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Data / Research funding / Skin Cancer

Skin Cancer: 515 NIH awards ($642.9M) to 152 organizations

515 NIH awards ($642.9M) in the NIH spending category Skin Cancer, to 152 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 515 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Spatiotemporal Tumor Analytics for Guiding Sequential Targeted-Inhibitor: Immunotherapy Combinations (ST-Analytics)NIHNational Cancer Institute2022 to 2025$10,596,037September 22, 2022August 31, 2027HEATH, JAMES R.reporter.nih.gov
Biomarker Rich Clinical Trial of an Innovative Antibody Antagonist of TNFR2 in Non-Hodgkin Lymphoma Featuring Cutaneous T Cell Lymphoma (CTCL).NIHNational Cancer Institute2021 to 2025$6,371,380September 1, 2021June 30, 2027BROOKS, DAVID Greporter.nih.gov
NCTN Lead Academic Participating Site at Dana-Farber/Partners Cancer CareNIHNational Cancer Institute2021 to 2025$5,422,908March 5, 2019February 28, 2026BURSTEIN, HAROLD JOHNreporter.nih.gov
Pre-cancer atlas of skin cancerNIHNational Cancer Institute2024 to 2025$5,182,743September 1, 2024August 31, 2029SHAIN, ALAN HUNTERreporter.nih.gov
Identification of Novel Oncogenic Signaling Pathways using Viral PerturbationsNIHNational Cancer Institute2021 to 2025$5,173,906August 8, 2019July 31, 2026DECAPRIO, JAMES A.reporter.nih.gov
Proteogenomic studies to understand mechanisms and drivers of resistance to immunotherapiesNIHNational Cancer Institute2022 to 2025$4,722,849June 16, 2022May 31, 2027PAULOVICH, AMANDA Greporter.nih.gov
Next Generation Cancer Immunotherapies to Defeat MelanomaNIHNational Cancer Institute2021 to 2025$4,577,719September 9, 2015August 31, 2029RIBAS, ANTONIreporter.nih.gov
Genetic and molecular basis for variation in human skin pigmentationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$4,362,884May 1, 2020April 30, 2026MARKS, MICHAEL Sreporter.nih.gov
Immune checkpoint inhibitors and accelerated coronary atherosclerosisNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,014,114May 1, 2022April 30, 2027NEILAN, TOMAS Greporter.nih.gov
Structure, Function and Mechanistic Analysis of LAG3NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,664,179January 8, 2019December 31, 2028VIGNALI, DARIO AAreporter.nih.gov
Bioactive Metabolites Modulate Immune-Related Adverse Events in Cancer ImmunotherapyNIHNational Cancer Institute2021 to 2025$3,549,010July 8, 2021February 28, 2027SHARMA, SONIAreporter.nih.gov
Identification of Lethal Melanomas at the Time of DiagnosisNIHNational Cancer Institute2021 to 2024$3,546,906April 1, 2020March 31, 2026THOMAS, NANCY E.reporter.nih.gov
Role of Trem1 in ultraviolet radiation-induced immune suppressionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,453,128June 18, 2021May 31, 2027YUSUF, NABIHAreporter.nih.gov
Chemical tools for developmental biologyNIHNational Institute of General Medical Sciences2021 to 2025$3,426,216April 1, 2018June 30, 2028CHEN, JAMES Kreporter.nih.gov
Identifying modifiable factors that reduce the burden of late stage melanoma in HispanicsNIHNational Cancer Institute2021 to 2025$3,286,805May 18, 2021April 30, 2027COCKBURN, MYLES Greporter.nih.gov
Evaluation of an implantable microdevice for rapid cancer drug screening directly in T cell lymphoma patientsNIHNational Cancer Institute2021 to 2025$3,235,983July 1, 2020June 30, 2027LAROCCA, CECILIAreporter.nih.gov
Immunotherapy Modeling in Organoids Co-preserving Tumor and Infiltrating Immune CompartmentsNIHNational Cancer Institute2021 to 2025$3,224,380March 17, 2021February 28, 2027KUO, CALVIN Jreporter.nih.gov
Advancing skin cancer prevention by tackling UV-induced clonogenic mutationsNIHNational Cancer Institute2021 to 2025$3,218,488February 3, 2021January 31, 2027WEI, LEIreporter.nih.gov
Pacritinib in rel/refr T-cell lymphomasNIHNational Cancer Institute2021 to 2025$3,194,893September 1, 2021August 31, 2027WILCOX, RYAN Areporter.nih.gov
Technology-Enabled Activation of Skin Cancer Screening for Hematopoietic Cell Transplantation Survivors and their Primary Care ProvidersNIHNational Cancer Institute2021 to 2024$3,192,137April 1, 2020March 31, 2026ARMENIAN, SAROreporter.nih.gov
CD4+ T cells and neoantigens in melanoma immunotherapy.NIHNational Cancer Institute2021 to 2025$3,143,740December 1, 2020November 30, 2026WANG, RONGFUreporter.nih.gov
Eco-evolutionary drivers of clonal dynamics during UV-induced skin carcinogenesis (PQ3)NIHNational Cancer Institute2021 to 2025$3,142,500April 1, 2021March 31, 2027TSAI, KENNETH Yreporter.nih.gov
Small molecule enhancers of tumor immunity targeting the LPA5 GPCRNIHNational Cancer Institute2022 to 2025$3,114,085August 1, 2022July 31, 2026TIGYI, GABOR Jreporter.nih.gov
Fast, large area, multiphoton exoscope (FLAME) for improving early detection of melanomaNIHNational Cancer Institute2022 to 2025$3,098,530September 1, 2022August 31, 2027BALU, MIHAELAreporter.nih.gov
Mechanisms of cAMP-dependent regulation of melanosome pHNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,089,547April 1, 2021March 31, 2026ZIPPIN, JONATHAN HALEreporter.nih.gov
M-ISIC: A Multimodal Open-Source International Skin Imaging Collaboration Informatics Platform for Automated Skin Cancer DetectionNIHNational Cancer Institute2022 to 2025$3,081,926September 1, 2022August 31, 2027ROTEMBERG, VERONICA MIRIAMreporter.nih.gov
Quantitative assessment of pre-metastatic immune subversion as a risk factor for melanoma relapseNIHNational Cancer Institute2022 to 2025$3,027,575September 1, 2022August 31, 2027MARKOVIC, SVETOMIR NENADreporter.nih.gov
Pivotal Clinical Study of the TruScore Device for Non-Invasive Skin Cancer DiagnosticsNIHNational Cancer Institute2022 to 2024$2,999,584May 1, 2016June 30, 2026CHACHISVILIS, MIRIANASreporter.nih.gov
PD-1/PD-L1 modulation in cancer therapyNIHNational Cancer Institute2021 to 2025$2,958,687June 21, 2010February 28, 2027PARDOLL, DREW M.reporter.nih.gov
Phase II Clinical Development of Galectin-3 Inhibition and Anti-PD-1: Immune Monitoring and Tumor ResponseNIHNational Cancer Institute2021 to 2025$2,952,871August 2, 2021July 31, 2027CURTI, BRENDAN Dreporter.nih.gov
A Registry-Based Study of Patterns of Use of Targeted Therapies for Metastatic Cancers in Diverse PopulationsNIHNational Cancer Institute2021 to 2025$2,899,424May 1, 2021November 30, 2025VEENSTRA, CHRISTINEreporter.nih.gov
Development of First-in-Class RIPK1 Degraders to Improve Cancer ImmunotherapiesNIHNational Cancer Institute2022 to 2025$2,872,577July 7, 2022September 2, 2025WANG, JINreporter.nih.gov
Activation of the DNA-PK-dependent antiviral response as a novel cancer immunotherapyNIHNational Cancer Institute2022 to 2025$2,795,412January 20, 2022December 31, 2026STETSON, DANIEL Breporter.nih.gov
Tissue Resident memory T cell responses to cancerNIHNational Cancer Institute2021 to 2025$2,755,604February 12, 2018June 30, 2028TURK, MARY JOreporter.nih.gov
[18F]4FN PET Imaging of Innate Immunity Activation During Immunotherapy-Induced Adverse EventsNIHNational Cancer Institute2022 to 2025$2,714,023September 1, 2022August 31, 2027PIWNICA-WORMS, DAVIDreporter.nih.gov
Gamma delta T cell based melanoma therapiesNIHNational Cancer Institute2022 to 2025$2,700,439December 13, 2021November 30, 2026XU, XIAOWEIreporter.nih.gov
Multiscale Modeling to Optimize Inhibition of Oncogenic ERK Pathway SignalingNIHNational Cancer Institute2021 to 2024$2,681,014February 7, 2020January 31, 2025LEMMON, MARK Areporter.nih.gov
Cancer Resistant MiceNIHNational Cancer Institute2022 to 2025$2,674,668December 1, 2021November 30, 2026BEUTLER, BRUCE Areporter.nih.gov
Immunity to commensal papillomaviruses for cancer therapyNIHNational Cancer Institute2021 to 2025$2,645,679May 1, 2021April 30, 2027DEMEHRI, SHADMEHRreporter.nih.gov
Targeting Lymph Node Dependent Immune Tolerance in CancerNIHNational Cancer Institute2021 to 2025$2,643,851April 1, 2021March 31, 2026ENGLEMAN, EDGAR G.reporter.nih.gov
Role of progenitor exhausted CD8 T cells and the progenitor niche in anti-PD1 efficacyNIHNational Cancer Institute2022 to 2025$2,633,070September 1, 2022August 31, 2027HUANG, ALEXANDERreporter.nih.gov
T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockadeNIHNational Cancer Institute2021 to 2024$2,596,957April 1, 2020March 31, 2025KROGSGAARD, MICHELLEreporter.nih.gov
Resistance mechanisms to autophagy-modulating therapiesNIHNational Cancer Institute2022 to 2025$2,587,243February 15, 2022January 31, 2027AMARAVADI, RAVI Kreporter.nih.gov
Defining the role of NF1 and SPRED1 loss in melanomaNIHNational Cancer Institute2021 to 2025$2,567,516April 1, 2020April 30, 2027YEH, IWEIreporter.nih.gov
Neoadjuvant Immunotherapy with Intratumoral CPG and PD-1 Blockade in MelanomaNIHNational Cancer Institute2021 to 2025$2,557,993March 1, 2021February 28, 2027ZAROUR, HASSANE Mreporter.nih.gov
Genome-wide mutational integration for ultra-sensitive plasma tumor burden monitoring in immunotherapyNIHNational Cancer Institute2022 to 2025$2,537,016June 1, 2022May 31, 2027LANDAU, DANreporter.nih.gov
Functional analysis of a novelintegrin-dependent metastasis pathway in melanomaNIHNational Cancer Institute2021 to 2025$2,532,647December 1, 2020November 30, 2025SCHATTON, TOBIASreporter.nih.gov
Anti-tumor immunity and intestinal microbiota are modulated by mitochondrial DNANIHNational Cancer Institute2022 to 2025$2,514,943May 1, 2022April 30, 2027WALLACE, DOUGLAS Creporter.nih.gov
Dissecting Phenotype Switching in Early Stage MelanomasNIHNational Cancer Institute2022 to 2025$2,502,851August 4, 2022July 31, 2027SCHOBER, MARKUSreporter.nih.gov
Targeting Aldehyde Dehydrogenase for Cancer PreventionNIHNational Cancer Institute2021 to 2024$2,499,798April 15, 2020March 31, 2026ROBERTSON, GAVIN P.reporter.nih.gov
Stromal Regulation of Basal Cell Carcinoma FormationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,499,266July 1, 2001March 31, 2027ORO, ANTHONY Ereporter.nih.gov
The Adenosinergic Pathway in Tumor-derived ExosomesNIHNational Cancer Institute2021 to 2025$2,474,457April 1, 2021March 31, 2027WHITESIDE, THERESA L.reporter.nih.gov
Toward translation of a plant virus-based in situ vaccination nanotechnologyNIHNational Cancer Institute2022 to 2025$2,469,213August 22, 2022July 31, 2026STEINMETZ, NICOLE FRANZISKAreporter.nih.gov
Targeting S6K2 to Overcome Drug Resistance in NRAS-mutant MelanomaNIHNational Cancer Institute2022 to 2025$2,440,545September 1, 2022August 31, 2027VILLANUEVA, JESSIEreporter.nih.gov
Rapid Sample-to-Answer Diagnosis of Kaposi's Sarcoma Across Sub-Saharan Africa using KS-COMPLETENIHNational Cancer Institute2022 to 2025$2,409,286June 10, 2022May 31, 2027ERICKSON, DAVID CARLreporter.nih.gov
Impact of microbiota on AIDS-Kaposi’s sarcoma development and therapyNIHNational Cancer Institute2023 to 2025$2,362,235September 8, 2023August 31, 2028GAO, SHOU-JIANGreporter.nih.gov
An integrated polymeric carrier for subunit cancer vaccinesNIHNational Cancer Institute2021 to 2025$2,360,660March 5, 2021February 28, 2027PUN, SUZIE H.reporter.nih.gov
MITF from control of pigmentation to melanoma riskNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,355,687February 20, 1996February 29, 2028FISHER, DAVID Ereporter.nih.gov
Epigenetic control of skin homeostasis by the ULK3 nuclear kinaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,352,166August 1, 2021April 30, 2026DOTTO, GIAN-PAOLOreporter.nih.gov
Advancing Precision Oncology in a Humanized, Fully Autologous Mouse ModelNIHNational Cancer Institute2021 to 2024$2,342,069March 1, 2020February 28, 2026FIELDS, RYAN Creporter.nih.gov
Combating melanoma resistance by targeting ABL1/2NIHNational Cancer Institute2022 to 2025$2,341,643May 23, 2022April 30, 2027PLATTNER, RINAreporter.nih.gov
Mechanisms of cell death in cutaneous melanomaNIHNational Cancer Institute2021 to 2025$2,341,029June 15, 2021May 31, 2027APLIN, ANDREW ERICreporter.nih.gov
Understanding and Overcoming Resistance to BRAF/MEK Kinase Inhibitors in MelanomaNIHNational Cancer Institute2021 to 2024$2,327,927December 13, 2019November 30, 2025RAJ, ARJUNreporter.nih.gov
Systems analysis of cell-cell communication networks and immune activity in the melanoma tumor microenvironmentNIHNational Cancer Institute2021 to 2024$2,320,897July 1, 2020June 30, 2025MILLER-JENSEN, KATHRYNreporter.nih.gov
Correlative biomarkers of IL-6 blockade combined with checkpoint inhibitionNIHNational Cancer Institute2021 to 2024$2,320,161July 2, 2020June 30, 2025MEHNERT, JANICE M.reporter.nih.gov
Regulating Gli Function in Hair Follicle ProgenitorsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,320,049May 7, 2007December 31, 2027ORO, ANTHONY Ereporter.nih.gov
A personalized approach to skin cancer prevention among adolescentsNIHNational Cancer Institute2021 to 2024$2,317,171March 1, 2020February 28, 2026WU, YELENA PINGreporter.nih.gov
Functional and Therapeutic Significance of PLK4 in MelanomaNIHNational Cancer Institute2022 to 2025$2,316,913July 25, 2022June 30, 2027AHMAD, NIHALreporter.nih.gov
Role of Desmoglein 1 in Keratinocyte-Melanocyte Communication and MelanomaNIHNational Cancer Institute2021 to 2025$2,314,190February 1, 2019February 28, 2029GREEN, KATHLEEN JANEEreporter.nih.gov
