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Data / Research funding / Radiation Oncology

Radiation Oncology: 1,390 NIH awards ($1.7B) to 304 organizations

1,390 NIH awards ($1.7B) in the NIH spending category Radiation Oncology, to 304 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 1,390 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
NRG Oncology NCORP Research Base-BIQSFPNIHNational Cancer Institute2021 to 2025$54,340,726July 11, 2025July 31, 2026BRUNER, DEBORAH WATKINSreporter.nih.gov
Imaging and Radiation Oncology Core (IROC) GroupNIHNational Cancer Institute2021 to 2025$48,919,038May 26, 2014February 28, 2026KRY, STEPHEN Freporter.nih.gov
The Robert H. Lurie Comprehensive Cancer CenterNIHNational Cancer Institute2021 to 2025$32,389,955August 1, 1997July 31, 2030PLATANIAS, LEONIDAS C.reporter.nih.gov
Childhood Cancer Survivorship StudyNIHNational Cancer Institute2021 to 2025$27,522,831July 20, 1993November 30, 2026ARMSTRONG, GREGORYreporter.nih.gov
Pediatric Brain Tumor Consortium A multi-institutional consortium devoted to novel phase I and II clinical evaluations of experimental treatment approaches for pediatric CNS tumorsNIHNational Cancer Institute2021 to 2025$18,653,803April 1, 1999March 31, 2026ONAR-THOMAS, ARZUreporter.nih.gov
The Wake Forest Nonhuman Primate Radiation Survivor CohortNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$17,517,826August 1, 2020July 31, 2027CLINE, J. MARKreporter.nih.gov
SPORE in Brain CancerNIHNational Cancer Institute2021 to 2025$10,413,880September 1, 2008August 31, 2029LANG, FREDERICK Freporter.nih.gov
Colorado Head and Neck Cancer SPORENIHNational Cancer Institute2021 to 2025$10,073,085September 1, 2021August 31, 2026JIMENO, ANTONIOreporter.nih.gov
Clinical Trial Advancement and Development for SarcomasNIHNational Cancer Institute2022 to 2025$9,446,195September 11, 1997January 31, 2027VAN ETTEN, RICHARD A.reporter.nih.gov
Comparison of Symptom Burden/Toxicity, Neurocognitive Change, and Functional Outcomes in Pediatric Brain Tumor Patients Treated with Proton vs. Photon Radiotherapy.NIHNational Cancer Institute2021 to 2025$6,769,276March 1, 2021August 31, 2027KAHALLEY, LISA SCHUMreporter.nih.gov
Washington University/Siteman Cancer Center Lead Academic SiteNIHNational Cancer Institute2021 to 2025$6,572,668March 5, 2019February 28, 2026BARTLETT, NANCY Lreporter.nih.gov
CAUSAL: Cohort to Augment the Understanding of Sarcoma Survivorship Across the LifespanNIHNational Cancer Institute2023 to 2025$6,381,605September 22, 2021August 31, 2027FRIEDMAN, DEBRA L.reporter.nih.gov
Genomic and Microenvironmental Determinants, Temporal Dynamics, and Treatment Efficacy of Radiation-Based Combination TherapiesNIHNational Cancer Institute2022 to 2025$6,280,793September 14, 2022July 31, 2027CHAN, TIMOTHY AN-THYreporter.nih.gov
OSU as a Network Lead Academic Participating Site for the NCI NCTNNIHNational Cancer Institute2021 to 2025$5,610,699March 28, 2019February 28, 2026VERSCHRAEGEN, CLAIRE F.reporter.nih.gov
Understanding and Mimicking TCR Recognition with Therapeutic Monoclonal Antibodies.NIHNational Cancer Institute2021 to 2025$5,214,422August 14, 2020July 31, 2027SCHEINBERG, DAVID Areporter.nih.gov
One-click Automated 3D Treatment Planning for Radiopharmaceutical TherapyNIHNational Cancer Institute2021 to 2024$5,076,565April 1, 2018June 30, 2025WICKRE, PAULreporter.nih.gov
Development of Radiation/Nuclear Medical Countermeasures (MCMs) and Biodosimetry DevicesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,879,349July 1, 2023June 30, 2026NGUYEN, THERESAreporter.nih.gov
Medical University of South Carolina NCORP Community SiteNIHNational Cancer Institute2021 to 2025$4,774,115August 1, 2014July 31, 2026MARSHALL, DAVID T.reporter.nih.gov
Rochester Network Lead Academic Participating SiteNIHNational Cancer Institute2021 to 2025$4,321,570March 7, 2019February 28, 2026BARR, PAUL Mreporter.nih.gov
Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and ModeratorsNIHNational Cancer Institute2021 to 2025$4,123,295June 15, 2021August 31, 2026FIGUEIREDO, JANE C.reporter.nih.gov
Washington University Paul Calabresi K12 Career Development Award for Clinical OncologyNIHNational Cancer Institute2021 to 2025$4,041,207April 16, 2012April 30, 2027GOVINDAN, RAMASWAMYreporter.nih.gov
(PQ3) Addressing Cancer Treatment Disparities for Persons with HIVNIHNational Cancer Institute2021 to 2025$4,038,411June 15, 2021May 31, 2027SILVERBERG, MICHAEL Jreporter.nih.gov
A personalized approach using hypoxia resolution to guide curative-intent radiation dose reduction to 30 Gy: A novel de-escalation paradigm for HPV-associated oropharynx cancersNIHNational Cancer Institute2021 to 2025$4,028,888March 3, 2020March 31, 2030LEE, NANCY Yreporter.nih.gov
Commercializing CivaSheet for Pancreatic Cancer PatientsNIHNational Cancer Institute2023 to 2025$3,999,206September 13, 2016June 30, 2026PEREZ, KRISTYreporter.nih.gov
Combining Targeted RIT and Synergistic Novel Agent-RenewalNIHNational Cancer Institute2021 to 2025$3,984,924June 1, 2020May 31, 2027OROZCO, JOHNNIE JOSEreporter.nih.gov
Targeting DNA Repair for Cancer Therapy.NIHNational Cancer Institute2021 to 2025$3,977,199August 1, 2017January 31, 2032GLAZER, PETER Mreporter.nih.gov
Training Program in Nervous System TumorsNIHNational Cancer Institute2021 to 2025$3,975,290September 26, 2001August 31, 2027PLOTKIN, SCOTT Rreporter.nih.gov
Bringing 4π radiation therapy to the clinicNIHNational Cancer Institute2022 to 2024$3,911,244May 6, 2022April 30, 2025YONEMOTO, JAYreporter.nih.gov
Physician Scientist Training in Clinical OncologyNIHNational Cancer Institute2021 to 2025$3,870,097September 30, 1997June 30, 2030SCHUCHTER, LYNN M.reporter.nih.gov
High Energy and Spatial Resolution Multi-Isotope SPECT Imaging of Targeted Alpha-Emitters and their DaughtersNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2025$3,827,636September 1, 2021May 31, 2027DU, YONGreporter.nih.gov
Risk prediction and longitudinal assessment of cardiotoxicity and functional capacity trajectory in NSCLC patientsNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,805,993June 1, 2021May 31, 2027LIAO, ZHONGXINGreporter.nih.gov
OSU K12 Training Grant in OncologyNIHNational Cancer Institute2021 to 2025$3,775,515September 9, 2008June 30, 2029CARSON, WILLIAM E.reporter.nih.gov
Overcoming Hypoxic Resistance in Non-Small Cell Lung Cancer By Targeting Mitochondrial MetabolismNIHNational Cancer Institute2021 to 2025$3,588,137September 22, 2021August 31, 2027DENKO, NICHOLAS C.reporter.nih.gov
An Investigation of the Molecular Mechanisms for and Prediction of the Severity of Cancer Chemotherapy-Related Fatigue Using a Multi-staged Integrated Omics ApproachNIHNational Cancer Institute2021 to 2025$3,538,642July 3, 2019June 30, 2026KOBER, KORD MICHAELreporter.nih.gov
Evolution of gliomas during treatment and resistanceNIHNational Cancer Institute2021 to 2025$3,464,231April 1, 2015June 30, 2026BEROUKHIM, RAMEENreporter.nih.gov
Preclinical optimization of ultra-high dose rate (FLASH) radiotherapy parameters for translational relevanceNIHNational Cancer Institute2022 to 2025$3,463,660September 1, 2022August 31, 2027SCHUELER, EMILreporter.nih.gov
Improving radiolabeled imaging and targeting of HER2 positive EG cancers using lovastatinNIHNational Cancer Institute2021 to 2025$3,432,890December 1, 2020November 30, 2026LEWIS, JASON S.reporter.nih.gov
Real-time MRI-guided adaptive radiotherapy of unresectable pancreatic cancerNIHNational Cancer Institute2021 to 2025$3,323,920August 13, 2021July 31, 2026OTAZO, RICARDOreporter.nih.gov
Using experimentally-guided multi-scale modeling to determining the mechanism of FLASH tissue sparingNIHNational Cancer Institute2022 to 2025$3,306,088September 5, 2022July 31, 2027SCHUEMANN, JAN PATRICK OSCARreporter.nih.gov
Multimodality Neuroimaging Evaluation of Cognitive Functioning in Lower Grade AstrocytomaNIHNational Cancer Institute2022 to 2025$3,280,932September 9, 2022August 31, 2027LI, YANreporter.nih.gov
Hyperpolarized C-13 MRI Techniques to Monitor Radiation Therapy Response in Prostate Cancer PatientsNIHNational Cancer Institute2021 to 2025$3,266,535July 1, 2021June 30, 2027VIGNERON, DANIEL Breporter.nih.gov
An Ionizing Radiation Acoustics Imaging (iRAI) Approach for guided Flash RadiotherapyNIHNational Cancer Institute2022 to 2025$3,262,628September 20, 2022August 31, 2027EL NAQA, ISSAM M.reporter.nih.gov
Addressing Chemoresistance in Pancreatic and Ovarian Cancers: Photodynamic Priming and Repurposing of Tetracyclines using Targeted Photo-Activable Multi-Inhibitor LiposomeNIHNational Cancer Institute2021 to 2025$3,218,280April 1, 2021March 31, 2027HUANG, HUANG CHIAOreporter.nih.gov
Developing preclinical xenograft models in zebrafish.NIHOffice of the Director, National Institutes of Health2022 to 2025$3,178,512March 1, 2022February 28, 2026LANGENAU, DAVID MICHAELreporter.nih.gov
Simultaneous MRI/US for real-time liver ablation guidance and confirmationNIHNational Cancer Institute2022 to 2025$3,174,892August 15, 2022July 31, 2027HOLMES, JAMES Hreporter.nih.gov
Next Generation Therapies for Fertility Preservation in Male Cancer PatientsNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$3,165,939May 15, 2020April 30, 2025ORWIG, KYLE EDWINreporter.nih.gov
Precision magnetic hyperthermia by integrating magnetic particle imagingNIHNational Cancer Institute2021 to 2025$3,163,595July 1, 2021June 30, 2027BULTE, JEFF W.reporter.nih.gov
Advanced diffusion MRI for evaluating early response to radiation treatment in cervical cancerNIHNational Cancer Institute2021 to 2025$3,147,525April 1, 2021March 31, 2026RAKOW-PENNER, REBECCA ANNreporter.nih.gov
Transrectal Histotripsy for Focal Ablation of Prostate CancerNIHNational Cancer Institute2022 to 2025$3,132,373September 23, 2022August 31, 2027SCHADE, GEORGE Rreporter.nih.gov
UM Calabresi Clinical Oncology Research Career Development AwardNIHNational Cancer Institute2021 to 2025$3,093,598June 29, 2018August 31, 2028POLLACK, ALANreporter.nih.gov
Understanding and targeting MAPK pathway activation in NF1-deficient malignant peripheral nerve sheath tumor (MPNST)NIHNational Cancer Institute2021 to 2025$3,076,366April 1, 2021March 31, 2026CHI, PINGreporter.nih.gov
The Role of the Gut Microbiome and Short Chain Fatty Acids in the Regulation of Inflammation and Neuropsychological Symptoms in Patients with Head and Neck CancerNIHNational Institute of Nursing Research2022 to 2025$3,064,029May 9, 2022February 28, 2027XIAO, CANHUAreporter.nih.gov
Personalized Motion Management for Truly 4D Lung RadiotherapyNIHNational Cancer Institute2021 to 2025$3,062,893July 16, 2021June 30, 2027SAWANT, AMITreporter.nih.gov
CD28-KITv CAR T cells with PD-1 dominant negative receptorNIHNational Cancer Institute2024 to 2025$3,061,861March 1, 2024February 28, 2026ADUSUMILLI, PRASAD S.reporter.nih.gov
Mitigation of Radiation Induced Gastrointestinal Syndrome.NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,026,290August 1, 2023July 31, 2026NORRIS, ANDREW JOHNreporter.nih.gov
Prognostic and Predictive Digital Tissue Image Assay for Prostate CancerNIHNational Cancer Institute2022 to 2025$3,008,190September 5, 2022August 31, 2027MADABHUSHI, ANANTreporter.nih.gov
National Clinical Trials Network Research at the University of WisconsinNIHNational Cancer Institute2021 to 2025$3,007,329March 6, 2019February 28, 2026WISINSKI, KARI BRAUNreporter.nih.gov
The REASON Score: An Epigenetic And Clinicopathologic Score to Predict Risk of Poor Survival in Early Stage Oral Squamous Cell Carcinoma PatientsNIHNational Institute of Dental & Craniofacial Research2022 to 2025$3,001,101August 11, 2022May 31, 2027VIET, CHI T.reporter.nih.gov
Comprehensive Liquid Biomarkers to Personalize Therapy in Renal Cell CarcinomaNIHNational Cancer Institute2025$2,984,495September 23, 2025August 31, 2029MCKAY, RANA RAMZIreporter.nih.gov
Prostate Cancer Radio-Pathomics for Differentiating Clinically Significant DiseaseNIHNational Cancer Institute2021 to 2025$2,965,890March 1, 2021August 31, 2026LAVIOLETTE, PETER Sreporter.nih.gov
Blood-based monitoring of bladder-sparing trimodality therapy for muscle-invasive bladder cancerNIHNational Cancer Institute2022 to 2025$2,958,001September 1, 2022August 31, 2027MIYAMOTO, DAVID T.reporter.nih.gov
SynerGel: A Novel Tumor Microenvironment-Modulating Hydrogel for Local ImmunotherapyNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,957,648July 1, 2021April 30, 2027YOUNG, SIMONreporter.nih.gov
Mechanistic Risk Prediction of Radiation Therapy CardiotoxicityNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,943,376July 15, 2020June 30, 2026KY, BONNIEreporter.nih.gov
Human-like automated radiotherapy treatment planning via imitation learningNIHNational Cancer Institute2021 to 2025$2,937,704May 18, 2021April 30, 2027JIANG, STEVE BINreporter.nih.gov
Personalized Risk Prediction to Reduce Cardiovascular Disease in Childhood Cancer SurvivorsNIHNational Cancer Institute2022 to 2025$2,933,453July 15, 2022April 30, 2027HOWELL, REBECCA MAUREENreporter.nih.gov
