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Data / Research funding / Substance Misuse

Substance Misuse: 7,804 NIH awards ($10.8B) to 842 organizations

7,804 NIH awards ($10.8B) in the NIH spending category Substance Misuse, to 842 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 7,804 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
HIV Prevention Trials Network Leadership and Operations CenterNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$213,590,410June 1, 2006November 30, 2027COHEN, MYRON SCOTTreporter.nih.gov
NIDA Clinical Trials Network: New York Node (CTN-0139, CTN-0155, CTN-Biostats)NIHNational Institute on Drug Abuse2021 to 2025$66,452,521March 1, 2025February 29, 2032MCNEELY, JENNIFERreporter.nih.gov
CTN New England Consortium NodeNIHNational Institute on Drug Abuse2021 to 2025$58,365,118March 1, 2025February 29, 2032D'ONOFRIO, GAILreporter.nih.gov
NIDA Clinical Trials Network: Big South/West Node (CTN-0132 and CTN-0139)NIHNational Institute on Drug Abuse2021 to 2025$43,417,361March 1, 2025February 28, 2032TRIVEDI, MADHUKAR H.reporter.nih.gov
LC: HIV PREVENTION TRIALS NETWORKNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$40,489,166June 1, 2006November 30, 2027ESHLEMAN, SUSAN Hreporter.nih.gov
Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)NIHNational Institute on Drug Abuse2021 to 2022$36,092,167April 17, 2019March 31, 2025WALSH, SHARON L.reporter.nih.gov
Collaborative Study on the Genetics of Alcoholism (COGA).NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$34,320,125September 29, 1989August 31, 2029PORJESZ, BERNICEreporter.nih.gov
FY25 AWARD. NIDA DEVELOPMENTAL STUDIES BIOREPOSITORY AND ANALYSIS CENTER. SEPTEMBER 17, 2025 - SEPTEMBER 16, 2026. N01DA-21-5588. TASK ORDER 75N95025F00001 (TO5).NIHNational Institute on Drug Abuse2021 to 2025$34,168,377September 17, 2025September 16, 2026reporter.nih.gov
CCC TO 11 - CTN-0145: STANDARD VERSUS HIGH DOSE ED-INITIATED BUPRENORPHINE INDUCTION. POP: 8/28/23 - 8/27/27.NIHNational Institute on Drug Abuse2021 to 2025$33,434,913August 28, 2023August 27, 2026JELSTROM, EVEreporter.nih.gov
CHASE: An Innovative County-Level Public Health Response to the Opioid Epidemic in New York StateNIHNational Institute on Drug Abuse2021 to 2023$32,731,263September 15, 2023March 31, 2024EL-BASSEL, NABILAreporter.nih.gov
MassHEAL - Reducing overdose deaths by 40% (2019-2023)NIHNational Institute on Drug Abuse2021 to 2023$29,970,213September 15, 2023March 31, 2024SAMET, JEFFREY H.reporter.nih.gov
BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination ImmunotherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$29,083,069August 16, 2021April 30, 2027MONTANER, LUIS Jreporter.nih.gov
Monitoring the Future: Drug Use & Lifestyles of American Youth (Supp1: Nicotine Pouch and E-cigarette Use Among US Adolescents: National Estimates of Brand Use and Flavor Preferences)NIHNational Institute on Drug Abuse2021 to 2025$29,078,476June 28, 1975March 31, 2027MIECH, RICHARD Areporter.nih.gov
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Core ProjectNIHNational Institute on Aging2021 to 2025$28,336,705March 1, 2021December 31, 2026HUMMER, ROBERT Areporter.nih.gov
RADX BLUEPRINT MEDTECH TRANSLATOR COHORT 2 - COMMERCIALIZATION CENTER - HEALNIHNational Heart, Lung, and Blood Institute2022 to 2025$27,543,152June 2, 2025June 1, 2026reporter.nih.gov
REACH: Research Enterprise to Advance a Cure for HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$27,533,114August 16, 2021April 30, 2027JONES, R. BRADreporter.nih.gov
Delaney AIDS Research Enterprise to Cure HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$26,967,938August 16, 2021April 30, 2027DEEKS, STEVEN GRANTreporter.nih.gov
The Florida Node Alliance of the National Drug Abuse Clinical Trials Network (CTN-121)NIHNational Institute on Drug Abuse2021 to 2025$26,301,696March 1, 2025February 29, 2028SZAPOCZNIK, JOSEreporter.nih.gov
Collaboratory of AIDS Researchers for Eradication (CARE)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$26,234,170August 16, 2021April 30, 2027MARGOLIS, DAVID M.reporter.nih.gov
Optimizing HEALing in Ohio Communities (OHiO)-Health Equity SupplementNIHNational Institute on Drug Abuse2021 to 2023$25,859,414September 15, 2023March 31, 2024FREISTHLER, BRIDGET Jreporter.nih.gov
DSC MANAGEMENT AND SUPPORT. MARCH 1, 2025 TO FEBRUARY 28, 2026. N01DA-22-2253. TASK ORDER NO. 75N95025F00001 (TO25).NIHNational Institute on Drug Abuse2022 to 2025$25,789,598March 1, 2025February 28, 2026reporter.nih.gov
Data Coordinating Center (DCC) for the Neonatal Opioid Withdrawal Syndrome Pharmacological Treatments Comparative Effectiveness Trial (NOWS PhaCET)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$25,628,714September 20, 2021August 31, 2027DAS, ABHIKreporter.nih.gov
ERASE HIV: Enterprise for Research and Advancements to Stop and Eradicate HIVNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$25,334,968August 16, 2021June 12, 2026PAIARDINI, MIRKOreporter.nih.gov
Center for Chronic Disease Reduction and Equity Promotion Across Minnesota (C2DREAM)NIHNational Institute on Minority Health and Health Disparities2021 to 2025$24,809,662September 24, 2021December 31, 2026ALLEN, MICHELE Lreporter.nih.gov
ABCD-USA Consortium: Coordinating CenterNIHNational Institute on Drug Abuse2021 to 2025$24,150,007September 30, 2015March 31, 2027JERNIGAN, TERRY L.reporter.nih.gov
Data Analysis and Coordination Center for the MACS-WIHS Combined Cohort StudyNIHNational Heart, Lung, and Blood Institute2021 to 2025$23,837,604April 9, 2019September 30, 2026GANGE, STEPHEN Jreporter.nih.gov
SDMC: HIV Prevention Trials NetworkNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$23,565,144June 29, 2006March 31, 2022DONNELL, DEBORAH Jreporter.nih.gov
I4C 2.0: Immunotherapy for CureNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$23,329,181August 16, 2021April 30, 2027BAROUCH, DAN H.reporter.nih.gov
SF Bay Area MACS/WIHS Combined Cohort StudyNIHNational Heart, Lung, and Blood Institute2021 to 2025$23,128,905April 1, 2019September 30, 2026TIEN, PHYLLIS Creporter.nih.gov
NorthStar Node of the NIDA Clinical Trials NetworkNIHNational Institute on Drug Abuse2021 to 2025$22,374,119September 1, 2015February 29, 2032BART, GAVINreporter.nih.gov
Los Angeles CRS for the MACS/WIHS Combined Cohort StudyNIHNational Heart, Lung, and Blood Institute2021 to 2025$22,107,486April 15, 2019September 30, 2026MIMIAGA, MATTHEW JAMESreporter.nih.gov
University of Pittsburgh MACS/WIHS CCSNIHNational Heart, Lung, and Blood Institute2021 to 2025$21,988,029April 1, 2019September 30, 2026RINALDO, CHARLES Rreporter.nih.gov
UCLA AIDS Prevention and Treatment Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,546,764February 1, 2007November 30, 2027LANDOVITZ, RAPHAEL Jreporter.nih.gov
SCREENING OF INVESTIGATIONAL AGENTS THROUGH THE NINDS PRECLINICAL SCREENING PLATFORM FOR PAIN (PSPP)NIHNational Institute on Drug Abuse2024 to 2025$21,254,211September 6, 2024September 5, 2026HANANIA, TALEENreporter.nih.gov
A Strategy for Heal Federated Data EcosystemNIHOffice of the Director, National Institutes of Health2021 to 2025$21,063,286February 18, 2021April 30, 2026GOSWAMI, SUPARNAreporter.nih.gov
Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS)NIHNational Heart, Lung, and Blood Institute2021 to 2025$21,023,937April 1, 2019September 30, 2026SHARMA, ANJALIreporter.nih.gov
Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC CenterNIHNational Heart, Lung, and Blood Institute2021 to 2025$21,007,836April 1, 2019September 30, 2026MARGOLICK, JOSEPH B.reporter.nih.gov
ABCD-USA Consortium: Data Analysis, Informatics and Resource CenterNIHNational Institute on Drug Abuse2021 to 2024$20,902,844September 30, 2015March 31, 2025DALE, ANDERS Mreporter.nih.gov
Yale Center for the Study of Tobacco Product Use and Addiction (YCSTP)NIHNational Institute on Drug Abuse2021 to 2025$20,420,182September 30, 2013August 31, 2028KRISHNAN-SARIN, SUCHITRAreporter.nih.gov
Northwestern CORE Clinical Research Site: Trans-omics for HIV/AIDS ResearchNIHNational Heart, Lung, and Blood Institute2021 to 2025$19,790,656April 10, 2019September 30, 2026WOLINSKY, STEVEN Mreporter.nih.gov
North American AIDS Cohorts on Collaboration and Design (NAACCORD)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$19,377,019July 1, 2006April 30, 2027ALTHOFF, KERI NICOLEreporter.nih.gov
A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$18,851,827September 25, 2020March 31, 2027HAVLIR, DIANE Vreporter.nih.gov
JCOIN Phase II Coordination and Translation CenterNIHNational Institute on Drug Abuse2021 to 2025$18,785,790September 30, 2019May 31, 2029TAXMAN, FAYE Sreporter.nih.gov
The Ohio Valley Node of the Clinical Trials Network (CTN-0153)NIHNational Institute on Drug Abuse2021 to 2025$18,588,752March 1, 2025February 29, 2032WINHUSEN, T JOHNreporter.nih.gov
Northeast Node of the National Drug Abuse Treatment Clinical Trials NetworkNIHNational Institute on Drug Abuse2021 to 2025$17,509,561March 1, 2025February 28, 2030MARSCH, LISA A.reporter.nih.gov
8/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT CHLANIHNational Institute on Drug Abuse2021 to 2025$16,425,086September 30, 2015July 31, 2026SOWELL, ELIZABETH Rreporter.nih.gov
CWRU Center for Excellence on the Impact of Substance Use on HIVNIHNational Institute on Drug Abuse2021 to 2025$16,213,687September 15, 2021May 31, 2027LEVINE, ALAN DAVIDreporter.nih.gov
University of Pennsylvania HIV Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,198,927February 1, 2007November 30, 2027FRANK, IANreporter.nih.gov
MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS)NIHNational Heart, Lung, and Blood Institute2021 to 2025$15,678,563April 1, 2019September 30, 2026FRENCH, AUDREYreporter.nih.gov
HEALing Communities Study Health Equity ResearchNIHNational Institute on Drug Abuse2021 to 2023$15,117,207April 1, 2019September 29, 2024OGA, EMMANUEL AJAreporter.nih.gov
Atlanta MACS/WIHS Combined Cohort Study Clinical Research SiteNIHNational Heart, Lung, and Blood Institute2021 to 2025$15,081,381April 1, 2019September 30, 2026LAHIRI, CECILE DELILLEreporter.nih.gov
UAB-MISS MACS/WIHS Combined Cohort StudyNIHNational Heart, Lung, and Blood Institute2021 to 2025$14,601,685April 1, 2019September 30, 2026KEMPF, MIRJAM-COLETTEreporter.nih.gov
Single cell transcriptomic and epigenomic changes during chronic HIV infection and cocaine self-administrationNIHNational Institute on Drug Abuse2022 to 2025$14,516,969June 1, 2022March 31, 2027ZENG, HONGKUIreporter.nih.gov
Surviving the HIV Epidemic (S/HE) in metropolitan Washington DC - Advancing knowledge through cohort studiesNIHNational Heart, Lung, and Blood Institute2021 to 2025$14,413,637April 1, 2019September 30, 2026KASSAYE, SEBLE Greporter.nih.gov
IeDEA Asia-Pacific Research CollaborationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,360,741July 15, 2006April 30, 2027SOHN, ANNETTE Hreporter.nih.gov
NIDA DATA, STATISTICS, AND CLINICAL TRIAL SUPPORT CENTER MANAGEMENT AND SUPPORT. 03/01/2022 - 02/28/2023. N01DA-19-2250. TASK ORDER 75N95022F00001 (TONIHNational Institute on Drug Abuse2021 to 2022$14,328,957March 1, 2022February 28, 2023MCCORMACK, JENNIFERreporter.nih.gov
The RADAR cohort study of multilevel Influences on HIV and substance useNIHNational Institute on Drug Abuse2021 to 2025$14,251,651April 15, 2014April 30, 2030MUSTANSKI, BRIANreporter.nih.gov
MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS)NIHNational Heart, Lung, and Blood Institute2021 to 2025$14,117,524April 1, 2019September 30, 2026GUSTAFSON, DEBORAH R.reporter.nih.gov
UNC MACS/WIHS Combined Cohort Study Clinical Research SiteNIHNational Heart, Lung, and Blood Institute2021 to 2025$13,957,792April 1, 2019September 30, 2026FLORIS-MOORE, MICHELLEreporter.nih.gov
OUTLAST - A First Multiple-Dose Efficacy Study of IXT-m200, an anti-METH Monoclonal Antibody, in Patients with METH Use DisorderNIHNational Institute on Drug Abuse2021 to 2023$13,778,020September 30, 2021July 31, 2025STEVENS, MISTY WARDreporter.nih.gov
Arylepoxamides: A new class of potent, safer analgesicsNIHNational Institute on Drug Abuse2021 to 2023$13,729,307December 15, 2018August 31, 2025REICH, JEFFREYreporter.nih.gov
Integrated Care for Chronic Pain and Opioid Use Disorder: The IMPOWR Research Center at Montefiore/Einstein (IMPOWR-ME)NIHNational Institute on Drug Abuse2021 to 2025$13,727,424September 30, 2021July 31, 2027STARRELS, JOANNA L.reporter.nih.gov
1/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U UTAHNIHNational Institute on Drug Abuse2021 to 2025$13,649,176September 30, 2015March 31, 2027YURGELUN-TODD, DEBORAH A.reporter.nih.gov
TO4. CLINICAL COORDINATING CENTER FOR NIDA'S CLINICAL TRIALS NETWORK. CONTRACT TYPE: IDIQ TASK ORDER. POP: 8/15/24 - 8/14/29NIHNational Institute on Drug Abuse2024 to 2025$13,234,516July 16, 2025July 15, 2026reporter.nih.gov
BRAIN CONNECTS: The center for Large-scale Imaging of Neural Circuits (LINC)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$13,208,545September 1, 2023June 30, 2028YENDIKI, ANASTASIAreporter.nih.gov
IND-enabling Studies in Support of First in Human Safety Studies of a Novel Anti-Nicotine Human Monoclonal AntibodyNIHNational Institute on Drug Abuse2023 to 2025$13,125,765May 1, 2023April 30, 2027KALNIK, MATTHEW Wreporter.nih.gov
MACS/WIHS -CCSNIHNational Heart, Lung, and Blood Institute2021 to 2025$12,990,830April 1, 2019September 30, 2026ALCAIDE, MARIA LUISAreporter.nih.gov
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research CentersNIHNational Institute on Drug Abuse2021 to 2025$12,902,047September 30, 2021July 31, 2026BECKER, WILLIAM Creporter.nih.gov
Helping to End Addiction Long-term (HEAL) Data PlatformNIHOffice of the Director, National Institutes of Health2022 to 2025$12,729,883September 1, 2025August 31, 2026GROSSMAN, ROBERT L.reporter.nih.gov
