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Stem Cell and Progenitor Cell Research: 3,819 NIH awards ($5.7B) to 378 organizations

3,819 NIH awards ($5.7B) in the NIH spending category Stem Cell and Progenitor Cell Research, to 378 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 3,819 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Washington National Primate Research CenterNIHOffice of the Director, National Institutes of Health2021 to 2025$66,616,318June 10, 1997April 30, 2027OSTENDORF, MARIreporter.nih.gov
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)NIHNational Institute on Aging2021 to 2025$65,403,220July 15, 2002May 31, 2027FOROUD, TATIANA M.reporter.nih.gov
Blood and Marrow Transplant Clinical Trials Network DCC- The Medical College of Wisconsin, Inc.NIHNational Heart, Lung, and Blood Institute2021 to 2025$36,418,175September 15, 2017August 31, 2031HAMADANI, MEHDI HUSSAINreporter.nih.gov
A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy ResearchNIHNational Cancer Institute2021 to 2025$30,268,190March 1, 1998February 29, 2028SHAW, BRONWENreporter.nih.gov
Allopregnanolone as Regenerative Therapeutic for Alzheimer's: Phase 2 Clinical TrialNIHNational Institute on Aging2021 to 2025$28,784,116August 15, 2019April 30, 2027BRINTON, ROBERTA EILEENreporter.nih.gov
RADX BLUEPRINT MEDTECH TRANSLATOR COHORT 2 - COMMERCIALIZATION CENTER - HEALNIHNational Heart, Lung, and Blood Institute2022 to 2025$27,543,152June 2, 2025June 1, 2026reporter.nih.gov
EO14042 DEVELOPMENT, STATISTICAL DESIGN, MONITORING AND COORDINATION OF VISION CLINICAL TRIALS AND EPIDEMIOLOGY RESEARCHNIHOffice of the Director, National Institutes of Health2022 to 2025$25,277,032November 1, 2021October 31, 2026MENEZES, SUPRIYAreporter.nih.gov
The Origins of Alzheimer Disease in African AmericansNIHNational Institute on Aging2022 to 2025$20,889,453September 15, 2022June 30, 2027PERICAK-VANCE, MARGARET A.reporter.nih.gov
SCREENING OF INVESTIGATIONAL THERAPEUTICS TO TREAT, MODIFY OR PREVENT EPILEPSY FOR THE NINDS EPILEPSY THERAPY SCREENING PROGRAM (ETSP)NIHNational Institute on Drug Abuse2022 to 2025$20,858,598March 23, 2022December 31, 2025WILCOX, KARENreporter.nih.gov
Replication Study of Off-Target Assays for Guide RNAs in CRISPR-Based TherapeuticsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$17,077,732December 1, 2024April 30, 2025SAHA, KRISHANUreporter.nih.gov
Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementiasNIHNational Institute on Aging2021 to 2025$15,514,157September 30, 2021May 31, 2027ELLERBY, LISA Mreporter.nih.gov
Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategiesNIHNational Institute on Aging2022 to 2025$14,689,794September 15, 2019December 31, 2026PERLS, THOMAS Treporter.nih.gov
Personalized Modeling of CAR-T Cell Immunotherapy Using iPSC-Derived Effectors and Patient- Derived Tumor OrganoidsNIHNational Cancer Institute2023 to 2025$12,675,268March 1, 1997August 31, 2026LIBUTTI, STEVEN K.reporter.nih.gov
Advancing brain health research through male germline editing in marmosetsNIHNational Institute on Drug Abuse2021 to 2025$12,061,296August 1, 2021May 31, 2027HERMANN, BRIAN PETERreporter.nih.gov
Center for Live Cell GenomicsNIHNational Human Genome Research Institute2021 to 2025$11,992,289September 15, 2021June 30, 2027HAUSSLER, DAVID Hreporter.nih.gov
Supplement to TR01 Human cortical development and neural plasticity altered by trisomy 21NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$11,380,369September 10, 2021August 31, 2027BHATTACHARYYA, ANITAreporter.nih.gov
Revealing the single cell determinants of brain relevant to persistent HIV infection and opioid use disorderNIHNational Institute on Drug Abuse2021 to 2025$11,197,081September 30, 2021July 31, 2027RANA, TARIQ Mreporter.nih.gov
Site-Directed RNA Editing of Nav1.7 as a Novel AnalgesicNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$11,194,636September 23, 2021August 31, 2027ROSENTHAL, JOSHUA J.C.reporter.nih.gov
Scientific Management and Support to the National Institute of Mental Health (NIMH) Repository and Genomics Resource (NRGR)NIHNational Institute on Drug Abuse2025$10,685,838August 11, 2025August 10, 2026reporter.nih.gov
Determining the mechanism of pks+ E.coli-associated carcinogenesis in early onset colorectal cancer.NIHNational Cancer Institute2022 to 2025$9,558,240September 20, 2022August 31, 2027O'REILLY, EILEEN MARYreporter.nih.gov
Uncovering the Genetic Mechanisms of the Chromosome 17q21.31 Tau Haplotype on Neurodegeneration Risk in FTD and PSPNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,418,230September 1, 2021August 31, 2026GOATE, ALISON Mreporter.nih.gov
Identification of TDP-43 Modifiers Through Single-Cell Transcriptional and Epigenomic Dissection of ALS and FTLD-MNDNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$9,106,321September 29, 2021August 31, 2026DONNELLY, CHRISTOPHER JAMESreporter.nih.gov
High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular PhenotypesNIHNational Human Genome Research Institute2021 to 2025$8,874,835September 1, 2021May 31, 2027GERSBACH, CHARLES A.reporter.nih.gov
Multiscale functional characterization of genomic variation in human developmental disordersNIHNational Human Genome Research Institute2021 to 2025$8,736,987September 1, 2021May 31, 2027HON, GARY CHUNGreporter.nih.gov
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular InteractionsNIHNational Institute on Aging2021 to 2025$8,654,669July 1, 2021June 30, 2027TEMPLE, SALLYreporter.nih.gov
Alzheimer variants: Propagation of shared functional changes across cellular networksNIHNational Institute on Aging2021 to 2025$8,542,236July 15, 2021June 30, 2027DE JAGER, PHILIP Lreporter.nih.gov
Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis PathobiologyNIHNational Institute of General Medical Sciences2021 to 2025$8,479,606May 1, 2021April 30, 2027EFRON, PHILIP Areporter.nih.gov
Massively parallel characterization of variants and elements impacting transcriptional regulation in dynamic cellular systemsNIHNational Human Genome Research Institute2021 to 2025$8,077,896September 1, 2021May 31, 2027SHENDURE, JAY ASHOKreporter.nih.gov
Beyond GWAS: High Throughput Functional Genomics & Epigenome Editing to Elucidate the Effects of Genetic Associations for SchizophreniaNIHNational Institute of Mental Health2021 to 2025$8,050,699April 1, 2021January 31, 2027CRAWFORD, GREGORY Ereporter.nih.gov
Higher Order Chromatin and Genetic Risk for Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$7,828,464September 1, 2015May 31, 2027ROUSSOS, PANAGIOTISreporter.nih.gov
Restoring Vision with High-Fidelity Nonsense Codon CorrectionNIHNational Eye Institute2021 to 2025$7,812,597February 1, 2021November 30, 2026PATTNAIK, BIKASH RANJANreporter.nih.gov
Reexamining the Role of Dendrites in Neuronal FunctionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$7,740,604August 1, 2023July 31, 2028YUSTE, RAFAELreporter.nih.gov
JAX MorPhiC Data Production CenterNIHNational Human Genome Research Institute2022 to 2025$7,698,185August 4, 2022May 31, 2027ROBSON, PAULreporter.nih.gov
Early Phase Clinical Cancer Prevention ConsortiumNIHNational Cancer Institute2021 to 2025$7,613,555July 7, 2020July 31, 2031SCHUETZE, SCOTT MICHAELreporter.nih.gov
Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primatesNIHNational Institute on Drug Abuse2023 to 2025$7,434,979June 1, 2023February 29, 2028RANA, TARIQ Mreporter.nih.gov
Application of Progenitor Niche Signals to Ex Vivo NephrogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,389,413September 15, 2021June 30, 2027OXBURGH, LEIFreporter.nih.gov
Therapeutics targeting TDP-43 to treat Alzheimer's disease and related disordersNIHNational Institute on Aging2021 to 2025$7,375,647July 1, 2021December 31, 2026REITZ, ALLEN BERNARDreporter.nih.gov
Center for scalable knockout and multimodal phenotyping in genetically diverse human genomesNIHNational Human Genome Research Institute2022 to 2025$7,316,442August 15, 2022May 31, 2027HUANGFU, DANWEIreporter.nih.gov
TRANSPIRE: A Prospective Cohort Study of Lung Injury After Hematopoietic Stem Cell Transplant in Children.NIHNational Heart, Lung, and Blood Institute2021 to 2025$7,251,380September 1, 2021May 31, 2027DAVIES, STELLA MARGARETreporter.nih.gov
Identification and Characterization of Cell-Specific Transposable Elements Implicated on Alzheimer Disease and Healthy AgingNIHNational Institute on Aging2022 to 2025$7,239,829August 15, 2022June 30, 2027CRUCHAGA, CARLOSreporter.nih.gov
Elucidating single cell changes in neurogenic brain regions during HIV and cannabinoid exposureNIHNational Institute on Drug Abuse2023 to 2025$7,084,951May 15, 2023March 31, 2028NDHLOVU, LISHOMWA Creporter.nih.gov
Genomic control of gene regulatory networks governing early human lineage decisionsNIHNational Human Genome Research Institute2021 to 2025$7,036,239August 19, 2021May 31, 2026HUANGFU, DANWEIreporter.nih.gov
Overcoming Barriers to retinal ganglion cell replacement in experimental glaucomaNIHNational Eye Institute2021 to 2025$7,031,142September 30, 2021July 31, 2027MEYER, JASON STEPHENreporter.nih.gov
Primary Open Angle African-American Glaucoma Genetics Study RenewalNIHNational Eye Institute2021 to 2025$6,924,827April 1, 2014March 31, 2026O'BRIEN, JOAN Mreporter.nih.gov
Functional genomic studies in diverse populations to characterize risk loci for Alzheimer DiseaseNIHNational Institute on Aging2021 to 2025$6,908,458July 15, 2021June 30, 2027VANCE, JEFFERY MARVINreporter.nih.gov
The NINDS Human Cell and Data Repository (U24 renewal)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,898,547September 30, 2015July 31, 2030KNOWLES, JAMES Areporter.nih.gov
Precision Editing of Granulin Mutations that Cause Frontotemporal DementiaNIHNational Institute of Neurological Disorders and Stroke2025$6,580,415August 15, 2025July 31, 2029SONTHEIMER, ERIK J.reporter.nih.gov
Spatial multiomic mapping of gene function with CRISPRoffNIHNational Human Genome Research Institute2022 to 2025$6,562,020September 1, 2022June 30, 2027GILBERT, LUKEreporter.nih.gov
Molecular and cellular characterization of essential human genes.NIHNational Human Genome Research Institute2022 to 2025$6,526,413September 22, 2022June 30, 2027ADLI, MAZHARreporter.nih.gov
The effects of Alzheimer's disease risk genes on metabolism and signaling across cell typesNIHNational Institute on Aging2022 to 2025$6,477,664September 19, 2022August 31, 2027FRAENKEL, ERNESTreporter.nih.gov
The impact of genomic variation on environment-induced changes in pancreatic beta cell statesNIHNational Human Genome Research Institute2021 to 2025$6,348,795September 7, 2021May 31, 2027CARTER, HANNAH KATHRYNreporter.nih.gov
Molecular Mechanisms of Pathogenesis in Huntington’s diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,238,150May 1, 2020April 30, 2028THOMPSON, LESLIE MICHELSreporter.nih.gov
Design of Precision Small Molecules Targeting RNA Repeating Transcripts to Manipulate and Study Disease BiologyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,233,749May 1, 2020April 30, 2028DISNEY, MATTHEW Dreporter.nih.gov
Elucidate the roles of Alzheimer's disease risk genes and variants in gene expression and AD-related phenotypesNIHNational Institute on Aging2022 to 2025$6,109,739September 15, 2022August 31, 2027SHEN, YINreporter.nih.gov
Leveraging genetic variation to dissect gene regulatory networks of reprogramming to pluripotencyNIHNational Human Genome Research Institute2021 to 2025$6,016,057September 1, 2021May 31, 2027LUO, CHONGYUANreporter.nih.gov
Defining causal roles of genomic variants on gene regulatory networks with spatiotemporally-resolved single-cell multiomicsNIHNational Human Genome Research Institute2021 to 2025$6,001,599September 1, 2021May 31, 2026WU, HAOreporter.nih.gov
Dissecting the role of sex-linked genes and APOE e4 risk in ADNIHNational Institute on Aging2021 to 2025$5,928,484September 30, 2021July 31, 2027YOUNG, JESSICA ELAINEreporter.nih.gov
Chaperome networks in Alzheimer's diseaseNIHNational Institute on Aging2021 to 2025$5,927,093February 15, 2021January 31, 2027CHIOSIS, GABRIELAreporter.nih.gov
Multimodal histologic atlas of human bone marrowNIHNational Heart, Lung, and Blood Institute2022 to 2025$5,888,084August 1, 2022June 30, 2026BENDALL, SEAN CURTISreporter.nih.gov
Accelerating photoreceptor replacement therapy with in-vivo cellular imaging of retinal functionNIHNational Eye Institute2021 to 2025$5,733,511September 30, 2021January 31, 2027MCGREGOR, JULIETTE ELIZABETHreporter.nih.gov
Environmental Biosensors in the Oligodendrocyte LineageNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,732,603May 15, 2019April 30, 2027CASACCIA, PATRIZIAreporter.nih.gov
NPTX2: Preserving memory circuits in normative aging and Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$5,697,103May 1, 2021April 30, 2027BARNES, CAROL A.reporter.nih.gov
Mechanistic Analysis of Genetic Modifiers in Parkinson's DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,598,826May 1, 2021April 30, 2029KRAINC, DIMITRIreporter.nih.gov
The role of stem cells and the microenvironment in gastrointestinal cancersNIHNational Cancer Institute2021 to 2025$5,569,272January 7, 2016August 31, 2030WANG, TIMOTHY CRAGINreporter.nih.gov
