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Data / Research funding / Transplantation

Transplantation: 2,381 NIH awards ($2.9B) to 411 organizations

2,381 NIH awards ($2.9B) in the NIH spending category Transplantation, to 411 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 2,381 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Blood and Marrow Transplant Clinical Trials Network DCC- The Medical College of Wisconsin, Inc.NIHNational Heart, Lung, and Blood Institute2021 to 2025$36,418,175September 15, 2017August 31, 2031HAMADANI, MEHDI HUSSAINreporter.nih.gov
A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy ResearchNIHNational Cancer Institute2021 to 2025$30,268,190March 1, 1998February 29, 2028SHAW, BRONWENreporter.nih.gov
PPDs Application for the Transplantation Statistical and Clinical Coordinating Center (T-SCCC) (U01 Clinical Trial Not Allowed)NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$26,732,375June 12, 2023April 30, 2028SEVER, MICHELLE LYNNreporter.nih.gov
Expanding HOPE Liver Transplantation: Understanding Opportunistic Infection and Cancer RiskNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$18,807,472August 1, 2018August 31, 2030DURAND, CHRISTINE MARIEreporter.nih.gov
Assessment of Biomarker Guided CNI Substitution in Kidney TransplantationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$16,391,930July 1, 2025June 30, 2029HEEGER, PETER SCOTTreporter.nih.gov
Targeting Inflammation and Alloimmunity in Lung Transplant Recipients With ClazakizumabNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,471,597September 14, 2021June 30, 2028MADSEN, JOREN Creporter.nih.gov
Autologous chimeric antigen receptor engineered T cell immunotherapy for desensitization in patients awaiting kidney transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,843,451August 20, 2021May 31, 2028NAJI, ALIreporter.nih.gov
Lung Transplant Clinical Trial Network (LT-CTN)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,392,000June 1, 2025May 31, 2028PALMER, SCOTT Mreporter.nih.gov
Extracellular Vesicles for Gaining Insights into Tissue Senescent Signatures: A SenNET Pilot and Exploratory ProjectNIHNational Institute on Aging2021 to 2025$13,842,784September 30, 2021August 31, 2027KUCHEL, GEORGE Areporter.nih.gov
A Tolerance Approach to XenotransplantationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$13,161,555September 15, 2000December 31, 2026SYKES, MEGANreporter.nih.gov
The Duke Senescent Cell Evaluations in Normal Tissues (SCENT) Mapping CenterNIHNational Institute on Aging2021 to 2025$12,705,171September 30, 2021August 31, 2026NIXON, ANDREW B.reporter.nih.gov
Tissue and organ specific human B cell immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$12,146,380April 1, 2019March 31, 2025LUND, FRANCES E.reporter.nih.gov
Advancing brain health research through male germline editing in marmosetsNIHNational Institute on Drug Abuse2021 to 2025$12,061,296August 1, 2021May 31, 2027HERMANN, BRIAN PETERreporter.nih.gov
Human anti-viral immune responses in tissues and circulationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,930,741January 1, 2017February 28, 2027FARBER, DONNA L.reporter.nih.gov
Targeting the B Cell Response to Treat Antibody-Mediated RejectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,789,092August 20, 2021May 31, 2028KNECHTLE, STUART JOHNSTONreporter.nih.gov
Advancing Transplantation Outcomes in ChildrenNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$11,293,854July 1, 2025June 30, 2028BRISCOE, DAVID M.reporter.nih.gov
Utility of Biomarkers of Rejection and Kidney Injury in Tailoring Liver Transplant ImmunosuppressionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,920,671September 6, 2021June 30, 2028BOIKE, JUSTINreporter.nih.gov
Liver Cirrhosis Network: Scientific and Data Coordination CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$10,655,826August 28, 2021July 31, 2027SMITH, ABIGAILreporter.nih.gov
Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant candidates (COLT)NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$9,640,870August 26, 2021September 30, 2024LIMAYE, ABHIJIT PRAKASHreporter.nih.gov
Lung Transplant Consortium - Data Coordinating CenterNIHNational Heart, Lung, and Blood Institute2022 to 2025$9,634,917August 5, 2022July 31, 2027PALMER, SCOTT Mreporter.nih.gov
Human Nociceptor and Spinal Cord Molecular Signature CenterNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$9,264,871September 19, 2022August 31, 2027PRICE, THEODORE J.reporter.nih.gov
NIAID CLINICAL DATA AND SAFETY MANAGEMENT CENTER (CDSMC)NIHNational Institute of Allergy and Infectious Diseases2021$7,818,967September 15, 2021September 14, 2022MOLINA, DANIELreporter.nih.gov
Stanford Tissue Mapping CenterNIHNational Human Genome Research Institute2022 to 2025$7,785,758September 23, 2022June 30, 2026SNYDER, MICHAEL P.reporter.nih.gov
A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-Negative kidney recipients (THINKER-NEXT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,767,541April 15, 2021March 31, 2027SCHAUBEL, DOUGLAS EARLreporter.nih.gov
Parkinsons Disease Scalable iPSC Autologous Cell TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$7,528,144January 1, 2020December 31, 2025HALLETT, PENELOPE JANEreporter.nih.gov
Application of Progenitor Niche Signals to Ex Vivo NephrogenesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$7,389,413September 15, 2021June 30, 2027OXBURGH, LEIFreporter.nih.gov
Strategies to Optimize Pig-to-Primate Kidney Xenograft SurvivalNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$7,360,026July 1, 2016June 30, 2030ADAMS, ANDREW Breporter.nih.gov
TRANSPIRE: A Prospective Cohort Study of Lung Injury After Hematopoietic Stem Cell Transplant in Children.NIHNational Heart, Lung, and Blood Institute2021 to 2025$7,251,380September 1, 2021May 31, 2027DAVIES, STELLA MARGARETreporter.nih.gov
Biorepository and Coordinating Center for Studies on Cardiovascular Complications of Human Type 1 DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$7,099,019August 1, 2022May 31, 2027ATKINSON, MARK A.reporter.nih.gov
Long Term Follow up of the Lung Transplant Outcomes Group CohortNIHNational Heart, Lung, and Blood Institute2021 to 2025$7,078,569June 15, 2019May 31, 2027CHRISTIE, JASON Dreporter.nih.gov
Overcoming Barriers to retinal ganglion cell replacement in experimental glaucomaNIHNational Eye Institute2021 to 2025$7,031,142September 30, 2021July 31, 2027MEYER, JASON STEPHENreporter.nih.gov
Exosomes as mediators of cardiac injury and repairNIHNational Heart, Lung, and Blood Institute2021 to 2025$7,022,243September 1, 2017June 30, 2029KISHORE, RAJreporter.nih.gov
Personalized prime editing as a platform for hepatic inborn errors of metabolismNIHNational Center for Advancing Translational Sciences2024 to 2025$6,886,793September 20, 2024August 31, 2028AHRENS-NICKLAS, REBECCA CLAREreporter.nih.gov
Subcutaneous Drug Development for Portal Hypertension AscitesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$6,758,500September 22, 2014July 31, 2027CASTILLO, GERARDO M.reporter.nih.gov
The spectrum of cognitive impairment including Alzheimer’s Disease and Related Dementias after liver transplantationNIHNational Institute on Aging2021 to 2025$6,330,805June 15, 2018May 31, 2028LAI, JENNIFER C.reporter.nih.gov
Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant candidates (COLT)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$5,882,740August 26, 2021May 31, 2028LIMAYE, ABHIJIT PRAKASHreporter.nih.gov
Novel Biologic Therapies for GVHDNIHNational Heart, Lung, and Blood Institute2021 to 2025$5,851,412February 1, 2010June 30, 2026KEAN, LESLIE Sreporter.nih.gov
Descemet Endothelial Thickness Comparison Trial (DETECT)NIHNational Eye Institute2021 to 2025$5,663,165April 1, 2021March 31, 2027ROSE-NUSSBAUMER, JENNIFERreporter.nih.gov
A Randomized Trial of Fistula vs. Graft Arteriovenous Vascular Access in Older Adults with End-Stage Kidney Disease on Hemodialysis: The AV ACCESS TrialNIHNational Institute on Aging2021 to 2025$5,580,574September 1, 2021August 31, 2027MUREA, MARIANAreporter.nih.gov
THE NNTC COLLECTS, STORE, AND PROVIDE CLINICAL DATA AND WELL CHARACTERIZED BIOLOGICAL SPECIMENS, INCLUDING POST-MORTEM TISSUE FROM STUDY VOLUNTEERS AND/OR ORGAN DONORS WITH HIV AS WELL AS HIV-NEGATIVENIHNational Institute of Mental Health2023 to 2025$5,429,596August 23, 2025August 22, 2026MOORE, DAVID Jreporter.nih.gov
Kidney Transplantation from Donors with HIV: Impact on Rejection and Long-term OutcomesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$5,224,210May 25, 2023April 30, 2028DURAND, CHRISTINE MARIEreporter.nih.gov
A Randomized Controlled Trial of Prophylaxis with Direct-acting Antivirals for Kidney Transplantation from Hepatitis C virus-infected donor to Uninfected Recipients (PREVENT-HCV)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,162,956March 25, 2022February 28, 2027DURAND, CHRISTINE MARIEreporter.nih.gov
Safety and efficacy of Belatacept in heart transplantationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$5,158,955June 6, 2023March 31, 2028HABAL, MARLENAreporter.nih.gov
Fecal Microbiota Transplantation and Fiber for the Treatment of Graft-versus-host Disease After Hematopoietic Cell TransplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$5,128,451September 1, 2023June 30, 2027FREDRICKS, DAVID NEALreporter.nih.gov
Novel Strategies to Improve Blood Transfusion PracticeNIHNational Heart, Lung, and Blood Institute2024 to 2025$5,119,758August 15, 2022July 31, 2027LUO, HONGBO Rreporter.nih.gov
Comparison of High vs. Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$5,116,475June 9, 2023March 31, 2028HALASA, NATASHA BASSAMreporter.nih.gov
Human gene transfer & macrophage cell transplantation therapy of hereditary PAP (hPAP)NIHNational Heart, Lung, and Blood Institute2023 to 2025$5,061,587May 10, 2021April 30, 2027TRAPNELL, BRUCE Creporter.nih.gov
Composite porcine islet-kidney xenotransplants to cure diabetes and renal failureNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,035,116May 21, 2020April 30, 2026SACHS, DAVID Hreporter.nih.gov
Mucus-degrading intestinal bacteria and toxicities of hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2024 to 2025$5,032,505September 21, 2024July 31, 2029JENQ, ROBERTreporter.nih.gov
1/2A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation with Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients with Severe Aplastic AnemiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$5,023,972April 1, 2022March 31, 2029SHAW, BRONWENreporter.nih.gov
14/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Scientific Data Research CenterNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$4,865,046September 25, 2017May 31, 2028FREEDMAN, BARRY IRAreporter.nih.gov
Investigating the heterogeneity and coordination of hematopoietic stem cellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,840,269August 1, 2020July 31, 2027LU, RONGreporter.nih.gov
Program to promote lung regeneration and block fibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,819,926February 15, 2020February 14, 2026CHAPMAN, HAROLD Areporter.nih.gov
Novel Stem Cell Immunotherapy for MDR-TuberculosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,800,190June 4, 2021May 31, 2026JAGANNATH, CHINNASWAMYreporter.nih.gov
HOPE in Action: A clinical trial of HIV-to-HIV deceased donor kidney transplantationNIHNational Institute of Allergy and Infectious Diseases2021$4,782,581August 31, 2021July 31, 2023DURAND, CHRISTINE MARIEreporter.nih.gov
A Phase I Clinical Trial Testing Feasibility of Hematopoietic Stem Cell Gene Therapy Using Platelet Factor VIII to Safely Improve Hemostasis for Severe Hemophilia A with Inhibitory AntibodiesNIHNational Heart, Lung, and Blood Institute2021 to 2023$4,780,411April 5, 2019March 31, 2026WILCOX, DAVID ALLENreporter.nih.gov
Transplanting Lungs from Uncontrolled Donation after Circulatory DeathNIHNational Heart, Lung, and Blood Institute2024 to 2025$4,714,267July 8, 2022June 30, 2027WALL, STEPHEN Preporter.nih.gov
Bcl-2 and Mcl-1 inhibition for induction of hematopoietic chimerism and renal allograft tolerance without myelosuppression in nonhuman primatesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,613,595June 3, 2022May 31, 2027KAWAI, TATSUOreporter.nih.gov
Diabetes Endothelial Keratoplasty Study: Impact of Diabetes on Corneal Transplant Success and Cell LossNIHNational Eye Institute2021 to 2025$4,496,381May 1, 2021April 30, 2026GAL, ROBIN Lreporter.nih.gov
Targeting Inflammation and Alloimmunity in Heart Transplant Recipients with TocilizumabNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$4,466,979May 1, 2018April 30, 2025MADSEN, JOREN Creporter.nih.gov
A nonhuman primate model of stem cell transplantation to understand determinants of post-transplant SIV clearanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,411,202December 21, 2016June 30, 2026SACHA, JONAH B.reporter.nih.gov
Cell-cell interactions governing lung epithelial progenitor cellsNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,407,300March 15, 2020January 31, 2027KIM, CARLA F.reporter.nih.gov
Neonatal porcine islet xenografts for the treatment of type 1 diabetesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,363,576September 1, 2010June 30, 2025KIRK, ALLAN D.reporter.nih.gov
Charting human islet maturation via combined soft nanoelectronics and single-cell spatial transcriptomicsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$4,276,659September 17, 2021May 31, 2027LIU, JIAreporter.nih.gov
CD11b: A Novel Alternate Receptor for CD154 during AlloimmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,188,152March 17, 2020June 30, 2029FORD, MANDY Lreporter.nih.gov