Identification and assessment of unconventional tumor-associated antigens as potential targets for cytotoxic T-cell based immunotherapy of cancerNIHNational Cancer Institute2022 to 2025$2,299,787July 1, 2022June 30, 2027LIZEE, GREGORY Areporter.nih.gov
The regulation of melanocyte stem cells by Wnt signalingNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,297,460August 5, 2011July 31, 2026ITO, MAYUMIreporter.nih.gov
Cell type-directed Tim-3 targeting in melanomaNIHNational Cancer Institute2022 to 2025$2,295,658June 1, 2022May 31, 2027BARTHEL, STEVEN RUSSELLreporter.nih.gov
Characterizing and predicting colitis in immune checkpoint blockade-treated cancer patientsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,286,893June 1, 2020May 31, 2026GNJATIC, SACHAreporter.nih.gov
Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,285,106December 8, 2021November 30, 2025SERGIENKO, EDUARD A.reporter.nih.gov
Identification and characterization of cancer cell states by novel computational and experimental technologies - Resubmission - 1NIHNational Cancer Institute2022 to 2025$2,279,461June 21, 2022May 31, 2027YANAI, ITAIreporter.nih.gov
Chromosome 1q ceRNAs in Melanoma Progression and MetastasisNIHNational Cancer Institute2021 to 2025$2,273,687May 1, 2021April 30, 2027KARRETH, FLORIANreporter.nih.gov
Androgen receptor signaling and sex differences in anti-tumor dendritic cell functionNIHNational Cancer Institute2025$2,265,578September 23, 2025August 31, 2029RUHLAND, MEGAN Kreporter.nih.gov
The Aging Cutaneous Microenvironment and Cancer InitiationNIHNational Institute on Aging2021 to 2025$2,262,646September 30, 2021May 31, 2026FISHER, GARY Jreporter.nih.gov
Development of selective HDAC6 inhibitors to improve cancer immunotherapyNIHNational Cancer Institute2022 to 2025$2,260,714February 1, 2021January 31, 2026VILLAGRA, ALEJANDRO Vreporter.nih.gov
Androgen receptor function in melanomaNIHNational Cancer Institute2022 to 2025$2,253,887September 23, 2022August 31, 2027DOTTO, GIAN-PAOLOreporter.nih.gov
Small-molecule exploitation of ZBP1-driven nuclear necroptosis for cancer immunotherapyNIHNational Cancer Institute2023 to 2025$2,239,005January 1, 2023December 31, 2027BALACHANDRAN, SIDDHARTHreporter.nih.gov
Post-translational SOX2 modification - a regulatory switch between self-renewal and differentiation in squamous cell carcinomaNIHNational Cancer Institute2021 to 2025$2,223,749December 1, 2020November 30, 2025SCHOBER, MARKUSreporter.nih.gov
A Platform Technology to Genetically Reprogram Cancer Cells for Enhanced ImmunotherapyNIHNational Cancer Institute2021 to 2025$2,221,249July 1, 2025June 30, 2027TZENG, STEPHANY YIreporter.nih.gov
Mechanisms of liver metastasis and associated resistance to immunotherapyNIHNational Cancer Institute2021 to 2025$2,220,950March 9, 2021February 28, 2026IZAR, BENJAMINreporter.nih.gov
Skin cancer on social media: Analyzing current communications, modeling diffusion potential, and developing innovative prevention-focused messagesNIHNational Cancer Institute2024 to 2025$2,164,376September 3, 2024August 31, 2028WALSH-BUHI, ERIC RICHARDreporter.nih.gov
Role of circular RNA CDR1as in melanomaNIHNational Cancer Institute2021 to 2024$2,159,990March 2, 2020February 28, 2025HERNANDO, EVAreporter.nih.gov
Role of S.aureus in Cutaneous T Cell Lymphoma PathogenesisNIHNational Cancer Institute2022 to 2025$2,150,022May 10, 2022April 30, 2027KORALOV, SERGEI BORISOVICHreporter.nih.gov
Cell adhesion and tissue dynamics in the skinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$2,136,170December 1, 1980August 31, 2028FUCHS, ELAINEreporter.nih.gov
Sustaining Tissue Resident Memory T cellsNIHNational Cancer Institute2022 to 2025$2,112,390January 1, 2022December 31, 2026HUANG, YINA HSINGreporter.nih.gov
Coordinated Cytoskeletal Dynamics and Membrane Remodeling in Cellular Shape ChangeNIHNational Institute of General Medical Sciences2021 to 2025$2,110,101December 1, 2019November 30, 2029GUPTON, STEPHANIEreporter.nih.gov
Using dietary glutamine supplementation for melanoma prevention and targeted therapyNIHNational Cancer Institute2021 to 2025$2,095,124July 1, 2021June 30, 2027KONG, MEIreporter.nih.gov
Multimodal confocal microscopy for surgical guidance of skin resectionsNIHNational Cancer Institute2022 to 2025$2,090,817August 1, 2022July 31, 2027TUNNELL, JAMES Wreporter.nih.gov
Clinical evaluation of a novel AKT/PDK1 inhibitor, PHT-427, for the treatment of multi-field actinitc keratosesNIHNational Cancer Institute2025$2,085,765September 15, 2025August 31, 2027POWIS, GARTHreporter.nih.gov
Genome-wide analysis of the formation and mutagenesis of atypical UV photoproducts in skin cancerNIHNational Institute of Environmental Health Sciences2021 to 2025$2,084,325April 1, 2021June 19, 2026WYRICK, JOHN Jreporter.nih.gov
Mitochondrial lateral transfer during metastasisNIHNational Cancer Institute2021 to 2025$2,081,728February 1, 2021January 31, 2026ROH, MINNAreporter.nih.gov
Multi-cellular interactions defining the human brain metastatic nicheNIHNational Cancer Institute2023 to 2025$2,058,782May 1, 2023April 30, 2028IZAR, BENJAMINreporter.nih.gov
Cell fate decisions in Merkel cell carcinoma initiation and maintenanceNIHNational Cancer Institute2021 to 2024$2,054,205February 20, 2020January 31, 2025DLUGOSZ, ANDRZEJ A.reporter.nih.gov
Innovative Research for Cancer Nanotechnology (IRCN) for Enhancing Melanoma-specific Immune Responses by the Rational Design of Spherical Nucleic AcidsNIHNational Cancer Institute2022 to 2025$2,035,485March 14, 2022February 28, 2027MIRKIN, CHAD A.reporter.nih.gov
Advanced Surgical Pathology DeviceNIHNational Cancer Institute2023 to 2024$2,027,951August 1, 2019April 30, 2026GAREAU, DANIEL SUMMERreporter.nih.gov
Mutational Signatures of a Combined Environmental Exposure: Arsenic and Ultraviolet RadiationNIHNational Institute of Environmental Health Sciences2021 to 2024$2,018,372April 6, 2020January 31, 2026HUDSON, LAURIE Greporter.nih.gov
Defining epigenetic regulators of tumor heterogeneity and metastasis in melanomaNIHNational Cancer Institute2022 to 2025$2,015,559July 5, 2022June 30, 2027HERNANDO, EVAreporter.nih.gov
The role of the CD58:CD2 axis in cancer immune evasion and resistance to immunotherapyNIHNational Cancer Institute2022 to 2025$2,007,768September 1, 2022August 31, 2027FRANGIEH, CHRISTOPHERreporter.nih.gov
A Convergent Node in Melanoma to Block Multiple Oncogenic Pathways SimultaneouslyNIHNational Cancer Institute2021 to 2024$2,007,018July 1, 2020June 30, 2025KWONG, LAWRENCEreporter.nih.gov
Targeting the vasculature to enhance anti-tumor immunityNIHNational Cancer Institute2021 to 2025$2,001,230September 1, 2014June 30, 2030DUDLEY, ANDREW CARLreporter.nih.gov
A Phase 2, randomized, double-blind, 4-arm, multicenter study to demonstrate the efficacy and safety of topical dosage formulations of a prescription drug product for actinic keratosisNIHNational Cancer Institute2023 to 2024$2,000,000September 14, 2023August 31, 2025ISAACMAN, STEVENreporter.nih.gov
Programming Metabolically Fit TILs for ImmunotherapyNIHNational Cancer Institute2023 to 2024$2,000,000February 15, 2020August 31, 2025MEHROTRA, SHIKHARreporter.nih.gov
Immunotherapy to deplete key Treg subsets in solid tumorsNIHNational Cancer Institute2024 to 2025$2,000,000August 13, 2024July 31, 2027SUZDAK, PETER DAVIDreporter.nih.gov
Noninvasive prediction of skin precancer severity using in vivo cellular imaging and deep learning algorithms.NIHNational Cancer Institute2023 to 2024$1,999,298July 1, 2023May 31, 2025SANCHEZ, GABRIEL NESTORreporter.nih.gov
Regulation of stem-like CD8+ T cells and their role in immunotherapyNIHNational Cancer Institute2021 to 2025$1,999,210March 1, 2015April 30, 2027ANDERSON, ANA Creporter.nih.gov
7HP349, an Integrin Activator to Treat Patients With anti-PD-1 Resistant Solid TumorsNIHNational Cancer Institute2023 to 2024$1,998,400September 19, 2023August 31, 2025MARATHI, UPENDRAreporter.nih.gov
Regulation of the ERK signaling pathway by K63-linked polyubiquitinationNIHNational Cancer Institute2022 to 2025$1,994,802September 9, 2022August 31, 2027YANG, XIAOLUreporter.nih.gov
Re-engineering differential regulation of ferroptosis in melanoma microenvironmentNIHNational Cancer Institute2023 to 2025$1,975,612July 12, 2023June 30, 2028BUNIMOVICH, YURIreporter.nih.gov
Gasdermin E and pyroptosis in cancerNIHNational Cancer Institute2021 to 2024$1,970,899April 3, 2020March 31, 2025LIEBERMAN, JUDYreporter.nih.gov
Defining the role of innate immune cells in the early stages of immune surveillance of skin cancer by using a novel model that allows in vivo imaging of the immunoediting process.NIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,968,500September 15, 2022August 31, 2027ROOP, DENNISreporter.nih.gov
Translation of commensal bacteria mechanism for immunotherapyNIHNational Cancer Institute2021 to 2024$1,965,036December 2, 2019November 30, 2024HANG, HOWARD Creporter.nih.gov
Dual-isotope SPECT imaging and immunophenotyping of immune cells to determine response to immunotherapyNIHNational Cancer Institute2023 to 2025$1,963,130February 7, 2023January 31, 2028KLUGER, HARRIET M.reporter.nih.gov
Identifying Therapeutic Targets for Stage III MelanomaNIHNational Cancer Institute2021 to 2024$1,959,905December 4, 2019November 30, 2025GANESAN, ANAND Kreporter.nih.gov
NGF recruits nerve fibers to reprogram an immunosuppressive microenvironment in melanomaNIHNational Cancer Institute2021 to 2024$1,945,149February 1, 2020January 31, 2025WANG, XIAO-FANreporter.nih.gov
Exploiting a novel regulator of immunometabolism to enhance immunotherapyNIHNational Cancer Institute2022 to 2025$1,939,594July 1, 2022June 30, 2027USHERWOOD, EDWARD Jreporter.nih.gov
Chronic Mitochondrial Division and Melanoma: Mechanism, Prognosis, and TherapyNIHNational Cancer Institute2022 to 2025$1,935,169July 15, 2022May 31, 2027CHIPUK, JERRY EDWARDreporter.nih.gov
Infrared Skin Imaging to Transform Noninvasive Diagnosis and Management of Skin DiseaseNIHOffice of the Director, National Institutes of Health2021 to 2025$1,933,675September 14, 2021August 31, 2026SHMUYLOVICH, LEONIDreporter.nih.gov
Defining and targeting epigenetic plasticity-driven drug resistance and immune escape in melanomaNIHNational Cancer Institute2022 to 2025$1,926,244July 15, 2022June 30, 2027SMALLEY, KEIRANreporter.nih.gov
The impact of the dermal ECM microenvironment on cutaneous aging and cancerNIHNational Institute on Aging2023 to 2025$1,925,573March 15, 2023February 28, 2028FISHER, GARY Jreporter.nih.gov
Therapeutic strategies for treatment of giant congenital melanocytic neviNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,921,106August 1, 2017July 31, 2028FISHER, DAVID Ereporter.nih.gov
Role of Heat Shock Protein 70 as a Mediator and Therapeutic Target in T-cell LymphomasNIHNational Cancer Institute2022 to 2025$1,917,273July 20, 2022June 30, 2027ORLOWSKI, ROBERT ZYGMUNTreporter.nih.gov
Mechanisms of Lymphomagenesis of Skin Resident Gamma Delta T cellsNIHNational Cancer Institute2022 to 2025$1,898,706December 13, 2021November 30, 2026LE POOLE, I. CAROLINEreporter.nih.gov
Roles and regulation of transcriptional reprogramming in squamous carcinogenesisNIHNational Cancer Institute2022 to 2025$1,892,832August 1, 2022July 31, 2027SCHOBER, MARKUSreporter.nih.gov
Improvement of cellular immunotherapy during dysbiosis- ResubmissionNIHNational Cancer Institute2021 to 2025$1,891,918September 15, 2021August 31, 2026DINGS, RUUD P.M.reporter.nih.gov
Preventing MAPK inhibitor resistance in melanoma by targeting genomic instability and immune resistanceNIHNational Cancer Institute2021 to 2025$1,884,180September 4, 2013June 30, 2026LO, ROGER Sreporter.nih.gov
Melanoma: Metabolic Biomarkers of Response to Targeted TherapyNIHNational Cancer Institute2021 to 2024$1,875,811March 1, 2020February 28, 2026NATH, KAVINDRAreporter.nih.gov
Innate NLRC4 signaling controls adaptive immune responsesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,874,689June 20, 2023May 31, 2028SUTTERWALA, FAYYAZ S.reporter.nih.gov
GCDH Addiction in MelanomaNIHNational Cancer Institute2022 to 2024$1,859,149July 1, 2022September 30, 2024RONAI, ZEEV A.reporter.nih.gov
A digital intervention to improve skin self-examination among melanoma survivorsNIHNational Cancer Institute2023 to 2025$1,854,574April 1, 2022March 31, 2027MANNE, SHARON Lreporter.nih.gov
Mechanism for arsenic induced carcinogenesisNIHNational Institute of Environmental Health Sciences2021 to 2025$1,853,908August 1, 2017November 30, 2028STATES, J CHRISTOPHERreporter.nih.gov
Rewired Signaling at the Nexus of Melanoma Metastasis and ResistanceNIHNational Cancer Institute2024 to 2025$1,828,436August 1, 2024July 31, 2031RONAI, ZEEV A.reporter.nih.gov
Nevus associated microRNAs as mediators of BRAF-induced growth arrest and biomarkers of melanoma progressionNIHNational Cancer Institute2021 to 2025$1,826,736August 24, 2021July 31, 2026JUDSON-TORRES, ROBERT LAIRDreporter.nih.gov
Tumor-derived extracellular vesicles in the pre-metastatic niche.NIHNational Cancer Institute2021 to 2025$1,821,912August 1, 2017August 31, 2029DECLERCK, YVES Areporter.nih.gov
