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Data / Research funding / Pancreatic Cancer

Pancreatic Cancer: 1,008 NIH awards ($1.1B) to 208 organizations

1,008 NIH awards ($1.1B) in the NIH spending category Pancreatic Cancer, to 208 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 1,008 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Moffitt Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$22,007,955February 18, 1998January 31, 2027CLEVELAND, JOHN L.reporter.nih.gov
Pancreatitis-induced initiation of early onset pancreatic cancerNIHNational Cancer Institute2021 to 2025$15,447,190February 1, 2025January 31, 2026SHAW, REUBENreporter.nih.gov
Chronic Pancreatitis Clinical Research Consortium (CPCRC) Data Coordinating Center (CPCRC-DCC)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$9,632,234September 28, 2015June 30, 2030LI, LIANGreporter.nih.gov
Targeting the A2B Adenosine Receptor for Immunoprevention of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$9,423,468September 15, 2023March 14, 2027WU, XIANGWEIreporter.nih.gov
The role of stem cells and the microenvironment in gastrointestinal cancersNIHNational Cancer Institute2021 to 2025$5,569,272January 7, 2016August 31, 2030WANG, TIMOTHY CRAGINreporter.nih.gov
2/3 Florida-California Cancer Research, Education and Engagement (CaRE2) Health CenterNIHNational Cancer Institute2021 to 2025$5,355,395September 17, 2018August 31, 2028WILKIE, DIANA Jreporter.nih.gov
An atlas of pancreatic tumorigenesis in the context of altered DNA repair occurring in high-risk individualsNIHNational Cancer Institute2024 to 2025$5,050,023September 1, 2024August 31, 2029SEARS, ROSALIE Creporter.nih.gov
Pancreatic Cancer Detection ConsortiumNIHNational Cancer Institute2021 to 2025$5,023,372May 1, 2017August 31, 2027HOLLINGSWORTH, MICHAEL A.reporter.nih.gov
Predicting Pancreatic Ductal Adenocarcinoma (PDAC) Through Artificial Intelligence Analysis of Pre-Diagnostic CT ImagesNIHNational Cancer Institute2021 to 2025$4,827,743September 1, 2021August 31, 2026LI, DEBIAOreporter.nih.gov
Tissue factor-dependent coagulation in thrombosis and immune responsesNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,577,076February 1, 2021January 31, 2028MACKMAN, NIGELreporter.nih.gov
Altered metabolism and machine learning for pancreatic cancer early detectionNIHNational Cancer Institute2021 to 2025$4,100,528September 16, 2022August 31, 2027WOLPIN, BRIAN MATTHEWreporter.nih.gov
Stromal modulation of pancreatic cancer malignant cell state and therapeutic sensitivityNIHNational Cancer Institute2022 to 2025$4,096,241September 19, 2022August 31, 2027HAHN, WILLIAM C.reporter.nih.gov
Exosome-based microRNA biomarkers for Non-invasive and Early Detection of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$4,072,882September 1, 2017July 31, 2028GOEL, AJAYreporter.nih.gov
Implantable iontophoresis chemotherapy delivery device for direct infusion ofgemcitabine into pancreatic adenocarcinoma: Device development and First-in-Human clinical trialNIHNational Cancer Institute2021 to 2022$4,000,000September 17, 2017July 31, 2024DAUNCH, WILLIAM ANDREWreporter.nih.gov
Commercializing CivaSheet for Pancreatic Cancer PatientsNIHNational Cancer Institute2023 to 2025$3,999,206September 13, 2016June 30, 2026PEREZ, KRISTYreporter.nih.gov
Validation of biomarkers for risk prediction and early diagnosis of Pancreatic AdenocarcinomaNIHNational Cancer Institute2021 to 2025$3,998,452May 17, 2016March 31, 2028BRAND, RANDALLreporter.nih.gov
Development of a protein drug for pancreatic cancer treatmentNIHNational Cancer Institute2022 to 2024$3,994,217September 26, 2017January 31, 2025LIU, ZHI-RENreporter.nih.gov
Identifying Metabolic Dependencies of Pancreatic CancersNIHNational Cancer Institute2021 to 2024$3,975,118August 1, 2018July 31, 2025KIMMELMAN, ALECreporter.nih.gov
Fibroblast Heterogeneity in Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,931,956August 10, 2021July 31, 2026TUVESON, DAVID Areporter.nih.gov
Interrogating the Evolutionary Dynamics of Cancer for Clinical Benefit and ActionabilityNIHNational Cancer Institute2021 to 2024$3,915,629August 1, 2018July 31, 2025IACOBUZIO-DONAHUE, CHRISTINE Areporter.nih.gov
Elucidation and targeting of paracrine cascades in PDACNIHNational Cancer Institute2022 to 2025$3,892,796September 1, 2022August 31, 2027OLIVE, KENNETH P.reporter.nih.gov
Human natural killer cells: Advancing biology and clinical applicationsNIHNational Cancer Institute2021 to 2025$3,769,374July 21, 2017June 30, 2032CALIGIURI, MICHAEL Areporter.nih.gov
Mayo Clinic Prospective Resource for Biomarker Validation and Early Detection of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,767,699July 15, 2016August 31, 2027MAJUMDER, SHOUNAKreporter.nih.gov
Studying factors controlling cancer progression and immune recognition in mouse modelsNIHNational Cancer Institute2022 to 2025$3,664,660September 20, 2022August 31, 2029JACKS, TYLER E.reporter.nih.gov
Using markers to improve pancreatic cancer screening and surveillance: a multi-center studyNIHNational Cancer Institute2021 to 2025$3,641,472July 18, 2016August 31, 2027GOGGINS, MICHAEL G.reporter.nih.gov
Molecular strategies for early detection and targeting of cancerNIHNational Cancer Institute2022 to 2025$3,640,759August 12, 2015July 31, 2028REYA, TANNISHTHAreporter.nih.gov
Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Uncover Hidden BiologyNIHNational Cancer Institute2021 to 2025$3,589,331July 1, 2019August 31, 2026PERMUTH, JENNIFER Breporter.nih.gov
Targeting undruggable RAS for cancer treatmentNIHNational Cancer Institute2021 to 2024$3,589,157September 1, 2018August 31, 2025DER, CHANNING J.reporter.nih.gov
Circulating Biomarkers and Imaging for Early Detection of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,563,506August 7, 2018July 31, 2029SEN, SUBRATAreporter.nih.gov
The MYC Transcription Factor Network and the Path to CancerNIHNational Cancer Institute2021 to 2024$3,449,610September 1, 2018August 31, 2025EISENMAN, ROBERT NEILreporter.nih.gov
Multi-modal Liquid Biopsy Early Assessment of Breast Cancer, Pancreatic Cancer, and Multiple MyelomaNIHNational Cancer Institute2023 to 2025$3,449,390September 18, 2023August 31, 2028KUHN, PETERreporter.nih.gov
Chemical tools for developmental biologyNIHNational Institute of General Medical Sciences2021 to 2025$3,426,216April 1, 2018June 30, 2028CHEN, JAMES Kreporter.nih.gov
Biology and Function of Exosomes in CancerNIHNational Cancer Institute2022 to 2025$3,385,880September 1, 2022August 31, 2029KALLURI, RAGHUreporter.nih.gov
Real-time MRI-guided adaptive radiotherapy of unresectable pancreatic cancerNIHNational Cancer Institute2021 to 2025$3,323,920August 13, 2021July 31, 2026OTAZO, RICARDOreporter.nih.gov
Fibroblast orchestration of the immune response in pancreatic cancerNIHNational Cancer Institute2022 to 2025$3,286,816September 19, 2022August 31, 2027PASCA DI MAGLIANO, MARINAreporter.nih.gov
Longitudinal Proteomic and Metabolomic Predictors of Pancreatic Cyst Malignant Progression and Early Stage Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,264,543April 1, 2021March 31, 2027SCHMIDT, CHRISTIAN MAXIMILLIANreporter.nih.gov
Clinical Validation Center for Early Detection of Pancreatic CancerNIHNational Cancer Institute2021 to 2024$3,231,816May 4, 2016August 31, 2027MAITRA, ANIRBANreporter.nih.gov
Imaging Modulation of Immune PhenotypeNIHNational Cancer Institute2021 to 2025$3,227,270February 1, 2021January 31, 2027FERRARA, KATHERINE Wreporter.nih.gov
Addressing Chemoresistance in Pancreatic and Ovarian Cancers: Photodynamic Priming and Repurposing of Tetracyclines using Targeted Photo-Activable Multi-Inhibitor LiposomeNIHNational Cancer Institute2021 to 2025$3,218,280April 1, 2021March 31, 2027HUANG, HUANG CHIAOreporter.nih.gov
A Patient-Centric Approach to Advance Functional Precision OncologyNIHNational Cancer Institute2023 to 2025$3,167,628September 22, 2023August 31, 2028KEMP, CHRISTOPHER Jreporter.nih.gov
Spatial functional genomics to identify regulators of the tumor microenvironment and cancer immunityNIHNational Cancer Institute2023 to 2025$3,154,814September 19, 2023August 31, 2028BROWN, BRIAN Dreporter.nih.gov
Leveraging Vulnerabilities Induced by STING Activation in Pancreatic CancerNIHNational Cancer Institute2021 to 2025$3,092,811February 15, 2021January 31, 2026DONAHUE, TIMOTHY Rreporter.nih.gov
Urine and serum biomarkers for early diagnosis and risk assessment of pancreatic cancerNIHNational Cancer Institute2021 to 2025$3,080,631February 3, 2021January 31, 2027LOKSHIN, ANNA E.reporter.nih.gov
Therapeutic Targeting Mitochondrial C1 MetabolismNIHNational Cancer Institute2021 to 2025$3,043,890January 1, 2021December 31, 2026MATHERLY, LARRY Hreporter.nih.gov
Mitigation of Radiation Induced Gastrointestinal Syndrome.NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,026,290August 1, 2023July 31, 2026NORRIS, ANDREW JOHNreporter.nih.gov
Bacterial biosensors for the prevention of gastrointestinal cancersNIHNational Cancer Institute2021 to 2025$2,993,830May 18, 2020April 30, 2029HASTY, JEFF Mreporter.nih.gov
Regulation of PDAC metabolism and immunity by collagen and its cleavage productsNIHNational Cancer Institute2022 to 2025$2,987,434September 21, 2022August 31, 2025KARIN, MICHAELreporter.nih.gov
Targeting KRAS and adenosine mediated immunosuppression in pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,984,199March 1, 2021February 28, 2026RADU, CAIUS GABRIELreporter.nih.gov
Regulation of tumor suppression by alpha-ketoglutarateNIHNational Cancer Institute2021 to 2025$2,938,818August 6, 2025July 31, 2027FINLEY, LYDIAreporter.nih.gov
DIRAS3 disrupts K-RAS clustering and signaling, enhancing autophagy and response to autophagy inhibitionNIHNational Cancer Institute2022 to 2025$2,923,293September 21, 2022August 31, 2027BAST, ROBERT Creporter.nih.gov
PASSCODE (Pancreatic Adenocarcinoma Stromal Reprograming ConSortium COordination, Data Management and Education)NIHNational Cancer Institute2022 to 2024$2,916,000September 16, 2022August 31, 2027MAITRA, ANIRBANreporter.nih.gov
Indiana University (IU) Clinical Center for Chronic Pancreatitis Clinical Research NetworkNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,908,091September 28, 2015June 30, 2030EASLER, JEFFREY JAMESreporter.nih.gov
Molecular Imaging and Theranostics of CancerNIHNational Cancer Institute2021 to 2023$2,907,093September 4, 2017March 31, 2025BHUJWALLA, ZAVER M.reporter.nih.gov
Development of contrast agents to facilitate image-guided surgeryNIHNational Cancer Institute2023 to 2025$2,898,937September 19, 2023February 27, 2026MCNALLY, LACEY Rreporter.nih.gov
The Prognostic Significance and Mechanistic Determination of Chromatin Remodeling Biomarkers in Non-Functional Pancreatic Neuroendocrine TumorNIHNational Cancer Institute2021 to 2025$2,897,842July 15, 2021June 30, 2026SINGHI, AATUR DILIPreporter.nih.gov
Synthetic circuits that drive infiltration of therapeutic T cells into immunologically cold tumorsNIHNational Cancer Institute2021 to 2025$2,872,622September 10, 2021August 31, 2026LIM, WENDELL Areporter.nih.gov
Regulation and Function of Stromal Macropinocytosis in Pancreatic Ductal AdenocarcinomaNIHNational Cancer Institute2021 to 2025$2,871,428September 1, 2021August 31, 2026COMMISSO, COSIMOreporter.nih.gov
Group 2 Innate Lymphoid Cell Regulation of Pancreatic Cancer ImmunityNIHNational Cancer Institute2022 to 2025$2,828,375September 1, 2022August 31, 2027BALACHANDRAN, VINOD Preporter.nih.gov
Re-wiring PDAC Tumor Immunity Through Dendritic CellsNIHNational Cancer Institute2021 to 2025$2,793,464September 22, 2021August 31, 2026DENARDO, DAVID Greporter.nih.gov
Targeting the fibroblast-immune cell crosstalk to relieve immune suppression in the pancreatic cancer microenvironmentNIHNational Cancer Institute2022 to 2025$2,781,650September 1, 2022August 31, 2027PASCA DI MAGLIANO, MARINAreporter.nih.gov
Targeting the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer with a Neoadjuvant Platform Clinical TrialNIHNational Cancer Institute2021 to 2025$2,776,685July 21, 2015June 30, 2026JAFFEE, ELIZABETH M.reporter.nih.gov
CAR T cells targeting mesothelin and secreting bispecific antibodies targeting fibroblasts in pancreatic cancerNIHNational Cancer Institute2023 to 2024$2,756,416August 9, 2023July 31, 2025MAUS, MARCELA VALDERRAMAreporter.nih.gov
Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer TumorsNIHNational Cancer Institute2021 to 2025$2,742,888April 1, 2021March 31, 2027ZAMBONI, WILLIAM Creporter.nih.gov
The Stanford Clinical Center for the Chronic Pancreatitis Research Consortium (CPCRC)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,740,203September 28, 2015June 30, 2030PARK, WALTER GWANG-UPreporter.nih.gov
Engineered anti-PSCA antibodies for immunoPET and targeted therapy of pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,731,178January 1, 2022December 31, 2026WU, ANNA Mreporter.nih.gov
Truncated O-glycan-dependent mechanisms inducing metastatic dissemination in pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,714,234August 12, 2022July 31, 2027PONNUSAMY, MOORTHY P.reporter.nih.gov