Clinical and genetic risk factors associated with adverse long-term health outcomes after curative therapies in individuals with sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,065,243March 15, 2021February 28, 2027DEBAUN, MICHAEL R.reporter.nih.gov
Diabetes Endothelial Keratoplasty Study(DEKS): Impact of Diabetes on Corneal Transplant Success and Cell LossNIHNational Eye Institute2021 to 2025$4,021,141May 1, 2021April 30, 2027LASS, JONATHAN Hreporter.nih.gov
Base editing and prime editing for sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,000,055January 1, 2021June 30, 2030WEISS, MITCHELL Jreporter.nih.gov
Combining Targeted RIT and Synergistic Novel Agent-RenewalNIHNational Cancer Institute2021 to 2025$3,984,924June 1, 2020May 31, 2027OROZCO, JOHNNIE JOSEreporter.nih.gov
Development of a Universal Assay for Minimal Residual Disease in Acute Myeloid Leukemia using Duplex SequencingNIHNational Cancer Institute2021 to 2025$3,984,664July 16, 2018January 31, 2027BICKEL, KELLIEreporter.nih.gov
Engineered Stem Cells for Cardiac RepairNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,984,462February 1, 2018March 31, 2027REGNIER, MICHAELreporter.nih.gov
A single antiviral to treat multiple opportunistic infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,962,651June 15, 2014March 31, 2026REMISZEWSKI, STACYreporter.nih.gov
Hematopoietic stem and progenitor cell regulation for enhanced clinical efficacyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,911,609August 1, 2015July 31, 2028KAPUR, REUBENreporter.nih.gov
Multi-center Evaluation of the Threat of Established and Emerging Respiratory Viral Infections in Pediatric Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,866,357September 17, 2021August 31, 2027STEINBACH, WILLIAM Jreporter.nih.gov
Gaining insight into psychiatric disease by engineering piece by piece the human brain in vitroNIHNational Institute of Mental Health2025$3,812,108August 1, 2015August 19, 2029PASCA, SERGIUreporter.nih.gov
BMT Survivor Study-2 (BMTSS-2)NIHNational Cancer Institute2021 to 2023$3,811,745April 1, 2019March 31, 2025BHATIA, SMITAreporter.nih.gov
Contact Pathway Inhibitor to Prevent Vascular Access FailureNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,810,461June 1, 2023March 31, 2027LORENTZ, CHRISTINA Ureporter.nih.gov
Novel therapeutic gene editing to induce fetal hemoglobin for sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,710,340September 1, 2023August 31, 2028WEISS, MITCHELL Jreporter.nih.gov
Harnessing the therapeutic potential of neural crest cells by manipulating the primary ciliumNIHNational Institute of Dental & Craniofacial Research2021 to 2024$3,694,614September 14, 2017June 30, 2025BRUGMANN, SAMANTHA Areporter.nih.gov
Optimizing Hematopoietic Stem Cell Transplantation For The Treatment Of Hematological MalignanciesNIHNational Cancer Institute2021 to 2025$3,687,540September 7, 2017June 30, 2032DIPERSIO, JOHN F.reporter.nih.gov
Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHDNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,648,726August 15, 2015May 31, 2026SARANTOPOULOS, STEFANIEreporter.nih.gov
Nourexal™: A Novel Bioenergetic Drug to Increase Donor Heart UtilizationNIHNational Heart, Lung, and Blood Institute2024 to 2025$3,632,845September 20, 2024June 30, 2026ELGEBALY, SALWA Areporter.nih.gov
HCMV-induced innate-like CD8 T cells and allogeneic HCT outcomeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,601,018April 9, 2021March 31, 2027HSU, KATHARINE Creporter.nih.gov
PERSISTENCE OF IMMUNE RESPONSES TO THE RECOMBINANT ZOSTER VACCINE IN IMMUNE COMPROMISED HOSTS WITH END-STAGE RENAL DISEASE WITH AND WITHOUT KIDNEY TRANSPLANTATIONNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,559,912March 6, 2019February 28, 2029WEINBERG, ADRIANAreporter.nih.gov
Preventing GVHD by inhibition of alloantigen presentation in the gutNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,543,040July 1, 2019June 30, 2027HILL, GEOFFREY ROGERreporter.nih.gov
Ocular Immune Regulation by Mesenchymal Stem CellsNIHNational Eye Institute2021 to 2025$3,542,949April 1, 2015September 14, 2028CHAUHAN, SUNIL Kreporter.nih.gov
Platform for Extended Kidney Preservation Via Subnormothermic PerfusionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$3,527,840September 20, 2024December 31, 2026KOPPARTHY, VARUN LINGAIAHreporter.nih.gov
Role of spleen educated monocytes in mediating ischemia-reperfusion injury followinglung transplant surgeryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,525,766April 1, 2019March 31, 2027BHARAT, ANKITreporter.nih.gov
1/2 Allogeneic Human Mesenchymal Stem Cell (MSC) Injection in Patients with Hypoplastic Left Heart Syndrome: A Phase IIb Clinical TrialNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,521,212September 15, 2020August 31, 2025BERGER, STUARTreporter.nih.gov
Intensive tailored exercise training with NAD+ precursor supplementation to improve muscle mass and fitness in adolescent and young adult survivors of hematopoietic stem cell transplantationNIHNational Cancer Institute2021 to 2025$3,469,202September 1, 2021August 31, 2027MOSTOUFI-MOAB, SOGOLreporter.nih.gov
Randomized trial of viral specific T-cell infusion to prevent viral infection after hematopoietic stem cell transplant.NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,457,708July 1, 2021April 30, 2027DAVIES, STELLA MARGARETreporter.nih.gov
Immunobiology of Lung Injury and FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,455,443January 21, 2019December 31, 2024MOORE, BETHANY B.reporter.nih.gov
Specification and Function of Tissue Resident and Recruited Macrophages in Cardiac Remodeling and Heart FailureNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,417,341January 15, 2022December 31, 2028LAVINE, KORY J.reporter.nih.gov
BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL ReconstructionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$3,403,884August 1, 2018July 31, 2025SPINDLER, KURT PAULreporter.nih.gov
Comparison of High Dose vs. Standard Dose Influenza Vaccines in Lung Allograft RecipientsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,375,497February 18, 2022January 31, 2027HALASA, NATASHA BASSAMreporter.nih.gov
Gene therapy for SCID-X1 with low dose busulfan and a SIN-lentiviral vectorNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,369,470July 7, 2016December 31, 2029WILLIAMS, DAVID Areporter.nih.gov
Mechanisms of Sensitization in High Risk Corneal GraftsNIHNational Eye Institute2021 to 2025$3,336,083August 1, 2000July 31, 2027DANA, REZAreporter.nih.gov
Hydrogels for human beta cell survival, function and evasion of immune rejectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,331,035September 15, 2022May 31, 2027GARCIA, ANDRES Jreporter.nih.gov
Enhancing Treg Therapeutic Efficacy in GVHDNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,322,892April 15, 2014March 31, 2027BLAZAR, BRUCE Rreporter.nih.gov
Graft extracellular vesicles as promoters of anti-donor immunity in cardiac and skin transplantationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,318,431September 19, 2022July 31, 2027MORELLI, ADRIAN E.reporter.nih.gov
Career Development in Pediatric and Medical OncologyNIHNational Cancer Institute2021 to 2025$3,314,336September 30, 1997August 31, 2026MESHINCHI, SOHEILreporter.nih.gov
Integrating a culturally competent APOL1 genetic testing program into living donor evaluationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,312,983April 1, 2021March 31, 2027AGRAWAL, AKANSHAreporter.nih.gov
Immunobiology of the normal and injured lungNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,312,758January 1, 2022December 31, 2028LOONEY, MARK ROBERTSreporter.nih.gov
Comprehensive Cardiac Structure-Function Analysis in Heart TransplantationNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,301,355February 4, 2014April 30, 2027MARKL, MICHAELreporter.nih.gov
Pathogenesis of lung injury mediated by lung-restricted antibodiesNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,293,690April 1, 2019March 31, 2027BHARAT, ANKITreporter.nih.gov
Comparison of High vs. Standard Dose Influenza Vaccines in Adult Solid Organ Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,293,620September 1, 2020June 30, 2025HALASA, NATASHA BASSAMreporter.nih.gov
Evolution of T cell immunity in blood and tissues over childhoodNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,243,813March 16, 2022February 28, 2027FARBER, DONNA L.reporter.nih.gov
Mechanisms of specification, quiescence, and regeneration of primordial germ cellsNIHNational Institute of General Medical Sciences2021 to 2025$3,240,052June 1, 2021September 30, 2026WESSEL, GARY Mreporter.nih.gov
Development of a Polymeric Percutaneous Pulmonary Valve for Use in Young ChildrenNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,231,750August 15, 2016February 28, 2029HARRINGTON, DANIEL Areporter.nih.gov
Targeting innate immunity for induction of robust renal allograft toleranceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,224,166July 25, 2023April 30, 2028KAWAI, TATSUOreporter.nih.gov
Protecting colonic mucus to mitigate acute intestinal graft-versus-host diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,218,917August 15, 2015June 30, 2026JENQ, ROBERTreporter.nih.gov
The Hemodynamic and Metabolic Effects of Advanced Circulatory Support for ResuscitationNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,211,098March 15, 2021February 28, 2026HALPERIN, HENRY Rreporter.nih.gov
Technology-Enabled Activation of Skin Cancer Screening for Hematopoietic Cell Transplantation Survivors and their Primary Care ProvidersNIHNational Cancer Institute2021 to 2024$3,192,137April 1, 2020March 31, 2026ARMENIAN, SAROreporter.nih.gov
Long-Term Islet Function and Impact after Total Pancreatectomy with Islet Autotransplant (LIFT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,185,530January 15, 2021December 31, 2026BELLIN, MELENA D.reporter.nih.gov
CRISPR-Modified Cardiac Xenograft TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,182,820June 10, 2020May 31, 2025PIERSON, RICHARD Nreporter.nih.gov
Developing preclinical xenograft models in zebrafish.NIHOffice of the Director, National Institutes of Health2022 to 2025$3,178,512March 1, 2022February 28, 2026LANGENAU, DAVID MICHAELreporter.nih.gov
Autologous BM-MSCs and Islet Co-transplantation to Enhance Islet Survival and Function in TP-IAT PatientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,169,762August 24, 2021May 31, 2027WANG, HONGJUNreporter.nih.gov
Hematopoietic Stem Cell And Cord Blood TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,169,146September 30, 2005May 31, 2030PETERSDORF, EFFIE Wreporter.nih.gov
Next Generation Therapies for Fertility Preservation in Male Cancer PatientsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$3,165,939May 15, 2020April 30, 2025ORWIG, KYLE EDWINreporter.nih.gov
Intrarenal B cells in acute kidney allograft rejectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,165,260February 15, 2020January 31, 2026CHONG, ANITA Sreporter.nih.gov
Ex Vivo Generation of Functional Kidney Tissues for TransplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$3,161,308September 1, 2020May 14, 2025LEWIS, JENNIFER A.reporter.nih.gov
Preclinical Assessment of a Compliance Matched Biopolymer Vascular GraftNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,139,611December 15, 2021November 30, 2026VANDE GEEST, JONATHAN PIETERreporter.nih.gov
Complement regulates macrophage and platelet function in kidney transplantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,127,980September 17, 2021August 31, 2026BALDWIN, WILLIAM Mreporter.nih.gov
Parametric Response Mapping (PRM) for the detection of chronic lung injury in hematopoietic cell transplant recipientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,121,383August 15, 2022July 31, 2026YANIK, GREGORY Areporter.nih.gov
Multi-ethnic high-throughput study to identify novel non-HLA genetic contributors to mortality after blood and marrow transplantationNIHNational Cancer Institute2021 to 2025$3,120,296August 1, 2021July 31, 2027HAHN, THERESA Ereporter.nih.gov
Gvl mHA Specific T Cell Responses Prevent AML Relapse Following Allogeneic Stem Cell Transplantation.NIHNational Cancer Institute2021 to 2025$3,119,515July 1, 2020June 30, 2027VINCENT, BENJAMIN Greporter.nih.gov
Targeted immune therapies in heart transplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,118,293February 1, 2023January 31, 2026ABDI, REZAreporter.nih.gov
Penetrating the “Black box”: Prediction of early Bronchiolitis obliterans in Pediatric Hematopoietic Stem Cell Transplant RecipientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,117,523July 15, 2021April 30, 2027MYERS, KASIANIreporter.nih.gov
Evaluation of the Mechanisms Underlying Induction and Maintenance Immunosuppression Impact on T Cell Function after Kidney TransplantationNIHNational Institute of Allergy and Infectious Diseases2025$3,106,301July 16, 2025June 30, 2029SCHAENMAN, JOANNA Mreporter.nih.gov
Engineering T cells to Promote Islet TransplantNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,102,316April 1, 2022March 31, 2027RILEY, JAMES L.reporter.nih.gov
Engineered Immune Cells for T1DNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,097,818April 1, 2022March 31, 2026MEYER, EVERETTreporter.nih.gov
Vascularized NICHE with local immunosuppression for cell replacement for Type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$3,096,729September 12, 2022May 31, 2027GRATTONI, ALESSANDROreporter.nih.gov