Radiogenomic Credentialing of Head and Neck Cancer ModelsNIHNational Cancer Institute2021 to 2025$2,932,365December 1, 2020November 30, 2026SESHADRI, MUKUNDreporter.nih.gov
Molecular Mechanisms of Drug Resistance in Primary Brain TumorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,926,627January 1, 2018November 30, 2025MELLINGHOFF, INGO Kreporter.nih.gov
Quantitative Glioblastoma Margin and Infiltration Mapping with Advanced Diffusion-Relaxation MRINIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,908,680August 15, 2022May 31, 2027WESTIN, CARL-FREDRIKreporter.nih.gov
Development of functional magnetic resonance imaging-guided adaptive radiotherapy for head and neck cancer patients using novel MR-Linac deviceNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,900,314August 13, 2019May 31, 2025FULLER, CLIFTON DAVIDreporter.nih.gov
Development of a Virtual Preclinical CT Platform for Advanced Imaging and Theranostics in Head and Neck Cancer ResearchNIHNational Cancer Institute2025$2,896,024September 23, 2025August 31, 2029BADEA, CRISTIAN Treporter.nih.gov
UNC Oncology K12NIHNational Cancer Institute2021 to 2025$2,880,051September 17, 2007June 30, 2029KIM, WILLIAM Y.reporter.nih.gov
The role of Galectin-1 in shaping the immune suppressive landscape in head and neck cancerNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,863,227April 14, 2021February 28, 2026LE, QUYNH-THU XUANreporter.nih.gov
A Testing Program to Identify Novel Agents for Treatment of Pediatric and AYA High-Risk Sarcoma, Kidney and Liver CancerNIHNational Cancer Institute2021 to 2025$2,862,121September 1, 2021June 30, 2026KURMASHEVA, RAUSHANreporter.nih.gov
Overcoming hypoxic resistance to anti-cancer therapyNIHNational Cancer Institute2021 to 2025$2,861,132December 15, 2020May 31, 2026DENKO, NICHOLAS C.reporter.nih.gov
Longitudinal Spatial-Nonspatial Decision Support for Competing Outcomes in Head and Neck Cancer TherapyNIHNational Cancer Institute2021 to 2025$2,856,525March 1, 2021February 28, 2027MARAI, GEORGETA-ELISABETAreporter.nih.gov
Glycosaminoglycans to Treat and Prevent Radiation-Induced Oral MucositisNIHNational Institute of Dental & Craniofacial Research2021 to 2023$2,826,053September 20, 2021February 28, 2025SAVAGE, JUSTIN RODNEYreporter.nih.gov
NANOPHOTOSENSITIZERS FOR REGENERATIVE PHOTOTHERAPYNIHNational Cancer Institute2022 to 2025$2,822,017August 4, 2021July 31, 2027ACHILEFU, SAMUELreporter.nih.gov
Targeting apoptotic cells to enhance radiotherapyNIHNational Cancer Institute2022 to 2025$2,817,814September 22, 2022August 31, 2027RAO, JIANGHONGreporter.nih.gov
Advancing Cancer Therapy through Groundbreaking Research in Radiation BiologyNIHNational Cancer Institute2021 to 2022$2,817,393January 4, 2016April 30, 2023KIRSCH, DAVID GUYreporter.nih.gov
Re-wiring PDAC Tumor Immunity Through Dendritic CellsNIHNational Cancer Institute2021 to 2025$2,793,464September 22, 2021August 31, 2026DENARDO, DAVID Greporter.nih.gov
Biomarker Approaches to Individualizing Systemic Therapy for High Risk Prostate CancerNIHNational Cancer Institute2021 to 2024$2,771,966July 1, 2020June 30, 2025FENG, FELIX YI-CHUNGreporter.nih.gov
Targeting Nucleotide Metabolism to Overcome Therapy Resistance in GlioblastomaNIHNational Cancer Institute2021 to 2025$2,760,954March 1, 2021February 28, 2026WAHL, DANIEL Rreporter.nih.gov
Base-Edited Hematopoietic Stem and Progenitor Cells To Enable Safe Use Of Highly Potent CD33-Targeted RadioimmunotherapyNIHNational Cancer Institute2022 to 2025$2,758,516July 1, 2022June 30, 2027WALTER, ROLAND BRUNOreporter.nih.gov
Enhancing MAPK-targeted Therapy in PDX Models of BRAF-Mutant Pediatric Brain TumorsNIHNational Cancer Institute2021 to 2025$2,752,745March 8, 2021February 28, 2026BURMA, SANDEEPreporter.nih.gov
Image-guided combination therapies for radiotherapy-induced neurocognitive impairment in pediatric brain tumor survivorsNIHNational Cancer Institute2021 to 2025$2,750,972July 12, 2021June 30, 2027NGEN, ETHEL JOSOreporter.nih.gov
Minibeam Radiation Therapy Enhanced Delivery of Nanoparticle Anticancer Agents to Pancreatic Cancer TumorsNIHNational Cancer Institute2021 to 2025$2,742,888April 1, 2021March 31, 2027ZAMBONI, WILLIAM Creporter.nih.gov
Lung Functional Avoidance Radiotherapy Using Hyperpolarized Xenon MRINIHNational Cancer Institute2021 to 2025$2,741,941September 17, 2021August 31, 2027RUSET, IULIAN CONSTANTINreporter.nih.gov
Development of a Clinical CEST MR Fingerprinting Method for Treatment Response Assessment in Brain MetastasesNIHNational Cancer Institute2022 to 2025$2,738,894April 1, 2022July 31, 2027COHEN, OURIreporter.nih.gov
Minimizing salivary gland and renal toxicity arising from PSMA-targeted alpha therapyNIHNational Cancer Institute2022 to 2025$2,733,165May 1, 2022April 30, 2027PILLARSETTY, NAGAVARAKISHOREreporter.nih.gov
Engineered anti-PSCA antibodies for immunoPET and targeted therapy of pancreatic cancerNIHNational Cancer Institute2022 to 2025$2,731,178January 1, 2022December 31, 2026WU, ANNA Mreporter.nih.gov
Conformal Total Body and Marrow Irradiation for LeukemiaNIHNational Cancer Institute2021 to 2024$2,727,228September 13, 2011December 31, 2025HUI, SUSANTA Kreporter.nih.gov
The ASPIRES Study: Activating Cancer Survivors and their Primary Care Providers to Increase Colorectal Cancer ScreeningNIHNational Cancer Institute2021 to 2025$2,725,531March 1, 2021March 31, 2025HENDERSON, TARA OLIVEreporter.nih.gov
Improved Radiation Therapy of Hypoxic Tumor Regions by Integrated PET, EPR, and MR Imaging - Resubmission 01NIHNational Cancer Institute2021 to 2024$2,718,874January 1, 2020December 31, 2025CHEN, CHIN-TUreporter.nih.gov
Novel Approaches to CD33-Directed RadioimmunotherapyNIHNational Cancer Institute2022 to 2025$2,717,065December 1, 2024November 30, 2026WALTER, ROLAND BRUNOreporter.nih.gov
Hyperspectral Single Photon Imaging of Targeted Alpha-EmittersNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,707,977July 1, 2021March 31, 2026DU, YONGreporter.nih.gov
Utility of memantine in preventing cognitive dysfunction in children receiving cranial radiotherapyNIHNational Cancer Institute2022 to 2025$2,688,046September 18, 2019December 31, 2026LAACK, NADIA Nreporter.nih.gov
MT-125 for the Therapeutic Treatment of GlioblastomaNIHNational Cancer Institute2023 to 2025$2,666,500April 1, 2023December 31, 2025ROSENFELD, STEVEN Sreporter.nih.gov
Long-term Oral Complications of an Established Head and Neck Cancer Cohort- Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients: OraRadNIHNational Institute of Dental & Craniofacial Research2021 to 2022$2,651,122September 26, 2012June 30, 2024BRENNAN, MICHAEL Treporter.nih.gov
CardioWatch: An Omics-Based Prediction Assay for Cardiac Late Effects ofAcute RadiationNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,645,440July 1, 2020July 31, 2027KANHOLM, TOMASreporter.nih.gov
Disrupting the Prostate Tumor Microenvironment in African American Men to Promote Response to Immuno-Modulatory TherapyNIHNational Cancer Institute2022 to 2025$2,642,372September 1, 2022August 31, 2027YAMOAH, KOSJreporter.nih.gov
Development of CD46 theranostics for imaging and treatment of multiple myelomaNIHNational Cancer Institute2022 to 2025$2,633,937July 1, 2022June 30, 2027FLAVELL, ROBERT RICHARDreporter.nih.gov
Expansion of Tumoroid Models for Precise Treatment of the Rectal Cancer PatientNIHNational Cancer Institute2021 to 2025$2,633,017March 1, 2025June 30, 2025SMITH, JESSE JOSHUAreporter.nih.gov
PSMA-targeted AuNPs for MR guided radiotherapy and radiosensitizationNIHNational Cancer Institute2021 to 2024$2,622,473March 1, 2021February 28, 2026BASILION, JAMES PETERreporter.nih.gov
Development of 211Astatine-Conjugated Anti-CD45 Antibody-Based Conditioning for Hematopoietic Stem Cell Gene Therapy and EditingNIHNational Heart, Lung, and Blood Institute2021 to 2023$2,608,434May 15, 2020April 30, 2026WALTER, ROLAND BRUNOreporter.nih.gov
PLK1 and EGFR targeted nanoconstruct as a monotherapy and a radiation sensitizer for lung cancerNIHNational Cancer Institute2023 to 2025$2,602,500July 6, 2023August 31, 2027NGAMCHERDTRAKUL, WORAPOLreporter.nih.gov
Constrained Disentanglement (CODE) Network for CT Metal Artifact Reduction in Radiation TherapyNIHNational Institute of Biomedical Imaging and Bioengineering2021$2,593,824September 15, 2021September 14, 2025WANG, GEreporter.nih.gov
Targeting ATM to boost systemic effects of radiotherapy and immunotherapyNIHNational Cancer Institute2021 to 2025$2,585,426March 9, 2021February 28, 2026ZHANG, JENNIFER YUNYANreporter.nih.gov
UCSF Paul Calabresi K12 Career Development Program in Clinical OncologyNIHNational Cancer Institute2021 to 2025$2,581,772July 1, 2021June 30, 2027BERGSLAND, EMILY Kreporter.nih.gov
Mechanisms of Human DNA Double-Strand Break Repair via Quantitative Single-Molecule ImagingNIHNational Institute of General Medical Sciences2021 to 2025$2,576,334February 1, 2020December 31, 2029ROTHENBERG, ELIreporter.nih.gov
Linear energy transfer (LET) dependencies for understanding pancreatic tumor control and relevant molecular endpoints in support of RBE-based heavy-ion radiotherapyNIHNational Cancer Institute2021 to 2025$2,554,187January 1, 2021December 31, 2026AMUNDSON, SALLY A.reporter.nih.gov
Molecular Biomarkers of Long-Term Response to Androgen Deprivation Therapy and Radiation in Prostate CancerNIHNational Cancer Institute2022 to 2025$2,551,647January 1, 2022December 31, 2026MAHER, CHRISTOPHER Areporter.nih.gov
Highly selective targeted theranostics for prostate cancersNIHNational Cancer Institute2021 to 2024$2,486,011August 11, 2021July 31, 2026BASILION, JAMES PETERreporter.nih.gov
Radiation and dendritic cells to hepatomas to improve immunotherapy responseNIHNational Cancer Institute2022 to 2025$2,485,861September 1, 2022August 31, 2027PARK, SEAN Sreporter.nih.gov
High Resolution Ultrasound in Interventional RadiologyNIHNational Cancer Institute2022 to 2025$2,483,017March 4, 2022February 28, 2027FERRARA, KATHERINE Wreporter.nih.gov
Relative Immunological Effectiveness (RIE) of Carbon Ion Radiation Therapy for Pancreatic CancerNIHNational Cancer Institute2021 to 2025$2,481,775January 14, 2021December 31, 2026GUHA, CHANDANreporter.nih.gov
Predicting Fracture Risk in Patients Treated with Radiotherapy for Spinal Metastatic DiseaseNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,481,164April 1, 2020March 31, 2026ALKALAY, RON Nreporter.nih.gov
IND-enabling toxicology studies to reach IND approval for a proprietary biologic to treat oral mucositis in cancer patientsNIHNational Institute of Dental & Craniofacial Research2023 to 2024$2,470,033September 21, 2023August 31, 2025YOUNG, CHRISTIANreporter.nih.gov
Imaging signatures of genetic mutations in glioblastoma using machine learningNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,467,136June 1, 2002November 30, 2025DAVATZIKOS, CHRISTOSreporter.nih.gov
Molecularly-based outcome and toxicity prediction after radiotherapy for lung cancerNIHNational Cancer Institute2021 to 2024$2,463,397August 1, 2020April 30, 2026DIEHN, MAXIMILIANreporter.nih.gov
InHANCE: Imaging Innovation for Head And Neck Cancer Evaluation & Treatment DeliveryNIHNational Cancer Institute2025$2,457,127August 18, 2025July 31, 2030BROCK, KRISTYreporter.nih.gov
Optimization of MeV FLASH radiotherapy for normal tissue preservationNIHNational Cancer Institute2022 to 2025$2,453,320April 6, 2022March 31, 2027POGUE, BRIAN WILLIAMreporter.nih.gov
Alpha-Particle Emitter Radiopharmaceutical Therapy for Liver CancerNIHNational Cancer Institute2021 to 2024$2,446,660December 1, 2019November 30, 2024NEDROW, JESSIEreporter.nih.gov
Improved whole-brain spectroscopic MRI for radiation therapy planningNIHNational Cancer Institute2022 to 2025$2,436,201May 5, 2022April 30, 2027SHIM, HYUNSUKreporter.nih.gov
Prodrugs targeting norepinephrine transporter for dual-selective therapy of refractory neuroblastomaNIHNational Cancer Institute2021 to 2024$2,435,800July 1, 2020June 30, 2025CHORNY, MICHAELreporter.nih.gov
Ionization Detail - Biologically based treatment planning for particle therapy beyond LET-RBENIHNational Cancer Institute2022 to 2025$2,434,477September 1, 2022August 31, 2027FADDEGON, BRUCEreporter.nih.gov
NCTN Deep South Research ConsortiumNIHNational Cancer Institute2021 to 2025$2,431,217March 6, 2019February 28, 2026LEATH, CHARLES A.reporter.nih.gov
Precision imaging for risk stratification and personalized therapy of oropharyngeal cancerNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,430,433July 5, 2022March 31, 2027LI, RUIJIANGreporter.nih.gov
Personalized Cancer Therapy Guided by Photoacoustic Chemical Imaging (PACI) of Tumor Microenvironment (TME)NIHNational Cancer Institute2021 to 2025$2,429,748June 1, 2020May 31, 2027WANG, XUEDINGreporter.nih.gov
Surrogate biomarkers for assessing changes in pancreatic cancer tumor microenvironmentNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,423,859September 30, 2021June 30, 2026DOYLEY, MARVIN Mreporter.nih.gov