Engaging immunosuppressive myeloid cells in the TME for the treatment of pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,712,785May 11, 2021April 30, 2026RAVETCH, JEFFREY VICTORreporter.nih.gov
Imaging Acidosis and Immune Therapy in PDACNIHNational Cancer Institute2021 to 2024$2,672,496February 1, 2020January 31, 2026PILON-THOMAS, SHARIreporter.nih.gov
Interrogating the response of the tumor microenvironment to combination immunotherapy using a microfluidic platformNIHNational Cancer Institute2021 to 2025$2,645,874August 5, 2014April 30, 2027FOLCH, ALBERTreporter.nih.gov
Role of RABL6A-PP2A in neuroendocrine tumorsNIHNational Cancer Institute2021 to 2025$2,626,262May 1, 2021April 30, 2027QUELLE, DAWN Ereporter.nih.gov
Management and Data Coordination Unit for PCDCNIHNational Cancer Institute2022 to 2025$2,593,209September 1, 2022August 31, 2027OBERG, ANN LAURAreporter.nih.gov
Development and Implementation of ElectronicDecision Aids for Genetic Testing in Inherited Cancer SyndromesNIHNational Cancer Institute2021 to 2024$2,589,338September 14, 2020August 31, 2025CHUNG, DANIEL Creporter.nih.gov
Endoplasmic Reticulum-to-Mitochondria Calcium Transfer in Pancreatic Cancer Development, Metastasis, and TreatmentNIHNational Cancer Institute2021 to 2025$2,585,597August 15, 2021July 31, 2026FOSKETT, JAMES KEVINreporter.nih.gov
Stroma penetrating and immune modulating nanoparticles for image-guided therapy of pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,571,973July 1, 2021June 30, 2027YANG, LILYreporter.nih.gov
Pancreatic cancer-associated fibroblasts: function, detection, and regulationNIHNational Cancer Institute2022 to 2025$2,559,695June 1, 2022May 31, 2027CUKIERMAN, EDNAreporter.nih.gov
Linear energy transfer (LET) dependencies for understanding pancreatic tumor control and relevant molecular endpoints in support of RBE-based heavy-ion radiotherapyNIHNational Cancer Institute2021 to 2025$2,554,187January 1, 2021December 31, 2026AMUNDSON, SALLY A.reporter.nih.gov
Quantitative In Vivo 68Ga-Fibroblast-Activation-Protein-Inhibitors (FAPI)-46 PET Imaging of Cancer-Associated Fibroblasts (CAFs) in Pancreatic Ductal Adenocarcinoma (PDA)NIHNational Cancer Institute2022 to 2025$2,539,832September 1, 2022August 31, 2027GOENKA, AJIT HARISHKUMARreporter.nih.gov
Phenotypic marker-guided development of selective antimetastasis therapeutic leadsNIHNational Cancer Institute2022 to 2025$2,538,566July 1, 2022June 30, 2027HUANG, SUIreporter.nih.gov
Mitochondrial calcium signaling in pancreatic cancer metastasis and progressionNIHNational Cancer Institute2022 to 2025$2,532,250March 1, 2022February 28, 2027YANG, SHENGYUreporter.nih.gov
PRedictiOn Algorithms for the DeTECTion of Early Stage Pancreatic Cancer (PRO-TECT)NIHNational Cancer Institute2021 to 2023$2,511,714July 1, 2019June 30, 2025WU, BECHIENreporter.nih.gov
Reprogramming PDAC Stroma by Targeting Coagulation in the Tumor MicroenvironmentNIHNational Cancer Institute2023 to 2025$2,488,832September 1, 2022August 31, 2027HAN, BUMSOOreporter.nih.gov
Relative Immunological Effectiveness (RIE) of Carbon Ion Radiation Therapy for Pancreatic CancerNIHNational Cancer Institute2021 to 2025$2,481,775January 14, 2021December 31, 2026GUHA, CHANDANreporter.nih.gov
Ferroptosis, Cellular Metabolism, and CancerNIHNational Cancer Institute2021 to 2025$2,451,692February 1, 2017August 31, 2027JIANG, XUEJUNreporter.nih.gov
HIFU-immunotherapy in pancreatic cancerNIHNational Cancer Institute2021 to 2024$2,447,185July 1, 2020June 30, 2026FERRARA, KATHERINE Wreporter.nih.gov
Patient-specific, high-sensitivity spectral CT for assessment of pancreatic cancerNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,440,414September 22, 2021June 30, 2026NOËL, PETER Breporter.nih.gov
Mechanisms of Epigenetic Plasticity in PDACNIHNational Cancer Institute2021 to 2025$2,434,090April 1, 2021March 31, 2027YI, CHUNLINGreporter.nih.gov
Surrogate biomarkers for assessing changes in pancreatic cancer tumor microenvironmentNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,423,859September 30, 2021June 30, 2026DOYLEY, MARVIN Mreporter.nih.gov
Targeting stem-like cells and their niche in pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,423,178January 1, 2025December 31, 2026TAMMELA, TUOMASreporter.nih.gov
Understanding and targeting mutant splicing factors in pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,406,506September 21, 2022August 31, 2027ESCOBAR HOYOS, LUISAreporter.nih.gov
Development of a panel of multiplex biomarkers for the early detection of pancreatic ductal adenocarcinoma and high-risk lesionsNIHNational Cancer Institute2023 to 2025$2,404,147July 19, 2023June 30, 2028CHAN, DANIEL WANYUIreporter.nih.gov
Developing new therapeutic strategies for distinct Ras-driven cancersNIHNational Cancer Institute2021 to 2025$2,376,159July 1, 2005March 31, 2027CICHOWSKI, KAREN Mreporter.nih.gov
In situ cancer cell specific biomineralization to overcome nanoparticle delivery barriers and sensitize pancreatic cancer to radiotherapyNIHNational Cancer Institute2022 to 2025$2,362,124August 2, 2022July 31, 2027SOKOLOV, KONSTANTIN Vreporter.nih.gov
Innovations and mechanisms in tumor subcellular metabolismNIHNational Cancer Institute2021 to 2024$2,360,558September 23, 2021August 31, 2026ABU-REMAILEH, MONTHERreporter.nih.gov
Digital Nanoplasmonic Quantification of Tumor-derived Extracellular Vesicles in Plasma MicrosamplesNIHNational Cancer Institute2021 to 2024$2,360,532September 25, 2020August 31, 2025HU, TONY Y.reporter.nih.gov
New Therapuetics for Pancreatic CancerNIHNational Cancer Institute2022 to 2025$2,353,939May 3, 2022April 30, 2027FERNANDEZ-ZAPICO, MARTIN ERNESTOreporter.nih.gov
Advancing Precision Oncology in a Humanized, Fully Autologous Mouse ModelNIHNational Cancer Institute2021 to 2024$2,342,069March 1, 2020February 28, 2026FIELDS, RYAN Creporter.nih.gov
Chromatin Dynamics and Genome RegulationNIHNational Institute of General Medical Sciences2021 to 2025$2,335,578August 4, 2017May 31, 2027BANASZYNSKI, LAURAreporter.nih.gov
Targeting tumor architecture as a novel therapeutic strategy for pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,328,586February 1, 2021January 31, 2026LIGORIO, MATTEOreporter.nih.gov
DYSBIOTIC MICROBIOME IN PANCREATITIS, DIABETES, AND PANCREATIC CANCERNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,315,838September 28, 2015June 30, 2025FISHER, WILLIAM Ereporter.nih.gov
Cancer under pressure: Mechanisms of adaptation to compressive stressNIHNational Cancer Institute2021 to 2025$2,297,421June 1, 2019May 31, 2026HOLT, LIAM Jreporter.nih.gov
Development of irreversible electroporation-based rational combinations to potentiate the activity of cancer immunotherapy against pancreatic ductal adenocarcinomaNIHNational Cancer Institute2022 to 2025$2,296,728February 1, 2022January 31, 2027LI, CHUNreporter.nih.gov
Interrogation of the Impact of Selection on the Evolution of Human Pancreatic Cancer Precursor LesionsNIHNational Cancer Institute2022 to 2025$2,293,529September 15, 2022August 31, 2027WOOD, LAURA DELONGreporter.nih.gov
Novel CAR T cell engineering strategies for effective eradication of solid and liquid tumorsNIHNational Cancer Institute2021 to 2025$2,291,623September 20, 2019May 31, 2030MAUS, MARCELA VALDERRAMAreporter.nih.gov
Regulation of Nutrient Stress-Induced Macropinocytosis in Pancreatic Ductal AdenocarcinomaNIHNational Cancer Institute2021 to 2025$2,288,727July 1, 2016August 31, 2026COMMISSO, COSIMOreporter.nih.gov
Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,285,106December 8, 2021November 30, 2025SERGIENKO, EDUARD A.reporter.nih.gov
Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological responseNIHNational Cancer Institute2021 to 2025$2,282,334September 13, 2017November 30, 2027JOHNSON, JEREMIAH ALLENreporter.nih.gov
Targeting Stromal Influences on BCKA Addiction in PDAC TumorsNIHNational Cancer Institute2022 to 2025$2,269,440March 1, 2022February 28, 2027NAGRATH, DEEPAKreporter.nih.gov
AGR2-superantigen vaccine conjugate for the treatment of pancreaticductal adenocarcinomaNIHNational Cancer Institute2023 to 2025$2,268,465May 17, 2022July 31, 2026ROBINSON, REEDER MCNEILreporter.nih.gov
Validation of novel imaging and molecular tests for early detection of pancreatic cancer through risk-stratified community engagement programsNIHNational Cancer Institute2023 to 2025$2,262,413May 15, 2023April 30, 2028SEARS, ROSALIE Creporter.nih.gov
Development of a precision medicine platform for circadian based therapeutics in pancreatic cancerNIHNational Cancer Institute2024 to 2025$2,259,957September 1, 2024August 31, 2027BISHEHSARI, FARAZreporter.nih.gov
Mitochondrial heterogeneity as the origin of chemoresistance in pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,258,753April 1, 2021March 31, 2026VIALE, ANDREAreporter.nih.gov
Targeting Epigenomic Regulators at the Replication Fork in PDACNIHNational Cancer Institute2021 to 2025$2,253,755April 1, 2021March 31, 2027LOMBERK, GWENreporter.nih.gov
Targeting MTOR signaling in pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,238,712May 4, 2022April 30, 2027LEWIS, BRIAN Creporter.nih.gov
Combining Irreversible Electroporation with Immunotherapy for the Systemic Treatment of Pancreatic CancerNIHNational Cancer Institute2021 to 2025$2,232,512January 20, 2021December 31, 2025WHITE, REBEKAHreporter.nih.gov
Novel Nanomedicine-Based Therapeutic Approach For Treatment of Cancer CachexiaNIHNational Cancer Institute2021 to 2025$2,226,892May 1, 2024April 30, 2027TARATULA, OLEHreporter.nih.gov
The Ohio State University Chronic Pancreatitis Diabetes Pancreas Cancer (CPDPC) Clinical CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,226,595September 28, 2015June 30, 2025HART, PHILIP A.reporter.nih.gov
Rational in situ programming of cancer vaccine-responding T-cell clonesNIHNational Cancer Institute2021 to 2025$2,219,015July 1, 2021June 30, 2026STEPHAN, MATTHIASreporter.nih.gov
Modulation of Tumor Microenvironment for Improved Therapy of Pancreatic CancerNIHNational Cancer Institute2021 to 2024$2,211,941December 20, 2019May 31, 2025JAIN, MANEESHreporter.nih.gov
Dissecting the Source and Mechanisms of IL-17-Mediated Modulation of Pancreatic TumorigenesisNIHNational Cancer Institute2021 to 2025$2,204,373September 18, 2020August 31, 2027MCALLISTER, FLORENCIAreporter.nih.gov
Developing translationally-relevant genetically engineered mouse models of lung adenocarcinoma for investigations in cancer immunologyNIHNational Cancer Institute2021 to 2024$2,192,022April 1, 2020March 31, 2025JOSHI, NIKHILreporter.nih.gov
Role of type 2 immune response in pancreatic cancer tumorigenesisNIHNational Cancer Institute2021 to 2025$2,165,563July 15, 2021June 30, 2026DEY, PRASENJITreporter.nih.gov
Mechanisms of p53 Engagement and Action at the Benign-to-Malignant Transition in Sporadic TumorigenesisNIHNational Cancer Institute2023 to 2025$2,159,255July 3, 2023June 30, 2028LOWE, SCOTT W.reporter.nih.gov
PRSS1 Mutation and Pancreatic Cancer TumorigenesisNIHNational Cancer Institute2021 to 2025$2,153,348September 1, 2025August 31, 2027JI, BAOANreporter.nih.gov
Intravascular Delivery of Nanoclusters for Treatment of Deep-Seated Cancers with Magnetic HyperthermiaNIHNational Cancer Institute2021 to 2024$2,150,799March 1, 2020February 28, 2026TARATULA, OLEHreporter.nih.gov
Investigation of novel signaling protein in 3D and in vivo PDAC models using second generation Ref-1 inhibitorsNIHNational Cancer Institute2021 to 2025$2,142,929June 1, 2021May 31, 2027FISHEL, MELISSA L.reporter.nih.gov
Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancersNIHNational Cancer Institute2021 to 2025$2,137,708July 1, 2025June 30, 2027BRYANT, KIRSTEN Lreporter.nih.gov
Leveraging deep learning for markerless motion management in radiation therapyNIHNational Cancer Institute2021 to 2025$2,135,070April 1, 2021March 31, 2026XING, LEIreporter.nih.gov
Identification of key tumor cell-released factors that induce cachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,132,780July 1, 2013March 31, 2026LI, YI-PINGreporter.nih.gov
PQ6: Therapeutic approaches for autonomic and neuroendocrine dysfunction in cancer cachexiaNIHNational Cancer Institute2021 to 2025$2,124,924September 10, 2021August 31, 2026GROSSBERG, AARONreporter.nih.gov
Development of a Novel Resolvin-Based Therapy for Treatment of Pancreatic CancerNIHNational Cancer Institute2023 to 2025$2,123,607June 2, 2023May 31, 2027PARKINSON, JOHNreporter.nih.gov
Mechanisms of immunotherapy response and resistance in pancreatic ductal adenocarcinomaNIHNational Cancer Institute2021 to 2025$2,120,190March 1, 2021February 28, 2027STROMNES, INGUNN MARGARETEreporter.nih.gov
Function of IL35+ B cells in pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,097,098April 1, 2024March 31, 2027PYLAYEVA-GUPTA, YULIYAreporter.nih.gov
Defining metabolic adaptations within the PDAC "arid" tumor microenvironmentNIHNational Cancer Institute2022 to 2025$2,093,761May 1, 2021April 30, 2026DANG, CHI V.reporter.nih.gov
Multi-Ancestry Mapping of Pancreatic Cancer Susceptibility LociNIHNational Cancer Institute2021 to 2025$2,089,324May 5, 2020January 31, 2027KLEIN, ALISON Preporter.nih.gov