Metastatic Clonal Heterogeneity and its Impact on Melanoma Therapeutic ResistanceNIHNational Cancer Institute2021 to 2024$1,819,435May 1, 2020April 30, 2026HUGO, WILLYreporter.nih.gov
Dissecting the role of hypoxia in T cell differentiation in cancerNIHNational Cancer Institute2023 to 2025$1,812,664January 1, 2023December 31, 2027DELGOFFE, GREG M.reporter.nih.gov
Senescence-on-a-chip: Building a microphysiological 3D skin modelNIHNational Cancer Institute2024 to 2025$1,809,500August 5, 2022July 31, 2026CHRISTIANO, ANGELA Mreporter.nih.gov
Applying pathomics to establish a biosignature for aggressive skin melanomaNIHNational Cancer Institute2022 to 2025$1,808,280May 1, 2021April 30, 2027SAENGER, YVONNE MARGARETreporter.nih.gov
Optimization of a personalized skin cancer risk intervention for at-risk young adultsNIHNational Cancer Institute2023 to 2025$1,806,355April 1, 2023March 31, 2028WU, YELENA PINGreporter.nih.gov
Development of Potent and non-toxic rexinoids to prevent non-melanoma skin cancerNIHNational Cancer Institute2023 to 2025$1,799,831March 7, 2023February 29, 2028ATIGADDA, VENKATRAM REDDYreporter.nih.gov
Reprogramming of the stromal microenvironment in melanoma progression and therapeutic escapeNIHNational Cancer Institute2021 to 2025$1,797,224June 15, 2021May 31, 2027ZHANG, YUHANGreporter.nih.gov
The role of And-1 in nucleotide excision repairNIHNational Cancer Institute2022 to 2025$1,791,325February 17, 2022January 31, 2027ZHU, WENGEreporter.nih.gov
VLA-4–targeted 67Cu-LLP2A preconditioning enhances efficacy of T-cell-based adoptive immunotherapyNIHNational Cancer Institute2023 to 2025$1,788,311July 5, 2023June 30, 2028PATEL, RAVI BHASKERreporter.nih.gov
Twist1 as a Target for Prevention and Treatment of Cutaneous Squamous Cell CarcinomaNIHNational Cancer Institute2021 to 2025$1,780,213July 1, 2021December 31, 2026DIGIOVANNI, JOHNreporter.nih.gov
The Oncogene Activated Mitochondrial Unfolded Protein Response Regulates Senescence BiologyNIHNational Cancer Institute2023 to 2025$1,778,295April 3, 2023March 31, 2028CHIPUK, JERRY EDWARDreporter.nih.gov
Regulation of epidermal growth and differentiation through mRNA exportNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,760,596August 2, 2022May 31, 2027SEN, GEORGE Lreporter.nih.gov
Allosteric inhibitors targeting oncogenic BRAF V600E dimersNIHNational Cancer Institute2021 to 2024$1,760,127December 1, 2019November 30, 2024GAVATHIOTIS, EVRIPIDISreporter.nih.gov
PyroTIMER Technology: Enabling T-Cell Persistence in Immunosuppressive Tumor MicroenvironmentsNIHNational Cancer Institute2024 to 2025$1,747,620September 23, 2024August 31, 2026BAGATI, ARCHISreporter.nih.gov
Therapy with fecal microbiota transplantation and immune checkpoint blockade for solid tumorsNIHNational Cancer Institute2022 to 2025$1,735,364June 16, 2022May 31, 2027ZAROUR, HASSANE Mreporter.nih.gov
Mechanisms of BAP1 activity in human cancer developmentNIHNational Cancer Institute2021 to 2024$1,733,898December 13, 2019November 30, 2025CARBONE, MICHELEreporter.nih.gov
Image Deeper with Synthetic Waves: A Novel Non-Invasive Optical Approach for Skin Lesion Assessment at Multiple ScalesNIHNational Institute on Drug Abuse2025$1,732,297September 1, 2025August 31, 2027WILLOMITZER, FLORIANreporter.nih.gov
Ablating Liver Metastases with SBRT to Enhance Immune Checkpoint Blockade in MelanomaNIHNational Cancer Institute2023 to 2025$1,722,266May 5, 2023April 30, 2028LAWRENCE, THEODORE Sreporter.nih.gov
The genomic landscape and evolution of cutaneous squamous cell carcinomaNIHNational Cancer Institute2022 to 2025$1,707,881September 22, 2022August 31, 2027SHAIN, ALAN HUNTERreporter.nih.gov
Unraveling the regulatory circuits that drive Merkel cell carcinomaNIHNational Cancer Institute2021 to 2025$1,699,585August 10, 2021July 31, 2027PADI, MEGHAreporter.nih.gov
Epigenetic enhancer control in maintaining homeostasis and preventing carcinogenesis in the epidermisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,689,356July 15, 2020June 30, 2025CAPELL, BRIANreporter.nih.gov
Immune Therapy for Brain MetastasisNIHNational Cancer Institute2023 to 2025$1,683,722April 18, 2023March 31, 2028JILAVEANU, LUCIA BEATRICEreporter.nih.gov
Combining senescence-inducing and senolytic agents to improve melanoma therapyNIHNational Cancer Institute2021 to 2025$1,682,618December 1, 2023November 30, 2025VILGELM, ANNA Ereporter.nih.gov
Optimizing pre-analytic sample handling for high throughput TCR sequencing in cutaneous T cell lymphomaNIHNational Cancer Institute2021 to 2024$1,669,583September 1, 2020May 31, 2026CLARK, RACHAEL ANNreporter.nih.gov
The integrated stress response and the microenvironment in melanoma progressionNIHNational Cancer Institute2022 to 2025$1,645,104January 1, 2022December 31, 2026KOUMENIS, CONSTANTINOSreporter.nih.gov
Two photon fluorescence microscopy for dermatologic surgery and biopsyNIHNational Cancer Institute2021 to 2025$1,638,998April 1, 2021March 31, 2026GIACOMELLI, MICHAEL GENEreporter.nih.gov
Circadian clock disruption: A risk factor for environmental carcinogenesisNIHNational Institute of Environmental Health Sciences2021 to 2025$1,629,351August 28, 2020October 31, 2026GADDAMEEDHI, SHOBHANreporter.nih.gov
Therapeutically harnessing anti-viral resident memory T cells in solid tumorsNIHNational Cancer Institute2023 to 2025$1,618,880January 1, 2023December 31, 2027ROSATO, PAMELAreporter.nih.gov
Mechanisms of UV-Mediated Melanoma DevelopmentNIHNational Cancer Institute2021 to 2024$1,616,093September 4, 2020May 31, 2026BURD, CHRISTIN Ereporter.nih.gov
Developing new therapeutic strategies for brain metastasisNIHNational Cancer Institute2023 to 2025$1,609,412February 1, 2023January 31, 2028HERNANDO, EVAreporter.nih.gov
UCHL5 as a regulator and therapeutic target in metastatic melanomaNIHNational Cancer Institute2021 to 2024$1,608,800August 1, 2020April 30, 2026RAI, KUNALreporter.nih.gov
Lipid programs in melanocyte transformationNIHNational Cancer Institute2021 to 2025$1,606,364March 1, 2020February 28, 2026OVERHOLTZER, MICHAEL H.reporter.nih.gov
Understanding PPARgamma signaling in melanoma brain metastasisNIHNational Cancer Institute2021 to 2024$1,602,434December 1, 2019October 31, 2024CHEN, QINGreporter.nih.gov
Novel TYRO3 inhibitors for treatment of cancerNIHNational Cancer Institute2021 to 2025$1,600,201April 1, 2021March 31, 2027WANG, XIAODONGreporter.nih.gov
Signaling importance of ‘functionless’ lyso-PAF, an inactive form of platelet activating factor, in melanoma with mutant NrasNIHNational Cancer Institute2022 to 2025$1,590,243February 23, 2010January 31, 2027CHEN, JINGreporter.nih.gov
Metabolic and epigenetic dependencies in melanomas during metastasis and targeted-drug resistanceNIHNational Cancer Institute2021 to 2024$1,582,220July 1, 2014March 31, 2026PUIGSERVER, PEREreporter.nih.gov
Structural and Functional Characterization of RhoGEF Regulation Using Nanodiscs to Assemble Membrane-associated Signaling ScaffoldsNIHNational Institute of General Medical Sciences2022 to 2025$1,577,420August 1, 2022June 30, 2027CASH, JENNIFER NICOLEreporter.nih.gov
Epiproteomics of Sezary SyndromeNIHNational Cancer Institute2022 to 2024$1,560,839June 1, 2020May 31, 2026ELENITOBA-JOHNSON, KOJO S. J.reporter.nih.gov
Novel Methods for Identifying Genetic Interactions for Cancer PrognosisNIHNational Cancer Institute2021 to 2024$1,555,447July 1, 2016June 30, 2025MA, SHUANGGEreporter.nih.gov
A High-Throughput Model for Human MelanomaNIHNational Cancer Institute2021 to 2025$1,553,468April 13, 2007June 30, 2026HOLMEN, SHERI Lreporter.nih.gov
The role of regulation and subcellular localization of GTP biosynthesis in melanoma invasion and metastasisNIHNational Cancer Institute2023 to 2025$1,534,928August 30, 2023July 31, 2028NIKIFOROV, MIKHAILreporter.nih.gov
Eradication of Escaped Variant Tumor Cells for Cancer ImmunotherapyNIHNational Cancer Institute2022 to 2025$1,533,120January 1, 2021August 31, 2026LU, YONGreporter.nih.gov
Novel focused ultrasound enhanced calreticulin-nanoparticle for immune primed melanoma immunotherapyNIHNational Cancer Institute2023 to 2025$1,525,979June 4, 2019July 31, 2027RANJAN, ASHISHreporter.nih.gov
Identifying novel therapies targeting Merkel cell carcinoma and tumor microenvironmentNIHNational Cancer Institute2022 to 2025$1,511,555July 14, 2022June 30, 2027GAO, LINGreporter.nih.gov
Exploiting the distinct genomics and signaling of colorectal cancers to effectively target ERKNIHNational Cancer Institute2021 to 2024$1,502,540December 10, 2018November 30, 2024YAEGER, RONAreporter.nih.gov
Therapeutic Mechanism of CD47 Blockade in Suppressing Melanoma MetastasisNIHNational Cancer Institute2021 to 2025$1,501,311April 20, 2020March 31, 2026BOIKO, ALEXANDER Dreporter.nih.gov
Regulation of interferon signaling in melanoma by the cohesin complex protein STAG2 via 3D genome organizationNIHNational Cancer Institute2023 to 2025$1,501,310September 1, 2022August 31, 2027ZHENG, BINreporter.nih.gov
Merkel cell polyomavirus infection, host response, and viral oncogenic mechanismNIHNational Cancer Institute2022 to 2025$1,497,331April 1, 2015November 30, 2026YOU, JIANXINreporter.nih.gov
Role of AMPK in melanoma brain metastasisNIHNational Cancer Institute2023 to 2025$1,497,263January 1, 2023December 31, 2027ZHENG, BINreporter.nih.gov
New Strategies for Treatment of NRAS Mutant Melanoma after Progression on Immune Checkpoint InhibitorsNIHNational Cancer Institute2021 to 2024$1,494,321August 19, 2005September 30, 2025RICHMOND, ANNreporter.nih.gov
Applying Genomic Dosimeters of UV Damage to Predicting Skin Cancer RiskNIHNational Institute of Environmental Health Sciences2021 to 2024$1,494,169May 15, 2019February 28, 2026BRASH, DOUGLAS Ereporter.nih.gov
Characterizing oncogenic function of ITCH in melanomaNIHNational Cancer Institute2021 to 2025$1,491,935August 1, 2021July 31, 2027WAN, LIXINreporter.nih.gov
Role of Perivascular Mesenchymal Stem Cells (pMSCs) in the Bone Marrow Niche and the Extracellular Matrix in the Control of Skeletal MetastasisNIHNational Cancer Institute2021 to 2025$1,487,614September 1, 2020May 31, 2026SOMOZA, RODRIGO ALFONSOreporter.nih.gov
Investigating the PD-L1:NLRP3 signaling axis as a tumor intrinsic mechanism of adaptive resistance to anti-PD-1 antibody immunotherapyNIHNational Cancer Institute2021 to 2024$1,483,568August 1, 2020January 31, 2025HANKS, BRENT ALLENreporter.nih.gov
Role of metabolic crosstalk in determining immunity during tumor progressionNIHNational Cancer Institute2023 to 2025$1,477,010July 14, 2023June 30, 2028ANDERSON, ANA Creporter.nih.gov
Linking Genetic, Epigenetic and Signaling Mechanisms of Oncogene AddictionNIHNational Cancer Institute2021 to 2025$1,474,583May 1, 2021April 30, 2027FALLAHI-SICHANI, MOHAMMADreporter.nih.gov
Tissue Damage-Driven Squamous Cell CarcinomaNIHNational Cancer Institute2021 to 2025$1,470,745January 1, 2021January 30, 2025SOUTH, ANDREWreporter.nih.gov
KLF-mediated coordination of signaling and epigenetic mechanisms in the skinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,465,497February 1, 2020January 31, 2026MILLAR, SARAH E.reporter.nih.gov
Molecular Mechanisms Underlying the Prevention of BCC ResistanceNIHNational Institute of Environmental Health Sciences2021 to 2024$1,458,000April 7, 2020January 31, 2025BICKERS, DAVID RINSEYreporter.nih.gov
Mechanism For Merkel Cell Polyomavirus PersistenceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,453,906January 10, 2024November 30, 2028CHANG, YUANreporter.nih.gov
Targeted therapies in cutaneous melanomaNIHNational Cancer Institute2021 to 2024$1,448,655July 14, 2014May 31, 2026APLIN, ANDREW ERICreporter.nih.gov
Study of Anti-Tumor Immunity and Tissue Resident Memory Cell Development by NKG2D and Ribosomal Protein S6 Signaling in T cellsNIHNational Cancer Institute2021 to 2024$1,441,104July 14, 2021February 28, 2025GUEVARA-PATINO, JOSE ALEJANDROreporter.nih.gov
Merkel cell polyomavirus HLA class I epitopes for generating therapeutic T cell-based cancer immunotherapyNIHNational Cancer Institute2024 to 2025$1,438,870January 9, 2024December 31, 2028KESKIN, DERIN Breporter.nih.gov
Adhesive regulation during cell migrationNIHNational Cancer Institute2022 to 2025$1,432,752June 10, 2000November 30, 2026HUTTENLOCHER, ANNAreporter.nih.gov
Expanding the Therapeutic Window of Nanoparticle STING Agonists for Cancer ImmunotherapyNIHNational Cancer Institute2021 to 2025$1,430,039August 21, 2020April 30, 2027WILSON, JOHN TANNERreporter.nih.gov
Role of lipid metabolism in CD8+ T cell ferroptosisNIHNational Cancer Institute2023 to 2025$1,429,382September 19, 2023August 31, 2028YI, QINGreporter.nih.gov
Mechanisms of cancer mutationsNIHNational Cancer Institute2023 to 2025$1,423,519December 1, 2022November 30, 2027PFEIFER, GERD Preporter.nih.gov
Regulation of Human Tumorigensis by Cancer Specific NXF1 Adaptor ProteinsNIHNational Cancer Institute2022 to 2025$1,420,402April 1, 2022March 31, 2027SEN, GEORGE Lreporter.nih.gov
Role and mechanisms of IGF2BP1 in melanoma pathogenesisNIHNational Cancer Institute2021 to 2024$1,416,035December 2, 2019November 30, 2024SPIEGELMAN, VLADIMIR S.reporter.nih.gov
ISIC-REPO; ISIC Skin Imaging Repository Enhancements for Promoting Interoperability and UtilizationNIHNational Cancer Institute2024 to 2025$1,411,293April 1, 2024March 31, 2029HALPERN, ALLAN Creporter.nih.gov