Drivers of metabolic plasticity promote radiation resistance in glioblastoma multiformeNIHNational Cancer Institute2021 to 2024$2,410,628July 6, 2020June 30, 2026VLASHI, ERINAreporter.nih.gov
Imaging and Targeted Auger Radiotherapy of High-Grade GliomaNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$2,407,488May 1, 2020January 31, 2025GARBOW, JOEL RICHARDreporter.nih.gov
Tumor-Selective Delivery Approaches for MedulloblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,405,248March 15, 2020December 31, 2024HELLER, DANIEL ALANreporter.nih.gov
Biomarkers of Response to Immuno-chemotherapy & oliGometastatic Hypofractionated radioTherapy (BRIGHT) for Lung Cancer: Synergy of PET/CT Imaging and Peripheral Blood AssaysNIHNational Cancer Institute2022 to 2025$2,404,930December 20, 2021November 30, 2026BOWEN, STEPHEN R.reporter.nih.gov
Development of polymeric synthetic biomaterial IP-001 to potentiate asystemic immunotherapy of hepatocellular carcinoma via thermal ablationNIHNational Cancer Institute2021 to 2024$2,400,000August 16, 2021August 31, 2025LAM, SIU KITreporter.nih.gov
SIRPant Technology for anti-Cancer ImmunityNIHNational Cancer Institute2021 to 2024$2,399,999September 22, 2021July 31, 2025MCCURLEY, NATHANAELreporter.nih.gov
The Impact of Obesity on Radiotherapy Anti-Tumor EffectsNIHNational Cancer Institute2022 to 2025$2,398,453March 1, 2022February 28, 2027MONJAZEB, ARTA MONIRreporter.nih.gov
Optical imaging to predict cell-level genetic heterogeneity and treatment sensitivity in colorectal cancerNIHNational Cancer Institute2021 to 2024$2,396,849June 8, 2018May 31, 2025DEMING, DUSTIN Areporter.nih.gov
Urine based circulating tumor DNA analysisNIHNational Cancer Institute2021 to 2025$2,390,011July 1, 2021June 30, 2026LAUTENSCHLAEGER, TIMreporter.nih.gov
Preclinical assessment of a novel compound for treating radiation-induced oral mucositisNIHNational Institute of Dental & Craniofacial Research2024 to 2025$2,382,478September 5, 2024August 31, 2026LLOYD, COLTON JOSEPHreporter.nih.gov
Ultra-Low Count Quantitative SPECT for Alpha-Particle TherapiesNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,381,642September 30, 2022June 30, 2027JHA, ABHINAV Kreporter.nih.gov
Functional Characterization and Development of Therapeutic Paradigms for DNA Damage Repair (DDR)-deficient Lethal Prostate CancerNIHNational Cancer Institute2023 to 2025$2,380,224April 1, 2023March 31, 2028CHAKRABORTY, GOUTAMreporter.nih.gov
Bringing Capacity for Theranostic Dosimetry Planning to the Nuclear Medicine ClinicNIHNational Cancer Institute2021 to 2024$2,379,250June 1, 2020May 31, 2026DEWARAJA, YUNI Kreporter.nih.gov
Tumor-penetrating nano-theranostics for image-guided interventions in spontaneous feline head and neck cancerNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,375,504July 1, 2020April 30, 2026LI, YUANPEIreporter.nih.gov
PHASE I FAST TRACK TOPIC 461 CONFORMABLE SCINTILLATOR ARRAY FOR IN VIVO DOSIMETRY DURING RTNIHNational Cancer Institute2024 to 2025$2,372,276September 16, 2025September 15, 2027BRUZA, PETRreporter.nih.gov
MELT: Modulation of PSMA Expression for Lutetium TherapyNIHNational Cancer Institute2021 to 2025$2,363,818July 1, 2019June 30, 2026HOPE, THOMAS Areporter.nih.gov
In situ cancer cell specific biomineralization to overcome nanoparticle delivery barriers and sensitize pancreatic cancer to radiotherapyNIHNational Cancer Institute2022 to 2025$2,362,124August 2, 2022July 31, 2027SOKOLOV, KONSTANTIN Vreporter.nih.gov
Translation of a Bismuth-Gadolinium Nanoparticle for MR-guided Radiation TherapyNIHNational Cancer Institute2021 to 2024$2,352,523March 1, 2020February 28, 2026BERBECO, ROSS I.reporter.nih.gov
Theranostic for gastric cancerNIHNational Cancer Institute2023 to 2025$2,346,556September 11, 2023August 31, 2027HUMBLET, VALERIEreporter.nih.gov
Tumor-associated macrophages in vasogenic cerebral edema in brain tumorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,339,629September 30, 2017August 31, 2027HAMBARDZUMYAN, DOLORESreporter.nih.gov
A tissue viability imaging biomarker for use in non-invasive breast cancer therapyNIHNational Cancer Institute2022 to 2025$2,335,729February 10, 2022January 31, 2027PAYNE, ALLISONreporter.nih.gov
Metabolic Regulation of Glioblastoma EpitranscriptomicsNIHNational Cancer Institute2022 to 2025$2,327,158July 7, 2022June 30, 2027AGNIHOTRI, SAMEERreporter.nih.gov
EPR scanner for tumor oximetry in the clinicNIHNational Cancer Institute2023 to 2025$2,325,258January 1, 2023December 31, 2027KUPPUSAMY, PERIANNANreporter.nih.gov
A novel flat-panel detector for advanced on-board radiation therapy imagingNIHNational Cancer Institute2021 to 2024$2,324,892September 1, 2014June 30, 2025BERBECO, ROSS I.reporter.nih.gov
Bottom-Up Assembly of Functional Salivary Gland TissuesNIHNational Institute of Dental & Craniofacial Research2021 to 2025$2,324,071May 1, 2021January 31, 2027JIA, XINQIAOreporter.nih.gov
TRANSCRANIAL FUS THERAPY WITH CLOSED-LOOP US IMAGE GUIDANCE AND CIRCULATINGNIHNational Cancer Institute2021 to 2025$2,322,901August 1, 2020April 30, 2027ARVANITIS, KONSTANTINOS-COSTASreporter.nih.gov
Laser speckle flowgraphy as early indicator of microvasculopathy in radiation-induced vision lossNIHNational Eye Institute2021 to 2024$2,314,921May 1, 2020April 30, 2026GRUMBACH, ISABELLA MARIAreporter.nih.gov
Improving efficacy of radioiodine treatment of thyroid cancerNIHNational Cancer Institute2021 to 2025$2,314,655April 1, 2021March 31, 2026FAGIN, JAMES Areporter.nih.gov
TOPAS - nBio, a Monte Carlo tool for radiation biology researchNIHNational Cancer Institute2021 to 2024$2,314,349April 1, 2015January 31, 2026SCHUEMANN, JAN PATRICK OSCARreporter.nih.gov
Glial immune signaling in radiation-induced brain injuryNIHNational Cancer Institute2021 to 2025$2,293,007September 1, 2021August 31, 2026ACHARYA, MUNJAL Mreporter.nih.gov
PET Enabled Y-90 Microspheres for Radioembolization of Liver TumorsNIHNational Cancer Institute2021 to 2022$2,286,178August 1, 2012July 31, 2024PENG, YONGREN BENJAMINreporter.nih.gov
Determining the optimal ion and fractionation scheme for the treatment of GBM in a comprehensive human organoid modelNIHNational Cancer Institute2021 to 2025$2,268,156March 1, 2021February 28, 2026GROSSHANS, DAVID Rreporter.nih.gov
Aligning financial incentives to promote rational use of active surveillance for prostate cancerNIHNational Cancer Institute2022 to 2025$2,252,166April 1, 2022March 31, 2027SHAHINIAN, VAHAKN Breporter.nih.gov
Reducing cardiac toxicity with deep learning and MRI-guided radiation therapyNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,238,763August 23, 2021July 31, 2026GLIDE-HURST, CARRI KAYEreporter.nih.gov
Multiparametric Magnetic Resonance Imaging as a Novel Approach to Brachytherapy for Cervical CancerNIHNational Cancer Institute2021 to 2024$2,207,873March 1, 2020February 28, 2026VISWANATHAN, AKILAreporter.nih.gov
Improving pediatric brain tumor treatments using FLASH radiotherapyNIHNational Cancer Institute2021 to 2025$2,200,868July 1, 2021June 30, 2027LIMOLI, CHARLESreporter.nih.gov
Connectivity mapping identified novel combination therapy for glioblastomaNIHNational Cancer Institute2022 to 2025$2,198,374September 1, 2025August 31, 2027SHONKA, NICOLEreporter.nih.gov
The Impact of Biologic Aging on Immunity-Related Cervical Cancer Outcome Disparities Among Women Living with HIV in ZambiaNIHNational Cancer Institute2023 to 2025$2,188,094September 19, 2023August 31, 2028LIN, LILIE LEMINGreporter.nih.gov
Combination Radiopharmaceutical Therapy and External Beam RadiotherapyNIHNational Cancer Institute2021 to 2025$2,186,356September 3, 2020June 30, 2027HOBBS, ROBERT FRANCOISreporter.nih.gov
MiR-152/PKM2/SLC7A5 axis in breast cancer development, chemo- and radiation-treatment responseNIHNational Cancer Institute2022 to 2025$2,185,830April 1, 2022March 31, 2027HE, JUNreporter.nih.gov
Artificial Intelligence-Based Quality Assurance for Online Adaptive RadiotherapyNIHNational Cancer Institute2022 to 2025$2,175,003March 9, 2022August 31, 2027JIANG, STEVE BINreporter.nih.gov
lncRNA regulation of glioblastoma progression and therapeutic resistanceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,168,484December 1, 2021November 30, 2026YU, JENNIFER Sreporter.nih.gov
Biological Comparisons Among Three Derivative Models of Glioma Patient Cancers Under Microenvironmental StressNIHNational Cancer Institute2021 to 2022$2,160,078September 17, 2018August 31, 2024WILLEY, CHRISTOPHER Dreporter.nih.gov
Interrogating the in vivo pharmacokinetics of armored CARs with radiohapten captureNIHNational Cancer Institute2021 to 2024$2,149,252July 7, 2021January 1, 2025KREBS, SIMONEreporter.nih.gov
Cherenkov imaging incorporating 3D surface imaging for TSETNIHNational Cancer Institute2022 to 2025$2,147,468September 1, 2022August 31, 2027ZHU, TIMOTHY C.reporter.nih.gov
Biomarker Approach to Screening for the early detection of HPV-related Oropharyngeal Cancer (BASH OPC)NIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,145,712September 4, 2023June 30, 2028GIULIANO, ANNA R.reporter.nih.gov
The Thromboxane-Prostanoid Receptor in Radiation-Induced Pulmonary FibrosisNIHNational Cancer Institute2023 to 2025$2,141,378August 22, 2023July 31, 2028WEST, JAMES Dreporter.nih.gov
Quantitative imaging phenotypic classifier for distinguishing radiation effects from tumor recurrence in GlioblastomaNIHNational Cancer Institute2022 to 2025$2,135,258June 30, 2022May 31, 2028TIWARI, PALLAVIreporter.nih.gov
Leveraging deep learning for markerless motion management in radiation therapyNIHNational Cancer Institute2021 to 2025$2,135,070April 1, 2021March 31, 2026XING, LEIreporter.nih.gov
Use of CTEP portfolio compounds to counteract phenotype conversion in GBMNIHNational Cancer Institute2022 to 2025$2,134,457January 1, 2022December 31, 2026PAJONK, FRANKreporter.nih.gov
Targeting Nucleotide Excision Repair Deficiency to Improve Bladder Sparing Treatment for Muscle Invasive Bladder CancerNIHNational Cancer Institute2022 to 2025$2,132,323September 22, 2022August 31, 2027MOUW, KENT Wreporter.nih.gov
CAUSAL: Cohort to Augment the Understanding of Sarcoma Survivorship Across the LifespanNIHNational Cancer Institute2021 to 2022$2,127,132September 22, 2021August 31, 2023FRIEDMAN, DEBRA L.reporter.nih.gov
Continuous, Non-Invasive Optical Monitoring of Circulating Tumor Cell-Mediated Metastasis in Awake MiceNIHNational Cancer Institute2022 to 2025$2,117,767March 3, 2022February 28, 2027NIEDRE, MARK JONATHANreporter.nih.gov
Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Patients with CancerNIHNational Cancer Institute2021 to 2024$2,117,051July 1, 2019June 30, 2025MAZANEC, SUSANreporter.nih.gov
Myeloid cell-selective, oligonucleotide-based STAT3 inhibition combined with total marrow and lymphoid irradiation for immunotherapy of acute myeloid leukemiaNIHNational Cancer Institute2023 to 2025$2,114,878July 19, 2023June 30, 2028KORTYLEWSKI, MARCINreporter.nih.gov
AC-225 Imaging R01 TransferNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$2,114,545September 30, 2022June 30, 2027CARAVACA, JAVIERreporter.nih.gov
Advancing Cancer Therapy through Groundbreaking Research in Radiation BiologyNIHNational Cancer Institute2023 to 2025$2,114,155January 16, 2016August 31, 2029KIRSCH, DAVID GUYreporter.nih.gov
Advancing CAR T cell therapy for solid tumorsNIHOffice of the Director, National Institutes of Health2021 to 2025$2,112,916September 14, 2021August 31, 2026AHMED, JALALreporter.nih.gov
Quantitative Imaging Biomarker Prospective Validation of Dynamic Contrast-Enhanced MRI as a Metric of Orodental Injury After Radiotherapy (QI-ProVE-MRI)NIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,109,951April 1, 2023January 31, 2028LAI, STEPHEN Yreporter.nih.gov
An ultra-high (FLASH) dose rate x-ray cabinet system for pre-clinical laboratory radiation researchNIHNational Cancer Institute2021 to 2024$2,107,434August 1, 2021July 31, 2025REZAEE, MOHAMMADreporter.nih.gov
Elucidating the role of DNAPKcs in chromosomal break end joining and clastogen resistanceNIHNational Cancer Institute2021 to 2025$2,105,577July 1, 2021June 30, 2027STARK, JEREMY MICHAELreporter.nih.gov
Determine genotypic, phenotypic and evolutionary trajectories of treatment resistance to radiotherapy.NIHNational Cancer Institute2025$2,105,127September 23, 2025August 31, 2029GOPAL, PRIYANKAreporter.nih.gov
TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumorsNIHNational Cancer Institute2023 to 2025$2,103,321June 9, 2023May 31, 2028BRACKETT, CRAIG M.reporter.nih.gov
Novel roles of PCSK9 in regulating the tumor immune microenvironment during radiotherapyNIHNational Cancer Institute2022 to 2025$2,102,853August 1, 2022July 31, 2027ZHANG, JENNIFER YUNYANreporter.nih.gov
A Type I Hybrid Effectiveness-Implementation Trial to Evaluate a Navigation-Based Multilevel Intervention to Decrease Delays Starting Adjuvant Therapy Among Patients with Head and Neck CancerNIHNational Cancer Institute2023 to 2025$2,097,727August 1, 2023July 31, 2028GRABOYES, EVAN MICHAELreporter.nih.gov
