Data / Drug companies / N-methyl-D-aspartate Receptor Antagonist
N-methyl-D-aspartate Receptor Antagonist drugs: 7 drugs from 45 companies in the FDA NDC directory
Updated November 6, 2026. Source: US Food and Drug Administration, National Drug Code Directory (openFDA).
N-methyl-D-aspartate Receptor Antagonist is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 134 products in this class from 45 companies, covering 7 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on August 28, 2025.
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- 45Companies
- 134Products
- 7Drugs by generic name
Drugs in the N-methyl-D-aspartate Receptor Antagonist class
Ranked by number of companies that list the drug.
| Drug | Products here | Companies listing it |
|---|---|---|
| Memantine hydrochloride | 102 | 36 |
| Memantine | 16 | 7 |
| Memantine and donepezil | 7 | 3 |
| Memantine hydrochloride and donepezil hydrochloride | 6 | 2 |
| Memantine and donepezil hydrochlorides | 1 | 1 |
| Memantine hcl | 1 | 1 |
| Memantine hydrochloride oral | 1 | 1 |
Companies with the most products in this class
| Company | Products | Main dosage forms | Main marketing category | Newest product started |
|---|---|---|---|---|
| Macleods Pharmaceuticals Limited | 9 | capsule, extended release; tablet | Generic drugs (ANDA) | August 28, 2025 |
| A-S Medication Solutions | 7 | tablet; tablet, film coated | Generic drugs (ANDA) | September 26, 2022 |
| Amneal Pharmaceuticals LLC | 6 | capsule, extended release; tablet, film coated | Generic drugs (ANDA) | March 24, 2022 |
| Lupin Pharmaceuticals, Inc. | 6 | capsule, extended release; tablet, film coated | Generic drugs (ANDA) | February 20, 2018 |
| Vitruvias Therapeutics | 6 | capsule, extended release | Generic drugs (ANDA) | July 16, 2025 |
| Zydus Lifesciences Limited | 6 | capsule, extended release; tablet, film coated | Generic drugs (ANDA) | April 8, 2018 |
| Bryant Ranch Prepack | 5 | tablet; tablet, film coated | Generic drugs (ANDA) | February 28, 2019 |
| Allergan, Inc. | 4 | capsule | New drug applications (NDA) | July 18, 2016 |
| Amneal Pharmaceuticals NY LLC | 4 | capsule, extended release | Generic drugs (ANDA) | February 1, 2017 |
| Aphena Pharma Solutions - Tennessee, LLC | 4 | tablet; tablet, film coated | Generic drugs (ANDA) | February 28, 2019 |
| Aurobindo Pharma Limited | 4 | capsule, extended release | Generic drugs (ANDA) | August 9, 2021 |
| Bryant Ranch Prepack | 4 | tablet | Generic drugs (ANDA) | February 28, 2019 |
| Cardinal Health 107, LLC | 4 | tablet, film coated; tablet | Generic drugs (ANDA) | July 20, 2015 |
| Rising Pharma Holdings, Inc. | 4 | capsule, extended release | Generic drugs (ANDA) | June 1, 2025 |
| Slate Run Pharmaceuticals, LLC | 4 | capsule, extended release | Generic drugs (ANDA) | November 15, 2021 |
| Zydus Pharmaceuticals USA Inc. | 4 | capsule, extended release | Generic drugs (ANDA) | April 8, 2018 |
| Chartwell RX, LLC | 3 | tablet; solution | Generic drugs (ANDA) | July 11, 2018 |
| Major Pharmaceuticals | 3 | tablet, film coated; capsule, extended release | Generic drugs (ANDA) | February 20, 2018 |
| NCS HealthCare of Ky, LLC DBA Vangard Labs | 3 | tablet; capsule, extended release | Generic drugs (ANDA) | August 9, 2021 |
| Actavis Pharma, Inc. | 2 | tablet | Authorized generics (NDA) | April 1, 2015 |
| Ajanta Pharma USA Inc. | 2 | tablet | Generic drugs (ANDA) | August 27, 2015 |
| Alembic Pharmaceuticals Inc. | 2 | tablet, coated | Generic drugs (ANDA) | October 13, 2015 |
| Alembic Pharmaceuticals Limited | 2 | tablet, coated | Generic drugs (ANDA) | October 13, 2015 |
| American Health Packaging | 2 | tablet | Generic drugs (ANDA) | September 9, 2015 |
| Amneal Pharmaceuticals of New York LLC | 2 | tablet, film coated | Generic drugs (ANDA) | April 30, 2015 |
| Aurobindo Pharma Limited | 2 | tablet, film coated | Generic drugs (ANDA) | October 13, 2015 |
| AvPAK | 2 | tablet, film coated | Generic drugs (ANDA) | February 20, 2024 |
| Bryant Ranch Prepack | 2 | tablet | Generic drugs (ANDA) | February 28, 2019 |
| Camber Pharmaceuticals, Inc. | 2 | tablet | Generic drugs (ANDA) | September 26, 2022 |
| Carlsbad Technology, Inc. | 2 | tablet, film coated | Generic drugs (ANDA) | June 22, 2025 |
| Direct_Rx | 2 | tablet | Generic drugs (ANDA) | February 29, 2024 |
| Dr. Reddy's Laboratories Limited | 2 | tablet, film coated | Generic drugs (ANDA) | July 11, 2015 |
| NorthStar RxLLC | 2 | tablet | Generic drugs (ANDA) | September 13, 2022 |
| Sun Pharmaceutical Industries, Inc. | 2 | tablet, film coated | Generic drugs (ANDA) | July 11, 2015 |
| Unichem Pharmaceuticals (USA), Inc. | 2 | tablet, film coated | Generic drugs (ANDA) | November 1, 2015 |
| Upsher-Smith Laboratories, LLC | 2 | tablet, film coated | Generic drugs (ANDA) | July 31, 2015 |
| Viona Pharmaceuticals Inc | 2 | tablet | Generic drugs (ANDA) | February 28, 2019 |
| Ani Pharmaceuticals, Inc. | 1 | capsule, extended release | Generic drugs (ANDA) | January 1, 2025 |
| Apotex Corp. | 1 | solution | Generic drugs (ANDA) | April 30, 2018 |
| AvKARE | 1 | capsule, extended release | Generic drugs (ANDA) | February 6, 2025 |
| Chartwell Governmental & Specialty RX, LLC. | 1 | solution | Generic drugs (ANDA) | October 13, 2015 |
| Coupler LLC | 1 | tablet | Generic drugs (ANDA) | February 4, 2025 |
| Preferred Pharmaceuticals Inc. | 1 | tablet | Generic drugs (ANDA) | May 1, 2024 |
| Remedyrepack Inc. | 1 | tablet | Generic drugs (ANDA) | January 20, 2022 |
| Seton Pharmaceuticals | 1 | solution | Generic drugs (ANDA) | August 31, 2020 |
Dosage forms
| Dosage form | Products | Share |
|---|---|---|
| Capsule, extended release | 48 | 35.8% |
| Tablet | 43 | 32.1% |
| Tablet, film coated | 30 | 22.4% |
| Solution | 5 | 3.7% |
| Tablet, coated | 4 | 3% |
| Capsule | 4 | 3% |
CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.