Data / Environmental compliance / Pharmaceutical and Medicine Manufacturing
Pharmaceutical and Medicine Manufacturing: 162 facilities
Updated November 7, 2026. Source: US EPA, Enforcement and Compliance History Online (ECHO).
EPA's ECHO database lists 162 facilities in Pharmaceutical and Medicine Manufacturing (NAICS 3254) with a formal enforcement action, penalties of $5,000 or more, three or more quarters in significant noncompliance or a federal case in the five years to November 1, 2026: 243 formal actions, 197 informal actions and $11,453,977 in penalties.
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- Industry
- NAICS 3254, Pharmaceutical and Medicine Manufacturing
- Facilities
- 162
- Formal enforcement actions
- 243
- Informal actions
- 197
- Penalties
- $11,453,977 ($2,259,934 from federal cases)
- Facilities with three or more quarters in significant noncompliance
- 45
By state
| State | Facilities | Formal actions | Penalties |
|---|---|---|---|
| Massachusetts | 5 | 11 | $4,356,280 |
| Colorado | 9 | 7 | $1,380,093 |
| Connecticut | 2 | 3 | $1,073,300 |
| Georgia | 2 | 3 | $764,000 |
| New Jersey | 44 | 65 | $732,920 |
| South Carolina | 3 | 5 | $540,500 |
| Pennsylvania | 16 | 26 | $422,935 |
| Missouri | 4 | 7 | $411,582 |
| New York | 11 | 20 | $325,949 |
| Virginia | 4 | 8 | $284,872 |
| California | 5 | 9 | $275,153 |
| Iowa | 2 | 2 | $196,270 |
| Michigan | 3 | 3 | $127,796 |
| Wisconsin | 2 | 4 | $117,500 |
| Maryland | 7 | 9 | $82,482 |
| Delaware | 2 | 2 | $66,080 |
| Florida | 4 | 4 | $63,532 |
| Texas | 2 | 3 | $53,413 |
| Puerto Rico | 6 | 9 | $52,200 |
| Indiana | 5 | 10 | $28,900 |
| Mississippi | 2 | 2 | $25,250 |
| Idaho | 1 | 1 | $24,600 |
| Tennessee | 4 | 4 | $17,140 |
| North Carolina | 3 | 7 | $15,210 |
| Arkansas | 1 | 2 | $7,620 |
| Ohio | 3 | 5 | $7,600 |
| Oregon | 1 | 2 | $800 |
| Illinois | 2 | 2 | $0 |
| Minnesota | 2 | 3 | $0 |
| Oklahoma | 1 | 1 | $0 |
| Rhode Island | 1 | 1 | $0 |
| Utah | 1 | 1 | $0 |
| Washington | 1 | 2 | $0 |
| West Virginia | 1 | 0 | $0 |
Facilities with the largest penalties
Ranked by penalties of the last five years. Each row links to EPA's facility report.
| Facility | City | State | Formal actions | Penalties | Quarters in significant noncompliance | Latest penalty | Source |
|---|---|---|---|---|---|---|---|
| Nitto Denko Avecia | Milford | MA | 3 | $2,576,667 | 6 | February 5, 2026 | echo.epa.gov |
| Bostomatic | Milford | MA | 2 | $1,717,778 | 6 | February 5, 2026 | echo.epa.gov |
| LP Ind LLC, Jordan Process | Springfield Area | CO | 1 | $1,012,875 | 0 | March 2, 2026 | echo.epa.gov |
| Glanbia Nutritionals (na) Inc. | West Haven | CT | 1 | $1,000,000 | 9 | October 29, 2025 | echo.epa.gov |
| Corbion | Tucker | GA | 3 | $764,000 | 12 | September 16, 2024 | echo.epa.gov |
| PL Developments, Tank Farm | Piedmont | SC | 3 | $525,000 | 7 | September 22, 2025 | echo.epa.gov |
| Plaze, Incorporated | Pacific | MO | 3 | $411,582 | 12 | September 30, 2024 | echo.epa.gov |
| KS JV LLC | Denver | CO | 1 | $270,646 | 3 | January 12, 2024 | echo.epa.gov |
| DCW Casing LLC | Oelwein | IA | 2 | $196,270 | 4 | June 30, 2025 | echo.epa.gov |
| DSM Nutritional Products, Inc. | Belvidere | NJ | 2 | $168,375 | 0 | March 7, 2025 | echo.epa.gov |
