Data / Drug companies / Oxymetazoline hydrochloride
Oxymetazoline hydrochloride: 64 companies and 158 products in the FDA NDC directory
Updated November 6, 2026. Source: US Food and Drug Administration, National Drug Code Directory (openFDA).
Oxymetazoline hydrochloride is listed in the FDA National Drug Code Directory by 64 companies, with 158 products in commercial distribution. 1 of the products (0.6%) are marketed under an abbreviated new drug application (ANDA), the generic route. The most common dosage forms are spray; spray, metered; cream, and the newest product started marketing on October 31, 2026.
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- Companies listing it
- 64
- Products
- 158
- Generic (ANDA) products
- 1 (0.6%)
- Application numbers
- 4
- Routes
- Nasal, Topical
- Brand names
- Nasal, Foster and Thrive Nasal, Major Nasal Decongestant, Afrin Original, Good Sense Nasal, Nasal Decongestant, Rhofade, Nasal
- openFDA record search
- api.fda.gov
Companies that list oxymetazoline hydrochloride
Ranked by number of products. Finished drugs in commercial distribution.
| Company | Products | Main dosage forms | Main marketing category | Newest product started |
|---|---|---|---|---|
| Bayer HealthCare LLC. | 12 | spray, metered; spray | Over the counter monograph drugs | April 19, 2024 |
| Procter & Gamble Manufacturing GmbH | 8 | spray | Over the counter monograph drugs | February 27, 2026 |
| Chain Drug Marketing Association | 6 | spray; solution | Over the counter monograph drugs | March 15, 2021 |
| Safeway | 6 | spray; spray, metered | Over the counter monograph drugs | February 27, 2026 |
| Amazon.com Services LLC | 5 | spray; spray, metered | Over the counter monograph drugs | September 24, 2026 |
| Discount Drug Mart | 5 | spray | Over the counter monograph drugs | May 22, 2019 |
| Dolgencorp, Inc. (dollar General & Rexall) | 5 | spray; spray, metered | Over the counter monograph drugs | September 30, 2020 |
| Valu Merchandisers Company | 5 | spray | Over the counter monograph drugs | May 22, 2019 |
| CVS Pharmacy | 4 | spray | Over the counter monograph drugs | August 29, 2022 |
| Chain Drug Marketing Association, Inc. | 4 | spray | Over the counter monograph drugs | July 1, 2025 |
| Lil' Drug Store Products, Inc. | 4 | spray | Over the counter monograph drugs | June 24, 2021 |
| Rite Aid Corporation | 4 | spray, metered; spray | Over the counter monograph drugs | December 5, 2018 |
| A-S Medication Solutions | 3 | spray | Over the counter monograph drugs | December 31, 2023 |
| Amerisource Bergen | 3 | spray | Over the counter monograph drugs | June 23, 2025 |
| HyVee Inc | 3 | spray | Over the counter monograph drugs | February 25, 2026 |
| Kenvue Brands LLC | 3 | spray | Over the counter monograph drugs | June 16, 2025 |
| Neilmed Pharmaceuticals Inc. | 3 | spray | Over the counter monograph drugs | October 1, 2022 |
| NuCare Pharmaceuticals,Inc. | 3 | spray | Over the counter monograph drugs | December 31, 2023 |
| Publix Super Markets, Inc | 3 | spray | Over the counter monograph drugs | May 16, 2019 |
| Reckitt Benckiser LLC | 3 | solution | Over the counter monograph drugs | November 1, 2018 |
| Topco Associates LLC | 3 | spray; spray, metered | Over the counter monograph drugs | July 17, 2018 |
| WinCo Foods, LLC | 3 | spray | Over the counter monograph drugs | August 2, 2018 |
| American Sales Company | 2 | spray | Over the counter monograph drugs | August 31, 2016 |
| Bi-Mart | 2 | spray | Over the counter monograph drugs | August 1, 2025 |
| CVS Pharmacy | 2 | spray | Over the counter monograph drugs | April 21, 2015 |
| Cardinal Health 110, LLC. DBA Leader | 2 | spray | Over the counter monograph drugs | May 30, 2024 |
| Church & Dwight Co., Inc. | 2 | spray | Over the counter monograph drugs | February 28, 2022 |
| Family Dollar (family Wellness) | 2 | spray | Over the counter monograph drugs | May 1, 2026 |