Supporting Treatment Access and Recovery for Co-Occurring Opioid Use and Mental Health Disorders (STAR-COD)NIHNational Institute of Mental Health2021 to 2024$12,719,359September 16, 2021August 31, 2025SMELSON, DAVID Areporter.nih.gov
Tailored Retention and Engagement for Effective integrated Treatment of OUD and Pain (TREETOP)NIHNational Institute on Drug Abuse2021 to 2025$12,656,947September 30, 2021July 31, 2027WINSTANLEY, ERIN Lreporter.nih.gov
Single Cell Transcriptomic and Epigenomic Dissection of Opioid and Cocaine Responses in HIVNIHNational Institute on Drug Abuse2021 to 2025$12,564,620September 1, 2021June 30, 2027KELLIS, MANOLISreporter.nih.gov
Monitoring the Future: A Cohort-Sequential Panel Study of Drug Use, Ages 19-65NIHNational Institute on Drug Abuse2021 to 2025$12,535,708September 30, 2003March 31, 2027PATRICK, MEGAN E.reporter.nih.gov
Center for Addiction and Disease Risk ExacerbationNIHNational Institute of General Medical Sciences2021 to 2025$12,487,946August 1, 2019July 31, 2029MONTI, PETER M.reporter.nih.gov
The Y-SCORCH Data Generation Center at Yale for Single-Cell Opioid Responses in the Context of HIVNIHNational Institute on Drug Abuse2021 to 2025$12,331,452August 1, 2020July 31, 2026SPUDICH, SERENA Sreporter.nih.gov
AIDS Linked to the IntraVenous Experience (ALIVE) StudyNIHNational Institute on Drug Abuse2021 to 2025$12,226,379January 1, 2014May 31, 2030MEHTA, SHRUTI Hreporter.nih.gov
Phase III double-blind, randomized controlled trial of suvorexant versus placebo to treat insomnia in persons with opioid use disorderNIHNational Institute on Drug Abuse2024 to 2025$12,205,195May 15, 2024February 28, 2027HUHN, ANDREW Sreporter.nih.gov
Advancing brain health research through male germline editing in marmosetsNIHNational Institute on Drug Abuse2021 to 2025$12,061,296August 1, 2021May 31, 2027HERMANN, BRIAN PETERreporter.nih.gov
Evaluation of safety and pharmacokinetics of naltrexone implantNIHNational Institute on Drug Abuse2021 to 2023$12,060,583September 15, 2018February 28, 2026BISAGA, ADAMreporter.nih.gov
Clinical Development of a Therapeutic Agent for Rapid Reversal of Methamphetamine IntoxicationNIHNational Institute on Drug Abuse2023 to 2025$11,962,715August 15, 2023June 30, 2026LI, XINHUAreporter.nih.gov
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) - Indiana University Data Coordinating CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$11,773,646August 1, 2018June 30, 2029TU, WANZHUreporter.nih.gov
COBRE Center on Opioids and OverdoseNIHNational Institute of General Medical Sciences2021 to 2025$11,768,169September 1, 2018August 31, 2028RICH, JOSIAH Dreporter.nih.gov
A once-weekly oral methadone for maintenance therapy for opioid use disorderNIHNational Institute on Drug Abuse2021$11,699,793September 30, 2019April 30, 2025SCRANTON, RICHARDreporter.nih.gov
Using Longitudinal Research to Engage African American and Latinx Sexual- and Gender-Minority Youth in the HIV Prevention and Care Continua and Reduce HIV/AIDS-Related DisparitiesNIHNational Institute on Drug Abuse2021 to 2024$11,452,208August 15, 2015June 30, 2025KIPKE, MICHELE D.reporter.nih.gov
Center for Dissemination and Implementation At Stanford (C-DIAS)NIHNational Institute on Drug Abuse2022 to 2025$11,245,029August 1, 2022May 31, 2027MCGOVERN, MARK Preporter.nih.gov
Revealing the single cell determinants of brain relevant to persistent HIV infection and opioid use disorderNIHNational Institute on Drug Abuse2021 to 2025$11,197,081September 30, 2021July 31, 2027RANA, TARIQ Mreporter.nih.gov
5/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$11,114,203September 30, 2021June 30, 2026LIN, WEILIreporter.nih.gov
Single cell brain transcriptome changes during chronic HIV infection and opiate use in conventional miceNIHNational Institute on Drug Abuse2021 to 2025$11,085,606May 15, 2021July 31, 2026KENNY, PAUL J.reporter.nih.gov
Vaccines for fentanyl and its derivatives: A strategy to reduce illicit use and overdoseNIHNational Institute on Drug Abuse2022 to 2024$11,034,562February 1, 2019July 31, 2025PRAVETONI, MARCOreporter.nih.gov
Johns Hopkins University Baltimore India Clinical Trail Unit (JHUBI CTU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,947,708February 5, 2007November 30, 2027GUPTA, AMITAreporter.nih.gov
Center to Advance Research Excellence (OPTIC)NIHNational Institute on Drug Abuse2021 to 2025$10,836,251August 15, 2018June 30, 2028STEIN, BRADLEY Dreporter.nih.gov
5/21 ABCD-USA Consortium: Research Project Site at UC San DiegoNIHNational Institute on Drug Abuse2021 to 2025$10,821,558September 30, 2015March 31, 2027TAPERT, SUSAN F.reporter.nih.gov
Greater Intermountain Node (CTN-0138)NIHNational Institute on Drug Abuse2021 to 2025$10,595,733March 1, 2025February 29, 2032COCHRAN, GERALD T.reporter.nih.gov
Addressing risk through Community Treatment for Infectious disease and Opioid use disorder Now (ACTION) among justice-involved populationsNIHNational Institute on Drug Abuse2021 to 2025$10,550,278September 30, 2020July 31, 2026SPRINGER, SANDRA ANNreporter.nih.gov
Integrative Treatment for Achieving Holistic Recovery from Comorbid Chronic Pain and Opioid Use DisorderNIHNational Institute on Drug Abuse2021 to 2025$10,475,915September 30, 2021July 31, 2027WITKIEWITZ, KATIE Areporter.nih.gov
ICAP Clinical Trials UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,475,165December 1, 2020November 30, 2027EL-SADR, WAFAA M.reporter.nih.gov
9/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MICHIGANNIHNational Institute on Drug Abuse2021 to 2025$10,318,458September 30, 2015March 31, 2027HEITZEG, MARY Mreporter.nih.gov
Cannabidiol in the treatment of opioid use disorderNIHNational Institute on Drug Abuse2024$10,316,590September 30, 2019August 31, 2027HURD, YASMIN L.reporter.nih.gov
6/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium VanderbiltNIHNational Institute on Drug Abuse2021 to 2025$10,312,406September 30, 2021June 30, 2026CUTTING, LAURIE Ereporter.nih.gov
15/21 ABCD-USA Consortium: Research Project Site at LIBRNIHNational Institute on Drug Abuse2021 to 2025$10,302,955April 15, 2020March 31, 2027PAULUS, MARTIN P.reporter.nih.gov
4/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT FIUNIHNational Institute on Drug Abuse2021 to 2025$9,979,334September 30, 2015March 31, 2027GONZALEZ, RAULreporter.nih.gov
IND-enabling program for a long-acting anti-methamphetamine monoclonal antibody for treating methamphetamine use disorderNIHNational Institute on Drug Abuse2022 to 2024$9,900,251September 30, 2022July 31, 2025STEVENS, MISTY WARDreporter.nih.gov
PF614-MPAR: clinical development of opioid with oral overdose protectionNIHNational Institute on Drug Abuse2024 to 2025$9,861,616September 1, 2024May 31, 2027KIRKPATRICK, LYNNreporter.nih.gov
1/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$9,849,650September 30, 2021June 30, 2026OU, XIAWEIreporter.nih.gov
5/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$9,809,065September 30, 2021June 30, 2026GRANT, PATRICIA ELLENreporter.nih.gov
21/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT WUSTLNIHNational Institute on Drug Abuse2021 to 2025$9,776,479April 15, 2020March 31, 2027MADDEN, PAMELA ANNreporter.nih.gov
Select Late-Stage CMC, Non-clinical Studies, and Quality Programs to Accelerate NRS-033 Towards Pivotal Studies and Registration in Opioid Use DisorderNIHNational Institute on Drug Abuse2024 to 2025$9,732,775August 1, 2024May 31, 2027SHAH, NIKEJreporter.nih.gov
Southern Consortium Node of the Clinical Trials Network (TMS for CUD)NIHNational Institute on Drug Abuse2021 to 2025$9,579,585March 1, 2025February 29, 2032BARTH, KELLY S.reporter.nih.gov
4/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$9,532,703September 30, 2021June 30, 2026MERHAR, STEPHANIE Lreporter.nih.gov
M-SCORCH: Methamphetamine use disorder data generation center for Single Cell Opioid Responses in the Context of HIVNIHNational Institute on Drug Abuse2021 to 2025$9,490,616May 15, 2021February 28, 2027HO, YA-CHIreporter.nih.gov
CNS Effects of Alcohol: Cellular NeurobiologyNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$9,489,642December 1, 1983December 31, 2027ROBERTO, MARISAreporter.nih.gov
2/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UMBNIHNational Institute on Drug Abuse2021 to 2025$9,449,174September 30, 2015March 31, 2027ERNST, THOMAS Mreporter.nih.gov
A novel therapeutic to ameliorate chronic pain and reduce opiate useNIHNational Institute on Drug Abuse2021 to 2024$9,323,255March 15, 2019June 30, 2024TABAKOFF, BORISreporter.nih.gov
Environmental Approaches to PreventionNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$9,318,439September 29, 1983November 30, 2027PASCHALL, MALLIE Jreporter.nih.gov
Development of a novel drug for treating opioid use disorderNIHNational Institute on Drug Abuse2022 to 2024$9,160,866March 15, 2019August 31, 2025SHAH, NIKEJreporter.nih.gov
7/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$9,118,437September 30, 2021June 30, 2026VOLK, HEATHER Ereporter.nih.gov
American Women: Assessing Risk Epidemiologically (AWARE - RFA)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$9,079,530August 18, 2022July 31, 2028SCHNALL, REBECCAreporter.nih.gov
HEALthy Brain and Child Development Study at UAB and UANIHNational Institute on Drug Abuse2021 to 2025$9,071,052September 30, 2021June 30, 2026NEWSOM, CASSANDRA R.reporter.nih.gov
Safety/Toxicology, ADME and CMC Activities to Support the Assessment of the mGlu2 PAM SBP-9330 in a Phase 2 Clinical Study in SmokersNIHNational Institute on Drug Abuse2023 to 2025$9,048,057September 30, 2023August 31, 2026COSFORD, NICHOLAS DAVIDreporter.nih.gov
Prevention Research Center: Parenting Among Women Who Are Opioid UsersNIHNational Institute on Drug Abuse2021 to 2023$8,972,150August 15, 2019May 31, 2025LEVE, LESLIE DIANEreporter.nih.gov
Molecular and Circuit Pathogenesis of Alcohol Use DisordersNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$8,884,347December 1, 1997November 30, 2027KASH, THOMAS L.reporter.nih.gov
Center for Genetic Studies of Drug Abuse in Outbred RatsNIHNational Institute on Drug Abuse2021 to 2023$8,856,132June 15, 2014April 30, 2025PALMER, ABRAHAM Areporter.nih.gov
23/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$8,838,592September 30, 2021June 30, 2026ROGERS, CYNTHIA ELISEreporter.nih.gov
7/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT YALENIHNational Institute on Drug Abuse2021 to 2025$8,739,227September 30, 2015March 31, 2027BASKIN-SOMMERS, ARIELLE RYANreporter.nih.gov
Health Economics of Substance Use Disorder, HCV, and HIV Treatment: Supporting Financial Sustainability, Advanced Methods, and Knowledge TranslationNIHNational Institute on Drug Abuse2021 to 2025$8,690,640July 15, 2015April 30, 2030SCHACKMAN, BRUCE Rreporter.nih.gov
Development of PPL-138, a Novel Mixed NOP/Mu Partial Agonist for Treatment of CocaineUse DisorderNIHNational Institute on Drug Abuse2022 to 2024$8,683,509September 30, 2022July 31, 2025TOLL, LAWRENCE Rreporter.nih.gov
Tools for gene editing in marmosetsNIHNational Institute on Drug Abuse2022 to 2025$8,672,011September 1, 2022June 30, 2027WANG, XIAOQINreporter.nih.gov
19/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UVMNIHNational Institute on Drug Abuse2021 to 2025$8,669,646April 15, 2020March 31, 2027GARAVAN, HUGH P.reporter.nih.gov
TCN PATHS Supplemental fundingNIHNational Institute on Drug Abuse2021 to 2024$8,572,442July 15, 2019April 30, 2026WANG, EMILY AI-HUAreporter.nih.gov
Microbiome, Metabolites, and Alcohol in HIV to Reduce CVD (META HIV CVD)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$8,561,222September 10, 2021August 31, 2026FREIBERG, MATTHEW Sreporter.nih.gov
MUSC Specialized Center of Research Excellence on Sex Differences Renewal 2022NIHNational Institute on Drug Abuse2021 to 2025$8,499,200September 1, 2002July 31, 2028MCRAE-CLARK, AIMEE Lreporter.nih.gov
Use of a GLP-1 Agonist to Treat Opioid Use Disorder in Rats and ManNIHNational Institute on Drug Abuse2024 to 2025$8,480,887September 30, 2019April 30, 2027GRIGSON, PATRICIA SUEreporter.nih.gov
International Epidemiology Databases to EvaluateAIDS (IeDEA) Renewal 4NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$8,392,710July 1, 2006July 2, 2026JAQUET, ANTOINEreporter.nih.gov
Rocky Mountain Cannabis Research CenterNIHNational Institute on Drug Abuse2023 to 2025$8,380,548September 1, 2023June 30, 2028HUTCHISON, KENT E.reporter.nih.gov
Yale-SCORE on Sex Differences in Alcohol Use DisorderNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$8,308,091March 10, 2020August 31, 2030MCKEE, SHERRY ANNreporter.nih.gov
3/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MINNESOTANIHNational Institute on Drug Abuse2021 to 2025$8,298,588September 30, 2015March 31, 2027LUCIANA, MONICAreporter.nih.gov
6/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT OHSUNIHNational Institute on Drug Abuse2021 to 2025$8,270,799September 30, 2015March 31, 2027NAGEL, BONNIE J.reporter.nih.gov
Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trialsNIHNational Institute on Drug Abuse2022$8,267,350September 30, 2022September 29, 2025PRAVETONI, MARCOreporter.nih.gov
Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey modelNIHNational Institute on Drug Abuse2021 to 2025$8,243,787August 15, 2021June 30, 2027FOX, HOWARD Sreporter.nih.gov
Development of a Long-acting Enzyme Therapy for Treatment of Cocaine AbuseNIHNational Institute on Drug Abuse2021 to 2022$8,242,506August 15, 2020April 30, 2026ZHAN, CHANG-GUOreporter.nih.gov
Combining Pregabalin with Lofexidine: Can it Increase the Success of Transition to Naltrexone?NIHNational Institute on Drug Abuse2023 to 2025$8,178,365September 30, 2019August 31, 2026KAMPMAN, KYLE MATTHEWreporter.nih.gov
14/21 ABCD-USA Consortium: Research Project Site at CU BoulderNIHNational Institute on Drug Abuse2021 to 2025$8,148,103April 15, 2020March 31, 2027BANICH, MARIE Treporter.nih.gov