Epstein Barr Virus Driven Mechanisms of Post Transplant Lymphoproliferative DiseaseNIHNational Cancer Institute2023 to 2025$3,096,663September 1, 2023August 31, 2028MARTINEZ, OLIVIA Mreporter.nih.gov
MR-compatible Devices for the Diagnosis and Treatment of CardiomyopathiesNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,089,138August 20, 2021June 30, 2025KRAITCHMAN, DARA Lreporter.nih.gov
Privileged and primitive hematopoietic stem cells, niches, and regulatory T cellsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,081,005December 1, 2021November 30, 2025FUJISAKI, JOJIreporter.nih.gov
Anti-inflammatory Cell Based Repair of Intervertebral Disc DegenerationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,075,117September 1, 2021August 31, 2026CHAHINE, NADEEN O.reporter.nih.gov
BIOLOGICAL EMBEDDING OF CONTEXTUAL FACTORS IN HUMAN STEM CELLS: IMPLICATIONS FOR POPULATION HEALTH DIFFERENCESNIHNational Institute on Minority Health and Health Disparities2022 to 2025$3,074,250September 26, 2022June 30, 2027WADHWA, PATHIK Dreporter.nih.gov
Donor nonclassical monocytes mediate primary graft dysfunction and remote organ injury following lung transplant surgeryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,065,003January 1, 2019December 31, 2028BHARAT, ANKITreporter.nih.gov
NAVIGATE Kidney: A Multi-Level Intervention to Reduce Kidney Health DisparitiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$3,050,402September 1, 2023June 30, 2028CERVANTES, LILIAreporter.nih.gov
Beta-2 adrenergic signaling in immune homeostasis and reconstitutionNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,048,780April 15, 2022March 31, 2027CAO, XUEFANGreporter.nih.gov
Microengineering vascularized and innervated bone-like scaffolds as an alternative to autologous bone graftsNIHNational Institute of Dental & Craniofacial Research2021 to 2025$3,048,776August 1, 2021April 30, 2027BERTASSONI, LUIZ EDUARDOreporter.nih.gov
Dynamic OCE with acoustic micro-tapping for in vivo monitoring of skin graft surgeriesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,043,548April 1, 2021March 31, 2027PELIVANOV, IVANreporter.nih.gov
Acute Antibody Mediated Kidney Allograft RejectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,037,635September 17, 2021August 31, 2026FAIRCHILD, ROBERT Lreporter.nih.gov
Retinal Ganglion Cell Replacement in Clinically Relevant Models of Optic NeuropathyNIHNational Eye Institute2021 to 2022$3,026,491September 30, 2018August 31, 2024REX, TONIA Sreporter.nih.gov
The novel role of beta3 integrin in regulating alloimmunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,014,928February 14, 2022January 31, 2027ABDI, REZAreporter.nih.gov
Mechanisms of alloantibody production following renal transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,014,441February 22, 2021January 31, 2027VALUJSKIKH, ANNAreporter.nih.gov
Predicting the onset of chronic rejection in lung transplant recipients using hyperpolarized 129Xe imagingNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,009,446June 15, 2020May 31, 2026RIZI, RAHIM Rreporter.nih.gov
Commercialization Readiness for Bone Filler Scaffold Device to Aid in Dental Applications and ReconstructionNIHNational Institute of Dental & Craniofacial Research2021 to 2023$3,006,953September 22, 2018August 31, 2024BALLARD, SHARON Creporter.nih.gov
Generating Exogenic Organs for Transplantation without the Use of ImmunosuppressionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,005,890September 21, 2022July 31, 2027STEER, CLIFFORD JOHNreporter.nih.gov
Prolonged Normothermic Ex vivo Heart Perfusion (NEVHP)NIHNational Heart, Lung, and Blood Institute2022 to 2025$3,004,032September 1, 2022June 30, 2026ROJAS-PENA, ALVAROreporter.nih.gov
Personal tumor neoantigens for immunity against chronic lymphocytic leukemiaNIHNational Cancer Institute2022 to 2025$2,996,021June 1, 2011January 31, 2027WU, CATHERINE JU-YINGreporter.nih.gov
BiVACOR - A Physiological, Durable and Blood-Friendly Total Artificial HeartNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,992,071September 1, 2017April 30, 2024TIMMS, DANIELreporter.nih.gov
Systematic identification of minor histocompatibility antigens to address GVHDNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,991,041April 1, 2022March 31, 2026KESKIN, DERIN Breporter.nih.gov
i-AKC: Integrated AIRR Knowledge CommonsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,984,970August 1, 2023May 31, 2028COWELL, LINDSAY G.reporter.nih.gov
Stem Cell and Transplantation BiologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,984,057August 1, 2015July 31, 2028STIREWALT, DEREK Lreporter.nih.gov
Genetic, Environmental & Histologic Basis for Kidney Disease Risk among Persons Living with HIVNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,973,070September 1, 2018December 1, 2024LOCKE, JAYME ELIZABETHreporter.nih.gov
Integration and functionality of retinal organoid transplantsNIHNational Eye Institute2021 to 2025$2,971,351May 1, 2021March 31, 2027SEILER, MAGDALENE Jreporter.nih.gov
Photoabsorbing bioinks for expanding 3D printed human liver in situNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,967,973September 21, 2021May 31, 2026STEVENS, KELLY Rreporter.nih.gov
Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Cell Transplant RecipientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,966,978December 1, 2021November 30, 2026CHENG, GUANG-SHINGreporter.nih.gov
Optimizing Lung Transplant Benefit Using Agent-Based Simulation Modeling ApproachesNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,960,354June 1, 2020April 30, 2029VALAPOUR, MARYAMreporter.nih.gov
Defining the Landscape of HLA Risk Alleles in Primary Nephrotic Syndrome and Post Kidney Transplant RecurrenceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,958,614June 1, 2020May 31, 2026GBADEGESIN, RASHEED ADEBAYOreporter.nih.gov
MIDAS: MIcroangiopathy, endothelial Damage in Adults undergoing Stem cell transplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,957,506August 20, 2020July 31, 2026VASU, SUMITHIRAreporter.nih.gov
Kidney transplant Preemptive therapy or Prophylaxis (KPoP) for CMVPreventionin D+R- RecipientsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,952,999July 12, 2024May 31, 2031LIMAYE, ABHIJIT PRAKASHreporter.nih.gov
A critical role for macrophage ferroptosis in promoting fungal invasion in lung transplant recipientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,952,966April 1, 2021March 31, 2027HSU, JOE Lreporter.nih.gov
Preclinical studies of pluripotent stem cell-derived myogenic progenitors in non-human primatesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,948,443August 6, 2021December 31, 2026PERLINGEIRO, RITA C. R.reporter.nih.gov
Exosomes and the Immune Response in Allograft Outcomes in Pediatric Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,938,841May 10, 2022June 30, 2024KRAMS, SHERI M.reporter.nih.gov
T-cell depletion and maintenance of the HIV-1 latent reservoir in distinct tissue compartmentsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,927,774April 1, 2022March 31, 2027TOBIAN, AARON Areporter.nih.gov
In utero gene editing to cure a metabolic liver diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,918,864February 1, 2020January 31, 2026PERANTEAU, WILLIAM H.reporter.nih.gov
Retinal disease models for translational photoreceptor replacementNIHNational Eye Institute2021 to 2022$2,898,123September 30, 2018May 31, 2025WOLFE, JOHN Hreporter.nih.gov
High subzero preservation of liver for transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,898,028July 17, 2017December 31, 2025TONER, MEHMETreporter.nih.gov
Immunogenomic analysis of donor lung injury and its impact on clinical outcomes after lung transplantationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,897,255July 10, 2022June 30, 2027SHAVER, CIARA Mreporter.nih.gov
Circulating Proteomics to Phenotype the Development and Reversal of Myocardial Remodeling in Aortic StenosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,886,575April 1, 2023January 31, 2027LINDMAN, BRIAN RICHARDreporter.nih.gov
Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of FallotNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,871,936August 1, 2021July 31, 2027EGBE, ALEXANDERreporter.nih.gov
Using donor dendritic cells to optimize GvHD and GvL in allogeneic stem cell transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,867,908June 1, 2020May 31, 2026WALLER, EDMUND Kreporter.nih.gov
WNT1 Function in Stem Cells in Osteogenesis Imperfecta and Craniofacial-Skeletal TissuesNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,862,721September 10, 2021August 31, 2026LEE, BRENDANreporter.nih.gov
Elucidating the Molecular Mechanisms Underlying LYST-mediated Tissue Engineered Vascular Graft StenosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,861,908April 1, 2021March 31, 2026BREUER, CHRISTOPHER KANEreporter.nih.gov
Determinants of T Cell Fate in Transplantation ToleranceNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,859,856August 1, 2022July 31, 2027FORD, MANDY Lreporter.nih.gov
In Vivo Prevention of Murine GVHDNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,859,522July 1, 2022June 30, 2027BLAZAR, BRUCE Rreporter.nih.gov
Quantitative Multiparametric MRI to Assess the Effect of Stem Cell Therapy on Chronic Low Back PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,858,064August 1, 2014July 31, 2025LI, DEBIAOreporter.nih.gov
Molecular regulation of native hematopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,856,222February 15, 2016December 31, 2025CAMARGO, FERNANDOreporter.nih.gov
Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment Following Hematopoietic Stem Cell TransplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,855,157May 1, 2020April 30, 2026KELLER, MICHAEL DANIELreporter.nih.gov
Wnt signaling in hematopoietic developmentNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,849,578January 1, 2017June 30, 2025WILLERT, KARL Hreporter.nih.gov
Early-Stage Preclinical Validation of Carbon Monoxide Prodrugs for Acute Kidney InjuryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,842,625July 15, 2022June 30, 2027WANG, BINGHEreporter.nih.gov
Efficacy of a Mindfulness-Based Stress Management Program for Allogeneic HCT CaregiversNIHNational Cancer Institute2021 to 2025$2,839,105April 1, 2021March 31, 2027VINCI, CHRISTINEreporter.nih.gov
Development of platforms for beta cell-specific delivery and ligand discoveryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,837,648July 1, 2023June 30, 2027CHOUDHARY, AMITreporter.nih.gov
Developing gene therapy strategies to treat alpha thalassemiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,821,947January 1, 2022December 31, 2025MACKENZIE, TIPPIreporter.nih.gov
Genome editing of human pancreatic islets to withstand ischemic injuries and promote immune evasionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,817,305July 1, 2022April 30, 2027TANG, QIZHIreporter.nih.gov
Characterization of Renal Allograft Fibrosis and Prediction of Outcome Using a Quantitative MRI ApproachNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,812,749July 8, 2021April 30, 2027LEWIS, SARA Creporter.nih.gov
The role of the intestinal microbiome in cancer immunotherapyNIHNational Cancer Institute2023 to 2025$2,811,009August 1, 2023July 31, 2030VAN DEN BRINK, MARCEL R Mreporter.nih.gov
Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell TransplantationNIHNational Cancer Institute2022 to 2025$2,804,127July 22, 2022June 30, 2027VALDIMARSDOTTIR, HEIDDISreporter.nih.gov
Improving Medication Adherence in adolescents who had a Liver Transplant: iMALTNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,801,000September 20, 2018August 31, 2025SHEMESH, EYALreporter.nih.gov
Cognitive Function, Self-Management, and Health Outcomes among Liver Transplant Recipients: the LivCog CohortNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,788,955May 4, 2022February 28, 2027SERPER, MARINAreporter.nih.gov
Elastic, Degradable Vascular Grafts with Helical MicrofibersNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,787,042August 15, 2021July 31, 2025WANG, YADONGreporter.nih.gov
Accelerate cellular immunotherapy development for treatment of life-threatening childhood disordersNIHNational Center for Advancing Translational Sciences2021 to 2022$2,786,444August 1, 2018July 31, 2024PARK, JULIE Rreporter.nih.gov
Cardiovascular reserve capacity in survivors of hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,785,889February 1, 2020January 31, 2026ARMENIAN, SAROreporter.nih.gov
Reaching Equity in ACess to Home Dialysis And Re-Transplantation (REACH-DART)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,785,676May 15, 2022February 28, 2027KU, ELAINEreporter.nih.gov
Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,778,087July 1, 2022April 30, 2027GRATTONI, ALESSANDROreporter.nih.gov
Novel Biomarkers for Post-Liver Transplant NASH FibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,777,764July 18, 2022May 31, 2027ARTEEL, GAVIN Ereporter.nih.gov
Defining mechanisms of aortic root aneurysm in Loeys-Dietz syndrome using patients’ induced pluripotent stem cells and genome editingNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,760,413May 1, 2020April 30, 2026YANG, BOreporter.nih.gov
Base-Edited Hematopoietic Stem and Progenitor Cells To Enable Safe Use Of Highly Potent CD33-Targeted RadioimmunotherapyNIHNational Cancer Institute2022 to 2025$2,758,516July 1, 2022June 30, 2027WALTER, ROLAND BRUNOreporter.nih.gov
Functional Biointegration of Bioengineered Salivary Tissues in Irradiated Animal ModelsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,754,807September 19, 2022June 30, 2027FARACH-CARSON, MARY Creporter.nih.gov