The Role of CD5 in Tumor ImmunityNIHNational Cancer Institute2021 to 2024$1,408,701July 1, 2020June 30, 2025KLECHEVSKY, EYNAV YAFITreporter.nih.gov
The CD93 pathway and melanoma therapyNIHNational Cancer Institute2022 to 2025$1,397,926December 3, 2021November 30, 2026ZHU, YUWENreporter.nih.gov
Estrogen receptor beta is a targetable melanoma tumor suppressorNIHNational Cancer Institute2022 to 2025$1,391,719December 1, 2021November 30, 2026BURD, CRAIG Jreporter.nih.gov
Investigating p16 Loss in Pro-tumorigenic MetabolismNIHNational Cancer Institute2021 to 2024$1,388,821April 1, 2020March 31, 2026AIRD, KATHERINE MARIEreporter.nih.gov
Targeting the tumor microenvironment with engineered CD4+ T cellsNIHNational Cancer Institute2024 to 2025$1,387,760August 8, 2024July 31, 2029VEATCH, JOSHUA Rreporter.nih.gov
The Role of Genetic Risk Factors in Keratinocyte Carcinoma SusceptibilityNIHNational Cancer Institute2021 to 2025$1,387,132March 1, 2020December 31, 2026CHOQUET, HELENEreporter.nih.gov
A hybrid effectiveness-implementation trial to integrate precision skin cancer risk feedback in federally qualified health centersNIHNational Cancer Institute2024 to 2025$1,381,782September 1, 2024August 31, 2029KANETSKY, PETER Areporter.nih.gov
Determinants of toxicity and response to immune checkpoint blockade through integrative profiling of T cell clonal dynamics and plasma cell- free DNANIHNational Cancer Institute2024 to 2025$1,377,117June 7, 2024May 31, 2026CHAUDHURI, AADELreporter.nih.gov
Novel cell therapy approaches for molecularly defined subsets of therapy-resistant melanomaNIHNational Cancer Institute2023 to 2025$1,375,717September 21, 2023August 31, 2028KLEBANOFF, CHRISTOPHER AUSTINreporter.nih.gov
Wounding Therapy and PhotocarcinogenesisNIHNational Institute on Aging2022 to 2024$1,372,342September 1, 2014August 31, 2027TRAVERS, JEFFREY B.reporter.nih.gov
Targeting Rheostatic Mechanisms of Melanoma ProgressionNIHNational Cancer Institute2021 to 2024$1,370,957July 1, 2020June 30, 2025GROSSMANN, ALLIE H.reporter.nih.gov
Expanding the tumor antigen landscape and maintaining APCs in a T cell-activating state to restore tumor immunityNIHNational Cancer Institute2023 to 2025$1,370,839May 3, 2023April 30, 2028DAVILA, EDUARDO Vreporter.nih.gov
Identification of Covalent Transcriptional Dependencies in MelanomaNIHNational Cancer Institute2024 to 2025$1,368,465June 14, 2024May 31, 2029BAR-PELED, LIRONreporter.nih.gov
Immunogenetic determinants of cancer riskNIHNational Cancer Institute2024 to 2025$1,357,514June 1, 2024May 31, 2029SAMSTEIN, ROBERT Mreporter.nih.gov
Prebiotic diet intervention to enhance the microbiome and immunotherapy response in melanomaNIHNational Cancer Institute2024 to 2025$1,354,877August 15, 2024July 31, 2029DANIEL-MACDOUGALL, CARRIEreporter.nih.gov
A network approach to interrogate cellular plasticity and drug resistance in cancerNIHNational Cancer Institute2024 to 2025$1,350,826June 15, 2024May 31, 2026AKHURST, ROSEMARY Jreporter.nih.gov
Rewiring T cell exhaustion with immune checkpoint blockade therapyNIHNational Cancer Institute2024 to 2025$1,349,992August 7, 2024July 31, 2029BRADLEY, LINDA MAC PHERSONreporter.nih.gov
Regulation of DNA Excision Repair in ChromatinNIHNational Institute of Environmental Health Sciences2021 to 2025$1,347,804August 1, 2018March 31, 2029WYRICK, JOHN Jreporter.nih.gov
Proteolysis targeting chimera against nuclear receptor NR4A1 for melanoma therapyNIHNational Cancer Institute2024 to 2025$1,334,046April 15, 2024March 31, 2029ZHANG, WEIZHOUreporter.nih.gov
The Role of Schwann Cells in the Progression of MelanomaNIHNational Cancer Institute2023 to 2025$1,322,543January 1, 2023December 31, 2027BUNIMOVICH, YURIreporter.nih.gov
Interplay of natural killer cells and extracellular matrix proteins in solid cancersNIHNational Cancer Institute2024 to 2025$1,321,974April 1, 2024March 31, 2029DEMEHRI, SHADMEHRreporter.nih.gov
Designer extracellular vesicles for cancer therapyNIHNational Cancer Institute2024 to 2025$1,308,672July 8, 2024June 30, 2028XU, XIAOWEIreporter.nih.gov
Melanoma Resistance Evolution Atlas (MREA) for identifying combinatorial targets to prevent and reverse MAPKi resistanceNIHNational Cancer Institute2024 to 2025$1,307,905March 1, 2024February 28, 2029LO, ROGER Sreporter.nih.gov
Targeting aberrant anti-apoptotic signaling for prevention of skin cancerNIHNational Cancer Institute2021 to 2024$1,301,371August 1, 2020April 30, 2026HANSEN, LAURA Areporter.nih.gov
Mechanisms of Smoothened Activation in Hedgehog SignalingNIHNational Institute of General Medical Sciences2022 to 2025$1,292,303February 1, 2022November 30, 2025MANGLIK, AASHISHreporter.nih.gov
Role of the tumor NLRP3 inflammasome in the generation of anti-PD-1 antibody immunotherapy-associated toxicitiesNIHNational Cancer Institute2021 to 2024$1,290,653July 20, 2021January 31, 2025HANKS, BRENT ALLENreporter.nih.gov
Focal Adhesion Kinase - Tumor Biology and TherapeuticsNIHNational Cancer Institute2022 to 2025$1,289,832September 30, 1996January 31, 2027MARLOWE, TIMOTHY Areporter.nih.gov
Sustaining antitumor effector CD8+ T cells for cancer therapyNIHNational Cancer Institute2024 to 2025$1,285,561May 17, 2024April 30, 2029ZHANG, BINreporter.nih.gov
Mechanism of action and function of novel secosteroid 20(OH)D3 in the skinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,281,521May 1, 2018January 30, 2030SLOMINSKI, ANDRZEJ Treporter.nih.gov
Molecular mechanisms of allele-specific NRAS signaling and tumorigenesisNIHNational Cancer Institute2024 to 2025$1,277,886July 1, 2024June 30, 2026BURD, CHRISTIN Ereporter.nih.gov
Melanocyte PDL1 control of UVB-induced IFN-INIHNational Cancer Institute2024 to 2025$1,271,892July 8, 2024June 30, 2029CURIEL, TYLER J.reporter.nih.gov
Preventing UV-induced immunosuppression and skin carcinogenesis with R-carvedilolNIHNational Cancer Institute2022 to 2025$1,267,574July 1, 2022June 30, 2027HUANG, YINGreporter.nih.gov
Targeting dsRNA sensing and ADAR1 in melanomaNIHNational Cancer Institute2024 to 2025$1,263,556March 1, 2024February 28, 2029ISHIZUKA, JEFFREY J.reporter.nih.gov
Role of DeltaNp63 alpha and TIP60 in SCC progression and chemoresistanceNIHNational Cancer Institute2024 to 2025$1,261,890December 7, 2023November 30, 2028KADAKIA, MADHAVI Preporter.nih.gov
Integrative Targeted Therapy for MelanomaNIHNational Cancer Institute2024 to 2025$1,240,815April 1, 2024March 31, 2030YANG, JIN-MINGreporter.nih.gov
Combinations of Receptor-Targeted Alpha Radionuclide Therapy and Immune Checkpoint Inhibitors for Melanoma TreatmentNIHNational Cancer Institute2023 to 2025$1,240,605April 1, 2023April 2, 2025MIAO, YUBINreporter.nih.gov
Development of CM-HZ01 as a non-alpha-IL2 therapeutic for the treatment of metastatic melanomaNIHNational Cancer Institute2025$1,228,902January 1, 2025April 30, 2027COOPER, COLLEEN DOYLEreporter.nih.gov
Dissecting the tumor-intrinsic and -extrinsic roles of TBK1 in tumor immunityNIHNational Cancer Institute2023 to 2024$1,226,016August 1, 2023July 31, 2028JENKINS, RUSSELL WILLIAMreporter.nih.gov
The mutational mechanisms shaping melanocytes in human skinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,219,413February 17, 2023November 30, 2027SHAIN, ALAN HUNTERreporter.nih.gov
Bhlhe40 Regulation of T Cell Function During Cancer ImmunotherapyNIHNational Cancer Institute2024 to 2025$1,213,270June 1, 2024May 31, 2026GUBIN, MATTHEW M.reporter.nih.gov
Combating melanoma with an attenuated bacterial therapeuticNIHNational Cancer Institute2023 to 2024$1,212,794May 1, 2023April 30, 2028SONG, JIANXUN JIMreporter.nih.gov
Transcriptional Reprogramming in Melanoma PlasticityNIHNational Cancer Institute2024 to 2025$1,209,297July 18, 2024June 30, 2026LIANG, CHENGYUreporter.nih.gov
Lymph Node-Targeted Codelivery of Albumin-Binding Peptide Antigens and Di-Adjuvant for Melanoma Combination ImmunotherapyNIHNational Cancer Institute2023 to 2025$1,181,605August 1, 2022June 30, 2027ZHU, GUIZHIreporter.nih.gov
Multilevel RCT of Rural Community Sun Safety for Young Children in SportsNIHNational Cancer Institute2024 to 2025$1,170,699May 1, 2024April 30, 2029WU, YELENA PINGreporter.nih.gov
Development and Pre-Clinical Validation of Quantitative Imaging of Cell State Kinetics (QuICK) for Functional Precision OncologyNIHNational Cancer Institute2023 to 2025$1,162,721September 12, 2023August 31, 2028ZANGLE, THOMAS ANDREWreporter.nih.gov
Multivalent Small Circular mRNA Vaccines for Melanoma Combination ImmunotherapyNIHNational Cancer Institute2024 to 2025$1,140,586July 17, 2024June 30, 2029ZHU, GUIZHIreporter.nih.gov
Differential role of different NAD+ kinase Isoforms in melanoma metastasisNIHNational Cancer Institute2022 to 2024$1,136,054May 1, 2022April 30, 2027PISKOUNOVA, ELENAreporter.nih.gov
Regulators of Melanocyte Stem Cell Migration and Melanoma Initiation in Response to Cutaneous UVB IrradiationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,134,507April 1, 2020March 31, 2025WHITE, ANDREW Creporter.nih.gov
Intrinsic and Extrinsic factors regulating competition for active TGFb promote skin memory CD8 T cell fitnessNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$1,132,258July 20, 2024June 30, 2029KAPLAN, DANIEL Hreporter.nih.gov
CCR4-IL2 Bispecific Immunotoxin for Targeted Therapy of Cutaneous T-Cell LymphomaNIHNational Cancer Institute2023 to 2025$1,124,168August 1, 2021January 31, 2027WANG, ZHIRUIreporter.nih.gov
Development of a novel visualization, labeling, and tracking engine for human anatomy.NIHNational Cancer Institute2025$1,116,368August 1, 2025July 31, 2027MOLENDA, MATTHEW ALEXANDERreporter.nih.gov
PRecision IMaging to Evaluate Kaposi Sarcoma (PRIME-KS)NIHNational Cancer Institute2024 to 2025$1,098,683August 7, 2024July 31, 2029ODENY, THOMASreporter.nih.gov
Targeting MCPyV oncogene transcription to suppress tumorigenesisNIHNational Cancer Institute2023 to 2025$1,096,572July 3, 2023June 30, 2028YOU, JIANXINreporter.nih.gov
Dissecting the immunomodulatory effects of NK cells on immune responses to cancerNIHNational Cancer Institute2024 to 2025$1,093,243September 1, 2024August 31, 2029BARRY, KEVIN Creporter.nih.gov
A Multi-Level Investigation of US Indoor Tanning PolicyEnactment, Implementation, Compliance, Impact, and EconomicsNIHNational Cancer Institute2023 to 2024$1,086,870June 1, 2020May 31, 2026HECKMAN, CAROLYNreporter.nih.gov
Cancer Cell-Extrinsic and Intrinsic Regulators of TumorigenesisNIHNational Cancer Institute2021 to 2025$1,085,020September 2, 2021August 31, 2026JI, ANDREWreporter.nih.gov
Label-free digital cytopathology using deep-ultraviolet coded ptychography with intrinsic molecular contrastNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,081,236July 1, 2023June 30, 2027ZHENG, GUOANreporter.nih.gov
Mechanisms of melanoma brain metastasis by CTCs isolated from patients' blood and CSFNIHNational Cancer Institute2021 to 2024$1,054,005December 15, 2017November 30, 2025MARCHETTI, DARIOreporter.nih.gov
The Role of IL-15 in Cutaneous T-cell Lymphoma ProgressionNIHNational Cancer Institute2023 to 2025$1,052,708July 20, 2023June 30, 2028MISHRA, ANJALIreporter.nih.gov
A prognostic mRNA immune signature for resected stage II-III melanomaNIHNational Cancer Institute2022 to 2024$1,050,317June 13, 2019March 31, 2025SAENGER, YVONNE MARGARETreporter.nih.gov
Melanoma Immunotherapy with GPR182 blockadeNIHNational Cancer Institute2023 to 2025$1,049,334January 1, 2023December 31, 2027ZHU, YUWENreporter.nih.gov
The GPR171 pathway in cancer immunotherapyNIHNational Cancer Institute2023 to 2025$1,049,334April 25, 2023March 31, 2028ZHU, YUWENreporter.nih.gov
Targeting the gut microbiome to inhibit melanoma lymph node metastasesNIHNational Cancer Institute2024 to 2025$1,045,724May 1, 2024May 30, 2028WARGO, JENNIFER A.reporter.nih.gov
Ultrasmall particle-based solutions for inducing ferroptosis and improving anti-tumor immune responses in cancerNIHNational Cancer Institute2023 to 2024$1,045,090June 1, 2020May 31, 2026BRADBURY, MICHELLE Sreporter.nih.gov
Skin Cancer Risks and Risk Prediction in Patients with Actinic KeratosisNIHNational Cancer Institute2022 to 2025$1,041,612April 18, 2022March 31, 2027WEHNER, MACKENZIE RACHELreporter.nih.gov
Immunotherapeutic targeting of MIF-dependent chaperone activityNIHNational Cancer Institute2023 to 2025$1,023,531April 1, 2023March 31, 2028MITCHELL, ROBERT Areporter.nih.gov
Analysis of galectin-8 and its ligands in melanoma progressionNIHNational Cancer Institute2024 to 2025$1,014,525May 16, 2024April 30, 2029DIMITROFF, CHARLES Jreporter.nih.gov
Development of LNS8801 for cutaneous melanoma patients who cannot tolerate immunotherapyNIHNational Cancer Institute2025$999,960January 13, 2025December 31, 2026GARYANTES, TINAreporter.nih.gov
IntellipulseTM Platform Technology for Effective Delivery of Therapeutic AgentsNIHNational Cancer Institute2025$984,830September 4, 2025August 31, 2027STRANGE, GARYreporter.nih.gov
Defining the Role of the Cancer Circadian Clock in Tumor Immunity and TumorigenesisNIHNational Cancer Institute2023 to 2025$978,202January 1, 1990November 30, 2026DANG, CHI V.reporter.nih.gov