Imaging and Dosimetry of Yttrium-90 for Personalized Cancer TreatmentNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$2,097,012September 15, 2016April 30, 2026DEWARAJA, YUNI Kreporter.nih.gov
Novel Functional Anatomic and Biomarker Indices of Radiation-Induced Female Sexual Toxicities in a Multi-Center CohortNIHOffice of the Director, National Institutes of Health2021 to 2025$2,095,968September 14, 2021August 31, 2026MARSHALL, DEBORAH CATHERINEreporter.nih.gov
Lymph node-targeted multistage chemoimmunotherapy for lymphomaNIHNational Cancer Institute2021 to 2024$2,094,096April 1, 2020March 31, 2026THOMAS, SUSAN NAPIERreporter.nih.gov
Comparative Effectiveness of Surgery vs Stereotactic Radiation Therapy for Stage I Lung CancerNIHNational Cancer Institute2022 to 2025$2,091,593February 24, 2022January 31, 2028KOZOWER, BENJAMIN Dreporter.nih.gov
Bioinformatic-Chemical Approach to Credential Molecular Targets to Combat Rapid Chemo-Radiation Resistance in SCLCNIHNational Cancer Institute2021 to 2022$2,087,996September 3, 2018August 31, 2024HANN, CHRISTINE L.reporter.nih.gov
Multimodal Imaging and Therapy of Ovarian CancerNIHNational Cancer Institute2021 to 2025$2,083,778August 20, 2021July 31, 2027KUNDRA, VIKASreporter.nih.gov
An AI-enabled Digital Pathology Platform for Multi-Cancer Diagnosis, Prognosis and Prediction of Therapeutic BenefitNIHNational Cancer Institute2022 to 2025$2,081,138September 5, 2022August 31, 2027MADABHUSHI, ANANTreporter.nih.gov
A PET/CT scanner for guiding treatment of head and neck cancerNIHNational Cancer Institute2021 to 2025$2,079,022May 8, 2020April 30, 2027RAYLMAN, RAYMOND ROBERTreporter.nih.gov
Biomarkers, mechanisms and modulation of oxidative stress associated risk factors in carcinogenesisNIHOffice of the Director, National Institutes of Health2022 to 2025$2,065,432September 14, 2022December 31, 2025LI, YUN ROSEreporter.nih.gov
Inhibition of Radiation-Induced Coronary Microvascular DiseaseNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,050,609January 15, 2021December 31, 2026POKHAREL, SARASWATIreporter.nih.gov
Transformable Theranostics for imaging-guided interventions in head and neck squamous cell carcinomaNIHNational Cancer Institute2021 to 2024$2,050,000September 1, 2019February 28, 2026LIN, TZU-YINreporter.nih.gov
Patient tailored near real-time image-based treatment for interstitial PDT of Inoperable Cancer with Airway Obstruction - Phase IIaNIHNational Cancer Institute2021 to 2022$2,050,000August 11, 2021July 31, 2025POTASEK, MARYreporter.nih.gov
Cellular plasticity and regeneration afterradiation damage in DrosophilaNIHNational Institute of General Medical Sciences2021 to 2025$2,044,972January 1, 2019January 31, 2029SU, TIN TINreporter.nih.gov
Salivary gland response to Desert hedgehog signaling as an antidote to damage from therapeutic radiationNIHNational Institute of Dental & Craniofacial Research2022 to 2025$2,039,007March 15, 2022January 31, 2027BEACHY, PHILIP Areporter.nih.gov
Exploiting cell fate transition to overcome radiation resistance in glioblastomaNIHNational Cancer Institute2023 to 2025$2,038,414July 28, 2023June 30, 2028SULMAN, ERIKreporter.nih.gov
Targeting the CD73-adenosinergic pathway in head and neck cancerNIHNational Institute of Dental & Craniofacial Research2023 to 2025$2,031,588September 1, 2023May 31, 2028CUI, YANreporter.nih.gov
Nanoparticle-based Intraperitoneal Delivery of Combined Chemo-radiotherapy for Treatment of Ovarian Cancer MetastasesNIHNational Cancer Institute2022 to 2023$2,025,186September 11, 2019July 31, 2025JAY, MICHAELreporter.nih.gov
Development of a prototype clinical theranostic platform combining Magnetic Particle Imaging (MPI) and Magnetic Fluid Hyperthermia (MFH) for the treatment of brain tumorsNIHNational Cancer Institute2023 to 2024$2,023,904July 1, 2023June 30, 2025GOODWILL, PATRICKreporter.nih.gov
Lineage Plasticity, due to Disruption of MnSOD Biology, drives resistance to Ionizing Radiation / Androgen Deprivation TherapyNIHNational Cancer Institute2021 to 2025$2,021,205April 9, 2021March 31, 2027GIUS, DAVIDreporter.nih.gov
Regulation of Tumor Oxygenation by BACH1 in Breast CancerNIHNational Cancer Institute2022 to 2025$2,019,611September 1, 2022August 31, 2027ROSNER, MARSHA Rreporter.nih.gov
Elucidating the Roles of RNA m6A readers Y1 and Y2 in radiation-induced immunity and immunotherapyNIHNational Cancer Institute2021 to 2025$2,018,928July 1, 2021June 30, 2026WEICHSELBAUM, RALPH Rreporter.nih.gov
Intratumoral Cytokine Immunotherapy Studies in Companion Canine Cancer ModelsNIHNational Cancer Institute2022 to 2025$2,016,960April 12, 2022March 31, 2026WITTRUP, KARL DANEreporter.nih.gov
Uncover the role of H3.3-G343R mutation in shaping the DNA damage response, anti-tumor immunity and mechanisms of resistance in glioma.NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,006,629January 15, 2022December 31, 2026CASTRO, MARIA Greporter.nih.gov
Immunoregulatory role of lung-resident club cell factors in lung cancerNIHNational Cancer Institute2023 to 2025$2,003,505February 1, 2023January 31, 2028MITTAL, VIVEKreporter.nih.gov
BMX-001 as a Therapeutic Agent for Treatment of High-Grade GliomasNIHNational Cancer Institute2021 to 2022$2,001,625September 18, 2015May 31, 2023CRAPO, JAMES Dreporter.nih.gov
Development of an ultra-high dose rate rotational linac for FLASH RadiotherapyNIHNational Cancer Institute2023 to 2025$2,000,108March 15, 2021February 28, 2026SHENG, KEreporter.nih.gov
Development of a Commercial-Ready Kit for CTT1403, a Novel PSMA-Targeted RadiotherapyNIHNational Cancer Institute2021 to 2022$2,000,000September 20, 2021August 31, 2024BOMBA, HUNTER NICOLEreporter.nih.gov
eNamptorTM: A Humanized mAb To Reduce the Severity of Radiation Pneumonitis and FibrosisNIHNational Heart, Lung, and Blood Institute2021 to 2022$2,000,000June 1, 2020May 31, 2023GARCIA, JOE G. N.reporter.nih.gov
Ultra-fast imaging for the safe delivery of electron FLASH radiation therapyNIHNational Cancer Institute2022 to 2023$2,000,000September 16, 2021August 31, 2025BRUZA, PETRreporter.nih.gov
Topic #402: Artificial Intelligence-Aided Imaging for Cancer Prevention, Diagnosis, and MonitoringProject Title: An Interpretable Physician-In-The-Loop Al-Aided Software For Tumor Surveillance In BrNIHNational Cancer Institute2022$2,000,000September 15, 2022September 14, 2024RAHAL, HAYATreporter.nih.gov
Biograph Vision 600 PET/CT systemNIHOffice of the Director, National Institutes of Health2023$2,000,000May 1, 2023April 30, 2025SCOTT, PETER JAMES HENRYreporter.nih.gov
SBIR PHASE II, TOPIC 431: AUTOMATIC TREATMENT PLANNING OF CERVICAL CANCER HIGH-DOSE RATE BRACHYTHERPAY FOR LOW-RESOURCE SETTINGS.NIHNational Cancer Institute2024$2,000,000September 4, 2024September 3, 2026GHIMIRE, KANCHANreporter.nih.gov
A Phase 1b, Open-Label, Study of a Novel Targeted Radiotherapy in Children, Adolescents and Young Adults with Inoperable Relapsed or Refractory High Grade GliomaNIHNational Cancer Institute2022 to 2023$1,999,998September 16, 2022June 30, 2024REILLY, LAURENCEreporter.nih.gov
Everyday Use of Optical Cherenkov Imaging Identifies Adverse Events and Opportunities for Improved Radiation TreatmentNIHNational Cancer Institute2021 to 2022$1,999,995August 24, 2021July 31, 2024WARE, WILLIAMreporter.nih.gov
FY24 SBIR PHASE IITOPIC NO. 434PROJECT TITLE: ULTRA-RAID RF-BASED BEAM MONITOR FOR REAL-TIME FLASH BEAM CONTROLNIHNational Cancer Institute2024$1,999,956September 16, 2024September 15, 2026TOUFEXIS, FILIPPOSreporter.nih.gov
Targeted alpha-emitter therapy of patients with PRRT refractory neuroendocrine tumorsNIHNational Cancer Institute2021 to 2022$1,999,943September 7, 2021February 29, 2024TWOROWSKA, IZABELAreporter.nih.gov
SBIR TOPIC 434 PHASE II: DEVELOPMENT OF MULTILAYER STRIP ION CHAMBER DEVICE FOR THE MEASUREMENT OF FLASH-RT BEAMSPERIOD OF PERFORMANCE: 9/16/24-9/15/26NIHNational Cancer Institute2024$1,999,930September 16, 2024September 15, 2026JIANG, HAOreporter.nih.gov
A turnkey research platform to accelerate clinical translation of targeted immune-modulation enhanced therapiesNIHNational Cancer Institute2021 to 2022$1,999,441September 11, 2019July 31, 2025GESSNER, RYANreporter.nih.gov
An Open-Labeled, Single Arm Phase 2 Efficacy and Safety Study of REM-001 Photodynamic Therapy (PDT) for Treatment of Cutaneous Metastatic Breast Cancer (CMBC)NIHNational Cancer Institute2023 to 2024$1,999,439July 1, 2023June 30, 2025BROWN, DENNISreporter.nih.gov
FY24 SBIR Phase 2 RD Contract - Topic 431 Light Research, Inc.NIHNational Cancer Institute2024$1,998,978September 16, 2024September 15, 2026WILDER-SMITH, PETRAreporter.nih.gov
SBIR TOPIC 401 PHASE II:NIHNational Cancer Institute2023$1,998,128September 18, 2023September 17, 2025GHAZI, PH.D., PEYMONreporter.nih.gov
DoseRT™ : A Non-Contact Optical Patient and Beam Dosimetry System for Continuous in vivo Radiotherapy VerificationNIHNational Cancer Institute2024 to 2025$1,997,948August 1, 2018May 31, 2027WARE, WILLIAMreporter.nih.gov
Cancer Cell Intrinsic Interferon-I pathway Activation by Fractionated RadiationNIHNational Cancer Institute2022 to 2025$1,997,536January 19, 2016August 31, 2027DEMARIA, SANDRAreporter.nih.gov
Improving allocation of scarce medical physics resources through a novel, comprehensive quality assurance device.NIHNational Cancer Institute2024 to 2025$1,997,481September 1, 2024August 31, 2027MOLLOY, JANELLE ARLENEreporter.nih.gov
PET imaging of radiation induced lung injuryNIHNational Cancer Institute2022 to 2023$1,996,724May 4, 2020May 31, 2025HUMBLET, VALERIEreporter.nih.gov
Integrating circulating tumor DNA assay and protein-based MRI to accurately monitor glioma therapyNIHNational Cancer Institute2023 to 2025$1,996,509July 1, 2023June 30, 2028JIANG, SHANSHANreporter.nih.gov
Targeted radiation and immunocytokine therapy for CEA positive malignanciesNIHNational Cancer Institute2023 to 2025$1,994,976September 21, 2023August 31, 2028SHIVELY, JOHN ERNESTreporter.nih.gov
An Open-Label, Multicenter, Phase 2/3 Efficacy and Safety Study of a targeted radiotherapy in Patients with Relapsed or Refractory Waldenstroms MacroglobulinemiaNIHNational Cancer Institute2021 to 2023$1,994,489September 1, 2021August 31, 2024LONGCOR, JARRODreporter.nih.gov
Academic-Industry Partnership for the Translation of a 4D in vivo Dosimetry Approach for Radiation TherapyNIHNational Cancer Institute2021 to 2025$1,991,186September 20, 2019August 31, 2026XIANG, SHAWN LIANGZHONGreporter.nih.gov
Torch Recon: An Innovative Reconstruction Software for Increased Throughput and Improved Low-Count Quantitative SPECT ImagingNIHNational Cancer Institute2024 to 2025$1,989,181September 19, 2024August 31, 2026WICKRE, PAULreporter.nih.gov
Optimizing immunoradiotherapy for HNSCCNIHNational Cancer Institute2023 to 2025$1,988,993September 25, 2023August 31, 2028CALIFANO, JOSEPH Areporter.nih.gov
Comprehensive Assessment of Cancer Theranostics ResponseNIHNational Cancer Institute2023 to 2024$1,985,840September 22, 2023August 31, 2025PERK, TIMOTHYreporter.nih.gov
Breast Cancer Brain Metastasis Therapy by Focused Ultrasound-Guided Control of HER2 CAR T cellsNIHNational Cancer Institute2023 to 2025$1,982,412June 8, 2023May 31, 2028ARVANITIS, KONSTANTINOS-COSTASreporter.nih.gov
Thermoacoustic Range Verification During Delivery of a Clinical Plan by a Synchrocyclotron: transition from research prototype to turnkey clinical deviceNIHNational Cancer Institute2022 to 2024$1,981,853August 1, 2019March 31, 2026PATCH, SARAH KATHRYNreporter.nih.gov
SBIR TOPIC 434 PHASE II: ULTRA-FAST DOSE RATE (FLASH) RADIATION DETECTORS AND SAFETY SYSTEMSPERIOD OF PERFORMANCE: 16 SEPTEMBER 2024 - 15 SEPTEMBER 2026FIRM FIXED PRICENIHNational Cancer Institute2024$1,980,915September 16, 2024September 15, 2026BOISSEAU, RAYMOND Preporter.nih.gov
Focused Ultrasound Regimens that Synergize with Melanoma ImmunotherapyNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,973,381July 1, 2020March 31, 2025PRICE, RICHARD J.reporter.nih.gov
Systematic dissection of function and mechanism of long non-coding RNAs in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,972,350April 15, 2021February 28, 2027CHEN, YIWENreporter.nih.gov
Nanoscale Metal-Organic Frameworks Enable Radiotherapy-Radiodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Generate Tumor Vaccines and Potentiate Immunotherapy of Head and Neck CancersNIHNational Cancer Institute2021 to 2024$1,972,047July 1, 2020June 30, 2025LIN, WENBINreporter.nih.gov
Detection, Radiosensitization and Theranostic Targeting of Metastatic Breast Cancer by PTPmuNIHNational Cancer Institute2023 to 2025$1,971,026December 1, 2022November 30, 2027BRADY-KALNAY, SUSANN Mreporter.nih.gov
Optimizing theranostic radiopharmaceutical therapy to combat resistance to PARP inhibition in advanced ovarian cancerNIHNational Cancer Institute2023 to 2025$1,970,274May 31, 2023April 30, 2028FARWELL, MICHAEL DAVIDreporter.nih.gov