Image-guided combination therapies for radiotherapy-induced neurocognitive impairment in pediatric brain tumor survivorsNIHNational Cancer Institute2021 to 2025$2,750,972July 12, 2021June 30, 2027NGEN, ETHEL JOSOreporter.nih.gov
Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant: The TEST TrialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,750,911May 19, 2022April 30, 2027SERPER, MARINAreporter.nih.gov
In vivo HSC gene therapy using a multi-modular HDAd vector for HIV cureNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,743,808January 10, 2023December 31, 2027LIEBER, ANDRE MICHAELreporter.nih.gov
Computational model-driven design to mitigate vein graft failure after coronary artery bypassNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,736,546August 15, 2022June 30, 2027MARSDEN, ALISON Lreporter.nih.gov
Conformal Total Body and Marrow Irradiation for LeukemiaNIHNational Cancer Institute2021 to 2024$2,727,228September 13, 2011December 31, 2025HUI, SUSANTA Kreporter.nih.gov
Role of TRPV4 channel signaling in lung ischemia-reperfusion injuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,714,601April 15, 2021March 31, 2026LAUBACH, VICTOR Ereporter.nih.gov
INSPIRE: INterventionS for Promoting kIdney tRansplant EmpowermentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,713,953September 1, 2023June 30, 2028CHAN, LILIreporter.nih.gov
Predictive modeling of acute rejection in pediatric heart transplant recipientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,708,586July 15, 2022June 30, 2027SOSLOW, JONATHAN HARVEYreporter.nih.gov
Ultrasonic Imaging of Bone Graft Healing in Extraction Sockets for Precise and Personalized Implant TherapyNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,707,757September 6, 2022August 31, 2026KRIPFGANS, OLIVER Dreporter.nih.gov
Metagenomic profiling of urinary cell-free DNA to monitor urinary tract infection after kidney transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,705,917March 10, 2020February 28, 2026DE VLAMINCK, IWIJNreporter.nih.gov
The role of HLA and its coreceptors in endothelial cell activation and leukocyte recruitment in antibody-mediated transplant rejectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,702,674September 1, 2018January 31, 2029REED, ELAINE Freporter.nih.gov
Epigenetic Profiling of circulating cell-free DNA for the Monitoring of Graft-Versus-Host Disease after Hematopoietic Cell TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,694,538January 13, 2020December 31, 2025DE VLAMINCK, IWIJNreporter.nih.gov
Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant RecipientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,690,675June 18, 2021April 30, 2027KENDRICK, JESSICA Breporter.nih.gov
Clinical Significance of MHC Haplotypes in HCTNIHNational Cancer Institute2021 to 2025$2,687,420March 1, 2003August 31, 2028PETERSDORF, EFFIE Wreporter.nih.gov
Enhancing Innate Immune Reconstitution Post Allogeneic HSCT.NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,685,463September 1, 2021June 30, 2025SERODY, JONATHAN S.reporter.nih.gov
Computational and Experimental Modeling of Subclinical Leaflet Thrombosis in Bioprosthetic Aortic ValvesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,685,262January 1, 2022December 31, 2026GRIFFITH, BOYCE EUGENEreporter.nih.gov
Implementation of an interventional, risk-adapted clinical trial for children with newly diagnosed juvenile myelomonocytic leukemia.NIHNational Cancer Institute2022 to 2025$2,677,641August 1, 2022July 31, 2027STIEGLITZ, ELLIOTreporter.nih.gov
Immuno-Isolating capsule for delivery of cell-based therapy for restoration of ovarian endocrine function in an animal modelNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,674,237August 15, 2022May 31, 2027SHIKANOV, ARIELLAreporter.nih.gov
Viral and host predictors of BK polyomavirus associated hemorrhagic cystitisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,671,817July 1, 2020June 30, 2026LASKIN, BENJAMIN LEWISreporter.nih.gov
Exploiting the VISTA Pathway to Prevent Acute GVHD and Control Steroid Refractory DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,663,582February 15, 2021January 31, 2026BLAZAR, BRUCE Rreporter.nih.gov
Peptide-dependent mobilization of CD8 regulatory cells in cardiac transplantationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,660,122August 21, 2023July 31, 2027AZZI, JAMILreporter.nih.gov
Post-transcriptional regulation of gene expression by microRNAs in antibody-mediated rejectionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,653,376September 1, 2022July 31, 2027IACOMINI, JOHN Jreporter.nih.gov
Airway epithelial cell and lymphocyte interactions in chronic lung allograft dysfunction pathogenesisNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,652,554August 15, 2022July 31, 2027GREENLAND, JOHNreporter.nih.gov
Improving Outcomes Assessment in Chronic Graft versus Host DiseaseNIHNational Cancer Institute2022 to 2025$2,646,165July 18, 2007March 31, 2027LEE, STEPHANIE Jreporter.nih.gov
Regulation of Skeletal progenitor cells in Osteogenesis ImperfectaNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,636,174July 13, 2022April 30, 2027PARK, DONGSUreporter.nih.gov
Stress and Human Stem/Progenitor Cells: Biobehavioral MechanismsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,635,227August 15, 2022June 30, 2027WADHWA, PATHIK Dreporter.nih.gov
Objective lung assessment tools for improved organ use in lung transplantationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,625,302July 15, 2021August 31, 2025CANTU, EDWARDreporter.nih.gov
Clinically Applicable Orofacial Cleft Reconstruction Using Structural, Compositional Biomimetic Bone ScaffoldsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,621,884August 1, 2022July 31, 2027LEE, SANG JINreporter.nih.gov
In Vivo Hematopoietic Stem Cell Gene Therapy of Beta-Thalassemia and Sickle Cell DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,618,613June 1, 2016July 31, 2025LIEBER, ANDRE MICHAELreporter.nih.gov
Impact of Randomized Payment Incentives on Disparities in Home Dialysis and Kidney TransplantationNIHNational Institute on Minority Health and Health Disparities2022 to 2025$2,608,764February 9, 2022November 30, 2026TRIVEDI, AMAL N.reporter.nih.gov
Development of 211Astatine-Conjugated Anti-CD45 Antibody-Based Conditioning for Hematopoietic Stem Cell Gene Therapy and EditingNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,608,434May 15, 2020April 30, 2026WALTER, ROLAND BRUNOreporter.nih.gov
Intravital analysis of hematopoietic stem cells in their bone marrow niche - Resubmission - 1NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,607,213September 20, 2021August 31, 2025REIZIS, BORISreporter.nih.gov
Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle lossNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,591,324March 1, 2021February 28, 2027SHIN, SU RYONreporter.nih.gov
An Interneuron-based Cell Therapy for EpilepsyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,589,602September 1, 2010March 31, 2027BARABAN, SCOTT Creporter.nih.gov
Development of a stem-cell derived thymic cell therapy to treat patients with athymiaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,586,728April 15, 2022January 31, 2027LIM, BINGreporter.nih.gov
Rectifying splicing mutations in blood disorders by gene editingNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,584,045December 20, 2019November 30, 2023BAUER, DANIEL EVANreporter.nih.gov
Microribbon scaffold-mediated Immunomodulation for Cranial Bone RepairNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,582,020January 1, 2015May 31, 2027YANG, FANreporter.nih.gov
Chronic Antibody-Mediated Rejection of Kidney AllograftsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,566,057February 1, 2022January 31, 2027FAIRCHILD, ROBERT Lreporter.nih.gov
The Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for OsteoarthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,563,053August 1, 2020July 31, 2025HUARD, JOHNNYreporter.nih.gov
Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile CommunicationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,560,634August 15, 2021July 31, 2025KAYLER, LIISEreporter.nih.gov
Modulated release of anti-senescence drugs to stimulate aged bone repairNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,553,994June 1, 2012January 31, 2027KUHN, LIISA TIINAreporter.nih.gov
Pathogenesis, prevention and treatment of corticosteroid-resistant gut GVHDNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,553,048February 15, 2023January 31, 2027ZENG, DEFUreporter.nih.gov
Vascular networks genetically engineered for protein drug deliveryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,552,882August 15, 2015April 30, 2026MELERO-MARTIN, JUAN Mreporter.nih.gov
Phase1/2a Clinical Trial of RPESC-derived RPE Transplantation as Therapy for Non-exudative Age-related Macular DegenerationNIHNational Eye Institute2021 to 2024$2,549,156September 30, 2020September 29, 2025STERN, JEFFREY Hreporter.nih.gov
Intestinal tissue intrinsic mechanisms in regulation of GI GVHDNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,544,373June 13, 2022May 31, 2027REDDY, PAVANreporter.nih.gov
Renal Anhydramnios Fetal Therapy (RAFT) TrialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$2,540,189April 1, 2020February 28, 2026ATKINSON, MEREDITH ANNreporter.nih.gov
Randomized study of low versus moderate dose busulfan in transplant for severe combined immunodeficiencyNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,529,105August 24, 2017July 31, 2024WAYNE, ALAN S.reporter.nih.gov
Modeling, pathogenesis and treatment of idiopathic pulmonary fibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,527,128September 20, 2016May 31, 2025SNOECK, HANS-WILLEM Ereporter.nih.gov
Promoting Increases in Living Organ Donation via Tele-navigation (PILOT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,523,913April 1, 2021February 28, 2026LOCKE, JAYME ELIZABETHreporter.nih.gov
Drug-gene-nutraceutical interactions of cannabidiolNIHNational Center for Complementary & Integrative Health2022 to 2025$2,519,234February 22, 2022January 31, 2027EADON, MICHAEL THOMASreporter.nih.gov
Automatic Wide-Field Optical Coherence Tomography for Assessment of Transplant Kidney ViabilityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,502,656September 15, 2022July 31, 2027ZHANG, XIAOHUI FRANKreporter.nih.gov
Using a SMART Design to Optimize PTSD Symptom Management Strategies Among Cancer SurvivorsNIHNational Cancer Institute2021 to 2024$2,482,100December 1, 2019November 30, 2025SMITH, SOPHIA K.reporter.nih.gov
Trimodal Vitality Imaging of Neural Progenitor Cells in the Spinal CordNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,476,665August 1, 2020April 30, 2027EMELIANOV, STANISLAV Yreporter.nih.gov
Organ banking for transplant--kidney cryopreservation by vitrification and novel nanowarming technologyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,474,268April 13, 2018March 31, 2027FINGER, ERIK BRIANreporter.nih.gov
Genetic-engineered control of the immunogeneic state of vascular composite allografts during preservationNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$2,471,566July 1, 2021March 31, 2029UYGUN, KORKUTreporter.nih.gov
Characterizing Emerging Humanized Immune Mouse Models for the study of transplant rejection and infectious disease pathology (Epstein Barr Virus)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,464,113February 2, 2021August 30, 2024BROWN, MATTHEW Ereporter.nih.gov
Mechanism of transplanted neonatal cardiac progenitor cells to repair ischemic myocardiumNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,462,741April 20, 2014August 31, 2025SCHUMACKER, PAUL Treporter.nih.gov
Identifying pathways required for integration of kidney organoid and host epitheliaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,461,009September 1, 2020May 31, 2025DRUMMOND, IAIN A.reporter.nih.gov
An integrated human stem cell model for elucidating myocardial-endocardial interactions in cardiac development and diseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,460,707February 15, 2021January 31, 2027ZHAO, MINGTAOreporter.nih.gov
Preservation of DCD Allograft Integrity for Liver TransplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,457,892January 13, 2020November 30, 2025BLACK, SYLVESTER Mreporter.nih.gov
Pathogenesis of Airway Stem Cell Abnormalities in Obliterative BronchiolitisNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,452,366April 1, 2019January 31, 2029PAREKH, KALPAJ RAJNIKANTreporter.nih.gov
Control of GVHD by Probiotics with individual Commensal BacteriaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,448,717May 5, 2022April 30, 2027YU, XUE-ZHONGreporter.nih.gov
A novel bioengineering approach to restoring permanent periodontal inflammatory bone lossNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,446,598July 1, 2023April 30, 2028JANG, HAE LINreporter.nih.gov
Improving Access to Nephrology Treatment and Care among Patients at Greatest Risk for Kidney FailureNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,442,134September 1, 2023June 30, 2028ARRIOLA, KIMBERLY RUTH JACOBreporter.nih.gov
Tomotherapy and Hematopoietic Stem Cells for Tolerance to Kidney TransplantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,439,463August 1, 2012April 30, 2024KAUFMAN, DIXON Breporter.nih.gov
Machine learning with immunogenetics for the prediction of hematopoietic cell transplant outcomesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,438,515January 5, 2021December 31, 2025HSU, KATHARINE Creporter.nih.gov