The Oral Mycobiome and Risk of Pancreatic CancerNIHNational Cancer Institute2021 to 2024$2,088,042September 23, 2021August 31, 2025AHN, JIYOUNGreporter.nih.gov
Targeting aberrant enhancer landscapes in pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,086,637July 2, 2019August 31, 2029VAKOC, CHRISTOPHERreporter.nih.gov
Targeting cysteine import to induce ferroptotic cell death in pancreatic cancerNIHNational Cancer Institute2021 to 2025$2,084,103March 8, 2017February 28, 2027OLIVE, KENNETH P.reporter.nih.gov
Developing a Translation Pipeline for VHL Mutant MalignanciesNIHNational Cancer Institute2021 to 2025$2,084,051April 1, 2019March 31, 2028MCDERMOTT, DAVIDreporter.nih.gov
Use of a Nano-Enabled Platform for Pancreatic Cancer ImmunotherapyNIHNational Cancer Institute2021 to 2024$2,074,477July 1, 2020June 30, 2025NEL, ANDRE ELIASreporter.nih.gov
Targeting Focal Adhesion Kinase to Improve RT-inducted Tumor ImmunityNIHNational Cancer Institute2021 to 2024$2,068,221April 14, 2020March 31, 2026DENARDO, DAVID Greporter.nih.gov
Role of Altered Nutrient Metabolism in Pancreatic CancerNIHNational Cancer Institute2022 to 2025$2,061,446April 1, 2022March 31, 2027KALAANY, NADA Y.reporter.nih.gov
Mechanistic Understanding for the Role of Lin28b in Pancreatic Cancer ProgressionNIHNational Cancer Institute2021 to 2023$2,060,694February 19, 2019January 31, 2024MOSTOSLAVSKY, RAULreporter.nih.gov
CAR T cells targeting mesothelin and secreting bispecific antibodies targeting fibroblasts in pancreatic cancerNIHNational Cancer Institute2025$2,054,733September 1, 2025August 31, 2028MAUS, MARCELA VALDERRAMAreporter.nih.gov
Novel Therapy to Inhibit IPMN ProgressionNIHNational Cancer Institute2022 to 2024$2,052,249June 8, 2022May 31, 2027MALAFA, MOKENGE P.reporter.nih.gov
Dissecting the role of Notch signaling in the pancreatic cancer microenvironment.NIHNational Cancer Institute2022 to 2025$2,050,796April 1, 2022March 31, 2027PASCA DI MAGLIANO, MARINAreporter.nih.gov
Dietary fatty acids drive pancreatic cancer developmentNIHNational Cancer Institute2023 to 2025$2,048,497July 10, 2023June 30, 2028MUZUMDAR, MANDAR DEEPAKreporter.nih.gov
Preclinical Development of ACXT-3102 for the Treatment of Pancreatic Adenocarcinoma (PDAC)NIHNational Cancer Institute2021 to 2022$2,033,915September 23, 2019July 31, 2025KELLER, BRADLEY T.reporter.nih.gov
Angiopoietin-2/Tie2 signaling regulation of liver metastasis in pancreatic neuroendocrine tumorsNIHNational Cancer Institute2022 to 2025$2,033,782July 12, 2022June 30, 2027KIM, MINAHreporter.nih.gov
U-01 CONSORTIUM FOR THE STUDY OF CHRONIC PANCREATITIS,DIABETES AND PANCREATIC CANCER CLINICAL CENTERSNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,029,822September 28, 2015June 30, 2025FORSMARK, CHRISTOPHER Ereporter.nih.gov
POLQ Synthetic Lethality in HR-Deficient Pancreatic AdenocarcinomaNIHNational Cancer Institute2021 to 2023$2,012,904July 16, 2020March 15, 2024SIMEONE, DIANE Mreporter.nih.gov
Enhancing engineered T cell therapeutic efficacy for the treatment of pancreatic ductal adenocarcinomaNIHNational Cancer Institute2021 to 2025$2,010,185September 16, 2021July 31, 2027STROMNES, INGUNN MARGARETEreporter.nih.gov
Controlling Tumor Immune Escape in Pancreatic Cancer using a Dual T Cell Product StrategyNIHNational Cancer Institute2024 to 2025$1,999,145June 14, 2024May 31, 2026VERA, JUAN FERNANDOreporter.nih.gov
Development of novel therapeutics for cancer cachexiaNIHNational Cancer Institute2023 to 2024$1,987,656April 1, 2023March 31, 2026EBERT, SCOTT MATTHEWreporter.nih.gov
Novobiocin-mediated polymerase theta inhibition in homologous recombination repair-deficient cancersNIHNational Cancer Institute2022 to 2025$1,976,994September 1, 2022August 31, 2027SHAPIRO, GEOFFREY I.reporter.nih.gov
Stromal and vascular inputs into pancreatic cancer tumor neighborhoodsNIHNational Cancer Institute2023 to 2025$1,974,763July 15, 2023June 30, 2028STANGER, BEN Zreporter.nih.gov
Cellular phenotypic heterogeneity and resistance to radiotherapy in pancreatic adenocarcinomaNIHOffice of the Director, National Institutes of Health2021 to 2025$1,968,750September 22, 2021August 31, 2026PITTER, KENNETH Lreporter.nih.gov
Potentiating a systemic antitumor response by interstitial localized ablative immunotherapy to synergize with immune checkpoint therapy for metastatic pancreatic tumorsNIHNational Cancer Institute2022 to 2025$1,966,506April 1, 2022March 31, 2027CHEN, WEI R.reporter.nih.gov
Role of extracellular matrix proteins and tumor stroma in DNA repair and cancer progressionNIHNational Cancer Institute2021 to 2025$1,963,134February 1, 2021January 31, 2026MURANEN, TARU ELIISAreporter.nih.gov
Non-invasive staging of Metastasis by Precision MRINIHNational Cancer Institute2022 to 2023$1,954,220September 23, 2022April 30, 2025XU, YITINGreporter.nih.gov
New Ways of Targeting K-RasNIHNational Cancer Institute2021 to 2022$1,950,085April 1, 2016March 31, 2023MCCORMICK, FRANK PATRICKreporter.nih.gov
A single-arm phase II study to evaluate the safety and efficacy of combination systematic chemotherapy and multiple rounds of endoscopic ultrasound-guided radiofrequency ablation in pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,948,805July 1, 2023June 30, 2028THOSANI, NIRAVreporter.nih.gov
Endoscopic Fine-Needle Light Scattering Spectroscopy for Pancreatic Cyst Diagnosis and Evaluation of Malignant PotentialNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$1,942,727September 30, 2017April 30, 2028PERELMAN, LEV Treporter.nih.gov
Development of a DCLK1 siRNA Nanoparticle as Targeted Therapy to Treat Pancreatic CancerNIHNational Cancer Institute2021 to 2022$1,935,472August 22, 2018July 31, 2024DE OLIVEIRA, ELISEU O.reporter.nih.gov
Inhibitors of Oxidative Protein Folding For The Treatment of CancerNIHNational Cancer Institute2021 to 2024$1,933,012July 1, 2020June 30, 2026DOLLOFF, NATHAN G.reporter.nih.gov
Disparities in access to and outcomes of cancer surgery for rural Medicare patientsNIHNational Cancer Institute2021 to 2023$1,929,880March 1, 2020February 28, 2025TOSTESON, ANNA N. A.reporter.nih.gov
Co-targeting BET Bromodomain Proteins and MNK Kinases in Pancreatic CancerNIHNational Cancer Institute2022 to 2025$1,927,720April 1, 2022March 31, 2027MUNSHI, HIDAYATULLAH G.reporter.nih.gov
Development and implementation of multiplex methods to understand the biology and heterogeneity of patient-derived cancer modelsNIHNational Cancer Institute2021 to 2022$1,926,843June 15, 2020May 31, 2023HAHN, WILLIAM C.reporter.nih.gov
Novel approaches to improve prediction of cancer-associated thrombosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,925,190August 1, 2018July 31, 2025MCCRAE, KEITH R.reporter.nih.gov
Structure-based inhibition of chemokine signaling in the inflamed pancreasNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,924,560April 20, 2023December 31, 2026VOLKMAN, BRIAN Freporter.nih.gov
PQ6: Lipocalin-2 as a therapeutic target for prevention of cancer cachexiaNIHNational Cancer Institute2021 to 2025$1,918,262April 1, 2021March 31, 2026ZIMMERS, TERESA Areporter.nih.gov
Mechanisms governing metastatic dormancy and reactivationNIHNational Cancer Institute2021 to 2022$1,915,493August 1, 2016July 31, 2023GIANCOTTI, FILIPPO Greporter.nih.gov
Ultra-high content analyses of circulating and solid tumor cells: A diagnostic reference system for disease burdenNIHNational Cancer Institute2021 to 2023$1,913,568August 16, 2021August 31, 2025NEDERLOF, MICHELreporter.nih.gov
Rapid and flexible precision oncology mouse models of epithelial malignancies epithelial malignanciesNIHNational Cancer Institute2021 to 2024$1,908,434January 1, 2020December 31, 2024LOWE, SCOTT W.reporter.nih.gov
Machine learning accelerated on-line adaptive replanningNIHNational Cancer Institute2021 to 2024$1,907,890April 1, 2020March 31, 2026PAULSON, ERIC Sreporter.nih.gov
Discovery of Novel Inhibitors Targeting trans-Golgi Network Acidification in Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,905,554March 22, 2023February 28, 2027COMMISSO, COSIMOreporter.nih.gov
Cyst-X: Interpretable Deep Learning Based Risk Stratification of Pancreatic Cystic TumorsNIHNational Cancer Institute2021 to 2024$1,899,993March 1, 2020February 28, 2025BAGCI, ULASreporter.nih.gov
Subpopulations of Pancreatic Cancer Cells Defined by Glycan MarkersNIHNational Cancer Institute2021 to 2023$1,889,934April 18, 2019March 31, 2025HAAB, BRIAN B.reporter.nih.gov
Mechanisms of myeloid cell driven pancreatic plasticity and carcinogenesisNIHNational Cancer Institute2023 to 2025$1,888,752February 1, 2023January 31, 2028PASCA DI MAGLIANO, MARINAreporter.nih.gov
Breaking down tumor immune privilege through targeted hypoxia reductionNIHNational Cancer Institute2021 to 2024$1,883,414July 1, 2020June 30, 2025CURRAN, MICHAEL A.reporter.nih.gov
Application of 4D proteomics and super-resolution microscopy in extracellular vesicle and particle-borne biomarker discovery for early pancreatic cancer detectionNIHNational Cancer Institute2021 to 2025$1,860,142July 15, 2017August 31, 2028LYDEN, DAVID CHARLESreporter.nih.gov
Preclinical Development of First-in-Class NDUFS7 Antagonists for the Treatment of Pancreatic CancerNIHNational Cancer Institute2022 to 2025$1,858,436August 16, 2022July 31, 2027NEAMATI, NOURIreporter.nih.gov
Vascularized tumor explants for drug testingNIHNational Cancer Institute2021 to 2025$1,856,363July 1, 2021June 30, 2026MUNN, LANCE L.reporter.nih.gov
The Complement System and Cancer CachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,856,131August 1, 2022July 31, 2027JUDGE, ANDREW ROBERTreporter.nih.gov
Distinguishing Pancreatic Cancer from Benign Pancreatic Disease using Nanoparticle-based BiomarkersNIHNational Cancer Institute2022 to 2025$1,853,683January 1, 2022December 31, 2026IBSEN, STUART DUNCANreporter.nih.gov
NF-kB Regulation of the Muscle Microenvironment in Cancer CachexiaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,849,772February 26, 2020June 30, 2025GUTTRIDGE, DENIS Creporter.nih.gov
Metaplastic Tuft Cells in Pancreatic CancerNIHNational Cancer Institute2021 to 2024$1,848,585March 9, 2020February 28, 2025CRAWFORD, HOWARD C.reporter.nih.gov
Targeting the autophagy-lysosome system to block pancreatic cancerNIHNational Cancer Institute2021 to 2025$1,842,352April 1, 2021March 31, 2026PERERA, RUSHIKA MIRIAMreporter.nih.gov
Mechanistic investigations of microbiome-driven aryl hydrocarbon receptor activity and macrophage function in pancreatic cancer.NIHNational Cancer Institute2021 to 2025$1,832,774May 1, 2021April 30, 2026MCGAHA, TRACY Lreporter.nih.gov
The Role of HIF2 in Pancreatic Ductal AdenocarcinomaNIHNational Cancer Institute2023 to 2025$1,829,056January 1, 2023December 31, 2027KOONG, ALBERTreporter.nih.gov
Understanding Efficacy and Fe(II)-Promoted Activation of 1,2,4-Trioxolanes in CancerNIHNational Cancer Institute2021 to 2023$1,828,756April 1, 2021January 1, 2024COLLISSON, ERICreporter.nih.gov
Intratumoral Metabolic Crosstalk Promotes Therapeutic Resistance in Pancreatic CancerNIHNational Cancer Institute2021 to 2025$1,826,752December 1, 2019April 30, 2027LYSSIOTIS, COSTAS ANDREASreporter.nih.gov
Defining epigenetic signaling to reshape pancreatic tumor microenvironmentNIHNational Cancer Institute2022 to 2025$1,825,475August 1, 2022July 31, 2027SHI, JIAQIreporter.nih.gov
TGX-1214 - Combination Strategy for the Treatment of Advanced Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,822,280February 1, 2023January 31, 2028MACKENZIE, GERARDO GUILLERMOreporter.nih.gov
Optimizing Pancreatic Cancer Management with Next Generation Imaging and Liquid BiopsyNIHNational Cancer Institute2021 to 2023$1,819,390April 1, 2021January 1, 2024COLLISSON, ERICreporter.nih.gov
Branched chain amino acids and pancreatic cancerNIHNational Cancer Institute2021 to 2024$1,818,769July 1, 2020June 30, 2025WELLEN, KATHRYN ELAINEreporter.nih.gov
Universal Internal Standard for Reproducible Accurate Quantification of Exosome Protein MarkersNIHNational Cancer Institute2022 to 2025$1,817,095January 14, 2022December 31, 2026LUBMAN, DAVID M.reporter.nih.gov
Integrated Informatic and Experimental Evaluations of Cancer ChronotherapyNIHNational Cancer Institute2021 to 2023$1,815,681April 3, 2019March 31, 2025ANAFI, RON C.reporter.nih.gov
Studying the role of eIF4A in Pancreatic CancerNIHNational Cancer Institute2022 to 2025$1,814,961July 1, 2022June 30, 2027CHIO, CHRISTINE IOK INreporter.nih.gov
Dissecting new mechanisms of lysosome quality control in health and diseaseNIHNational Cancer Institute2021 to 2025$1,813,908April 1, 2021March 31, 2026PERERA, RUSHIKA MIRIAMreporter.nih.gov
Comparative analysis between patient-derived models of pancreatic ductal adenocarcinomas and matched tumor specimensNIHNational Cancer Institute2021 to 2023$1,808,050September 12, 2019August 31, 2024SEARS, ROSALIE Creporter.nih.gov
Molecular Basis of ME2-mediated Tumor Suppression in Pancreatic CancerNIHNational Cancer Institute2022 to 2025$1,803,627August 1, 2022July 31, 2027SINGH, PANKAJ KUMARreporter.nih.gov
Microbial- based targeting of major extracellular matrix components for improved therapy of pancreatic cancerNIHNational Cancer Institute2022 to 2025$1,800,436September 9, 2022August 31, 2027MANUEL, EDWINreporter.nih.gov