Molecular Biology Across Scales Training ProgramNIHNational Institute of General Medical Sciences2023 to 2025$5,468,885July 1, 2023June 30, 2028BILDER, DAVIDreporter.nih.gov
Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimer’s DiseaseNIHNational Institute on Aging2021 to 2025$5,445,522September 30, 2021May 31, 2027KELLIS, MANOLISreporter.nih.gov
New mechanisms and technologies for understanding post-transcriptional gene regulation in neuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,391,456June 1, 2019May 31, 2027JAFFREY, SAMIE Rreporter.nih.gov
Mechanisms of neurodegenerative diseases: intersections with ubiquitin pathwaysNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,356,529May 1, 2021April 30, 2029PAULSON, HENRY Lreporter.nih.gov
Assay and Data Generation Center (ADGC) for the Model of iPSC-derived Neurons for NPD (MiNND)NIHNational Institute of Mental Health2023 to 2025$5,271,743May 17, 2023April 30, 2028PANG, ZHIPING P.reporter.nih.gov
Cell plasticity in the origin of gastric carcinogenesisNIHNational Cancer Institute2022 to 2025$5,262,457September 1, 2025August 31, 2027CHOI, EUNYOUNGreporter.nih.gov
Continuous Neurogenesis in the Mammalian HippocampusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,244,633May 1, 2020April 30, 2028SONG, HONGJUNreporter.nih.gov
Novel therapeutic development for small cell lung cancerNIHNational Cancer Institute2021 to 2025$5,214,420August 10, 2021July 31, 2028RUDIN, CHARLES M.reporter.nih.gov
The TGFβ Signaling Pathway in Development and CancerNIHNational Cancer Institute2021 to 2025$5,182,391September 1, 2020August 31, 2027MASSAGUE, JOANreporter.nih.gov
Cellular Decision MakingNIHNational Institute of General Medical Sciences2021 to 2025$5,164,037June 1, 2016May 31, 2026WEINER, ORION Dreporter.nih.gov
Fecal Microbiota Transplantation and Fiber for the Treatment of Graft-versus-host Disease After Hematopoietic Cell TransplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$5,128,451September 1, 2023June 30, 2027FREDRICKS, DAVID NEALreporter.nih.gov
Novel Strategies to Improve Blood Transfusion PracticeNIHNational Heart, Lung, and Blood Institute2024 to 2025$5,119,758August 15, 2022July 31, 2027LUO, HONGBO Rreporter.nih.gov
Targeting Dysregulated RNA Splicing in Neurodegenerative DiseasesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$5,093,143September 1, 2023August 31, 2028LAGIER-TOURENNE, CLOTILDEreporter.nih.gov
A Precision Medicine Approach for the Study of Targetable Pathways in Vascular DementiaNIHNational Institute on Aging2022 to 2025$5,086,657February 1, 2022November 30, 2026GOATE, ALISON Mreporter.nih.gov
Toward a Mechanism-Based Approach to Treating Cardiac ArrhythmiaNIHNational Heart, Lung, and Blood Institute2021 to 2025$5,079,600March 6, 2019February 28, 2026KNOLLMANN, BJORN Creporter.nih.gov
UCLA High-Throughput Neuropsychiatric Disorder Phenotyping Center (UCLA HT-NPC)NIHNational Institute of Mental Health2023 to 2025$5,035,081May 1, 2023April 30, 2028GESCHWIND, DANIEL Hreporter.nih.gov
Mucus-degrading intestinal bacteria and toxicities of hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2024 to 2025$5,032,505September 21, 2024July 31, 2029JENQ, ROBERTreporter.nih.gov
1/2A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation with Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients with Severe Aplastic AnemiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$5,023,972April 1, 2022March 31, 2029SHAW, BRONWENreporter.nih.gov
Novel vascular smooth muscle cell progenitors in development and diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,999,830July 1, 2020June 30, 2027GREIF, DANIELreporter.nih.gov
Multiethnic genomic epigenomic and transcriptomic fine-mapping and functional validation analysis of schizophrenia and bipolar disorder risk lociNIHNational Institute of Mental Health2021 to 2025$4,996,628January 1, 2021October 31, 2026ROUSSOS, PANAGIOTISreporter.nih.gov
Leveraging Natural Phenotypic Variations of Heterogenous ALS Populations-in-a-Dish to Enable Scalable Drug DiscoveryNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$4,949,698September 18, 2022August 31, 2027ICHIDA, JUSTIN KAWIKAreporter.nih.gov
Gastroesophageal junction stem cells as the origin of Barretts esophagus and cancerNIHNational Cancer Institute2022 to 2025$4,948,268September 1, 2025August 31, 2027WANG, TIMOTHY CRAGINreporter.nih.gov
Dose-response of aerobic training during total neoadjuvant therapy for locally advanced rectal cancerNIHNational Cancer Institute2022 to 2025$4,937,681May 6, 2022April 30, 2027SCOTT, JESSICAreporter.nih.gov
Experimental Cellular Approaches to Genotype × Environment InteractionNIHNational Institute of General Medical Sciences2023 to 2025$4,934,544September 7, 2023August 31, 2028CURRAN, JOANNE E.reporter.nih.gov
Modeling drugs of abuse-HIV interactions using iPSC-derived human cerebral organoidsNIHNational Institute on Drug Abuse2021 to 2025$4,890,555September 30, 2021July 31, 2026SANNA, PIETRO Preporter.nih.gov
Investigating the heterogeneity and coordination of hematopoietic stem cellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,840,269August 1, 2020July 31, 2027LU, RONGreporter.nih.gov
Regulation of chromatin dynamicsNIHNational Institute of General Medical Sciences2021 to 2025$4,836,313June 1, 2017May 31, 2027PETERSON, CRAIG Lreporter.nih.gov
Program to promote lung regeneration and block fibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,819,926February 15, 2020February 14, 2026CHAPMAN, HAROLD Areporter.nih.gov
Novel Stem Cell Immunotherapy for MDR-TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,800,190June 4, 2021May 31, 2026JAGANNATH, CHINNASWAMYreporter.nih.gov
Establishing patient-derived iPSCs as a platform for discovery research in NAFLDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$4,780,391June 1, 2023March 31, 2028MAHER, JACQUELYN J.reporter.nih.gov
Durable HIV Vaccine Targeting Mucosal EpitheliumNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,751,308August 1, 2022July 31, 2027GAUDUIN, MARIE-CLAIRE ELISABETHreporter.nih.gov
Defining mechanisms driving salivary gland regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$4,717,861September 18, 2018June 30, 2026KNOX, SARAH MONICAreporter.nih.gov
Defining and Controlling Airway DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,706,100March 8, 2019February 28, 2026HOLTZMAN, MICHAEL Jreporter.nih.gov
Development of Innovative Resources to Advance MDS ResearchNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$4,661,966September 15, 2023July 31, 2028BLEAKLEY, MARIEreporter.nih.gov
Heritable immunization of the white-footed mouse reservoir of Lyme diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,657,626September 1, 2021August 31, 2026ESVELT, KEVINreporter.nih.gov
Altering Cardiac Cell Fate for Heart RepairNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,621,749January 13, 2021November 30, 2027QIAN, LIreporter.nih.gov
Bcl-2 and Mcl-1 inhibition for induction of hematopoietic chimerism and renal allograft tolerance without myelosuppression in nonhuman primatesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,613,595June 3, 2022May 31, 2027KAWAI, TATSUOreporter.nih.gov
Early to Late Events in Colorectal Neoplasia: Basic Biology to Clinical ImplementationNIHNational Cancer Institute2021 to 2025$4,608,771April 1, 2017July 31, 2031COFFEY, ROBERT J.reporter.nih.gov
Molecular and Cellular Regulation of Pre-Leukemic Stem Cells and their Therapeutic TargetingNIHNational Cancer Institute2021 to 2025$4,594,192September 1, 2021August 31, 2028STEIDL, ULRICHreporter.nih.gov
Molecular Pathogenesis of Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2025$4,591,274August 13, 2015June 30, 2029LEY, TIMOTHY J.reporter.nih.gov
Cell signaling in development and regenerationNIHNational Institute of General Medical Sciences2021 to 2025$4,582,546May 6, 2016July 9, 2026JIANG, JINreporter.nih.gov
Mechanisms underlying gastric intestinal metaplasia and carcinogenesisNIHNational Cancer Institute2022 to 2025$4,560,310September 20, 2022August 31, 2027RUSTGI, ANIL Kreporter.nih.gov
Therapeutic Targeting of Human AML Stem CellsNIHNational Cancer Institute2021 to 2025$4,546,001September 8, 2020August 31, 2027JORDAN, CRAIG T.reporter.nih.gov
Pathological Mechanisms of Human Cerebellar MalformationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,519,501September 1, 2016June 30, 2028MILLEN, KATHLEEN JOYCEreporter.nih.gov
Mechanisms of Developmental MyelinationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,505,832May 15, 2021April 30, 2029APPEL, BRUCE Hreporter.nih.gov
Functional Analysis of Epigenetic ComplexesNIHNational Institute of General Medical Sciences2021 to 2025$4,411,981April 1, 2019February 28, 2029KINGSTON, ROBERTreporter.nih.gov
A nonhuman primate model of stem cell transplantation to understand determinants of post-transplant SIV clearanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,411,202December 21, 2016June 30, 2026SACHA, JONAH B.reporter.nih.gov
Cell-cell interactions governing lung epithelial progenitor cellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,407,300March 15, 2020January 31, 2027KIM, CARLA F.reporter.nih.gov
Regulation of proliferation and differentiation in the male germ line adult stem cell lineageNIHNational Institute of General Medical Sciences2021 to 2025$4,349,146June 1, 2020May 31, 2030FULLER, MARGARET Treporter.nih.gov
Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,345,357December 16, 2015May 31, 2028WU, JOSEPH C.reporter.nih.gov
The TET-DNMT-ASXL1-OGT axis: relevance to clonal hematopoiesis, heterochromatin integrity and cancerNIHNational Cancer Institute2021 to 2025$4,334,400September 1, 2016August 31, 2031RAO, ANJANAreporter.nih.gov
Mechanism of Epigenetic InheritanceNIHNational Institute of General Medical Sciences2021 to 2025$4,320,227September 1, 2016July 31, 2026ZHANG, ZHIGUOreporter.nih.gov
Impact of Infection and Inflammation on Primitive HematopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,290,831July 1, 2021June 30, 2028KING, KATHERINE YUDEHreporter.nih.gov
Charting human islet maturation via combined soft nanoelectronics and single-cell spatial transcriptomicsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$4,276,659September 17, 2021May 31, 2027LIU, JIAreporter.nih.gov
Data science approaches to autism: environmental modulators of the transcriptome and gene-x-environment interactionsNIHOffice of the Director, National Institutes of Health2025$4,255,873September 29, 2025September 28, 2028GESCHWIND, DANIEL Hreporter.nih.gov
Microglia contribution to disease pathogenesis in C9orf72 ALS/FTDNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,229,195September 1, 2021August 31, 2027SATTLER, RITAreporter.nih.gov
Molecular Regulation of Progressive Pulmonary FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,220,741March 1, 2020February 28, 2027NOBLE, PAUL WESLEYreporter.nih.gov
Pathogenic Mechanisms in Christianson Syndrome and NHE6-Related DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,197,634September 15, 2019June 30, 2029MORROW, ERIC Mreporter.nih.gov
MSC Exosome Treatment for BPD: Impact on Immunity and Lung DevelopmentNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,182,213March 1, 2019February 28, 2027KOUREMBANAS, STELLAreporter.nih.gov
High-throughput in vivo and in vitro functional and multi-omics screens of neuropsychiatric and neurodevelopmental disorder risk genesNIHNational Institute of Mental Health2023 to 2025$4,152,990May 1, 2023April 30, 2028HOFFMAN, ELLEN Jreporter.nih.gov
Biospecimen procurement and tissue microarray manufacture for the CHTNNIHNational Cancer Institute2021 to 2025$4,152,759April 1, 2019March 31, 2029MOSKALUK, CHRISTOPHER A.reporter.nih.gov
Understanding the role of metabolism in cancerNIHNational Cancer Institute2021 to 2025$4,148,510September 10, 2019August 31, 2026VANDER HEIDEN, MATTHEW G.reporter.nih.gov
Resolving complex alternative splicing of psychiatric disease genes using single-cell approachesNIHNational Institute of Mental Health2021 to 2025$4,123,629August 5, 2021May 31, 2026FANG, GANGreporter.nih.gov
Functional convergence following disruption of diverse genes associated with neurodevelopmental disordersNIHNational Institute of Mental Health2021 to 2025$4,120,229May 20, 2021March 31, 2027BRENNAND, KRISTEN JENNIFERreporter.nih.gov
Understanding the functional impacts of Aβ variants in Alzheimer's disease with human brain organoidsNIHNational Institute on Aging2022 to 2025$4,119,330August 1, 2022July 31, 2027WEN, ZHEXINGreporter.nih.gov
Neuronal ApoE Drives Selective Neurodegeneration in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$4,070,240August 1, 2021May 31, 2026HUANG, YADONGreporter.nih.gov
Clinical and genetic risk factors associated with adverse long-term health outcomes after curative therapies in individuals with sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,065,243March 15, 2021February 28, 2027DEBAUN, MICHAEL R.reporter.nih.gov
Nuclear pore complex quality control in ALS/FTDNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,005,112May 1, 2021April 30, 2026ROTHSTEIN, JEFFREY Dreporter.nih.gov
Base editing and prime editing for sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,000,055January 1, 2021June 30, 2030WEISS, MITCHELL Jreporter.nih.gov