Post-Transplant Inflammatory ResponseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,437,884April 1, 1997November 30, 2029FAIRCHILD, ROBERT Lreporter.nih.gov
BMP2 Regulation of Periosteal FunctionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,436,018August 1, 2020April 30, 2026ROSEN, VICKIreporter.nih.gov
Stem cells for therapeutics discovery in genetic blood disordersNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,429,809September 23, 2016May 31, 2025DALEY, GEORGE Qreporter.nih.gov
Immunoregulatory Mechanisms of IL-33 in Heart TransplantationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,429,537August 10, 2022June 30, 2027TURNQUIST, HETH Rreporter.nih.gov
Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,428,878September 12, 2022May 31, 2026RAFII, SHAHINreporter.nih.gov
In vivo Monitoring of Neutrophil Function in Patients after Stem Cell TransplantNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,426,537February 13, 2023January 31, 2028IRIMIA, DANIELreporter.nih.gov
Allorecognition, parasitic stem cells and regeneration in a basal chordateNIHNational Institute of General Medical Sciences2021 to 2025$2,424,717January 1, 2021December 31, 2026DE TOMASO, ANTHONY Wreporter.nih.gov
High resolution transcriptome and gene regulatory mapping of human ureter and bladder across the lifespanNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,415,000September 30, 2021July 31, 2027WESSELY, OLIVERreporter.nih.gov
Mathematical ecology models of host-microbiota interaction in auto microbiota transplants (auto-FMT)NIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,414,163February 1, 2019January 31, 2024XAVIER, JOAOreporter.nih.gov
New approaches to kidney banking through nature-inspired high sub-zero preservation strategiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,410,750August 5, 2019August 31, 2026WEEGMAN, BRADLEY Preporter.nih.gov
Control of dysfunctional TregsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,407,966February 1, 2014January 31, 2027LI, XIAN CHANGreporter.nih.gov
SMART BIOELECTRONIC IMPLANTS FOR CONTROLLED DELIVERY OF THERAPEUTIC PROTEINS IN VIVO AND ITS APPLICATION IN LONG-TERM TREATMENT OF HEMOPHILIA ANIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,406,599May 1, 2022January 31, 2026ANDERSON, DANIEL Greporter.nih.gov
Designing induction therapies to target memory T cells in high risk recipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,405,990July 15, 2014August 31, 2027VALUJSKIKH, ANNAreporter.nih.gov
The immunogenicity and pathogenicity of HLA-DQ in solid organ transplantationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,399,982August 17, 2023July 31, 2027TAMBUR, ANAT R.reporter.nih.gov
Continuation of The Collaborative Islet Transplantation Registry (CITR)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,399,074September 15, 2022June 30, 2027PAYNE, ELIZABETH HOLLYreporter.nih.gov
Targeting heat shock protein 72 to improve renal function after transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,394,886March 15, 2021July 31, 2026PARAJULI, NIRMALAreporter.nih.gov
Optimizing Surgical Transplant of CFTR Gene-Corrected Human Basal Stem Cells to the Upper AirwayNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,392,495March 1, 2021January 31, 2027NAYAK, JAYAKAR Vreporter.nih.gov
Promoting T cell reconstitution after hematopoietic cell transplantationNIHNational Heart, Lung, and Blood Institute2024 to 2025$2,391,092January 1, 2024December 31, 2030DUDAKOV, JARRODreporter.nih.gov
Scalable and transplantable pancreatic islet organoids with engineered oxygenationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$2,390,830September 1, 2025August 31, 2029KOMATSU, HIROTAKEreporter.nih.gov
HIV Reservoir and Gene Modified Cell Dynamics Following Autologous Stem Cell TransplantationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,390,244January 13, 2023December 31, 2026HENRICH, TIMOTHY JENSENreporter.nih.gov
Epithelial stem/progenitor cells as repair agents in diffuse alveolar damageNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,388,592September 21, 2016May 31, 2025CHAPMAN, HAROLD Areporter.nih.gov
Development of heparan sulfate-based therapeutics to treat inflammatory diseasesNIHNational Institute of General Medical Sciences2023 to 2025$2,387,583September 14, 2021July 31, 2026WANG, ZHANGJIEreporter.nih.gov
Virtually Supervised Exercise for Kidney Transplant CandidatesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,386,134September 15, 2022August 31, 2027LIU, CHRISTINE KEEreporter.nih.gov
Regulation of Ribosome Biogenesis in Hematopoietic Stem CellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,385,337September 18, 2020August 31, 2025TONG, WEIreporter.nih.gov
Access to Kidney Transplantation in Minority Populations (AKT-MP)NIHNational Institute on Minority Health and Health Disparities2021 to 2025$2,384,015July 7, 2020January 31, 2026MYASKOVSKY, LARISSAreporter.nih.gov
Small molecule therapeutic for calcific aortic valve diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,378,349August 1, 2023May 31, 2027SRIVASTAVA, DEEPAKreporter.nih.gov
Overcoming humoral rejection after xenotransplantation in sensitized nonhuman primate recipientsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,378,023February 6, 2023January 31, 2028KWUN, JEANreporter.nih.gov
Trillion cell culture to fuel organ biofabricationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,361,000September 1, 2022August 31, 2027SKYLAR-SCOTT, MARK A.reporter.nih.gov
CGT and ACD Inhibitors for SRT Treatment of Krabbe DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,357,715September 22, 2022August 31, 2027BONGARZONE, ERNESTO ROQUEreporter.nih.gov
In Vivo Detection And Mechanisms of Regulatory B cell Function in TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,357,214July 1, 2015March 31, 2027ROTHSTEIN, DAVID Mreporter.nih.gov
Immunosuppression-free transplantation through placental mimicryNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,355,000September 14, 2021August 31, 2026WEAVER, JESSICA DIANEreporter.nih.gov
Multipotent ABCB5-positive cell therapeutics for corneal diseaseNIHNational Eye Institute2021 to 2022$2,352,662April 1, 2018January 31, 2024FRANK, NATASHA Yreporter.nih.gov
3D Bioprinted Spinal Cord Organoids as a Relay System for Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,352,214September 2, 2021June 30, 2026PARR, ANN Mreporter.nih.gov
Developing a platform for human somatic cell rejuvenation, expansion and genetic engineering using synthetic RNA moleculesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,346,523May 1, 2021April 30, 2027KOGUT, IGORreporter.nih.gov
Outcomes in living kidney donors over 50 years compared to a healthy matched contemporaneous non-donor cohort from the same geographical regionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,341,803July 1, 2020April 30, 2025MATAS, ARTHUR Jreporter.nih.gov
Retinal sheet transplant impact on functional organization of visual cortex in retinal degenerate animal modelsNIHNational Eye Institute2022 to 2025$2,340,862May 1, 2022March 31, 2027LYON, DAVID Creporter.nih.gov
HLA Immunogenetics and kidney allograft outcomesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,338,883November 21, 2022October 31, 2027KAMOUN, MALEKreporter.nih.gov
Molecular basis and protective efficacy of cross-neutralizing antibodies against four major respiratory virusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,338,206March 16, 2023February 29, 2028BOONYARATANAKORNKIT, JIMreporter.nih.gov
Computer-Assisted Histologic Evaluation of Cardiac Allograft RejectionNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,335,528September 1, 2020August 31, 2025MARGULIES, KENNETH BERreporter.nih.gov
The Synthetic Kidney: A Revolutionary Solution for the Shortage of Kidneys for TransplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,335,138September 15, 2022August 31, 2027LI, ZHONGWEIreporter.nih.gov
Lymph Node Delivery in TransplantationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,334,750June 18, 2022May 31, 2027ABDI, REZAreporter.nih.gov
Chemotherapy-free cure of hemoglobin disorders through base editingNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,334,252September 1, 2023May 31, 2027BAUER, DANIEL EVANreporter.nih.gov
Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,333,316September 15, 2016May 31, 2025ZHANG, JIANYIreporter.nih.gov
Impact of Treating Asymptomatic CMV Replication on Cardiovascular Risk in Treated HIV InfectionNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,331,970August 20, 2020July 31, 2025HUNT, PETER Wreporter.nih.gov
Role of Brain Macrophages in the Pathogenesis and Treatment of Globoid Cell LeukodystrophyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,327,864May 3, 2021March 31, 2027BENNETT, FREDERICKreporter.nih.gov
Mechanisms whereby IFN-gamma sensitizes AML to the graft-vs-leukemia effectNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,325,780April 20, 2021March 31, 2026SHLOMCHIK, WARREN Dreporter.nih.gov
ABCB5-positive stem cells for LSCD therapyNIHNational Eye Institute2023 to 2025$2,325,074June 1, 2016May 31, 2028FRANK, MARKUS H.reporter.nih.gov
Novel roles for p27 as transcriptional co-regulator of cJun in stem cells and developmentNIHNational Cancer Institute2021 to 2024$2,319,039September 1, 2020August 31, 2025SLINGERLAND, JOYCE MARIEreporter.nih.gov
Novel Intervention Approaches to Alleviate Allogeneic Transplant-Related Morbidity and MortalityNIHNational Cancer Institute2021 to 2024$2,315,110September 3, 2018January 31, 2026SORROR, MOHAMEDreporter.nih.gov
Derivation of pancreatic islet-like organoids from human gastric stem cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,313,256August 24, 2022May 31, 2026RAFII, SHAHINreporter.nih.gov
Biologic correlatives of chronic GVHD onsetNIHNational Cancer Institute2021 to 2023$2,309,532July 2, 2019June 30, 2025LEE, STEPHANIE Jreporter.nih.gov
The Impact of Structural Racism on Racial/Ethnic Disparities in End-Stage Kidney Disease from Healthy Population to MortalityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$2,304,849August 1, 2022April 29, 2025DAW, JONATHAN KYLEreporter.nih.gov
IL-33 induced-lL-9 producing type 2 innate lymphoid cells in the regulation of acute lung injury after hematopoietic stem cell transplantation (HSCT) in pediatric patientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,303,969January 1, 2022June 30, 2026PACZESNY, SOPHIEreporter.nih.gov
Transplantation of MHC Homozygous Vascular Progenitors in PrimatesNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,302,970September 20, 2016May 31, 2025SLUKVIN, IGOR I.reporter.nih.gov
The impact of upper gastrointestinal dysmotility on aspiration-associated aerodigestive disorders in childrenNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,300,603July 1, 2015May 31, 2027ROSEN, RACHEL Lreporter.nih.gov
T cell invasion of the stem cell compartment during immune-mediated GI damageNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,299,846January 1, 2021December 31, 2025HANASH, ALAN Mreporter.nih.gov
Engineering optimization and scaling enables high quality pancreatic islet cryopreservation for banking and transplantNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,294,596September 22, 2021July 31, 2025FINGER, ERIK BRIANreporter.nih.gov
Multi-omic Biomarker Discovery and Validation in Heart Transplant Patient PopulationsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,294,125March 1, 2020June 30, 2023KEATING, BRENDAN JAMESreporter.nih.gov
Treatment-Related Cardiotoxicity in Children with Relapsed Acute Myeloid Leukemia - Natural History, Occurrence and ImplicationsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,291,761July 15, 2022June 30, 2027GETZ, KELLY DIRINGERreporter.nih.gov
Understanding and targeting bone marrow microenvironment in myelofibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,288,703January 1, 2021December 31, 2025DING, LEIreporter.nih.gov
HuR/HIF – SIRT1 Signaling Axis in Liver Transplant RejuvenationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,287,369April 1, 2003March 31, 2027KUPIEC-WEGLINSKI, JERZY Wreporter.nih.gov
Biomechanical Determinants of Hematopoietic Stem Cell PotentialNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,282,783January 15, 2018November 30, 2026WENZEL, PAMELA LYNNreporter.nih.gov
The Role of Donor-Derived Eosinophils on Lung Allograft Ischemia Reperfusion InjuryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,276,035February 1, 2019August 31, 2030KRUPNICK, ALEXANDER S.reporter.nih.gov
IRI, innate immunity and transplant rejectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,266,791March 15, 2021February 28, 2026ABDI, REZAreporter.nih.gov
Tapeworm stem cells as drivers of regeneration and reproductionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,265,000March 5, 2021February 28, 2027ROZARIO, TANIAreporter.nih.gov
Liver Xenotransplantation using CRISPR-modified Porcine OrgansNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,264,625February 1, 2020December 1, 2023MARKMANN, JAMES FRANCISreporter.nih.gov
High resolution lineage tracing of developmental hematopoiesisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,256,385May 5, 2023February 28, 2027CAMARGO, FERNANDOreporter.nih.gov
Preparation for lung transplant discussions and decisions among people with cystic fibrosisNIHNational Institute of Nursing Research2023 to 2025$2,255,861April 19, 2023January 31, 2028RAMOS, KATHLEEN JESSICAreporter.nih.gov
