$503,865August 15, 2008March 31, 2023PUIGSERVER, PEREreporter.nih.gov
Calling germline and mosaic variants from long genomic and RNA-seq readsNIHNational Human Genome Research Institute2025$501,618September 1, 2025June 30, 2029LI, HENGreporter.nih.gov
Dissecting Therapeutic Resistance and Progression in Metastatic Melanoma Through Clinical Computational OncologyNIHNational Cancer Institute2021 to 2022$501,590September 18, 2018August 31, 2023LIU, DAVIDreporter.nih.gov
BCOR/PRC1.1 Inactivation In Splicing Factor Mutant MDS ProgressionNIHNational Cancer Institute2024 to 2025$501,014April 8, 2024March 31, 2029VEDULA, RAHULreporter.nih.gov
Regulating proliferation and differentiation of erythroid progenitorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$495,720July 1, 2020January 8, 2024LI, HOJUNreporter.nih.gov
Reducing viral reservoirs by opening HIV-1 Env to antibody attackNIHNational Institute of Allergy and Infectious Diseases2021$495,256February 15, 2017August 31, 2023SODROSKI, JOSEPH Greporter.nih.gov
Formation and function of pathologic stress granules containing RNA-Binding Protein SFPQ in tauopathyNIHNational Institute on Aging2023 to 2024$489,500January 15, 2023December 31, 2024SEGAL, ROSALIND A.reporter.nih.gov
Empowering NMR Utilization in Mechanistic Biology: Extending Size Limits and Catalyzing AutomationNIHNational Institute of General Medical Sciences2025$489,500August 1, 2025May 31, 2030ARTHANARI, HARIBABUreporter.nih.gov
Integrative molecular dissection of acquired resistance to PD1/PD-L1 blockade in localized and metastatic urothelial carcinomaNIHNational Cancer Institute2021$476,334May 1, 2021April 30, 2023SONPAVDE, GURUreporter.nih.gov
Workshop on Research Methods in Supportive OncologyNIHNational Cancer Institute2021 to 2025$475,557July 1, 2014January 31, 2030ROSENBERG, ABBY Rreporter.nih.gov
Integration of early genetic alterations and inflammation in gastroesophageal premalignancyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$474,120April 1, 2019January 31, 2024SETHI, NILAYreporter.nih.gov
Development of A Mindfulness-Based Mobile Health Intervention for Patients Coping with Pain from Advanced MalignanciesNIHNational Cancer Institute2022 to 2023$469,319April 1, 2022September 30, 2024ENZINGER, ANDREA Creporter.nih.gov
Sexual Health and Rehabilitation (SHARE): An Online Educational Intervention for Young Adult Female Cancer SurvivorsNIHNational Cancer Institute2024 to 2025$468,952June 1, 2024May 31, 2027BOBER, SHARON L.reporter.nih.gov
Combined bromodomain and CDK4/6 inhibition in NUT Carcinoma and other solid tumorsNIHNational Cancer Institute2023 to 2024$463,885February 1, 2023January 31, 2025CHENG, MICHAEL L.reporter.nih.gov
Expectations for Pediatric Cancer Treatment (EXPECT): A Family-Centered Intervention to Prepare Parents for Pediatric Leukemia TherapyNIHNational Cancer Institute2021 to 2023$456,685September 19, 2019February 28, 2025GREENZANG, KATIE A.reporter.nih.gov
Mesenchymal regulation of fetal intestinal development and adult regenerationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$455,985July 17, 2020September 15, 2024MCCARTHY, NEILreporter.nih.gov
Advanced Workshop on Research Skills in OncologyNIHNational Cancer Institute2023 to 2025$455,140April 1, 2020August 31, 2028THOMAS, JANE DELIMAreporter.nih.gov
Defining the impact of mutational drivers on the immune microenvironment of CLLNIHNational Cancer Institute2022 to 2023$453,523February 1, 2022January 31, 2024WU, CATHERINE JU-YINGreporter.nih.gov
Sleep Treatment Education Program-1 (STEP-1): A Randomized Trial of a Self-Management Insomnia Intervention for Cancer SurvivorsNIHNational Cancer Institute2022 to 2023$453,523July 1, 2022June 30, 2025RECKLITIS, CHRISTOPHER JOHNreporter.nih.gov
Translation initiation as a therapeutic target in neuroblastomaNIHNational Cancer Institute2023 to 2024$453,511December 15, 2022November 30, 2024GEORGE, RANI E.reporter.nih.gov
Investigating Interactions Between Radiation and Antibody-Drug Conjugates in Bladder CancerNIHNational Cancer Institute2024 to 2025$452,851April 1, 2024March 31, 2026MOUW, KENT Wreporter.nih.gov
Prolonged Nightly Fasting as a Behavioral Intervention for Obesity Reduction and the Prevention of Progression in Precursor Multiple MyelomaNIHNational Cancer Institute2022 to 2023$452,690June 3, 2022May 31, 2025MARINAC, CATHERINEreporter.nih.gov