| H E B | 2 | spray | Over the counter monograph drugs | June 11, 2021 |
| Kroger Company | 2 | spray | Over the counter monograph drugs | May 27, 2026 |
| L. Perrigo Company | 2 | spray | Over the counter monograph drugs | January 8, 2026 |
| Major Pharmaceuticals | 2 | spray | Over the counter monograph drugs | December 31, 2023 |
| Meijer Distribution Inc | 2 | spray | Over the counter monograph drugs | November 20, 2018 |
| Preferred Pharmaceuticals Inc. | 2 | spray | Over the counter monograph drugs | June 9, 2026 |
| Sportpharm LLC | 2 | spray | Over the counter monograph drugs | February 7, 2026 |
| Strategic Sourcing Services LLC | 2 | spray; spray, metered | Over the counter monograph drugs | October 18, 2023 |
| Sun Pharmaceutical Industries, Inc. | 2 | cream; spray | Generic drugs (ANDA) | July 15, 2026 |
| United Exchange Corp. | 2 | spray | Over the counter monograph drugs | June 30, 2013 |
| United Natural Foods, Inc. DBA Unfi | 2 | spray | Over the counter monograph drugs | July 3, 2016 |
| Wal-Mart Stores Inc | 2 | spray | Over the counter monograph drugs | August 21, 2017 |
| Army and Air Force Exchange Service | 1 | spray | Over the counter monograph drugs | October 28, 2011 |
| Bjwc | 1 | spray, metered | Over the counter monograph drugs | June 4, 2021 |
| DR. Friedman's No More Nosebleed Kit Inc. | 1 | liquid | Over the counter monograph drugs | June 8, 2019 |
| Epi Health, LLC | 1 | cream | New drug applications (NDA) | January 18, 2021 |
| Foundation Consumer Brands | 1 | spray | Over the counter monograph drugs | August 17, 2021 |
| Genomma Lab USA | 1 | liquid | Over the counter monograph drugs | February 12, 2025 |
| Guangzhou ChuanMa International Trading Co.,Ltd. | 1 | spray | Over the counter monograph drugs | October 31, 2026 |
| H E B | 1 | spray | Over the counter monograph drugs | April 4, 2025 |
| Infirst Healthcare Inc. | 1 | spray | Over the counter monograph drugs | August 6, 2026 |
| Insight Pharmaceuticals LLC | 1 | spray, metered | Over the counter monograph drugs | June 8, 2009 |
| JC World Bell Wholesale Co., Inc. | 1 | spray | Over the counter monograph drugs | November 16, 2022 |
| Kroger Company | 1 | spray | Over the counter monograph drugs | April 5, 2024 |
| Marc Glassman, Inc. | 1 | spray | Over the counter monograph drugs | May 16, 2019 |
| Mayne Pharma | 1 | cream | New drug applications (NDA) | July 15, 2026 |
| Mayne Pharma Inc. | 1 | cream | New drug applications (NDA) | October 24, 2024 |
| Meijer, Inc. | 1 | spray | Over the counter monograph drugs | June 30, 2025 |
| Navajo Manufacturing Company Inc. | 1 | spray | Over the counter monograph drugs | December 4, 2017 |
| Padagis Israel Pharmaceuticals Ltd | 1 | spray | Over the counter monograph drugs | December 5, 2005 |
| Prodose, Inc. | 1 | spray | Over the counter monograph drugs | September 3, 2025 |
| Reliable 1 Laboratories LLC | 1 | spray | Over the counter monograph drugs | May 4, 2026 |
| Tai Guk Pharm. Co., Ltd. | 1 | spray | Over the counter monograph drugs | July 31, 2019 |
| Target Corporation | 1 | spray | Over the counter monograph drugs | January 24, 2025 |
| Target Corporation | 1 | spray | Over the counter monograph drugs | August 12, 2009 |
| Walgreen Company | 1 | spray | Over the counter monograph drugs | September 28, 1995 |
Dosage forms
| Dosage form | Products | Share |
|---|---|---|
| Spray | 129 | 81.6% |
| Spray, metered | 18 | 11.4% |
| Cream | 4 | 2.5% |
| Solution | 4 | 2.5% |
| Liquid | 2 | 1.3% |
| Kit | 1 | 0.6% |
Marketing categories
| Marketing category | Products | Share |
|---|---|---|
| Over the counter monograph drugs | 154 | 97.5% |
| New drug applications (NDA) | 3 | 1.9% |
| Generic drugs (ANDA) | 1 | 0.6% |
Pharmacologic classes
| Class | Products |
|---|---|
| Vasoconstrictor | 157 |
CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.