Cellular phenotypic heterogeneity and resistance to radiotherapy in pancreatic adenocarcinomaNIHOffice of the Director, National Institutes of Health2021 to 2025$1,968,750September 22, 2021August 31, 2026PITTER, KENNETH Lreporter.nih.gov
Potentiating a systemic antitumor response by interstitial localized ablative immunotherapy to synergize with immune checkpoint therapy for metastatic pancreatic tumorsNIHNational Cancer Institute2022 to 2025$1,966,506April 1, 2022March 31, 2027CHEN, WEI R.reporter.nih.gov
STING-dependent Intestinal Regeneration upon Radiation InjuryNIHNational Cancer Institute2023 to 2025$1,965,866September 1, 2023August 31, 2027YU, JIANreporter.nih.gov
The development of novel radiation-sensitizer based on ultra-small carbon dotsNIHNational Cancer Institute2021 to 2024$1,960,035July 15, 2020June 30, 2026LI, ZIBOreporter.nih.gov
Systematic evaluation of toxicity and therapeutic efficacy in CD46 directed radioligand therapyNIHNational Cancer Institute2023 to 2025$1,959,827May 1, 2023April 30, 2028FLAVELL, ROBERT RICHARDreporter.nih.gov
Therapeutic resistance and aggressive malignancy in glioblastomas: the contribution of GTP metabolism through regulation by IMPDH2NIHNational Cancer Institute2021 to 2025$1,959,151July 7, 2021June 30, 2027SASAKI, ATSUOreporter.nih.gov
Inhibition of wild-type IDH1 as a ferroptosis-inducing therapeutic approach for the treatment of malignant glioma.NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,952,697September 1, 2022June 30, 2027STEGH, ALEXANDER H.reporter.nih.gov
Image-guided dosimetry-based alpha particle therapy for neuroblastoma.NIHNational Cancer Institute2022 to 2023$1,951,675August 4, 2022July 31, 2025SCHULTZ, MICHAEL KINGreporter.nih.gov
Mechanisms of fasting-induced radioprotection of small intestinal epithelial cellsNIHNational Cancer Institute2023 to 2025$1,951,482June 1, 2023May 31, 2028PIWNICA-WORMS, HELEN Mreporter.nih.gov
A single-arm phase II study to evaluate the safety and efficacy of combination systematic chemotherapy and multiple rounds of endoscopic ultrasound-guided radiofrequency ablation in pancreatic cancerNIHNational Cancer Institute2023 to 2025$1,948,805July 1, 2023June 30, 2028THOSANI, NIRAVreporter.nih.gov
A Novel Recombinant Protein for Mitigating Acute Radiation InjuryNIHNational Institute of Allergy and Infectious Diseases2021 to 2022$1,948,766June 10, 2014March 31, 2024CHAUNG, WAYNEreporter.nih.gov
A Physiologic Adaptive Radiation Therapy Pipeline for Glioblastoma by Daily Multiparametric MRI and Machine LearningNIHNational Cancer Institute2022 to 2025$1,941,434March 3, 2022August 1, 2025MELLON, ERIC ALBERTreporter.nih.gov
Early response to radiotherapy and immunotherapy in rectal cancer: an integrated molecular, cellular, and spatial approachNIHNational Cancer Institute2023 to 2025$1,938,556August 1, 2023July 31, 2028AGUILERA, TODD Areporter.nih.gov
The role of ATRX mutation in the epigenetic dysregulation of cell cycle in pediatric high-grade gliomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,938,300July 1, 2021June 30, 2026KOSCHMANN, CARL Jreporter.nih.gov
Targeting ferroptosis in radioresistance in lung cancer: mechanisms and preclinical translationNIHNational Cancer Institute2021 to 2025$1,931,122December 7, 2020November 30, 2025GAN, BOYIreporter.nih.gov
Advanced C-arm imaging platform for histotripsy treatment of liver tumorsNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$1,929,996January 1, 2022November 30, 2026LAESEKE, PAUL Freporter.nih.gov
Safer lung cancer radiotherapy delivery using novel artificial intelligence methodsNIHNational Cancer Institute2022 to 2025$1,925,783June 15, 2022May 31, 2027VEERARAGHAVAN, HARINIreporter.nih.gov
Combining receptor-targeted alpha particle therapy and immunotherapy to achieve complete responses in metastatic melanomaNIHNational Cancer Institute2022 to 2023$1,924,767June 1, 2019May 31, 2025SCHULTZ, MICHAEL KINGreporter.nih.gov
Combined radiation acoustics and ultrasound imaging for real-time guidance in radiotherapyNIHNational Cancer Institute2021 to 2024$1,923,937August 1, 2023July 31, 2025EL NAQA, ISSAM M.reporter.nih.gov
Improving Patient-Important Outcomes with Testosterone Replacement in Hypogonadal Men with a Prior History of CancerNIHNational Cancer Institute2022 to 2025$1,917,613May 8, 2019April 30, 2027GARCIA, JOSE M.reporter.nih.gov
Multi-Task MR Simulation for Abdominal Radiation Treatment PlanningNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,911,806April 1, 2021March 31, 2025FAN, ZHAOYANGreporter.nih.gov
A Multifaceted Radiomics Model to Predict Cervical Lymph Node Metastasis for Involved Nodal Radiation TherapyNIHNational Cancer Institute2022 to 2025$1,909,407July 1, 2022June 30, 2027WANG, JINGreporter.nih.gov
OST Inhibition in NSCLCNIHNational Cancer Institute2021 to 2024$1,907,996June 1, 2020May 31, 2025CONTESSA, JOSEPH Nreporter.nih.gov
Machine learning accelerated on-line adaptive replanningNIHNational Cancer Institute2021 to 2024$1,907,890April 1, 2020March 31, 2026PAULSON, ERIC Sreporter.nih.gov
Targeting Mitochondrial Redox Capacity to Overcome Cancer Subtype that Regrowth After RadiationNIHNational Cancer Institute2021 to 2025$1,906,181April 1, 2021March 31, 2027CHAISWING, LUKSANAreporter.nih.gov
Analysis of high dimensional genomic dataset to reveal mechanistic insights on divergent outcomes of head and neck cancer using system biology modeling coupled with experimental validationNIHNational Institute of Dental & Craniofacial Research2025$1,899,042September 19, 2025September 18, 2028WANG, JING HONGreporter.nih.gov
Developing whole-body computational phantoms for blood dosimetry to model the impact of radiation on the immune systemNIHNational Cancer Institute2021 to 2024$1,897,702July 13, 2020June 30, 2025PAGANETTI, HARALDreporter.nih.gov
Enhancement of tumor radiation response by ultrasound-driven nanobubble stimulationNIHNational Cancer Institute2021 to 2024$1,889,708August 11, 2021July 31, 2026EXNER, AGATA Areporter.nih.gov
Development of a Novel Lung Function Imaging Modality for comprehensive management of lung cancerNIHNational Cancer Institute2021 to 2025$1,887,371May 29, 2021December 31, 2026VINOGRADSKIY, YEVGENIYreporter.nih.gov
Ultrafast and Precise External Beam Monitor for FLASH and Other Advanced Radiation Therapy ModalitiesNIHNational Cancer Institute2021 to 2023$1,887,301September 16, 2021August 31, 2025FRIEDMAN, PETER Sreporter.nih.gov
Nanotherapeutic enhancement of interstitial thermal therapy for glioblastomaNIHNational Cancer Institute2023 to 2025$1,886,274December 1, 2022November 30, 2027WOODWORTH, GRAEME Freporter.nih.gov
Elucidating the Role of Perivascular Niche in Glioblastoma Invasion and Therapeutic Resistance at Single Cell Resolution using Biomimetic Tumor Microenvironment ModelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,884,981September 15, 2021July 31, 2027NIKKHAH, MEHDIreporter.nih.gov
Developmental regulation of apoptosis as a modifiable driver of radiotherapy-induced neurocognitive impairment in pediatric patientsNIHNational Cancer Institute2021 to 2025$1,878,585March 9, 2020February 28, 2027SAROSIEK, KRISTOPHER ANDREWreporter.nih.gov
SUPPLEMENTAL WORK-SARS-COV-2NIHNational Institute of Allergy and Infectious Diseases2021$1,872,652April 1, 2019July 31, 2022KAYTOR, MICHAELreporter.nih.gov
Radiation-induced vascular reprogramming in glioblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,870,651December 15, 2021November 30, 2026KORNBLUM, HARLEY IANreporter.nih.gov
A clinical tool for automated detection and delineation of intracranial metastases from MRINIHNational Cancer Institute2021 to 2025$1,866,251August 1, 2021July 31, 2027CAO, YUEreporter.nih.gov
Neoadjuvant immunoradiotherapy for HPV mediated oropharynx cancerNIHNational Cancer Institute2023 to 2025$1,854,023September 18, 2023July 31, 2028CALIFANO, JOSEPH Areporter.nih.gov
Impact of Host NF-kB Signaling in Radiation TherapyNIHNational Cancer Institute2021 to 2025$1,848,396July 1, 2021June 30, 2026MIYAMOTO, SHIGEKIreporter.nih.gov
Optimizing radiation therapy through the manipulation of glutamine metabolismNIHNational Cancer Institute2022 to 2025$1,844,128September 16, 2014August 31, 2027SCHWARZ, JULIE KRISTINAreporter.nih.gov
Improving Health Utilization and Quality of Life in Head and Neck Cancer Patients Undergoing Chemoradiation and their Family CaregiversNIHNational Cancer Institute2021 to 2025$1,838,578September 15, 2020June 30, 2026MILBURY, KATHRINreporter.nih.gov
Oral Cavity Quantitative Histomorphometric Risk Classifier (OHbIC) in Oral Cavity Squamous Cell Carcinoma (OC-SCC)NIHNational Cancer Institute2023 to 2025$1,835,154December 30, 2020August 31, 2026MADABHUSHI, ANANTreporter.nih.gov
Ultra-sensitive Singlet Oxygen Dosimeter for Skin Cancer Treatment and PreventionNIHNational Cancer Institute2021 to 2022$1,832,173July 1, 2021June 30, 2025ZHAO, YOUBOreporter.nih.gov
Radiation-Induced Fibrosis and Co-occurring Adverse Treatment-Related Effects in Head and Neck Cancer SurvivorsNIHNational Cancer Institute2023 to 2025$1,830,251July 1, 2023June 30, 2028NILSEN, MARCI LEEreporter.nih.gov
Phase 0/1 trial of ONC206 - a novel imipridone for children with diffuse midline gliomas and recurrent malignant brain tumorsNIHNational Cancer Institute2022 to 2025$1,826,791September 7, 2022August 31, 2028MUELLER, SABINEreporter.nih.gov
Investigating genetic ancestry influences on oral cavity and laryngeal cancer survival disparitiesNIHNational Cancer Institute2021 to 2023$1,823,126March 1, 2019February 28, 2025RAGIN, CAMILLE C.reporter.nih.gov
Universal Internal Standard for Reproducible Accurate Quantification of Exosome Protein MarkersNIHNational Cancer Institute2022 to 2025$1,817,095January 14, 2022December 31, 2026LUBMAN, DAVID M.reporter.nih.gov
Cellular plasticity in salivary gland regeneration.NIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,816,873March 1, 2021December 31, 2024OVITT, CATHERINEreporter.nih.gov
Use of radioprotector in rectal cancerNIHNational Cancer Institute2022 to 2025$1,812,623April 8, 2022January 31, 2028OBERLEY-DEEGAN, REBECCA Ereporter.nih.gov
THE OVERALL SCOPE OF THIS REQUIREMENT IS TO SUPPORT AND MAINTAIN THE CURRENT ELECTRONIC PATHOLOGY REPORTING INFRASTRUCTURE, INCLUDING MAINTAINING CONTNIHNational Cancer Institute2021 to 2022$1,808,329September 26, 2020September 25, 2023LLOYD, MARKreporter.nih.gov
Dual function theranostic constructs for photoacoustic guided surgery and photodynamic therapyNIHNational Cancer Institute2021 to 2025$1,801,875April 1, 2019June 30, 2026HASAN, TAYYABAreporter.nih.gov
10-year Comparative Effectiveness and Harms of Treatments for Prostate CancerNIHNational Cancer Institute2021 to 2023$1,788,766April 1, 2019December 31, 2024BAROCAS, DANIEL Areporter.nih.gov
VLA-4–targeted 67Cu-LLP2A preconditioning enhances efficacy of T-cell-based adoptive immunotherapyNIHNational Cancer Institute2023 to 2025$1,788,311July 5, 2023June 30, 2028PATEL, RAVI BHASKERreporter.nih.gov
Roles of resident macrophages in salivary gland development, homeostasis, regeneration, and function restoration after radiotherapyNIHNational Institute of Dental & Craniofacial Research2021 to 2025$1,788,269September 20, 2021June 30, 2027LIU, FEIreporter.nih.gov
Targeting Tryptophan Metabolism in Rectal CancerNIHNational Cancer Institute2023 to 2025$1,780,760September 21, 2023August 31, 2028CIORBA, MATTHEW AARONreporter.nih.gov
Combined magnetophoresis and photodynamic therapy for the treatment of TNBCNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$1,780,757June 15, 2021August 31, 2025TSOURKAS, ANDREWreporter.nih.gov
Advanced PET-CT Directed Post-Prostatectomy Radiotherapy to Enhance Prostate Cancer OutcomesNIHNational Cancer Institute2021 to 2023$1,778,839May 1, 2019April 30, 2025JANI, ASHESHreporter.nih.gov
SCH: Personalized Rescheduling of Adaptive Radiation Therapy for Head & Neck CancerNIHNational Cancer Institute2021 to 2024$1,778,544May 1, 2021April 30, 2026SCHAEFER, ANDREW Jreporter.nih.gov
Tumor targeted drug delivery nanoplatform to overcome therapy resistance glioblastomaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,774,749December 1, 2022November 30, 2027QUINONES-HINOJOSA, ALFREDOreporter.nih.gov
Real-time Volumetric Imaging for Motion Management and Dose Delivery VerificationNIHNational Cancer Institute2023 to 2025$1,771,308April 24, 2023March 31, 2028YANG, XIAOFENGreporter.nih.gov
Targeting the DNA damage response in combination with radiation to induce innate immunity and improve immunotherapy efficacy in pancreatic cancerNIHNational Cancer Institute2021 to 2024$1,769,224March 1, 2020February 28, 2026MORGAN, MEREDITH Areporter.nih.gov
A Phase II Clinical Trial in Newly Diagnosed Glioblastoma Patients Treated with WP1066 and RadiationNIHNational Cancer Institute2023 to 2025$1,768,137May 5, 2023April 30, 2028HEIMBERGER, AMY BETHreporter.nih.gov