Rapid 3D POC digital cancer pathology by unique confocal microscopy instrumentation and downstream AI: a simple, efficient, robust direct-to-digital approach to meet market demandNIHNational Cancer Institute2025$978,154June 18, 2025May 31, 2027GAREAU, DANIEL SUMMERreporter.nih.gov
Targeting Unique Meyloid Populations to Overcome Anti-PD-1 Resistance Conferred by Specific Cancer MutationsNIHNational Cancer Institute2021 to 2024$962,495July 1, 2020June 30, 2025MILLER, BRIAN Creporter.nih.gov
Role of histotripsy synergized CD40 signaling in the re-engineering of cold tumorsNIHNational Cancer Institute2023 to 2025$946,644September 1, 2022August 31, 2028RANJAN, ASHISHreporter.nih.gov
Epigenetic Regulation of Cutaneous TumorigenesisNIHNational Cancer Institute2021 to 2024$943,052August 1, 2020July 31, 2025CHEN, DAVIDreporter.nih.gov
tRNA modification reprogramming and translational remodeling in cancerNIHNational Cancer Institute2025$922,755August 28, 2025July 31, 2030GREGORY, RICHARD I.reporter.nih.gov
Defining impact of in situ activation of CD40 and type 1 interferon signaling on theTME and systemic T cell immunity in murine models and cancer patientsNIHNational Cancer Institute2024 to 2025$920,408May 1, 2024April 30, 2029BEG, AMER AZIZreporter.nih.gov
Investigating Transcriptional Elongation and Nuclear RNA Surveillance in MelanomaNIHNational Cancer Institute2021 to 2025$919,990April 1, 2021March 31, 2027INSCO, MEGAN LEIGHreporter.nih.gov
Investigating the role of the microbiota in enhancing memory T cell function during caloric restriction to promote melanoma controlNIHNational Cancer Institute2022 to 2024$904,050July 6, 2020March 31, 2026COLLINS, NICHOLASreporter.nih.gov
Advanced machine learning to empower ultra-sensitive liquid biopsy in melanoma and non-small cell lung cancerNIHNational Cancer Institute2023 to 2025$877,791July 4, 2023June 30, 2028WIDMAN, ADAMreporter.nih.gov
Wounding Therapy and PhotocarcinogenesisNIHNational Institute on Aging2025$877,297September 1, 2014August 31, 2027TRAVERS, JEFFREY B.reporter.nih.gov
Investigating p16 Loss in Pro-tumorigenic MetabolismNIHNational Cancer Institute2025$874,892April 1, 2020August 31, 2027AIRD, KATHERINE MARIEreporter.nih.gov
A dyadic digital skin cancer prevention intervention for adolescents and their parentsNIHNational Cancer Institute2025$861,930August 7, 2025July 31, 2028HECKMAN, CAROLYNreporter.nih.gov
Genomic biomarkers for cutaneous T-cell LymphomaNIHNational Cancer Institute2022 to 2024$861,358October 1, 2022January 31, 2026LIM, MEGAN S.reporter.nih.gov
Effect of the plantar skin microenvironment on tumor metastasis and drug toleranceNIHNational Cancer Institute2024 to 2025$852,164September 11, 2024August 31, 2029REBECCA, VITO WILLIAMreporter.nih.gov
The mechanism of extra-visual circadian photoentrainment in mammalsNIHNational Institute of General Medical Sciences2024 to 2025$838,555January 1, 2024December 31, 2027BUHR, ETHAN Dreporter.nih.gov
Identification of cancer neoepitope-specific T cells using novel high-throughput hydrogel based platformsNIHNational Cancer Institute2024 to 2025$835,309February 8, 2024January 31, 2027SCHNECK, JONATHAN Preporter.nih.gov
High dimensional digital pathology to investigate the tumor micro environment and its impact on response to therapyNIHNational Cancer Institute2021 to 2024$833,168September 1, 2020August 31, 2025MALIGA, ZOLTANreporter.nih.gov
Harnessing the therapeutic potential of histotripsy focused ultrasound-induced immunogenic cancer cell deathNIHNational Cancer Institute2024 to 2025$817,263August 3, 2024May 31, 2028CHO, CLIFFORDreporter.nih.gov
Preventing Melanoma Metastasis by Targeting Lipid Vulnerabilities in LymphNIHNational Cancer Institute2024 to 2025$814,991June 5, 2024May 31, 2029UBELLACKER, JESSALYNreporter.nih.gov
Harnessing the repetitive genome for cancer immunotherapyNIHNational Cancer Institute2023 to 2025$806,256August 1, 2023July 31, 2028GRIFFIN, GABRIEL K.reporter.nih.gov
PVSRIPO in melanomaNIHNational Cancer Institute2021 to 2024$794,128April 1, 2020March 31, 2025BEASLEY, GEORGIAreporter.nih.gov
Arsenic and other co-metals in the San Carlos Apache drinking waterNIHNational Cancer Institute2021 to 2025$785,110September 1, 2021August 31, 2026SAMUEL-NAKAMURA, CHRISTINEreporter.nih.gov
Investigating the role of GAPDHS in melanoma metabolism and metastasisNIHNational Cancer Institute2023 to 2025$779,256July 1, 2023June 30, 2028GILL, JENNIFER GIBSONreporter.nih.gov
Targeting Oncogenic NRAS, BRAF plus PI3'-Kinase Signaling for Melanoma TherapyNIHNational Cancer Institute2024 to 2025$770,000April 1, 2013March 31, 2029MCMAHON, MARTINreporter.nih.gov
Improving decision-making in patients with resectable melanoma and pre-existing autoimmune disease considering immune checkpoint inhibitionNIHNational Cancer Institute2021 to 2024$758,305April 16, 2020March 31, 2026LOPEZ-OLIVO, MARIA DE LOS ANGELESreporter.nih.gov
Engineered microtumor arrays for development of combination therapiesNIHNational Cancer Institute2021 to 2024$754,564September 9, 2020June 30, 2025KILIAN, KRISTOPHER ALANreporter.nih.gov
Integrative Approach to Comprehensive Analysis of High Throughput Data on a Cancer Center LevelNIHNational Cancer Institute2021 to 2025$751,310September 15, 2016August 31, 2026KOSSENKOV, ANDREW Vreporter.nih.gov
The role of MER/PROS1 in promoting stromal induced emergence from metastatic melanoma dormancyNIHNational Cancer Institute2023 to 2025$747,000September 1, 2022April 30, 2026FANE, MITCHELL EDWARDreporter.nih.gov
Discovery of PD-1/PDL-1 inhibitors from marine microbial natural productsNIHNational Cancer Institute2021 to 2024$741,335July 14, 2020June 30, 2025FENICAL, WILLIAMreporter.nih.gov
Measuring and manipulating metabolic fluxes in the tumor microenvironmentNIHNational Cancer Institute2023 to 2025$739,764September 1, 2022August 31, 2026BARTMAN, CAROLINEreporter.nih.gov
Investigating the PD-L1:NLRP3 signaling axis as a tumor intrinsic mechanism of adaptive resistance to anti-PD-1 antibody immunotherapyNIHNational Cancer Institute2024 to 2025$737,879August 1, 2020August 31, 2027HANKS, BRENT ALLENreporter.nih.gov
A novel pathway to overcome resistance to immunotherapy in melanomaNIHNational Cancer Institute2024 to 2025$732,000July 1, 2024June 30, 2029NORA VAZ SALEIRO, DIANAreporter.nih.gov
The role of stem-like CD8 T-cells in the abscopal responseNIHNational Cancer Institute2023 to 2025$727,395September 1, 2023August 31, 2028BUCHWALD, ZACHARY SCOTTreporter.nih.gov
Biomaterials-based metabolic rescue of dendritic cells for vaccine designNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$724,324January 1, 2021January 31, 2026ACHARYA, ABHINAVreporter.nih.gov
MAIT cell: microbiome crosstalk in antitumor immunityNIHNational Cancer Institute2024 to 2025$713,700December 15, 2023November 30, 2028TOBIN, RICHARDreporter.nih.gov
Neoadjuvant SEMA4D/ICB therapy for melanomaNIHNational Cancer Institute2025$709,554April 1, 2025March 31, 2030PAULOS, CHRYSTAL Mreporter.nih.gov
Determining the role of neutrophils in anti-tumor immunity and immune-related adverse events in the context of T cell-based therapiesNIHNational Cancer Institute2025$702,748March 17, 2025January 31, 2030MERGHOUB, TAHAreporter.nih.gov
A soft magnetoelastic microneedle patch for rapid skin cancer screeningNIHNational Cancer Institute2024 to 2025$701,812April 1, 2024March 31, 2029CHEN, JUNreporter.nih.gov
Practical Randomized Controlled Trial of Artificial Intelligence for Melanoma Diagnosis (PRACTA-MEL)NIHNational Cancer Institute2025$700,611March 11, 2025February 28, 2030ROTEMBERG, VERONICA MIRIAMreporter.nih.gov
Mechanism-informed identification of causal enhancer variantsNIHNational Human Genome Research Institute2025$694,900August 11, 2025June 30, 2029FARLEY, EMMA KIRSTENreporter.nih.gov
Improving prognosis prediction and therapy selection for cutaneous squamous cell carcinomas using artificial intelligenceNIHNational Institute of Biomedical Imaging and Bioengineering2024$693,156August 1, 2024July 31, 2027LOTTER, WILLIAM EDWARDreporter.nih.gov
Evaluating Pathways Involved in Melanoma InitiationNIHNational Cancer Institute2025$679,604August 1, 2025July 31, 2030ZON, LEONARD IRAreporter.nih.gov
Use of a non-human primate model to define the role of T cell immune responses in persistent Kaposi sarcoma-associated herpesvirus infection and Kaposi sarcoma pathogenesisNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$672,032February 1, 2023June 30, 2024MUTSVUNGUMA, LORRAINE ZVICHAPERAreporter.nih.gov
Elucidating the functional role and therapeutic potential of GPCR kinase 2 in primary and therapy-resistant basal cell carcinomaNIHNational Cancer Institute2025$669,949August 15, 2025July 31, 2030MYERS, BENJAMINreporter.nih.gov
Improving Mucosal Melanoma Therapy by Harnessing the Immunogenicity of r3LCMVNIHNational Cancer Institute2025$667,553January 1, 2025December 31, 2029POLLACK, SETH Mreporter.nih.gov
Microfluidic technology to isolate tumoricidal T-cells from peripheral bloodNIHNational Cancer Institute2023 to 2025$655,173August 1, 2023July 31, 2026SHIRURE, VENKTESHreporter.nih.gov
SESAME: Sun Exposure and Activities after Skin CAncer: Optimization of Mhealth IntErventionsNIHNational Cancer Institute2024 to 2025$651,635September 13, 2024August 31, 2027ALSHURAFA, NABILreporter.nih.gov
Modulating the localization and persistence of microbial neoantigen vaccine vectors to enhance therapeutic efficacyNIHNational Cancer Institute2025$638,120August 1, 2025May 31, 2030ARPAIA, NICHOLASreporter.nih.gov
Defining mechanisms of how immune checkpoint inhibitor-associated bacteria modulate tumor immunity in cancerNIHNational Cancer Institute2025$636,222April 1, 2025March 31, 2030MEISEL, MARLIESreporter.nih.gov
Role of Merkel cell polyomavirus small T antigen in persistent infectionNIHNational Institute of Allergy and Infectious Diseases2025$634,981June 17, 2025May 31, 2030SHUDA, MASAHIROreporter.nih.gov
Patient oriented research and mentoring program in dermatologic diseasesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$625,843May 2, 2023August 31, 2026ASGARI, MARYAM MANDANAreporter.nih.gov
High-throughput and multiplex single-molecule quantification and sorting of single EVNIHNational Cancer Institute2025$625,756August 12, 2025July 31, 2028ISSADORE, DAVID AARONreporter.nih.gov
Investigating CREB5-driven mechanisms of immune therapy resistanceNIHNational Cancer Institute2025$620,820December 11, 2024December 31, 2029MANGUSO, ROBERT THOMASreporter.nih.gov
Improving the platelet-mediated immune checkpoint inhibitor delivery for treating triple-negative breast cancerNIHNational Cancer Institute2025$619,764January 10, 2025December 31, 2029HU, QUANYINreporter.nih.gov
Synthetic Compartments to Rewire Inflammatory Signaling and Augment Immune Cell FunctionNIHNational Institute of Biomedical Imaging and Bioengineering2025$616,897August 8, 2025July 31, 2027GOOD, MATTHEW CHARLTONreporter.nih.gov
Development of small molecule selective inhibitors of neuronal nitric oxide synthase (nNOS) for melanoma treatmentNIHNational Cancer Institute2025$610,415June 23, 2025May 31, 2030YANG, SUNreporter.nih.gov
Optimization of Tannic Acid Lipid Nanoparticles for a Therapeutic mRNA Vaccine Against MelanomaNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$601,122August 1, 2023July 31, 2026FENTON, OWEN Sreporter.nih.gov
Characterization of relation between tissue viscoelasticity and tumor progression in aging tissuesNIHNational Institute on Aging2022 to 2025$583,226September 15, 2021August 31, 2027PARK, SEUNGMANreporter.nih.gov
Dissecting the tumor-intrinsic and -extrinsic roles of TBK1 in tumor immunityNIHNational Cancer Institute2025$569,782August 1, 2025July 31, 2028JENKINS, RUSSELL WILLIAMreporter.nih.gov
Elucidating the role of tumor cell-intrinsic hypoxia inducible factor (HIF)-1α and HIF-2α pathway activation in tumor immune evasionNIHNational Cancer Institute2023 to 2025$566,208June 12, 2023May 31, 2027TRUJILLO, JONATHAN Areporter.nih.gov
Mechanisms of non-genetic variation in melanomaNIHNational Cancer Institute2022 to 2024$550,940September 1, 2020August 31, 2025GARG, SALILreporter.nih.gov
Structure-function studies of LAG3 interactions with antibodies and cellular ligandsNIHNational Cancer Institute2025$549,962April 1, 2025March 31, 2030LUCA, VINCENT CHRISTOPHERreporter.nih.gov
Utilization of a novel dissimilarity approach to identify a novel mechanism of Merkel cell polyomavirus small tumor antigen nuclear import responsible for the development of Merkel cell carcinomaNIHNational Cancer Institute2025$547,875September 22, 2025August 31, 2028DYE, KRISTINE NICOLEreporter.nih.gov
Enhancing Melanoma TIL Efficacy with Multifactor mRNA-Mediated T Cell ReprogrammingNIHNational Cancer Institute2023 to 2024$538,582July 1, 2023August 22, 2024KATZ, SAMUEL Greporter.nih.gov
Mentoring in mHealth and Social Networking Interventions for CVD Risk ReductionNIHNational Heart, Lung, and Blood Institute2021 to 2024$517,154April 7, 2015December 31, 2025PAGOTO, SHERRY L.reporter.nih.gov
Recurrence and Resistance in the Aging Melanoma MicroenvironmentNIHNational Cancer Institute2025$510,431July 1, 2025June 30, 2030WEERARATNA, ASHANI Treporter.nih.gov