Targeting the DNA Damage Response in CDK12-Mutant Prostate CancerNIHNational Cancer Institute2021 to 2022$451,611July 1, 2021June 30, 2023MOUW, KENT Wreporter.nih.gov
Chemical manipulation of creatine kinases to treat acute myeloid leukemiaNIHNational Cancer Institute2021$450,655April 1, 2021September 30, 2023CHOUCHANI, EDWARD THOMASreporter.nih.gov
MUC1-C is a target for advancing immunotherapy of non-small cell lung cancerNIHNational Cancer Institute2024$450,429June 14, 2024May 31, 2026KUFE, DONALD W.reporter.nih.gov
STEP-YA: An Online Self-Management Intervention for Young Adult Cancer Survivors with InsomniaNIHNational Cancer Institute2022 to 2023$450,340June 1, 2022May 31, 2025RECKLITIS, CHRISTOPHER JOHNreporter.nih.gov
Genetic dissection of neural pathways that modulate systemic inflammationNIHNational Center for Complementary & Integrative Health2021$445,000September 16, 2019August 31, 2022MA, QIUFUreporter.nih.gov
Molecular mechanisms of DNA double strand break repair by homologous recombinationNIHNational Institute of General Medical Sciences2025$445,000January 22, 2025December 31, 2029STINSON, BENJAMIN Mreporter.nih.gov
SESORRS endoscopy for the staging and evaluation of colorectal cancerNIHNational Cancer Institute2024 to 2025$444,793June 8, 2022December 31, 2026NICOLSON, FAYreporter.nih.gov
Targeting MUC1-C with an antibody drug conjugate for the therapy of advanced prostate cancerNIHNational Cancer Institute2022$442,214September 22, 2022August 31, 2025KUFE, DONALD W.reporter.nih.gov
Targeting MUC1-C for the Treatment of Small Cell Lung Cancer ProgressionNIHNational Cancer Institute2022 to 2023$436,966February 4, 2022December 31, 2023KUFE, DONALD W.reporter.nih.gov
Epigenetic regulators define a dynamic chromatin landscape in NUP98-rearranged leukemiaNIHNational Cancer Institute2024 to 2025$430,358April 1, 2024February 28, 2029HEIKAMP, EMILYreporter.nih.gov
Regulation of the follicular T-cell response to autoimmunityNIHNational Institute of Allergy and Infectious Diseases2021$429,521April 1, 2000November 30, 2022CANTOR, HARVEYreporter.nih.gov
Academic Career Skills for Junior Faculty ResearchersNIHNational Cancer Institute2021 to 2022$420,692April 1, 2020August 31, 2023PIRL, WILLIAM Freporter.nih.gov
Exploring alternate targets for inhibition of virus infection by PPI disruptionNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$419,995February 22, 2021January 31, 2024CALDERWOOD, MICHAEL Areporter.nih.gov
The ALK receptor tyrosine kinase as a therapeutic target in neuroblastomaNIHNational Cancer Institute2021$413,844January 1, 2011February 28, 2023GEORGE, RANI E.reporter.nih.gov
Impact of preanalytical conditions on functional cancer biomarkersNIHNational Cancer Institute2025$406,351December 1, 2025November 30, 2030BHOLA, PATRICKreporter.nih.gov
Insights from somatic genomics lead to novel therapeutic targets in inherited bone marrow failure syndromes: Shwachman-Diamond Syndrome as a model.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$406,143July 1, 2021August 31, 2023KENNEDY, ALYSSAreporter.nih.gov
Development and Pilot Testing of a Collaborative Agenda-Setting Intervention to Promote Patient-Centered Communication in Ovarian Cancer CareNIHNational Institute of Nursing Research2023 to 2025$401,474May 15, 2023April 30, 2027POZZAR, RACHELreporter.nih.gov
Integrative modelling of single-cell data to elucidate the genetic architecture of complex diseaseNIHNational Human Genome Research Institute2023$400,000September 21, 2023July 31, 2024GUSEV, ALEXANDERreporter.nih.gov
Dissecting the Pathogenesis of Ewing Sarcoma with Integrative GenomicsNIHNational Cancer Institute2021$396,547January 1, 2017June 30, 2022STEGMAIER, KIMBERLYreporter.nih.gov
Investigating 53BP1 'dephosphorylation' as a critical determinant of PARPNIHNational Cancer Institute2021$384,923March 15, 2017February 28, 2023CHOWDHURY, DIPANJANreporter.nih.gov
Repurposing Metformin for the Prevention of Disease Progression in Precursor Multiple MyelomaNIHNational Cancer Institute2021 to 2022$384,480September 1, 2020February 29, 2024MARINAC, CATHERINEreporter.nih.gov
Perturbation based single cell investigation of tumor micro-environmentNIHNational Cancer Institute2022 to 2025$380,515August 3, 2020July 31, 2026ZHANG, CHIreporter.nih.gov
Investigating Immune Responses to Neoantigen Cancer Vaccines using In Vivo Functionalized LineageNIHNational Cancer Institute2022 to 2025$376,785February 1, 2022December 31, 2025ROBLES-OTEIZA, CAMILAreporter.nih.gov