The CCK-B receptor signaling pathway as a driver of pancreatic cellular plasticity and carcinogenesisNIHNational Cancer Institute2023 to 2025$1,799,961March 1, 2023February 29, 2028SMITH, JILL Preporter.nih.gov
A novel highly stable pancreatic enzyme replacement therapy to improve outcomes for patients with pancreatic insufficiency.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022$1,796,643August 5, 2022July 31, 2023GALLOTTO, ROBERTreporter.nih.gov
Harnessing TNFa Signaling To Improve Therapeutic Response In Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,793,296April 1, 2023March 31, 2028LIM, KIAN Hreporter.nih.gov
Mechanistic Pharmacokinetics and PharmacodynamicsNIHNational Institute of General Medical Sciences2021 to 2023$1,792,910May 1, 2019April 30, 2025JUSKO, WILLIAM J.reporter.nih.gov
Multifunctional Biodegradable Zwitterionic Polymer-Drug Conjugates for Multidrug Co-DeliveryNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,789,662April 1, 2023March 31, 2027CHENG, CHONGreporter.nih.gov
Irreversible Electroporation (IRE) Combined with CD40 Agonism as In Situ Vaccine Therapy for Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,788,109September 19, 2023August 31, 2028WHITE, REBEKAHreporter.nih.gov
Molecular Imaging Probe(s) for Optical Surgical Navigation of Pancreatic CancerNIHNational Cancer Institute2022 to 2025$1,782,697February 1, 2022January 31, 2027BOUVET, MICHAELreporter.nih.gov
Translational Development of a Targeted and Stroma-penetrating Nanoparticle Drug for Pancreatic Cancer TherapyNIHNational Cancer Institute2022 to 2023$1,776,357September 19, 2019August 31, 2025ZHU, LEIreporter.nih.gov
Receptor-Targeted Fluorescence-Guided Surgery in Pancreatic Neuroendocrine TumorsNIHNational Cancer Institute2022 to 2025$1,775,312July 1, 2022February 28, 2028AZHDARINIA, ALIreporter.nih.gov
Targeting the DNA damage response in combination with radiation to induce innate immunity and improve immunotherapy efficacy in pancreatic cancerNIHNational Cancer Institute2021 to 2024$1,769,224March 1, 2020February 28, 2026MORGAN, MEREDITH Areporter.nih.gov
Preventing an Incurable Disease: The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)NIHNational Cancer Institute2021 to 2023$1,758,921September 20, 2019August 31, 2025ALLEN, PETER Jreporter.nih.gov
Investigating GLI transcription factors as regulators of the pancreatic cancer microenvironmentNIHNational Cancer Institute2023 to 2025$1,754,882May 1, 2023April 30, 2028ALLEN, BENJAMINreporter.nih.gov
Nanomedicine of Hedgehog and AKT/ERK Dual Inhibitors for Pancreatic CancerNIHNational Cancer Institute2022 to 2025$1,750,136January 25, 2022December 31, 2026MAHATO, RAM I.reporter.nih.gov
Engrailed-1 and Epigenetic Vulnerabilities in Metastatic Pancreatic CancerNIHNational Cancer Institute2021 to 2025$1,741,851March 8, 2021February 28, 2026HWANG, CHANG-ILreporter.nih.gov
Exploiting Integrin Signaling to Overcome Resistance to ImmunotherapyNIHNational Cancer Institute2021 to 2024$1,738,599December 1, 2019November 30, 2025DENARDO, DAVID Greporter.nih.gov
Targeting Acquired Resistance in KRAS Driven CancersNIHNational Cancer Institute2022 to 2025$1,736,422August 12, 2022July 31, 2027YAO, WANTONGreporter.nih.gov
OVERCOMING STROMAL BARRIERS TO THERAPEUTICS IN PANCREAS CANCERNIHNational Cancer Institute2022 to 2025$1,733,335August 11, 2022May 31, 2027HINGORANI, SUNIL Rreporter.nih.gov
The Impact of Metastatic Site On Dendritic Cell-Driven Tumor ImmunityNIHNational Cancer Institute2023 to 2025$1,732,087September 19, 2023August 31, 2028DENARDO, DAVID Greporter.nih.gov
Develop Conditionally Armored CAR Macrophage Therapy for Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,725,994September 5, 2023July 31, 2028HOU, PINGPINGreporter.nih.gov
Elucidating the Immune Suppressive Mechanism of SIGLEC-15 in the Tumor MicroenvironmentNIHNational Cancer Institute2023 to 2025$1,723,069December 1, 2022November 30, 2027WANG, JUNreporter.nih.gov
Biomarkers and mechanisms in cancer associated thrombosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,704,665August 1, 2018July 31, 2024FLAUMENHAFT, ROBERT Creporter.nih.gov
Targeting cell regulatory states to complement MEK/autophagy inhibition in pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,698,952December 19, 2022November 30, 2027OLIVE, KENNETH P.reporter.nih.gov
Generation of antibody-drug conjugates by proximity-based sortase-mediated ligationNIHNational Cancer Institute2021 to 2022$1,692,174August 1, 2017June 30, 2024YU, FEIFANreporter.nih.gov
Use of Circulating MicroRNAs for Early Detection and Risk Assessment for Pancreatic CancerNIHNational Cancer Institute2021 to 2023$1,681,156January 1, 2019December 31, 2025SHU, XIAO-OUreporter.nih.gov
Targeting the Plasminogen Activation System to Limit Pancreatic Cancer Progression and Associated ThrombosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,678,924August 1, 2018July 31, 2025FLICK, MATTHEW J.reporter.nih.gov
CSHL-JAX Patient-Derived Models of Pancreatic Cancer as Systems for Investigating Tumor HeterogeneityNIHNational Cancer Institute2021 to 2022$1,668,786March 6, 2018February 29, 2024TUVESON, DAVID Areporter.nih.gov
Deploying Histotripsy Based Tumor Ablation Strategies to Treat Pancreatic CancerNIHNational Cancer Institute2022 to 2025$1,661,349May 1, 2022April 30, 2027ALLEN, IRVING Creporter.nih.gov
Exploring the epigenetic control of pancreatic cancer subtypesNIHNational Cancer Institute2021 to 2025$1,661,284July 1, 2024June 30, 2027KUGEL, SITAreporter.nih.gov
Mechanisms of response and resistance to KRAS inhibition in pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,657,228January 1, 2023December 31, 2027AGUIRRE, ANDREW JAMESreporter.nih.gov
Epigenomic Regulation in Pancreatic Cell GrowthNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,650,291September 25, 1998December 31, 2024URRUTIA, RAUL A.reporter.nih.gov
Using Markers to Improve Pancreatic Cancer ScreeningNIHNational Cancer Institute2021 to 2024$1,630,491July 1, 2013June 30, 2025GOGGINS, MICHAEL G.reporter.nih.gov
The NYU Women's Health StudyNIHNational Cancer Institute2021 to 2023$1,621,115May 1, 2015April 30, 2025CHEN, YUreporter.nih.gov
Using microvolumetric cyst fluid proteolysis for early detection of pancreatic cancerNIHNational Cancer Institute2024 to 2025$1,621,080June 1, 2024May 31, 2029KIRKWOOD, KIMBERLY SAUNDERSreporter.nih.gov
The function of the PRMT5 methylosome in MTAP deleted cancersNIHNational Cancer Institute2021 to 2025$1,621,014July 1, 2019June 30, 2030SELLERS, WILLIAM Rreporter.nih.gov
Fatty acid signaling in the pancreatic tumor microenvironmentNIHNational Cancer Institute2022 to 2025$1,614,268July 12, 2018June 30, 2028SHERMAN, MARA H.reporter.nih.gov
Optimization of High Frequency Irreversible Electroporation (H-FIRE) for tumor ablation and immune system activation in pancreatic cancer applicationsNIHNational Cancer Institute2023 to 2025$1,612,386May 10, 2023March 31, 2028ALLEN, IRVING Creporter.nih.gov
Stimuli-responsive mucin1-specific nanoparticles for efficacious combinatorial chemotherapy of pancreatic ductal adenocarcinomaNIHNational Cancer Institute2022 to 2025$1,611,629August 1, 2022July 31, 2027VIVERO-ESCOTO, JUAN LUISreporter.nih.gov
Novel CCR2 PET for Pancreatic Cancer Imaging and Prediction of Response to Standard and CCR2-Targeted TherapyNIHNational Cancer Institute2021 to 2024$1,610,237January 1, 2019June 30, 2025DEHDASHTI, FARROKHreporter.nih.gov
Repolarizing the Tumor and Metastatic Microenvironments to Treat Patients with Pancreatic CancerNIHNational Cancer Institute2021 to 2025$1,605,800August 2, 2021August 31, 2025GERBER, SCOTT ANDREWreporter.nih.gov
Targeting pancreatic cancer's metabolic addiction to HuRNIHNational Cancer Institute2021 to 2024$1,596,393September 1, 2023August 31, 2025WINTER, JORDAN Mreporter.nih.gov
Diet-mediated regulation of fatty acid saturation impacts cancer progression and therapy responses.NIHNational Cancer Institute2024 to 2025$1,593,596April 1, 2024March 31, 2029LIEN, EVAN CHENreporter.nih.gov
Divergent Roles of MerTK,Tyro3, and Axl in Pancreatic Cancer and MetastasisNIHNational Cancer Institute2023 to 2025$1,584,951December 1, 2022November 30, 2027EARP, H. SHELTONreporter.nih.gov
Development of Microbial-Based Therapies to Suppress Macropinocytosis in Kras-Driven CancersNIHNational Cancer Institute2022 to 2025$1,582,219July 1, 2022June 30, 2027MANUEL, EDWINreporter.nih.gov
Inhibitors of the G protein GNAS which drives pancreatic tumorigenesisNIHNational Cancer Institute2021 to 2024$1,578,514March 1, 2020February 28, 2026SHOKAT, KEVAN M.reporter.nih.gov
Lineage specifiers governing pancreatic cancer growth and molecular subtypeNIHNational Cancer Institute2021 to 2024$1,576,922June 1, 2020May 31, 2026SNYDER, ERIC LEEreporter.nih.gov
Stromal metabolism promotes therapeutic resistance in pancreatic cancerNIHNational Cancer Institute2021 to 2024$1,574,573April 1, 2020June 30, 2025LYSSIOTIS, COSTAS ANDREASreporter.nih.gov
Multi-site Gastrointestinal Cancer Detection by Stool DNA MethylationNIHNational Cancer Institute2021 to 2024$1,573,848April 1, 2023March 31, 2025KISIEL, JOHNreporter.nih.gov
Metabolic flux analysis and PDX models to understand therapeutic vulnerabilities following inhibition of Ref-1 redox signaling in pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,572,962August 1, 2023July 31, 2028KELLEY, MARK R.reporter.nih.gov
Molecular Determinants and Therapeutic Consequences of Immune Heterogeneity in CancerNIHNational Cancer Institute2021 to 2022$1,568,117August 1, 2018July 31, 2023STANGER, BEN Zreporter.nih.gov
Use of BCL-xL Proteolysis targeting chimeras to treat pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,555,966September 1, 2019August 31, 2024ZHENG, GUANGRONGreporter.nih.gov
Discovering Spatial Mechanisms Regulating Metastatic Invadopodia in PDACNIHNational Cancer Institute2021 to 2024$1,544,346September 1, 2014May 31, 2025KLEMKE, RICHARD L.reporter.nih.gov
Metabolic changes accompanying durable, hypoxia-driven EMT in pancreas cancerNIHNational Cancer Institute2021 to 2023$1,534,092August 1, 2019July 31, 2025LAZZARA, MATTHEW Jreporter.nih.gov
Targeting metabolic stress to induce pancreatic tumor cell deathNIHNational Cancer Institute2021 to 2024$1,530,839July 1, 2020June 30, 2025LYSSIOTIS, COSTAS ANDREASreporter.nih.gov
Blood flow crosstalk between the endocrine and exocrine pancreasNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,526,940January 12, 2024December 31, 2028HARA, MANAMIreporter.nih.gov
Receptor for hyaluronan-mediated motility isoform B (RHAMM B) in Pancreatic Cancer MetastasisNIHNational Cancer Institute2022 to 2025$1,523,785August 1, 2022July 31, 2027DU, YI-CHIEH NANCYreporter.nih.gov
Targeting the liver for immunotherapy in pancreatic cancerNIHNational Cancer Institute2022 to 2025$1,516,736July 1, 2016November 30, 2026BEATTY, GREGORY Lreporter.nih.gov
Engineering Exosome for Pancreatic Cancer Targeting TherapiesNIHNational Cancer Institute2023 to 2025$1,510,439September 21, 2023August 31, 2028LIU, SHI-HEreporter.nih.gov
Ultrasenstive vesicle analysis in precancerous pancreatic neoplasm (IPMN)NIHNational Cancer Institute2021 to 2024$1,502,614June 1, 2020May 31, 2025WEISSLEDER, MD, PHD, RALPHreporter.nih.gov
Role of acetyl-CoA in linking cancer cell metabolism and epigeneticsNIHNational Cancer Institute2021 to 2024$1,496,909April 1, 2014March 31, 2025WELLEN, KATHRYN ELAINEreporter.nih.gov
Translating Intestinal Radioprotection by EGLN Inhibition to Improve Clinical Outcomes in Unresectable Pancreatic CancerNIHNational Cancer Institute2021 to 2023$1,496,161April 1, 2019March 31, 2024KOONG, ALBERTreporter.nih.gov
Impact of RB activation on the pancreatic cancer epigenome and tumor microenvironmentNIHNational Cancer Institute2023 to 2025$1,490,387July 7, 2023June 30, 2028WITKIEWICZ, AGNIESZKAreporter.nih.gov
Rewiring the myeloid cell response to adjuvants to improve tumor controlNIHNational Cancer Institute2021 to 2024$1,475,782December 2, 2019November 30, 2024GOUGH, MICHAEL JAMESreporter.nih.gov
Advancing Systematic Delivery of Oncolytic Adenovirus for Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,471,216July 1, 2023June 30, 2028DAVYDOVA, JULIAreporter.nih.gov
Investigating the molecular mechanisms of growth in GNAS mutant pancreatic cancer.NIHNational Cancer Institute2022 to 2025$1,456,361August 1, 2022July 31, 2027PATRA, KRUSHNA CHANDRAreporter.nih.gov
Targeting ribosome biogenesis and desmoplastic tumor microenvironment for the treatment of advanced pancreatic cancerNIHNational Institute of General Medical Sciences2021 to 2024$1,453,000May 17, 2021March 31, 2026HAFEEZ, BILAL BINreporter.nih.gov
Mechanisms and therapeutic targets of cancer metastasisNIHNational Cancer Institute2021 to 2024$1,452,754December 1, 2019November 30, 2025BEATTY, GREGORY Lreporter.nih.gov
Targeting the RNA Exosome for Cancer TherapeuticsNIHNational Cancer Institute2021 to 2023$1,448,637August 1, 2019July 31, 2024LJUNGMAN, MATSreporter.nih.gov
Identifying Molecular Drivers of Cellular Plasticity in Pancreatic CancerNIHNational Cancer Institute2021 to 2024$1,444,477September 3, 2020May 31, 2025PERERA, RUSHIKA MIRIAMreporter.nih.gov