OPTICAL CHERENKOV IMAGING DOSIMETRY IN HUMAN RADIOTHERAPYNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2024$1,766,935March 1, 2022January 31, 2026POGUE, BRIAN WILLIAMreporter.nih.gov
Local Tumoral Delivered Immune Checkpoint Blockades Immunotherapy and Radioembolization Combination TherapyNIHNational Cancer Institute2023 to 2025$1,763,601September 1, 2023August 31, 2028KIM, DONG-HYUNreporter.nih.gov
Radiation-induced senescence in the brain microenvironment: Implications for glioblastoma recurrence and therapyNIHNational Cancer Institute2021 to 2025$1,762,474April 16, 2021March 31, 2027BURMA, SANDEEPreporter.nih.gov
Development of an antibody-oligonucleotide conjugate for treatment of Head and Neck Squamous Cell CarcinomaNIHNational Cancer Institute2024 to 2025$1,760,586September 18, 2024August 31, 2026SALEH, ANTHONY Dreporter.nih.gov
Biomaterial Drones for Image-Guided Drug Delivery during radiotherapyNIHNational Cancer Institute2021 to 2023$1,760,092September 8, 2021January 31, 2025NGWA, WILFREDreporter.nih.gov
A cost-effective radiation treatment delivery system for the low- and middle-income countriesNIHNational Cancer Institute2021 to 2022$1,757,058May 1, 2017August 31, 2023FORD, ERIC Creporter.nih.gov
Yittrium-90 radiation lobectomy: Dose optimization and prediction of FLR hypertrophy to enable resection of HCCNIHNational Cancer Institute2022 to 2025$1,755,197August 1, 2019July 31, 2026LEWANDOWSKI, ROBERT Jreporter.nih.gov
Targeting non-canonical p16 signaling to improve radiation response and outcome in head and neck cancerNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,754,171June 15, 2023May 31, 2028SKINNER, HEATH DEVINreporter.nih.gov
Novel Mechanistic Approaches in Prevention, Treatment and Non-Invasive Assessment of Radiation Cystitis in MiceNIHNational Cancer Institute2021 to 2024$1,753,498June 1, 2021May 31, 2026KANAI, ANTHONY JOHNreporter.nih.gov
Reorienting the Glioblastoma Microenvironment to Respond to ImmunotherapyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,750,330February 1, 2019January 31, 2025BARCELLOS-HOFF, MARY HELENreporter.nih.gov
YTHDF2 and UVB damage response in skin cancerNIHNational Institute of Environmental Health Sciences2021 to 2023$1,740,162May 1, 2015April 30, 2024HE, YU-YINGreporter.nih.gov
Exploiting Integrin Signaling to Overcome Resistance to ImmunotherapyNIHNational Cancer Institute2021 to 2024$1,738,599December 1, 2019November 30, 2025DENARDO, DAVID Greporter.nih.gov
A dyadic exercise approach to prevent declines in physical and mental health in couples during radiation treatment for cancer: a hybrid type I efficacy-implementation trialNIHNational Cancer Institute2023 to 2025$1,737,544July 1, 2023June 30, 2028WINTERS-STONE, KERRI Mreporter.nih.gov
Opaganib as a Medical Countermeasure for Gastrointestinal Acute Radiation SyndromeNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,734,918August 1, 2023July 31, 2025SMITH, CHARLES Dreporter.nih.gov
Optimizing Carbon Ion Therapy for Pediatric CNS TumorsNIHNational Cancer Institute2023 to 2025$1,727,977September 18, 2023August 31, 2028ELEY, JOHN G.reporter.nih.gov
Evaluation of TRPM8-expressing neurons as novel regulators of acute radiotherapy-associated pain in patients with head and neck cancerNIHNational Cancer Institute2021 to 2025$1,727,521March 1, 2021February 28, 2026NOLAN, MICHAEL WARRENreporter.nih.gov
Ablating Liver Metastases with SBRT to Enhance Immune Checkpoint Blockade in MelanomaNIHNational Cancer Institute2023 to 2025$1,722,266May 5, 2023April 30, 2028LAWRENCE, THEODORE Sreporter.nih.gov
Discovery of Small Molecule Ligands for PHD1 Reader Domain of Histone Demethylase KDM5ANIHNational Cancer Institute2021 to 2023$1,722,094July 1, 2020June 30, 2024FUJIMORI, DANICA GALONICreporter.nih.gov
Chemo-radio immunotherapy for pediatric brain tumorsNIHNational Cancer Institute2021 to 2023$1,721,832September 1, 2019August 31, 2025MUNN, DAVID H.reporter.nih.gov
An artificial intelligence-driven distributed stereotactic radiosurgery strategy for multiple brain metastases managementNIHNational Cancer Institute2021 to 2024$1,718,332January 1, 2019December 31, 2025GU, XUEJUNreporter.nih.gov
Role of Protein Methylation in Cell Mitosis and GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,708,924April 15, 2020December 31, 2025CHENG, SHI-YUANreporter.nih.gov
Polyamine and Glutamate Driven Interactions in the Glioblastoma-Brain MicroenvironmentNIHNational Cancer Institute2021 to 2025$1,706,819August 7, 2015January 31, 2027WELFORD, SCOTT MICHAELreporter.nih.gov
MR Fingerprinting based Quantitative Imaging and Analysis Platform (MRF-QIA) for brain tumors.NIHNational Cancer Institute2023 to 2025$1,706,274January 1, 2023December 31, 2028GRISWOLD, MARKreporter.nih.gov
The Radium-223 Combination Therapy Space; Improving Response and Clarifying ToxicitiesNIHNational Cancer Institute2021 to 2024$1,701,190March 1, 2020February 28, 2026THOREK, DANIEL LYNDON JAFFEreporter.nih.gov
Engineered Ensemble Nanoimmunotherapies for CancerNIHNational Cancer Institute2021 to 2024$1,699,559February 1, 2023January 31, 2025FERNANDES, ROHANreporter.nih.gov
Immunomodulation of the Tumor Microenvironment with Molecular Targeted Radiotherapy to Facilitate an Adaptive Anti-Tumor Immune Response to Combined Modality ImmunotherapiesNIHNational Cancer Institute2021 to 2022$1,695,219September 18, 2018August 31, 2023MORRIS, ZACHARY SCOTTreporter.nih.gov
Development of an NTSR1-Targeted Radiotherapeutic for Colorectal CancerNIHNational Cancer Institute2021 to 2025$1,691,139April 1, 2021March 31, 2027GARRISON, JERED Creporter.nih.gov
Stimulating Neo-Antigen Specific T Cell Responses in Head and Neck CancersNIHNational Institute of Dental & Craniofacial Research2021 to 2022$1,687,410September 19, 2018August 31, 2024SCHOENBERGER, STEPHEN PHILIPreporter.nih.gov
Clinical Development of Rhenium Nanoliposomes (RNL186) for GlioblastomaNIHNational Cancer Institute2021 to 2023$1,687,302September 9, 2019August 31, 2025BRENNER, ANDREW JACOBreporter.nih.gov
Utilization of Immuno-PET to detect response and guide novel oHSV-based therapy for gliomaNIHNational Cancer Institute2023 to 2025$1,685,761April 1, 2023March 31, 2028SORACE, ANNA Creporter.nih.gov
A Novel Hsp90 Inhibitor as a Chemo and Radiosensitizer in Adults with GlioblastomaNIHNational Cancer Institute2022 to 2024$1,680,455January 1, 2019July 31, 2025PUDUVALLI, VINAY Kreporter.nih.gov
The TOPAS Tool for Particle Simulation, a Monte Carlo Simulation Tool for Physics, Biology and Clinical ResearchNIHNational Cancer Institute2021 to 2022$1,680,360June 4, 2018May 31, 2024FADDEGON, BRUCEreporter.nih.gov
Multidimensional analyses to improve PSMA-RPT efficacy in mCRPCNIHNational Cancer Institute2023 to 2025$1,679,715July 12, 2023March 31, 2028CZERNIN, JOHANNESreporter.nih.gov
Sharpening the edge in pencil-beam proton therapy: an aftermarket collimation system to better spare normal tissue during radiation treatmentNIHNational Cancer Institute2021 to 2024$1,673,205September 1, 2018August 31, 2025HYER, DANIEL ELLISreporter.nih.gov
Effects of FLASH Radiation on Cancer and the Immune ResponseNIHNational Cancer Institute2021 to 2024$1,668,951July 1, 2019June 30, 2024ENGLEMAN, EDGAR G.reporter.nih.gov
Singlet Oxygen-cleavable Prodrugs for Treating Non-Muscle Invasive Bladder CancersNIHNational Cancer Institute2022 to 2025$1,665,189July 13, 2022June 30, 2027YOU, YOUNGJAEreporter.nih.gov
The telomere biomarker as a tool to inform decision-making for aggressive salvage therapy in men with rising PSA post prostatectomyNIHNational Cancer Institute2023 to 2025$1,663,456August 22, 2023July 31, 2027MEEKER, ALAN KEITHreporter.nih.gov
Immunogenomic predictors of outcomes in patients with locally advanced cervical cancer treated with immunotherapy and chemoradiationNIHNational Cancer Institute2023 to 2025$1,661,015July 1, 2023June 30, 2026ZAMARIN, DMITRIYreporter.nih.gov
Molecular analysis and therapeutic targeting of PI3K signaling in thyroid cancerNIHNational Cancer Institute2021 to 2024$1,660,465February 1, 2009November 30, 2025DI CRISTOFANO, ANTONIOreporter.nih.gov
Targeting adrenergic stress pathways to Increase tumor sensitivity to radiation and promote development of an anti-tumor immune responseNIHNational Cancer Institute2021 to 2023$1,659,234February 8, 2019January 31, 2025REPASKY, ELIZABETH Areporter.nih.gov
Mechanistic insights on structure, topology and radiation effects on RNA nanomedicinesNIHNational Cancer Institute2023 to 2025$1,658,625January 10, 2023December 31, 2027SUN, CONROY GHIN CHEEreporter.nih.gov
Cloud/Subscription based, Customer-Responsive Dosimetry Tool for alpha-Particle EmittersNIHNational Cancer Institute2024 to 2025$1,648,103August 5, 2024July 31, 2026GHALY, MICHAELreporter.nih.gov
Enhanced radiotherapy for pediatric glioma via synthetic lethal vulnerabilitiesNIHNational Cancer Institute2024 to 2025$1,637,935July 1, 2024June 30, 2026CHOWDHURY, DIPANJANreporter.nih.gov
Intra-salivary gland autotransplantation of marrow mesenchymal stromal cells for treatment of radiation induced xerostomiaNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,636,981April 1, 2023May 31, 2026KIMPLE, RANDALL J.reporter.nih.gov
Tumor-barcoding coupled with high-throughput sequencing for quantitative radiogenomics of the abscopal response in NSCLCNIHNational Cancer Institute2023 to 2025$1,635,382January 1, 2023August 31, 2025TRAN, PHUOC T.reporter.nih.gov
Fatty Acid Metabolic Regulation of Anti-Tumor Immunity Against Irradiated GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,632,860June 1, 2023May 31, 2028VANPOUILLE-BOX, CLAIRE ISABELLEreporter.nih.gov
In situ PEDSy and light delivery platform for Intracavitory Photodynamic TherapyNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,632,324September 20, 2020June 30, 2025ZHU, TIMOTHY C.reporter.nih.gov
Immune modulation of radiation therapy with Flt3 ligandNIHNational Cancer Institute2021$1,631,702September 1, 2015August 31, 2022KELER, TIBORreporter.nih.gov
Development of a RUVBL1/2 Inhibitor as a Radiosensitizer and Immune Stimulator for NSCLCNIHNational Cancer Institute2023 to 2025$1,626,628June 1, 2023May 31, 2028KITTLER, RALFreporter.nih.gov
Imaging and circulating DNA markers to assess early response and predict treatment failure patterns in lung cancerNIHNational Cancer Institute2021 to 2023$1,623,911February 1, 2019December 31, 2024LI, RUIJIANGreporter.nih.gov
Novel Isotopic Spectroscopy Imaging Tools for Advancing Targeted Alpha Cancer TherapiesNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$1,623,380September 1, 2024August 31, 2026MOORE, JARED WILLIAMreporter.nih.gov
Ultrasound-guided Ultra-steerable Histotripsy Array System for Non-invasive treatment of Soft Tissue SarcomaNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,617,112May 1, 2023April 30, 2027XU, ZHENreporter.nih.gov
Improving quantitative accuracy and tissue visualization in CBCT guided radiation therapyNIHNational Cancer Institute2021 to 2025$1,614,595September 15, 2020May 31, 2026ALTUNBAS, CEMreporter.nih.gov
A high sensitivity gamma camera using a combination of Compton reconstruction and source proximity for in-vivo imaging of Ac-225NIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2023$1,613,535September 30, 2022June 30, 2024CARAVACA, JAVIERreporter.nih.gov
Repolarizing the Tumor and Metastatic Microenvironments to Treat Patients with Pancreatic CancerNIHNational Cancer Institute2021 to 2025$1,605,800August 2, 2021August 31, 2025GERBER, SCOTT ANDREWreporter.nih.gov
Development of Potent Estrogen Receptor Beta Agonists for Treating GlioblastomaNIHNational Cancer Institute2023 to 2025$1,581,237January 1, 2023December 31, 2027VADLAMUDI, RATNA Kreporter.nih.gov
Quantitative (Perfusion and Diffusion) MRI Biomarkers to Measure Glioma ResponseNIHNational Cancer Institute2021 to 2023$1,576,805February 28, 2014August 31, 2024SCHMAINDA, KATHLEEN MARIEreporter.nih.gov
In situ radioimmunotherapy to maximize the engagement of conventional type 1 dendritic cells against non-T cell-inflamed tumorsNIHNational Cancer Institute2022 to 2025$1,573,391August 1, 2021July 31, 2026ITO, FUMITOreporter.nih.gov
Spatially precise radio-chemo-immunotherapy using antibody conjugatesNIHNational Cancer Institute2023 to 2025$1,572,584December 1, 2022November 30, 2027ADVANI, SUNIL Jreporter.nih.gov
“Pharmacologic targeting of NR4A1 and NR4A2 to activate glioblastoma treatment response”NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,569,424September 19, 2023August 31, 2028ROSTOMILY, ROBERT Creporter.nih.gov
Novel Minimally Invasive Endobronchial Approach for Lung Cancer AblationNIHNational Cancer Institute2021 to 2022$1,567,912April 1, 2019August 31, 2025LEVIN, HOWARDreporter.nih.gov
Development of AI-Augmented quality assurance tools for radiation therapyNIHNational Cancer Institute2023 to 2025$1,565,343February 1, 2023January 31, 2028XING, LEIreporter.nih.gov
Developing BRAF mutant and BRAF wild-type selective strategies for radiosensitization in Anaplastic Thyroid CancerNIHNational Cancer Institute2021 to 2025$1,562,097August 1, 2020April 30, 2027WILLIAMS, TERENCE MARQUESreporter.nih.gov