Inhibitor-sensitive and -resistant EGFR mutants from lung cancer and glioblastomaNIHNational Cancer Institute2021 to 2022$368,739March 24, 2006March 31, 2023ECK, MICHAEL Jreporter.nih.gov
Degrading therapeutically important kinases using small moleculesNIHNational Cancer Institute2021$365,491December 1, 2018March 31, 2021GRAY, NATHANAEL SCHIANDERreporter.nih.gov
Targeting Oncogenic Drivers in CancerNIHNational Cancer Institute2022 to 2025$365,310March 7, 2022February 28, 2026BOUDREAU, MATTHEW Wreporter.nih.gov
Effects of Extracellular Mechanics on Mechanosensory and Central Neuron FunctionNIHNational Institute on Aging2022 to 2025$358,155September 23, 2019December 31, 2025FRANCO, JOY ANNreporter.nih.gov
New Chemical Tools for Covalent Drug DiscoveryNIHNational Cancer Institute2024 to 2025$354,873February 1, 2024June 1, 2025MARTO, JARROD A.reporter.nih.gov
Targeting mitochondrial one carbon folate metabolism for novel T-cell acute lymphoblastic leukemia therapyNIHNational Cancer Institute2021 to 2022$354,240February 15, 2018January 31, 2023PIKMAN, YANAreporter.nih.gov
The Promoting Resilience in Stress Management (PRISM) Intervention: a multi-site randomized controlled trial for Adolescents and Young Adults with advanced cancerNIHNational Cancer Institute2023$351,683July 29, 2023July 31, 2025ROSENBERG, ABBY Rreporter.nih.gov
Defining the landscape and mechanisms of protein redox regulation during agingNIHNational Institute on Aging2021$343,865April 15, 2021March 31, 2022CHOUCHANI, EDWARD THOMASreporter.nih.gov
Mitochondrial Protein Translation Signaling and Survival MechanismsNIHNational Institute on Aging2021$337,842September 1, 2021November 30, 2023PUIGSERVER, PEREreporter.nih.gov
Modeling and Dissecting Epigenetic Drivers of GliomagenesisNIHNational Cancer Institute2022 to 2023$334,800March 1, 2022August 31, 2023RAHME, GILBERT Jreporter.nih.gov
Identifying metabolic regulation of T cells during early childhood developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$330,480April 1, 2024March 31, 2029ROWE, JARED H.reporter.nih.gov
Inflammatory Disease Associations in Clonal HematopoiesisNIHNational Heart, Lung, and Blood Institute2024 to 2025$330,112September 1, 2024August 31, 2029WEEKS, LACHELLE DAWNreporter.nih.gov
Dissecting the Role of Germline Genetics in RAS-Driven CancersNIHNational Cancer Institute2024 to 2025$327,456February 1, 2024August 31, 2025COLLINS, RYAN LEWISreporter.nih.gov
The Role of Mitochondrial TNAP in Adaptive ThermogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$327,368December 1, 2022August 8, 2025SUN, YIZHIreporter.nih.gov
Tools for DUB Drug DiscoveryNIHNational Cancer Institute2021$323,910May 15, 2020April 30, 2023MARTO, JARROD A.reporter.nih.gov
Integrating pain-CBT into an mHealth analgesic support intervention for patients withchronic pain from advanced cancersNIHNational Cancer Institute2024 to 2025$319,265December 17, 2024June 30, 2027HILTON, DESIREE Rreporter.nih.gov
Investigating molecular mechanism of immune response during cancer progressionNIHNational Cancer Institute2021 to 2024$316,083September 8, 2018November 30, 2024CHEN, ZEYUreporter.nih.gov
Obesity and Pancreatic Cancer Progression and SurvivalNIHNational Cancer Institute2021 to 2022$299,393July 4, 2018June 30, 2024BABIC, ANAreporter.nih.gov
Improving Hospice Use for Patients with Blood CancersNIHNational Cancer Institute2021 to 2022$296,978September 1, 2017May 31, 2023ODEJIDE, OREOFE OLUKEMIreporter.nih.gov
Functional Characterization of HER Family Variant Biology and Resistance in CancerNIHNational Cancer Institute2021 to 2022$285,984September 15, 2021August 31, 2023HAYES, TIKVAH Kreporter.nih.gov
Integrative Prediction of Therapeutic Response in T-cell Lymphoma by Omic and Spatial ModelingNIHNational Cancer Institute2021 to 2022$272,160March 1, 2021February 28, 2023NIRMAL, AJIT JOHNSONreporter.nih.gov
Characterizing the role of MARCH5 in apoptosis regulation in acute myeloid leukemiaNIHNational Cancer Institute2021 to 2022$272,160August 23, 2021July 31, 2023LIN, SHANreporter.nih.gov
Targeting mechanical regulation of monocyte fate in head and neck cancer.NIHNational Institute of Dental & Craniofacial Research2021 to 2022$270,000April 1, 2021June 30, 2022VINING, KYLE HOLMBERGreporter.nih.gov