Genetic Testing (APOL1) Decisional Support for Potential Living Kidney DonorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,255,854September 30, 2021April 30, 2026GARDINER, HEATHER MARIEreporter.nih.gov
A stem cell activated cryogel bioscaffold that restores islet bioenergetics while providing oxygen and nutrients at extravascular sites of transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,251,861April 1, 2022March 31, 2027THAKOR, AVNESH SINHreporter.nih.gov
Elution of a Small Molecule from a Bio Ceramic Collagen Bone Graft Device Heals Bone while InhibitingBreast Cancer Bone MetastasesNIHNational Cancer Institute2021 to 2022$2,249,777November 30, 2021August 31, 2022MARGULIES, BRYAN SAMUELreporter.nih.gov
The impact of body composition on peri-operative and patient-centered outcomes in lung transplantation.NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,249,248August 5, 2022July 31, 2027SINGER, JONATHAN PAULreporter.nih.gov
Culture-free pathogen tracking in hospitalized patientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,245,086April 3, 2020March 31, 2025BHATT, AMI SIDDHARTHreporter.nih.gov
Defining Protective CMV Immunity after TransplantationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,244,070February 6, 2023January 31, 2028HILL, GEOFFREY ROGERreporter.nih.gov
Blockade of IL-23 for the Prevention of Graft Versus Host DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,237,924April 15, 2021March 31, 2026DROBYSKI, WILLIAM R.reporter.nih.gov
Intraoperative bioprinting of composite tissues with zonal stratification for craniomaxillofacial reconstructionNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,227,502January 1, 2020December 31, 2025OZBOLAT, IBRAHIMreporter.nih.gov
Inflammatory Cytokine Networks in Gastrointestinal Tract Graft Versus Host DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,224,558August 1, 2015November 30, 2027DROBYSKI, WILLIAM R.reporter.nih.gov
Viral and immune kinetics in rhinovirus infection following hematopoietic cell transplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,222,417June 4, 2020May 31, 2025WAGHMARE, ALPANA AMALKANTreporter.nih.gov
Tissue resident memory T cells and chronic lung allograft dysfunctionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,220,732July 20, 2023April 30, 2028SNYDER, MARK EUGENEreporter.nih.gov
Multiplex base/prime editors for in vivo selection of modified HSPCs in hemoglobinopathyNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,218,334January 17, 2017December 31, 2025KIEM, HANS-PETERreporter.nih.gov
Intra-graft C1 esterase inhibitor therapy for deceased kidney transplantationNIHNational Institute of Allergy and Infectious Diseases2024$2,216,525September 1, 2024August 31, 2031HEEGER, PETER SCOTTreporter.nih.gov
Intra-graft C1 esterase inhibitor therapy for deceased kidney transplantationNIHNational Institute of Allergy and Infectious Diseases2025$2,216,525September 1, 2024August 31, 2031HEEGER, PETER SCOTTreporter.nih.gov
Protein biomarkers to predict pain outcomes after total pancreatectomy with islet autotransplantNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,216,262September 22, 2023July 31, 2027BELLIN, MELENA D.reporter.nih.gov
Investigating the role of frailty on outcomes in acutely ill patients with cirrhosis undergoing liver transplantation in the acute care settingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,213,082July 15, 2023April 30, 2028LAI, JENNIFER C.reporter.nih.gov
Lung transplant injury drives chronic lung allograft dysfunction via recruitment ofmonocyte-derived alveolar macrophagesNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,211,115September 1, 2020August 31, 2024MISHARIN, ALEXANDERreporter.nih.gov
Enhancing endothelial cell engraftment via transplantation of exogenous mitochondriaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,206,197December 20, 2020November 30, 2024MELERO-MARTIN, JUAN Mreporter.nih.gov
Ex-vivo bioengineered technology to unravel dysfunction due to non-alcoholic steatohepatitis (NASH)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,201,102July 1, 2023April 30, 2027WERTHEIM, JASON Areporter.nih.gov
Strategies to Enhance Engineered Heart Tissue Based Myocardial RepairNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,196,794January 1, 2023November 30, 2026ZHU, WUQIANGreporter.nih.gov
Rewiring the Injured Brain with GABA ProgenitorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,163,757February 15, 2016March 31, 2027HUNT, ROBERT Freporter.nih.gov
Using human skin grafted mice to identify biomarkers of exposure and study effects of radiation on skinNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,157,978February 21, 2020January 31, 2025CLARK, RACHAEL ANNreporter.nih.gov
Complement-Mediated Exosome Function in TransplantationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,152,526September 22, 2022July 31, 2027CHUN, NICHOLASreporter.nih.gov
Innate Allorecognition in Clinical Organ TransplantationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,152,469December 20, 2022June 30, 2025LAKKIS, FADI G.reporter.nih.gov
Mechanisms of accelerated calcification and structural degeneration of implantable biomaterials in pediatric cardiac surgeryNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,151,713April 1, 2023January 31, 2027FERRARI, GIOVANNIreporter.nih.gov
Clinical and mechanistic studies defining optimal preparative approaches to infants with IL2RG/JAK3/RAG1/RAG2 SCID: a randomized trial of busulfan dosageNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,149,845August 13, 2024May 31, 2029AULETTA, JEFFERY Jreporter.nih.gov
Long Term Oral Health Outcomes in the Chronic GVHD ConsortiumNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,148,169August 1, 2019July 31, 2025TREISTER, NATHANIEL Sreporter.nih.gov
Discriminating EGFR function in T cells and epithelium during immune-mediated tissue damageNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,147,877August 25, 2018June 30, 2028HANASH, ALAN Mreporter.nih.gov
Immunogenicity of Human Stem Cell-Derived Beta Cells and Muscle Cells in Humanized MiceNIHOffice of the Director, National Institutes of Health2021 to 2022$2,147,498August 15, 2019July 31, 2024GREINER, DALE LESLIEreporter.nih.gov
Targeting the transcriptional co-activators YAP and TAZ with statins to prevent solid organ transplant rejection by HLA donor specific antibodiesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,144,831July 19, 2023June 30, 2028REED, ELAINE Freporter.nih.gov
Vascular Regeneration with Direct Reprogramming and Engineering StrategiesNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,143,183August 1, 2022July 31, 2026YOON, YOUNG-SUPreporter.nih.gov
Non-APOL1 genetic factors and kidney transplant outcomesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,142,442August 15, 2023May 31, 2028KIRYLUK, KRZYSZTOFreporter.nih.gov
Readily Available Stem Cell-Based Vascular Grafts for Emergent Surgical CareNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,141,117July 1, 2020June 30, 2025QYANG, YIBINGreporter.nih.gov
Integrated analysis of HCC CTCs for Liver Transplant Candidate SelectionNIHNational Cancer Institute2021 to 2024$2,139,039April 1, 2020March 31, 2026AGOPIAN, VATCHEreporter.nih.gov
Cell adhesion and tissue dynamics in the skinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$2,136,170December 1, 1980August 31, 2028FUCHS, ELAINEreporter.nih.gov
Machine Learning to identify Biomarkers for Risk of Chronic Graft-Versus-Host DiseaseNIHNational Cancer Institute2022 to 2025$2,133,819December 2, 2021November 30, 2026PACZESNY, SOPHIEreporter.nih.gov
The Role of Telomeres in Lung Transplant Recipient Immunity and OutcomesNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,129,020March 5, 2023February 29, 2028MCDYER, JOHN Freporter.nih.gov
Endothelial cell specification at the osteogenic and angiogenic interface in cranial bone tissue engineeringNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,124,583September 3, 2020May 31, 2027ZHANG, XINPINGreporter.nih.gov
Mechanisms controlling epicardial-dependent promotion of heart regeneration in zebrafish.NIHNational Heart, Lung, and Blood Institute2021 to 2025$2,118,750July 5, 2021June 30, 2027CAO, JINGLIreporter.nih.gov
Curation of genetic defects causing combined immunodeficiency and infections in childrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$2,115,359July 1, 2021June 30, 2028CHINN, IVAN KINGYUEreporter.nih.gov
Development of a Fully-Implantable Ventricular Assist Device for Neonates and Children with Heart Failure - with Magnetic Levitation to Improve HemocompatibilityNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,115,146August 1, 2020June 30, 2025FRAZIER, O. H.reporter.nih.gov
Investigating hematopoietic stem cell dysfunction during sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,111,564April 1, 2023March 31, 2027MCKINNEY-FREEMAN, SHANNON Lreporter.nih.gov
Engineering synthetic cellular crosstalk for transplantation toleranceNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,109,666February 1, 2022January 31, 2027MA, LEYUANreporter.nih.gov
Non-Invasive Venous waveform Analysis (NIVA) for Monitoring Volume Status in Heart Failure PatientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,103,997August 1, 2019June 30, 2029ALVIS, BRET D.reporter.nih.gov
Role of Eosinophils in Hepatic Ischemia Reperfusion InjuryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,103,519June 1, 2019March 31, 2027JU, CYNTHIAreporter.nih.gov
A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation with Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients with Severe Aplastic AnemiaNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,102,265April 1, 2022March 31, 2029WILLIAMS, DAVID Areporter.nih.gov
Mechanistic Inflammatory Pathways in Graft Versus Host DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,100,486August 1, 2020May 31, 2026DROBYSKI, WILLIAM R.reporter.nih.gov
High subzero heart preservation: from zebrafish to mammalsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,100,000April 1, 2021March 31, 2027TESSIER, SHANNON NOELLAreporter.nih.gov
Skeletal Muscle Regeneration from Pluripotent Stem CellsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,097,940June 1, 2021May 31, 2027PERLINGEIRO, RITA C. R.reporter.nih.gov
Immuno and Epigenetics of Hematopoietic Cell TransplantationNIHNational Cancer Institute2021 to 2025$2,093,460August 1, 2017April 30, 2028PETERSDORF, EFFIE Wreporter.nih.gov
Local immune modulation for beta cell replacement therapy in type 1 diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,091,787April 1, 2022December 31, 2026PHELPS, EDWARDreporter.nih.gov
Reaching Equity for Adults and CHildren in Transplant (REACH-TRANSPLANT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,085,721September 11, 2019June 30, 2025KU, ELAINEreporter.nih.gov
Vitamin D Deficiency, Insulin Resistance and Cardiovascular diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,078,647April 15, 2010March 31, 2027BERNAL-MIZRACHI, CARLOSreporter.nih.gov
Lacrimal Gland Repair Using Progenitor CellsNIHNational Eye Institute2021 to 2025$2,077,504January 1, 2016June 30, 2027MAKARENKOVA, HELEN P.reporter.nih.gov
A place-based approach to geographic disparities in lung transplantNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,075,369August 1, 2023May 31, 2028TSUANG, WAYNE Mreporter.nih.gov
PET Tracer for Imaging of Lung InflammationNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,072,841September 1, 2023May 31, 2027SHARMA, VIJAYreporter.nih.gov
Reduction of bloodstream infections from oral organisms in pediatric stem cell transplant: a randomized multicenter double-blind placebo-controlled study evaluating twice daily oral xylitolNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,064,644September 1, 2022August 31, 2027DANDOY, CHRISTOPHER EUGENEreporter.nih.gov
Human iPSC-Based Personalized Cell Therapy of PDNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,062,628July 1, 2023April 30, 2028KIM, KWANG-SOOreporter.nih.gov
Dissecting the role of dynamic epigenome prompting pathways leading to kidney allograft fibrosisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$2,062,322July 1, 2019June 30, 2025MAS, VALERIA RAQUELreporter.nih.gov
Deciphering unintended large gene modifications in gene editing for sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,057,558July 1, 2023June 30, 2027BAO, GANGreporter.nih.gov
BIOMATERIALS FOR STEM CELL-DERIVED BETA CELL TRANSPLANTATIONNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$2,054,178September 17, 2021July 31, 2026GARCIA, ANDRES Jreporter.nih.gov
Novel Kidney Injury Tools in Deceased Organ Donation to Predict Graft OutcomesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,054,144August 15, 2012November 30, 2026PARIKH, CHIRAG Rreporter.nih.gov
Early detection of pulmonary complications of hematopoietic stem-cell transplantation in children using hyperpolarized xenon MRINIHNational Heart, Lung, and Blood Institute2023 to 2025$2,049,864February 15, 2023December 31, 2027WALKUP, LAURA LEEreporter.nih.gov
Long-acting injectable tacrolimus for chronic immunosuppressionNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$2,047,614July 8, 2022June 30, 2025SMITH, THOMAS J.reporter.nih.gov
The Biological Consequences of Age-related Clonal HematopoiesisNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,046,875February 10, 2021January 31, 2027GONDEK, LUKASZ PAWELreporter.nih.gov
Targeting epigenetic regulation via Bromodomain and Extraterminal (BET) domain inhibition for treatment of GVHDNIHNational Cancer Institute2021 to 2025$2,045,952April 5, 2021March 31, 2027CHOE, HANNAHreporter.nih.gov