| Novo Nordisk Pharmaceutical Industries LP | Petersburg | VA | 2 | $160,000 | 0 | November 5, 2025 | echo.epa.gov |
| Hovione LLC | East Windsor | NJ | 1 | $150,000 | 0 | July 3, 2026 | echo.epa.gov |
| Sanofi Pasteur/swiftwater Fac | Swiftwater | PA | 1 | $125,973 | 0 | November 28, 2023 | echo.epa.gov |
| Pharmacia & Upjohn (p&u), Kapi and Emu | Portage | MI | 2 | $119,696 | 0 | June 5, 2024 | echo.epa.gov |
| Piramal Critical Care Inc/hanover TWP | Bethlehem | PA | 2 | $116,062 | 0 | April 19, 2022 | echo.epa.gov |
| Polypeptide Laboratories Inc. | Torrance | CA | 2 | $114,944 | 0 | July 10, 2023 | echo.epa.gov |
| Ohm Laboratories Inc. North Brunswick Facilit | North Brunswick | NJ | 2 | $109,740 | 0 | September 15, 2026 | echo.epa.gov |
| Siegfried USA, LLC | Pennsville | NJ | 3 | $107,980 | 0 | December 2, 2024 | echo.epa.gov |
| Unither Manufacturing LLC | Rochester | NY | 3 | $95,900 | 8 | September 9, 2025 | echo.epa.gov |
| Granules Pharmaceuticals, Inc. | Chantilly | VA | 3 | $95,872 | 0 | May 30, 2023 | echo.epa.gov |
| Ecometics Inc | Norwalk | CT | 2 | $73,300 | 0 | September 18, 2024 | echo.epa.gov |
| Timecap Labs Inc | Farmingdale | NY | 2 | $73,200 | 2 | February 29, 2024 | echo.epa.gov |
| Beckman Coulter Inc | Hialeah | FL | 2 | $63,532 | 0 | May 22, 2023 | echo.epa.gov |
| Noramco | Wilmington | DE | 1 | $58,580 | 2 | August 3, 2026 | echo.epa.gov |
| Abbott Labs LVS MFG Plant | Austin | TX | 2 | $53,413 | 0 | October 28, 2025 | echo.epa.gov |
| Clay-Park Labs., Inc.- Bx.,ny | Bronx | NY | 1 | $51,297 | 0 | September 27, 2022 | echo.epa.gov |
| Coating Place LLC | Verona | WI | 1 | $50,000 | 0 | March 9, 2022 | echo.epa.gov |
| Sciegen Pharmaceuticals Inc | Hauppauge | NY | 2 | $48,000 | 0 | June 22, 2023 | echo.epa.gov |
| Becton Dickinson | Sparks | MD | 2 | $46,182 | 0 | August 7, 2025 | echo.epa.gov |
| Frontida Biopharm, Inc | Philadelphia | PA | 6 | $44,314 | 4 | October 6, 2026 | echo.epa.gov |
| Epic Pharma LLC | Laurelton | NY | 1 | $40,996 | 0 | May 5, 2022 | echo.epa.gov |
| Leiters Health | Englewood | CO | 1 | $35,166 | 0 | May 5, 2023 | echo.epa.gov |
| Patheon Puerto Rico Inc (former Mova) | Manati | PR | 3 | $32,500 | 3 | December 18, 2025 | echo.epa.gov |
| Catalent Massachusetts LLC | Chelsea | MA | 2 | $32,150 | 5 | November 25, 2025 | echo.epa.gov |
| Sigmpharm Laboratories LLC | Bensalem | PA | 3 | $31,907 | 4 | April 27, 2026 | echo.epa.gov |
| Biospectra Inc | Bangor | PA | 2 | $27,500 | 0 | April 8, 2026 | echo.epa.gov |
| Ecogen Processing Campus | Delta | CO | 1 | $25,308 | 3 | October 31, 2022 | echo.epa.gov |
| MR Juice LLC Warehouse | Garden City | ID | 1 | $24,600 | 0 | March 14, 2023 | echo.epa.gov |
| Apg, Inc | Elkhart | IN | 3 | $24,000 | 0 | June 16, 2022 | echo.epa.gov |
| Fareva Richmond Incorporated | Richmond | VA | 1 | $22,750 | 0 | January 27, 2023 | echo.epa.gov |
| Quicksilver Scientific | Louisville | CO | 1 | $19,893 | 1 | December 12, 2023 | echo.epa.gov |
| Pharmasol Contract Development & Manufacturing | South Easton | MA | 2 | $19,835 | 2 | June 28, 2024 | echo.epa.gov |
| Natureplex | Olive Branch | MS | 1 | $17,750 | 0 | May 3, 2024 | echo.epa.gov |
| Merck Sharp & Dohme, Kenilworth | Kenilworth | NJ | 3 | $17,600 | 1 | March 18, 2026 | echo.epa.gov |