Impact of chronic alcohol consumption on the functional and epigenetic landscapes of monocytes and their progenitorsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,998,523September 1, 2020August 31, 2029MESSAOUDI, ILHEMreporter.nih.gov
Regulation of mRNA processing: Mechanisms and ConsequencesNIHNational Institute of General Medical Sciences2021 to 2025$3,993,090June 8, 2016May 31, 2026MANLEY, JAMES L.reporter.nih.gov
Combining Targeted RIT and Synergistic Novel Agent-RenewalNIHNational Cancer Institute2021 to 2025$3,984,924June 1, 2020May 31, 2027OROZCO, JOHNNIE JOSEreporter.nih.gov
Engineered Stem Cells for Cardiac RepairNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,984,462February 1, 2018March 31, 2027REGNIER, MICHAELreporter.nih.gov
Drug repositioning for Alzheimer's disease via genetics, electronic health records, and human iPSC modelsNIHNational Institute on Aging2021 to 2025$3,970,571April 15, 2021December 31, 2026LI, BINGSHANreporter.nih.gov
Interrogating Complex Methylome Network with Integrated Chemical Biology ToolsNIHNational Institute of General Medical Sciences2021 to 2025$3,968,800June 1, 2019May 31, 2029LUO, MINKUIreporter.nih.gov
Mesenchymal Vascular Progenitor Depletion Promotes Lung Aging and Susceptibility to EmphysemaNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,964,079January 1, 2022December 31, 2028MAJKA, SUSAN Mreporter.nih.gov
Coronal Suture Development in Health and DiseaseNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,959,879September 20, 2021July 31, 2027HOLMES, GREG PETERreporter.nih.gov
Hematopoietic stem and progenitor cell regulation for enhanced clinical efficacyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,911,609August 1, 2015July 31, 2028KAPUR, REUBENreporter.nih.gov
Impaired activity-dependent protein synthesis in dendrites and pathophysiology in tauopathyNIHNational Institute on Aging2021 to 2025$3,904,840August 1, 2021July 31, 2027TRACY, TARAreporter.nih.gov
Osteoarthritis Progression And Sensory Pathway AlterationsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,899,677May 1, 2013July 31, 2029MALFAIT, ANNE-MARIEreporter.nih.gov
Multifunctional morphogens: patterning precision and mesoderm migrationNIHNational Institute of General Medical Sciences2021 to 2025$3,886,095July 1, 2020August 31, 2029HEEMSKERK, IDSE JOANNESreporter.nih.gov
Generation of a temporal, spatial, and molecular map of in situ hematopoiesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,870,336September 15, 2022May 31, 2027CAMARGO, FERNANDOreporter.nih.gov
Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated CardiomyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,869,226May 1, 2018May 31, 2027WU, JOSEPH C.reporter.nih.gov
T cells in the aging brainNIHNational Institute on Aging2021 to 2025$3,850,998June 15, 2021March 31, 2027BRUNET, ANNEreporter.nih.gov
Understanding Skin Tissue Repair in Live MammalsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,829,886March 1, 2018August 31, 2027GRECO, VALENTINAreporter.nih.gov
The role of hypoxia in venous neointimal hyperplasia in hemodialysis graftsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,815,411February 1, 2010April 30, 2028MISRA, SANJAYreporter.nih.gov
Gaining insight into psychiatric disease by engineering piece by piece the human brain in vitroNIHNational Institute of Mental Health2025$3,812,108August 1, 2015August 19, 2029PASCA, SERGIUreporter.nih.gov
Harnessing Glycoproteomics and Glycomics to Understand Cardiac Biology and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,810,605February 1, 2021January 31, 2028GUNDRY, REBEKAH L.reporter.nih.gov
TDP-43 acetylation, phase separation, aggregation, and clearance by antibody-mediated degradationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,806,187April 1, 2021March 31, 2026CLEVELAND, DON Wreporter.nih.gov
Cell competition in pulmonary fibrosis and ARDSNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,796,920August 20, 2022July 31, 2029DE LANGHE, STIJN PIET JOHANreporter.nih.gov
Develop AD Connectivity Maps with Human iPSC-Derived Brain Cells and their UseNIHNational Institute on Aging2022 to 2025$3,748,222September 1, 2022May 31, 2027HUANG, YADONGreporter.nih.gov
Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse BrainNIHNational Institute on Drug Abuse2021 to 2025$3,747,870August 1, 2021May 31, 2027AKBARIAN, SCHAHRAMreporter.nih.gov
Genomic and functional characterization of ASD and ID-associated MYT1L mutationNIHNational Institute of Mental Health2021 to 2025$3,747,342December 1, 2020October 31, 2026KROLL, KRISTEN Lreporter.nih.gov
Ikaros regulation: study on hemo-lymphopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,733,682September 5, 2011March 31, 2029GEORGOPOULOS, KATIAreporter.nih.gov
Cilia in Heart Development and DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,728,670February 15, 2019January 31, 2026BRUECKNER, MARTINAreporter.nih.gov
Cardiogenesis: Molecular MechanismsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,717,603January 10, 1997May 31, 2028SRIVASTAVA, DEEPAKreporter.nih.gov
Live Imaging of Skin RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,713,235September 7, 2012August 31, 2027GRECO, VALENTINAreporter.nih.gov
"Corral and Kill" strategy for HIV eradication using MSC in an SIV modelNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,712,736March 23, 2020February 28, 2030DANDEKAR, SATYAreporter.nih.gov
Novel therapeutic gene editing to induce fetal hemoglobin for sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,710,340September 1, 2023August 31, 2028WEISS, MITCHELL Jreporter.nih.gov
Epigenetic gene regulation in the germlineNIHNational Institute of General Medical Sciences2021 to 2025$3,700,633July 5, 2021December 31, 2026NAMEKAWA, SATOSHIreporter.nih.gov
Systematic Functional Interpretation of Regulatory Variants in Neuropsychiatric DisordersNIHNational Institute of Mental Health2021 to 2025$3,689,169May 4, 2016January 31, 2027DUAN, JUBAOreporter.nih.gov
Optimizing Hematopoietic Stem Cell Transplantation For The Treatment Of Hematological MalignanciesNIHNational Cancer Institute2021 to 2025$3,687,540September 7, 2017June 30, 2032DIPERSIO, JOHN F.reporter.nih.gov
The role of ABI3 in Alzheimers diseaseNIHNational Institute on Aging2021 to 2025$3,667,316September 30, 2021May 31, 2027KIM, JUNGSUreporter.nih.gov
Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTDNIHNational Institute on Aging2021 to 2025$3,657,244March 1, 2021November 30, 2026KELLIS, MANOLISreporter.nih.gov
Neurotoxic and neurodegenerative risks from chronic exposure to metal mixtures in e-cigarette aerosolNIHNational Institute of Environmental Health Sciences2021 to 2025$3,656,277September 8, 2021June 30, 2027RE, DIANE BERENGEREreporter.nih.gov
Effects of inflammaging on intestinal epithelial cells and aspirin chemoprevention.NIHNational Cancer Institute2021 to 2025$3,654,173April 5, 2021March 31, 2027CHAN, ANDREW Treporter.nih.gov
Emulating Immune Dysregulation by Trisomy 21 in a Multi-Organ-on-a-Chip SystemNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,649,414September 20, 2021July 31, 2026HAJIPOURAN BENAM, KAMBEZreporter.nih.gov
Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHDNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,648,726August 15, 2015May 31, 2026SARANTOPOULOS, STEFANIEreporter.nih.gov
Nuclear and Glial Dysfunction in NeurodegenerationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,647,532May 16, 2023April 30, 2031ROTHSTEIN, JEFFREY Dreporter.nih.gov
Defining gene regulatory networks driving cortical evolution and brain developmentNIHNational Institute of Mental Health2021 to 2025$3,647,249July 1, 2021April 30, 2027DE LA TORRE-UBIETA, LUISreporter.nih.gov
FunGen-xQTL: Unraveling the genetic basis of molecular functions in Alzheimer's DiseaseNIHNational Institute on Aging2025$3,642,232August 5, 2025July 31, 2030WANG, GAOreporter.nih.gov
Molecular strategies for early detection and targeting of cancerNIHNational Cancer Institute2022 to 2025$3,640,759August 12, 2015July 31, 2028REYA, TANNISHTHAreporter.nih.gov
Systems genetics analysis of tumor evolution in the mouseNIHNational Cancer Institute2021 to 2025$3,631,667June 1, 2017July 31, 2032BALMAIN, ALLANreporter.nih.gov
Immunovascular interactions in postoperative delirium superimposed on dementia (DSD).NIHNational Institute on Aging2022 to 2025$3,624,866September 15, 2022August 31, 2027TERRANDO, NICCOLOreporter.nih.gov
Latrophilin Function in Synapse FormationNIHNational Institute of Mental Health2021 to 2025$3,624,291July 1, 2021April 30, 2026SUDHOF, THOMAS C.reporter.nih.gov
Intranasal Treatment of Stem Cell-derived Extracellular Vesicles for Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$3,620,000August 1, 2022July 31, 2027SHETTY, ASHOK Kreporter.nih.gov
Targeting the NLRP3 Inflammasome to Mitigate Neuroinflammation and HIV Persistence in the CNS: Mechanisms and Therapeutic StrategiesNIHNational Institute of Mental Health2025$3,613,504September 22, 2025September 21, 2029SWARTZ, TALIA Hreporter.nih.gov
HCMV-induced innate-like CD8 T cells and allogeneic HCT outcomeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,601,018April 9, 2021March 31, 2027HSU, KATHARINE Creporter.nih.gov
New technologies to identify molecular regulators of the human hippocampus neurogenic niche in healthy aging and Alzheimer's DiseaseNIHNational Institute on Aging2022 to 2025$3,598,243May 15, 2022February 28, 2027DUPONT, MAURA BOLDRINIreporter.nih.gov
Origin of Cortical Species-specific DistinctionsNIHNational Institute on Drug Abuse2021 to 2025$3,571,176April 1, 2025March 31, 2030RAKIC, PASKOreporter.nih.gov
Predicting and Preventing Chemotherapy-Induced Cardiotoxicity in African American ChildrenNIHNational Cancer Institute2021 to 2025$3,570,931August 5, 2021July 31, 2026BURRIDGE, PAUL W.reporter.nih.gov
Human iPSC Model to Elucidate Metabolic Interplay in Diabetic CardimyopathyNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,569,593April 1, 2019April 30, 2027WU, JOSEPH C.reporter.nih.gov
DNA transposons and alternative pre-mRNA splicing.NIHNational Institute of General Medical Sciences2021 to 2025$3,562,349June 15, 2016May 31, 2027RIO, DONALD Creporter.nih.gov
Probing cytosolic nucleic acid sensing pathways in cancerNIHNational Cancer Institute2021 to 2025$3,548,978January 1, 2021December 31, 2026LAUGHNEY, ASHLEY MARIEreporter.nih.gov
Reprogramming of mature SMCs to vascular progenitor cells: Focus on Vascular FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,548,396January 18, 2019June 30, 2027WEISER-EVANS, MARY CMreporter.nih.gov
Preventing GVHD by inhibition of alloantigen presentation in the gutNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,543,040July 1, 2019June 30, 2027HILL, GEOFFREY ROGERreporter.nih.gov
Ocular Immune Regulation by Mesenchymal Stem CellsNIHNational Eye Institute2021 to 2025$3,542,949April 1, 2015September 14, 2028CHAUHAN, SUNIL Kreporter.nih.gov
Endogenous barcoding to determine complex dynamics of adult neurogenesis in aging and Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$3,540,268July 1, 2022March 31, 2027ENIKOLOPOV, GRIGORI Nreporter.nih.gov
Inter- and Intra-cellular effects of cannabinoids, HIV and ART in the CNSNIHNational Institute on Drug Abuse2021 to 2025$3,529,874August 1, 2020May 31, 2027JORDAN-SCIUTTO, KELLY Lreporter.nih.gov
Discovery and CRISPR validation of genetic factors associated with antipsychotic-induced weight gain and cardiometabolic riskNIHNational Institute of Mental Health2021 to 2025$3,528,182February 12, 2021December 31, 2026NICOL, GINGER Ereporter.nih.gov
JAK-STAT Inhibition to Reduce Racial Disparities in Kidney DiseaseNIHNational Institute on Minority Health and Health Disparities2021 to 2025$3,524,489September 20, 2021May 31, 2027OLABISI, OPEYEMI AYODEJIreporter.nih.gov
Impact of the Human Herpesvirus 6A (HHV6A) latency gene U94A on Alzheimer disease pathologyNIHNational Institute on Aging2021 to 2025$3,507,363September 30, 2021May 31, 2026MAYER-PROSCHEL, MARGOTreporter.nih.gov
Craniofacial Morphogenesis in Prenatal Alcohol ExposureNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,497,846July 1, 1996August 31, 2029SMITH, SUSAN M.reporter.nih.gov
A Long Noncoding RNA Amerliorates Periodontitis via Distinct Epigenetic PathwaysNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,494,925December 1, 2020November 30, 2026CHEN, JAKE JINKUNreporter.nih.gov
Biochemical and cellular mechanisms linking actin mutations to visceral myopathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,487,348September 28, 2021August 31, 2027HEUCKEROTH, ROBERT Oreporter.nih.gov
Identifying Relapse Predictors and Therapeutic Vulnerabilities in Ph+ and Ph-like Acute Lymphoblastic LeukemiaNIHNational Cancer Institute2025$3,480,276August 1, 2025July 31, 2029LOH, MIGNON LEE-CHEUNreporter.nih.gov
Combination Adjuvants to Program Durable Immunity to Respiratory Viral and Fungal PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,479,164February 17, 2016April 30, 2027SURESH, MARULASIDDAPPAreporter.nih.gov
Probing Heterogeneity of Alzheimer's Disease Using iPSCsNIHNational Institute on Aging2021 to 2025$3,479,050July 15, 2018April 30, 2028YOUNG-PEARSE, TRACY Lreporter.nih.gov