Therapeutic Agent for Rapid Reversal of Methamphetamine IntoxicationNIHNational Institute on Drug Abuse2021 to 2022$8,123,947September 30, 2020May 31, 2024LI, XINHUAreporter.nih.gov
LSUHSC-NO Comprehensive Alcohol-HIV/AIDS Research Center (CARC)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$8,052,951December 1, 1996August 31, 2030MOLINA, PATRICIA E.reporter.nih.gov
CHARTER Plus: A resource for cutting-edge research on neurological function and mental health in people with HIV and substance use disorders across the lifespanNIHNational Institute of Mental Health2022 to 2025$7,973,681February 1, 2022November 30, 2026LETENDRE, SCOTT Lreporter.nih.gov
14/24 The Healthy Brain & Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,959,706September 30, 2021June 30, 2027BANDOLI, GRETCHEN E.reporter.nih.gov
Using Implementation Interventions and Peer Recovery Support to Improve Opioid Treatment Outcomes in Community SupervisionNIHNational Institute on Drug Abuse2021 to 2024$7,947,350August 1, 2019April 30, 2025MARTIN, ROSEMARIE Areporter.nih.gov
Development of SBS-226, a MOR agonist / DOR antagonist, for OUDNIHNational Institute on Drug Abuse2024 to 2025$7,941,988September 30, 2024August 31, 2027REICH, JEFFREYreporter.nih.gov
20/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT VCUNIHNational Institute on Drug Abuse2021 to 2025$7,897,207April 15, 2020March 31, 2027BJORK, JAMES Mreporter.nih.gov
4/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,886,572September 30, 2021June 30, 2026KABLE, JULIE Areporter.nih.gov
Development of the novel mu-opioid receptor antagonist methocinnamox (MCAM) for preventing relapse and overdoseNIHNational Institute on Drug Abuse2024 to 2025$7,874,666August 15, 2024December 31, 2027FRANCE, CHARLES Preporter.nih.gov
2/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,856,113September 30, 2021June 30, 2026LEVITT, PATreporter.nih.gov
16/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,814,498September 30, 2021June 30, 2026FOX, NATHAN Areporter.nih.gov
Greater Southern California Node of the Clinical Trials NetworkNIHNational Institute on Drug Abuse2021 to 2025$7,788,993June 1, 2019February 29, 2032MOONEY, LARISSA JEANETTEreporter.nih.gov
3/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,734,571September 30, 2021June 30, 2026HUANG, HAOreporter.nih.gov
Clinical development of an mGlu2 positive allosteric modulator to treat nicotine addictionNIHNational Institute on Drug Abuse2021 to 2022$7,715,052August 15, 2020July 31, 2025COSFORD, NICHOLAS DAVIDreporter.nih.gov
Long-acting naltrexone for pre-release prisoners: A randomized trial of mobile treatmentNIHNational Institute on Drug Abuse2021 to 2023$7,640,612May 1, 2023April 30, 2026GORDON, MICHAEL SCOTTreporter.nih.gov
Reducing Opioid Mortality in Illinois (ROMI)NIHNational Institute on Drug Abuse2021 to 2023$7,594,077July 15, 2019April 30, 2025POLLACK, HAROLD ALEXANDERreporter.nih.gov
8/24 The Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,554,291September 30, 2021June 30, 2026THOMASON, MORIAH Ereporter.nih.gov
Health Systems Node of the NIDA Clinical Trials Network (CTN Project: CTN-141 Hlth Ins Instability)NIHNational Institute on Drug Abuse2021 to 2025$7,514,766March 1, 2025February 29, 2032CAMPBELL, CYNTHIA Ireporter.nih.gov
The International URBAN Alcohol Research Collaboration on HIV/AIDS (ARCH) CenterNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$7,511,308September 10, 2021August 31, 2027SAMET, JEFFREY H.reporter.nih.gov
Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primatesNIHNational Institute on Drug Abuse2023 to 2025$7,434,979June 1, 2023February 29, 2028RANA, TARIQ Mreporter.nih.gov
Boston Alcohol Research Collaboration on HIV/AIDS - Comorbidity Center (Boston ARCH CC)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$7,406,307September 22, 2021August 31, 2027STEIN, MICHAEL Dreporter.nih.gov
Efficacy, safety, and pharmacokinetic study of BICX104 naltrexone subcutaneous implant alone and in combination with bupropion for the treatment of Methamphetamine Use Disorder (MUD).NIHNational Institute on Drug Abuse2024 to 2025$7,405,564March 1, 2024November 30, 2027DEVARNEY, KATHERINE BEEBEreporter.nih.gov
12/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,401,896September 30, 2021June 30, 2026SULLIVAN, ELINOR L.reporter.nih.gov
Cohort Studies of HIV/AIDS and Substance Use in MiamiNIHNational Institute on Drug Abuse2025$7,372,834September 30, 2025June 30, 2030BAUM, MARIANNA Kreporter.nih.gov
Western States Node of the National Drug Abuse Treatment Clinical Trials Network (CTN-139)NIHNational Institute on Drug Abuse2021 to 2025$7,354,769March 1, 2025March 1, 2032KORTHUIS, PHILIP TODDreporter.nih.gov
NIH-DOD-VA Pain Management Collaboratory Coordinating CenterNIHNational Center for Complementary & Integrative Health2021 to 2025$7,344,466September 20, 2017July 31, 2030BECKER, WILLIAM Creporter.nih.gov
20/24 The Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,216,008September 30, 2021June 30, 2026POTTER, ALEXANDRA Sreporter.nih.gov
9/24- Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,202,561September 30, 2021June 30, 2026WAKSCHLAG, LAUREN Sreporter.nih.gov
18/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$7,202,314September 30, 2021June 30, 2026BAKHIREVA, LUDMILA NICOLEreporter.nih.gov
MSM and Substances Cohort at UCLA Linking Infections Noting Effects (MASCULINE)NIHNational Institute on Drug Abuse2021 to 2024$7,177,379September 30, 2013April 30, 2026GORBACH, PAMINA MAEreporter.nih.gov
Improving quality measurement for opioid use disorder treatment using a multi-state Medicaid research networkNIHNational Institute on Drug Abuse2023 to 2025$7,124,763September 30, 2023August 31, 2028DONOHUE, JULIE MARIEreporter.nih.gov
NeMO Archive: SCORCH Support, Coordination and OutreachNIHNational Institute on Drug Abuse2021 to 2025$7,111,105August 1, 2020June 30, 2030WHITE, OWEN Rreporter.nih.gov
Elucidating single cell changes in neurogenic brain regions during HIV and cannabinoid exposureNIHNational Institute on Drug Abuse2023 to 2025$7,084,951May 15, 2023March 31, 2028NDHLOVU, LISHOMWA Creporter.nih.gov
Alcohol Research Consortium in HIV: Ending the HIV Epidemic through interventions and Epidemiology at the intersection of the alcohol and HIV care ContinuaNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$7,057,359September 10, 2021August 31, 2027MCCAUL, MARY Ereporter.nih.gov
Enhanced Cohort methods for HIV Research and Epidemiology (ENCORE) in the United StatesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$7,056,913August 9, 2022December 31, 2027COONEY, ERIN EILEENreporter.nih.gov
A comprehensive dissection of cell types, circuits and molecular adaptations during opioid useNIHNational Institute on Drug Abuse2021 to 2025$7,041,006June 1, 2021March 31, 2027SCHERRER, GREGORYreporter.nih.gov
17/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$6,995,393September 30, 2021June 30, 2026WILSON, SYLIAreporter.nih.gov
1/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$6,945,966September 30, 2021June 30, 2026GAO, WEIreporter.nih.gov
PharmGKBNIHNational Human Genome Research Institute2021 to 2025$6,940,000April 3, 2020December 31, 2026KLEIN, TERI ELLENreporter.nih.gov
Impact of Cannabinoid Across the Lifespan (ICAL)NIHNational Institute on Drug Abuse2021 to 2025$6,925,926July 1, 2018April 30, 2029PIOMELLI, DANIELEreporter.nih.gov
Development of sigma receptor/DAT dual-targeting compounds to treat stimulant use disorderNIHNational Institute on Drug Abuse2023 to 2024$6,903,733August 15, 2023July 31, 2026REICH, JEFFREYreporter.nih.gov
Person-centered quality measurement and management in a system for addictions treatment in New York StateNIHNational Institute on Drug Abuse2023 to 2025$6,873,344September 30, 2023August 31, 2028NEIGHBORS, CHARLES Jreporter.nih.gov
Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Markets and Drug TourismNIHNational Institute on Drug Abuse2021 to 2024$6,868,774April 1, 2020January 31, 2026STRATHDEE, STEFFANIE A.reporter.nih.gov
Duke HEAL R-DECNIHOffice of the Director, National Institutes of Health2022 to 2023$6,823,028September 23, 2022June 30, 2025HORNIK, CHRISTOPHreporter.nih.gov
18/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT THE UNIVERSITY OF FLORIDANIHNational Institute on Drug Abuse2021 to 2025$6,741,640April 15, 2020March 31, 2027NIXON, SARA JOreporter.nih.gov
12/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U PITTSBURGHNIHNational Institute on Drug Abuse2021 to 2025$6,727,386September 30, 2015March 31, 2027CLARK, DUNCAN B.reporter.nih.gov
Implementing and Personalizing Best-In-Class Opioid-sparing Pain Management for Major Inpatient Surgeries in ChildrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$6,720,269September 5, 2024August 31, 2029SADHASIVAM, SENTHILKUMARreporter.nih.gov
An Intranasal GDNF Gene Therapy for Opioid Relapse ReductionNIHNational Institute on Drug Abuse2021$6,693,512September 15, 2021August 31, 2025WASZCZAK, BARBARA LEEreporter.nih.gov
PDE7 Inhibitor for the Treatment of Cocaine Use DisorderNIHNational Institute on Drug Abuse2023 to 2025$6,689,019April 15, 2023March 31, 2027GAITANARIS, GEORGEreporter.nih.gov
Development of cebranopadol, a potent dual MOP/NOP agonist, for the treatment of Opioid Use Disorder (OUD)NIHNational Institute on Drug Abuse2023 to 2024$6,654,182August 15, 2023July 31, 2025GRIECO, JOSEPHreporter.nih.gov
21/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$6,644,967September 30, 2021June 30, 2026DEAN III, DOUGLAS CARLreporter.nih.gov
10/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT SRINIHNational Institute on Drug Abuse2021 to 2025$6,613,511September 30, 2015March 31, 2027BAKER, FIONA Creporter.nih.gov
22/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2022 to 2025$6,605,848July 20, 2022June 30, 2026HOWELL, BRITTANY ROLLINSreporter.nih.gov
13/24 The Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$6,574,535September 30, 2021June 30, 2026PEREZ-EDGAR, KORALY Ereporter.nih.gov
HEAL Data2Action Modeling and Economic Resource CenterNIHNational Institute on Drug Abuse2022 to 2025$6,550,146September 30, 2022August 31, 2027SCHACKMAN, BRUCE Rreporter.nih.gov
Novel therapy for alcoholic liver disease-associated hepatorenal syndromeNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$6,485,223September 25, 2021August 31, 2027SUBRAMANIAN, MANIreporter.nih.gov
Whole Person Reference Physiome Research and Coordination CenterNIHNational Center for Complementary & Integrative Health2025$6,476,031August 8, 2025July 31, 2028SNYDER, MICHAEL P.reporter.nih.gov
17/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UCLANIHNational Institute on Drug Abuse2021 to 2025$6,450,915April 15, 2020March 31, 2027DAPRETTO, MIRELLAreporter.nih.gov
Characterization, optimization, and development of dual mGlu2/3 positive allosteric modulators for opioid use disorderNIHNational Institute on Drug Abuse2022$6,445,203July 15, 2022June 30, 2025COSFORD, NICHOLAS DAVIDreporter.nih.gov
Impact of maternal substance use on offspring neurobehavioral developmentNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023$6,439,263September 1, 2023August 31, 2026EDLOW, ANDREA GOLDBERGreporter.nih.gov
Evaluation of psilocybin as an adjunctive treatment for opioid use disorder in methadone-maintained patients who continue to use illicit opioidsNIHNational Institute on Drug Abuse2024 to 2025$6,417,488September 30, 2024August 31, 2026BOGENSCHUTZ, MICHAEL PARKSreporter.nih.gov
Development of SBI-553, an allosteric modulator of NTR1, for the treatment of substance use disordersNIHNational Institute on Drug Abuse2023 to 2024$6,363,247September 30, 2019August 31, 2025JACKSON, MICHAELreporter.nih.gov
Southeast Enrollment Center Consortium 2 (SEEC-2)NIHOffice of the Director, National Institutes of Health2024 to 2025$6,360,000July 1, 2024June 30, 2026ZUCHNER, STEPHANreporter.nih.gov
Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease PainNIHNational Center for Complementary & Integrative Health2021 to 2024$6,352,490September 21, 2020August 31, 2025DOORENBOS, ARDITH Zreporter.nih.gov
Naltrexone Transdermal Patch - An Accessible, Patient-Focused Option to Treat OUD RelapseNIHNational Institute on Drug Abuse2022 to 2023$6,351,015September 30, 2022August 31, 2025GARDINER, ANDREWreporter.nih.gov
The HIV and Alcohol Research center focused on Polypharmacy (HARP)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$6,323,238September 10, 2021August 31, 2026JUSTICE, AMY CAROLINEreporter.nih.gov
AACAP Physician Scientist Program in Substance UseNIHNational Institute on Drug Abuse2021 to 2025$6,304,811January 1, 1998May 31, 2026GRAY, KEVIN M.reporter.nih.gov
Development of an implantable closed-loop system for delivery of naloxone for the prevention of opioid-related overdose deathsNIHNational Institute on Drug Abuse2021$6,275,050September 30, 2019August 31, 2025GEREAU, ROBERT Wreporter.nih.gov
Single Cell Transcriptomics of the Cocaine Use Disorder in the Context of HIVNIHNational Institute on Drug Abuse2022 to 2025$6,266,450June 15, 2022March 31, 2027CHENG, CHRISTINEreporter.nih.gov
Medication Development for the Treatment of Alcohol Use DisorderNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$6,237,752December 20, 2024August 31, 2025BERGESON, SUSAN E.reporter.nih.gov
Southwest Clinical Trials Node: Clinical Research and Practice to Address Substance Use in Diverse, Rural, and Underserved PopulationsNIHNational Institute on Drug Abuse2021 to 2025$6,192,905June 1, 2019February 29, 2032PAGE, KIMBERLYreporter.nih.gov
Neuronal mechanisms of human episodic memoryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$6,162,146September 30, 2020July 31, 2025RUTISHAUSER, UELIreporter.nih.gov