In vivo testing of an agonistic anti-GITR mAb that induces cell surface clustering to augment signal transduction and a 2nd Gen bispecific anti-GITR/PD1 Ab derivative for improved anti-tumor activityNIHNational Cancer Institute2024$268,059February 1, 2024January 31, 2027MARASCO, WAYNE A.reporter.nih.gov
Targeting the CDK4/6 pathway in MiT/TFE-translocation renal cell carcinomaNIHNational Cancer Institute2025$267,298February 1, 2025January 31, 2027VISWANATHAN, SRINIVAS RAGHAVANreporter.nih.gov
SESORRS endoscopy for the staging and evaluation of colorectal cancerNIHNational Cancer Institute2022 to 2023$266,978June 8, 2022December 31, 2023NICOLSON, FAYreporter.nih.gov
Targeting Menin Protein Stability In AMLNIHNational Cancer Institute2023 to 2024$259,200July 18, 2023February 28, 2025CUTLER, JEVONreporter.nih.gov
Targeting mitochondrial vulnerabilities to drive intrinsic melanoma immunogenicityNIHNational Cancer Institute2024 to 2025$257,596April 4, 2024July 1, 2025LIANG, JIAXINreporter.nih.gov
Collaborative Care to Improve Resilience and Quality of Life among Youth with Non-malignant Blood DisordersNIHNational Heart, Lung, and Blood Institute2024 to 2025$252,946September 1, 2024August 31, 2029ROSENBERG, ABBY Rreporter.nih.gov
Defining clinically relevant transcriptional networks in gastrointestinal stromal tumorNIHNational Cancer Institute2021 to 2022$251,631August 1, 2020August 31, 2022HEMMING, MATTHEWreporter.nih.gov
Mechanistic Determinants of Follicular-Helper T-cell LymphomagenesisNIHNational Cancer Institute2021$250,577July 1, 2019June 30, 2022NG, SAMUEL YAO-MINGreporter.nih.gov
Dissecting the Role of Germline Genetics in RAS-Driven CancersNIHNational Cancer Institute2025$248,999February 1, 2024August 31, 2028COLLINS, RYAN LEWISreporter.nih.gov
Memory-like NK cells for enhanced immunotherapy of post transplant relapse in patients with myeloid malignanciesNIHNational Cancer Institute2021$248,243January 1, 2020December 31, 2021ROMEE, RIZWANreporter.nih.gov
Immune Evasion through HLA-E in Diffuse Large B-Cell Lymphoma: Defining Its Regulation and Cellular InteractionsNIHNational Cancer Institute2025$241,884September 3, 2025August 31, 2030HAHN, CYNTHIAreporter.nih.gov
Advancing WRN as a synthetic lethal target for microsatellite unstable CancersNIHNational Cancer Institute2021$237,994September 1, 2021August 31, 2022CHAN, EDMONDreporter.nih.gov
Elucidating the Mechanisms of Translational Approaches to Enhance Recovery of Aged MuscleNIHNational Institute on Aging2023 to 2025$237,953September 15, 2021August 31, 2027PETROCELLI, JONATHAN JOSEPHreporter.nih.gov
Mechanism of Action of Spautin-1, A Novel Degrader of IKZF1NIHNational Cancer Institute2021$228,182July 1, 2020June 30, 2022KODURI, VIDYASAGARreporter.nih.gov
Determining Mechanisms and Measures for the Design of Chemotherapy-Induced Peripheral Neuropathy Clinical Trials in Adolescents and Young Adults with CancerNIHNational Institute of Nursing Research2021 to 2022$227,399May 4, 2020October 31, 2023KNOERL, ROBERT JAMESreporter.nih.gov
Deciphering non-canonical translation in high risk medulloblastomaNIHNational Cancer Institute2022$226,800September 1, 2022March 31, 2023PRENSNER, JOHNreporter.nih.gov
Targeting the cancer neo-genome for destruction with CRISPR-Cas enzymesNIHNational Cancer Institute2023 to 2025$221,404July 1, 2023June 30, 2026LEIBOWITZ, MITCHELL Lreporter.nih.gov
Fast-kinetics approaches to define direct gene-regulatory functions of MYB in leukemiaNIHNational Cancer Institute2023$220,792August 1, 2023December 12, 2023PIMKIN, MAXIMreporter.nih.gov
Defining the landscape and mechanisms of redox regulation of metabolism during agingNIHNational Institute on Aging2022 to 2023$219,858May 15, 2022December 31, 2024XIAO, HAOPENGreporter.nih.gov
Biomaterial Drones for Image-Guided Drug Delivery during radiotherapyNIHNational Cancer Institute2021$211,789February 15, 2019June 30, 2021NGWA, WILFREDreporter.nih.gov
Lipid metabolism as a therapeutic vulnerability in BET inhibitor-resistant medulloblastomaNIHNational Cancer Institute2021 to 2023$205,268April 1, 2021March 31, 2024LUPIEN, LESLIEreporter.nih.gov
Cancer Therapeutic Resistance: Implication of AcAPE1 Mediated DNA Repair and T-Cell Based ImmunotherapyNIHNational Cancer Institute2021 to 2022$204,178September 1, 2019August 31, 2023ROYCHOUDHURY, SHRABASTIreporter.nih.gov