Bioengineering Cornea with Autologous Stem CellsNIHNational Eye Institute2022 to 2025$2,045,272May 1, 2016March 31, 2027FEINBERG, ADAM WALTERreporter.nih.gov
Targeted conditioning to maximize prenatal HSC engraftment for SCDNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,044,659July 1, 2023June 30, 2027ALMEIDA-PORADA, GRACA DUARTEreporter.nih.gov
Neuropilin-2 in AlloimmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,036,192March 1, 2020February 28, 2026BRISCOE, DAVID M.reporter.nih.gov
Embryonic vascular stem-progenitors for treatment of ischemic retinopathiesNIHNational Eye Institute2021 to 2024$2,033,849February 1, 2021January 31, 2026ZAMBIDIS, ELIAS T.reporter.nih.gov
A first in class, mechanism-guided, cell-based therapy for complex regional pain syndromeNIHNational Institute of Neurological Disorders and Stroke2022$2,033,135September 24, 2022August 31, 2025CHENG, JIANGUOreporter.nih.gov
Chronic Versus Acute Transplantation of Neural Tissues for TBI-Induced Cortical InjuriesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,031,527July 1, 2021June 30, 2027CHEN, HAN-CHIAO ISAACreporter.nih.gov
Notch Signaling in AlloimmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,031,145April 22, 2011May 31, 2027PEAR, WARREN Sreporter.nih.gov
Senescent cells drive mt-DNA accumulation and inflamm-agingNIHNational Institute on Aging2021 to 2024$2,028,164June 15, 2020April 30, 2026TULLIUS, STEFAN GUNTHERreporter.nih.gov
Fecal Microbiota Transplant for C. difficile Infection in Solid Organ Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$2,027,511September 15, 2018August 31, 2023SAFDAR, NASIAreporter.nih.gov
Optimizing HCT Outcomes: A Multi-omic InvestigationNIHNational Heart, Lung, and Blood Institute2025$2,024,340August 15, 2025May 31, 2030KEAN, LESLIE Sreporter.nih.gov
The role of GSK3/PPAR-/mitophagy pathway in regulating hematopoiaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,023,914January 1, 2022December 31, 2025HUANG, JIANreporter.nih.gov
Synthetic Mesenchymal Stem Cell Niches for Vascular TherapyNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,023,009August 15, 2013July 31, 2025TAN, WEIreporter.nih.gov
Continuous allocation score design for guaranteeing equity and reducing discards in kidney and liver transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,022,974December 17, 2022November 30, 2027MASSIE, ALLAN Breporter.nih.gov
Length-dependent activation in human myocardiumNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,020,753September 15, 2020July 31, 2025CAMPBELL, KENNETH Sreporter.nih.gov
Mechanisms and Ex Vivo Repair of Cold-Storage Injury in Human Kidney AllograftsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,018,635February 28, 2020January 31, 2026POBER, JORDAN Sreporter.nih.gov
Corneal Scar Repair through SPAACKL: Sutureless, Pro-regenerative Anterior Additive Collagen gel KeratopLastyNIHNational Eye Institute2022 to 2025$2,017,989March 1, 2022December 31, 2026MYUNG, DAVIDreporter.nih.gov
Exosome educated monocytes for acute radiation syndromeNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,007,828August 1, 2021July 31, 2025CAPITINI, CHRISTIANreporter.nih.gov
Multiplexed rapid immunoassay for invasive fungal diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$2,004,963September 23, 2020August 31, 2025KOZEL, THOMAS Rreporter.nih.gov
The novel role of HLA-E restricted CD8 regulatory T cells in kidney allograft rejectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,004,858July 12, 2023June 30, 2028AZZI, JAMILreporter.nih.gov
PHMB-Impregnated Acellular Biologic Grafts for Treatment of Third-Degree BurnsNIHNational Institute of General Medical Sciences2023 to 2024$2,004,706January 18, 2021August 31, 2025BLUM, JULIANA LYNreporter.nih.gov
A Bullet Proof vascular graft to prevent dialysis access cannulation injuryNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,999,167September 1, 2016June 30, 2023KNIGHT, JOSEPHreporter.nih.gov
Cell adhesion-dependent mechanisms of beta cell growth and homeostasisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,998,151April 1, 2020February 28, 2025CIRULLI, VINCENZINOreporter.nih.gov
HCMV Therapeutic Antibody Safety TrialNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,996,288July 1, 2020June 30, 2025KAUVAR, LAWRENCE MICHAELreporter.nih.gov
Development of a Novel Bone Adhesive Scaffold to Accelerate Bone Regeneration and Improve Ridge Height Maintenance for the Treatment of Patients with Residual Ridge ResorptionNIHNational Institute of Dental & Craniofacial Research2023 to 2024$1,995,660June 1, 2023May 31, 2025JADIA, RAHULreporter.nih.gov
Phase 2 clinical trial of a novel T cell therapy following bridging therapy with hypomethylating agents for relapsed AML patients post-stem cell transplantNIHNational Cancer Institute2023 to 2025$1,994,514August 10, 2023July 31, 2026VERA, JUAN FERNANDOreporter.nih.gov
Extended preservation of human livers: a nature inspired, high subzero controlled, limited freezing approachNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$1,992,855September 13, 2019August 31, 2025BAICU, SIMONA Creporter.nih.gov
Engineering an immuno-isolating hydrogel for restoring ovarian endocrine functionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,991,992September 30, 2016February 28, 2026SHIKANOV, ARIELLAreporter.nih.gov
Neonatal and Young Pediatric Kidney Preservation through Nanowarming and VitrificationNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,991,119September 14, 2018June 30, 2027WEEGMAN, BRADLEY Preporter.nih.gov
Automated System for High Yield Pancreatic Islet IsolationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,990,375September 15, 2017March 31, 2025HUANG, LOTIEN RICHARDreporter.nih.gov
Local regulation and deletion of T cells to induce tolerance and establish long-term survival of high-risk corneal transplantsNIHNational Eye Institute2021 to 2025$1,990,241April 1, 2020February 28, 2030LEVY, ROBERT BENJAMINreporter.nih.gov
Single-cell RNA sequencing reveals novel regulatory pathways in maintaining limbal epithelial stem cell homeostasisNIHNational Eye Institute2021 to 2025$1,988,000September 1, 2021July 31, 2026PENG, HANreporter.nih.gov
Greatly Extended Subzero Ischemic Storage of Renal Allografts Using Novel Bio-inspired Next Generation CryoprotectantsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$1,986,927August 1, 2023May 31, 2026KLINE, MARK Areporter.nih.gov
Developing photoreceptor repair for macular degeneration therapy.NIHNational Eye Institute2021 to 2025$1,986,308September 30, 2021July 31, 2026SINGH, MANDEEPreporter.nih.gov
Transcriptional Regulation of Endothelial Cells after Neonatal Lung InjuryNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,984,340April 1, 2018June 30, 2027KALINICHENKO, VLADIMIRreporter.nih.gov
Metabolic regulation of stem cell niche development and functionNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,984,032July 1, 2022May 31, 2026QU, CHENG-KUIreporter.nih.gov
Scaffolds with high oxygen content for mineralizationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$1,982,762August 1, 2021July 31, 2027CAMCI-UNAL, GULDENreporter.nih.gov
Embryonic Stem Cell Therapy after Cervical Contusion SCI in NHPsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,982,569February 1, 2023January 31, 2028ROSENZWEIG, EPHRON SOLOMONreporter.nih.gov
Improving marginal allograft outcomes through cell junction stabilization in transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,981,284April 15, 2020March 31, 2024GREK, CHRISTINAreporter.nih.gov
InflammaGut: a drug-screenable co-culture system using gut-associated lymphocytes and autologous primary human gut epithelium that reports inflammationNIHNational Center for Advancing Translational Sciences2022 to 2023$1,980,716May 1, 2022January 31, 2025THELIN, BILLreporter.nih.gov
Translating Novel Peripheral Nerve Allograft Technologies Toward Clinical UseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,980,377May 1, 2023April 30, 2027BITTNER, GEORGE DAVISreporter.nih.gov
Delirium in Children Undergoing Hematopoietic Stem Cell TransplantsNIHNational Cancer Institute2021 to 2024$1,975,976September 1, 2020May 31, 2026TRAUBE, CHANIreporter.nih.gov
A recombinant matrix to improve autologous tissue graftsNIHNational Cancer Institute2022 to 2023$1,972,696September 11, 2019June 30, 2025ROBERTS, STEFANreporter.nih.gov
Engineered Neuroprotective Stem-Cell Exosomes for In Utero Spina Bifida TherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,972,069September 30, 2020August 31, 2025FARMER, DIANA LEEreporter.nih.gov
Human Dopamine Grafts in Alpha-Synuclein Models of Parkinson DiseaseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,967,447July 1, 2023June 30, 2028TABAR, VIVIANEreporter.nih.gov
Racial disparities in access to kidney transplantationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,967,199December 6, 2017March 31, 2029KU, ELAINEreporter.nih.gov
Development of platforms for sorting, production, editing of beta cellsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,966,825September 5, 2023April 30, 2028CHOUDHARY, AMITreporter.nih.gov
Choriocapillaris Protection and Replacement in AMDNIHNational Eye Institute2021 to 2025$1,966,287August 1, 2014December 31, 2027MULLINS, ROBERT FOSTERreporter.nih.gov
Urgent and unmet need for a long-term solution for increasing pediatric heart-failure population: BiVACOR Rotary Total Artificial HeartNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,965,590August 5, 2021July 31, 2025TIMMS, DANIELreporter.nih.gov
Isochoric Pressure Based Preservation of Ovarian TissueNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$1,958,572September 26, 2016September 30, 2023WEEGMAN, BRADLEY Preporter.nih.gov
Targeting Immune-Responsive Gene 1 (Irg1) and Itaconate for Cardioprotection of the Donor Heart for TransplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,957,180August 1, 2023July 31, 2027TANG, PAULreporter.nih.gov
Vascular Regeneration with Human Pluripotent Stem Cell-derived Vascular Cells and Engineering ApproachesNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,956,185January 15, 2022December 31, 2025YOON, YOUNG-SUPreporter.nih.gov
Transfer of vaccine-induced immunity from immunocompetent stem cell donor as antiviral immunotherapy to protect high-risk transplant recipients from cytomegalovirus reactivationNIHNational Cancer Institute2023 to 2025$1,953,422May 2, 2023April 30, 2028DIAMOND, DON Jreporter.nih.gov
Tumor matrix remodeling in anti-myeloma immunity and immunotherapyNIHNational Cancer Institute2021 to 2024$1,950,659July 1, 2020December 31, 2024ASIMAKOPOULOS, FOTIOSreporter.nih.gov
DOT1L, reconstitution of plasmacytoid dendritic cells and alloimmunityNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,948,900November 23, 2021March 31, 2026ZHANG, YIreporter.nih.gov
VisR Ultrasound for Monitoring Antibody-Mediated Rejection in Renal Transplant PatientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,948,258March 1, 2016November 30, 2027GALLIPPI, CATERINA Mreporter.nih.gov
Conformal islet encapsulation for transplantation at vascularized sites to allow physiological insulin secretionNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,946,597July 5, 2016February 28, 2029TOMEI, ALICEreporter.nih.gov
Enhanced supercooling for extending non-freezing preservation in preclinical porcine and human donor liversNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,946,161September 17, 2024June 30, 2027TAYLOR, MICHAEL JOHNreporter.nih.gov
Microbiota Regulation of Pulmonary Complications Post-HCTNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,941,600September 20, 2021August 31, 2026ZHOU, XIAOFENGreporter.nih.gov
Improving Utilization of Live Donor Kidney Transplant through Effective Patient-Provider CommunicationNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,936,004June 5, 2023May 31, 2027SIMINOFF, LAURA A.reporter.nih.gov
Identifying the superior ossification pathway for tissue engineered approaches to long bone repairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,932,353April 1, 2021February 28, 2026LEACH, J. KENTreporter.nih.gov
Cryopreservation and nanowarming enables whole liver banking for transplantation, cell therapy and biomedical researchNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,931,299February 15, 2023January 31, 2027FINGER, ERIK BRIANreporter.nih.gov
Targeting Nuclear HSF1 as a Novel Anti-HCMV StrategyNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,927,488January 10, 2023December 31, 2027CHAN, GARY CHING TAOreporter.nih.gov
Development and validation of novel mouse models and expression vectors for characterizing severe alpha-thalassemia pathophysiology and evaluating gene therapy approaches.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,927,121June 1, 2023May 31, 2027RIVELLA, STEFANOreporter.nih.gov
Developing novel therapies to improve blood stem cell transplantation outcomesNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,922,704April 26, 2023April 30, 2027GARZON, RAMIROreporter.nih.gov
Impact of Microbiota on Alloimmune Responses in TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,921,704November 3, 2014November 30, 2025ALEGRE, MARIA-LUISAreporter.nih.gov
Derivation of Functional Spermatogonia Stem Cells from Rhesus Macaque iPSCsNIHOffice of the Director, National Institutes of Health2021 to 2022$1,921,633September 9, 2019June 30, 2024EASLEY, CHARLES A.reporter.nih.gov
Donor Kidney Resident Macrophages in Kidney Allograft Early Inflammation and AlloimmunityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,919,356April 1, 2022February 28, 2027LUO, XUNRONGreporter.nih.gov