Development of a Longitudinal Observational Research Registry for the Study of Medicinal Cannabis Use and HealthNIHNational Institute on Drug Abuse2023 to 2025$6,116,522June 1, 2023April 30, 2028VANDREY, RYAN Greporter.nih.gov
A Therapeutic Agent to Lower the Level of Synthetic Opioids in the BodyNIHNational Institute on Drug Abuse2023 to 2024$6,087,655September 1, 2023August 31, 2025LI, XINHUAreporter.nih.gov
10/24 Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2025$6,021,397September 30, 2021June 30, 2026CROFF, JULIE MAYreporter.nih.gov
MIRHIQL Resource Center for Improving Quality of Life with Chronic Pain (MRC)NIHNational Institute on Drug Abuse2023$5,978,096August 15, 2023July 31, 2028ADAMS, MEREDITH C. B.reporter.nih.gov
CB1 Neutral Antagonists for Alcohol Use DisorderNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$5,965,782September 20, 2020August 31, 2025MAKRIYANNIS, ALEXANDROSreporter.nih.gov
Johns Hopkins HIV Clinical CohortNIHNational Institute on Drug Abuse2021 to 2024$5,955,256July 1, 2014March 31, 2026MOORE, RICHARD DOUGLASreporter.nih.gov
Justice Community Opioid Innovation Network (JCOIN): TCU Clinical Research CenterNIHNational Institute on Drug Abuse2021 to 2023$5,941,436July 15, 2019April 30, 2025KNIGHT, KEVINreporter.nih.gov
11/21 ABCD-USA Consortium: Research Project Site at UWMNIHNational Institute on Drug Abuse2021 to 2025$5,941,105July 15, 2017March 31, 2027LISDAHL, KRISTA MAURINEreporter.nih.gov
Penn PET Addiction Center of Excellence (PACE)NIHNational Institute on Drug Abuse2021 to 2023$5,914,143August 15, 2019June 30, 2025MACH, ROBERT Hreporter.nih.gov
Defining the impact of drug use on immune function and fitness against HIV-1NIHNational Institute on Drug Abuse2021 to 2025$5,880,000May 1, 2021April 30, 2026SHALEK, ALEX Kreporter.nih.gov
Optimizing HIV prevention for high-risk methamphetamine-using men who have sex with menNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$5,855,396April 8, 2022April 30, 2027GROV, CHRISTIANreporter.nih.gov
Non-Invasive Vagal Nerve Stimulation in Patients with Opioid Use DisordersNIHNational Institute on Drug Abuse2023 to 2025$5,776,792August 15, 2020April 30, 2027BREMNER, JAMES DOUGLASreporter.nih.gov
Columbia University Science of Behavior Change Resource and Coordinating Center renewalNIHNational Institute on Aging2021 to 2024$5,758,737September 30, 2015August 31, 2025EDMONDSON, DONALDreporter.nih.gov
13/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT MUSCNIHNational Institute on Drug Abuse2021 to 2025$5,745,020July 1, 2017March 31, 2027SQUEGLIA, LINDSAYreporter.nih.gov
Effects of HIV, Cocaine, and Prolonged ART Use on Subclinical Cardiovascular DiseaseNIHNational Institute on Drug Abuse2021 to 2024$5,744,264June 1, 2016April 30, 2025LAI, SHENGHANreporter.nih.gov
Zambia Alabama HIV Alcohol Comorbidities Program (ZAMBAMA)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$5,703,886September 10, 2021August 31, 2026CROPSEY, KAREN Lreporter.nih.gov
Clinical Trials Network: Pacific Northwest Node (CTN-0082, -0131, -0139 and dissemination library)NIHNational Institute on Drug Abuse2021 to 2025$5,664,540March 1, 2025February 29, 2032HATCH, MARY AKIKOreporter.nih.gov
Feasibility of Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use DisorderNIHNational Institute on Drug Abuse2022 to 2024$5,635,650September 30, 2018August 31, 2025REZAI, ALI Rreporter.nih.gov
First-in-Human Clinical Development of a Novel Drug Candidate with a First-in-Class Mechanism for Smoking Cessation and AbstinenceNIHNational Institute on Drug Abuse2021 to 2024$5,613,363August 1, 2021April 30, 2024ZAVERI, NURULAIN Treporter.nih.gov
Meth-OD: A PHASE 2A STUDY OF IXT-M200 IN METHAMPHETAMINE OVERDOSE PATIENTSNIHNational Institute on Drug Abuse2021 to 2022$5,613,312September 30, 2020June 30, 2024STEVENS, MISTY WARDreporter.nih.gov
HEAL Accelerator: Leveraging Partnerships and Targeted Dissemination to Advance UptakeNIHOffice of the Director, National Institutes of Health2022 to 2023$5,606,461September 23, 2022August 31, 2025TAXMAN, FAYE Sreporter.nih.gov
Preclinical Development of Novel Dual OXR/KOR Antagonists for Treatment of Substance Use DisorderNIHNational Institute on Drug Abuse2021$5,598,515September 30, 2021September 29, 2025BUTERA, JOHN Areporter.nih.gov
PF614 MPAR Abuse Deterrent opioid prodrug with overdose protection: Pre-Clinical Development and Phase 1 Clinical TrialNIHNational Institute on Drug Abuse2021 to 2022$5,585,570September 15, 2018December 31, 2023KIRKPATRICK, LYNNreporter.nih.gov
Improving Retention across the OUD Service Cascade upon Re-entry from Jail using Recovery Management CheckupsNIHNational Institute on Drug Abuse2021 to 2023$5,523,458July 15, 2019April 30, 2026DENNIS, MICHAEL L.reporter.nih.gov
JCOIN data curation and archivingNIHNational Institute on Drug Abuse2024 to 2025$5,521,141June 15, 2019May 31, 2029SCHNEIDER, JOHNreporter.nih.gov
A Genetic Engineering Toolbox for Marmosets (GETMarm): Development and optimization of genome editing and assisted reproduction techniques for marmoset modelsNIHNational Institute on Drug Abuse2021 to 2025$5,517,113August 1, 2021May 31, 2026FENG, GUOPINGreporter.nih.gov
Reducing Disparities in Dementia and VCID Outcomes in a Multicultural Rural PopulationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$5,484,212March 6, 2020March 21, 2025GALVIN, JAMES Ereporter.nih.gov
Facilitating Opioid Care Connections: System level strategies to improve use of MAT and movement through the opioid care cascade for defendants in a new Opioid Court systemNIHNational Institute on Drug Abuse2021 to 2023$5,473,502July 15, 2019April 30, 2026ELKINGTON, KATHERINE Sreporter.nih.gov
16/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UNIVERSITY OF ROCHESTERNIHNational Institute on Drug Abuse2021 to 2025$5,419,981April 15, 2020March 31, 2027FOXE, JOHN Jreporter.nih.gov
Great Lakes & Mid-Atlantic Node (GLMN) of the NIDA CTN (CTN-0144)NIHNational Institute on Drug Abuse2022 to 2025$5,408,561March 1, 2025February 29, 2032KARNIK, NIRANJAN SUBHASHreporter.nih.gov
CVL-354, a kappa opioid receptor antagonist for treatment of opioid use disorder, withdrawal and relapseNIHNational Institute on Drug Abuse2021$5,400,000September 30, 2021May 31, 2023IREDALE, PHILIPreporter.nih.gov
CVL-354, a kappa opioid receptor antagonist for treatment of opioid use disorder, withdrawal and relapseNIHNational Institute on Drug Abuse2023 to 2024$5,400,000September 30, 2021May 20, 2025SUIDAN, GEORGETTEreporter.nih.gov
Development of Lofexidine as a First-line Non-Opioid Pharmacologic Treatment for Neonatal Opioid Withdrawal SyndromeNIHNational Institute on Drug Abuse2021$5,353,314September 30, 2021August 31, 2025GULLO, KRISTEN LEANNreporter.nih.gov
Development of a Potent and Selective Nav1.8 inhibitor for the Treatment of Acute and Chronic Pain with the Goal of Reducing Opioid Use and Preventing Opioid Use DisordersNIHNational Institute on Drug Abuse2023$5,341,667May 15, 2023April 30, 2025HUNTER, JOHN CURETONreporter.nih.gov
GATHER: Growing a Tribal Healing Effort through ResearchNIHNational Institute on Drug Abuse2024 to 2025$5,340,103August 1, 2024July 31, 2026PARKER, MYRA ELIZABETHreporter.nih.gov
Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSNIHNational Institute on Drug Abuse2021 to 2024$5,321,290March 1, 2015April 30, 2026HAYASHI, KANNAreporter.nih.gov
TMP-301, A Negative Allosteric Modulator of type 5 metabotropic glutamate receptors (mGluR5), for Treatment of Cocaine Use DisorderNIHNational Institute on Drug Abuse2022 to 2023$5,310,920September 1, 2022August 31, 2025MEYERS, CHARLES DANIELreporter.nih.gov
SOAR: Smartphones for Opioid Addiction RecoveryNIHNational Institute on Drug Abuse2021 to 2025$5,292,761August 15, 2021May 31, 2027GLIMCHER, PAUL Wreporter.nih.gov
Optimization and testing of anti-methamphetamine antibody therapy to support pivotal clinical trials and commercializationNIHNational Institute on Drug Abuse2021 to 2022$5,281,643May 1, 2020February 29, 2024STEVENS, MISTY WARDreporter.nih.gov
Kentucky Women's Justice Community Opioid Innovation Network (WJCOIN)NIHNational Institute on Drug Abuse2021 to 2023$5,280,405July 15, 2019April 30, 2026STATON, MICHELEreporter.nih.gov
A novel and highly selective orexin 1 receptor antagonist for the treatment of patients with opioid use disorder.NIHNational Institute on Drug Abuse2021 to 2022$5,265,428August 15, 2021March 31, 2024GURRELL, IANreporter.nih.gov
Reducing variation in access to medications for opioid use disorder in MedicaidNIHNational Institute on Drug Abuse2022 to 2025$5,252,187September 1, 2022July 31, 2026DONOHUE, JULIE MARIEreporter.nih.gov
High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,225,127January 1, 2025April 30, 2025MCLAUGHLIN, BRYAN Lreporter.nih.gov
#4Corners4Health: A Social Media Cancer Prevention Program for Rural Emerging AdultsNIHNational Cancer Institute2022 to 2025$5,181,703September 8, 2022August 31, 2027BULLER, DAVID Breporter.nih.gov
Development of TNX-1300 (Double Mutant Cocaine Esterase) for the Treatment of Life-Threatening Cocaine IntoxicationNIHNational Institute on Drug Abuse2022 to 2025$5,181,674August 1, 2022November 30, 2025SULLIVAN, GREGORY Mreporter.nih.gov
Understanding Sensorimotor Control Through Realistic Neuro-Biomechanical SimulationNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$5,163,869September 5, 2024August 31, 2027OLVECZKY, BENCE Preporter.nih.gov
Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodologyNIHNational Institute of Mental Health2024 to 2025$5,154,254August 9, 2024May 31, 2028WILCOX, HOLLY Creporter.nih.gov
Addressing alcohol misuse in HIV prevention and care: The Brown University Alcohol Research Center on HIV (ARCH)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$5,146,588September 30, 2010May 31, 2026KAHLER, CHRISTOPHER W.reporter.nih.gov
Nezavist a Novel Molecule for Treatment of Alcohol Use DisorderNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$5,128,513September 25, 2015June 30, 2027TABAKOFF, BORISreporter.nih.gov
Appalachian NodeNIHNational Institute on Drug Abuse2021 to 2025$5,126,241June 15, 2019February 29, 2032LIEBSCHUTZ, JANE M.reporter.nih.gov
HEAL Research on Interventions for Stability and Engagement (RISE) Network Coordination CenterNIHNational Institute on Drug Abuse2024 to 2025$5,088,719September 30, 2022June 30, 2027CANCE, JESSICA DUNCANreporter.nih.gov
Fentalog II: Medical Consequences of Novel Fentanyl Analog Overdose Using the Toxicology Investigators Consortium (TOXIC)NIHNational Institute on Drug Abuse2021 to 2025$5,080,519April 1, 2020March 31, 2030MANINI, ALEX FRANCISreporter.nih.gov
NIDA CENTER FOR GENETIC STUDIES. MARCH 14, 2022 - MARCH 13, 2023. N01DA-18-7797. TASK ORDER 75N95022F00001 (TO8).NIHNational Institute on Drug Abuse2021 to 2022$5,000,000March 14, 2022March 13, 2023TISCHFIELD, JAYreporter.nih.gov
Effects of mu-opiate receptor engagement on microbial translocation and residual immune activation in HIV-infected, ART suppressed opioid use disorder patents initiating medication-assisted treatmentNIHNational Institute on Drug Abuse2021 to 2023$4,952,252August 1, 2019June 30, 2025MONTANER, LUIS Jreporter.nih.gov
HEAL Initiative: Research to Foster an Opioid Use Disorder Treatment System Patients Can Count OnNIHNational Institute on Drug Abuse2023 to 2025$4,935,947September 30, 2023August 31, 2028MARK, TAMI Lreporter.nih.gov
Injectable naltrexone 2-month depot formulationsNIHNational Institute on Drug Abuse2022 to 2024$4,908,655April 1, 2019December 31, 2025PARK, KINAMreporter.nih.gov
Nonpharmacologic Pain Management in FQHC primary care clinicsNIHNational Institute of Nursing Research2021 to 2024$4,905,424September 25, 2020August 31, 2026FRITZ, JULIE Mreporter.nih.gov
Modeling drugs of abuse-HIV interactions using iPSC-derived human cerebral organoidsNIHNational Institute on Drug Abuse2021 to 2025$4,890,555September 30, 2021July 31, 2026SANNA, PIETRO Preporter.nih.gov
Toward comprehensive models of naturalistic cooperation and competition in primatesNIHNational Institute on Drug Abuse2025$4,888,497September 1, 2025June 30, 2030CHANG, STEVE W. C.reporter.nih.gov
Rapid Actionable Data for Opioid Response in Kentucky (RADOR-KY)NIHNational Institute on Drug Abuse2022 to 2025$4,881,729September 30, 2022August 31, 2027SLAVOVA, SVETLA STEFANOVAreporter.nih.gov
Ending HIV: Bringing Integrated Prevention and Treatment Services to People Who Use Drugs Where They LiveNIHNational Institute on Drug Abuse2022 to 2025$4,857,421June 15, 2022May 31, 2027SPRINGER, SANDRA ANNreporter.nih.gov
Massachusetts Justice Community Opioid Innovation Network (JCOIN) Clinical Research CenterNIHNational Institute on Drug Abuse2021 to 2023$4,788,260July 15, 2019April 3, 2025FRIEDMANN, PETER Dreporter.nih.gov
Integrating Nonpharmacologic Strategies for Pain with Inclusion, Respect, and Equity (INSPIRE): Tailored digital tools, telehealth coaching, and primary care coordinationNIHNational Institute of Neurological Disorders and Stroke2024$4,783,072August 15, 2022July 31, 2027SATTERFIELD, JASON Mreporter.nih.gov
Sorting and Sequencing Latent Reservoirs in HIV+ Opioid UsersNIHNational Institute on Drug Abuse2023 to 2025$4,748,827September 15, 2023July 31, 2028OTT, MELANIE MARIAreporter.nih.gov
NCANDA: Data Analysis ResourceNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$4,747,934September 15, 2012June 30, 2027POHL, KILIAN MARIAreporter.nih.gov
Single Chromatin Fiber Sequencing and Longitudinal Epigenomic Profiling in HIV+ Brain Cells Exposed to Narcotic and StimulantNIHNational Institute on Drug Abuse2022 to 2025$4,732,000April 1, 2022February 28, 2027AKBARIAN, SCHAHRAMreporter.nih.gov
ABCD-USA Consortium: Data Analysis, Informatics and Resource CenterNIHNational Institute on Drug Abuse2025$4,713,123September 30, 2015March 31, 2026DALE, ANDERS Mreporter.nih.gov