Fertility legislation and unmet needs: Exploring intervenable barriers for quality oncofertility care among adolescent and young adult cancer patientsNIHNational Cancer Institute2024 to 2025$202,342September 1, 2023April 30, 2028STAL, JULIAreporter.nih.gov
Targeting ALK through Degradation and Allosteric InhibitorsNIHNational Cancer Institute2021$199,385May 15, 2009March 31, 2021GRAY, NATHANAEL SCHIANDERreporter.nih.gov
Elucidating novel molecular mechanisms of irisin-mediated effects via integrinNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$196,102May 1, 2022December 31, 2024A, MUreporter.nih.gov
The role of CMTR2 in Lung CancerNIHNational Cancer Institute2021 to 2022$195,178September 21, 2016December 31, 2023YERMALOVICH, ALENAreporter.nih.gov
Metabolically active macrophages: a novel link between obesity and triple negative breast cancerNIHNational Cancer Institute2021 to 2022$195,178December 21, 2018November 30, 2023TIWARI, PAYALreporter.nih.gov
Elucidating the role of RNA splicing in the metastatic seeding and outgrowth of aggressive cancers.NIHNational Cancer Institute2024 to 2025$193,342July 13, 2022June 30, 2028PARKER, KIMBERLYreporter.nih.gov
SIRT1 Regulates RNA Stability to Promote Breast CancerNIHNational Cancer Institute2024 to 2025$193,342August 1, 2022May 31, 2028WANG, FANGYUreporter.nih.gov
Noninvasive monitoring and evaluation of anti-tumor responses as a predictive toolNIHNational Cancer Institute2021$191,276June 1, 2019May 31, 2022RASHIDIAN, MOHAMMADreporter.nih.gov
Structural biology and drug discovery targeting oncogenic EGFR and BRAF kinasesNIHNational Cancer Institute2021$188,413September 19, 2017July 22, 2022PARK, EUNYOUNGreporter.nih.gov
Translational regulation of PGC1alpha and oxidative metabolismNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$180,000May 1, 2021April 30, 2024DUMESIC, PHILLIP ANTHONYreporter.nih.gov
Mechanisms of mitochondrial-ER communication during dietary and thermal induced stressNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$180,000July 1, 2023June 30, 2025LATORRE MURO, PEDRO ANTONIOreporter.nih.gov
A Preventive Care Approach to Mitigate the Impact of Pediatric ALL Treatment on SleepNIHNational Cancer Institute2021 to 2022$178,000April 1, 2021March 31, 2024ZHOU, ERIC Sreporter.nih.gov
Repurposing Bruton's tyrosine kinase (BTK) inhibitors to reverse immunosuppression in high-grade serous ovarian cancer (HGSC)NIHNational Cancer Institute2022 to 2023$178,000July 7, 2022June 30, 2024GLIMCHER, LAURIE HOLLISreporter.nih.gov
Overcoming resistance in BCR-ABL-rearranged acute lymphoblastic leukemiaNIHNational Cancer Institute2021$177,120August 1, 2017July 31, 2022MURAKAMI, MARK A.reporter.nih.gov
Functional interrogation of epigenetic vulnerabilities in KRAS-mutant pancreatic cancerNIHNational Cancer Institute2021$177,120September 1, 2017August 31, 2022AGUIRRE, ANDREW JAMESreporter.nih.gov
New Therapeutic Targets in Small Cell Lung Cancer that are Epistatic or Synthetic Lethal with pRB LossNIHNational Cancer Institute2021$177,120September 19, 2017August 31, 2022OSER, MATTHEW GILBERTreporter.nih.gov
Investigating the effect of ERCC2 mutations on DNA repair capacity and chemo-radiotherapy response in muscle-invasive bladder cancerNIHNational Cancer Institute2021$176,947August 1, 2017July 31, 2022MOUW, KENT Wreporter.nih.gov
Curated prostate cancer data for novel and reproducible prognostic modelingNIHNational Cancer Institute2021$173,649March 1, 2020February 28, 2023TYEKUCHEVA, SVITLANAreporter.nih.gov
Resolving phenotypic overlap in renal carcinoma subtypes using multi-tiered network methodsNIHNational Cancer Institute2025$172,193May 7, 2025April 30, 2030BEN GUEBILA, MAROUENreporter.nih.gov
Dissecting the impact of tumor-immune spatial interactions in mismatch-repair stratified colorectal cancersNIHNational Cancer Institute2025$170,641August 1, 2025July 31, 2027WALA, JEREMIAHreporter.nih.gov
Uncovering Principles of Adaptive Regulation in Cancer Resistance Through Deep Evolutionary ProfilingNIHNational Cancer Institute2021$170,640July 1, 2020June 30, 2024RAVI, ARVINDreporter.nih.gov
The Role of Histone Cleavage in Breast CancerNIHNational Cancer Institute2025$170,640July 1, 2025June 30, 2027LI, ZHEQIreporter.nih.gov
Deep clinical trajectory modeling to optimize accrual to cancer clinical trialsNIHNational Cancer Institute2021$170,176February 1, 2020January 31, 2022KEHL, KENNETH Lreporter.nih.gov