Regulation and function of subcellular RNA localization in neural crest cells and their derivativesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$497,935August 1, 2024July 31, 2027NORRIS, MEGAN Lreporter.nih.gov
Manipulating Lipid Metabolism to Reverse Immune Dysfunction in Solid CancersNIHNational Cancer Institute2025$496,391December 3, 2024November 30, 2029THAXTON, JESSICA Ereporter.nih.gov
Developing and testing a mobile health intervention to promote sun protection behaviors and skin examination among HispanicsNIHNational Institute on Minority Health and Health Disparities2024 to 2025$494,389April 15, 2022January 31, 2027NIU, ZHAOMENGreporter.nih.gov
Exploring palmitoylation dynamics: impacts on Cadherin-Catenin adhesion and lipid metabolism in the progression of melanoma lung metastasisNIHNational Cancer Institute2025$487,468September 1, 2025August 31, 2030CHEN, SHUYANGreporter.nih.gov
Interrogating the role of GTP metabolism in Rac1-driven phenotypes in melanomaNIHNational Cancer Institute2024 to 2025$484,281September 20, 2022July 31, 2027WOLFF, DAVID Wreporter.nih.gov
Kinase Signaling in Epidermal Homeostasis and Early NeoplasiaNIHNational Cancer Institute2024$479,217August 1, 2024July 31, 2029LEE, CAROLYN S.reporter.nih.gov
Genome-wide chromatin structure and function in Kaposi Sarcoma tissueNIHNational Cancer Institute2025$476,754July 11, 2025June 30, 2028MIRANDA, JJreporter.nih.gov
Dissecting clonal diversity in melanoma to overcome therapy resistance andmetastasisNIHNational Cancer Institute2021 to 2024$476,124April 6, 2020March 31, 2025REBECCA, VITO WILLIAMreporter.nih.gov
A Phase I Proof-of-Concept Study of CBL0137 Combined with Ipilimumab and Nivolumab Therapy in Locally Advanced or Metastatic MelanomaNIHNational Cancer Institute2023 to 2024$472,408July 1, 2023June 30, 2025ASTSATUROV, IGORreporter.nih.gov
Is ERBB4 a Driver of BRAF WT Melanomas?NIHNational Cancer Institute2024$471,175January 1, 2024December 31, 2026RIESE, DAVID J.reporter.nih.gov
Investigating novel targets for topical immunoprevention of keratinocytic skin cancerNIHNational Cancer Institute2025$462,092August 1, 2025July 31, 2027DICKINSON, SALLY Ereporter.nih.gov
Light-directed therapy of squamous cell head and neck cancer with a novel dual-acting chemotherapeutic.NIHNational Cancer Institute2023 to 2025$461,186August 3, 2023July 31, 2025HARTMAN, MATTHEW Creporter.nih.gov
Kinase Signaling in Epidermal Homeostasis and Early NeoplasiaNIHNational Cancer Institute2025$457,633August 1, 2024July 31, 2029LEE, CAROLYN S.reporter.nih.gov
Stress-induced immunosuppression via downregulation of interferon in triple negative breast cancerNIHNational Cancer Institute2024 to 2025$456,919July 1, 2024June 30, 2029GANDHI, SHIPRAreporter.nih.gov
Immune-Related Adverse Events in Melanoma Patients Receiving Adjuvant Immune Checkpoint Inhibitor TherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$455,472August 18, 2021July 31, 2026HASSAN, NOHA ABDELWAHAB HASSAN ALIreporter.nih.gov
Tumor Intrinsic Regulation of Immune Evasion Pathways in Breast CancerNIHNational Cancer Institute2021 to 2024$452,687May 12, 2021April 30, 2026ROSENBAUM, SHEERAreporter.nih.gov
Directing Cytokine Specificity Through Co-translational Carrier CouplingNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$449,459November 8, 2022October 31, 2024HUANG, YINA HSINGreporter.nih.gov
Identifying recurrent driver mutations in skin cancers by targeted UV damage sequencingNIHNational Institute of Environmental Health Sciences2023 to 2024$448,500March 10, 2023February 28, 2026WYRICK, JOHN Jreporter.nih.gov
Targeting melanoma promoting RNA modification pathway for melanoma therapy.NIHNational Cancer Institute2025$442,236January 1, 2025December 31, 2029WAJAPEYEE, NARENDRAreporter.nih.gov
The role of immunosuppression and environmental exposures on incident and subsequent keratinocyte carcinoma risk after solid organ transplantNIHNational Cancer Institute2025$441,578May 1, 2025April 30, 2030KAPLAN, DAVID Ereporter.nih.gov
Skin Lesion Archive and Annotation for Fusion and Earlier Skin Cancer DetectionNIHNational Cancer Institute2024$440,011April 3, 2024March 31, 2027STANLEY, RONALD Jreporter.nih.gov
Metabolic adaptations in melanoma brain metastasisNIHNational Cancer Institute2024 to 2025$435,827January 1, 2024December 31, 2025HERNANDO, EVAreporter.nih.gov
Tetraacylated lipid A enhancement of checkpoint blocking cancer immunotherapyNIHNational Cancer Institute2024 to 2025$435,827December 4, 2023November 30, 2025KASPER, DENNIS L.reporter.nih.gov
Targeting a PHGDH metabolic vulnerability in melanomaNIHNational Cancer Institute2024$433,256May 16, 2024April 30, 2026KARRETH, FLORIANreporter.nih.gov
Exploring anti-sense RNAs in melanocyte transformation and melanoma formationNIHNational Cancer Institute2025$433,256September 1, 2025August 31, 2027KARRETH, FLORIANreporter.nih.gov
Mechanisms of augmented UVB immunosuppressive responses by polyaromatic hydrocarbonsNIHNational Institute of Environmental Health Sciences2022 to 2024$432,815September 1, 2022August 31, 2025SAHU, RAVI PRAKASHreporter.nih.gov
TERT epigenetic and genomic variants in stage II melanoma as biomarkers of outcomeNIHNational Cancer Institute2023 to 2024$425,922February 1, 2023January 31, 2026POLSKY, DAVIDreporter.nih.gov
Unraveling Vascular Mediated Immune Exclusion in MelanomaNIHNational Cancer Institute2024$422,971June 15, 2024May 31, 2026KIM, MINAHreporter.nih.gov
A Novel Vaccine Adjuvant KOR-selective Small Molecule AgonistNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$420,730July 1, 2024May 31, 2026YOU, ZHAOYANGreporter.nih.gov
Leveraging combination histotripsy tumor ablation and N-dihydrogalactochitosan immunostimulation to advance osteosarcoma therapyNIHNational Cancer Institute2025$419,080August 1, 2025July 31, 2027TUOHY, JOANNEreporter.nih.gov
Understanding how the interaction between Lag3 deficiency and hypercholesterolemia impact anti-tumor immunity and cardiovascular disease in a melanoma modelNIHNational Cancer Institute2023 to 2024$418,787April 1, 2023March 31, 2025RODRIGUEZ, ANNABELLEreporter.nih.gov
Boosting Oncolytic HSV Immunotherapy by Enabling NecroptosisNIHNational Cancer Institute2025$416,040July 7, 2025June 30, 2027GUO, HONGYANreporter.nih.gov
Precision Tumor Sampling of Melanoma Using Laser MicrobiopsyNIHNational Cancer Institute2024 to 2025$413,832August 8, 2024July 31, 2027PAREKH, SAPUN Hreporter.nih.gov
Harnessing the potential of pharmacological small molecules to amplify VSV-based oncolytic viral therapyNIHNational Cancer Institute2024$408,966July 5, 2024June 30, 2027CHAMCHEU, JEAN CHRISTOPHERreporter.nih.gov
Improving Accuracy of Next-Generation Microscopy for Early Stage Metastatic Melanoma DetectionNIHNational Cancer Institute2024 to 2025$406,044January 15, 2024June 30, 2026WARREN, WARREN Sreporter.nih.gov
Special Public T Cell Receptor Sequences that Predict Outcomes for Cancer PatientsNIHNational Cancer Institute2023 to 2024$402,050January 1, 2023December 31, 2025POLLACK, SETH Mreporter.nih.gov
Cell intrinsic and extrinsic effects of zinc metabolism in therapy resistant melanomaNIHNational Cancer Institute2025$400,461April 1, 2025September 1, 2025AIRD, KATHERINE MARIEreporter.nih.gov
Next Generation Gene-Gun Delivered DNA and RNA Immunotherapeutic Vaccines for Melanoma.NIHNational Cancer Institute2023 to 2024$400,000September 21, 2023August 31, 2025FRIZZELL, HANNAHreporter.nih.gov
Mini-reflectance confocal microscope (Mini-RCM) for aiding skin cancer diagnosis and treatmentNIHNational Cancer Institute2025$400,000February 1, 2025January 31, 2027KANG, DONGKYUNreporter.nih.gov
A Novel Lentivector for Enhanced In Vivo Delivery of T Cell Receptors for Cell Therapy for Stage IV MelanomaNIHNational Cancer Institute2025$400,000September 15, 2025August 31, 2026JOHNSON, DAVID SCOTTreporter.nih.gov
Targeting Endogenous Retrovirus Regulation for Augmenting Cancer ImmunotherapyNIHNational Cancer Institute2022 to 2025$399,974August 1, 2020June 30, 2026VAN DEN EYNDE, MEAGHAN K.reporter.nih.gov
Targeted Delivery of Tumor Antigen esaRNA to the Spleen for Cancer ImmunotherapyNIHNational Cancer Institute2025$399,300September 10, 2025August 31, 2026CHAHAL, JASDAVEreporter.nih.gov
Unraveling the Connection: How Metabolism Shapes Mammalian Persister SurvivalNIHNational Cancer Institute2025$398,282April 18, 2025March 31, 2030ORMAN, MEHMET A.reporter.nih.gov
Lectikines for Immunotherapy against Ovarian CancerNIHNational Cancer Institute2024 to 2025$397,465February 1, 2024January 31, 2027MATOBA, NOBUYUKIreporter.nih.gov
Targeting the SKP2 Axis for Anti-melanoma TherapyNIHNational Cancer Institute2025$395,509April 4, 2025March 31, 2030INUZUKA, HIROYUKIreporter.nih.gov
Differential role of different NAD+ kinase Isoforms in melanoma metastasis-RelinquishmentNIHNational Cancer Institute2025$395,509May 1, 2022April 30, 2027PISKOUNOVA, ELENAreporter.nih.gov
Leveraging cancer-evolved resistance mechanisms to enhance EZH2 activity in adoptive T cellsNIHNational Cancer Institute2024$393,401June 1, 2024May 31, 2026TACKETT, ALANreporter.nih.gov
Overcoming therapy resistance in melanomaNIHNational Cancer Institute2024 to 2025$391,314April 1, 2024March 31, 2027SHENG, ZHIreporter.nih.gov
Novel Strategy to Augmenting Immunotherapy against MelanomaNIHNational Cancer Institute2024 to 2025$390,252March 1, 2024February 28, 2027YANG, JIN-MINGreporter.nih.gov
Targeting Rheostatic Mechanisms in MelanomaNIHNational Cancer Institute2025$388,875July 1, 2020June 30, 2027GROSSMANN, ALLIE H.reporter.nih.gov
Deciphering the role of tumor-macrophage crosstalk during metastatic dissemination to the peritoneumNIHNational Cancer Institute2022 to 2025$388,120September 1, 2021May 31, 2026HAN, JICHANGreporter.nih.gov
Develop IL13Ra1 for diagnosis of early-stage mycosis fungoidesNIHNational Cancer Institute2024 to 2025$387,402January 8, 2024December 31, 2026FUSCHIOTTI, PATRIZIAreporter.nih.gov
Discovery of PPI inhibitors for the FAK FAT domainNIHNational Cancer Institute2023 to 2024$385,717December 9, 2022November 30, 2024MARLOWE, TIMOTHY Areporter.nih.gov
PD-1/PD-L1 signaling at the interface between immune and stem cell crosstalkNIHNational Institute of Allergy and Infectious Diseases2025$384,250May 1, 2025April 30, 2027HARRIS, MELISSA Lreporter.nih.gov
Leveraging gnotobiotic models to study the gut microbiota and anti-tumor immunityNIHNational Cancer Institute2021 to 2024$383,591September 12, 2018February 28, 2025FESSLER, JESSICA LYNNreporter.nih.gov
A novel gene-based immunotherapy inducing melanoma destructionNIHNational Cancer Institute2024 to 2025$382,432March 15, 2024February 28, 2027MICHAEL, KATJAreporter.nih.gov
In vivo label free optical imaging of immune cells in human skinNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$373,723March 1, 2023December 31, 2025BALU, MIHAELAreporter.nih.gov
Programmable 'all-in-one' RNA as a molecular scaffold for targeted combinatorial innate immune activationNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$373,402January 1, 2024December 31, 2026WU, CONNIEreporter.nih.gov
Functional Landscape of Glycosylation in Skin CancerNIHNational Cancer Institute2023 to 2024$361,055February 1, 2023January 31, 2026KUDELKA, MATTHEW ROBERTreporter.nih.gov
Targeting epigenetic abnormalities to inhibit cutaneous squamous cell carcinomaNIHNational Cancer Institute2025$360,281July 31, 2025August 31, 2028KAWASUMI, MASAOKIreporter.nih.gov
Phase I Therapeutic Award: A Novel Engineered Bacterial Anticancer Immunotherapy for Merkel Cell CarcinomaNIHNational Cancer Institute2024$354,966February 21, 2024February 20, 2025HAN, SONGLEEreporter.nih.gov
Explainable Artificial Intelligence for Melanoma Recurrence Prediction via Integrative Modeling of Multiplexed Imaging with Transcriptomics and HistopathologyNIHNational Cancer Institute2024 to 2025$352,080February 9, 2024January 31, 2026WAN, GUIHONGreporter.nih.gov
Understanding mitochondrial mutations that drive human tissue agingNIHNational Institute on Aging2024 to 2025$347,576September 12, 2024June 30, 2029VANDIVER, AMY R.reporter.nih.gov
Discovery of fused heterocyclic pyrazine based novel anti-mitotic agents for metastatic melanomaNIHNational Institute of General Medical Sciences2024 to 2025$346,291July 22, 2024June 30, 2028BANERJEE, SOUVIKreporter.nih.gov
The role of the novel interface cell state in melanoma invasionNIHNational Cancer Institute2023 to 2024$346,032April 1, 2023March 31, 2026HUNTER, MIRANDA VICTORIAreporter.nih.gov
Rewired Signaling at the Nexus of Melanoma Metastasis and ResistanceNIHNational Cancer Institute2024$343,564August 1, 2024September 30, 2024RONAI, ZEEV A.reporter.nih.gov
PTP1b Inhibition Restores the Innate Anti-tumor Response During ChemotherapyNIHNational Cancer Institute2025$333,073July 1, 2025June 30, 2027UBIL, ERIC Sreporter.nih.gov
Dissecting the Role of Germline Genetics in RAS-Driven CancersNIHNational Cancer Institute2024 to 2025$327,456February 1, 2024August 31, 2025COLLINS, RYAN LEWISreporter.nih.gov
Improving decision-making for older adults with melanomaNIHNational Institute on Aging2024$322,000September 15, 2024August 31, 2026LEE, JAY SOONG-JINreporter.nih.gov