3D carbon-nanotubes integrated microdevice for extracellular vesicle isolation and in situ sample preparation towards noninvasive pancreatic cancer diagnosisNIHNational Cancer Institute2021 to 2023$1,444,026August 10, 2019July 31, 2025ZHENG, SIYANGreporter.nih.gov
Role of ALK4 in Regulating Receptor Trafficking and Pancreatic Cancer BiologyNIHNational Cancer Institute2021 to 2023$1,442,081September 19, 2019August 31, 2025BLOBE, GERARD Creporter.nih.gov
Targeting HNF1A-mediated therapeutic resistance in pancreatic ductal adenocarcinomaNIHNational Cancer Institute2023 to 2025$1,441,755February 3, 2023December 31, 2027ABEL, ETHAN VINCENTreporter.nih.gov
NRF2-dependent redox signaling in pancreatic cancerNIHNational Cancer Institute2021 to 2024$1,439,223March 4, 2020February 28, 2025CHIO, CHRISTINE IOK INreporter.nih.gov
Optogenetic engineering of tumor topography in native tissue environmentsNIHNational Cancer Institute2023$1,437,358September 22, 2023August 31, 2026MADDIPATI, RAVIKANTHreporter.nih.gov
Combating Resistance of Pancreatic Cancer with a First-in-Class Dual Targeted PI3K/EGFR InhibitorNIHNational Cancer Institute2021 to 2023$1,433,852July 1, 2019June 30, 2025LEOPOLD, JUDITH Sreporter.nih.gov
Type I Interferon Pathway in Pancreatic AdenocarcinomaNIHNational Cancer Institute2021 to 2024$1,429,816April 1, 2020March 31, 2025FUCHS, SERGE Yreporter.nih.gov
Developing novel CAR T cell designs using combinatorial antigen detectionNIHNational Cancer Institute2021 to 2025$1,421,654April 1, 2021March 31, 2026ALLEN, GREG MANESSreporter.nih.gov
Disposable Perfusion Phantom for Accurate DCE-MRI Measurement of Pancreatic Cancer Therapy ResponseNIHNational Cancer Institute2021 to 2023$1,420,711August 1, 2019July 31, 2025EL-RAYES, BASSELreporter.nih.gov
The Evolution of PGD Addiction in Human Pancreatic CancerNIHNational Cancer Institute2021 to 2025$1,413,922December 1, 2018July 31, 2030MCDONALD, OLIVER GENEreporter.nih.gov
Origins and functions of pancreatic cancer-associated fibroblastsNIHNational Cancer Institute2022 to 2025$1,411,900January 1, 2023April 30, 2026SHERMAN, MARA H.reporter.nih.gov
Investigating hypoxia as a determinant of malignant fates in pancreas cancerNIHNational Cancer Institute2024 to 2025$1,409,244April 1, 2024March 31, 2029TAMMELA, TUOMASreporter.nih.gov
Preclinical development of a novel antibody conjugate for intraoperative detection of pancreatic cancerNIHNational Cancer Institute2022 to 2025$1,409,090March 4, 2022February 28, 2027MOHS, AARON M.reporter.nih.gov
Artificial Intelligence powered virtual digital twins to construct and validate AI automated tools for safer MR-guided adaptive RT of abdominal cancersNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,408,790September 1, 2023August 31, 2027TYAGI, NEELAMreporter.nih.gov
Stress adaptation in obesity-associated pancreatic cancerNIHNational Cancer Institute2021 to 2024$1,402,420July 1, 2023June 30, 2025GRABOCKA, ELDAreporter.nih.gov
Targeting PYK2 for the treatment of PDACNIHNational Cancer Institute2021 to 2024$1,399,757December 16, 2019November 30, 2025HU, JINGreporter.nih.gov
Highly Sensitive Detection of Occult Pancreatic Cancer Using Intraoperative Molecular ImagingNIHNational Cancer Institute2023 to 2025$1,396,340June 1, 2023May 31, 2028POULTSIDES, GEORGEreporter.nih.gov
Combination Therapy for Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,394,238April 1, 2023March 31, 2028LI, SONGreporter.nih.gov
Mechanisms of pancreatic cancer initiation and progression from normal human pancreatic tissueNIHNational Cancer Institute2021 to 2025$1,392,288March 1, 2020February 28, 2026WANG, PEIreporter.nih.gov
The Texas-Louisiana Alliance to Study Chronic Pancreatitis, Diabetes and Pancreatic CancerNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,390,069September 5, 2020June 30, 2025CHARI, SURESH T.reporter.nih.gov
A Fragment-Based Strategy for K-RAS Covalent InhibitorsNIHNational Cancer Institute2021 to 2023$1,388,881July 2, 2021March 1, 2024MEROUEH, SAMYreporter.nih.gov
Role of the METTL13 Lysine Methyltransferase in Signaling and CancerNIHNational Cancer Institute2021 to 2023$1,387,609March 1, 2019February 28, 2025GOZANI, OR P.reporter.nih.gov
IRAK4 AS A NOVEL IMMUNOTHERAPEUTIC TARGET IN PANCREATIC DUCTAL ADENOCARCINOMANIHNational Cancer Institute2021 to 2024$1,386,070February 1, 2023January 31, 2026LIM, KIAN Hreporter.nih.gov
Clinical Translation of Nuclear Export Inhibitor in Metastatic Pancreatic CancerNIHNational Cancer Institute2021 to 2024$1,383,672January 1, 2023December 31, 2024AZMI, ASFAR Sreporter.nih.gov
A novel therapy for pancreatic neuroendocrine tumorsNIHNational Cancer Institute2021 to 2024$1,382,791April 1, 2020March 31, 2026AZMI, ASFAR Sreporter.nih.gov
Pretargeted Clinical Imaging of CA19.9 in Pancreatic CancerNIHNational Cancer Institute2021 to 2022$1,377,564July 10, 2018June 30, 2024LEWIS, JASON S.reporter.nih.gov
Novel Strategies to Enhance Drug Delivery and Tumor Immunogenicity in Pancreatic CancerNIHNational Cancer Institute2024$1,377,000September 1, 2024August 31, 2027NAGALO, BOLNI MARIUSreporter.nih.gov
RBFOX2 deregulation promotes pancreatic cancer progression through alternative splicingNIHNational Cancer Institute2023 to 2025$1,370,948April 15, 2023March 31, 2028MANN, KAREN Mreporter.nih.gov
Development of a precision medicine platform for circadian based therapeutics in pancreatic cancerNIHNational Cancer Institute2022 to 2023$1,366,759September 21, 2022May 31, 2024BISHEHSARI, FARAZreporter.nih.gov
Defining the role of macropinocytosis in solid tumor growth and therapeutic resistanceNIHNational Cancer Institute2021 to 2024$1,362,712April 1, 2020March 31, 2026EDINGER, AIMEE Lreporter.nih.gov
Characterizing the role of MSRA in pancreatic tumorigenesisNIHNational Cancer Institute2023 to 2025$1,360,430May 17, 2023April 30, 2028CHIO, CHRISTINE IOK INreporter.nih.gov
Matricellular proteins of the CNN family as regulators of tumor-induced cachexiaNIHNational Cancer Institute2023 to 2025$1,357,279September 7, 2023August 31, 2028JUDGE, SARAH Mreporter.nih.gov
Optimizing anti-wild-type IDH1 therapy in pancreatic cancerNIHNational Cancer Institute2024 to 2025$1,351,989April 1, 2024March 31, 2029WINTER, JORDAN Mreporter.nih.gov
Metabolic regulation of immunosuppressive myeloid cells in the tumor microenvironment of pancreatic cancer.NIHNational Cancer Institute2024 to 2025$1,348,799April 2, 2024March 31, 2029ZHANG, YAQINGreporter.nih.gov
A Phase 1 Study of Patient-Derived Multi-Tumor Associated Antigen Specific T Cells (MT-601) Administered to Patients with Metastatic Pancreatic Cancer following frontline FOLFIRINOXNIHNational Cancer Institute2024 to 2025$1,348,550September 1, 2024August 31, 2027VERA, JUAN FERNANDOreporter.nih.gov
Mechanisms of JAG1-mediated immune suppression in the pancreatic cancer microenvironmentNIHNational Cancer Institute2024 to 2025$1,344,898July 1, 2024June 30, 2026ZHOU, LANreporter.nih.gov
Targeting novel therapeutic vulnerabilities in LKB1 mutant tumors.NIHNational Cancer Institute2021 to 2022$1,341,304July 11, 2018June 30, 2024EL-BARDEESY, NABEELreporter.nih.gov
Translating Hyperpolarized 13C MRI as a Novel Tool to Predict Treatment Response in Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,340,446January 1, 2024December 31, 2028GORDON, JEREMY WILLIAMreporter.nih.gov
STAT3 is a Critical Regulator of Tumor Cell PlasticityNIHNational Cancer Institute2021 to 2023$1,328,239July 1, 2019June 30, 2025REICH MARSHALL, NANCY C.reporter.nih.gov
Targeted inhibition in stromal TGFβ activity in pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,328,165July 6, 2020June 30, 2025BREKKEN, ROLF Areporter.nih.gov
Mutant KRAS targeted vaccines for the interception of pancreatic cancer developmentNIHNational Cancer Institute2024 to 2025$1,318,180September 1, 2024August 31, 2029ZAIDI, NEEHAreporter.nih.gov
Understanding efficacy and FE(II)-Promoted Activation of 1,2,4-Trioxolanes in cancerNIHNational Cancer Institute2024 to 2025$1,316,613April 1, 2021May 31, 2027COLLISSON, ERICreporter.nih.gov
Phosphatidylserine acyl chain remodeling regulates KRAS spatial distribution and function on the plasma membrane.NIHNational Institute of General Medical Sciences2021 to 2024$1,310,400May 1, 2021September 30, 2025ZHOU, YONGreporter.nih.gov
PPARD hyperactivation promotes pancreatic intraepithelial neoplasia progression into pancreatic ductal adenocarcinomaNIHNational Cancer Institute2024 to 2025$1,308,791February 15, 2024January 31, 2029SHUREIQI, IMADreporter.nih.gov
Targeting Transglutaminase 2 in cancer cachexiaNIHNational Cancer Institute2021 to 2024$1,307,284July 1, 2020June 30, 2025ATFI, AZEDDINEreporter.nih.gov
Causes and Consequences of Adenosine Signaling in Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,307,077June 26, 2024May 31, 2029DONAHUE, TIMOTHY Rreporter.nih.gov
A SYNTHETIC BIOMARKER TO UNIVERSALLY ASSESS THE RELATIVE CONTRIBUTION OF HEATHY AND CANCEROUS TISSUE TO CIRCULATING EV POOLNIHNational Cancer Institute2023 to 2025$1,300,736December 15, 2022November 30, 2027COCUCCI, EMANUELEreporter.nih.gov
Understanding Pancreatic Cancer Immune Microenvironment and Treatment Response through Integrating in vivo Imaging with ImmunophenotypingNIHNational Cancer Institute2024 to 2025$1,298,946March 8, 2024February 28, 2029YAN, JUNreporter.nih.gov
Role of Zinc Dependent EMT-Transcription Factors (EMT-TF) in Pancreatic Cancer MetastasisNIHNational Cancer Institute2021 to 2024$1,296,900June 1, 2020May 31, 2026LI, MINreporter.nih.gov
CFX Opus 96 Real-Time PCR System for precision genotyping and phenotypingNIHNational Institute of General Medical Sciences2021 to 2024$1,295,701September 1, 2021August 31, 2025YAN, YINGreporter.nih.gov
Utilizing nucleic acid scavengers to elucidate how DNA/RNA-containing DAMPs promote pancreatic cancer metastasis and to mitigate such processesNIHNational Cancer Institute2024 to 2025$1,294,293May 15, 2024April 30, 2029SULLENGER, BRUCE ALANreporter.nih.gov
Isolation and Assessment of Blood-Circulating Cancer Exosomes with LSS and SERS Lab on a Chip Optical Spectroscopic InstrumentNIHNational Cancer Institute2021 to 2022$1,292,552February 1, 2018January 31, 2024PERELMAN, LEV Treporter.nih.gov
Collagen Signaling in Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,289,468May 1, 2024April 30, 2029CRAWFORD, HOWARD C.reporter.nih.gov
Stomal Senescence Regulator of Tumor Immunity and ProgressionNIHNational Cancer Institute2024 to 2025$1,283,816July 1, 2024June 30, 2026DENARDO, DAVID Greporter.nih.gov
Targeted EGFR for basal subtype pancreatic cancerNIHNational Cancer Institute2024 to 2025$1,279,758February 1, 2024January 31, 2029YEH, JEN JENreporter.nih.gov
Development of a theragnostic radiopharmaceutical for pancreatic cancerNIHNational Cancer Institute2024 to 2025$1,275,825June 1, 2024May 31, 2029FERRARA, KATHERINE Wreporter.nih.gov
Molecular strategies for early detection and targeting of cancerNIHNational Cancer Institute2021 to 2022$1,272,193August 12, 2015August 31, 2022REYA, TANNISHTHAreporter.nih.gov
Dissecting mechanisms of tumor initiation via immunomodulationNIHNational Institute of General Medical Sciences2021 to 2024$1,270,500March 17, 2021February 28, 2026LIOU, GEOU-YARHreporter.nih.gov
Role of Hypoxia in Shaping the Tumor Stroma in Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,265,179May 1, 2023April 30, 2028LEE, KYOUNG EUNreporter.nih.gov
Epigenetic Control of Human Beta Cell ProliferationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,263,860April 1, 2018March 31, 2023STEWART, ANDREW F.reporter.nih.gov
Elucidating cancer-intrinsic mechanisms of perineural invasion in pancreatic cancerNIHNational Cancer Institute2022 to 2025$1,259,908July 1, 2022June 30, 2027HWANG, WILLIAM Lreporter.nih.gov
Endoscopic Ultrasound-guided In Vivo Confocal Laser Endomicroscopy as an Imaging Biomarker for the Accurate Risk Stratification of Intraductal Papillary Mucinous NeoplasmsNIHNational Cancer Institute2023 to 2025$1,255,444April 1, 2023March 31, 2028KRISHNA, SOMASHEKAR G.reporter.nih.gov
Systems Metabolic Approach for Multi-scale Pancreatic Cancer PhenotypingNIHNational Cancer Institute2024 to 2025$1,252,683August 1, 2024July 31, 2029JAMSHIDI, NEEMAreporter.nih.gov
Lysosome Trapped FAP-Targeted Theranostics for Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,247,835March 18, 2024February 28, 2029GARRISON, JERED Creporter.nih.gov
Peripheral Nerve Regulation of Pancreas Cancer ProgressionNIHNational Cancer Institute2024 to 2025$1,245,096July 1, 2024June 30, 2029SALOMAN, JAMI LYNNreporter.nih.gov
Innovative mRNA vaccines to enhance the efficacy of T-cell transfer therapies against solid tumorsNIHNational Cancer Institute2024 to 2025$1,242,623August 1, 2024July 31, 2029RADU, CAIUS GABRIELreporter.nih.gov
Preclinical Models for Cancer Therapeutic DevelopmentNIHNational Cancer Institute2021 to 2025$1,240,225September 15, 2016August 31, 2026PARK, YOUNGKYUreporter.nih.gov
Adoptive T Cell Therapy for Pancreatic CancerNIHNational Cancer Institute2021 to 2023$1,237,671August 1, 2019July 31, 2025YEE, CASSIANreporter.nih.gov