Wound healing mechanisms by distinct oral fibroblast populationNIHNational Institute of Dental & Craniofacial Research2021 to 2025$1,917,814April 1, 2021March 31, 2027KO, KANG Ireporter.nih.gov
Development of a Bio-tissue Oxygenation Nanophosphor Enabled Sensing (BONES) system for Quantifying Hypoxia in Bone MarrowNIHNational Institute of General Medical Sciences2021 to 2023$1,915,320June 1, 2021February 28, 2025YUN, WENBINGreporter.nih.gov
Synthetic rescue of antigen-driven T cells and alloimmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,912,839August 12, 2019December 31, 2023SOBOLOFF, JONATHAN Areporter.nih.gov
Biomaterials to enhance the efficacy of MSCs for rotator cuff repairNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,908,567July 1, 2021April 30, 2027TEMENOFF, JOHNNA Sreporter.nih.gov
The Role of Donor Innate Immune Responses in Regulating Alloimmunity after Heart TransplantationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,907,359June 1, 2020May 31, 2025KREISEL, DANIELreporter.nih.gov
THE NNTC COLLECTS, STORE, AND PROVIDE CLINICAL DATA AND WELL CHARACTERIZED BIOLOGICAL SPECIMENS, INCLUDING POST-MORTEM TISSUE FROM STUDY VOLUNTEERS AND/OR ORGAN DONORS WITH HIV AS WELL AS HIV-NEGATIVENIHNational Institute of Mental Health2023 to 2025$1,905,501August 23, 2023August 22, 2026GELMAN, BENJAMINreporter.nih.gov
Genetic engineering of kidney allografts by ex vivo perfusion delivery of adeno-associated viral vectorsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,903,303July 19, 2022April 30, 2027BARBAS, ANDREW SERGHIOSreporter.nih.gov
The Impact of Donor Diabetes on Corneal Immune Cells and Graft SurvivalNIHNational Eye Institute2022 to 2025$1,896,125September 30, 2022August 31, 2027DANA, REZAreporter.nih.gov
Informing Ethical Translation of Xenotransplantation Clinical TrialsNIHNational Center for Advancing Translational Sciences2021 to 2024$1,895,092August 9, 2021July 31, 2025MASCHKE, KAREN JOANNreporter.nih.gov
Home-based Autologous Hematopoietic Stem Cell Transplantation to Improve Outcomes and Decrease CostsNIHNational Institute on Aging2021 to 2024$1,889,750June 1, 2020June 1, 2024SUNG, ANTHONYreporter.nih.gov
An Advanced Dermal Regeneration Scaffold for Reconstructive SurgeryNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,887,448August 15, 2023July 31, 2025SAPIR LEKHOVITSER, YULIAreporter.nih.gov
Optimization of the engineered 3D hepatic microenvironment enhances pluripotent stem cell derived hepatocyteNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$1,887,016February 1, 2020January 31, 2026SCHWARTZ, ROBERT Ereporter.nih.gov
Improving Aged Neuromuscular Health and FunctionNIHNational Institute on Aging2022 to 2025$1,878,947June 1, 2022March 31, 2027LAVASANI, MITRAreporter.nih.gov
T Cell Memory in Organ TransplantationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,873,569February 1, 2001April 30, 2026LAKKIS, FADI G.reporter.nih.gov
The Cardiac Atlas ProjectNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,871,310January 1, 2014June 30, 2025MCCULLOCH, ANDREW D.reporter.nih.gov
Cell-free vascular grafts: immunological response and vascular regenerationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,868,150April 10, 2020March 31, 2026ANDREADIS, STELIOS THEOHARISreporter.nih.gov
Combination Gene Therapy for Treatment of Canine Mucopolysaccharidosis Type INIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,867,960May 5, 2023February 29, 2028WANG, RAYMOND YU JEANGreporter.nih.gov
Development of Tissue Engineered Neuromuscular Interfaces from GalSafe NeuronsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,866,060January 15, 2022March 31, 2027KATIYAR, KRITIKAreporter.nih.gov
Peri-operative factors that drive cell-free hemoglobin-mediated primary graft dysfunctionNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,864,753August 5, 2022July 31, 2027SHAVER, CIARA Mreporter.nih.gov
Establishment of a First-in-Class Biocompatible and Efficient Cryopreservation Technology Platform for the Next Generation of Cell-Based Therapeutics in Regenerative Medicine and Drug DiscoveryNIHOffice of the Director, National Institutes of Health2024 to 2025$1,863,241September 15, 2024August 31, 2026HAN, XUreporter.nih.gov
Long-term Outcomes after Interventions for Congenital Heart DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2022$1,858,355April 1, 2014July 31, 2025KOCHILAS, LAZAROS K.reporter.nih.gov
Developing Machine Learning Models for Decision Support and Allocation Optimization in Heart TransplantationNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,857,171September 4, 2023March 31, 2027KILIC, ARMANreporter.nih.gov
Lymph Node Structure and Function in Tolerance: Role of LamininsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,854,000April 20, 2015May 31, 2025BROMBERG, JONATHAN Sreporter.nih.gov
Reprogramming reactive glial cells into functional new neurons after SCINIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,850,333August 1, 2020February 28, 2025WU, WEIreporter.nih.gov
Development of Stem Cell-based Therapies for Limbal Stem Cell DeficiencyNIHNational Eye Institute2021 to 2025$1,848,661September 1, 2012March 31, 2030DENG, SOPHIEreporter.nih.gov
Laryngotracheal Reconstruction with Engineered CartilageNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,843,394April 15, 2023February 28, 2027GOTTARDI, RICCARDOreporter.nih.gov
Multimodal approach investigating the immunomodulatory effect ofneural stem cells in stroke recoveryNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,840,475August 1, 2008January 31, 2026STEINBERG, GARY Kreporter.nih.gov
The role of bile acid metabolomics in graft-versus-host diseaseNIHNational Cancer Institute2021 to 2023$1,838,884April 1, 2018October 16, 2023VAN DEN BRINK, MARCEL R Mreporter.nih.gov
Development of a Novel Engineered Tendon Graft to Assist in Repair of Rotator Cuff InjuriesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,836,877July 1, 2023May 31, 2026LARKIN, LISA Mreporter.nih.gov
Multifaceted Intervention to Improve Graft Outcome Disparities in African American Kidney Transplants (MITIGAAT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,835,791July 1, 2023May 31, 2028TABER, DAVID J.reporter.nih.gov
Generation of Tissue Engineered Nerve Grafts from GalSafe Porcine NeuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,835,055September 30, 2018August 31, 2024KATIYAR, KRITIKAreporter.nih.gov
Circadian Signatures in Chronic Lung DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,833,797August 1, 2020May 31, 2025HASPEL, JEFFREY ADAMreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of PennsylvaniaPhiladelphia, PA81$107 million0$0
Duke UniversityDurham, NC50$94 million0$0
Medical College of WisconsinMilwaukee, WI22$92.7 million0$0
Stanford UniversityStanford, CA86$89.6 million0$0
Johns Hopkins UniversityBaltimore, MD69$88.7 million0$0
University of California, San FranciscoSan Francisco, CA68$85.3 million0$0
Massachusetts General HospitalBoston, MA52$76.9 million0$0
Fred Hutchinson Cancer CenterSeattle, WA39$69.1 million0$0
Boston Children's HospitalBoston, MA34$68.7 million0$0
Columbia University Health SciencesNew York, NY39$66.4 million0$0
Northwestern University at ChicagoChicago, IL35$64 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA59$64 million0$0
University of MinnesotaMinneapolis, MN39$56.4 million0$0
Brigham and Women's HospitalBoston, MA39$52.3 million0$0
University of Michigan at Ann ArborAnn Arbor, MI49$48.8 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH32$45.4 million0$0
University of WashingtonSeattle, WA32$45.1 million0$0
Emory UniversityAtlanta, GA46$42.1 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA26$40.6 million0$0
Vanderbilt University Medical CenterNashville, TN24$39.6 million0$0
Washington UniversitySaint Louis, MO44$38.7 million0$0
New York University School of MedicineNew York, NY35$37.4 million0$0
University of Alabama at BirminghamBirmingham, AL22$36.7 million0$0
University of California Los AngelesLos Angeles, CA36$34.2 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH21$34 million0$0
Beckman Research Institute/city of HopeDuarte, CA23$33.1 million0$0
Indiana University IndianapolisIndianapolis, IN30$31.4 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA12$29.4 million0$0
University of California, San DiegoLa Jolla, CA27$26.9 million0$0
PPD Development LPWilmington, NC1$26.7 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY26$26.4 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY19$25.4 million0$0
Mayo Clinic RochesterRochester, MN28$24.3 million0$0
Weill Medical Coll of Cornell UnivNew York, NY21$23.3 million0$0
University of Colorado DenverAurora, CO25$23.1 million0$0
Ohio State UniversityColumbus, OH18$21.7 million0$0
University of California-IrvineIrvine, CA15$21.7 million0$0
University of Maryland BaltimoreBaltimore, MD20$21.1 million0$0
University of FloridaGainesville, FL25$20.8 million0$0
University of Connecticut SCH of Med/dntFarmington, CT8$20.5 million0$0
Wake Forest University Health SciencesWinston-Salem, NC11$20.2 million0$0
Methodist Hospital Research InstituteHouston, TX13$20.1 million0$0
University of Wisconsin-MadisonMadison, WI23$19.7 million0$0
Yale UniversityNew Haven, CT24$18 million0$0
Baylor College of MedicineHouston, TX16$16.8 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA12$16.7 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC12$16.6 million0$0
Medical University of South CarolinaCharleston, SC16$15 million0$0
University of Southern CaliforniaLos Angeles, CA9$14.7 million0$0
ST. Jude Children's Research HospitalMemphis, TN14$13.5 million0$0
Georgia Tech Research CorporationAtlanta, GA12$13.4 million0$0
Oregon Health & Science UniversityPortland, OR11$12.6 million0$0
University of Texas at San AntonioSan Antonio, TX2$12.5 million0$0
University of ChicagoChicago, IL12$11.8 million0$0
University of Miami School of MedicineCoral Gables, FL12$11.6 million0$0
Cornell UniversityIthaca, NY7$11.4 million0$0
University of TX MD Anderson Can CTRHouston, TX12$10.8 million0$0
Dana-Farber Cancer InstBoston, MA9$10.8 million0$0
Schepens Eye Research InstituteBoston, MA11$10.7 million0$0
SUNY at BuffaloAmherst, NY9$10.6 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX9$10 million0$0
Research Inst Nationwide Children's HospColumbus, OH11$9.8 million0$0
Case Western Reserve UniversityCleveland, OH9$9.7 million0$0
University of Illinois at ChicagoChicago, IL10$9.7 million0$0
Mclean HospitalBelmont, MA2$9.6 million0$0
University of Texas at DallasRichardson, TX1$9.3 million0$0
Ut Southwestern Medical CenterDallas, TX12$8.8 million0$0
University of RochesterRochester, NY11$8.7 million0$0
Fred Hutchinson Cancer Research CenterSeattle, WA22$8.6 million0$0
Brown UniversityProvidence, RI4$8.5 million0$0
University of California at DavisDavis, CA12$8.4 million0$0
Beth Israel Deaconess Medical CenterBoston, MA6$8.2 million0$0
North Carolina State UniversityRaleigh, NC11$8.2 million0$0
University of VirginiaCharlottesville, VA5$7.9 million0$0
Technical Resources International, Inc.Bethesda, MD1$7.8 million0$0
University of IowaIowa City, IA9$7.7 million0$0
Harvard UniversityCambridge, MA4$7.7 million0$0
Lurie Children's Hospital of ChicagoChicago, IL4$7.6 million0$0
Seattle Children's HospitalSeattle, WA7$7.4 million0$0
Rogosin InstituteNew York, NY1$7.4 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA7$6.9 million0$0
Sylvatica Biotech, Inc.North Charleston, SC4$6.8 million0$0
Pharmain CorporationBothell, WA1$6.8 million0$0
Bivacor, Inc.Houston, TX3$6.5 million0$0
University of Kansas Medical CenterKansas City, KS8$6.5 million0$0
Children's Research InstituteWashington, DC5$6.3 million0$0
University of ConnecticutStorrs, CT6$6.2 million0$0
University of ArizonaTucson, AZ5$6.2 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ8$6.2 million0$0
Arizona State UniversityScottsdale, AZ6$5.9 million0$0
Mayo Clinic ArizonaScottsdale, AZ6$5.7 million0$0
Albert Einstein College of MedicineBronx, NY10$5.6 million0$0
Roswell Park Cancer Institute CorpBuffalo, NY4$5.5 million0$0
Magee-Women's Res Inst and FoundationPittsburgh, PA4$5.4 million0$0
University of California-San Diego Scripps Inst of OceanographyLa Jolla, CA1$5.4 million0$0
Hennepin Healthcare Research InstituteMinneapolis, MN7$5.2 million0$0
Expanse Bio LLCNorth Charleston, SC3$5.1 million0$0
University of UtahSalt Lake City, UT7$5 million0$0
University of Colorado at BoulderBoulder, CO5$4.9 million0$0
Cryocrate, LLCColumbia, MO3$4.8 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20251,042$628,532,5250$0
20241,071$577,612,4880$0
20231,102$587,372,7210$0
20221,123$544,630,6580$0
20211,141$548,094,7730$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 24 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 5 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 5 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIHJuly 17, 2027Not listedNotice number printed on 1 award here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 431 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 431 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 431 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 431 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 431 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 431 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 431 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 431 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 431 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 431 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 431 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 431 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.