Robust and cost-effective computational methods for haplotype-resolved genome assembliesNIHNational Human Genome Research Institute2023 to 2024$165,150February 13, 2023July 1, 2024CHENG, HAOYUreporter.nih.gov
Harnessing Exercise to Enhance Immunity and Boost Immunotherapy Outcomes in Patients with Lung CancerNIHNational Cancer Institute2024$163,448February 1, 2024December 31, 2024KANG, DONG-WOOreporter.nih.gov
Signaling pathways in tumoricidal macrophages in pancreatic cancerNIHNational Cancer Institute2025$159,304July 1, 2025June 30, 2027QIANG, LIreporter.nih.gov
CAREER: Synthesis and Application of Bioorthogonally Degradable PolymersNSFDivision Of Chemistry2023$157,741April 1, 2023November 30, 2024Justin Kimnsf.gov
The mechanistic study on irisin-mediated immune response and its role in adipose tissue dynamicsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$152,454January 1, 2025November 30, 2027A, MUreporter.nih.gov
Mitochondria mediated intercellular metabolic coupling in bone marrow regenerationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024$150,000September 1, 2024August 31, 2025CANCELAS, JOSE A.reporter.nih.gov
Mechanistic Understanding of Hypoxia-Induced Peroxisome loss: Implications for Heart FailureNIHNational Heart, Lung, and Blood Institute2022$149,850June 1, 2022June 30, 2023WYANT, GREGreporter.nih.gov
Defining PRC1.1 as a gatekeeper of lineage plasticity and response to anti-GD2 therapyNIHNational Cancer Institute2023$147,150May 9, 2023May 31, 2024MABE, NATHANIELreporter.nih.gov
Structure and Function of the SHOC2 Holophosphatase Complex in RAS-driven CancerNIHNational Cancer Institute2023$147,150May 1, 2023December 1, 2023KWON, JASONreporter.nih.gov
Identifying Combination Therapies in Ovarian Tumors using High Throughput Dynamic BH3 ProfilingNIHNational Cancer Institute2022 to 2023$143,574December 1, 2020March 31, 2024MCQUEENEY, KELLEYreporter.nih.gov
Evaluating the mechanism by which the DYNLL1-MRE11 complex regulates DNA end resection and genome stability.NIHNational Institute of General Medical Sciences2023 to 2024$143,364February 1, 2023January 31, 2025SWIFT, MICHELLEreporter.nih.gov
Defining IKZF1/IKAROS as an oncogene and therapeutic target in MLL-r AMLNIHNational Cancer Institute2021 to 2022$138,692June 1, 2020May 31, 2023CUTLER, JEVONreporter.nih.gov
Engineered Living Materials as Programmable Therapeutic Implants for Pancreatic CancerNIHNational Cancer Institute2025$137,995September 2, 2025August 31, 2026HARIMOTO, TETSUHIROreporter.nih.gov
Elucidating the Role of Epigenetic Plasticity in anti-GD2 Immunotherapy ResponseNIHNational Cancer Institute2021 to 2022$137,784June 1, 2021May 31, 2024MABE, NATHANIELreporter.nih.gov
Therapeutic Strategies to Prevent Small Cell Lung Cancer Histological TransformationNIHNational Cancer Institute2025$136,266July 14, 2025June 30, 2027LI, YIXIANGreporter.nih.gov
Structural Basis for Small Molecule-Mediated Allosteric Activation of Protein Phosphatase 2ANIHNational Cancer Institute2021$136,080May 3, 2021July 15, 2021MORITA, KENreporter.nih.gov
A pan-cancer atlas of driver mutations in >100,000 patients based on a hypothesis-driven combined computational and experimental approachNIHNational Cancer Institute2021$133,195August 16, 2021March 31, 2022DIETLEIN, FELIXreporter.nih.gov
Studies of mutant-selective allosteric inhibitors of EGFR for non-small cell lung cancerNIHNational Cancer Institute2021 to 2022$130,728June 4, 2020April 29, 2023BEYETT, TYLER STEVENreporter.nih.gov
Targeting casein kinase 1-alpha for cancer therapyNIHNational Cancer Institute2021$130,475July 6, 2018February 28, 2022CORSELLO, STEVEN MUNTEANreporter.nih.gov
The role of the mesenchymal niche in intestinal crypt fissionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024$125,700March 1, 2024September 15, 2024MCCARTHY, NEILreporter.nih.gov
Towards a structural understanding of transcriptional regulation by ZMYM2-KDM1A-CoRESTNIHNational Institute of General Medical Sciences2025$125,000December 18, 2024November 30, 2026WACHTER, FRANZISKAreporter.nih.gov
Identifying drug synergistic with cancer immunotherapyNIHNational Cancer Institute2021$120,038September 16, 2020December 31, 2022SAHU, AVINASH DASreporter.nih.gov
Revealing Cellular Determinants of LINE-1 Retrotransposition OutcomesNIHNational Institute of General Medical Sciences2025$109,448September 1, 2025August 31, 2027LAW, CHEUK-TINGreporter.nih.gov