Optimizing Theranostic Dosimetry and Kidney Biomarkers for Alpha-Emitter Radioligand Therapy in Neuroendocrine TumorsNIHNational Cancer Institute2024 to 2025$1,227,146July 1, 2024June 30, 2029ZEPEDA-OROZCO, DIANAreporter.nih.gov
Targeting the Stroma for Pancreatic Cancer TreatmentNIHNational Cancer Institute2021 to 2025$1,220,860May 1, 2021March 31, 2026OSIPOV, ARSENreporter.nih.gov
Tools to Study Electrophilic Stress and Develop Covalent DrugsNIHNational Institute of General Medical Sciences2021 to 2024$1,220,000August 1, 2020November 30, 2025FRANZINI, RAPHAEL M.reporter.nih.gov
Biomarker validation for intraductal papillary mucinous neoplasms of the pancreasNIHNational Cancer Institute2023 to 2025$1,215,381September 1, 2014June 30, 2028ALLEN, PETER Jreporter.nih.gov
Leveraging CD26high Meso-CAR T cells in patients with advanced pancreatic cancerNIHNational Cancer Institute2024 to 2025$1,214,170February 1, 2024January 31, 2029LESINSKI, GREGORY B.reporter.nih.gov
Reprogramming PDAC Stroma by Targeting Coagulation in the Tumor MicroenvironmentNIHNational Cancer Institute2022 to 2023$1,214,099September 1, 2022January 16, 2024HAN, BUMSOOreporter.nih.gov
Exploiting gold nanoparticle as a probe to identify therapeutic targetsNIHNational Cancer Institute2022 to 2025$1,212,885December 15, 2021November 30, 2027MUKHERJEE, PRIYABRATAreporter.nih.gov
Legumain to the rescue: A new ADC linker strategy to address the limitations of cathepsin cleavageNIHNational Institute of General Medical Sciences2022 to 2025$1,212,224February 10, 2022December 31, 2026TUMEY, LAWRENCEreporter.nih.gov
Stromal targeting to improve the efficacy of systemically administered drugs for pancreatic ductal adenocarcinomasNIHNational Cancer Institute2024 to 2025$1,205,464September 1, 2024August 31, 2029SOLORIO, LUISreporter.nih.gov
Modulating innate immune cells in the tumor microenvironment of pancreas cancer to enhance anti-tumor immunityNIHNational Cancer Institute2021 to 2023$1,194,641July 1, 2013December 31, 2024LINEHAN, DAVID Creporter.nih.gov
Elucidating The Adaptive Role Of Serine Codons During Pancreatic TumorigenesisNIHNational Cancer Institute2024 to 2025$1,191,400March 6, 2024February 28, 2029BANH, ROBERT SINGHUNGreporter.nih.gov
Functions of the LKB1 tumor suppressor in control in metabolism and epigeneticsNIHNational Cancer Institute2021 to 2022$1,186,156January 1, 2018December 31, 2023EL-BARDEESY, NABEELreporter.nih.gov
Development of a New Strategy to Treat Locally Advanced Pancreatic CancerNIHNational Cancer Institute2021 to 2023$1,184,726May 1, 2019April 30, 2024GERBER, SCOTT ANDREWreporter.nih.gov
Penn Quantitative MRI Resource for Pancreatic CancerNIHNational Cancer Institute2021 to 2022$1,182,130September 14, 2018August 31, 2024ZHOU, RONGreporter.nih.gov
Genetically-engineered Bacteria Overcome Therapy ResistanceNIHNational Cancer Institute2024 to 2025$1,175,786July 1, 2024June 30, 2026WEICHSELBAUM, RALPH Rreporter.nih.gov
Fully Quantitative Low-Dose, Motion-Resolved Dynamic Contrast-Enhanced MRI in Pancreatic AdenocarcinomaNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2023$1,172,300June 15, 2022August 31, 2023CHRISTODOULOU, ANTHONY Greporter.nih.gov
ProAgio in Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,167,913July 1, 2024June 30, 2029EL-RAYES, BASSELreporter.nih.gov
Multimodal AI Fusion Model for Early Detection for Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,166,286September 16, 2024August 31, 2029BANERJEE, IMONreporter.nih.gov
Regulation and targeting of tumor cell states and plasticity in pancreatic cancerNIHNational Cancer Institute2022 to 2025$1,164,735September 1, 2022August 31, 2027RAGHAVAN, SRIVATSANreporter.nih.gov
Targeting pancreatic cancer metastases with TargefrinNIHNational Cancer Institute2025$1,162,000April 30, 2024August 31, 2027BAGGIO, CARLOreporter.nih.gov
Biased chemokine receptor signaling in cancer progressionNIHNational Cancer Institute2021 to 2023$1,160,004January 1, 2019December 31, 2024DWINELL, MICHAEL Breporter.nih.gov
High dose radiation therapy to direct immune responses to pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,159,951June 15, 2014May 31, 2024GOUGH, MICHAEL JAMESreporter.nih.gov
Developing MRI-Guided Preventive Dendritic Cell Vaccination Strategy to Avoid Post-surgical Pancreatic Cancer Recurrence and MetastasisNIHNational Cancer Institute2023 to 2025$1,157,875August 1, 2016May 31, 2028ZHANG, ZHUOLIreporter.nih.gov
Characterizing the sources, mechanisms, and translational relevance of microbial TMAO in driving anti-tumor immunity in pancreatic cancer.NIHNational Cancer Institute2024 to 2025$1,154,029March 6, 2024February 28, 2029SHINDE, RAHUL SURESHreporter.nih.gov
Vitamin B6 Modulates NK Cell Metabolism in Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,153,907July 5, 2023August 31, 2028MEHLA, KAMIYAreporter.nih.gov
Regulation of PDAC metabolism and immunity by collagen and its cleavage productsNIHNational Cancer Institute2025$1,152,768September 1, 2025August 31, 2027KARIN, MICHAELreporter.nih.gov
PROFILING SIGNALING ACTIVITY AND GENE EXPRESSION IN SINGLE, PANCREATIC ADENOCARCINOMA CELLS USING CE-RNA-SEQNIHNational Cancer Institute2021 to 2022$1,151,943April 1, 2018March 31, 2024ALLBRITTON, NANCY L.reporter.nih.gov
Commercialization of Algorithmic Non-thermal Ablation Technology for the Treatment of Inoperable TumorsNIHNational Cancer Institute2025$1,150,000September 16, 2022August 31, 2027FONG, JORDANreporter.nih.gov
Combining Machine Learning and Nanofluidic Technology for The Multiplexed Diagnosis of Pancreatic AdenocarcinomaNIHNational Cancer Institute2023 to 2025$1,147,749June 1, 2023May 31, 2027ISSADORE, DAVID AARONreporter.nih.gov
SBIR: In vivo engineering of multifaceted B7H3.CAR-T cells for cellular immunotherapy of pancreatic ductal adenocarcinomaNIHNational Cancer Institute2025$1,146,618September 16, 2025August 31, 2027YANG, MINGreporter.nih.gov
Role of SETD5 in Chromatin Regulation and TumorigenesisNIHNational Cancer Institute2021 to 2023$1,143,273April 1, 2019March 31, 2024MAZUR, PAWEL K.reporter.nih.gov
Molecular Imaging Guidance for Potentiating Chemoimmunotherapy in Pancreatic Cancer using Photodynamic PrimingNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$1,129,001July 1, 2024April 30, 2028OBAID, GIRGISreporter.nih.gov
Interrogate the interaction between tumor cells and nerves in the tumor microenvironment of pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,128,812August 2, 2013August 31, 2024ZHENG, LEIreporter.nih.gov
Metabolic vulnerability due to dysregulated lipid metabolism in PDAC cachexiaNIHNational Cancer Institute2023 to 2025$1,127,838September 22, 2023August 31, 2028GROSSBERG, AARONreporter.nih.gov
Macropinocytosis Inhibition as a Glutamine Mimetic Sensitization Strategy in Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,127,010July 17, 2024June 30, 2029COMMISSO, COSIMOreporter.nih.gov
Epigenetic regulation of pancreatic cancer subtype identity and tumorigenesis by PHF2NIHNational Cancer Institute2023 to 2025$1,117,894July 7, 2023June 30, 2028LISS, ANDREWreporter.nih.gov
A novel monobody-drug conjugate to treat mutant KRas pancreatic cancer.NIHNational Cancer Institute2025$1,113,257August 1, 2022August 31, 2027RAMIREZ, CRAIG PATRICKreporter.nih.gov
Tumor-intrinsic and paracrine roles of endoglin in pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,110,032August 1, 2023July 31, 2028LEE, NAM Yreporter.nih.gov
Role of Daxx in protein folding and tumorigenesisNIHNational Cancer Institute2021 to 2023$1,100,287September 1, 2019August 31, 2025YANG, XIAOLUreporter.nih.gov
CEACAM5-targeted activation of potent chemotherapeutics via bioorthogonal click chemistryNIHNational Cancer Institute2025$1,094,189September 25, 2025August 31, 2027MEJIA ONETO, JOSE Mreporter.nih.gov
Resistance Mechanisms to Combined Trametinib and 4-aminoquinolones in the Inhibition of Pancreatic CancerNIHNational Cancer Institute2021 to 2024$1,091,776July 1, 2020June 30, 2026KINSEY, CONANreporter.nih.gov
Lipid storage and catabolism as drivers of metastatic invasionNIHNational Cancer Institute2023 to 2025$1,089,149September 19, 2023August 31, 2028RAZIDLO, GINA LYNNreporter.nih.gov
Normalizing PDAC stroma with PCBP2 siRNA nanoparticles to improve the antitumor activity of chemotherapy and immunotherapyNIHNational Cancer Institute2023 to 2025$1,085,343April 1, 2023March 31, 2028CHENG, KUNreporter.nih.gov
Elucidating and targeting subtype-specific driver in pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,083,360April 1, 2019March 31, 2024YING, HAOQIANGreporter.nih.gov
Interrogating the Spatial and Functional Relevance of Microbes in Pancreatic Cancer and MetastasisNIHNational Cancer Institute2024 to 2025$1,078,684August 1, 2024July 31, 2029MCALLISTER, FLORENCIAreporter.nih.gov
Enhancing the therapeutic effect of receptor radionuclide therapy in neuroendocrine tumors by somatostatin receptor upregulationNIHNational Cancer Institute2021 to 2024$1,078,668July 1, 2020June 30, 2025HEIDARI, PEDRAMreporter.nih.gov
Clinical Validation Center for Early Detection of Pancreatic CancerNIHNational Cancer Institute2025$1,076,354May 4, 2016August 31, 2027MAITRA, ANIRBANreporter.nih.gov
Advancing the Clinical Translation of Cyst Fluid Assays for Early Detection of Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,075,185May 16, 2023April 30, 2028KIRKWOOD, KIMBERLY SAUNDERSreporter.nih.gov
Wnt/?-catenin Signaling in Pancreatic OncogenesisNIHNational Cancer Institute2021 to 2023$1,072,598September 14, 2017May 31, 2024MAITRA, ANIRBANreporter.nih.gov
Molecular Imaging of Fibrosis for Improved Treatment Planning of Pancreatic Ductal AdenocarcinomaNIHNational Cancer Institute2022 to 2025$1,070,516July 1, 2022June 30, 2027ABDAR ESFAHANI, SHADIreporter.nih.gov
Mechanisms of injury-induced pancreatic neoplasiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,067,718April 1, 2020December 31, 2024BIALKOWSKA, AGNIESZKA BEATAreporter.nih.gov
Neoantigen-Targeted Vaccines in Combination with Immune Checkpoint Inhibitors for Pancreatic CancerNIHNational Cancer Institute2021 to 2025$1,066,742July 1, 2021June 30, 2026ZAIDI, NEEHAreporter.nih.gov
Mechanism by which ketogenic diet uncouples tumor growth and overall survivalNIHNational Cancer Institute2024 to 2025$1,062,713June 6, 2024May 31, 2029JANOWITZ, TOBIASreporter.nih.gov
Role of ICAM1 in development and progression of pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,059,662March 1, 2019August 31, 2025STORZ, PETERreporter.nih.gov
Exploiting the Twist1 network in cancer cachexiaNIHNational Cancer Institute2021 to 2023$1,054,221June 1, 2019May 31, 2025ATFI, AZEDDINEreporter.nih.gov
Personalized preclinical models in pancreas cancer: a tractable approach to precision medicineNIHNational Cancer Institute2021 to 2024$1,050,892April 1, 2020March 31, 2025BURKHART, RICHARD ANDREWreporter.nih.gov
Modeling and targeting tumor-immune signaling interactions in tumor microenvironmentNIHNational Library of Medicine2023 to 2025$1,050,375May 16, 2023February 28, 2027LI, FUHAIreporter.nih.gov
The Impact of Macrophage Origin on the Pathogenesis and Treatment Resistance of Pancreatic CancerNIHNational Cancer Institute2021 to 2023$1,048,950April 1, 2014April 30, 2025DENARDO, DAVID Greporter.nih.gov
Advanced Oncolytic Adenovirus Enabling Systemic Therapy of PDACNIHNational Cancer Institute2023 to 2025$1,045,961December 12, 2022November 30, 2027YAMAMOTO, MASATOreporter.nih.gov
SLC6A14 as a unique drug target to treat pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,043,289May 12, 2023April 30, 2028BHUTIA, YANGZOM DOMAreporter.nih.gov
Combination therapy with IFN expressing oncolytic adenovirus for pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,042,735February 5, 2019January 31, 2025YAMAMOTO, MASATOreporter.nih.gov
Multifactor risk scores with susceptibility gene mutations to enhance risk assessment of pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,032,669September 19, 2023August 31, 2028OBERG, ANN LAURAreporter.nih.gov
Counteracting molecular mechanisms of obesity dependent PDAC progressionNIHNational Cancer Institute2021 to 2023$1,030,933June 10, 2019November 30, 2024VANSAUN, MICHAEL NATHANreporter.nih.gov
Contributions of the Adipose Tissue to the Development of Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,029,975February 8, 2024January 31, 2029CRUZ-MONSERRATE, ZOBEIDAreporter.nih.gov
Targeting immune stroma interactions in pancreatic cancerNIHNational Cancer Institute2021 to 2023$1,027,262July 15, 2019June 30, 2025LESINSKI, GREGORY B.reporter.nih.gov
Sialylation-dependent mechanisms driving pancreatic cancer progressionNIHNational Cancer Institute2021 to 2022$1,026,503September 18, 2018August 31, 2024BELLIS, SUSAN Lreporter.nih.gov
High Throughput Screening for SCAP Inhibitors as Pancreas Cancer TherapeuticsNIHNational Cancer Institute2022 to 2024$1,018,723July 1, 2022June 30, 2025ESPENSHADE, PETER J.reporter.nih.gov
Proteostasis Reprogramming in Mutant KRAS-Driven CancersNIHNational Cancer Institute2024 to 2025$1,016,261December 1, 2022May 31, 2028CHEN, XIreporter.nih.gov
Impact of CREB-driven mechanism in shaping the tumor-immune landscapeNIHNational Cancer Institute2023 to 2025$1,012,439January 1, 2023December 31, 2027NAGATHIHALLI, NAGARAJ S.reporter.nih.gov