MEB-1170: A New Chemical Entity for the Treatment of Opioid Use DisorderNIHNational Institute on Drug Abuse2025$4,710,576July 1, 2025June 30, 2027KUO, LAWRENCE Creporter.nih.gov
Integrating Addiction and Infectious Diseases Services into Primary Care in Rural SettingsNIHNational Institute on Drug Abuse2021 to 2025$4,664,222August 1, 2021May 31, 2027ALTICE, FREDERICK LEWISreporter.nih.gov
Single nucleus gene expression in moderate and compulsive drug self-administration in a rodent model of HIVNIHNational Institute on Drug Abuse2022 to 2025$4,653,858March 15, 2022November 30, 2026SANNA, PIETRO Preporter.nih.gov
Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy - Yale Resource Center (MIRHIQL-YRC)NIHNational Institute on Drug Abuse2023$4,626,338August 15, 2023July 31, 2026BECKER, WILLIAM Creporter.nih.gov
Development of a Soluble Epoxide Hydrolase Inhibitor to Spare or Replace Opioid AnalgesicsNIHNational Institute on Drug Abuse2024 to 2025$4,623,799September 30, 2019December 31, 2026CORTES-PUCH, IRENEreporter.nih.gov
IMPETUS: Integrated Mechanisms, Phenotypes, and Translational Underpinnings of Chronic Pain after SurgeryNIHNational Institute of Neurological Disorders and Stroke2024$4,618,885September 18, 2024August 31, 2027HAROUTOUNIAN, SIMONreporter.nih.gov
HEALing Measurement Center: Enhancing Opioid Use Disorder Recovery through Measurement Based CareNIHNational Institute on Drug Abuse2023 to 2025$4,598,946September 30, 2023August 31, 2028CLOUTIER, RENEE Mreporter.nih.gov
Building Social and Structural Connections for the Prevention of OUD among Youth Experiencing Homelessness: An RCT Examining Biopsychosocial MechanismsNIHNational Institute on Drug Abuse2023 to 2025$4,538,190September 30, 2023July 31, 2028FORD, JODI L.reporter.nih.gov
Optimizing HIV prevention for highly vulnerable methamphetamine-using sexual minority menNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$4,518,889April 8, 2022April 30, 2024GROV, CHRISTIANreporter.nih.gov
A Long-Acting Bioabsorbable Naltrexone Subcutaneous Implant for Opioid Use DisorderNIHNational Institute on Drug Abuse2024 to 2025$4,514,823April 1, 2019April 30, 2027COHEN, STEVEN Mreporter.nih.gov
National Drug Early Warning System Coordinating Center (NDEWS)NIHNational Institute on Drug Abuse2021 to 2025$4,490,739April 1, 2020February 28, 2030COTTLER, LINDA B.reporter.nih.gov
Substance Use Among American Indian Youth: Epidemiology and EtiologyNIHNational Institute on Drug Abuse2021 to 2025$4,488,064September 1, 1983April 30, 2030CRABTREE, MEGHAN Areporter.nih.gov
Advancement of AEF0117 as a potential treatment for Cannabis Use Disorder: Preclinical toxicity and Clinical pharmacokinetic studiesNIHNational Institute on Drug Abuse2021 to 2023$4,483,517September 15, 2021July 31, 2025LEVIN, FRANCES RUDNICKreporter.nih.gov
Opioid use disorders: UF Pharmacy medications discovery and developmentNIHNational Institute on Drug Abuse2021 to 2023$4,479,677December 15, 2018November 30, 2024MCCURDY, CHRISTOPHER Rreporter.nih.gov
Promoting Community Wellbeing Through Indigenous Science and HealingNIHNational Institute on Drug Abuse2024 to 2025$4,470,789August 15, 2024July 31, 2026MCDONELL, MICHAEL Greporter.nih.gov
Alcohol Policy Information System (APIS)NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$4,431,277January 1, 2023December 31, 2025SPARKS, ALICIAreporter.nih.gov
Non-pharmacological Options in postoperative Hospital-based And Rehabilitation pain Management (NOHARM) pragmatic clinical trialNIHNational Institute on Aging2021 to 2023$4,429,006September 30, 2019August 31, 2025CHEVILLE, ANDREA LYNNEreporter.nih.gov
Leveraging the National Cancer Institute’s Cancer Center Cessation Initiative (C3I) Program to Evaluate and Transform Smoking Cessation Treatment in Cancer CareNIHNational Cancer Institute2021 to 2025$4,423,867August 1, 2015August 31, 2029FIORE, MICHAEL Creporter.nih.gov
Discovery of Addiction-Related Genes with Advanced Mouse ResourcesNIHNational Institute on Drug Abuse2021 to 2025$4,405,786April 1, 2015May 31, 2027CHESLER, ELISSA Jreporter.nih.gov
Impact of a novel HIV peer navigationand overdose prevention intervention on engagement in the HIV prevention and treatment cascade.NIHNational Institute on Drug Abuse2021 to 2025$4,391,293September 1, 2021June 30, 2027SHERMAN, SUSAN G.reporter.nih.gov
A comparative evaluation of overdose prevention programs in New York City and Rhode IslandNIHNational Institute on Drug Abuse2023 to 2025$4,373,618May 1, 2023February 28, 2027CERDA, MAGDALENAreporter.nih.gov
Methocinnamox (MCAM): A novel opioid receptor antagonistNIHNational Institute on Drug Abuse2023$4,373,045July 1, 2023June 30, 2024FRANCE, CHARLES Preporter.nih.gov
Increasing Access to Hepatitis C Treatment in Opioid Endemic Rural Areas: the Kentucky Viral Hepatitis Treatment (KeY Treat) StudyNIHNational Institute on Drug Abuse2021 to 2023$4,371,481September 30, 2018July 31, 2025HAVENS, JENNIFER Rreporter.nih.gov
Multilevel strategies to understand and modify the role of structural and environmental context on HIV inequities for sexual and gender minorities of colorNIHNational Institute of Allergy and Infectious Diseases2022 to 2023$4,361,269March 18, 2022May 3, 2024RENDINA, H. JONATHONreporter.nih.gov
WF DISC: Navigating Data Solutions for Chronic Pain and Opioid Use DisorderNIHNational Institute on Drug Abuse2022 to 2025$4,339,941September 30, 2022August 31, 2028ADAMS, MEREDITH C. B.reporter.nih.gov
Mu Opioid Receptor Modulator Development to Treat Opioid Use DisorderNIHNational Institute on Drug Abuse2023 to 2025$4,337,165September 30, 2019January 31, 2027ZHANG, YANreporter.nih.gov
MR-guided focused ultrasound to eradicate CNS viral reservoirs and promote neurogenesis in the HIV-infected brainNIHNational Institute on Drug Abuse2021 to 2025$4,326,000June 1, 2021April 30, 2027CHANG, LINDAreporter.nih.gov
Translational Studies of Cannabis Administration, Cognition, and the Endocannabinoid System in HIVNIHNational Institute on Drug Abuse2021 to 2025$4,324,439May 1, 2021July 31, 2026MINASSIAN, ARPIreporter.nih.gov
Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brainNIHNational Institute on Drug Abuse2021 to 2025$4,310,228April 1, 2021February 28, 2027AKBARIAN, SCHAHRAMreporter.nih.gov
Tracking HIV Infection & Alcohol Abuse CNS Comorbidity with NeuroimagingNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$4,308,486September 30, 2007August 31, 2028PFEFFERBAUM, ADOLFreporter.nih.gov
Biased Mu-Opioid Receptor Analgesics to Prevent Overdose and Opioid Use DisordersNIHNational Institute on Drug Abuse2021 to 2023$4,306,927September 15, 2018August 31, 2023KUO, LAWRENCE Creporter.nih.gov
Establishment and Characterization of Novel Mutant Mouse Models for the Addiction Research CommunityNIHNational Institute on Drug Abuse2021 to 2025$4,218,988August 15, 2021May 31, 2027KUMAR, VIVEKreporter.nih.gov
Antibody-based therapy for fentanyl-related opioid use disorderNIHNational Institute on Drug Abuse2023$4,202,550September 30, 2023August 31, 2025DESAI, RAJEEV INDRAJITreporter.nih.gov
Neuronal and Network Mechanisms of Electrocortical StimulationNIHNational Institute of Neurological Disorders and Stroke2023$4,175,793August 15, 2023July 31, 2026SLUTZKY, MARC W.reporter.nih.gov
Use of Next-Gen Sequencing to Identify Genetic Variants that Influence compulsive Oxycodone Intake in Outbred RatsNIHNational Institute on Drug Abuse2021 to 2025$4,173,211April 1, 2018February 29, 2028GEORGE, OLIVIERreporter.nih.gov
Promoting HIV risk reduction among people who inject drugs: A stepped care approach using contingency management with PrEP navigationNIHNational Institute on Drug Abuse2021 to 2025$4,159,587July 1, 2020May 31, 2027EDELMAN, E. JENNIFERreporter.nih.gov
Novel Therapeutics for Opioid Use Disorder in the Acute Overdose and Maintenance SettingsNIHNational Institute on Drug Abuse2022 to 2023$4,143,992September 30, 2019August 31, 2025GEHLERT, DONALD Rreporter.nih.gov
Alcohol: A Modifiable Risk Factor for Ataxia and Decline in MCINIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$4,133,560April 1, 1996June 30, 2027SULLIVAN, EDITH VIONIreporter.nih.gov
CNS Deficits: Interaction of Age and AlcoholismNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$4,120,296July 1, 1983April 30, 2027PFEFFERBAUM, ADOLFreporter.nih.gov
Opiod Analgesic Reduction Study (OARS): Managing Acute Post-Operative Surgical PainNIHNational Institute of Dental & Craniofacial Research2022 to 2023$4,090,798August 1, 2020July 31, 2025FELDMAN, CECILEreporter.nih.gov
Using SMART Design to Identify an Effective and Cost-Beneficial Approach to Preventing OUD in Justice-Involved YouthNIHNational Institute on Drug Abuse2021 to 2023$4,080,444September 30, 2019August 31, 2024AHRENS, KYM Rreporter.nih.gov
Development of Next-generation Pharmacotherapy for Opioid Use DisordersNIHNational Institute on Drug Abuse2022 to 2024$4,073,436January 1, 2019July 31, 2025ZAVERI, NURULAIN Treporter.nih.gov
Integrating tobacco use cessation into HIV Care and Treatment in Ministry of Health Facilities in Kisumu County, KenyaNIHNational Cancer Institute2021 to 2025$4,048,603September 16, 2021August 31, 2026BIALOUS, STELLA AGUINAGAreporter.nih.gov
CAMELLIA Cohort: A longitudinal study to understand sexual health and prevention among women in AlabamaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$4,046,847September 8, 2022August 31, 2027RANA, AADIAreporter.nih.gov
Single nucleus gene expression in moderate and compulsive opioid self-administration in a rodent model of HIVNIHNational Institute on Drug Abuse2023 to 2025$4,045,522September 1, 2023June 30, 2028SANNA, PIETRO Preporter.nih.gov
Integrative Single Cell isoform and chromatin accessibility Mapping of Chronic Opioid Exposure in Cognitive Brain Areas in HIVNIHNational Institute on Drug Abuse2021 to 2025$4,038,720September 30, 2021June 30, 2027TILGNER, HAGEN ULRICHreporter.nih.gov
Increasing Peer Support for OUD Recovery through Digital Health: A National Randomized Controlled TrialNIHNational Institute on Drug Abuse2021 to 2025$4,035,370August 15, 2021July 31, 2027BEAUDOIN, FRANCESCAreporter.nih.gov
Health systems innovations for supporting transitions of care for incarcerated people living with substance use disordersNIHNational Institute on Drug Abuse2021 to 2025$4,022,949September 30, 2019April 30, 2029WESTERGAARD, RYAN PATRICKreporter.nih.gov
Impact of chronic alcohol consumption on the functional and epigenetic landscapes of monocytes and their progenitorsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,998,523September 1, 2020August 31, 2029MESSAOUDI, ILHEMreporter.nih.gov
Identification of Genetic Variants that Contribute to Compulsive Cocaine Intakein RatsNIHNational Institute on Drug Abuse2021 to 2025$3,976,898April 1, 2017June 30, 2027GEORGE, OLIVIERreporter.nih.gov
NIDA Epidemiology Training ProgramNIHNational Institute on Drug Abuse2021 to 2025$3,975,550August 1, 1995June 30, 2028MAHER, BRION Sreporter.nih.gov
Early Life Stress, Chronic Drug Use and Neuroplasticity in Nonhuman Primate Models of Cocaine Abuse: Relevance to Treatment StrategiesNIHNational Institute on Drug Abuse2021 to 2025$3,974,079April 1, 2021January 31, 2027SANCHEZ, MAR Mreporter.nih.gov
5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use DisorderNIHNational Institute on Drug Abuse2021 to 2024$3,972,165September 30, 2021June 30, 2026JOHNSON, MATTHEW WAYNEreporter.nih.gov
PWID Opportunities to Improve TrEat and Retain (POINTER)NIHNational Institute on Drug Abuse2022 to 2025$3,963,265September 1, 2020May 31, 2027LUCAS, GREGORY Mreporter.nih.gov
Development of novel therapeutics for opioid dependenceNIHNational Institute on Drug Abuse2021 to 2022$3,944,970September 30, 2018August 31, 2024KENNY, PAUL J.reporter.nih.gov
Researching Effective Strategies to Prevent Opioid Death (RESPOND)NIHNational Institute on Drug Abuse2021 to 2025$3,943,189June 1, 2018July 31, 2028LINAS, BENJAMIN P.reporter.nih.gov
ADHD diagnosis in adulthood: Implications for cannabis use and consequencesNIHNational Institute on Drug Abuse2021 to 2025$3,942,681July 1, 2020May 31, 2030MOLINA, BROOKE S.G.reporter.nih.gov
National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA): San Diego Research Project SiteNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,941,823September 1, 2012June 30, 2027TAPERT, SUSAN F.reporter.nih.gov
Evaluation of Cannabidiol for Reduction of Brain NeuroinflammationNIHNational Institute on Drug Abuse2021 to 2025$3,931,875June 1, 2021March 31, 2027LOGGIA, MARCO LUCIANOreporter.nih.gov
PRODUCTION, ANALYSIS, AND DISTRIBUTION OF CANNABIS AND RELATED MATERIALS. POP: MARCH 23, 2015 - MARCH 22, 2023. N01DA-15-7793.NIHNational Institute on Drug Abuse2021 to 2022$3,928,369March 23, 2015March 22, 2023ELSOHLY, MAHMOUDreporter.nih.gov
Comprehensive, tailored, technology-based intervention to improve virologic suppression among youth and young adults living with HIVNIHNational Institute of Mental Health2022 to 2025$3,886,971September 1, 2022June 30, 2027SABERI, PARYAreporter.nih.gov
The Spine Phenome Project: Enhancing Patient DiversityNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$3,879,795September 26, 2019August 31, 2024MARRAS, WILLIAM STEVENreporter.nih.gov
Understanding the links between parental and adolescent substance use:complementary natural experiments using the children of twins designNIHNational Institute on Drug Abuse2022 to 2025$3,871,138May 1, 2022February 28, 2027RHEE, SOO Hreporter.nih.gov
Making Better Decisions: Policy Modeling for AIDS and Drug AbuseNIHNational Institute on Drug Abuse2021 to 2025$3,865,844September 25, 2022January 31, 2029OWENS, DOUGLAS Kreporter.nih.gov
A Gene Drive Therapy for HIV: single-administration intervention for high-risk groupsNIHNational Institute on Drug Abuse2021 to 2024$3,842,823April 15, 2020August 31, 2024WEINBERGER, LEOR Sreporter.nih.gov