Resolving the function of progranulin in lysosomal lipid metabolism and the etiology of Alzheimer's disease and frontotemporal dementiaNIHNational Institute on Aging2022 to 2025$3,471,933September 1, 2022August 31, 2027KUKAR, THOMAS Lreporter.nih.gov
Intensive tailored exercise training with NAD+ precursor supplementation to improve muscle mass and fitness in adolescent and young adult survivors of hematopoietic stem cell transplantationNIHNational Cancer Institute2021 to 2025$3,469,202September 1, 2021August 31, 2027MOSTOUFI-MOAB, SOGOLreporter.nih.gov
Defining mechanisms of disease and repair in a viral model of multiple sclerosisNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$3,467,101May 1, 2020April 30, 2029LANE, THOMAS Ereporter.nih.gov
Randomized trial of viral specific T-cell infusion to prevent viral infection after hematopoietic stem cell transplant.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,457,708July 1, 2021April 30, 2027DAVIES, STELLA MARGARETreporter.nih.gov
Cell Identity Determination in Human Brain: Somatic Mutation and Cell LineageNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,434,150December 16, 1994June 30, 2030WALSH, CHRISTOPHER A.reporter.nih.gov
Preserving physical function in patients with kidney diseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,428,324August 3, 2021June 30, 2026ABRAMOWITZ, MATTHEW Kreporter.nih.gov
Chemical tools for developmental biologyNIHNational Institute of General Medical Sciences2021 to 2025$3,426,216April 1, 2018June 30, 2028CHEN, JAMES Kreporter.nih.gov
Unraveling yellow fever 17D vaccine attenuation: The role of type I interferon and innate immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,421,854February 15, 2016July 31, 2027RICE, CHARLES Mreporter.nih.gov
The Impact of the Bone Marrow Niche's Immune Privilege on Psoriatic ArthritisNIHNational Institute of Allergy and Infectious Diseases2025$3,406,145August 8, 2025July 31, 2029FUJISAKI, JOJIreporter.nih.gov
Remediating fibrosis for salivary gland regenerationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,392,837April 1, 2019March 31, 2029LARSEN, MELINDAreporter.nih.gov
Modeling functional genomics of susceptibility to the persistent effects of environmental toxins in an elderly rural Indiana neurodegenerative cohortNIHNational Institute on Aging2022 to 2025$3,385,412September 15, 2022May 31, 2027BOWMAN, AARON Breporter.nih.gov
Developmental origins and homeostatic mechanisms underlying adult phenotypesNIHNational Institute of General Medical Sciences2021 to 2025$3,384,344May 1, 2017April 30, 2027PARICHY, DAVID Mreporter.nih.gov
Gene therapy for SCID-X1 with low dose busulfan and a SIN-lentiviral vectorNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,369,470July 7, 2016December 31, 2029WILLIAMS, DAVID Areporter.nih.gov
Nanoscale probes for sensing molecular functions in live cellsNIHNational Institute of General Medical Sciences2021 to 2025$3,364,334June 1, 2021May 31, 2027CUI, BIANXIAOreporter.nih.gov
Regulation of Hemoglobin SwitchingNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,354,270August 5, 2013January 31, 2027BLOBEL, GERD Areporter.nih.gov
Cellular and molecular mechanisms underlying DDX3X syndromeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,350,844January 1, 2021November 30, 2026SILVER, DEBRA L.reporter.nih.gov
Dystrophin ReplacementNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,349,499April 1, 1991April 30, 2026CHAMBERLAIN, JEFFREY Sreporter.nih.gov
Unraveling the molecular pathology of retinal degeneration through single cell genomicsNIHNational Eye Institute2021 to 2025$3,347,817June 1, 2021May 31, 2027AYYAGARI, RADHAreporter.nih.gov
Elucidating Anthracycline-Induced Cell Type-Specific Cardiovascular Toxicity with CRISPRi/a ScreensNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,345,164September 1, 2025August 31, 2030WU, JOSEPH C.reporter.nih.gov
Role of Energy Metabolism in Patterning the Vertebrate Musculo-Skeletal AxisNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,337,554March 1, 2016March 31, 2026POURQUIE, OLIVIERreporter.nih.gov
Regulation of Progenitor Cell Plasticity in Lung Development and Disease-RepairNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,331,553July 1, 2023June 30, 2030CARDOSO, WELLINGTON V.reporter.nih.gov
Why do Down Syndrome patients have high risk of Hirschsprung disease?NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,330,453September 15, 2022July 31, 2027CHAKRAVARTI, ARAVINDAreporter.nih.gov
Engineering synthetic immune cells with modular sentinel and therapeutic functions for T1DNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,328,254April 1, 2022September 30, 2026LIM, WENDELL Areporter.nih.gov
Modeling Tyrosine Kinase Inhibitor-Induced Vascular Dysfunction Using Human iPSCsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,324,533August 1, 2018June 30, 2027WU, JOSEPH C.reporter.nih.gov
Investigating aberrant vesicular degradation and lipid metabolism in neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2025$3,323,710August 15, 2025July 31, 2029BOSCO, DARYL ANGELAreporter.nih.gov
The Primate Corticospinal Connectome and TranscriptomeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,321,910September 15, 2017May 31, 2026TUSZYNSKI, MARK H.reporter.nih.gov
Leveraging 3D bioprinted organoid constructs to pattern and model human brain developmentNIHNational Institute of Mental Health2021 to 2025$3,321,612April 1, 2021January 31, 2026SLOAN, STEVEN Areporter.nih.gov
Novel Mechanisms of Exercise Training Effects on Glucose HomeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,320,917April 10, 2014December 31, 2028GOODYEAR, LAURIE Jreporter.nih.gov
Immunobiology of the normal and injured lungNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,312,758January 1, 2022December 31, 2028LOONEY, MARK ROBERTSreporter.nih.gov
Versatile, exponentially scalable methods for single cell molecular profilingNIHNational Human Genome Research Institute2021 to 2025$3,289,666September 15, 2019April 30, 2028SHENDURE, JAY ASHOKreporter.nih.gov
Proteogenetics of Autism Spectrum DisordersNIHNational Institute of Mental Health2021 to 2025$3,288,305August 1, 2013June 30, 2027YATES III, JOHN Rreporter.nih.gov
Extracellular Vesicle treatment and age-related neuropathology in non-human primatesNIHNational Institute on Aging2025$3,284,677September 15, 2020August 31, 2029MOORE, TARA Lreporter.nih.gov
Decoding innate immune signaling in normal and myelodysplastic hematopoiesisNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,283,833January 1, 2023December 31, 2029STARCZYNOWSKI, DANIELreporter.nih.gov
The Role of Secondary Bile Acids in Gastro-Esophageal NeoplasiaNIHNational Cancer Institute2022 to 2025$3,273,998September 1, 2022August 31, 2027ABRAMS, JULIANreporter.nih.gov
Development of novel genomic approaches for profiling cellular temporal-spatial dynamics of neurogenesis in Aging and Alzheimer's diseaseNIHNational Institute on Aging2022 to 2025$3,270,531June 1, 2022February 28, 2027CAO, JUNYUEreporter.nih.gov
Histone lactylation pathway in hair cycle: deacylases and their protein targetsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,263,621July 1, 2021April 30, 2026ZHAO, YINGMINGreporter.nih.gov
Mechanisms of Beta Cell FailureNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,260,500July 1, 2003July 31, 2026ACCILI, DOMENICOreporter.nih.gov
Identification of enteric Juvenile Protective Factors and their role in stimulating neurogenesis in the adult and ageing Enteric Nervous SystemNIHNational Institute on Aging2021 to 2025$3,254,354January 15, 2021December 31, 2026GOFF, LOYAL ANDREWreporter.nih.gov
Genetic Studies of Cortex Structure and DevelopmentNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,251,011September 30, 2016June 30, 2026RUBENSTEIN, JOHN L. R.reporter.nih.gov
A spatial view of hematopoietic regeneration dynamics in the bone marrowNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$3,245,428September 15, 2024July 31, 2029LU, RONGreporter.nih.gov
Design, prediction, and prioritization of systematic perturbations of the human genomeNIHNational Human Genome Research Institute2021 to 2025$3,243,707September 1, 2021May 31, 2027ALLEN, ANDREW Sreporter.nih.gov
Genetically Programmed Pancreatic Organoids with Self-Adaptive Multi-Lineage Population ControlNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,243,464September 1, 2021August 31, 2026WEISS, RONreporter.nih.gov
TREM2 Genotype-Informed Drug Repurposing and Combination Therapy Design for Alzheimer’s DiseaseNIHNational Institute on Aging2022 to 2025$3,240,062July 15, 2022March 31, 2027CHENG, FEIXIONGreporter.nih.gov
Multi-Targeting Oligonucleotide Therapeutics for Familial and Sporadic Amyotrophic Lateral SclerosisNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,236,744May 15, 2019May 31, 2029WATTS, JONATHAN Kreporter.nih.gov
Genetic and Structural Basis for Virus Neutralization of ParamyxovirusesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,230,785September 16, 2024September 15, 2027reporter.nih.gov
Targeting innate immunity for induction of robust renal allograft toleranceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,224,166July 25, 2023April 30, 2028KAWAI, TATSUOreporter.nih.gov
Targeting HIV-specific T cell differentiation programs to enhance post-treatment control of HIVNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,224,130January 19, 2022December 31, 2026RUTISHAUSER, RACHEL LENAreporter.nih.gov
Defining the β-catenin/CBP-catenin/CBP axis in head and neck cancerNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,223,525December 7, 2020November 30, 2026KUKURUZINSKA, MARIA A.reporter.nih.gov
Developing second generation SCID pig models: filling the gaps to improve translation of therapeutics in regenerative medicineNIHOffice of the Director, National Institutes of Health2021 to 2025$3,219,338February 15, 2020July 31, 2029TUGGLE, CHRISTOPHERreporter.nih.gov
Regulation of Epidermal Development and Differentiation-RenewalNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,204,420January 1, 1983May 31, 2026FUCHS, ELAINEreporter.nih.gov
Reprogramming and Directed Differentiation of Skeletal Muscle Cells from hPSCsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,204,262September 20, 2013June 30, 2028PYLE, APRIL Dreporter.nih.gov
Directing Fate, Subtype Identity and Survival in Human Pluripotent-Derived Midbrain Dopamine NeuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,203,281April 1, 2021March 31, 2027STUDER, LORENZ P.reporter.nih.gov
Novel Molecular Biomarkers of Bone MicroarchitectureNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,202,138September 30, 1991March 31, 2027KIEL, DOUGLAS P.reporter.nih.gov
Roles and regulation of tissue resident CD8 T cells during a persistent viral infectionNIHNational Institute of Allergy and Infectious Diseases2025$3,194,992July 16, 2025June 30, 2029ZUNIGA, ELINA Ireporter.nih.gov
Mechanism of chromatin accessibility, 3D chromosome organization, and their functions in gene regulationNIHNational Institute of General Medical Sciences2021 to 2025$3,190,319January 1, 2021December 31, 2026BAI, LUreporter.nih.gov
Assessing Effects of Microgravity on Cardiovascular Aging with AI and 3D OrganoidsNIHNational Center for Advancing Translational Sciences2025$3,183,188August 1, 2025June 30, 2028WU, JOSEPH C.reporter.nih.gov
Regulation of Growth and MorphogenesisNIHNational Institute of General Medical Sciences2021 to 2025$3,183,036May 1, 2019April 30, 2029IRVINE, KENNETH Dreporter.nih.gov
Progenitors, Mechanisms of Differentiation, and Functions of Lung M CellsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,180,672August 1, 2022July 31, 2026RAJAGOPAL, JAYARAJreporter.nih.gov
Developing preclinical xenograft models in zebrafish.NIHOffice of the Director, National Institutes of Health2022 to 2025$3,178,512March 1, 2022February 28, 2026LANGENAU, DAVID MICHAELreporter.nih.gov
Single-cell Multi-omic Profiling of Drug Responses Using Pooled iPSC-CM DifferentiationNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,175,574May 1, 2019April 30, 2027WU, JOSEPH C.reporter.nih.gov
Autologous BM-MSCs and Islet Co-transplantation to Enhance Islet Survival and Function in TP-IAT PatientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,169,762August 24, 2021May 31, 2027WANG, HONGJUNreporter.nih.gov
Hematopoietic Stem Cell And Cord Blood TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,169,146September 30, 2005May 31, 2030PETERSDORF, EFFIE Wreporter.nih.gov
Microphysiological Model of Human Cardiac Sympathetic InnervationNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,165,021July 1, 2022June 30, 2027KIM, DEOK-HOreporter.nih.gov
Advancing Targeted Therapies for Cushing's Disease Using Pituitary Neuroendocrine Tumor OrganoidsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,162,826September 12, 2025August 31, 2029ZAVROS, YANAreporter.nih.gov
Cellular Reinnervation Therapy for Vocal Fold ParalysisNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,161,418August 4, 2021May 31, 2027HALUM, STACEY L.reporter.nih.gov
Immunomodulation by splenic megakaryocytes and platelets in sepsisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,151,437June 7, 2022May 31, 2027LOONEY, MARK ROBERTSreporter.nih.gov