The Role of E2F2 in HER2 Positive Breast CancerNIHNational Cancer Institute2021$104,406August 1, 2018July 31, 2022RENNHACK, JONATHANreporter.nih.gov
Evaluating METTL1-mediated m7G tRNA methylation as a novel dependency in alveolar rhadomyosarcomaNIHNational Cancer Institute2025$99,576September 1, 2023March 31, 2029WILKINSON, EMMA ANNEreporter.nih.gov
Exploiting Oncogenic Chromatin Regulators in Cancer Initiation and ProgressionNIHNational Cancer Institute2024$99,216September 1, 2021September 1, 2024HYDER, USMANreporter.nih.gov
Defining Therapeutically Targetable Regulators of Tumor-Intrinsic Immune Suppression in GlioblastomaNIHNational Cancer Institute2025$99,216February 7, 2025January 31, 2029JOHNSON, AMANDAreporter.nih.gov
BH3 Profiling in AML to Measure Apoptotic Signaling Kinetics of Approved Drugs and Identify Integrated Stress Response Apoptotic SusceptibilitiesNIHNational Cancer Institute2025$99,216August 10, 2023July 31, 2029UNG, JOHNSONreporter.nih.gov
Investigating IGF2BP1 as a novel Therapeutic Target for Ewing SarcomaNIHNational Cancer Institute2024 to 2025$95,155April 3, 2024July 25, 2025BOND, MICHAEL JOSEPHreporter.nih.gov
Mechanisms and therapeutic evaluation of splicing modulation for cohesin-mutant myelodysplastic syndromesNIHNational Heart, Lung, and Blood Institute2021 to 2022$95,149September 1, 2021January 31, 2023WHEELER, EMILYreporter.nih.gov
Targeting the Nrf2 pathway in cancerNIHNational Cancer Institute2021$93,462May 1, 2020May 14, 2021ZHANG, DIreporter.nih.gov
Understanding Ancestral Contribution to Lung AdenocarcinomaNIHNational Cancer Institute2021$91,460April 1, 2021January 15, 2022ZHANG, JIANreporter.nih.gov
Mechanistic characterization of the anti-inflammatory function of thermogenic fat for the treatment of metabolic disordersNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$90,000July 10, 2020March 1, 2022MILLS, EVANNA LOUISAreporter.nih.gov
Remodeling mitochondrial cristae to rescue bioenergetic defects in mitochondrial diseaseNIHNational Institute of General Medical Sciences2021 to 2022$88,702April 1, 2020June 10, 2022MUTLU, BESTEreporter.nih.gov
Expanding the understanding of tRNA lifecycle under cellular stressNIHNational Institute of General Medical Sciences2025$78,040September 1, 2025August 31, 2027WILLIAMS, ALLISONreporter.nih.gov
Elucidating the role of PATZ1 in MYCN-amplified neuroblastomaNIHNational Cancer Institute2025$78,040September 5, 2025September 4, 2028SOEUNG, MELINDAreporter.nih.gov
Dissecting the Structure of Oligomeric BAK and the Implications for Reactivating Apoptosis in CancerNIHNational Cancer Institute2025$75,520September 15, 2025September 14, 2027MA, MINH THU Hreporter.nih.gov
Interrogating the role of IFNgamma in promoting metastasis and immune evasion of triple negative breast cancerNIHNational Cancer Institute2025$75,520August 1, 2025July 31, 2028GETZLER, ADAM JOSHUAreporter.nih.gov
Examining the role of adenosine-sensing by macrophages in obesity-induced cardiac inflammationNIHNational Heart, Lung, and Blood Institute2025$75,052September 30, 2025September 29, 2028SPRENKLE, NEILreporter.nih.gov
Elucidating the role of the SAGA complex in MYCN-amplified neuroblastomaNIHNational Cancer Institute2021$74,886September 12, 2019September 11, 2022MALONE, CLARE FELICITYreporter.nih.gov
Mismatch Repair Proteins as Drivers of Temozolomide Resistance in GlioblastomaNIHNational Cancer Institute2021$70,458July 1, 2019June 30, 2022BOYNTON, ADAM NATHANIELreporter.nih.gov
Elucidating the role of SHOC2 to enhance MEK inhibitor sensitivity in pancreatic cancerNIHNational Cancer Institute2021$66,390July 1, 2019June 30, 2022KWON, JASONreporter.nih.gov
COVID Extension: Material Hardship as a Targetable Measure of Poverty in Pediatric CancerNIHNational Cancer Institute2021$63,388September 1, 2021February 28, 2022BONA, KIRA O.reporter.nih.gov
Deciphering the mechanisms regulating itaconate production and signaling in macrophagesNIHNational Institute of Allergy and Infectious Diseases2025$47,945September 1, 2025August 31, 2028TRAN, NHIENreporter.nih.gov
Role of PPM1D and PPM1D mutations in hematopoiesis and response to stressNIHNational Cancer Institute2021$46,239August 20, 2021January 1, 2022MILLER, PETER GRANTreporter.nih.gov
Conference: Symposium on the Immune System of BacteriaNSFDivision of Molecular and Cellular Biosciences2024$45,000March 1, 2024February 28, 2025Philip Kranzuschnsf.gov