An automated portable system for detecting and treating opioid induced respiratory depressionNIHNational Institute on Drug Abuse2022 to 2024$3,830,637April 1, 2022February 28, 2026MACKIE, KENNETHreporter.nih.gov
Optical Tools to Assess the Role of Cardiac Function in the Development of Congenital Heart DefectsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,824,765July 1, 2015February 28, 2027JENKINS, MICHAEL W.reporter.nih.gov
Immune Dysfunction in HIV+ Opioid UsersNIHNational Institute on Drug Abuse2021 to 2025$3,823,539April 15, 2020January 31, 2027PAHWA, SAVITAreporter.nih.gov
Consortium on Methods Evaluating Tobacco (COMET): FilterVentilation and Product StandardsNIHNational Cancer Institute2021 to 2022$3,820,230September 20, 2017August 31, 2024HATSUKAMI, DOROTHY Kreporter.nih.gov
Dissecting the Interoception Circuit that Controls Airway ConstrictionNIHNational Center for Complementary & Integrative Health2021 to 2025$3,805,305September 1, 2021August 31, 2026SUN, XINreporter.nih.gov
The Emergency Department Longitudinal Integrated Care (ED-LINC) Effectiveness Randomized Trial Targeting Opioid Use and Related Comorbidity from the EDNIHNational Institute on Drug Abuse2021 to 2025$3,800,864August 1, 2021June 30, 2027WHITESIDE, LAUREN Kreporter.nih.gov
The Effects of Cannabis Legalization and Persistent Use: A Longitudinal Study of Two Twin CohortsNIHNational Institute on Drug Abuse2021 to 2025$3,800,554September 1, 2017April 30, 2029ELLINGSON, JARROD MARTINreporter.nih.gov
Development and Implementation of a Culturally Centered Opioid Prevention Intervention for American Indian/Alaska Native Young Adults in CaliforniaNIHNational Institute on Drug Abuse2021 to 2023$3,791,983September 30, 2019August 31, 2025D'AMICO, ELIZABETH J.reporter.nih.gov
Expanding the potential of couples HIV testing: Adjunct modules to reduce drug use among vulnerable male couplesNIHNational Institute on Drug Abuse2021 to 2024$3,790,611July 15, 2020May 31, 2026STARKS, TYREL Jreporter.nih.gov
Heavy cannabis use, neurocognition and PrEP care engagement among young Black sexual minority menNIHNational Institute on Drug Abuse2022 to 2025$3,790,453September 15, 2022June 30, 2027SCHNEIDER, JOHNreporter.nih.gov
Molecular genetic mechanisms of opioid receptor signalingNIHNational Institute on Drug Abuse2021 to 2025$3,788,093September 15, 2019April 30, 2029GRILL, BROCKreporter.nih.gov
Electronic Pediatric Office Systems to Support Treatment for Parental Tobacco UseNIHNational Cancer Institute2021 to 2024$3,780,101January 1, 2020December 31, 2025WINICKOFF, JONATHAN Preporter.nih.gov
Effect of buprenorphine on monocytes in the context of neuroAids and opioid abuseNIHNational Institute on Drug Abuse2021 to 2025$3,772,066April 15, 2017July 31, 2027BERMAN, JOAN WEINBERGERreporter.nih.gov
15/24- Healthy Brain and Child Development National ConsortiumNIHNational Institute on Drug Abuse2021 to 2023$3,749,834September 30, 2021June 30, 2024SCOTT, LISA S.reporter.nih.gov
Spatio-temporal Methods for Surveillance of the Opioid SyndemicNIHNational Institute on Drug Abuse2021 to 2025$3,748,657September 1, 2025August 31, 2029KLINE, DAVID Mreporter.nih.gov
Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse BrainNIHNational Institute on Drug Abuse2021 to 2025$3,747,870August 1, 2021May 31, 2027AKBARIAN, SCHAHRAMreporter.nih.gov
Project SMART: Social Media Anti-vaping Messages to Reduce ENDS Use Among Sexual and Gender Minority TeensNIHNational Institute on Drug Abuse2021 to 2025$3,741,884July 1, 2021April 30, 2027TAN, ANDY SLreporter.nih.gov
Kentucky BIRCWH Program: Training the Next Generation of Women's Health ScholarsNIHNational Institute on Drug Abuse2021 to 2025$3,736,408August 1, 2022July 31, 2027CURRY, THOMAS Ereporter.nih.gov
Cannabis and Pathogenic Mechanisms influencing Blood Brain Barrier Function in HIVNIHNational Institute on Drug Abuse2023 to 2025$3,726,178August 15, 2023June 30, 2028IUDICELLO, JENNIFER Ereporter.nih.gov
Efficacy of a PrEP uptake & Adherence Intervention among male sex workers using a 2-stage randomization designNIHNational Institute of Nursing Research2021 to 2025$3,717,256July 8, 2021March 31, 2027BIELLO, KATIE BROOKSreporter.nih.gov
Community Randomized Trial in the Cherokee Nation: CONNECT and CMCA for Preventing Drug Misuse among Older AdolescentsNIHNational Institute on Drug Abuse2021 to 2023$3,708,886September 30, 2019August 31, 2025KOMRO, KELLI ANNreporter.nih.gov
Persistent HIV-1 expression and microglia dysfunctionNIHNational Institute on Drug Abuse2021 to 2025$3,708,561August 1, 2021May 31, 2027HENDERSON, ANDREW Jreporter.nih.gov
Registration of spatial gene expression in key nodes of reward-related circuitry in the human brainNIHNational Institute on Drug Abuse2021 to 2025$3,694,469September 30, 2021April 30, 2027MARTINOWICH, KERIreporter.nih.gov
Evaluation of Clinical Effectiveness, Cost, and Implementation Factors to Optimize Scalability of Treatment for Co-Occurring SUD and PTSD Among TeensNIHNational Institute on Drug Abuse2021 to 2025$3,681,626August 15, 2021June 30, 2027DANIELSON, CARLA KMETTreporter.nih.gov
The Comparative Effectiveness and Safety of Pharmacotherapies for the Treatment of Opioid Use Disorder in PregnancyNIHNational Institute on Drug Abuse2021 to 2025$3,680,536April 1, 2020May 31, 2029HUYBRECHTS, KRISTA Freporter.nih.gov
Collaborative care teams for hospitalized patients with opioid use disorders: Translating evidence into practiceNIHNational Center for Advancing Translational Sciences2021 to 2023$3,678,409June 1, 2020May 31, 2025DANOVITCH, ITAIreporter.nih.gov
Case-Control Study of Methamphetamine in Pulmonary Arterial HypertensionNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,677,031August 20, 2021May 31, 2027KAWUT, STEVEN Mreporter.nih.gov
National Consortium on Alcohol and NeuroDevelopment in Adolescence - SRI International Research Project Site (NCANDA-SRI)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,664,453September 5, 2012June 30, 2027BAKER, FIONA Creporter.nih.gov
Understanding neuronal subtype-specific function of NAc in cocaine addictionNIHNational Institute on Drug Abuse2021 to 2025$3,661,419April 1, 2021February 28, 2026ZHANG, YIreporter.nih.gov
Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C UCB J PET StudyNIHNational Institute on Drug Abuse2021 to 2025$3,657,020July 1, 2021April 30, 2027ANGARITA, GUSTAVO ADOLFOreporter.nih.gov
Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$3,648,087September 25, 2021August 31, 2025GUSTAFSON, DAVID Hreporter.nih.gov
Visual biofeedback to reduce head motion during MRI scansNIHNational Institute of Mental Health2021 to 2022$3,644,531September 11, 2019May 31, 2024ROTHNEY, MEGAN PEARLreporter.nih.gov
ADAPT: Adaptive Decision support for Addiction TreatmentNIHNational Institute on Drug Abuse2023 to 2025$3,638,873September 30, 2023July 31, 2028MELNICK, EDWARD ROBERTreporter.nih.gov
Evaluating Suvorexant for Sleep Disturbance in Opioid Use DisorderNIHNational Institute on Drug Abuse2021$3,632,165April 1, 2019August 31, 2025HUHN, ANDREW Sreporter.nih.gov
Assessment of Biomarkers in Children to Help Parents Quit TobaccoNIHNational Cancer Institute2021 to 2025$3,629,865September 1, 2020June 30, 2026WINICKOFF, JONATHAN Preporter.nih.gov
Alliance to Disseminate Addiction Prevention and Treatment (ADAPT): A Statewide Learning Health System to Reduce Substance Use among Justice-Involved Youth in Rural Communities.NIHNational Institute on Drug Abuse2021 to 2023$3,626,057September 30, 2019April 30, 2026AALSMA, MATTHEWreporter.nih.gov
NIAAA PUBLICATIONS AND EXHIBITS SUPPORTNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2024$3,626,040March 21, 2023March 20, 2025MOYER, MELINDA MOYERreporter.nih.gov
Cannabis use, PrEP and HIV transmission riskNIHNational Institute on Drug Abuse2021 to 2025$3,624,329August 1, 2021May 31, 2027DUNCAN, DUSTIN Treporter.nih.gov
Prazosin Treatment for Alcohol Use Disorder with Alcohol Withdrawal SymptomsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,615,761May 15, 2021February 28, 2027SINHA, RAJITAreporter.nih.gov
Advancing KNX100 for the treatment of opioid withdrawal: preclinical efficacy and toxicology, and a phase 1 clinical program.NIHNational Institute on Drug Abuse2023 to 2025$3,603,973September 30, 2019May 31, 2026ALSOP, HUGH WILLIAMreporter.nih.gov
EMBED: Pragmatic trial of user-centered clinical decision support to implement EMergency department-initiated BuprenorphinE for opioid use DisorderNIHNational Institute on Drug Abuse2021 to 2022$3,603,411April 1, 2018September 30, 2024MELNICK, EDWARD ROBERTreporter.nih.gov
Development of a Safer and More Effective Ibogaine Analog for the Treatment of Opioid Use DisorderNIHNational Institute on Drug Abuse2024 to 2025$3,588,425March 1, 2024October 17, 2025MAREK, GERARD JOSEPHreporter.nih.gov
Small molecule modulators of ΔFosBNIHNational Institute on Drug Abuse2021 to 2025$3,586,553July 1, 2016March 31, 2027RUDENKO, GABRIELLEreporter.nih.gov
NIH BRAIN DEVELOPMENT COHORTS DATA SHARING PLATFORM. PERIOD OF PERFORMANCE 4/19/2024 - 4/18/2026.NIHNational Institute on Drug Abuse2025$3,584,505April 19, 2024April 18, 2025reporter.nih.gov
Effects of Cannabidiol and Tetrahydrocannabinol on the Microbiome, Endocannabinoids and Neuroinflammation in HIVNIHNational Institute on Drug Abuse2022 to 2025$3,584,464June 15, 2022March 31, 2027ELLIS, RONALD J.reporter.nih.gov
Cannabidiol for postoperative Opioid Reduction in primary total Knee arthroplasty – a randomized, 2x2 factorial, double-blind, placebo-controlled clinical trial (The CORK trial)NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$3,579,362September 18, 2023August 31, 2028BRUMMETT, CHAD Mreporter.nih.gov
Brain Myeloid Cells are Sources of HIV-associated Damage and Viral DispersalNIHNational Institute on Drug Abuse2021 to 2025$3,578,599July 15, 2021April 30, 2027CHAILLON, ANTOINEreporter.nih.gov
Origin of Cortical Species-specific DistinctionsNIHNational Institute on Drug Abuse2021 to 2025$3,571,176April 1, 2025March 31, 2030RAKIC, PASKOreporter.nih.gov
Phase 1a/1b Clinical Trials of Multivalent Opioid Vaccine ComponentsNIHNational Institute on Drug Abuse2023$3,569,552September 15, 2018March 31, 2028COMER, SANDRA Dreporter.nih.gov
Training in the pharmacology of abused drugsNIHNational Institute on Drug Abuse2021 to 2025$3,567,642July 1, 1976June 30, 2026DEWEY, WILLIAM L.reporter.nih.gov
Molecular Engineering of Natural Light-Gated Chloride Channels for Optogenetic InhibitionNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$3,563,048August 15, 2020August 31, 2025XUE, MINGSHANreporter.nih.gov
Recreational Marijuana Marketing and Young Adult Consumer BehaviorNIHNational Institute on Drug Abuse2022 to 2025$3,562,253April 1, 2022February 28, 2027BERG, CARLA Jreporter.nih.gov
Development of a 3-month implantable depot pellet of Naltrexone for the treatment of Opioid Use Disorder.NIHNational Institute on Drug Abuse2021 to 2022$3,552,798March 1, 2022August 31, 2023MALLON, ANDREW PETERreporter.nih.gov
Fructokinase Inhibitors for the Treatment of Alcohol Use DisorderNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$3,549,138September 23, 2019June 30, 2025JOHNSON, RICHARD JOSEPHreporter.nih.gov
Interactions between neutrophils and cholangiocytes in alcoholic hepatitisNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,548,231September 25, 2021June 30, 2027NATHANSON, MICHAEL Hreporter.nih.gov
Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation InterventionNIHNational Center for Complementary & Integrative Health2021 to 2025$3,545,738September 27, 2021August 31, 2027GORDON, JUDITH SARAHreporter.nih.gov
PTPRD Phosphatase inhibitors for stimulant use disordersNIHNational Institute on Drug Abuse2022 to 2024$3,540,141July 1, 2022June 30, 2025UHL, GEORGE RICHARDreporter.nih.gov
Kipiyeecipsakiciipe "coming home": Establishing clinical cultural neuroscience as a tool for understanding the role of traditional cultural engagement in mitigating substance misuse and disorderNIHNational Institute on Drug Abuse2023 to 2025$3,538,500July 1, 2023May 31, 2028WHITE, EVAN JAMESreporter.nih.gov
Synthetics in Combination (SYNC)NIHNational Institute on Drug Abuse2021 to 2025$3,536,582September 30, 2021June 30, 2026CICCARONE, DANIEL Hreporter.nih.gov
Digital smoking cessation intervention for nationally-recruited American Indians and Alaska Natives: A full-scale randomized controlled trialNIHNational Cancer Institute2023 to 2025$3,532,837September 20, 2023August 31, 2028BRICKER, JONATHAN Breporter.nih.gov
Inter- and Intra-cellular effects of cannabinoids, HIV and ART in the CNSNIHNational Institute on Drug Abuse2021 to 2025$3,529,874August 1, 2020May 31, 2027JORDAN-SCIUTTO, KELLY Lreporter.nih.gov
Prediction of Alcohol Use Disorder and PTSD After Trauma in AdolescentsNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$3,522,916September 5, 2022June 30, 2027NEMEROFF, CHARLES Breporter.nih.gov
Impact of the COVID-19 pandemic on patient outcomes, telehealth care delivery, and treatment for unhealthy alcohol use in vulnerable patients with advanced liver disease across two healthcare systemsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,517,747June 1, 2021February 28, 2027KHALILI, MANDANAreporter.nih.gov
Acetylcholine signaling allows cognitive processes in the brain to regulate physiological responses to the environment: the example of central control of opiate toleranceNIHNational Institute on Drug Abuse2021 to 2023$3,517,500August 15, 2019July 31, 2025PICCIOTTO, MARINA Rreporter.nih.gov
Sleep and circadian rhythm phenotypes and mechanisms associated with opioid use disorder treatment outcomesNIHNational Institute on Drug Abuse2023 to 2025$3,516,481September 30, 2023August 31, 2027HUHN, ANDREW Sreporter.nih.gov
Development of JR-220 (4-Chlorobenzylidenamino-guanidine hydrochloride) as a medication for alcohol dependenceNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$3,514,532August 25, 2017August 31, 2025BURKLOW, CINDY ANNreporter.nih.gov