A new brain organoid model for NeuroHIV and the impact of opioidsNIHNational Institute on Drug Abuse2022 to 2025$3,149,557September 30, 2022August 31, 2027MUOTRI, ALYSSON R.reporter.nih.gov
Engineering Vascularized Cardiac MuscleNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,149,452July 1, 2005March 31, 2027VUNJAK-NOVAKOVIC, GORDANAreporter.nih.gov
Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and AutismNIHNational Institute of Mental Health2022 to 2025$3,142,634March 5, 2022December 31, 2026MUOTRI, ALYSSON R.reporter.nih.gov
Harnessing Novel Human Endocrine Progenitor Biology for Enhanced Generation of Beta Cells from Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$3,140,632September 1, 2025August 31, 2029SNEDDON, JULIE BETHreporter.nih.gov
Cellular Therapy for Type 1 Diabetes using Mesenchymal Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,134,067June 1, 2019March 31, 2027WANG, HONGJUNreporter.nih.gov
Correlating molecular behavioral phenotypes in a marmoset model of Huntingtons diseaseNIHNational Institute on Drug Abuse2021 to 2025$3,130,636August 1, 2021May 31, 2026BRIVANLOU, ALI Hreporter.nih.gov
A DUAL CHIMERIC HUMAN ASTROGLIAL-MICROGLIAL MODEL OF HIV AND HANDNIHNational Institute on Drug Abuse2021 to 2025$3,125,946August 1, 2021May 31, 2026GOLDMAN, STEVEN ALANreporter.nih.gov
PFAS exposure is detrimental to placental function and fetal development by disrupting mitochondrial function and metabolismNIHNational Institute of Environmental Health Sciences2025$3,121,590September 5, 2025September 4, 2029FENG, LIPINGreporter.nih.gov
Parametric Response Mapping (PRM) for the detection of chronic lung injury in hematopoietic cell transplant recipientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,121,383August 15, 2022July 31, 2026YANIK, GREGORY Areporter.nih.gov
Defective heme transport in the development of congenital hydrocephalusNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,120,419September 1, 2021June 30, 2026ARNOLD, THOMAS DARMODYreporter.nih.gov
Multi-ethnic high-throughput study to identify novel non-HLA genetic contributors to mortality after blood and marrow transplantationNIHNational Cancer Institute2021 to 2025$3,120,296August 1, 2021July 31, 2027HAHN, THERESA Ereporter.nih.gov
Establishment of a causal link between AD and L1 retrotransposonsNIHNational Institute on Aging2022 to 2025$3,120,084September 15, 2022July 31, 2027MUOTRI, ALYSSON R.reporter.nih.gov
ASH1L mediated transcription networks in autism spectrum disordersNIHNational Institute of Mental Health2023 to 2025$3,119,859January 1, 2023December 31, 2026LIZARRAGA, SOFIA BEATRIZreporter.nih.gov
Gvl mHA Specific T Cell Responses Prevent AML Relapse Following Allogeneic Stem Cell Transplantation.NIHNational Cancer Institute2021 to 2025$3,119,515July 1, 2020June 30, 2027VINCENT, BENJAMIN Greporter.nih.gov
Penetrating the “Black box”: Prediction of early Bronchiolitis obliterans in Pediatric Hematopoietic Stem Cell Transplant RecipientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,117,523July 15, 2021April 30, 2027MYERS, KASIANIreporter.nih.gov
Neural stem cell rejuvenation through single cell pharmacogenomicsNIHNational Institute on Aging2022 to 2025$3,117,021June 15, 2022February 28, 2027BONAGUIDI, MICHAELreporter.nih.gov
Hippocampal iPSC-Derived Assembloids to Model Interneuron and Circuit Vulnerability in Genetically-Encoded Amnestic and Behavioral DementiaNIHNational Institute of Neurological Disorders and Stroke2025$3,109,857August 1, 2025July 31, 2029REXACH, JESSICA Ereporter.nih.gov
Neuronal Autophagy: a Cell-Autonomous Protection MechanismNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,106,444April 1, 2008January 31, 2028YUE, ZHENYUreporter.nih.gov
Mechanisms that couple irregular development of fetal melanoblasts to premature exhaustion of adult melanocyte stem cellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,102,648August 4, 2021May 31, 2027ADAMS, PETER D.reporter.nih.gov
A beneficial persistent DNA damage-induced immune response in agingNIHNational Institute on Aging2025$3,101,237September 1, 2025August 31, 2029DU, WEIreporter.nih.gov
Vascularized NICHE with local immunosuppression for cell replacement for Type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,096,729September 12, 2022May 31, 2027GRATTONI, ALESSANDROreporter.nih.gov
Functional Characterization of LncRNAs Involved in Pluripotency or DifferentiationNIHNational Institute of General Medical Sciences2021 to 2025$3,095,040August 20, 2019March 31, 2030SPECTOR, DAVID Lreporter.nih.gov
Development of iPSCs for comparative genomics in primatesNIHNational Human Genome Research Institute2021 to 2025$3,092,654September 1, 2019April 30, 2027GILAD, YOAVreporter.nih.gov
Lineage Progression of Cortical Neural Stem CellsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$3,090,762May 15, 2015July 31, 2027CHEN, BINreporter.nih.gov
Pathogenic monocyte response to chronic lung inflammation in cystic fibrosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,086,283January 1, 2022November 30, 2026BRUSCIA, EMANUELA MARINAreporter.nih.gov
Privileged and primitive hematopoietic stem cells, niches, and regulatory T cellsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,081,005December 1, 2021November 30, 2025FUJISAKI, JOJIreporter.nih.gov
Anti-inflammatory Cell Based Repair of Intervertebral Disc DegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,075,117September 1, 2021August 31, 2026CHAHINE, NADEEN O.reporter.nih.gov
Mechanisms and Function of Myonuclear PositioningNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,074,996September 1, 2014January 31, 2027BAYLIES, MARY Kreporter.nih.gov
BIOLOGICAL EMBEDDING OF CONTEXTUAL FACTORS IN HUMAN STEM CELLS: IMPLICATIONS FOR POPULATION HEALTH DIFFERENCESNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,074,250September 26, 2022June 30, 2027WADHWA, PATHIK Dreporter.nih.gov
Mechanism of stathmin-2-dependent axon maintenance, regeneration, and functionNIHNational Institute of Neurological Disorders and Stroke2025$3,072,075April 1, 2020March 31, 2029CLEVELAND, DON Wreporter.nih.gov
A transdisciplinary approach for dissecting stem cell states in prostate cancerNIHNational Cancer Institute2021 to 2025$3,070,312September 20, 2021August 31, 2026RABADAN, RAULreporter.nih.gov
Role of the Cell Death Machinery in a Somatic Autoinflammatory SyndromeNIHNational Institute of Allergy and Infectious Diseases2025$3,066,524August 21, 2025July 31, 2029GITLIN, ALEXANDERreporter.nih.gov
Targeting physical stress-driven mechanisms to overcome glioblastoma treatment resistanceNIHNational Cancer Institute2021 to 2025$3,062,772September 22, 2021August 31, 2026MUNN, LANCE L.reporter.nih.gov
First Aid Medicine to Treat Vesicant Induced Corneal InjuryNIHNational Eye Institute2022 to 2025$3,055,554September 30, 2022August 31, 2027CHANDLER, HEATHERreporter.nih.gov
Molecular and Cellular Basis of CraniosynostosisNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,051,443July 1, 2016July 31, 2026CRUMP, GAGE Dreporter.nih.gov
Microengineering vascularized and innervated bone-like scaffolds as an alternative to autologous bone graftsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,048,776August 1, 2021April 30, 2027BERTASSONI, LUIZ EDUARDOreporter.nih.gov
Using MR Spectroscopy to Measure Mammalian Neurogenesis in VivoNIHNational Institute on Aging2022 to 2025$3,042,523June 1, 2022February 28, 2027MALETIC-SAVATIC, MIRJANAreporter.nih.gov
The emerging role of apelin, RAAS, and ACE2 crosstalk in pulmonary hypertensionNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,037,281August 1, 2022July 31, 2027FRUMP, ANDREA LEEreporter.nih.gov
Control of cell proliferation and differentiation by growth pathwaysNIHNational Institute of General Medical Sciences2021 to 2025$3,036,731May 1, 2019April 30, 2029FROLOV, MAXIMreporter.nih.gov
Hippocampal neurogenesis in cognitive function and dysfunction in Alzheimer's disease.NIHNational Institute on Aging2022 to 2025$3,035,322May 15, 2022April 30, 2027LAZAROV, ORLYreporter.nih.gov
Assessing Genomic, Regulatory and Transcriptional Variation at Single Nuclei Resolution in the Brains of Individuals with Autism Spectrum DisorderNIHNational Institute of Mental Health2021 to 2025$3,034,663July 27, 2021May 31, 2027NOWAKOWSKI, TOMASZreporter.nih.gov
Molecular Drivers of Human GliogenesisNIHNational Institute of Mental Health2021 to 2025$3,033,949August 1, 2021May 31, 2026SLOAN, STEVEN Areporter.nih.gov
Early cardiac progenitorsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,025,531July 1, 2013July 31, 2029BRUNEAU, BENOIT GAETANreporter.nih.gov
Modeling Inner Ear Differentiation with Pluripotent Stem CellsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,024,653March 1, 2014May 31, 2029HASHINO, ERIreporter.nih.gov
Heightened hypoxia and DNA methylation in heart defects of diabetic embryopathyNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,020,733September 15, 2022July 31, 2027YANG, PEIXINreporter.nih.gov
Development of ultra-efficient antibodies for single cell mapping applicationsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,018,104March 10, 2023February 28, 2026JOHNSTONE, ANDREA LYNNreporter.nih.gov
Mechanisms and rescue of craniosynostosis associated with gene-environment interactionNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,011,888July 1, 2021April 30, 2027CHEN, JIANFUreporter.nih.gov
Engineering multi-lineage inner ear organoidsNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$3,010,274December 1, 2018June 30, 2025KOEHLER, KARL RUSSELLreporter.nih.gov
Cell-Type Specific Mechanisms of Mitral Valve ProlapseNIHNational Heart, Lung, and Blood Institute2025$3,008,247September 1, 2025August 31, 2029CHI, NEIL Creporter.nih.gov
Generating Exogenic Organs for Transplantation without the Use of ImmunosuppressionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,005,890September 21, 2022July 31, 2027STEER, CLIFFORD JOHNreporter.nih.gov
Mechanisms of T Cell Quiescence and ExhaustionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,001,713March 1, 2019February 28, 2029SARKAR, SUROJITreporter.nih.gov
In vivo Characterization of Regulatory Variant Pathogenicity in Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,998,900January 1, 2022December 31, 2026VISEL, AXELreporter.nih.gov
Pax6 as a key regulator of lens developmentNIHNational Eye Institute2021 to 2025$2,996,871January 1, 2000May 31, 2026CVEKL, ALESreporter.nih.gov
(PQ6) Mesenchymal stem cell based and immunocompetent mouse models of HIV/AIDS KSHV-driven sarcomagenesisNIHNational Cancer Institute2021 to 2025$2,993,160April 8, 2021March 31, 2027SHEMBADE, NOULA DATTUreporter.nih.gov
Targeting MicroRNAs to Eradicate Leukemia Stem CellsNIHNational Cancer Institute2021 to 2025$2,990,517August 1, 2017July 31, 2027KUO, YA-HUEIreporter.nih.gov
Role of an Aberrant N6-Methyladenosine-LncRNA Axis in the Development and Maintenance of Drug Resistance through Regulating the Leukemia Stem CellNIHNational Cancer Institute2022 to 2025$2,988,832September 12, 2022August 31, 2027LIU, SHUJUNreporter.nih.gov
Adhesion GPCR regulation of acute myeloid leukemia stem cells - Resubmission - 1NIHNational Cancer Institute2021 to 2025$2,988,590March 1, 2021February 28, 2026PARK, CHRISTOPHER Yreporter.nih.gov
Adhesion G Protein-Coupled Receptors in CNS Development and RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,987,194September 30, 2015May 31, 2027PIAO, XIANHUAreporter.nih.gov
Targeting TET DNA Dioxygenases as Therapeutic Principle in Myeloid NeoplasmsNIHNational Cancer Institute2021 to 2025$2,986,870July 1, 2021June 30, 2026MACIEJEWSKI, JAROSLAW P.reporter.nih.gov
Unraveling the Genetic Programs Engaged in ASD Neurons Through Coupled Transcriptomic and Phenotypic ReadoutsNIHNational Institute of Mental Health2022 to 2025$2,986,134August 10, 2022June 30, 2027FARHI, SAMOUILreporter.nih.gov
Stem Cell and Transplantation BiologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,984,057August 1, 2015July 31, 2028STIREWALT, DEREK Lreporter.nih.gov
Genetically-engineered stem cells for self-regulating arthritis therapyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,983,611April 1, 2022March 31, 2027GUILAK, FARSHIDreporter.nih.gov
Blood vessel assembly from multipotent hemangioma-derived stem cellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,982,138April 1, 2009April 30, 2028BISCHOFF, JOYCE E.reporter.nih.gov
Investigating the role of Alzheimer's disease familial mutations in neuromuscular physiologyNIHNational Institute on Aging2022 to 2025$2,980,194May 15, 2022April 30, 2027HICKMAN, JAMES Jreporter.nih.gov
Specialized Translational Control of Stem Cell Differentiation and Embryonic DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,979,836March 15, 2016March 31, 2026BARNA, MARIAreporter.nih.gov
Alzheimer's Disease associated pathology induced by neurotropic viral infectionNIHNational Institute on Aging2021 to 2025$2,972,109September 30, 2021August 31, 2027MURPHY, EAIN Areporter.nih.gov
Integration and functionality of retinal organoid transplantsNIHNational Eye Institute2021 to 2025$2,971,351May 1, 2021March 31, 2027SEILER, MAGDALENE Jreporter.nih.gov