Self-Assembling Camptothecin Nanofiber Hydrogels as Adjunct Therapy for Intraoperative Treatment of Malignant GliomaNIHNational Cancer Institute2023 to 2025$1,553,525September 4, 2023August 31, 2028CUI, HONGGANGreporter.nih.gov
The P2X7 receptor for ATP as a therapeutic target in the prevention of radiation-induced salivary gland dysfunctionNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,547,373April 1, 2023January 31, 2028WEISMAN, GARY ANDREWreporter.nih.gov
Whole-brain Spectroscopy Guided Personalized Mapping of Transducer Arrays for Glioblastoma Patients Receiving Tumor Treating FieldsNIHNational Cancer Institute2021 to 2025$1,547,216September 1, 2021May 31, 2027MOHAN, SUYASHreporter.nih.gov
Optimal Decision Making in Radiotherapy Using Panomics AnalyticsNIHNational Cancer Institute2021 to 2023$1,536,845June 6, 2019May 31, 2025EL NAQA, ISSAM M.reporter.nih.gov
Dissecting NF-kB pathway in HPV-associated head and neck cancerNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,535,027March 1, 2023December 31, 2027YARBROUGH, WENDELL Greporter.nih.gov
Alpha particles combined with ATR inhibition to activate the immune system: mechanisms and pre-clinical translationNIHNational Cancer Institute2023 to 2025$1,534,588June 12, 2023May 31, 2028SAWAKUCHI, GABRIEL OLIVEIRAreporter.nih.gov
A novel, transferable sialylation-mediated mechanism of chemoradioresistance in GI cancerNIHNational Cancer Institute2022 to 2025$1,527,409February 1, 2022January 31, 2027HARDIMAN, KARIN MARIEreporter.nih.gov
Novel focused ultrasound enhanced calreticulin-nanoparticle for immune primed melanoma immunotherapyNIHNational Cancer Institute2023 to 2025$1,525,979June 4, 2019July 31, 2027RANJAN, ASHISHreporter.nih.gov
Integrating multi-omics, imaging, and longitudinal data to predict radiation response in cervical cancerNIHNational Cancer Institute2023 to 2025$1,522,810September 7, 2023August 31, 2028ZHANG, JINreporter.nih.gov
The Role of Mono-ADP-Ribosylation by PARP14 in RadioresistanceNIHNational Institute of Environmental Health Sciences2022 to 2025$1,518,132February 1, 2016December 31, 2026MOLDOVAN, GEORGE LUCIANreporter.nih.gov
Ultra-high precision image-guided incisionless transcranial ultrasound surgeryNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$1,514,111August 20, 2024April 30, 2028PINTON, GIANMARCOreporter.nih.gov
Radioprotective effect of p53 against oral mucositisNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,510,501September 7, 2023June 30, 2028LEE, CHANG-LUNGreporter.nih.gov
Bioinspired chemical probe approach targeting telomerase reverse transcriptaseNIHNational Cancer Institute2021 to 2024$1,508,707September 1, 2020May 31, 2025SCHEIDT, KARL Areporter.nih.gov
Role of gasdermin D in bone resorptionNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$1,505,677February 15, 2020January 31, 2025MBALAVIELE, GABRIELreporter.nih.gov
Customized nanofibers with preferential lung-targeting properties for treating metastatic pulmonary tumorsNIHNational Cancer Institute2023 to 2025$1,505,461April 10, 2023July 31, 2027BELLAT, VANESSAreporter.nih.gov
Utilizing Radiation-Induced Multi-potency to Increase the Efficacy of RadiotherapyNIHNational Cancer Institute2023 to 2025$1,501,570July 1, 2023June 30, 2028PAJONK, FRANKreporter.nih.gov
Mitigation of Radiation Therapy Induced Neuroinflammation and Cognitive DysfunctionNIHNational Cancer Institute2021 to 2022$1,499,121May 1, 2019July 31, 2025SHIFRIN, VICTORreporter.nih.gov
Translating Intestinal Radioprotection by EGLN Inhibition to Improve Clinical Outcomes in Unresectable Pancreatic CancerNIHNational Cancer Institute2021 to 2023$1,496,161April 1, 2019March 31, 2024KOONG, ALBERTreporter.nih.gov
Randomized Prospective Phase II Clinical Trial of NVX-108 in Association with Chemoradiation of GlioblastomaNIHNational Cancer Institute2022 to 2023$1,492,571May 24, 2010February 29, 2024UNGER, EVAN CHARLESreporter.nih.gov
Targeting the immunosuppressive tumor microenvironment to enhance efficacy of radiotherapy and immuno-radiotherapy for oral cancerNIHNational Institute of Dental & Craniofacial Research2021 to 2022$1,491,576September 2, 2020August 31, 2024SIKORA, ANDREWreporter.nih.gov
Sonodynamic therapy using MRI-guided focused ultrasound in combination with 5-aminolevulinic acid to treat recurrent glioblastoma multiformeNIHNational Cancer Institute2023 to 2025$1,491,029April 1, 2023August 31, 2027MARCUS, STUARTreporter.nih.gov
Definition of Immune Infiltrate Phenotype and DNA Damage Response Deficits Across Diverse Murine Mammary CarcinomasNIHNational Cancer Institute2021 to 2023$1,489,798April 1, 2019March 31, 2024BARCELLOS-HOFF, MARY HELENreporter.nih.gov
Regulation of the Hedgehog pathway and Medulloblastoma response to radiochemotherapyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,482,576April 15, 2021February 28, 2027PEI, HUADONGreporter.nih.gov
HPV genomic structure in cervical cancer radiation response and recurrence detectionNIHNational Cancer Institute2023 to 2025$1,478,822May 1, 2023April 30, 2028ZHANG, JINreporter.nih.gov
Rewiring the myeloid cell response to adjuvants to improve tumor controlNIHNational Cancer Institute2021 to 2024$1,475,782December 2, 2019November 30, 2024GOUGH, MICHAEL JAMESreporter.nih.gov
Intrathecal delivery of radiation sensitizing nanoparticles in pediatric neuro-oncologyNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2023$1,473,715August 2, 2019June 30, 2025SIRIANNI, RACHAEL Wreporter.nih.gov
Genetic Modifiers of Radiation Therapy-Induced CardiotoxicityNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,471,801June 1, 2019May 31, 2025BERGOM, CARMENreporter.nih.gov
Advancing Systematic Delivery of Oncolytic Adenovirus for Pancreatic CancerNIHNational Cancer Institute2023 to 2025$1,471,216July 1, 2023June 30, 2028DAVYDOVA, JULIAreporter.nih.gov
Working towards targeted therapy in H3K27M tumors: Aurora Kinase Inhibitors and the role of epigenome programmingNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,467,722September 1, 2020May 31, 2025DANIELS, DAVIDreporter.nih.gov
Simultaneous dose and dose rate optimization for clinical FLASH proton radiotherapyNIHNational Cancer Institute2022 to 2025$1,464,835June 1, 2022July 31, 2025GAO, HAOreporter.nih.gov
Myeloid cells and radiation-induced memory deficits in rodent glioma model: sex and age effectsNIHNational Cancer Institute2021 to 2024$1,463,670July 1, 2020June 30, 2026GUPTA, NALINreporter.nih.gov
A Combination Therapy to Treat Cancer-Related FatigueNIHNational Cancer Institute2021 to 2023$1,457,679December 1, 2018November 30, 2024YENNU, SRIRAMreporter.nih.gov
Targeting Glioblastoma with a Nuclear-penetrating Anti-DNA AutoantibodyNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,454,633April 1, 2020January 31, 2026HANSEN, JAMES E.reporter.nih.gov
PET Biomarker for synaptic density changes after radiation therapyNIHNational Cancer Institute2024 to 2025$1,454,243September 3, 2024August 31, 2028ABOIAN, MARIAMreporter.nih.gov
The Role of ZEB1 in promoting therapeutic resistance through its interaction with 53BP1NIHNational Cancer Institute2022 to 2025$1,451,865February 1, 2022January 31, 2027LARNER, JAMES Mreporter.nih.gov
Intelligent treatment planning for cancer radiotherapyNIHNational Cancer Institute2021 to 2023$1,450,793April 1, 2019March 31, 2025JIANG, STEVE BINreporter.nih.gov
Interstitial Photodynamic Therapy Following Palliative Radiotherapy for Patients with Inoperable Malignant Central Airway ObstructionNIHNational Cancer Institute2024 to 2025$1,450,785March 1, 2024February 28, 2029SHAFIRSTEIN, GALreporter.nih.gov
Comparative modeling of sarcoma microenvironments for the discovery of biomarkers and tumor vulnerabilitiesNIHNational Cancer Institute2021 to 2024$1,445,109March 26, 2021August 30, 2024GUARNERIO, JLENIAreporter.nih.gov
Nano-therapeutics Reprogramming of Immunosuppressive Myeloid Cells Potentiate Radiotherapy for GlioblastomaNIHNational Cancer Institute2022 to 2025$1,438,381July 26, 2022June 30, 2027ZHANG, PENGreporter.nih.gov
A biomarker-driven strategy to guide the use of radiotherapy in non-small cell lung cancerNIHNational Cancer Institute2021 to 2024$1,437,238June 1, 2023May 31, 2025ABAZEED, MOHAMED E.reporter.nih.gov
X-ray/optical tomographic guidance and assessment for pre-clinical radiation ResearchNIHNational Cancer Institute2022 to 2025$1,436,489July 1, 2025August 31, 2026WANG, KEN KANG-HSINreporter.nih.gov
K12 Training for Clinical and Translational Oncology ResearchersNIHNational Cancer Institute2023 to 2025$1,429,078September 20, 2023August 31, 2028MEHNERT, JANICE M.reporter.nih.gov
The role of nuclear PD-L1 in breast tumor cell division, progression and therapy responseNIHNational Cancer Institute2021 to 2024$1,422,117March 1, 2020February 28, 2025WANG, LIEWEIreporter.nih.gov
Elucidation and therapeutic exploitation of PAK mediated radioresistanceNIHNational Cancer Institute2021 to 2024$1,419,736December 18, 2017November 30, 2025ADVANI, SUNIL Jreporter.nih.gov
Characterizing the theranostic potential of DLL3-targeting agents in high-grade neuroendocrine carcinomas of the lung and prostateNIHNational Cancer Institute2024 to 2025$1,419,480July 2, 2024June 30, 2028BODEI, LISAreporter.nih.gov
Translational Application of Magnetic Hyperthermia Therapy with Adjuvant Therapies for GlioblastomaNIHNational Cancer Institute2021 to 2022$1,419,392December 1, 2019September 30, 2022HADJIPANAYIS, CONSTANTINOS GEORGEreporter.nih.gov
Mechanisms of Arrhythmias Following Cardiac IrradiationNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,418,835April 1, 2020March 31, 2025LONDON, BARRYreporter.nih.gov
Rational translation of gold nanoparticle mediated radiosensitization to the clinicNIHNational Cancer Institute2023 to 2025$1,412,352January 13, 2021December 31, 2026KRISHNAN, SUNILreporter.nih.gov
Artificial Intelligence powered virtual digital twins to construct and validate AI automated tools for safer MR-guided adaptive RT of abdominal cancersNIHNational Institute of Biomedical Imaging and Bioengineering2023 to 2025$1,408,790September 1, 2023August 31, 2027TYAGI, NEELAMreporter.nih.gov
MR-Guided Precision Conformal Ablation Therapy for Brain TumorsNIHNational Cancer Institute2021 to 2022$1,400,508May 17, 2013August 31, 2025ZHANG, HAICHONGreporter.nih.gov
DNA damage signaling to dormant origins of replicationNIHNational Cancer Institute2021 to 2024$1,399,757December 1, 2019November 30, 2025BAKKENIST, CHRISTOPHER J.reporter.nih.gov
Artificial Intelligence Driven Automatic Treatment Planning of Stereotactic Radiosurgery for the Management of Multiple Brain MetastasesNIHNational Cancer Institute2022 to 2025$1,399,709September 1, 2022August 31, 2027TIAN, ZHENreporter.nih.gov
Targeting the BCL2 immune checkpoint to enhance the immunostimulatory effects of radiation in breast cancerNIHNational Cancer Institute2024 to 2025$1,394,261August 1, 2023July 31, 2028GALLUZZI, LORENZOreporter.nih.gov
ALK Rearrangements in Aggressive Thyroid CancerNIHNational Cancer Institute2021 to 2024$1,393,178July 1, 2014June 30, 2025NIKIFOROV, YURI Ereporter.nih.gov
Novel Optimization Methods and Treatment Planning System for Clinically-Deliverable Truly-Hybrid Proton-Photon RadiotherapyNIHNational Cancer Institute2021 to 2024$1,391,526April 1, 2021August 31, 2026GAO, HAOreporter.nih.gov
PAIRS: Validating telomerase reverse transcriptase (TERT) as an intrinsic vulnerability toward sensitizing cancer to radiationNIHNational Cancer Institute2023 to 2025$1,391,024July 1, 2023June 30, 2028KRON, STEPHEN J.reporter.nih.gov
Dual-Tracer PET Tumor ImagingNIHNational Cancer Institute2022 to 2023$1,389,678December 1, 2020August 31, 2025KADRMAS, DAN Jreporter.nih.gov
Development of A High Throughput Image-Guided IMRT System forPreclinical ResearchNIHNational Cancer Institute2023 to 2025$1,389,000June 18, 2021May 31, 2027SHENG, KEreporter.nih.gov
Modeling Susceptibility to Radiation Therapy-induced Cardiotoxicity Using Cell Village iPSCsNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,387,988December 1, 2023November 30, 2027WU, JOSEPH C.reporter.nih.gov
Treatment of Functional Deficits IN tongue muscles induced by radiation and chemoradiation treatmentNIHNational Cancer Institute2021 to 2024$1,386,490January 1, 2018December 31, 2025RUSSELL, JOHN Areporter.nih.gov
ATF3 Regulation of Histone Acetylation in Genome MaintenanceNIHNational Cancer Institute2021 to 2025$1,384,442April 10, 2020March 31, 2027YAN, CHUNHONGreporter.nih.gov
Long term radiation treatment planning in brain tumors in the pediatric populationNIHNational Cancer Institute2024 to 2025$1,384,140July 1, 2024June 30, 2027LOW, JUSTINreporter.nih.gov
NAD+ Pathway Signaling in Glioblastoma Tumor Growth and Therapy ResistanceNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,377,703July 1, 2019June 30, 2025KIM, ALBERT HONG-JAEreporter.nih.gov