PASSCODE (Pancreatic Adenocarcinoma Stromal Reprograming ConSortium COordination, Data Management and Education)NIHNational Cancer Institute2025$1,010,953September 16, 2022August 31, 2027MAITRA, ANIRBANreporter.nih.gov
Cost Effectiveness of Germline Genetic Testing in Pancreatic CancerNIHNational Cancer Institute2021 to 2024$1,009,656March 1, 2020August 31, 2025PETERS, MARY LINTON Breporter.nih.gov
Targeting NADPH Oxidase for Pancreatic Cancer Prevention and TherapyNIHNational Cancer Institute2022 to 2024$1,008,239August 1, 2020August 31, 2025LU, WEIQINreporter.nih.gov
Targeting MUC1-Mediated Tumor-Stromal Metabolic Cross-Talk in Pancreatic CancerNIHNational Cancer Institute2022 to 2023$991,317September 25, 2012August 31, 2025SINGH, PANKAJ KUMARreporter.nih.gov
Controllable In Vivo Genome Editing for Immune-Checkpoint Blockade in Solid TumorsNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$989,015August 21, 2018May 31, 2024TONG, SHENGreporter.nih.gov
Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and BiofluidsNIHNational Cancer Institute2022 to 2024$988,221March 15, 2022February 28, 2026DRAKE, RICHARD R.reporter.nih.gov
Curation Expert Panels for BRCA1/2 and Hereditary Breast, Ovarian and Pancreatic (HBOP) Cancer GenesNIHNational Cancer Institute2022 to 2025$987,571August 10, 2022July 31, 2028COUCH, FERGUS JOSEPHreporter.nih.gov
Targeting the Unfolded Protein Response in PanNETsNIHNational Cancer Institute2021 to 2022$978,996August 12, 2019December 31, 2023OAKES, SCOTT A.reporter.nih.gov
Exploiting the Ref-1 node in pancreatic cancer: tailoring new pancreatic cancer therapy using multi-targeted combinationsNIHNational Cancer Institute2021 to 2022$977,578January 1, 2013February 28, 2025KELLEY, MARK R.reporter.nih.gov
A novel, glutathione-dependent metabolic pathway drives metastatic outgrowth in pancreatic cancerNIHNational Cancer Institute2024 to 2025$971,116July 1, 2024June 30, 2026MOSTOSLAVSKY, RAULreporter.nih.gov
HRD-IA signatures in pancreatic ductal adenocarcinomaNIHNational Cancer Institute2022 to 2024$966,110February 1, 2022January 31, 2025BORAD, MITESHreporter.nih.gov
Elucidation of hypoxia-induced metastatic reprogramming through the regulation of KDM8 function in pancreatic cancerNIHNational Cancer Institute2024 to 2025$960,365January 1, 2024December 31, 2028CHIOU, SHIN-HENGreporter.nih.gov
Precision Management of Cystic Precursors to Pancreatic CancerNIHNational Cancer Institute2021 to 2024$959,714July 1, 2019December 31, 2025PANDHARIPANDE, PARI VIJAYreporter.nih.gov
Targeting LIF/LIFR in pancreatic cancerNIHNational Cancer Institute2021$956,072April 2, 2019April 30, 2023NAIR, HAREESH BABUreporter.nih.gov
Exploring the role and potential of anti-viral drugs to sensitize cancer cells to chemotherapyNIHNational Cancer Institute2024 to 2025$944,710June 1, 2024May 31, 2029YI, QINGreporter.nih.gov
Hepatic metabolic reprogramming drives pancreatic cancer cachexiaNIHNational Cancer Institute2021 to 2024$943,806July 3, 2020June 30, 2025GROSSBERG, AARONreporter.nih.gov
A Pilot Clinical Trial of Paricalcitol for Chronic PancreatitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$939,488September 15, 2022June 30, 2025PANDOL, STEPHEN J.reporter.nih.gov
Exploring Collateral Lethality for Development of Cancer TherapeuticsNIHNational Cancer Institute2021 to 2022$938,366April 9, 2018March 31, 2024DEPINHO, RONALD ANTHONYreporter.nih.gov
Defining pro-metastatic drivers in the pancreatic cancer tumor microenvironmentNIHNational Cancer Institute2024 to 2025$904,617September 1, 2024August 31, 2029KIM, MICHAEL PAULreporter.nih.gov
Collagen fibers and fragments regulate pancreatic cancer metabolism and growth.NIHNational Cancer Institute2024 to 2025$903,743March 1, 2024August 31, 2025KARIN, MICHAELreporter.nih.gov
Biomarker Validation in Pancreatic Cystic NeoplasmsNIHNational Cancer Institute2023$898,256September 15, 2023March 15, 2024SIMEONE, DIANE Mreporter.nih.gov
Targeting Metabolic Crosstalk in Pancreatic CancerNIHNational Cancer Institute2024 to 2025$881,750May 1, 2024April 30, 2029HALBROOK, CHRISTOPHER J.reporter.nih.gov
Chemical pancreatectomy for chronic pancreatitis and pancreatic cancerNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$881,168August 8, 2019April 30, 2024GITTES, GEORGE K.reporter.nih.gov
Polyunsaturated fatty acids supplementation and Lipocalin 2 blockade in preventing pancreatic cancerNIHNational Cancer Institute2021 to 2022$871,200July 19, 2018June 30, 2024CRUZ-MONSERRATE, ZOBEIDAreporter.nih.gov
Exosomes as Endocrine Signaling Molecules in Cancer CachexiaNIHNational Cancer Institute2021 to 2022$870,788May 10, 2018April 30, 2023MARKS, DANIEL L.reporter.nih.gov
Biomarker Validation in Pancreatic Cystic NeoplasmsNIHNational Cancer Institute2024 to 2025$869,561September 15, 2023August 31, 2029SIMEONE, DIANE Mreporter.nih.gov
Targeting HMGA1 Tumor-Stromal Networks in Pancreatic CarcinogenesisNIHNational Cancer Institute2024 to 2025$869,307July 1, 2024June 30, 2026RESAR, LINDA M Sreporter.nih.gov
Elucidating the molecular and cellular mechanisms of immune evasion in pancreatic cancerNIHNational Cancer Institute2022 to 2025$864,895July 1, 2022June 30, 2027FREED-PASTOR, WILLIAM Areporter.nih.gov
Physiologic mechanisms of ion channel regulationNIHNational Institute of General Medical Sciences2024 to 2025$864,545April 1, 2024January 31, 2029CARLSON, ANNE Ereporter.nih.gov
Investigating Cellular Communication in the Tumor Microenvironment in Pancreatic CancerNIHNational Cancer Institute2022 to 2024$861,813July 1, 2021August 31, 2025STEELE, NINA Greporter.nih.gov
Intersection of cytoskeletal regulation with tumor cell metabolismNIHNational Cancer Institute2024 to 2025$858,158September 1, 2024August 31, 2029RAZIDLO, GINA LYNNreporter.nih.gov
Directing the metabolic fate of CAR T cellsNIHNational Cancer Institute2021 to 2022$855,970March 1, 2018February 28, 2023JUNE, CARL H.reporter.nih.gov
Targeting Dectin-2 on Tumor-associated Macrophages for the Treatment of CancerNIHNational Cancer Institute2021 to 2022$854,465June 1, 2018May 31, 2023ENGLEMAN, EDGAR G.reporter.nih.gov
Development of a companion diagnostic to identify patients who respond to microbiome-targeting drugsNIHNational Institute of General Medical Sciences2021$846,715April 1, 2018December 31, 2023WALLACE, BRET DAVIDreporter.nih.gov
Microbial Dysbiosis in Pancreatic Cancer Initiation and ProgressionNIHNational Cancer Institute2023 to 2025$842,010August 1, 2023July 31, 2028DALEY, DONNELEreporter.nih.gov
Mechanism of APE1 in DNA damage responseNIHNational Cancer Institute2021 to 2022$836,350February 13, 2018January 31, 2024YAN, SHANreporter.nih.gov
Elucidating the mechanism of Ga13 mediated tumor suppression in pancreatic cancerNIHNational Cancer Institute2024 to 2025$831,796August 12, 2024July 31, 2028SHIELDS, MARIOreporter.nih.gov
ROLES AND MECHANISMS OF TERTIARY LYMPHOID STRUCTURES IN ANTI-TUMOR IMMUNITYNIHNational Cancer Institute2024 to 2025$830,678January 1, 2024December 31, 2028GUNDERSON, ANDREWreporter.nih.gov
Mutant p53 gain-of-function as an actionable target in cancer therapyNIHNational Cancer Institute2021 to 2024$828,596September 11, 2020August 31, 2025NEMAJEROVA, ALICEreporter.nih.gov
CHARM 2: Chemotherapy for ablation and resolution of mucinous pancreatic cysts: a prospective, randomized, double-blind, multi-center clinical trialNIHNational Cancer Institute2021 to 2022$822,830August 1, 2018July 31, 2024MOYER, MATTHEW T.reporter.nih.gov
Harnessing the therapeutic potential of histotripsy focused ultrasound-induced immunogenic cancer cell deathNIHNational Cancer Institute2024 to 2025$817,263August 3, 2024May 31, 2028CHO, CLIFFORDreporter.nih.gov
Response and resistance to chimeric antigen receptor T cell therapy in human solid tumors using spatial multi-omicsNIHOffice of the Director, National Institutes of Health2024 to 2025$812,500September 18, 2024July 31, 2029RECH, ANDREW JOHNreporter.nih.gov
Tumor Subtypes and Therapy Response in Pancreatic CancerNIHNational Cancer Institute2021$806,124September 1, 2016July 31, 2022YEH, JEN JENreporter.nih.gov
Role of nonsense mediated RNA decay in pancreatic cancerNIHNational Cancer Institute2021 to 2022$798,786July 1, 2018June 30, 2024PHILIPS, MARK REIDreporter.nih.gov
Targeting CXCR2 axis in Pancreatic CancerNIHNational Cancer Institute2021 to 2022$797,067March 6, 2018February 28, 2025SINGH, RAKESH Kreporter.nih.gov
Targeting nutrient microenvironment imprinted therapy resistance in pancreatic cancerNIHNational Cancer Institute2024 to 2025$792,504March 15, 2024February 28, 2029MUIR, ALEXANDERreporter.nih.gov
Immune Activating CAR-Modified Antigen Presenting CellsNIHOffice of the Director, National Institutes of Health2021 to 2022$787,500September 19, 2018August 31, 2024DESELM, CARLreporter.nih.gov
SOAT1 as a targetable dependency in Pancreatic AdenocarcinomaNIHNational Cancer Institute2025$778,873June 23, 2025May 31, 2030TUVESON, DAVID Areporter.nih.gov
High Throughput Digital Droplet Assays for Ultrasensitive Multimodal (DNA, RNA, and Protein) DiagnosticsNIHNational Cancer Institute2024 to 2025$773,668March 7, 2024August 31, 2027ISSADORE, DAVID AARONreporter.nih.gov
Dectin-1 signaling drives pancreatic oncogenesis by inducing macrophage-mediated adaptive immune suppressionNIHNational Cancer Institute2021 to 2022$767,708December 15, 2017November 30, 2023WONG, KWOK KINreporter.nih.gov
Mitophagy in Tumor MicroenvironmentNIHNational Cancer Institute2022 to 2023$761,287September 10, 2012March 31, 2025TANG, DAOLINreporter.nih.gov
Reprogramming the Tumor Microenvironment in Pancreas Cancer to Enhance ImmunotherapyNIHNational Cancer Institute2021 to 2022$759,825April 1, 2012January 31, 2024MERCHANT, NIPUN B.reporter.nih.gov
Development of Quinoxaline Based IKKbeta Inhibitors for Kras Driven CancersNIHNational Cancer Institute2023 to 2025$748,314May 9, 2016July 31, 2025NATARAJAN, AMARNATH (AMAR)reporter.nih.gov
Cellular mechanisms and therapeutic possibilities of inhibiting oncogenic KRASNIHNational Cancer Institute2021 to 2023$747,000September 1, 2018August 31, 2025WOLFE, ANDREW Lreporter.nih.gov
Targeting aspartate biosynthesis in pancreatic tumorsNIHNational Cancer Institute2022 to 2024$747,000July 1, 2020November 30, 2024GARCIA BERMUDEZ, JAVIERreporter.nih.gov
Experimental evolution of pancreatic cancerNIHNational Cancer Institute2022 to 2024$747,000September 9, 2019July 31, 2026MAKOHON-MOORE, ALVINreporter.nih.gov
Dissecting the oncogenic and pro-metastatic roles of PTHLH-mediated calcium signaling in pancreatic cancerNIHNational Cancer Institute2022 to 2024$747,000July 1, 2021July 31, 2025PITARRESI, JASON R.reporter.nih.gov
Role of Gstt1 in metastatic maintenance and self-renewal in PDANIHNational Cancer Institute2022 to 2024$747,000September 1, 2022August 31, 2025FERRER, CHRISTINAreporter.nih.gov
Function of mesothelial cells in the tumor microenvironment of pancreatic ductal adenocarcinomaNIHNational Cancer Institute2023 to 2025$747,000December 1, 2022November 30, 2026HUANG, HUOCONGreporter.nih.gov
Integrating epidemiologic, clinical, genomic and metabolomic profiles to predict pancreatic cancer risk in a multiethnic populationNIHNational Cancer Institute2023 to 2025$747,000January 9, 2023December 31, 2026HUANG, BRIANreporter.nih.gov
Investigating the metabolic regulation of tumor desmoplasiaNIHNational Cancer Institute2023 to 2025$747,000January 8, 2023December 31, 2025SCHWÖRER, SIMONreporter.nih.gov
Interrogating the RAS interactome for therapeutic vulnerabilitiesNIHNational Cancer Institute2023 to 2025$746,222March 10, 2020December 31, 2025ADHIKARI, HEMAreporter.nih.gov
Understanding omega-3 and 6 fatty acid dependent regulation of inflammatory signals in pancreatic cancerNIHNational Cancer Institute2025$745,320September 1, 2025August 31, 2030KAECH, SUSAN Mreporter.nih.gov
Characterization of polyamine biosynthetic enzymes from human gut microbes associated with colon and pancreatic cancerNIHNational Institute of General Medical Sciences2022 to 2025$744,530July 15, 2022June 30, 2027MCFARLANE, JEFFREY Sreporter.nih.gov
BRAVE hydrogels for interrogating cell-matrix interactions in pancreatic desmoplasiaNIHNational Cancer Institute2021 to 2022$744,222December 20, 2018November 30, 2023LIN, CHIEN-CHIreporter.nih.gov
TROP2-Directed CAR-NK Cells for the Immunotherapy of Pancreatic CancerNIHNational Cancer Institute2024 to 2025$741,150April 5, 2024March 31, 2029BASAR, RAFETreporter.nih.gov
Priming pancreatic ductal adenocarcinoma using blood thinners to sensitize the efficacy of checkpoint immunotherapyNIHNational Institute of General Medical Sciences2022 to 2023$740,250July 5, 2022May 31, 2024AL-HILAL, TASLIM Areporter.nih.gov
Measuring and manipulating metabolic fluxes in the tumor microenvironmentNIHNational Cancer Institute2023 to 2025$739,764September 1, 2022August 31, 2026BARTMAN, CAROLINEreporter.nih.gov
Developing methods for advancing the early detection of pancreatic ductal adenocarcinoma leveraging electronic medical records dataNIHNational Cancer Institute2025$739,640September 1, 2025August 31, 2030ZHAO, YINGQIreporter.nih.gov
Targeting tumor and its microenvironment using nanotherapeutics for pancreatic cancerNIHNational Cancer Institute2021 to 2022$737,469August 1, 2020September 30, 2022RACHAGANI, SATYANARAYANAreporter.nih.gov