Developmental programming of adult stem cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,970,076September 15, 2025September 14, 2029MANA, MIYEKOreporter.nih.gov
Defining the role of histone H3K4 mono-methyltransferase dysfunction in urothelial carcinomaNIHNational Cancer Institute2022 to 2025$2,969,354September 1, 2025August 31, 2027CHEN, YUreporter.nih.gov
Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Cell Transplant RecipientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,966,978December 1, 2021November 30, 2026CHENG, GUANG-SHINGreporter.nih.gov
Systems biology of intratumoral heterogeneity in glioblastomaNIHNational Cancer Institute2022 to 2025$2,962,426January 1, 2022December 31, 2026BALIGA, NITIN Sreporter.nih.gov
Cell Fate Decisions in Epithelial Stem Cell LineagesNIHNational Institute of General Medical Sciences2021 to 2025$2,957,506July 1, 2020May 31, 2030NYSTUL, TODDreporter.nih.gov
Therapeutic Targets for Niemann-Pick Type C NeurodegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,954,773August 15, 2021July 31, 2026LIEBERMAN, ANDREW Preporter.nih.gov
Preclinical studies of pluripotent stem cell-derived myogenic progenitors in non-human primatesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,948,443August 6, 2021December 31, 2026PERLINGEIRO, RITA C. R.reporter.nih.gov
Defining the cause and consequence of aging-specific platelet specification from hematopoietic stem cellsNIHNational Institute on Aging2021 to 2025$2,943,876September 15, 2019May 31, 2029FORSBERG, CAMILLAreporter.nih.gov
Clonal hematopoiesis, inflammasomes and atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,941,081February 15, 2021January 31, 2029TALL, ALAN RICHARDreporter.nih.gov
Regulation of hematopoiesis by ribosomal protein paralogsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,934,669February 1, 2025January 31, 2030WIEST, DAVID L.reporter.nih.gov
Backtracking Leukemia-Typical Somatic Alterations in Cord Blood at Single-cell ResolutionNIHNational Cancer Institute2021 to 2025$2,927,357August 1, 2021July 31, 2026SPECTOR, LOGAN G.reporter.nih.gov
Specification, Molecular Control and Niche Functions of the Hair Follicle MesenchymeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,922,092September 15, 2016August 31, 2026RENDL, MICHAELreporter.nih.gov
Tissue Engineered Rostral Migratory Stream for Directed Neuronal ReplacementNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,919,684April 1, 2021March 31, 2026CULLEN, DANIEL KACYreporter.nih.gov
Mechanisms of epitranscriptomic regulation in cancerNIHNational Cancer Institute2021 to 2025$2,917,446September 10, 2014August 31, 2029JAFFREY, SAMIE Rreporter.nih.gov
Modeling myelodysplasiaNIHNational Cancer Institute2021 to 2025$2,916,597January 1, 2021December 31, 2026GRIMES, H. LEIGHTONreporter.nih.gov
RIGERR: Resources for Investigating Genetic and Epigenetic Regulation of Renal DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,915,414August 3, 2023July 31, 2027LIANG, MINGYUreporter.nih.gov
Identification of metabolic alterations during cortical development in a human cellular model for 22q11.2 deletion syndromeNIHNational Institute of Mental Health2022 to 2025$2,912,854January 18, 2022October 31, 2026PASCA, ANCA MIRABELAreporter.nih.gov
RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,911,488July 1, 2022June 30, 2027HEITMAN, JOSEPHreporter.nih.gov
iPSC-Derived Vascularized Human Lung Organoids and Interaction Between Lung Endothelial Cells and Alveolar Epithelial CellsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,907,792August 1, 2022May 31, 2027REHMAN, JALEESreporter.nih.gov
Assessing the Interplay Between Inflammatory Signaling and Epigenetic Dysregulation in Age-associated Clonal Hematopoiesis and Leukemia InitiationNIHNational Institute on Aging2021 to 2025$2,907,195September 15, 2021June 30, 2027TROWBRIDGE, JENNIFER JEANreporter.nih.gov
iSTAR TregsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,906,574July 1, 2023June 30, 2027TANG, QIZHIreporter.nih.gov
The DNA damage response of fast-cycling erythroblastsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,899,464August 25, 2021October 31, 2026SOCOLOVSKY, MERAVreporter.nih.gov
Alterations in Post-Receptor Insulin Signaling in Diabetes and Insulin ResistanceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,895,718September 17, 2021June 30, 2027KAHN, C RONALDreporter.nih.gov
Dissecting Yersinia Yop Targets in NeutrophilsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,883,504February 11, 2022January 31, 2027MECSAS, JOAN Creporter.nih.gov
Elucidating the molecular mechanisms behind human neurodevelopmental disorders using brain organoidsNIHNational Institute of Mental Health2022 to 2025$2,876,812February 16, 2022December 31, 2026NOVITCH, BENNETT Greporter.nih.gov
Metabolic control of normal and malignant hematopoiesisNIHNational Cancer Institute2021 to 2025$2,869,404September 1, 2020May 31, 2027INTLEKOFER, ANDREW MICHAELreporter.nih.gov
WNT1 Function in Stem Cells in Osteogenesis Imperfecta and Craniofacial-Skeletal TissuesNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,862,721September 10, 2021August 31, 2026LEE, BRENDANreporter.nih.gov
Neurotropic herpesvirus envelopment and microtubule-mediated transportNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,862,658March 15, 2017November 30, 2027WILSON, DUNCAN W.reporter.nih.gov
In Vivo Prevention of Murine GVHDNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,859,522July 1, 2022June 30, 2027BLAZAR, BRUCE Rreporter.nih.gov
Uncovering mechanisms of protection from Alzheimer's disease in CHIP using human cohorts and biosamplesNIHNational Institute on Aging2024 to 2025$2,857,034September 17, 2024May 31, 2029JAISWAL, SIDDHARTHAreporter.nih.gov
Functional Determinants of Metastatic DormancyNIHNational Cancer Institute2021 to 2025$2,856,382January 12, 2022June 30, 2026AGUIRRE-GHISO, JULIO A.reporter.nih.gov
Molecular genetic analyses of transcriptional dysregulation in Alzheimers diseaseNIHNational Institute on Aging2022 to 2025$2,855,753July 15, 2022March 31, 2027KIM, JUNGSUreporter.nih.gov
New upstream targets for HIF-1a-mediated regeneration in young and aged animalsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,854,411May 1, 2011May 31, 2027HEBER-KATZ, ELLEN S.reporter.nih.gov
Investigation of the role of ATXN1 in oligodendroglia and neurodegenerative diseasesNIHNational Institute on Aging2022 to 2025$2,847,875March 1, 2022December 31, 2026LIM, JANGHOOreporter.nih.gov
Functional mapping of noncoding regulatory variants in human neuronal subtypes3.NIHNational Institute of Mental Health2022 to 2025$2,846,517March 18, 2022January 31, 2027YANG, NANreporter.nih.gov
Efficacy of a Mindfulness-Based Stress Management Program for Allogeneic HCT CaregiversNIHNational Cancer Institute2021 to 2025$2,839,105April 1, 2021March 31, 2027VINCI, CHRISTINEreporter.nih.gov
Decoding LRH-1 Activity in Gut Regeneration and DifferentiationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,837,160June 14, 2021April 30, 2026BAYRER, JAMESreporter.nih.gov
DEFINING MECHANISMS OF PROGENITOR BALANCE AND NEURONAL CONNECTIVITYNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,836,728May 1, 2020April 30, 2028ANTON, EVA Sreporter.nih.gov
Dissecting the thermogenic adipose nicheNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,835,733September 1, 2022August 31, 2026TSENG, YU-HUAreporter.nih.gov
Modulating Stochastic Gene Expression for Cell-fate Control and TherapeuticsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,833,713June 1, 2014February 28, 2027WEINBERGER, LEOR Sreporter.nih.gov
Expression, Regulation and Function of the SULT1C Carcinogen-Activating EnzymesNIHNational Institute of Environmental Health Sciences2021 to 2025$2,833,481January 8, 2014December 31, 2026RUNGE-MORRIS, MELISSA Areporter.nih.gov
Regulation of protein multi-functionality by 3 UTRsNIHNational Institute of General Medical Sciences2022 to 2025$2,832,000February 14, 2022December 31, 2026MAYR, CHRISTINEreporter.nih.gov
Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease InterventionNIHNational Institute on Aging2022 to 2025$2,827,960April 1, 2022January 31, 2026TSAI, LI-HUEIreporter.nih.gov
Role of VZV Latency Transcript (VLT) and ORF63 in latency and reactivationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,825,270November 17, 2020October 31, 2026KINCHINGTON, PAUL R.reporter.nih.gov
Translational Control of Cardiac ExcitabilityNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,825,151July 15, 2016June 30, 2026ROBERTSON, GAIL Areporter.nih.gov
Investigating human cis-regulatory evolution with hybrid iPS cellsNIHNational Human Genome Research Institute2022 to 2025$2,824,455May 25, 2022March 31, 2026FRASER, HUNTER Breporter.nih.gov
Developing gene therapy strategies to treat alpha thalassemiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,821,947January 1, 2022December 31, 2025MACKENZIE, TIPPIreporter.nih.gov
Cell-Type Specific Mechanisms of HIV CardiomyopathyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,817,007December 6, 2021November 30, 2025CHI, NEIL Creporter.nih.gov
Production of Cultured Red Blood CellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,816,822September 15, 2015March 31, 2029BOUHASSIRA, ERIC E.reporter.nih.gov
Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,816,253July 1, 2016November 30, 2026ZHANG, JIANYIreporter.nih.gov
Exploiting accelerated aging associated with Low Earth Orbit (LEO) environment to gain insights into pathogenesis and treatment of progressive neurological disordersNIHNational Institute on Aging2025$2,815,841September 1, 2025August 31, 2028SETHU, PALANIAPPANreporter.nih.gov
Multimarker surface signatures of human islet derived extracellular vesiclesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,815,725September 22, 2022May 31, 2027ROUTENBERG, DAVID AARONreporter.nih.gov
Analysis of protein interactions in neurodegenerative diseaseNIHNational Institute on Aging2022 to 2025$2,811,410May 1, 2022April 30, 2027YATES III, JOHN Rreporter.nih.gov
The role of the intestinal microbiome in cancer immunotherapyNIHNational Cancer Institute2023 to 2025$2,811,009August 1, 2023July 31, 2030VAN DEN BRINK, MARCEL R Mreporter.nih.gov
Dynamic Interactions of the Ovarian-Fallopian Axis in High Grade Serous Ovarian CancerNIHNational Cancer Institute2021 to 2025$2,809,429July 10, 2019June 30, 2029BURDETTE, JOANNA Ereporter.nih.gov
Prdm3/16 Regulate Chromatin Accessibility to Determine Alveolar MaturationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,805,992July 1, 2022June 30, 2027WHITSETT, JEFFREY Areporter.nih.gov
Chromatin Dynamics During Epithelial CommitmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,805,406September 1, 2024June 30, 2029ORO, ANTHONY Ereporter.nih.gov
Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell TransplantationNIHNational Cancer Institute2022 to 2025$2,804,127July 22, 2022June 30, 2027VALDIMARSDOTTIR, HEIDDISreporter.nih.gov
Biomaterials Strategies to Promote Functional Recovery After Ischemic StrokeNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,801,281March 1, 2020June 30, 2030SEGURA, TATIANAreporter.nih.gov
Cellular and molecular analysis of B lymphocyte development and selectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,800,489June 15, 2014April 30, 2030PEREIRA, JOAOreporter.nih.gov
Neural Circuits, Kinetics and Energetics HTS of Human iPSC-Neurons, -Microglia, and -Astrocytes: AI-Enabled Platform for Target ID, and Drug Discovery and Toxicity (e.g., Cancer Chemo & HIV ARTs)NIHNational Institute of Mental Health2023 to 2025$2,798,182September 1, 2023August 31, 2026PRICE, JEFFREY H.reporter.nih.gov
A premalignant chronology of cell-state variability in basal-like breast cancerNIHNational Cancer Institute2022 to 2025$2,790,901January 1, 2022December 31, 2026JANES, KEVIN Areporter.nih.gov
Regulation of arterial phenotype by perivascular adipose tissue in cardiometabolic diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,788,828July 1, 2018June 30, 2027LIAW, LUCYreporter.nih.gov
Molecular Basis of cDC1 DevelopmentNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,787,883June 17, 2022May 31, 2027MURPHY, KENNETH Mreporter.nih.gov
Investigate the role of extracellular vesicles in promoting the progression of pulmonary lymphangioleiomyomatosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,784,762December 20, 2021November 30, 2026KARBOWNICZEK, MAGDALENAreporter.nih.gov
Targeting vascular dysfunction to promote lung repair and fibrosis resolutionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,782,716March 5, 2022February 28, 2027LIGRESTI, GIOVANNIreporter.nih.gov
Understanding Hirschsprung disease using hPSC-derived models of the enteric nervous systemNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,781,801September 15, 2025September 14, 2029FATTAHI, FARANAKreporter.nih.gov
Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,778,087July 1, 2022April 30, 2027GRATTONI, ALESSANDROreporter.nih.gov
Defining the role of MafA in islet beta cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,772,028July 29, 2011May 31, 2027STEIN, ROLAND Wreporter.nih.gov
Developmental Exposures, Stem Cell Reprogramming, and Breast Cancer DisparitiesNIHNational Institute of Environmental Health Sciences2021 to 2025$2,767,677January 1, 2018October 31, 2027COLACINO, JUSTIN ADAMreporter.nih.gov