SIMPRO Research Center: Integration and Implementation of PROs for Symptom ManageNIHNational Cancer Institute2023$42,500September 20, 2018August 31, 2024HASSETT, MICHAEL JAMESreporter.nih.gov
Unraveling the Mechanisms of Neoantigen Vaccine-Induced Epitope SpreadingNIHNational Cancer Institute2025$36,538July 1, 2025June 30, 2028RICHTERICH, CONNOR ANTONIOreporter.nih.gov
Epigenetic Induction of Gliomagenesis in Neural Progenitor CellsNIHNational Cancer Institute2021$27,562January 1, 2019July 2, 2022RAHME, GILBERT Jreporter.nih.gov
Contributions of tumor molecular subtypes to prostate cancer racial disparitiesNIHNational Cancer Institute2021$26,717February 1, 2020March 31, 2021KENSLER, KEVIN HUGHESreporter.nih.gov
Characterization of LINE-1 reverse transcriptase activityNIHNational Institute of General Medical Sciences2023$22,942February 2, 2023May 11, 2023SMAIL, BENEDICTreporter.nih.gov
Leveraging mHealth to deliver integrated pain-CBT, opioid monitoring, and self-management support for advanced cancer patients coping with chronic painNIHNational Cancer Institute2023$22,705October 7, 2024June 30, 2025AZIZODDIN, DESIREE Rreporter.nih.gov
Structural and functional investigation into protein degradation by the DCAF16 ubiquitin ligaseNIHNational Cancer Institute2021$15,515January 3, 2022February 18, 2022PUVAR, KEDARreporter.nih.gov
Symposium on the Immune System of BacteriaNIHNational Institute of Allergy and Infectious Diseases2024$7,500March 5, 2024February 28, 2025KRANZUSCH, PHILIP Jreporter.nih.gov
Investigating SLC46A3 as a negative regulator of nanoparticle drug deliveryNIHNational Cancer Institute2024$1July 5, 2024September 30, 2024STRAEHLA, JOELLE PAYNEreporter.nih.gov

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025221$176,991,6810$0
2024236$163,860,6621$45,000
2023233$162,771,6971$157,741
2022243$157,477,1800$0
2021253$160,221,2560$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 3 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 3 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 1 award here
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)PAR-27-089NIH93.398November 2, 2026Not listedSame assistance listing 93.398 as 106 awards here
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)PAR-27-088NIH93.398November 20, 2026Not listedSame assistance listing 93.398 as 106 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.398December 3, 2026Not listedSame assistance listing 93.398 as 106 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.398December 3, 2026Not listedSame assistance listing 93.398 as 106 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.398December 4, 2026Not listedSame assistance listing 93.398 as 106 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)RFA-LM-28-001NIH93.398February 11, 2027$775,000Same assistance listing 93.398 as 106 awards here
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)RFA-OD-25-003NIH93.398April 9, 2027$200,000Same assistance listing 93.398 as 106 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIH93.398May 7, 2027Not listedSame assistance listing 93.398 as 106 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIH93.398May 7, 2027Not listedSame assistance listing 93.398 as 106 awards here
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)PA-24-190NIH93.398May 7, 2027Not listedSame assistance listing 93.398 as 106 awards here
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)PA-24-191NIH93.398May 7, 2027Not listedSame assistance listing 93.398 as 106 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)PA-24-193NIH93.398May 7, 2027Not listedSame assistance listing 93.398 as 106 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)PA-24-181NIH93.398May 8, 2027Not listedSame assistance listing 93.398 as 106 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIH93.398July 17, 2027Not listedSame assistance listing 93.398 as 106 awards here
Investigator-Focused Award (Parent R35)PAR-28-037NIH93.398October 4, 2027Not listedSame assistance listing 93.398 as 106 awards here
NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)PAR-25-135NIH93.398October 14, 2027Not listedSame assistance listing 93.398 as 106 awards here
NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)PAR-25-313NIH93.398October 14, 2027Not listedSame assistance listing 93.398 as 106 awards here

Topics of its NIH awards

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.