Prescription Opioid Misuse: A Pharmacist-Led Intervention at Point of Service Efficacy TrialNIHNational Institute on Drug Abuse2021 to 2025$3,513,979March 15, 2021January 31, 2027COCHRAN, GERALD T.reporter.nih.gov
Mouse Phenome ProjectNIHNational Institute on Drug Abuse2021 to 2025$3,508,713July 1, 2004December 31, 2029BOGUE, MOLLY Areporter.nih.gov
Harnessing Highly Networked HLA-E-Restricted CTL Epitopes to Achieve a Broadly Effective HIV CureNIHNational Institute on Drug Abuse2023 to 2025$3,507,000April 1, 2023February 29, 2028GAIHA, GAURAV DASreporter.nih.gov
Efficacy of a Trauma Intervention for Affect Regulation, Adherence, and Substance Use to Optimize PrEP for Women Who Inject DrugsNIHNational Institute on Drug Abuse2021 to 2025$3,503,654July 1, 2021April 30, 2027ROTH, ALEXIS MARIEreporter.nih.gov
Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications, and CBT4CBT: A randomized clinical trial in a diverse patient populationNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,501,674September 20, 2021May 31, 2027EDELMAN, E. JENNIFERreporter.nih.gov
Craniofacial Morphogenesis in Prenatal Alcohol ExposureNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,497,846July 1, 1996August 31, 2029SMITH, SUSAN M.reporter.nih.gov
Opioid therapy for pain in individuals with metastatic cancer: benefits, harms and stakeholder perspectivesNIHNational Institute of Nursing Research2021 to 2025$3,491,253September 15, 2021June 30, 2027WHITE, GRETCHENreporter.nih.gov
Partnering to Achieve Wellness for Native Americans through Indigenous Knowledge (PAWNIK)NIHNational Institute on Drug Abuse2024 to 2025$3,488,602September 9, 2024August 31, 2026D'AMICO, ELIZABETH J.reporter.nih.gov
Characterization of Tandem Repeat and Structural Variants Contributing to Addictive Behaviors in Mice and RatsNIHNational Institute on Drug Abuse2021 to 2025$3,486,254May 1, 2021February 28, 2027PALMER, ABRAHAM Areporter.nih.gov
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)NIHNational Heart, Lung, and Blood Institute2023 to 2025$3,483,414September 10, 2020August 31, 2027CASKEY, RACHELreporter.nih.gov
Social influences on choices in adolescent substance useNIHNational Institute on Drug Abuse2021 to 2025$3,476,235April 1, 2021January 31, 2027CASAS, BROOKSreporter.nih.gov
mHealth Messaging to Motivate Quitline use and Quitting among Persons Living With HIV in Vietnam (M2Q2-HIV)NIHNational Cancer Institute2021 to 2025$3,472,107September 17, 2021August 31, 2027SADASIVAM, RAJANIreporter.nih.gov
Center for chronic pain and drug abuseNIHNational Institute on Drug Abuse2021 to 2022$3,471,757September 1, 2018June 30, 2025APKARIAN, APKAR VANIAreporter.nih.gov
NEUROPSYCHOPHARMACOLOGY: MULTIDISCIPLINARY TRAININGNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,469,477December 1, 1983June 30, 2027ROBERTO, MARISAreporter.nih.gov
Identifying Roadblocks to Antigen Expression and Enhancing Killing of HIV-Infected Cells That Are Refractory to ClearanceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,468,805March 2, 2023February 29, 2028JOSEPH, SARAH BETHreporter.nih.gov
Five Point Initiative: A Cluster Randomized Trial of a Bundled Implementation Strategy to Address the HIV Epidemic in Black CommunitiesNIHNational Institute of Mental Health2023 to 2025$3,468,105August 5, 2023May 31, 2028DALE, SANNISHA Kreporter.nih.gov
Project Recognize: Improving Measurement of Alcohol Use and Demographic Factors through Community EngagementNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,467,461September 21, 2021December 18, 2026PHILLIPS, GREGORY L.reporter.nih.gov
Prapela® SVS incubator pad: A cost-effective stochastic vibrotactile device to improve the clinical course of infants with apnea of prematurity.NIHNational Institute on Drug Abuse2023 to 2025$3,460,586April 1, 2023March 31, 2027KONSIN, JOHN PHILLIPreporter.nih.gov
Integrated, Individualized, and Intelligent Prescribing (I3P) Clinical Trial NetworkNIHNational Human Genome Research Institute2021 to 2024$3,458,289July 1, 2024June 30, 2025PETERSON, JOSEPH F.reporter.nih.gov
J-RISE: Relevant Implementation Strategies to Enhance access to care and employment among individuals who have been impacted by the criminal legal systemNIHNational Institute of Mental Health2023 to 2025$3,453,087September 15, 2023June 30, 2028BREWER, RUSSELLreporter.nih.gov
Nalmefene Implant for the Long-Term Treatment of Opioid Use DisorderNIHNational Institute on Drug Abuse2025$3,450,000September 15, 2018January 31, 2028PATEL, RAJESH Areporter.nih.gov
Allosteric Modulators of Dopamine Transporter as Therapeutic Agents for NeuroAIDSNIHNational Institute on Drug Abuse2021 to 2024$3,446,099July 1, 2020April 30, 2026AUGELLI-SZAFRAN, CORINNE ELIZABETHreporter.nih.gov
Peer-Delivered, Behavioral Activation Intervention to Improve Polysubstance Use and Retention in Mobile Telemedicine OUD Treatment in an Underserved, Rural AreaNIHNational Institute on Drug Abuse2022 to 2025$3,434,019September 30, 2022August 31, 2027MAGIDSON, JESSICA Freporter.nih.gov
UnityPhilly Response App for Overdose Reversal: Assessing Citywide Effectiveness and SustainabilityNIHNational Institute on Drug Abuse2023 to 2025$3,424,229September 30, 2023July 31, 2028LANKENAU, STEPHEN Ereporter.nih.gov
SAIA-PrEP: a systems analysis and improvement approach to optimize PrEP implementation in syringe service programsNIHNational Institute on Drug Abuse2022 to 2025$3,418,213September 1, 2022June 30, 2027BAZZI, ANGELA ROBERTSONreporter.nih.gov
Childhood, Adolescence, and Covid-Related Risk and Protective Factors in the Development of Adjustment in Early Adulthood Across CulturesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,417,415September 30, 2007May 31, 2027LANSFORD, JENNIFER Ereporter.nih.gov
The Secret Lives of RNA: The In Vivo 3D-Structural Logic of Single Neuron RNA MetabolismNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2023$3,412,500September 30, 2019July 31, 2024EBERWINE, JAMES Hreporter.nih.gov
Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trialsNIHNational Institute on Drug Abuse2025$3,410,308September 30, 2022July 31, 2028PRAVETONI, MARCOreporter.nih.gov
Preclinical and clinical evaluation of the NMDA modulator NYX-783 for OUDNIHNational Institute on Drug Abuse2022$3,406,895September 30, 2019September 29, 2025SINHA, RAJITAreporter.nih.gov
Integrating Tailored Postoperative Opioid Tapering and Pain Management Support for Patients on Long-Term Opioid Use Presenting for Spine Surgery (MIRHIQL)NIHNational Institute on Drug Abuse2023$3,406,550August 15, 2023July 31, 2026HAH, JENNIFERreporter.nih.gov
Prevalence, onset and progression of substance use in adolescents and young adults with Autism Spectrum DisordersNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,400,621February 5, 2021January 31, 2027SPIRITO, ANTHONYreporter.nih.gov
Psychedelics for Older Adults with Chronic PainNIHNational Institute on Aging2025$3,399,999August 15, 2025July 31, 2027FISCHER, STACY Mreporter.nih.gov
Respiratory Sinus Arrhythmia as a Predictor of Substance Use among Early AdolescentsNIHNational Institute on Drug Abuse2021 to 2025$3,393,809September 1, 2021June 30, 2027HOUCK, CHRISTOPHER D.reporter.nih.gov
Genetics of oxycodone intake in a hybrid rat diversity panel.NIHNational Institute on Drug Abuse2021 to 2025$3,392,750April 15, 2021January 31, 2027SHARP, BURT Mreporter.nih.gov
Evaluating the impact of fentanyl test strip use among rural and urban populationsNIHNational Institute on Drug Abuse2021 to 2025$3,392,442July 1, 2021April 30, 2027MICHAELS, NICHOLE Lreporter.nih.gov
Optimizing evidence-based HIV prevention targeting people who inject drugs on PrEPNIHNational Institute on Drug Abuse2022 to 2025$3,386,037September 1, 2022June 30, 2027COPENHAVER, MICHAELreporter.nih.gov
Evaluation of a community-based education, navigation, and support (CENS) intervention to reduce opioid-related harms among military veteransNIHNational Institute on Drug Abuse2021 to 2025$3,379,762September 30, 2021July 31, 2027BENNETT, ALEXANDER Sreporter.nih.gov
Social Norms & Skills Training: Motivating Campus ChangeNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,378,502September 27, 1999June 30, 2028LARIMER, MARY E.reporter.nih.gov
Molecular underpinnings of the developmental Effects of CannabisNIHNational Institute on Drug Abuse2022 to 2025$3,375,521August 15, 2022May 31, 2027HURD, YASMIN L.reporter.nih.gov
Secondhand Harms from Alcohol & Drugs: Impacts on Families and Communities across the USNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,368,295September 20, 2021June 30, 2027KERR, WILLIAM C.reporter.nih.gov
Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention ToolkitNIHNational Cancer Institute2021 to 2025$3,364,734September 2, 2021August 31, 2026HALPERN-FELSHER, BONNIE Lreporter.nih.gov
Applying Digital Health to the AF Ablation NCDR, Enabling Longitudinal Follow-upNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,363,830September 16, 2021July 31, 2026MARCUS, GREGORY Mreporter.nih.gov
Biophysical Mechanisms of Cortical MicroStimulationNIHNational Institute of Neurological Disorders and Stroke2023$3,360,184September 6, 2023August 31, 2026CASH, SYDNEY Sreporter.nih.gov
Cultural Stress, Stress Response, and Substance Use among Hispanic AdolescentsNIHNational Institute on Drug Abuse2021 to 2025$3,353,718September 1, 2021June 30, 2027SCHWARTZ, SETH J.reporter.nih.gov
Pediatric Adverse Event Risk Reduction for High Risk Medications in Children and Adolescents: Improving Pediatric Patient Safety in Dental PracticesNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,353,166August 4, 2022April 30, 2027SUDA, KJreporter.nih.gov
Discreet Wearable device for Continuous Real-time Monitoring of AlcoholNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$3,351,618September 1, 2022July 31, 2026TEHRANI, FARSHADreporter.nih.gov
Epigenetic mechanisms of sustained transcription across cocaine abstinenceNIHNational Institute on Drug Abuse2021 to 2025$3,351,544July 1, 2021May 31, 2026HELLER, ELIZABETH Areporter.nih.gov
Leveraging regulatory flexibility for methadone take-home dosing to improve retention in treatment for opioid use disorder: A stepped-wedge randomized trial to facilitate clinic level changesNIHNational Institute on Drug Abuse2023 to 2025$3,350,010September 30, 2022August 31, 2027NEIGHBORS, CHARLES Jreporter.nih.gov
Promoting remote and secondary risk prevention services in rural settingsNIHNational Institute on Drug Abuse2022 to 2025$3,349,340September 30, 2022July 31, 2027PHO, MAI TUYETreporter.nih.gov
Drug development of clavulanic acid, a GLT-1 activator: proof of concept for cocaine use disorderNIHNational Institute on Drug Abuse2022 to 2023$3,340,215May 15, 2020December 31, 2024MORRISON, MARY F.reporter.nih.gov
BRAIN CONNECTS: High-Throughput Single Cell Projection Mapping and Spine Quantification in the Primate Brain by Synaptic BarcodingNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$3,335,014August 31, 2024July 31, 2027MACOSKO, EVAN Zreporter.nih.gov
9/10 Electrophysiology of Alcohol in Extended AmygdalaNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,330,627September 27, 2001January 31, 2027ROBERTO, MARISAreporter.nih.gov
Fatal Overdose Review Teams - Research to Enhance Surveillance Systems (FORTRESS)NIHNational Institute on Drug Abuse2024$3,330,528September 30, 2022August 31, 2027AALSMA, MATTHEWreporter.nih.gov
Wake Forest IMPOWR Dissemination Education and Coordination Center (IDEA-CC)NIHNational Institute on Drug Abuse2021 to 2023$3,329,368September 30, 2021July 31, 2027ADAMS, MEREDITH C. B.reporter.nih.gov
Alcohol Use Disorder Treatment Simulation: Modeling treatment impacts on alcohol-related disparitiesNIHNational Institute on Alcohol Abuse and Alcoholism2022 to 2025$3,328,534April 10, 2022February 28, 2027KARRIKER-JAFFE, KATHERINE J.reporter.nih.gov
ALCOHOL POLICY INFORMATION SYSTEMNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$3,328,286January 1, 2018February 10, 2023HERRON, KATHERYNreporter.nih.gov
Functional consequences of fetal-alcohol-induced brain growth abnormalities identified with in utero MRINIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,326,416May 1, 2021February 28, 2027CUZON CARLSON, VERGINIA CARMELLAreporter.nih.gov
Personalized Integrated Alcohol and Sexual Assault Prevention among College StudentsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,321,878September 25, 2021May 31, 2027GILMORE, AMANDA KATHERINEreporter.nih.gov
Evaluating naloxone-on-release from incarceration as community overdose preventionNIHNational Institute on Drug Abuse2022 to 2025$3,318,365June 15, 2022April 30, 2027DAVIDSON, PETER JOHNreporter.nih.gov
Optimizing PrEP Implementation and Cost-effectiveness among Individuals with a Substance Use DisorderNIHNational Institute on Drug Abuse2022 to 2025$3,316,145September 1, 2022September 17, 2025REBACK, CATHY Jreporter.nih.gov
7/7 Psychiatric Genomics Consortium: Advancing Discovery and ImpactNIHNational Institute on Drug Abuse2021 to 2025$3,313,224April 1, 2021January 31, 2027AGRAWAL, ARPANAreporter.nih.gov
Phase 1 and 2 studies of sublingual dexmedetomidine, an alpha 2 adrenergic agonist, for treating opioid withdrawalNIHNational Institute on Drug Abuse2022$3,312,204August 1, 2022July 31, 2025LEVIN, FRANCES RUDNICKreporter.nih.gov
Discovery of PSD95 protein-protein interaction inhibitors as novel non-opioid analgesicsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,311,688March 1, 2021February 28, 2026FLORIO, STEPHANIE Kreporter.nih.gov
Project Nurture Expansion StudyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,304,098September 24, 2021August 31, 2026COHEN, DEBORAH JILLreporter.nih.gov