Exploring the role of ATP1A3 mutations in sudden unexplained death in epilepsyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,764,922August 22, 2022June 30, 2027LANDSTROM, ANDREW P.reporter.nih.gov
Mechanisms and Impact of Pregnancy-Induced Adaptations in Pelvic Floor MusclesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,761,892August 1, 2017June 30, 2026ALPERIN, MARIANNAreporter.nih.gov
TMPRSS2 as a potential target for treatments of COVID-19 and respiratory infectious viruses in lungNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,759,863September 1, 2022August 31, 2026CHEN, YA-WENreporter.nih.gov
Base-Edited Hematopoietic Stem and Progenitor Cells To Enable Safe Use Of Highly Potent CD33-Targeted RadioimmunotherapyNIHNational Cancer Institute2022 to 2025$2,758,516July 1, 2022June 30, 2027WALTER, ROLAND BRUNOreporter.nih.gov
Computational and Experimental Modeling of Cardiomyocyte ProliferationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,757,722January 1, 2022December 31, 2026SAUCERMAN, JEFFREY J.reporter.nih.gov
Identification, Quantification, and Functional Characterization of Transporters in Human Placenta, Developing Gut and Fetal BrainNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$2,755,586August 11, 2023June 30, 2028WANG, JOANNEreporter.nih.gov
Functional Biointegration of Bioengineered Salivary Tissues in Irradiated Animal ModelsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,754,807September 19, 2022June 30, 2027FARACH-CARSON, MARY Creporter.nih.gov
Image-guided combination therapies for radiotherapy-induced neurocognitive impairment in pediatric brain tumor survivorsNIHNational Cancer Institute2021 to 2025$2,750,972July 12, 2021June 30, 2027NGEN, ETHEL JOSOreporter.nih.gov
In vivo HSC gene therapy using a multi-modular HDAd vector for HIV cureNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,743,808January 10, 2023December 31, 2027LIEBER, ANDRE MICHAELreporter.nih.gov
Robust mapping of chromatin loops from sparse or single cell Hi-C data with DeepLoopNIHNational Human Genome Research Institute2021 to 2025$2,742,397August 3, 2017May 31, 2027JIN, FULAIreporter.nih.gov
Cadherin-Dependent Regulation of Satellite Cell FunctionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,741,976July 15, 2016June 30, 2027KRAUSS, ROBERT S.reporter.nih.gov
Benzodiazepine mediated mechanisms of transcriptional semi-quiescence in discrete myeloid populationsNIHNational Institute on Drug Abuse2022 to 2025$2,741,871September 15, 2022June 30, 2027GASKILL, PETER JESSEreporter.nih.gov
Targeting off-the-shelf iPSC-derived natural killer cells against solid tumorsNIHNational Cancer Institute2023 to 2025$2,739,146August 1, 2023July 31, 2030MILLER, JEFFREY S.reporter.nih.gov
Human Induced Pluripotent Stem Cells for Cardiovascular Disease ModelingNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,737,027May 1, 2012March 31, 2027WU, JOSEPH C.reporter.nih.gov
Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 MedulloblastomaNIHNational Cancer Institute2022 to 2025$2,726,662April 4, 2011August 31, 2027WECHSLER-REYA, ROBERT J.reporter.nih.gov
Charting the differentiation topology of SF3B1 mutated clonal hematopoiesis (CH) and myelodysplastic syndromes (MDS) via a multi-omics single-cell toolkitNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,726,409February 15, 2022January 31, 2026LANDAU, DANreporter.nih.gov
Three-model platform for understanding DMD epigenetic mechanisms and advancing small molecule therapiesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,725,938February 4, 2021December 31, 2026MAVES, LISAreporter.nih.gov
Functional Characterization of ABCA3 Genomic VariantsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,725,575February 15, 2020June 30, 2030WAMBACH, JENNIFERreporter.nih.gov
In Vitro Human Tissue-Engineered Blood Vessel Disease Model of ProgeriaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,720,700August 1, 2017April 30, 2027TRUSKEY, GEORGE Areporter.nih.gov
Mechanism of Matrix Gla Protein (MGP); Adipose FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,719,728April 24, 2006June 30, 2027BOSTROM, KRISTINA Ireporter.nih.gov
Neutralizing the degenerate disc microenvironment to enhance the efficacy of therapeutic stem cellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,717,504February 1, 2021December 31, 2026SMITH, LACHLAN JAMESreporter.nih.gov
Innovative therapeutic approaches to address excitotoxic CNS/neuronal damage in opioid-neuroHIV comorbidityNIHNational Institute on Drug Abuse2022 to 2025$2,714,944August 15, 2022May 31, 2027HAUSER, KURT Freporter.nih.gov
Modeling ASD-linked genetic mutations in 3D human brain organoidsNIHNational Institute of Mental Health2021 to 2025$2,714,855February 1, 2018June 30, 2029ARLOTTA, PAOLAreporter.nih.gov
Truncated O-glycan-dependent mechanisms inducing metastatic dissemination in pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,714,234August 12, 2022July 31, 2027PONNUSAMY, MOORTHY P.reporter.nih.gov
Development of the resident macrophage lineage in mouse and humanNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,710,279February 8, 2017December 31, 2027GEISSMANN, FREDERICreporter.nih.gov
Metabolic and Hormonal Mechanisms of VCIDNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,707,906April 15, 2019August 31, 2029ZULOAGA, KRISTEN LEANNEreporter.nih.gov
Regulation of T cell exhaustion via 3D chromatin architectureNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,704,065March 15, 2015April 30, 2030XUE, HAI-HUIreporter.nih.gov
Mitochondrial Regulation of Hematopoietic Stem CellsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,703,143January 17, 2017December 31, 2025SNOECK, HANS-WILLEM Ereporter.nih.gov
The impact of inherited and modifiable risk factors on clonal hematopoiesis and age-related diseaseNIHNational Institute on Aging2024 to 2025$2,701,324September 1, 2024June 30, 2029BOLTON, KELLY LEIGHreporter.nih.gov
New roles of endothelial regrowth in ischemic tissue recovery and regenerationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,697,119April 1, 2022March 31, 2027KUME, TSUTOMUreporter.nih.gov
Regulation of DNA methylation by TETs and QSER1NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,694,857September 22, 2022August 31, 2027EVANS, TODD Rreporter.nih.gov
Emergency Myelopoiesis in the Pathogenesis of Myeloid MalignanciesNIHNational Cancer Institute2021 to 2025$2,690,224August 1, 2021July 31, 2027PASSEGUE, EMMANUELLEreporter.nih.gov
Understanding the impact of Clusterin on the oligodendrocyte lineage in ADNIHNational Institute on Aging2022 to 2025$2,688,657September 15, 2022August 31, 2027GAULTIER, ALBAN Preporter.nih.gov
Clinical Significance of MHC Haplotypes in HCTNIHNational Cancer Institute2021 to 2025$2,687,420March 1, 2003August 31, 2028PETERSDORF, EFFIE Wreporter.nih.gov
A Phase II Controlled Trial of Allogeneic Mesenchymal Stromal Cells for the Treatment of Refractory Lupus (MiSLE)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,684,733August 1, 2024May 31, 2027GILKESON, GARY Sreporter.nih.gov
Establishment of a Human Microphysiological System to Elucidate Cellular Mechanisms Underlying Vulnerability to ADNIHNational Institute of Neurological Disorders and Stroke2025$2,683,965May 1, 2025April 30, 2028YOUNG-PEARSE, TRACY Lreporter.nih.gov
Kidney Injury Molecule-1 in Epithelial RepairNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,678,187June 1, 2005June 30, 2027BONVENTRE, JOSEPH VINCENTreporter.nih.gov
Implementation of an interventional, risk-adapted clinical trial for children with newly diagnosed juvenile myelomonocytic leukemia.NIHNational Cancer Institute2022 to 2025$2,677,641August 1, 2022July 31, 2027STIEGLITZ, ELLIOTreporter.nih.gov
Mechanisms of neuromuscular degeneration in SBMANIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,675,706September 1, 2021May 31, 2027LIEBERMAN, ANDREW Preporter.nih.gov
Cardiomyocyte Non-autonomous Factors and Cardiac Regeneration in Large MammalsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,675,195August 9, 2022June 30, 2027ZHU, WUQIANGreporter.nih.gov
Pathomechanisms of SCN3A-related neurodevelopmental disorderNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,674,943December 1, 2020November 30, 2026GOLDBERG, ETHAN Mreporter.nih.gov
Intraventricular Hemorrhage Disrupts the Blood Brain Barrier in Premature InfantsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,672,389March 1, 2021February 28, 2026BALLABH, PRAVEENreporter.nih.gov
NSR-GENE (Neonatal Seizure Registry, GEnetics of post-Neonatal Epilepsy)NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,671,951March 1, 2022February 28, 2027GLASS, HANNAH CRANLEYreporter.nih.gov
Hematopoietic and Immune Development in the Human ChorionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,664,107April 11, 2022March 31, 2027MUENCH, MARCUS Oreporter.nih.gov
The Molecular Regulatory Mechanism of Tooth Root DevelopmentNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,659,844July 19, 2012April 30, 2029CHAI, YANGreporter.nih.gov
Mechanisms and therapeutic implications of human clonal hematopoiesis (CH) mutationsNIHNational Cancer Institute2022 to 2025$2,657,718June 15, 2022May 31, 2027PAPAPETROU, EIRINIreporter.nih.gov
Autoimmune Stem-like CD8 T cells in Type 1 DiabetesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,657,421June 8, 2023May 31, 2028SCHIETINGER, ANDREAreporter.nih.gov
Studies of the fate of the osteoclastNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,655,069June 1, 1995December 31, 2026BOYCE, BRENDAN Freporter.nih.gov
Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,651,127March 16, 2021January 31, 2027BOTCHKAREV, VLADIMIR Areporter.nih.gov
Alveolar Epithelial Cell Dysfunction in Pulmonary Fibrosis: Leveraging SFTPC Mutations for Discovery of Molecular and Cellular TargetsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,642,855July 15, 2019June 30, 2028BEERS, MICHAEL FRANCISreporter.nih.gov
Mechanisms of Hedgehog signaling in glioblastomaNIHNational Cancer Institute2021 to 2025$2,642,438July 1, 2021April 30, 2026RALEIGH, DAVID Rreporter.nih.gov
Regulation of macrophage metabolism in aged muscle during recoveryNIHNational Institute on Aging2022 to 2025$2,642,202May 15, 2022April 30, 2027DRUMMOND, MICAH Jreporter.nih.gov
Modeling human trophoblast-NK cell interactions in term and preterm birthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,640,730April 1, 2021January 31, 2027PARAST, MANA Mreporter.nih.gov
Engineering High-Fidelity Human Cochlear OrganoidsNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$2,639,492July 1, 2022June 30, 2027HASHINO, ERIreporter.nih.gov
Regulation of Skeletal progenitor cells in Osteogenesis ImperfectaNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,636,174July 13, 2022April 30, 2027PARK, DONGSUreporter.nih.gov
Stress and Human Stem/Progenitor Cells: Biobehavioral MechanismsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,635,227August 15, 2022June 30, 2027WADHWA, PATHIK Dreporter.nih.gov
Novel targeted therapy for treating Ovarian CancerNIHNational Cancer Institute2022 to 2025$2,633,406August 1, 2022July 31, 2027VADLAMUDI, RATNA Kreporter.nih.gov
Role of progenitor exhausted CD8 T cells and the progenitor niche in anti-PD1 efficacyNIHNational Cancer Institute2022 to 2025$2,633,070September 1, 2022August 31, 2027HUANG, ALEXANDERreporter.nih.gov
A Bioengineering Approach to Develop a Laminar 3D Cerebellar Neuronal Circuit for Modeling Human CerebellumNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,630,611April 15, 2022March 31, 2027MILLEN, KATHLEEN JOYCEreporter.nih.gov
Identification and characterization of mCpH binding proteins in neuronsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,629,388August 5, 2022July 31, 2027ZHU, HENGreporter.nih.gov
Disease Mechanisms of Pontocerebellar Hypoplasia Type 10NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,628,742July 1, 2021March 17, 2026SCHAFFER, ASHLEIGH Ereporter.nih.gov
Triglycerides as a Predictor of Newborn Subcutaneous and Liver Fat: Contributors to Fetal Fat Accretion in Obese PregnanciesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,620,225May 7, 2021March 31, 2027BARBOUR, LINDA ANNEreporter.nih.gov
Biomechanical Forces and the Enteric Nervous System: Advancing the Development and Function of Tissue-Engineered IntestineNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,618,975September 8, 2025September 7, 2029SPEER, ALLISON LEIGHreporter.nih.gov
Mechanisms of Disease and Treatment in Novel Metabolic Developmental Brain DisordersNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,618,366December 1, 2021November 30, 2026MORROW, ERIC Mreporter.nih.gov
Mechanisms of telomere-induced disease: Role of intestinal malabsorption, barrier dysfunction and dsybiosis.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,617,623June 1, 2022March 31, 2027SAHIN, ERGUNreporter.nih.gov
Bioresorbable Zinc Staples for Anastomoses in the Digestive TractNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,616,912February 3, 2022January 31, 2027ZHU, DONGHUIreporter.nih.gov