Analytical and Clinical Validation of an EPIC 900K v2 array-based methylation assay to predict recurrence in stage II melanomaNIHNational Cancer Institute2025$310,185April 3, 2025September 30, 2026POLSKY, DAVIDreporter.nih.gov
Toward safe, systemic immunotherapies for treatment of metastatic disease: Developing dendritic cell-biased immunomodulators with precise control over magnitude and timing of immune stimulationNIHNational Cancer Institute2023 to 2025$307,695August 11, 2021August 31, 2027BHAGCHANDANI, SACHINreporter.nih.gov
Using microsphere technology for the electrochemical measurement of genotoxicity.NIHNational Institute of Environmental Health Sciences2025$303,165August 19, 2025July 31, 2026SYKORA, PETERreporter.nih.gov
A Biobased Biodegradable Sunscreen that is Safe, Removes Environmental Impact, is Inclusive of all Skin Tones, and is for the Purpose of Eliminating Disparities in Melanoma Mortality RatesNIHNational Institute on Minority Health and Health Disparities2024$293,629August 18, 2024July 31, 2025CAL, ANDREWreporter.nih.gov
Tissue Damage-Driven Squamous Cell CarcinomaNIHNational Cancer Institute2025$278,822March 1, 2025August 31, 2026SOUTH, ANDREWreporter.nih.gov
Circulating cell free tumor DNA (ctDNA) in patients with immune checkpoint inhibitor associated inflammatory arthritis (ICI-IA): developing a biomarker to assess immunosuppressive drug safetyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$267,423September 16, 2025August 31, 2028BASS, ANNE Rreporter.nih.gov
Regulation and function of subcellular RNA localization in neural crest cells and their derivativesNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2024$264,780July 20, 2023July 31, 2024NORRIS, MEGAN Lreporter.nih.gov
Investigating the Role of Cancer-Associated Fibroblasts in Immunodetection of Mycosis FungoidesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$260,280June 13, 2024June 30, 2026JOHNSON, COURTNEY MICHELEreporter.nih.gov
Targeting mitochondrial vulnerabilities to drive intrinsic melanoma immunogenicityNIHNational Cancer Institute2024 to 2025$257,596April 4, 2024July 1, 2025LIANG, JIAXINreporter.nih.gov
Characterization of the Symptom Experience of Patients with Cutaneous Melanoma Receiving Immune Checkpoint Inhibitor TherapyNIHNational Cancer Institute2025$249,000February 1, 2024August 31, 2028HARRIS, CAROLYN STIGGEreporter.nih.gov
Targeting mitochondrial vulnerabilities to drive intrinsic melanoma immunogenicityNIHNational Cancer Institute2025$249,000April 4, 2024July 31, 2028LIANG, JIAXINreporter.nih.gov
Dissecting the Role of Germline Genetics in RAS-Driven CancersNIHNational Cancer Institute2025$248,999February 1, 2024August 31, 2028COLLINS, RYAN LEWISreporter.nih.gov
L-fucose-mediated enrichment of memory CD4+T cells and enhanced anti-melanoma immunityNIHNational Cancer Institute2024$236,321February 1, 2024January 31, 2026LAU, ERIC KIRKreporter.nih.gov
Targeting Tumor-Driven Immune Tolerance to Overcome Resistance to Hedgehog InhibitionNIHNational Cancer Institute2025$230,711April 1, 2025March 31, 2027KIM, ARIANNA Lreporter.nih.gov
Intestinal NOD2 and the microbiota enhance Coxsackievirus B3 pathogenesisNIHNational Institute of Allergy and Infectious Diseases2025$226,641December 5, 2024November 30, 2026KEESTRA-GOUNDER, ARINA MARIJKEreporter.nih.gov
Comparing NK cell profiles within melanoma tumors and pregnancy: Implications for novel immunotherapiesNIHNational Cancer Institute2025$217,863December 1, 2024November 30, 2026NORMAN, PAUL JOHNreporter.nih.gov
In vivo characterization of keratinocytes in the melanoma microenvironmentNIHNational Cancer Institute2021 to 2024$206,302July 1, 2021June 30, 2025MA, YILUNreporter.nih.gov
DISSECTING THE ROLE OF THE IMMUNE MICROENVIRONMENT IN MELANOMA BONE METASTASISNIHNational Cancer Institute2025$198,103February 1, 2025January 31, 2027HERNANDO, EVAreporter.nih.gov
Controlled Antigen Delivery for Prophylactic Cancer VaccinationNIHNational Cancer Institute2024 to 2025$194,213September 1, 2023April 30, 2028POGOSTIN, BRETTreporter.nih.gov
Elucidating the Function of LRP1 in APOE-mediated Suppression of Melanoma MetastasisNIHNational Cancer Institute2021 to 2024$187,905January 11, 2021May 16, 2024ADAKU, NNEOMAreporter.nih.gov
Title of Project * L-fucose-mediated enrichment of memory CD4+T cells and enhanced anti-melanoma immunityNIHNational Cancer Institute2025$182,325February 1, 2024August 31, 2026LAU, ERIC KIRKreporter.nih.gov
Fibrotic remodeling of lymph nodes disrupts T cell function in fibrosis and cancerNIHNational Cancer Institute2024 to 2025$182,098January 1, 2024May 18, 2025BINGHAM, GRACE Creporter.nih.gov
Mechanisms of perivascular melanoma dispersal and survival in the brainNIHNational Cancer Institute2022 to 2025$180,232January 1, 2022December 31, 2025WANG, SARAH Creporter.nih.gov
Modulating Human Microbiome Function to Enhance Immune Responses Against CancerNIHNational Cancer Institute2025$179,988January 1, 2025December 31, 2026SONNENBURG, JUSTIN Lreporter.nih.gov
The effect of aging on cDC1 function and CD8 T cell immunity in tumorsNIHNational Cancer Institute2025$176,040April 1, 2025March 31, 2027CHEN, CHANG-YU ALEXreporter.nih.gov
Building Reliable Vision-Language Assistant for Dermatology AI through Modeling Uncertainties in Multimodal LLMsNIHNational Institute of General Medical Sciences2025$175,470August 12, 2025June 30, 2029TAO, ZHIQIANGreporter.nih.gov
Electrical impedance dermography as a biomarker for basal and squamous cell carcinomaNIHNational Cancer Institute2025$174,939January 1, 2025December 31, 2026GROSSMAN, DOUGLASreporter.nih.gov
Characterizing the role of SRCAP in Epidermal Homeostasis and Squamous Cell CarcinomaNIHNational Cancer Institute2021 to 2024$170,308March 1, 2021February 28, 2025DROLL, STEPHENIEreporter.nih.gov
Epigenetic Regulation of Melanoma-Associated Fibroblast PlasticityNIHNational Cancer Institute2025$169,000August 1, 2025July 31, 2027FILIPESCU, DANreporter.nih.gov
Award of Task Order 3 entitled "A Dual AKT/PDPK1 Inhibitor for Actinic Keratosis and Skin Cancer Prevention in Immunocompromised Individuals"NIHNational Cancer Institute2024$166,186September 17, 2018June 16, 2024LYUBIMOV, ALEXANDERreporter.nih.gov
Evaluating a multimodality platform of tissue, blood and advanced imaging-based biomarkers to predict response to neoadjuvant immunotherapy and radiotherapy in melanomaNIHNational Center for Advancing Translational Sciences2025$163,310September 12, 2025September 11, 2027MITRA, DEVARATIreporter.nih.gov
Neoantigen-specific T cells in a novel cutaneous squamous cell carcinoma modelNIHNational Cancer Institute2023 to 2025$161,206August 1, 2023July 31, 2026ADAMS, ANNGELA CHRISTINAreporter.nih.gov
The role of alpha-synuclein in nucleolar DNA double-strand break repair and cellular senescenceNIHNational Institute on Aging2023 to 2025$161,206July 1, 2023June 30, 2027ARNOLD, MORIAH REBECCAreporter.nih.gov
Spatial Profiling of Melanocytic Tumors and Their MicroenvironmentNIHNational Cancer Institute2023 to 2024$160,500July 1, 2023June 30, 2025KIURU, MAIJA HELENA TUULIAreporter.nih.gov
The frequency and function of Type 3 Innate Lymphoid Cells regulates the melanoma tumor microenvironmentNIHNational Cancer Institute2024 to 2025$158,324July 1, 2024June 30, 2026O'CONNOR, MARGARETreporter.nih.gov
Stress-induced immunosuppression via downregulation of interferon in triple negative breast cancerNIHNational Cancer Institute2024$157,771July 1, 2024February 28, 2025GANDHI, SHIPRAreporter.nih.gov
SWI/SNF in ultraviolet radiation-induced chromatin alterationsNIHNational Institute of Environmental Health Sciences2025$156,250December 20, 2024November 30, 2026DE LA SERNA, IVANA Lreporter.nih.gov
Establishing an in-vivo Sleeping-Beauty Screen to Identify and Characterize Novel Drivers of Melanomagenesis in a Nevi-Prone Zebrafish Model.NIHNational Cancer Institute2025$155,500July 18, 2025June 30, 2027KENNY, COLIN Preporter.nih.gov
Novel Immunomodulators for Melanoma TherapyNIHNational Institute of General Medical Sciences2025$154,000July 18, 2025June 30, 2029MINOND, DMITRIYreporter.nih.gov
Conditional Agonism: PD1-Dependent Activation of 4-1BB for Enhanced SafetyNIHNational Cancer Institute2025$153,959September 1, 2025August 31, 2027SANDEY, MANINDERreporter.nih.gov
Development of immunocompetent melanoma brain metastases organoidsNIHNational Cancer Institute2024 to 2025$153,000March 6, 2024February 28, 2026RODRIGUEZ, ANALIZreporter.nih.gov
Directed Clonal Evolution of Drug Resistant BRAF Mutant Melanoma for Cross-Sensitization to MAPK HyperactivationNIHNational Cancer Institute2024 to 2025$152,324March 1, 2024February 28, 2027CHO, EUNICEreporter.nih.gov
Gadusol: An ancient sunscreen that protects metazoan developmentNIHNational Institute of General Medical Sciences2024 to 2025$149,348September 16, 2024September 15, 2026JOHNSON, KRISTIN LORETTEreporter.nih.gov
Defining the role of stress granules in cancer initiationNIHNational Cancer Institute2024 to 2025$149,348August 1, 2024July 31, 2027DRAKE, KYLE DAVIDreporter.nih.gov
Investigating the role of fatty acid metabolism in melanocyte differentiation: Insights into the metabolic requirements of developmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$145,978July 1, 2021August 31, 2024JOHNS, ELEANOR MAYreporter.nih.gov
Immunoediting in Cutaneous Squamous Cell CarcinomaNIHNational Cancer Institute2023 to 2025$143,512July 1, 2023August 31, 2027BORDEN, ELIZABETHreporter.nih.gov
Neural Mechanisms Driving Comorbid Parkinson's and MelanomaNIHNational Cancer Institute2022 to 2024$143,420July 1, 2022June 30, 2025DEL VALLE, PAMELAreporter.nih.gov
Interrogating the Fgl2-FcgRIIB axis: A novel mechanism mediating apoptosis of tumor-specific memory CD8+ T cellsNIHNational Cancer Institute2024 to 2025$141,043September 1, 2023January 2, 2026BENNION, KELSEYreporter.nih.gov
Harnessing hotspot specific differences among SF3B1 mutations to define novel mechanisms of tumorigenicity and targetability in solid malignanciesNIHNational Cancer Institute2023 to 2025$140,795July 1, 2023June 30, 2026BERGMAN, RILEYreporter.nih.gov
Data-driven mechanistic models of morphology-controlled Ras oncogenic signalingNIHNational Cancer Institute2025$140,097April 1, 2025March 31, 2027MAZLOOM FARSIBAF, HANIEHreporter.nih.gov
Combining Radiation, Allogeneic Natural Killer Immunotherapy, and PD-L1 blockade in Dogs with Naturally-Occurring MelanomaNIHNational Cancer Institute2023 to 2025$136,394May 1, 2023April 30, 2027RAZMARA, ARYANAreporter.nih.gov
DNA repair pathway coordination during damage processingNIHNational Institute of Environmental Health Sciences2023 to 2025$131,231January 1, 2024September 10, 2025SCHAICH, MATTHEW ALLENreporter.nih.gov
Tri-Signal Artificial Antigen Presenting Cells for Cancer ImmunotherapyNIHNational Cancer Institute2023 to 2025$129,437September 1, 2023February 28, 2026SHANNON, SYDNEY ROSEreporter.nih.gov
HMGB1 in EB-Associated Squamous Cell CarcinomaNIHNational Cancer Institute2023 to 2025$128,503August 1, 2023July 31, 2027BUI, KACEY LINNEA GUENTHERreporter.nih.gov
The role of tumor cell-of-origin-specific PDL1 on tumorigenesis and tumor progressionNIHNational Cancer Institute2023 to 2025$125,143August 3, 2023August 2, 2027ONTIVEROS, CARLOS OSCARreporter.nih.gov
Influence of Caffeine on MelanomaNIHNational Cancer Institute2022 to 2025$114,642January 1, 2023June 14, 2025BRATHWAITE, RODERICK DIONreporter.nih.gov
Immune-Related Adverse Events in Melanoma Patients Receiving Adjuvant Immune Checkpoint Inhibitor TherapyNIHNational Institute of Allergy and Infectious Diseases2025$113,868August 18, 2021July 31, 2026HASSAN, NOHA ABDELWAHAB HASSAN ALIreporter.nih.gov
Mitochondrial Regulation of Interferon Response in MelanomaNIHNational Cancer Institute2023 to 2025$105,504August 1, 2023December 31, 2025JOHNSON, MELISSAreporter.nih.gov
Dissecting the genetic basis of cancer immune evasion in squamous cell carcinomaNIHNational Cancer Institute2024 to 2025$100,012September 1, 2024August 31, 2026NICHOLSON, BENJAMINreporter.nih.gov
Defining tumor and blood-based immunogenomic signatures predicting response to immunotherapy in ovarian cancerNIHNational Cancer Institute2025$99,171December 1, 2024November 30, 2028MONSON, KELSEY Rreporter.nih.gov
Targeting TEAD in melanoma drug-tolerant persister cellsNIHNational Cancer Institute2024 to 2025$98,512July 5, 2024July 4, 2026OTT, CONNORreporter.nih.gov
Elucidating the role of mRNA m6A methylation in tumorigenesisNIHNational Cancer Institute2023 to 2024$98,168September 1, 2023March 14, 2025WILKINSON, EMMA ANNEreporter.nih.gov
Mechanism underlying how host B cells empower adoptively transferred Th17 cells with durable tumor immunityNIHNational Cancer Institute2024 to 2025$94,266February 1, 2024December 7, 2025COLE, ANNA CAMILLE ELYSEreporter.nih.gov
Investigating the epidermal microenvironment in melanoblast migration and invasion: a novel approach to understanding invasive melanomaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2024 to 2025$92,452January 1, 2023December 31, 2027RICHARDS, DENAYreporter.nih.gov
Development of Lipid Nanoparticles for B-cell Mediated ImmunotherapiesNIHNational Cancer Institute2025$90,765December 1, 2024November 30, 2028SUSIN PIRES, IVANreporter.nih.gov
