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Data / Drug companies / N-methyl-D-aspartate Receptor Antagonist

N-methyl-D-aspartate Receptor Antagonist drugs: 7 drugs from 45 companies in the FDA NDC directory

Updated November 6, 2026. Source: US Food and Drug Administration, National Drug Code Directory (openFDA).

N-methyl-D-aspartate Receptor Antagonist is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 134 products in this class from 45 companies, covering 7 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on August 28, 2025.

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  • 45Companies
  • 134Products
  • 7Drugs by generic name

Drugs in the N-methyl-D-aspartate Receptor Antagonist class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Memantine hydrochloride10236
Memantine167
Memantine and donepezil73
Memantine hydrochloride and donepezil hydrochloride62
Memantine and donepezil hydrochlorides11
Memantine hcl11
Memantine hydrochloride oral11

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
Macleods Pharmaceuticals Limited9capsule, extended release; tabletGeneric drugs (ANDA)August 28, 2025
A-S Medication Solutions7tablet; tablet, film coatedGeneric drugs (ANDA)September 26, 2022
Amneal Pharmaceuticals LLC6capsule, extended release; tablet, film coatedGeneric drugs (ANDA)March 24, 2022
Lupin Pharmaceuticals, Inc.6capsule, extended release; tablet, film coatedGeneric drugs (ANDA)February 20, 2018
Vitruvias Therapeutics6capsule, extended releaseGeneric drugs (ANDA)July 16, 2025
Zydus Lifesciences Limited6capsule, extended release; tablet, film coatedGeneric drugs (ANDA)April 8, 2018
Bryant Ranch Prepack5tablet; tablet, film coatedGeneric drugs (ANDA)February 28, 2019
Allergan, Inc.4capsuleNew drug applications (NDA)July 18, 2016
Amneal Pharmaceuticals NY LLC4capsule, extended releaseGeneric drugs (ANDA)February 1, 2017
Aphena Pharma Solutions - Tennessee, LLC4tablet; tablet, film coatedGeneric drugs (ANDA)February 28, 2019
Aurobindo Pharma Limited4capsule, extended releaseGeneric drugs (ANDA)August 9, 2021
Bryant Ranch Prepack4tabletGeneric drugs (ANDA)February 28, 2019
Cardinal Health 107, LLC4tablet, film coated; tabletGeneric drugs (ANDA)July 20, 2015
Rising Pharma Holdings, Inc.4capsule, extended releaseGeneric drugs (ANDA)June 1, 2025
Slate Run Pharmaceuticals, LLC4capsule, extended releaseGeneric drugs (ANDA)November 15, 2021
Zydus Pharmaceuticals USA Inc.4capsule, extended releaseGeneric drugs (ANDA)April 8, 2018
Chartwell RX, LLC3tablet; solutionGeneric drugs (ANDA)July 11, 2018
Major Pharmaceuticals3tablet, film coated; capsule, extended releaseGeneric drugs (ANDA)February 20, 2018
NCS HealthCare of Ky, LLC DBA Vangard Labs3tablet; capsule, extended releaseGeneric drugs (ANDA)August 9, 2021
Actavis Pharma, Inc.2tabletAuthorized generics (NDA)April 1, 2015
Ajanta Pharma USA Inc.2tabletGeneric drugs (ANDA)August 27, 2015
Alembic Pharmaceuticals Inc.2tablet, coatedGeneric drugs (ANDA)October 13, 2015
Alembic Pharmaceuticals Limited2tablet, coatedGeneric drugs (ANDA)October 13, 2015
American Health Packaging2tabletGeneric drugs (ANDA)September 9, 2015
Amneal Pharmaceuticals of New York LLC2tablet, film coatedGeneric drugs (ANDA)April 30, 2015
Aurobindo Pharma Limited2tablet, film coatedGeneric drugs (ANDA)October 13, 2015
AvPAK2tablet, film coatedGeneric drugs (ANDA)February 20, 2024
Bryant Ranch Prepack2tabletGeneric drugs (ANDA)February 28, 2019
Camber Pharmaceuticals, Inc.2tabletGeneric drugs (ANDA)September 26, 2022
Carlsbad Technology, Inc.2tablet, film coatedGeneric drugs (ANDA)June 22, 2025
Direct_Rx2tabletGeneric drugs (ANDA)February 29, 2024
Dr. Reddy's Laboratories Limited2tablet, film coatedGeneric drugs (ANDA)July 11, 2015
NorthStar RxLLC2tabletGeneric drugs (ANDA)September 13, 2022
Sun Pharmaceutical Industries, Inc.2tablet, film coatedGeneric drugs (ANDA)July 11, 2015
Unichem Pharmaceuticals (USA), Inc.2tablet, film coatedGeneric drugs (ANDA)November 1, 2015
Upsher-Smith Laboratories, LLC2tablet, film coatedGeneric drugs (ANDA)July 31, 2015
Viona Pharmaceuticals Inc2tabletGeneric drugs (ANDA)February 28, 2019
Ani Pharmaceuticals, Inc.1capsule, extended releaseGeneric drugs (ANDA)January 1, 2025
Apotex Corp.1solutionGeneric drugs (ANDA)April 30, 2018
AvKARE1capsule, extended releaseGeneric drugs (ANDA)February 6, 2025
Chartwell Governmental & Specialty RX, LLC.1solutionGeneric drugs (ANDA)October 13, 2015
Coupler LLC1tabletGeneric drugs (ANDA)February 4, 2025
Preferred Pharmaceuticals Inc.1tabletGeneric drugs (ANDA)May 1, 2024
Remedyrepack Inc.1tabletGeneric drugs (ANDA)January 20, 2022
Seton Pharmaceuticals1solutionGeneric drugs (ANDA)August 31, 2020

Dosage forms

Dosage formProductsShare
Capsule, extended release4835.8%
Tablet4332.1%
Tablet, film coated3022.4%
Solution53.7%
Tablet, coated43%
Capsule43%

CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.