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Data / Drug companies / Dihydrofolate Reductase Inhibitor Antibacterial

Dihydrofolate Reductase Inhibitor Antibacterial drugs: 7 drugs from 56 companies in the FDA NDC directory

Updated November 6, 2026. Source: US Food and Drug Administration, National Drug Code Directory (openFDA).

Dihydrofolate Reductase Inhibitor Antibacterial is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 124 products in this class from 56 companies, covering 7 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on July 9, 2026.

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  • 56Companies
  • 124Products
  • 7Drugs by generic name

Drugs in the Dihydrofolate Reductase Inhibitor Antibacterial class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Sulfamethoxazole and trimethoprim10348
Polymyxin b sulfate and trimethoprim sulfate77
Polymyxin b sulfate and trimethoprim66
Trimethoprim55
Sulfameth/trimeth-ds11
Sulfamethoxazole, trimethoprim11
Trimethoprim sulfate and polymyxin b sulfate11

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
A-S Medication Solutions20tablet; suspensionGeneric drugs (ANDA)September 13, 2010
Proficient Rx LP6tablet; solutionGeneric drugs (ANDA)September 13, 2010
Remedyrepack Inc.6tablet; solution/ dropsGeneric drugs (ANDA)July 1, 2025
Teva Parenteral Medicines, Inc.6injection, solution, concentrateGeneric drugs (ANDA)August 15, 2024
NuCare Pharmaceuticals,Inc.5tablet; solution/ dropsGeneric drugs (ANDA)February 16, 2010
Preferred Pharmaceuticals Inc.5suspension; solution/ dropsGeneric drugs (ANDA)March 14, 2024
Chartwell RX, LLC4suspension; tabletGeneric drugs (ANDA)January 25, 2007
Somerset Therapeutics, LLC4injection, solution, concentrate; solution/ dropsGeneric drugs (ANDA)August 6, 2024
Advanced Rx of Tennessee, LLC3tabletGeneric drugs (ANDA)September 13, 2010
Aurobindo Pharma Limited3tablet; suspensionGeneric drugs (ANDA)June 8, 2010
American Health Packaging2tablet; suspensionGeneric drugs (ANDA)November 7, 2024
Amneal Pharmaceuticals LLC2tabletGeneric drugs (ANDA)September 13, 2010
Amneal Pharmaceuticals of New York LLC2tabletGeneric drugs (ANDA)September 13, 2010
Ani Pharmaceuticals, Inc.2suspension; tabletGeneric drugs (ANDA)November 4, 2022
AvKARE2tabletGeneric drugs (ANDA)August 5, 2015
Cardinal Health 107, LLC2tabletGeneric drugs (ANDA)March 23, 2026
Cronus Pharma LLC2tabletGeneric drugs (ANDA)February 16, 2010
Northwind Health Company, LLC2tabletGeneric drugs (ANDA)March 23, 2023
NuCare Pharmaceuticals, Inc.2tabletGeneric drugs (ANDA)February 16, 2010
PD-Rx Pharmaceuticals, Inc.2tabletGeneric drugs (ANDA)February 16, 2010
Pai Holdings, LLC DBA Pai Pharma2suspensionNew drug applications (NDA)August 5, 2024
Rising Pharma Holdings, Inc.2tabletGeneric drugs (ANDA)February 16, 2010
Sportpharm LLC2tablet; solution/ dropsGeneric drugs (ANDA)February 16, 2010
Sun Pharmaceutical Industries, Inc2tabletNew drug applications (NDA)November 1, 2004
Sun Pharmaceutical Industries, Inc.2tabletGeneric drugs (ANDA)August 25, 1986
Vista Pharmaceuticals, Inc.2tabletGeneric drugs (ANDA)August 22, 2006
Asclemed USA, Inc.1tabletGeneric drugs (ANDA)February 16, 2010
Atlantic Biologicals Corp.1suspensionGeneric drugs (ANDA)October 4, 2017
AvPAK1tabletGeneric drugs (ANDA)September 23, 2014
Bausch & Lomb Incorporated1solution/ dropsGeneric drugs (ANDA)February 14, 1997
Bryant Ranch Prepack1tabletGeneric drugs (ANDA)September 13, 2010
Bryant Ranch Prepack1tabletGeneric drugs (ANDA)February 16, 2010
Chartwell Governmental & Specialty RX, LLC.1suspensionGeneric drugs (ANDA)January 24, 2007
Coupler LLC1tabletGeneric drugs (ANDA)May 11, 2026
Denton Pharma, Inc. DBA Northwind Pharmaceuticals1tabletGeneric drugs (ANDA)February 12, 2020
Direct RX1tabletGeneric drugs (ANDA)August 13, 2019
Dr. Reddy's Laboratories Inc.1tabletNew drug applications (NDA)January 30, 2024
Golden State Medical Supply, Inc.1tabletGeneric drugs (ANDA)August 25, 1986
Golden State Medical Supply, Inc.1tabletGeneric drugs (ANDA)October 28, 2022
Kesin Pharma Corporation1suspensionGeneric drugs (ANDA)July 5, 2022
Lupin Pharmaceuticals,Inc.1tabletGeneric drugs (ANDA)June 24, 2011
Major Pharmaceuticals1tabletGeneric drugs (ANDA)September 13, 2010
NCS HealthCare of Ky, LLC DBA Vangard Labs1tabletGeneric drugs (ANDA)February 16, 2010
Northwind Health Company, LLC1tabletGeneric drugs (ANDA)November 6, 2025
Novel Laboratories, Inc.1tabletGeneric drugs (ANDA)March 4, 2014
PharmPak, Inc.1tabletGeneric drugs (ANDA)July 11, 2019
Pharmasource Meds, LLC1tabletGeneric drugs (ANDA)February 28, 2023
Prasco Laboratories1suspensionGeneric drugs (ANDA)July 5, 2022
Proficient Rx LP1tabletGeneric drugs (ANDA)February 16, 2010
QPharma, Inc.1tabletGeneric drugs (ANDA)February 16, 2010
Quality Care Products, LLC1tabletGeneric drugs (ANDA)May 4, 2018
Redpharm Drug1tabletGeneric drugs (ANDA)September 13, 2010
Sandoz Inc1solutionGeneric drugs (ANDA)April 16, 1998
St. Mary's Medical Park Pharmacy1tabletGeneric drugs (ANDA)June 22, 2022
Unit Dose Solutions, Inc.1tabletGeneric drugs (ANDA)July 9, 2026
Verityrx, LLC1tabletGeneric drugs (ANDA)February 16, 2010

Dosage forms

Dosage formProductsShare
Tablet8669.4%
Suspension1512.1%
Injection, solution, concentrate97.3%
Solution75.6%
Solution/ drops75.6%

CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.