Medications for opioid use disorder differentially modulate intrinsically photosensitive retinal ganglion cell function, sleep, and circadian rhythms: implications for treatmentNIHNational Institute on Drug Abuse2023 to 2025$3,303,776September 30, 2023August 31, 2027CROPSEY, KAREN Lreporter.nih.gov
A community-based trial of a voluntary smoke-free home intervention in permanent supportive housing for formerly homeless adultsNIHNational Cancer Institute2021 to 2025$3,303,677March 3, 2021February 28, 2026VIJAYARAGHAVAN, MAYAreporter.nih.gov
Perioperative Precision Medicine: Translating Science to Clinical Practice to Improve Safety and Efficacy of Opioids in Neonates, Children and Nursing MothersNIHNational Center for Advancing Translational Sciences2022 to 2024$3,295,714August 3, 2022April 30, 2027SADHASIVAM, SENTHILKUMARreporter.nih.gov
A geospatial analysis of hotspots and targeted injection settings pilot intervention for HIV prevention among people who inject drugs in Baltimore, MarylandNIHNational Institute on Drug Abuse2021 to 2025$3,292,995July 1, 2020May 31, 2027LATKIN, CARL Areporter.nih.gov
Understanding Social Support Network Characteristics, Alcohol Misuse, and Posttraumatic Stress among Survivors of Sexual Assault in the First-year Post-assaultNIHNational Institute on Alcohol Abuse and Alcoholism2025$3,291,402September 11, 2025August 31, 2029JAFFE, ANNA E.reporter.nih.gov
Assessing the Effects of Cigar and Cigarillo Social Media Promotion on Tobacco and Marijuana UseNIHNational Cancer Institute2021 to 2025$3,291,137December 2, 2020November 30, 2026KOSTYGINA, GANNAreporter.nih.gov
Genomic and Epigenomic Mechanisms of Maternal E-Cigarette induced Abnormal Brain DevelopmentNIHNational Institute on Drug Abuse2023 to 2025$3,290,961April 15, 2023January 31, 2028WANG, CHARLESreporter.nih.gov
Sequential Trial of Adding Buprenorphine, Cognitive Behavioral Treatment, and Transcranial Magnetic Stimulation to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION)NIHNational Institute on Drug Abuse2023$3,290,624August 15, 2023July 31, 2026BARTH, KELLY S.reporter.nih.gov
A savings intervention to reduce men's engagement in HIV risk behaviorsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,287,361April 1, 2021March 30, 2027THIRUMURTHY, HARSHAreporter.nih.gov
Single-cell Proteogenomic profiling of HIV-1 reservoir cellsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,287,170March 20, 2023February 28, 2026LICHTERFELD, MATHIASreporter.nih.gov
IND-enabling studies and phase I clinical trials to advance CD74-target, DRhQ, as a treatment for stimulant use disorderNIHNational Institute on Drug Abuse2025$3,287,052May 15, 2025April 30, 2027SHIRLEY, RENEE LYNNreporter.nih.gov
A Female-Specific Cognitive Behavioral Therapy Group for Alcohol Use Disorder in VA Primary Care SettingsNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,280,364February 5, 2021January 31, 2027EPSTEIN, ELIZABETH ELLENreporter.nih.gov
Using Sleep Health to Optimize Smoking Cessation Treatment Response in HIV-Positive AdultsNIHNational Institute on Drug Abuse2021 to 2024$3,280,008July 1, 2020May 31, 2025FANTRY, LORI Ereporter.nih.gov
Prospective evaluation of outcomes in cirrhosis of different etiologies: impact of HIV infection and simvastatin therapyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,276,651September 23, 2021July 31, 2027DASARATHY, SRINIVASANreporter.nih.gov
Stagewise Implementation-To-Target- Medications for Addiction Treatment (SITT-MAT)NIHNational Institute on Drug Abuse2021 to 2025$3,276,074September 1, 2021June 30, 2027MCGOVERN, MARK Preporter.nih.gov
PrEP and MOUD Rapid Access for Persons who Inject Drugs: the CHORUS+ StudyNIHNational Institute on Drug Abuse2023 to 2025$3,275,988September 1, 2023June 30, 2028ASSOUMOU, SABRINA Areporter.nih.gov
Reducing Alcohol Involved Sexual violence in higher Education (RAISE)NIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,275,604August 20, 2014May 31, 2027KAZMERSKI, TRACI Mreporter.nih.gov
Alcohol's Effects on Affective, Cognitive, and Behavioral Responses in a Virtual Reality Dating SimulationNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,272,691September 22, 2021August 31, 2027ABBEY, ANTONIAreporter.nih.gov
The impact of central sleep apnea in patients receiving medications for opioid use disorderNIHNational Institute on Drug Abuse2023 to 2025$3,271,652September 30, 2023August 31, 2027PATEL, SANJAY Rreporter.nih.gov
Clinical markers of neonatal opioid withdrawal syndrome: onset, severity and longitudinal neurodevelopmental outcomeNIHNational Institute on Drug Abuse2021 to 2024$3,270,993April 1, 2020February 28, 2026LESTER, BARRY M.reporter.nih.gov
Epigenetic mechanisms underlying cannabinoid modulation of neuroinflammation in HIV/SIV infectionNIHNational Institute on Drug Abuse2021 to 2024$3,267,557September 30, 2020June 30, 2026MOHAN, MAHESHreporter.nih.gov
Liver Cirrhosis Network: Longitudinal and Clinical Trial StudiesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,258,965September 6, 2021July 31, 2027KHALILI, MANDANAreporter.nih.gov
Vaping Nicotine and Cannabis Across Adolescence and Young AdulthoodNIHNational Cancer Institute2021 to 2024$3,258,517September 20, 2019August 31, 2025LEVENTHAL, ADAM MATTHEWreporter.nih.gov
Advancing knowledge on factors that promote or impede engagement along the HIV care continuum over time: A longitudinal mixed methods study of Black and Latinx youth/emerging adults living with HIVNIHNational Institute on Drug Abuse2021 to 2024$3,258,356July 1, 2021May 31, 2026GWADZ, MARYAreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Yale UniversityNew Haven, CT254$447 million0$0
Johns Hopkins UniversityBaltimore, MD179$388.7 million0$0
University of California, San DiegoLa Jolla, CA166$306.4 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC157$232.4 million0$0
University of California, San FranciscoSan Francisco, CA126$220.3 million0$0
Family Health InternationalDurham, NC1$213.6 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA137$203.4 million0$0
New York University School of MedicineNew York, NY74$191.4 million0$0
University of WashingtonSeattle, WA185$186.2 million0$0
University of Michigan at Ann ArborAnn Arbor, MI112$168.4 million0$0
University of California Los AngelesLos Angeles, CA111$164 million0$0
Medical University of South CarolinaCharleston, SC150$153.5 million0$0
University of KentuckyLexington, KY87$150.6 million0$0
University of PennsylvaniaPhiladelphia, PA103$145.6 million0$0
University of MinnesotaMinneapolis, MN116$141.3 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY93$132 million0$0
Research Triangle InstituteResearch Triangle Park, NC63$128.4 million0$0
Massachusetts General HospitalBoston, MA94$124.8 million0$0
Virginia Commonwealth UniversityRichmond, VA121$116.5 million0$0
Emory UniversityAtlanta, GA66$114.6 million0$0
Brown UniversityProvidence, RI97$110.1 million0$0
Washington UniversitySaint Louis, MO85$109.1 million0$0
Stanford UniversityStanford, CA77$105.7 million0$0
Oregon Health & Science UniversityPortland, OR88$101.2 million0$0
University of Miami School of MedicineCoral Gables, FL42$96.6 million0$0
Northwestern University at ChicagoChicago, IL50$96.5 million0$0
University of FloridaGainesville, FL100$94.3 million0$0
Columbia University Health SciencesNew York, NY75$94.1 million0$0
Wake Forest University Health SciencesWinston-Salem, NC95$93.4 million0$0
Weill Medical Coll of Cornell UnivNew York, NY38$92.3 million0$0
University of Colorado DenverAurora, CO92$91.9 million0$0
Duke UniversityDurham, NC74$87.7 million0$0
The Emmes Company, LLCRockville, MD4$86.8 million0$0
University of Alabama at BirminghamBirmingham, AL54$86 million0$0
University of Maryland BaltimoreBaltimore, MD75$83.2 million0$0
Ohio State UniversityColumbus, OH56$82.1 million0$0
Boston Medical CenterBoston, MA44$78.5 million0$0
Indiana University IndianapolisIndianapolis, IN71$76.8 million0$0
Scripps Research Institute, theLa Jolla, CA50$76.4 million0$0
Albert Einstein College of MedicineBronx, NY36$70.6 million0$0
SUNY Downstate Medical CenterBrooklyn, NY12$65.8 million0$0
University of ChicagoChicago, IL35$65.5 million0$0
University of Illinois at ChicagoChicago, IL65$61.5 million0$0
University of UtahSalt Lake City, UT40$58.1 million0$0
Ut Southwestern Medical CenterDallas, TX20$58 million0$0
University of Wisconsin-MadisonMadison, WI36$58 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ60$57.4 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA47$56.9 million0$0
University of Texas at AustinAustin, TX67$55.5 million0$0
University of Nebraska Medical CenterOmaha, NE51$55.5 million0$0
New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INCNew York, NY42$55.2 million0$0
University of Southern CaliforniaLos Angeles, CA57$51.9 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA50$50.1 million0$0
Rand CorporationSanta Monica, CA31$50 million0$0
Columbia UniversityNew York, NY17$49.1 million0$0
Kaiser Foundation Research InstituteOakland, CA27$43.3 million0$0
Children's Hospital of Los AngelesLos Angeles, CA7$41.1 million0$0
SUNY at BuffaloAmherst, NY42$39.8 million0$0
Boston University Medical CampusBoston, MA36$39.1 million0$0
Pennsylvania State Univ University ParkUniversity Park, PA37$37.5 million0$0
Friends Research Institute, Inc.Baltimore, MD19$36.9 million0$0
University of Texas HLTH Science CenterSan Antonio, TX31$36.9 million0$0
Beth Israel Deaconess Medical CenterBoston, MA14$36.7 million0$0
Wistar InstitutePhiladelphia, PA3$36.6 million0$0
University of Colorado at BoulderBoulder, CO25$36.6 million0$0
Rhode Island HospitalProvidence, RI35$36.2 million0$0
Vanderbilt University Medical CenterNashville, TN27$36.1 million0$0
New York UniversityNew York, NY26$35.7 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA7$35.5 million0$0
Mclean HospitalBelmont, MA34$35.5 million0$0
Florida International UniversityMiami, FL27$35.5 million0$0
LSU Health Sciences CenterNew Orleans, LA54$35.2 million0$0
Vanderbilt UniversityNashville, TN53$34.8 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM28$34.7 million0$0
Intervexion Therapeutics, LLCLittle Rock, AR4$34.6 million0$0
University of CincinnatiCincinnati, OH22$34.2 million0$0
Booz Allen HamiltonMc Lean, VA1$34.2 million0$0
University of California-IrvineIrvine, CA42$34.1 million0$0
Case Western Reserve UniversityCleveland, OH17$33.5 million0$0
Virginia Polytechnic Institute and State UniversityBlacksburg, VA20$32.8 million0$0
Clear Scientific, LLCCambridge, MA7$32.3 million0$0
Sparian Biosciences, Inc.New York City, NY5$32 million0$0
University of Tennessee Health Sci CTRMemphis, TN22$31.4 million0$0
Drexel UniversityPhiladelphia, PA32$31.1 million0$0
Mayo Clinic RochesterRochester, MN28$30.8 million0$0
Dartmouth CollegeHanover, NH15$30.8 million0$0
University of Maryland, College ParkCollege Park, MD27$29.8 million0$0
University of New MexicoAlbuquerque, NM29$29.8 million0$0
George Mason UniversityFairfax, VA10$29.7 million0$0
Hennepin Healthcare Research InstituteMinneapolis, MN7$29.6 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH25$29.4 million0$0
Washington State UniversityPullman, WA31$29.2 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX28$28.8 million0$0
Georgia State UniversityAtlanta, GA27$28 million0$0
National Collegiate Inventors and Innovators AllianceHadley, MA1$27.5 million0$0
University of RochesterRochester, NY26$26.9 million0$0
Arizona State UniversityScottsdale, AZ31$26.5 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA32$26.4 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA13$26.3 million0$0
University of Vermont & ST Agric CollegeBurlington, VT15$26.2 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
20253,494$2,184,462,3790$0
20243,732$2,124,191,3780$0
20233,759$2,166,179,1040$0
20223,677$2,147,319,0860$0
20213,524$2,141,847,0250$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 54 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 16 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 14 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 10 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)PA-24-175NIHMay 7, 2027Not listedNotice number printed on 7 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)PA-24-188NIHMay 7, 2027Not listedNotice number printed on 6 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 4 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 4 awards here
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)PA-24-187NIHMay 7, 2027Not listedNotice number printed on 3 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 3 awards here
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)RFA-DA-25-060NIHMarch 5, 2027$1.5 millionNotice number printed on 2 awards here
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)PA-24-201NIHApril 18, 2027Not listedNotice number printed on 1 award here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIHJanuary 7, 2027$375,000Notice number printed on 1 award here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)PA-24-193NIHMay 7, 2027Not listedNotice number printed on 1 award here
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)PAR-24-089NIHNovember 13, 2026$750,000Notice number printed on 1 award here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIHDecember 3, 2026Not listedNotice number printed on 1 award here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.279November 16, 2026$50,000Same assistance listing 93.279 as 4,540 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.279November 18, 2026Not listedSame assistance listing 93.279 as 4,540 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.279November 18, 2026Not listedSame assistance listing 93.279 as 4,540 awards here
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)PA-23-317NIH93.279November 24, 2026Not listedSame assistance listing 93.279 as 4,540 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.