| Safc Inc | Madison | WI | 3 | $17,500 | 0 | December 16, 2024 | echo.epa.gov |
| Neolpharma, Inc | Caguas | PR | 3 | $15,000 | 0 | January 8, 2024 | echo.epa.gov |
| Pharmaceutics International, Inc. | Hunt Valley | MD | 1 | $15,000 | 0 | April 5, 2022 | echo.epa.gov |
| Synagro [philadelphia Renewable Bio-Fuels LLC] | University City (subdivision) | PA | 1 | $14,996 | 0 | April 6, 2026 | echo.epa.gov |
| Sofie Co. D/B/A Sofie | Totowa | NJ | 1 | $14,625 | 0 | June 25, 2025 | echo.epa.gov |
| Becton Dickinson | Sparks | MD | 2 | $12,612 | 0 | August 7, 2025 | echo.epa.gov |
| Merck & Co Inc | Whitehouse Station | NJ | 1 | $12,600 | 0 | December 31, 2022 | echo.epa.gov |
| KVK Tech, Inc. | Newtown | PA | 2 | $12,500 | 5 | April 7, 2022 | echo.epa.gov |
| Halo Pharmaceutical Inc | East Hanover | NJ | 2 | $12,250 | 0 | May 19, 2026 | echo.epa.gov |
| Sanofi | Ridgefield | NJ | 1 | $11,900 | 0 | September 26, 2025 | echo.epa.gov |
| Taro Pharmaceuticals USA Inc | Cranbury | NJ | 1 | $11,600 | 0 | December 12, 2025 | echo.epa.gov |
| Upm Pharmaceuticals, LLC | Bristol | TN | 2 | $10,500 | 0 | February 11, 2026 | echo.epa.gov |
| Akorn Inc | Amityville | NY | 1 | $10,306 | 4 | October 20, 2025 | echo.epa.gov |
| LTS Lakewood LLC | Lakewood | NJ | 2 | $10,000 | 1 | August 18, 2025 | echo.epa.gov |
| New England Biolabs | Ipswich | MA | 2 | $9,850 | 9 | January 14, 2026 | echo.epa.gov |
| Elkins-Sinn Inc. | Cherry Hill | NJ | 2 | $9,525 | 0 | November 14, 2025 | echo.epa.gov |
| Alcami Corporation | Wilmington | NC | 3 | $9,360 | 3 | July 23, 2025 | echo.epa.gov |
| Copperhead Chemical Co Inc | Tamaqua | PA | 1 | $9,050 | 0 | April 7, 2022 | echo.epa.gov |
| KVK Tech Inc/ Terry DR | Newtown | PA | 1 | $8,620 | 0 | October 13, 2022 | echo.epa.gov |
| Lockheed Martin Comm Space Sys Lmcss | Newtown | PA | 1 | $8,620 | 0 | October 13, 2022 | echo.epa.gov |
| PL Developments LLC | Piedmont | SC | 1 | $8,500 | 0 | June 22, 2026 | echo.epa.gov |
| Nexgen Pharma | Colorado Springs | CO | 1 | $8,344 | 2 | November 17, 2025 | echo.epa.gov |
| Digestive Care, Inc. | Bethlehem | PA | 1 | $8,000 | 3 | September 24, 2025 | echo.epa.gov |
| Avista Pharma Solutions DBA Cambrex | Longmont | CO | 1 | $7,861 | 2 | September 18, 2026 | echo.epa.gov |
| Vantive US Healthcare LLC | Mountain Home | AR | 2 | $7,620 | 0 | November 21, 2025 | echo.epa.gov |
| MSN Pharmaceuticals Inc | Piscataway | NJ | 2 | $7,600 | 1 | May 29, 2026 | echo.epa.gov |
| Api Inc | Fairfield | NJ | 1 | $7,600 | 0 | March 30, 2022 | echo.epa.gov |
| Uspl Nutritionals LLC | North Brunswick | NJ | 1 | $7,600 | 0 | November 27, 2023 | echo.epa.gov |
| Spi Pharma Inc | Lewes | DE | 1 | $7,500 | 3 | March 22, 2024 | echo.epa.gov |
| GCP Laboratories | Gulfport | MS | 1 | $7,500 | 0 | August 18, 2026 | echo.epa.gov |
| Aurolife Pharma LLC | Dayton | NJ | 2 | $7,200 | 1 | December 29, 2025 | echo.epa.gov |
| Bostal LLC | Edison | NJ | 3 | $7,160 | 0 | June 18, 2025 | echo.epa.gov |
| Appco Pharma LLC | Piscataway | NJ | 2 | $7,125 | 1 | August 7, 2023 | echo.epa.gov |
| Guardian Drug Co | Dayton | NJ | 2 | $7,125 | 0 | March 4, 2022 | echo.epa.gov |
| Oakwood Products Inc Estill Facility | Estill | SC | 1 | $7,000 | 0 | March 6, 2025 | echo.epa.gov |