Uncovering Causal Protein Markers to Characterize Pancreatic Cancer Etiology and Improve Risk PredictionNIHNational Cancer Institute2024 to 2025$737,445September 18, 2024September 14, 2025WU, LANGreporter.nih.gov
Targeting tumor and its microenvironment using nanotherapeutics for pancreatic cancerNIHNational Cancer Institute2023 to 2024$736,832August 1, 2020April 30, 2026RACHAGANI, SATYANARAYANAreporter.nih.gov
Mechanistic insights into lysosomal nutrient efflux in cancerNIHNational Cancer Institute2022 to 2024$735,010September 1, 2022August 31, 2025ROGALA, KACPERreporter.nih.gov
The Pancreatic Cancer MicroenvironmentNIHNational Cancer Institute2022 to 2023$731,091June 8, 2017March 31, 2025KANG, RUIreporter.nih.gov
Critical Resources Provided by UNMC RAP Biorepository Stimulate Cancer ResearchNIHNational Cancer Institute2021 to 2025$722,997September 15, 2016August 31, 2026GRANDGENETT, PAUL Mreporter.nih.gov
Imaging zinc secretion from the exocrine pancreas for the early diagnosis of pancreatic adenocarcinoma with MRINIHNational Cancer Institute2021 to 2024$722,827May 1, 2024August 20, 2024CLAVIJO JORDAN, MARIA VERONICAreporter.nih.gov
Deregulation of COMPASS complex and enhancer chromatin in pancreatic cancerNIHNational Cancer Institute2021 to 2022$722,415July 1, 2018June 30, 2024TZATSOS, ALEXANDROSreporter.nih.gov
Integrative bioinformatics and functional characterization of oncogenic driver aberrations in cancerNIHNational Cancer Institute2021$721,618August 8, 2018July 31, 2023MILLS, GORDON B.reporter.nih.gov
Imaging the native 3D architecture of pancreatic and breast tumor patient tissue at single-cell resolutionNIHNational Cancer Institute2021 to 2022$720,562August 3, 2021July 31, 2024OH, STEPHEN TRACYreporter.nih.gov
Galpha13 and pancreatic cancer progressionNIHNational Cancer Institute2021 to 2022$719,838April 1, 2018March 31, 2024MUNSHI, HIDAYATULLAH G.reporter.nih.gov
Training and Research on Mechanisms of Pancreatic Cancer Associated Muscle Wasting and Related TherapiesNIHNational Cancer Institute2021 to 2025$713,515August 9, 2021July 31, 2026COLE, CALVIN LLOYDreporter.nih.gov
Dissecting roles of Lunatic Fringe-dependent Notch signaling in pancreatic cancerNIHNational Cancer Institute2024 to 2025$709,126May 1, 2024April 30, 2029XU, KELIreporter.nih.gov
Optimizing Pancreatic Cancer Management with Next Generation Imaging and Liquid BiopsyNIHNational Cancer Institute2024 to 2025$702,343April 1, 2021March 31, 2027COLLISSON, ERICreporter.nih.gov
Disrupting MDSC-fibroblast interactions to overcome chemoimmunotherapy resistance in pancreatic cancerNIHNational Cancer Institute2024 to 2025$702,262August 28, 2024July 31, 2029DATTA, JASHODEEPreporter.nih.gov
Defining metabolic adaptations within the PDAC "arid" tumor microenvironmentNIHNational Cancer Institute2021 to 2022$702,169May 1, 2021September 30, 2022DANG, CHI V.reporter.nih.gov
Role of BNIP3 and mitophagy in muscle atrophy and cancer cachexiaNIHNational Cancer Institute2025$698,076December 5, 2024November 30, 2029MACLEOD, KAY Freporter.nih.gov
Metabolic compartmentalization and the regulation of histone propionylation in cancerNIHNational Cancer Institute2025$698,008April 1, 2025March 31, 2030WELLEN, KATHRYN ELAINEreporter.nih.gov
Targeting pancreatic endocrine-exocrine signaling in cancer development with incretin mimeticsNIHNational Cancer Institute2025$693,075February 1, 2025December 31, 2029MUZUMDAR, MANDAR DEEPAKreporter.nih.gov
Mechanism and Anti-Cancer Activity of SCFA-Hexosamine AnalogsNIHNational Cancer Institute2021 to 2022$693,031September 1, 2005December 31, 2024YAREMA, KEVIN Jreporter.nih.gov
Magnetic Resonance (MR) Fingerprinting for Quantification of Pancreatic Tumor MicrovasculatureNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$693,000January 1, 2019November 30, 2024GUIMARAES, ALEXANDER SAVIO RAMOSreporter.nih.gov
5mC and 5hmC DNA alterations as sensitive and specific biomarkers for the non-invasive early detection of pancreatic ductal adenocarcinomaNIHNational Cancer Institute2025$690,637September 1, 2025August 31, 2030GOEL, AJAYreporter.nih.gov
A novel molecular cross-talk driving pancreatic cancer progressionNIHNational Cancer Institute2021 to 2022$686,181January 1, 2018December 31, 2023SINGH, AJAY PRATAPreporter.nih.gov
Mutant p53 as actionable cancer-specific targetNIHNational Cancer Institute2021 to 2022$681,979April 1, 2013May 31, 2025MOLL, UTE MARTHAreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of TX MD Anderson Can CTRHouston, TX42$67.5 million0$0
University of Michigan at Ann ArborAnn Arbor, MI48$39.3 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY28$33.2 million0$0
Columbia University Health SciencesNew York, NY23$32 million0$0
H. Lee Moffitt Cancer CTR & Res InstTampa, FL5$31.7 million0$0
Johns Hopkins UniversityBaltimore, MD29$31.3 million0$0
University of PennsylvaniaPhiladelphia, PA31$27.8 million0$0
Massachusetts General HospitalBoston, MA24$26.3 million0$0
Stanford UniversityStanford, CA19$25.7 million0$0
University of Nebraska Medical CenterOmaha, NE23$23.9 million0$0
University of California, San FranciscoSan Francisco, CA22$23.9 million0$0
Washington UniversitySaint Louis, MO23$23.3 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC22$22.7 million0$0
New York University School of MedicineNew York, NY18$21.8 million0$0
Oregon Health & Science UniversityPortland, OR21$21.7 million0$0
University of California, San DiegoLa Jolla, CA20$19.9 million0$0
Dana-Farber Cancer InstBoston, MA17$18.9 million0$0
Mayo Clinic RochesterRochester, MN14$17.8 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA14$17.3 million0$0
Salk Institute for Biological StudiesLa Jolla, CA5$16.8 million0$0
Fred Hutchinson Cancer CenterSeattle, WA12$14.8 million0$0
Beckman Research Institute/city of HopeDuarte, CA7$14.7 million0$0
Indiana University IndianapolisIndianapolis, IN12$14.2 million0$0
University of FloridaGainesville, FL9$13.6 million0$0
University of California Los AngelesLos Angeles, CA9$13.2 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA11$13.2 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY12$12.8 million0$0
Ohio State UniversityColumbus, OH12$12.1 million0$0
Ut Southwestern Medical CenterDallas, TX12$11.4 million0$0
University of Oklahoma HLTH Sciences CTROklahoma City, OK12$11 million0$0
Beth Israel Deaconess Medical CenterBoston, MA6$10 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX7$9.9 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA8$9.6 million0$0
Medical College of WisconsinMilwaukee, WI6$9 million0$0
Yale UniversityNew Haven, CT12$8.9 million0$0
Northwestern University at ChicagoChicago, IL6$7.9 million0$0
University of MinnesotaMinneapolis, MN7$7.9 million0$0
University of RochesterRochester, NY6$7.8 million0$0
University of ChicagoChicago, IL11$7 million0$0
SUNY at Stony BrookStony Brook, NY13$6.7 million0$0
Massachusetts Institute of TechnologyCambridge, MA6$6.5 million0$0
University of Alabama at BirminghamBirmingham, AL11$6.3 million0$0
Wayne State UniversityDetroit, MI6$6.3 million0$0
Emory UniversityAtlanta, GA8$6 million0$0
Medical University of South CarolinaCharleston, SC6$5.9 million0$0
Duke UniversityDurham, NC5$5.8 million0$0
Roswell Park Cancer Institute CorpBuffalo, NY6$5.8 million0$0
Weill Medical Coll of Cornell UnivNew York, NY12$5.8 million0$0
Van Andel Research InstituteGrand Rapids, MI5$5.3 million0$0
Mayo Clinic JacksonvilleJacksonville, FL7$5.2 million0$0
Georgetown UniversityWashington, DC8$5 million0$0
University of UtahSalt Lake City, UT7$4.9 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY4$4.9 million0$0
University of Miami School of MedicineCoral Gables, FL8$4.8 million0$0
SUNY at BuffaloAmherst, NY4$4.8 million0$0
University of California at DavisDavis, CA4$4.6 million0$0
University of California-IrvineIrvine, CA6$4.6 million0$0
University of Southern CaliforniaLos Angeles, CA3$4.4 million0$0
Baylor College of MedicineHouston, TX6$4.4 million0$0
Oregon State UniversityCorvallis, OR2$4.4 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA6$4.1 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ5$4.1 million0$0
Focal Medical, Inc.Cary, NC1$4 million0$0
Civatech Oncology, Inc.Morrisville, NC1$4 million0$0
Proda Biotech, LLCMarietta, GA1$4 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA5$4 million0$0
University of WashingtonSeattle, WA2$3.8 million0$0
Case Western Reserve UniversityCleveland, OH4$3.7 million0$0
University of Maryland, College ParkCollege Park, MD2$3.6 million0$0
University of IowaIowa City, IA3$3.5 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA2$3.4 million0$0
Marker Therapeutics, Inc.Houston, TX2$3.3 million0$0
Leukogene Therapeutics, Inc.Charleston, SC3$3.3 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA2$3.3 million0$0
Purdue UniversityWest Lafayette, IN4$3.2 million0$0
University of North Carolina at CharlotteCharlotte, NC4$3.1 million0$0
Providence Portland Medical CenterPortland, OR3$3.1 million0$0
University of CincinnatiCincinnati, OH4$3.1 million0$0
BCN Biosciences, LLCPasadena, CA1$3 million0$0
Virginia Commonwealth UniversityRichmond, VA4$3 million0$0
Albert Einstein College of MedicineBronx, NY3$3 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL2$3 million0$0
Rockefeller UniversityNew York, NY1$2.7 million0$0
Henry Ford Health SystemDetroit, MI2$2.7 million0$0
Boston Children's HospitalBoston, MA2$2.5 million0$0
Kaiser Foundation Research InstituteOakland, CA1$2.5 million0$0
University of Texas at El PasoEl Paso, TX3$2.4 million0$0
Dartmouth CollegeHanover, NH3$2.4 million0$0
Brigham and Women's HospitalBoston, MA1$2.4 million0$0
Tulane University of LouisianaNew Orleans, LA1$2.4 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH2$2.3 million0$0
Wistar InstitutePhiladelphia, PA3$2.3 million0$0
Methodist Hospital Research InstituteHouston, TX2$2.3 million0$0
Mayo Clinic ArizonaScottsdale, AZ2$2.1 million0$0
Thetis Pharmaceuticals, LLCDeep River, CT1$2.1 million0$0
The University of Texas Rio Grande ValleyEdinburg, TX3$2.1 million0$0
University of ArizonaTucson, AZ4$2.1 million0$0
Fred Hutchinson Cancer Research CenterSeattle, WA7$2.1 million0$0
Henry Ford Health + Michigan State University Health SciencesEast Lansing, MI4$2 million0$0
University of Oklahoma Norman CampusNorman, OK2$2 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025467$223,116,4600$0
2024513$219,332,6180$0
2023503$217,636,9100$0
2022483$204,377,0800$0
2021473$200,118,6610$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 14 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 5 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 2 awards here
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)PAR-27-089NIH93.396November 2, 2026Not listedSame assistance listing 93.396 as 241 awards here
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)PAR-27-088NIH93.396November 20, 2026Not listedSame assistance listing 93.396 as 241 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.396December 4, 2026Not listedSame assistance listing 93.396 as 241 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.396January 7, 2027$375,000Same assistance listing 93.396 as 241 awards here
Population Approaches to Reducing Alcohol-related Cancer Risk (R01 Clinical Trial Optional)PAR-25-221NIH93.396January 7, 2027Not listedSame assistance listing 93.396 as 241 awards here
Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)PAR-27-009NIH93.396January 25, 2027Not listedSame assistance listing 93.396 as 241 awards here
Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)RFA-CA-28-013NIH93.396February 9, 2027$700,000Same assistance listing 93.396 as 241 awards here
New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)PAR-25-272NIH93.396May 7, 2027Not listedSame assistance listing 93.396 as 241 awards here
New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)PAR-25-279NIH93.396May 7, 2027Not listedSame assistance listing 93.396 as 241 awards here
Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)RFA-CA-28-003NIH93.396June 11, 2027$600,000Same assistance listing 93.396 as 241 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIH93.396July 17, 2027Not listedSame assistance listing 93.396 as 241 awards here
Investigator-Focused Award (Parent R35)PAR-28-037NIH93.396October 4, 2027Not listedSame assistance listing 93.396 as 241 awards here
Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)RFA-CA-27-019NIH93.396October 19, 2027$300,000Same assistance listing 93.396 as 241 awards here
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)PA-25-301NIH93.396January 7, 2028Not listedSame assistance listing 93.396 as 241 awards here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)PA-25-304NIH93.396January 7, 2028Not listedSame assistance listing 93.396 as 241 awards here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)PA-25-306NIH93.396January 7, 2028Not listedSame assistance listing 93.396 as 241 awards here
Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)PAR-24-311NIH93.396January 7, 2028$500,000Same assistance listing 93.396 as 241 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.