Characterizing and Understanding Variation in Gene Regulatory Mechanisms Within and Between SpeciesNIHNational Institute of General Medical Sciences2021 to 2025$2,610,282June 1, 2019May 31, 2029GILAD, YOAVreporter.nih.gov
Eltombopag: Novel Mode of Action on Normal and Aplastic Anemia Hematopoietic Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,608,897August 15, 2022May 31, 2027MACIEJEWSKI, JAROSLAW P.reporter.nih.gov
Transcriptional networks establishing the precise gene expression states that define neurosensory cell identity in the inner earNIHNational Institute on Deafness and Other Communication Disorders2021 to 2025$2,603,881February 1, 2016June 30, 2027XU, PIN-XIANreporter.nih.gov
Pre-IND Development of Polymeric Micelles with Dual Drug Payloads for HCC TherapyNIHNational Cancer Institute2022 to 2025$2,603,837August 1, 2022June 30, 2027LI, CHUNreporter.nih.gov
Cell fate choices by Tbx1 in forming the mammalian heartNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,603,457August 20, 2020April 30, 2029MORROW, BERNICE Ereporter.nih.gov
Marfan Aortic Embryologic Origin Influences Aneurysm FormationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,603,051April 1, 2016March 31, 2027FISCHBEIN, MICHAEL PETERreporter.nih.gov
Genetic Regulatory Network in Craniofacial DevelopmentNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,599,984March 12, 2025January 31, 2030HSU, WEIreporter.nih.gov
Defining Pathogenic Mechanisms and Therapeutic Opportunities for Langerhans Cell HistiocytosisNIHNational Cancer Institute2022 to 2025$2,594,306January 14, 2011December 31, 2026MERAD, MIRIAMreporter.nih.gov
Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle lossNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,591,324March 1, 2021February 28, 2027SHIN, SU RYONreporter.nih.gov
An Interneuron-based Cell Therapy for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,589,602September 1, 2010March 31, 2027BARABAN, SCOTT Creporter.nih.gov
Development of a stem-cell derived thymic cell therapy to treat patients with athymiaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,586,728April 15, 2022January 31, 2027LIM, BINGreporter.nih.gov
Heterogeneity of Satellite Cell Populations Play a Role in Improvements in PAD after Exercise TherapyNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,586,669February 15, 2022January 31, 2027HANSEN, LAURA MARIEreporter.nih.gov
Mechanisms and Modulation of Accelerated Atherosclerosis in Clonal HematopoiesisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,584,743April 1, 2022August 31, 2026LIBBY, PETERreporter.nih.gov
Single Cell Tracking of 3D Epigenetic Landscape Evolution During Embryonic DevelopmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,584,586March 1, 2022February 28, 2027ZHONG, SHENGreporter.nih.gov
Small Molecule Drug Discovery for CLN3 and CLN6 DiseaseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,584,107September 20, 2021June 30, 2027TRIPPIER, PAULreporter.nih.gov
Microribbon scaffold-mediated Immunomodulation for Cranial Bone RepairNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,582,020January 1, 2015May 31, 2027YANG, FANreporter.nih.gov
Cell lineage and transcriptional analysis of the vertebrate neural plate borderNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,580,495February 1, 2018January 31, 2028BRONNER, MARIANNEreporter.nih.gov
ALOX15 regulation of colon cancer invasiveness via PI3P-linoleic acid metabolismNIHNational Cancer Institute2022 to 2025$2,576,142January 1, 2022April 30, 2027SHUREIQI, IMADreporter.nih.gov
Assembly and characterization of human cortico-striatal neural networksNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,570,801August 1, 2021May 31, 2027SHCHEGLOVITOV, OLEKSANDRreporter.nih.gov
VZV vaccine attenuation and the DNA damage responseNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,569,364July 1, 2022June 30, 2027KINCHINGTON, PAUL R.reporter.nih.gov
Site-specific Integration of Large (10-100 kb) DNA Constructs into the Mouse Genome and Human Induced Pluripotent Stem Cells Using the Cas9-Bxb1 Integrase ToolboxNIHNational Cancer Institute2022 to 2025$2,568,438July 1, 2022June 30, 2027HOSUR, VISHNUreporter.nih.gov
Modeling Normal and Abnormal TrophoblastsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,565,353September 25, 2018March 31, 2028SCHULZ, LAURA CLAMONreporter.nih.gov
Regulation of catagen regression and progenitor pruning by the dermal sheathNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,565,274July 1, 2021June 30, 2026RENDL, MICHAELreporter.nih.gov
Impact of mutational order on molecular mechanisms of oncogenesisNIHNational Cancer Institute2022 to 2025$2,563,938May 10, 2022February 28, 2027PAPAPETROU, EIRINIreporter.nih.gov
Bioinspired Mechanically Stiff Hydrogels for Osteochondral Tissue RegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,563,338July 25, 2016March 31, 2027BRYANT, STEPHANIE Jreporter.nih.gov
Zfp423 Mechanisms in Joubert Syndrome and Related DisordersNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,562,908February 1, 2017May 31, 2027HAMILTON, BRUCE Areporter.nih.gov
Mechanisms for Regenerative Healing in Intervertebral DiscsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,560,545January 15, 2022December 31, 2026IATRIDIS, JAMES C.reporter.nih.gov
Defining the mechanisms regulating adipose tissue metabolic memory and its role in rebound weight gain.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,559,138September 7, 2025August 31, 2029MERRICK, DAVID MICHAELreporter.nih.gov
Multimodal Optical Imaging on the Effect of Maternal Polysubstance Exposure on Fetal Brain Microvessel FunctionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,556,302January 1, 2016July 31, 2027LARIN, KIRILL Vreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Stanford UniversityStanford, CA127$180.7 million0$0
University of California, San FranciscoSan Francisco, CA99$157.2 million0$0
University of California, San DiegoLa Jolla, CA94$154.2 million0$0
Columbia University Health SciencesNew York, NY88$150.2 million0$0
University of WashingtonSeattle, WA51$138.7 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY85$136.6 million0$0
Indiana University IndianapolisIndianapolis, IN39$123.8 million0$0
University of PennsylvaniaPhiladelphia, PA96$114.8 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY42$106.5 million0$0
University of Michigan at Ann ArborAnn Arbor, MI90$104.8 million0$0
Duke UniversityDurham, NC65$100.6 million0$0
Washington UniversitySaint Louis, MO69$97.3 million0$0
Massachusetts General HospitalBoston, MA58$94.7 million0$0
Boston Children's HospitalBoston, MA61$88 million0$0
University of Wisconsin-MadisonMadison, WI56$86.9 million0$0
Medical College of WisconsinMilwaukee, WI17$85.3 million0$0
Johns Hopkins UniversityBaltimore, MD68$83.1 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH55$82.6 million0$0
Northwestern University at ChicagoChicago, IL64$80.8 million0$0
University of California Los AngelesLos Angeles, CA52$70 million0$0
Yale UniversityNew Haven, CT51$68.3 million0$0
Brigham and Women's HospitalBoston, MA46$66.8 million0$0
University of Southern CaliforniaLos Angeles, CA44$66.4 million0$0
Albert Einstein College of MedicineBronx, NY44$64.6 million0$0
Ut Southwestern Medical CenterDallas, TX45$64.4 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA41$64.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY50$64.3 million0$0
Baylor College of MedicineHouston, TX48$63 million0$0
University of California-IrvineIrvine, CA42$62.6 million0$0
University of Colorado DenverAurora, CO50$61.7 million0$0
Fred Hutchinson Cancer CenterSeattle, WA33$60.5 million0$0
Emory UniversityAtlanta, GA47$60.1 million0$0
University of MinnesotaMinneapolis, MN41$52.4 million0$0
University of ArizonaTucson, AZ13$51.1 million0$0
University of VirginiaCharlottesville, VA29$50.7 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA31$48.8 million0$0
Boston University Medical CampusBoston, MA27$48.7 million0$0
University of UtahSalt Lake City, UT27$47.9 million0$0
University of Miami School of MedicineCoral Gables, FL20$47.2 million0$0
University of RochesterRochester, NY34$46.9 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC32$46.4 million0$0
University of FloridaGainesville, FL28$44.1 million0$0
Vanderbilt University Medical CenterNashville, TN20$42.9 million0$0
New York University School of MedicineNew York, NY32$42.7 million0$0
University of Illinois at ChicagoChicago, IL34$41.6 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA29$40.7 million0$0
Massachusetts Institute of TechnologyCambridge, MA15$37.5 million0$0
Beckman Research Institute/city of HopeDuarte, CA24$37.2 million0$0
University of California at DavisDavis, CA29$35.8 million0$0
Case Western Reserve UniversityCleveland, OH23$33.5 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ20$33.4 million0$0
University of ChicagoChicago, IL29$33 million0$0
Ohio State UniversityColumbus, OH22$32.3 million0$0
University of Maryland BaltimoreBaltimore, MD21$31 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH22$30.4 million0$0
Rockefeller UniversityNew York, NY14$29.2 million0$0
Columbia UniversityNew York, NY14$27.7 million0$0
National Collegiate Inventors and Innovators AllianceHadley, MA1$27.5 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX22$27.2 million0$0
ST. Jude Children's Research HospitalMemphis, TN20$26.7 million0$0
Oregon Health & Science UniversityPortland, OR25$26.5 million0$0
Medical University of South CarolinaCharleston, SC19$26 million0$0
University of Texas HLTH Science CenterSan Antonio, TX21$25.4 million0$0
Scripps Research Institute, theLa Jolla, CA14$25.3 million0$0
University of TX MD Anderson Can CTRHouston, TX19$25.3 million0$0
The Emmes Company, LLCRockville, MD1$25.3 million0$0
University of Connecticut SCH of Med/dntFarmington, CT18$24.8 million0$0
Buck Institute for Research on AgingNovato, CA6$24 million0$0
Mayo Clinic RochesterRochester, MN19$23.7 million0$0
Jackson LaboratoryBar Harbor, ME10$23.7 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA17$23.3 million0$0
J. David Gladstone InstitutesSan Francisco, CA13$23.1 million0$0
University of Nebraska Medical CenterOmaha, NE12$22.5 million0$0
University of California-Santa CruzSanta Cruz, CA8$22.5 million0$0
Seattle Children's HospitalSeattle, WA14$22.2 million0$0
University of California-BerkeleyBerkeley, CA13$20.4 million0$0
Dana-Farber Cancer InstBoston, MA17$19.6 million0$0
Harvard UniversityCambridge, MA17$19.2 million0$0
University of Colorado at BoulderBoulder, CO12$19.1 million0$0
University of Georgia Research Foundation IncAthens, GA18$19 million0$0
SUNY at Stony BrookStony Brook, NY13$18.8 million0$0
Brown UniversityProvidence, RI10$18.6 million0$0
Vanderbilt UniversityNashville, TN19$18.4 million0$0
University of Alabama at BirminghamBirmingham, AL18$18.4 million0$0
Beth Israel Deaconess Medical CenterBoston, MA8$18.2 million0$0
SUNY at BuffaloAmherst, NY13$18 million0$0
Harvard Medical SchoolBoston, MA22$17.1 million0$0
University of IowaIowa City, IA17$17.1 million0$0
Methodist Hospital Research InstituteHouston, TX8$16.2 million0$0
Mayo Clinic JacksonvilleJacksonville, FL11$15.7 million0$0
Coriell Institute for Medical ResearchCamden, NJ4$14.7 million0$0
Cornell UniversityIthaca, NY14$14.7 million0$0
Rutgers University New BrunswickNew Brunswick, NJ10$14.4 million0$0
Texas A&m University Health Science CTRCollege Station, TX10$13.6 million0$0
University of Kansas Medical CenterKansas City, KS16$13.5 million0$0
Purdue UniversityWest Lafayette, IN10$13.4 million0$0
University of Texas at San AntonioSan Antonio, TX4$13.4 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY9$12.6 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA9$12.6 million0$0
H. Lee Moffitt Cancer CTR & Res InstTampa, FL10$12.2 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20253,819$2,015,156,9610$0
20242,721$1,406,046,0060$0
20231,877$1,064,316,4910$0
20221,276$769,268,5760$0
2021752$453,614,4850$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 64 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 22 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 20 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 5 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 3 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 2 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIHJuly 17, 2027Not listedNotice number printed on 1 award here
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)PA-24-191NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)PA-25-302NIHJanuary 7, 2028$50,000Notice number printed on 1 award here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 493 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 493 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 493 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 493 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 493 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 493 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 493 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 493 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 493 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 493 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 493 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.