| Merck West Point Building B50 | Upper Gwynedd Township | PA | 1 | $6,400 | 0 | April 11, 2025 | echo.epa.gov |
| Janssen Biotech Inc | Malvern | PA | 1 | $5,857 | 0 | May 19, 2023 | echo.epa.gov |
| Fujifilm Diosynth Biotechnologies U.S.A., Inc. | Research Triangle Park | NC | 4 | $5,850 | 4 | August 5, 2025 | echo.epa.gov |
| Luxottica Optical Manufacturing-Memphis | Memphis | TN | 1 | $5,140 | 3 | July 24, 2025 | echo.epa.gov |
| Hikma Pharmaceuticals USA Inc. (0125041763) | Columbus | OH | 2 | $4,400 | 3 | May 21, 2025 | echo.epa.gov |
| Natural Organics Laboratories, Inc. | Amityville | NY | 5 | $3,750 | 0 | June 26, 2024 | echo.epa.gov |
| Catalent Pharma Solutions | Somerset | NJ | 1 | $3,600 | 0 | June 8, 2023 | echo.epa.gov |
| Cmic Cmo USA | Cranbury | NJ | 1 | $3,600 | 0 | November 24, 2021 | echo.epa.gov |
| Janssen Pharmaceuticals Companies of J&J | Titusville | NJ | 1 | $3,600 | 0 | April 7, 2026 | echo.epa.gov |
| Metropolitan Dermatology | Elizabeth | NJ | 1 | $3,500 | 0 | October 30, 2023 | echo.epa.gov |
| Metaugus Npri | Bloomington | IN | 2 | $3,400 | 0 | July 20, 2022 | echo.epa.gov |
| Alvogen Inc | Pine Brook | NJ | 1 | $3,375 | 0 | January 3, 2025 | echo.epa.gov |
| Leading Pharma | Fairfield | NJ | 1 | $3,375 | 0 | April 29, 2024 | echo.epa.gov |
| Minaris Regenerative Medicine | Allendale | NJ | 1 | $3,375 | 0 | December 6, 2024 | echo.epa.gov |
| American Regent Inc | New Albany | OH | 2 | $3,200 | 3 | February 4, 2026 | echo.epa.gov |
| Raritan Pharmaceuticals Inc | East Brunswick | NJ | 2 | $3,150 | 2 | October 20, 2025 | echo.epa.gov |
| Grant Industries Inc | Elmwood Park | NJ | 1 | $3,000 | 0 | March 6, 2023 | echo.epa.gov |
| Cerovene Inc | Valley Cottage | NY | 3 | $2,500 | 0 | July 22, 2022 | echo.epa.gov |
| Chartwell Pharmaceuticals | West Caldwell | NJ | 3 | $2,500 | 0 | July 19, 2022 | echo.epa.gov |
| Edenbridge Pharmaceuticals, LLC | Parsippany | NJ | 3 | $2,500 | 0 | February 28, 2022 | echo.epa.gov |
| Solaris Pharma Corp | Bridgewater | NJ | 3 | $2,500 | 0 | July 28, 2022 | echo.epa.gov |
By program
| Program | Facilities | Formal actions | Informal actions | Penalties | Facilities with quarters in significant noncompliance |
|---|---|---|---|---|---|
| Clean Air Act | 86 | 62 | 57 | $3,138,677 | 3 |
| Clean Water Act | 80 | 12 | 41 | $151,753 | 14 |
| Hazardous waste (RCRA) | 148 | 122 | 79 | $5,902,613 | 45 |
| Drinking water (SDWA) | 4 | 1 | 19 | $0 | 0 |
Public domain (U.S. government work). Counts and penalties cover the five years to November 1, 2026 as ECHO publishes them in its exporter and case downloads, drawn from EPA's air, water, hazardous waste and drinking water systems and from the states that report to them. Records can be incomplete, late or corrected after this page was read. A federal case penalty that names several facilities is shown on each of them and counted once in industry, state and national totals. Each row links to EPA's own report. A quarter in significant noncompliance is EPA's term for a serious violation status in a program, not a finding of fault beyond that status. This page uses US EPA data and is not endorsed or certified by the US EPA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.