Keratin and filament cell-cell junction cooperation in developmental and tumorigenic fate decisionsNIHNational Cancer Institute2025$90,720December 9, 2024November 30, 2028REDMOND, CATHERINE JULIAreporter.nih.gov
Identifying the Mechanism of Resistance to Immunotherapy in Merkel Cell Carcinoma (for Zachary Reinstein)NIHNational Cancer Institute2024 to 2025$88,938February 1, 2024January 31, 2026REINSTEIN, ZACHARY ZALEreporter.nih.gov
Paracrine signaling from keratinocytes establishes a pro-melanoma environmentNIHNational Cancer Institute2024 to 2025$88,374March 1, 2024February 28, 2027POKORNY, JENNYreporter.nih.gov
The Molecular Mechanism of Genetic Disorders Due to XPD MutationsNIHNational Institute of General Medical Sciences2024 to 2025$85,712August 1, 2024July 31, 2026HOAG, ALLYSON LYNNEreporter.nih.gov
Mechanisms of Macrophage-Mediated Immune Evasion in Residual TumorsNIHNational Cancer Institute2024 to 2025$84,954April 1, 2024March 31, 2027RAJ, JUDEreporter.nih.gov
Expanding access to perioperative and repurposed drug trials in melanoma and other solid tumorsNIHNational Cancer Institute2025$83,925September 10, 2025August 31, 2030LOWE, MICHAELreporter.nih.gov
The influence of lymph node metastasis on local and systemic anti-tumor immunityNIHNational Cancer Institute2024 to 2025$83,792August 1, 2024July 31, 2027VENTRE, KATHERINEreporter.nih.gov
The shared and distinct cistromes of YAP and TAZ in melanomaNIHNational Cancer Institute2025$81,750December 1, 2024November 30, 2026LANG, DEBORAHreporter.nih.gov
The interface of neurons and cancerNIHNational Cancer Institute2024 to 2025$81,222December 1, 2024August 31, 2026LUKASIK, KIMBERLYreporter.nih.gov
Investigating microphthalmia-associated transcription factor (MITF) and growth factors as initiators of melanomaNIHNational Cancer Institute2024 to 2025$81,003September 1, 2024August 31, 2027HONGO, RACHELreporter.nih.gov
Understanding B cell immunity in Merkel cell carcinomaNIHNational Cancer Institute2024 to 2025$80,685July 1, 2024June 30, 2026SCHNABEL, JULIAreporter.nih.gov
Merkel cell polyomavirus T-Antigen mediated reprogramming in adult epidermisNIHNational Cancer Institute2024 to 2025$80,636February 5, 2024August 11, 2025WEBER, MADISONreporter.nih.gov
Selection of oncogenic Ras mutations through tumor promotion mechanismsNIHNational Cancer Institute2022 to 2024$77,326December 1, 2022October 31, 2024BOLLAM, SAUMYA REDDYreporter.nih.gov
Endothelial Cell Cycle Control to Normalize the Tumor VasculatureNIHNational Cancer Institute2024 to 2025$76,960July 1, 2024June 30, 2027CAIN, SHELBYreporter.nih.gov
Defining the biochemical properties and implications of NRAS mutant-specific BRAF interactions in melanomaNIHNational Cancer Institute2024 to 2025$75,752August 1, 2024July 31, 2027LEW, RACHEL E.reporter.nih.gov
Impact of LAG3 on CD8+ T cell motility and migration in the context of cancer immunotherapyNIHNational Cancer Institute2025$75,520March 1, 2025February 28, 2026BAESSLER, ANDREW STEPHENreporter.nih.gov
Relative and synergistic contributions of PD1 and LAG3 on CD4+ T conventional cells in cancerNIHNational Cancer Institute2025$75,520December 1, 2025November 30, 2027MIHALIK, NICOLEreporter.nih.gov
Investigating the role of melanoma-adipocyte cell junctions in heterotypic communication and tumor progressionNIHNational Cancer Institute2023 to 2024$72,889July 13, 2023October 9, 2024PERLEE, SARAHreporter.nih.gov
Deciphering the mechanisms of nucleolar stress response during MCPyV infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$72,320August 1, 2024July 31, 2026PHAM, ALEXANDER MICHAELreporter.nih.gov
Defining the functional and spatial properties of tumor-specific tumor-infiltrating CD8 T cellsNIHNational Cancer Institute2024 to 2025$68,980May 1, 2024February 28, 2026AFEYAN, ALEXANDER BADRIG KJELLreporter.nih.gov
Investigating the epidermal microenvironment in melanoblast migration and invasion: a novel approach to understanding invasive melanomaNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$67,612January 1, 2023May 28, 2024RICHARDS, DENAYreporter.nih.gov
ICOS is an important mediator of both resident memory cell formation, and improved durability and persistence of anti-tumor T cellsNIHNational Cancer Institute2025$54,538February 20, 2025February 19, 2029WITTLING, MEGEN CLAIREreporter.nih.gov
Studying the role of skin pathobionts in Cutaneous T cell LymphomaNIHNational Institute of Allergy and Infectious Diseases2025$54,538September 1, 2025August 31, 2028GUMINA, MEGANreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of Pittsburgh at PittsburghPittsburgh, PA21$26.5 million0$0
New York University School of MedicineNew York, NY17$25.6 million0$0
University of PennsylvaniaPhiladelphia, PA16$23.9 million0$0
Massachusetts General HospitalBoston, MA12$20.6 million0$0
Dana-Farber Cancer InstBoston, MA11$16.9 million0$0
University of Michigan at Ann ArborAnn Arbor, MI10$16.8 million0$0
University of TX MD Anderson Can CTRHouston, TX14$16.6 million0$0
Stanford UniversityStanford, CA8$15.2 million0$0
University of UtahSalt Lake City, UT12$15.1 million0$0
Yale UniversityNew Haven, CT10$14.4 million0$0
H. Lee Moffitt Cancer CTR & Res InstTampa, FL12$14.3 million0$0
University of California, San FranciscoSan Francisco, CA8$13.6 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY13$13.6 million0$0
Brigham and Women's HospitalBoston, MA7$13.3 million0$0
University of California Los AngelesLos Angeles, CA7$11.4 million0$0
Columbia University Health SciencesNew York, NY10$10.9 million0$0
Institute for Systems BiologySeattle, WA1$10.6 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY10$10.4 million0$0
University of Colorado DenverAurora, CO11$10.3 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC8$10.1 million0$0
Weill Medical Coll of Cornell UnivNew York, NY8$9.8 million0$0
Johns Hopkins UniversityBaltimore, MD10$9.3 million0$0
Dartmouth CollegeHanover, NH5$8.9 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA5$8.2 million0$0
Northwestern University at ChicagoChicago, IL9$8.1 million0$0
Washington UniversitySaint Louis, MO6$8.1 million0$0
Duke UniversityDurham, NC9$8 million0$0
University of California-IrvineIrvine, CA4$7.5 million0$0
University of Alabama at BirminghamBirmingham, AL5$7.4 million0$0
Fred Hutchinson Cancer CenterSeattle, WA3$7.2 million0$0
University of California, San DiegoLa Jolla, CA5$7.1 million0$0
Wistar InstitutePhiladelphia, PA5$6.9 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA2$6.9 million0$0
Ohio State UniversityColumbus, OH7$6.7 million0$0
University of Southern CaliforniaLos Angeles, CA2$6.4 million0$0
Thomas Jefferson UniversityPhiladelphia, PA5$6.4 million0$0
Boston Immune Technologies and Therapeutics, Inc.Winchester, MA1$6.4 million0$0
Ut Southwestern Medical CenterDallas, TX6$6.3 million0$0
University of WashingtonSeattle, WA4$6 million0$0
University of ArizonaTucson, AZ7$5.9 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA4$5.8 million0$0
University of Wisconsin-MadisonMadison, WI4$4.6 million0$0
Albert Einstein College of MedicineBronx, NY3$4.6 million0$0
Mayo Clinic RochesterRochester, MN2$4.4 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ5$4.4 million0$0
University of KentuckyLexington, KY4$4.3 million0$0
University of Texas at AustinAustin, TX3$4.3 million0$0
University of VirginiaCharlottesville, VA5$4.2 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA3$4 million0$0
Wright State UniversityDayton, OH4$3.9 million0$0
Washington State UniversityPullman, WA3$3.9 million0$0
Beckman Research Institute/city of HopeDuarte, CA2$3.9 million0$0
La Jolla Institute for ImmunologyLa Jolla, CA1$3.5 million0$0
Cornell UniversityIthaca, NY2$3.5 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA3$3.5 million0$0
Roswell Park Cancer Institute CorpBuffalo, NY2$3.4 million0$0
University of LouisvilleLouisville, KY3$3.3 million0$0
University of New Mexico Health Scis CTRAlbuquerque, NM3$3.2 million0$0
University of Tennessee Health Sci CTRMemphis, TN1$3.1 million0$0
Vanderbilt UniversityNashville, TN3$3.1 million0$0
Surgivance, Inc.New York, NY2$3 million0$0
Veriskin, Inc.San Diego, CA1$3 million0$0
Methodist Hospital Research InstituteHouston, TX2$3 million0$0
Providence Portland Medical CenterPortland, OR1$3 million0$0
Baylor College of MedicineHouston, TX1$2.9 million0$0
Boston Children's HospitalBoston, MA3$2.8 million0$0
Oregon Health & Science UniversityPortland, OR3$2.6 million0$0
University of California at DavisDavis, CA4$2.5 million0$0
Rockefeller UniversityNew York, NY2$2.5 million0$0
Univ of Arkansas for Med ScisLittle Rock, AR3$2.4 million0$0
University of ChicagoChicago, IL5$2.4 million0$0
Georgetown UniversityWashington, DC1$2.3 million0$0
Van Andel Research InstituteGrand Rapids, MI2$2.2 million0$0
Case Western Reserve UniversityCleveland, OH2$2.2 million0$0
Northwestern UniversityChicago, IL2$2.2 million0$0
Indiana UniversityBloomington, IN1$2.2 million0$0
Emory UniversityAtlanta, GA6$2.1 million0$0
Phusis Therapeutics, Inc.La Jolla, CA1$2.1 million0$0
Nanometics, LLCLa Jolla, CA1$2 million0$0
Lipo-Immuno Tech, LLCMount Pleasant, SC1$2 million0$0
Sonoval LLCGaithersburg, MD1$2 million0$0
Enspectra Health, Inc.Mountain View, CA1$2 million0$0
7 Hills Pharma, LLCHouston, TX1$2 million0$0
Scripps Research Institute, theLa Jolla, CA1$2 million0$0
Children's Hospital of Los AngelesLos Angeles, CA1$1.8 million0$0
University of CincinnatiCincinnati, OH1$1.8 million0$0
George Washington UniversityWashington, DC1$1.8 million0$0
Pyrojas INCLong Island City, NY1$1.7 million0$0
University of HawaiiHonolulu, HI1$1.7 million0$0
University of RochesterRochester, NY1$1.6 million0$0
North Carolina State UniversityRaleigh, NC1$1.6 million0$0
University of ConnecticutStorrs, CT2$1.6 million0$0
Southern California Inst for Res/educLong Beach, CA1$1.5 million0$0
Harvard Medical SchoolBoston, MA5$1.5 million0$0
Kaiser Foundation Research InstituteOakland, CA1$1.4 million0$0
University of FloridaGainesville, FL2$1.4 million0$0
Creighton UniversityOmaha, NE1$1.3 million0$0
Dartmouth-Hitchcock ClinicLebanon, NH1$1.3 million0$0
Western University of Health SciencesPomona, CA1$1.3 million0$0
Celdara Medical, LLCLebanon, NH1$1.2 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025397$183,801,9620$0
2024410$168,972,7350$0
2023297$133,877,0970$0
2022211$96,152,5620$0
2021137$60,093,6920$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 12 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIHSeptember 7, 2027Not listedNotice number printed on 1 award here
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)PAR-27-089NIH93.396November 2, 2026Not listedSame assistance listing 93.396 as 124 awards here
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)PAR-27-088NIH93.396November 20, 2026Not listedSame assistance listing 93.396 as 124 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.396December 4, 2026Not listedSame assistance listing 93.396 as 124 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.396January 7, 2027$375,000Same assistance listing 93.396 as 124 awards here
Population Approaches to Reducing Alcohol-related Cancer Risk (R01 Clinical Trial Optional)PAR-25-221NIH93.396January 7, 2027Not listedSame assistance listing 93.396 as 124 awards here
Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)PAR-27-009NIH93.396January 25, 2027Not listedSame assistance listing 93.396 as 124 awards here
Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)RFA-CA-28-013NIH93.396February 9, 2027$700,000Same assistance listing 93.396 as 124 awards here
New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)PAR-25-272NIH93.396May 7, 2027Not listedSame assistance listing 93.396 as 124 awards here
New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)PAR-25-279NIH93.396May 7, 2027Not listedSame assistance listing 93.396 as 124 awards here
Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)RFA-CA-28-003NIH93.396June 11, 2027$600,000Same assistance listing 93.396 as 124 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIH93.396July 17, 2027Not listedSame assistance listing 93.396 as 124 awards here
Investigator-Focused Award (Parent R35)PAR-28-037NIH93.396October 4, 2027Not listedSame assistance listing 93.396 as 124 awards here
Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)RFA-CA-27-019NIH93.396October 19, 2027$300,000Same assistance listing 93.396 as 124 awards here
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)PA-25-301NIH93.396January 7, 2028Not listedSame assistance listing 93.396 as 124 awards here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)PA-25-304NIH93.396January 7, 2028Not listedSame assistance listing 93.396 as 124 awards here
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)PA-25-306NIH93.396January 7, 2028Not listedSame assistance listing 93.396 as 124 awards here
Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)PAR-24-311NIH93.396January 7, 2028$500,000Same assistance listing 93.396 as 124 awards here
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)PAR-25-043NIH93.396January 7, 2028$500,000Same assistance listing 93.396 as 124 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.