White Matter Toxicity and Neurocognitive Outcomes in Pediatric Brain Tumor Patients Treated with Proton Beam Radiation TherapyNIHNational Cancer Institute2021 to 2023$1,376,955June 16, 2017November 30, 2024KAHALLEY, LISA SCHUMreporter.nih.gov
Developing a bank of purified myeloid progenitor cells as a bridging therapy for transient pancytopenia resulting from radiation injuryNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,375,113August 14, 2024July 31, 2027JOHNSTONE, BRIAN H.reporter.nih.gov
Toward precision radiotherapy: Physiological modeling of respiratory motion based on ultra-quality 4D-MRINIHNational Cancer Institute2021 to 2023$1,374,850July 18, 2019June 30, 2025MILLER, G. WILSONreporter.nih.gov
Genomics-based Mechanistic Investigation of Cancer-treatment Related Cardiotoxicity among Survivors of Childhood CancerNIHNational Cancer Institute2024 to 2025$1,373,343May 3, 2024April 30, 2026SAPKOTA, YADAVreporter.nih.gov
Translational Application of Magnetic Hyperthermia Therapy with Adjuvant Therapies for GlioblastomaNIHNational Cancer Institute2023 to 2024$1,372,507December 1, 2019November 30, 2025HADJIPANAYIS, CONSTANTINOS GEORGEreporter.nih.gov
Targeting the HIF-2 Signaling Pathway as a Radioprotective Strategy for BoneNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$1,370,754July 15, 2022June 30, 2027WU, COLLEENreporter.nih.gov
Development and application of non-thermal high frequency IRE to treat hepatic tumorsNIHNational Cancer Institute2021 to 2023$1,358,929April 1, 2020August 9, 2023DAVALOS, RAFAEL VIDALreporter.nih.gov
Novel PET Imaging to Guide Therapy in Hepatocellular CarcinomaNIHNational Cancer Institute2024 to 2025$1,357,029August 1, 2024July 31, 2029MANNING, HENRY CHARLESreporter.nih.gov
Novel extremophile-inspired radioprotectantsNIHNational Cancer Institute2024$1,354,009September 1, 2024August 31, 2027BYRNE, JAMES DONALDreporter.nih.gov
Quantitative Oncologic PET-MRNIHNational Cancer Institute2021 to 2023$1,353,874May 1, 2012April 30, 2024EL FAKHRI, GEORGESreporter.nih.gov
Quantitative MRI to automatically delineate intraprostatic tumor for radiation therapyNIHNational Cancer Institute2024 to 2025$1,353,393July 1, 2024June 30, 2029QING, KUNreporter.nih.gov
Regulation of Tumor Immunogenicity in GlioblastomaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,352,288April 1, 2023February 29, 2028HO, SZE CHUN WINSONreporter.nih.gov
CD 1530, an RAR Gamma Agonist for Oral Cavity Squamous Cell Carcinoma PreventionNIHNational Cancer Institute2023 to 2025$1,348,818September 11, 2023August 31, 2028GUDAS, LORRAINE Jreporter.nih.gov
Alpha-Emitter Therapy of OsteosarcomaNIHNational Cancer Institute2024 to 2025$1,347,161June 1, 2024May 31, 2026KRAITCHMAN, DARA Lreporter.nih.gov
Oral Cavity Quantitative Histomorphometric Risk Classifier (OHbIC) in Oral Cavity Squamous Cell Carcinoma (OC-SCC)NIHNational Cancer Institute2021 to 2022$1,343,970December 30, 2020July 14, 2022MADABHUSHI, ANANTreporter.nih.gov
ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancerNIHNational Cancer Institute2022 to 2025$1,339,222September 1, 2022August 31, 2027AGGARWAL, AJAYreporter.nih.gov
The role of amphiregulin in mediating radiation cystitis in cancer survivorsNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,337,343April 15, 2023February 29, 2028ZWAANS, BERNADETTE MARGARETHA MARIAreporter.nih.gov
Microbubble Cavitation for Improving Hepatocellular Carcinoma RadioembolizationNIHNational Cancer Institute2021 to 2024$1,332,481December 11, 2019November 30, 2025EISENBREY, JOHNreporter.nih.gov
Assessment of hyperthermia-based multimodal approach for hepatic colorectal metastasesNIHNational Cancer Institute2023 to 2025$1,326,934September 19, 2023July 31, 2028LEE, YONG JUNreporter.nih.gov
3-dimensional prompt gamma imaging for online proton beam dose verificationNIHNational Cancer Institute2023 to 2025$1,321,880May 15, 2023April 30, 2028REN, LEIreporter.nih.gov
Disparate Survival, Disparate Workforce: An Integrated Approach to Improving Head and Neck Cancer Outcomes and Diversity in the Oncology WorkforceNIHNational Institute of Dental & Craniofacial Research2024 to 2025$1,321,287April 15, 2024January 31, 2029WATTS, TAMMARA L.reporter.nih.gov
Photodynamic therapy with prior inhibition of epidermal growth factor receptor to stimulate antitumor innate immune responseNIHNational Cancer Institute2021 to 2023$1,315,419January 1, 2019December 31, 2024BUSCH, THERESA Mreporter.nih.gov
Combined Imaging and RNA Analyses to Develop Cervical Cancer BiomarkersNIHNational Cancer Institute2024 to 2025$1,309,803June 10, 2024May 31, 2029LI, HUAreporter.nih.gov
Determinants of transdermal drug delivery to the normal and the radiated breastNIHNational Cancer Institute2021 to 2023$1,309,585February 5, 2019January 31, 2026KHAN, SEEMA AHSANreporter.nih.gov
Targeting tumoral Lactobacillus iners to improve outcomes in cervical cancersNIHNational Cancer Institute2024 to 2025$1,309,419July 1, 2024June 30, 2029COLBERT, LAUREN ELIZABETHreporter.nih.gov
Epigenetically regulated stemness program and stem cell niche as targets in pediatric DIPGNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,308,288June 1, 2023April 30, 2028GALBAN, STEFANIEreporter.nih.gov
High-Throughput Screening and Validation of Molecular Targeted ChemoradiosensitizersNIHNational Cancer Institute2021 to 2022$1,308,250July 1, 2018June 30, 2024WILLERS, HENNINGreporter.nih.gov
Mitochondria electron transport chain complexes adaptative responses to cellular stressNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,304,730July 1, 2023June 30, 2028GRIGUER, CORINNE E.reporter.nih.gov
Dose-Response in Radionuclide TherapyNIHNational Cancer Institute2021 to 2022$1,302,997May 1, 2006June 30, 2023SGOUROS, GEORGEreporter.nih.gov
A novel molecularly targeted theranostic approach via the alphavbeta6 integrin for the detection and treatment of metastatic cancersNIHNational Cancer Institute2023 to 2024$1,299,432September 21, 2023August 31, 2028SUTCLIFFE, JULIE Lreporter.nih.gov
Mechanisms of radioresistance and strategies for radiosensitization in ovarian clear cell carcinomaNIHNational Cancer Institute2021 to 2025$1,295,411August 16, 2016July 31, 2027PENG, GUANGreporter.nih.gov
Stem cell-derived exosomes to ameliorate chemobrainNIHNational Cancer Institute2023 to 2025$1,294,957March 13, 2023February 29, 2028ACHARYA, MUNJAL Mreporter.nih.gov
Enhancing radioligand therapy for prostate cancer with biomarker and dosimetry guided personalizationNIHNational Cancer Institute2024 to 2025$1,289,060September 17, 2024August 31, 2029DEWARAJA, YUNI Kreporter.nih.gov
Maximizing tumor responses to targeted radiotherapy with a conditionally activated membrane binding probeNIHNational Cancer Institute2024 to 2025$1,285,968December 22, 2023November 30, 2028EVANS, MICHAEL JOHNreporter.nih.gov
Flexible Tools for Pre-Clinical Studies to Answer Key Questions UnderlyingHeavy-Ion RadiotherapyNIHNational Cancer Institute2021 to 2022$1,282,286April 5, 2019March 31, 2025BRENNER, DAVID JONATHANreporter.nih.gov
Alpha-Particle Emitter Peptide Receptor Targeted Radionuclide Therapy for Neuroendocrine TumorsNIHNational Cancer Institute2021 to 2024$1,276,665July 15, 2024May 31, 2026MENDA, YUSUFreporter.nih.gov
Development of a theragnostic radiopharmaceutical for pancreatic cancerNIHNational Cancer Institute2024 to 2025$1,275,825June 1, 2024May 31, 2029FERRARA, KATHERINE Wreporter.nih.gov
Therapeutic targeting mesenchymal transition in newly diagnosed and recurrent GBMNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,273,013September 15, 2024August 31, 2028FURNARI, FRANKreporter.nih.gov
Molecular Pathophysiology of Thyroid Cell GrowthNIHNational Cancer Institute2021 to 2023$1,271,119August 1, 1989November 30, 2024FAGIN, JAMES Areporter.nih.gov
Accelerated Brachytherapy Forward Chemoradiation Therapy (ABC-RT) for Cervical CancerNIHNational Cancer Institute2024 to 2025$1,270,410August 15, 2024July 31, 2029MARKOVINA, STEPHANIEreporter.nih.gov
Development and Evaluation of Advanced Non-Contrast Perfusion MRI for Monitoring Treatment Response in Brain MetastasesNIHNational Cancer Institute2023 to 2024$1,269,472September 1, 2023August 31, 2028QIN, QINreporter.nih.gov
Quantifying and Personalizing the Clinical Benefit of Metastasis-Directed Therapy in Men with De Novo Oligometastatic Prostate CancerNIHNational Cancer Institute2021 to 2025$1,267,741September 14, 2021August 31, 2028SPRATT, DANIEL EIDELBERGreporter.nih.gov
P-selectin-Mediated Targeting of PI3K Nanomedicines to the Tumor MicroenvironmentNIHNational Cancer Institute2021 to 2022$1,265,754December 15, 2017November 30, 2024HELLER, DANIEL ALANreporter.nih.gov
Role of DeltaNp63 alpha and TIP60 in SCC progression and chemoresistanceNIHNational Cancer Institute2024 to 2025$1,261,890December 7, 2023November 30, 2028KADAKIA, MADHAVI Preporter.nih.gov
Molecular and cellular mechanisms of neuronal damage caused by anticancer therapiesNIHNational Cancer Institute2024 to 2025$1,261,134March 1, 2024February 28, 2029DUMAN, JOSEPH Greporter.nih.gov
Transcranial Magnetic Resonance guided Histotripsy (tcMRgHt)NIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$1,259,901August 1, 2019April 30, 2024XU, ZHENreporter.nih.gov
Integration of CSF Proteogenomics in the Diagnosis and Management of Diffuse GliomasNIHNational Cancer Institute2024 to 2025$1,253,576July 3, 2024June 30, 2029MANSOURI, ALIREZAreporter.nih.gov
Lysosome Trapped FAP-Targeted Theranostics for Pancreatic CancerNIHNational Cancer Institute2024 to 2025$1,247,835March 18, 2024February 28, 2029GARRISON, JERED Creporter.nih.gov
Ionizing Radiation-Induced DNA damage repairNIHNational Cancer Institute2021 to 2023$1,245,640May 1, 2009August 31, 2025LIU, YILUNreporter.nih.gov
3D In vivo dosimetry for FLASH proton therapyNIHNational Cancer Institute2024 to 2025$1,243,736August 12, 2024July 31, 2029XIANG, SHAWN LIANGZHONGreporter.nih.gov
Combinations of Receptor-Targeted Alpha Radionuclide Therapy and Immune Checkpoint Inhibitors for Melanoma TreatmentNIHNational Cancer Institute2023 to 2025$1,240,605April 1, 2023April 2, 2025MIAO, YUBINreporter.nih.gov
Investigating the contribution of cellular senescence to the efficacy of radiation therapy.NIHNational Cancer Institute2021 to 2025$1,237,994September 1, 2021August 31, 2026ROMESSER, PAUL BERNARDreporter.nih.gov
COMBINATION HIGH-LET MOLECULAR RADIOTHERAPY OF RELAPSED REFRACTORY NEUROBLASTOMANIHNational Cancer Institute2024 to 2025$1,237,513September 17, 2024August 31, 2029ZHANG, HANWENreporter.nih.gov
Image-guided oxygen enhanced photodynamic therapy with multi-functional nanodroplets to improve head and neck cancer treatment outcomesNIHNational Cancer Institute2022 to 2025$1,234,632August 1, 2022July 31, 2028MALLIDI, SRIVALLEESHAreporter.nih.gov
Point-of-care optical spectroscopy platform and novel ratio-metric algorithms for rapid and systematic functional characterization of biological models in vivoNIHNational Institute of Dental & Craniofacial Research2023 to 2025$1,233,900August 1, 2023July 31, 2028ZHU, CAIGANGreporter.nih.gov
First-in-human clinical trial of proprietary oral gel to treat radiation-induced oral mucositis in cancer patientsNIHNational Cancer Institute2025$1,233,852September 15, 2025August 31, 2027YOUNG, CHRISTIANreporter.nih.gov
Development of an extracellular matrix-targeted theranostic radiopharmaceutical for metastatic lung cancerNIHNational Cancer Institute2025$1,233,778September 23, 2025August 31, 2027ZIMMERMANN, DENNISreporter.nih.gov
Enhanced Delivery of Cytotoxic Neural Stem Cells for Treatment of Glioblastoma Multiforme Using an Innovative In-situ Thermogelling Hydrogel and Focused UltrasoundNIHNational Cancer Institute2024 to 2025$1,233,216September 13, 2024August 31, 2029BENHABBOUR, SOUMYA RAHIMAreporter.nih.gov
Regulation of tumor recurrence by stress activated neutrophilsNIHNational Cancer Institute2022 to 2025$1,231,723June 1, 2020January 31, 2026ZHANG, RUGANGreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
University of TX MD Anderson Can CTRHouston, TX61$75.6 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY42$61.2 million0$0
University of California, San FranciscoSan Francisco, CA46$56.1 million0$0
NRG Oncology Foundation, Inc.Philadelphia, PA1$54.3 million0$0
Washington UniversitySaint Louis, MO38$52.5 million0$0
American College of RadiologyReston, VA1$48.9 million0$0
ST. Jude Children's Research HospitalMemphis, TN6$48.9 million0$0
Northwestern University at ChicagoChicago, IL13$47.4 million0$0
Johns Hopkins UniversityBaltimore, MD33$41.8 million0$0
University of Michigan at Ann ArborAnn Arbor, MI31$36.9 million0$0
Stanford UniversityStanford, CA35$36.3 million0$0
Massachusetts General HospitalBoston, MA30$35.8 million0$0
University of PennsylvaniaPhiladelphia, PA31$34 million0$0
Ut Southwestern Medical CenterDallas, TX26$30.4 million0$0
University of Wisconsin-MadisonMadison, WI28$28.1 million0$0
Duke UniversityDurham, NC30$26.9 million0$0
Beckman Research Institute/city of HopeDuarte, CA18$24.3 million0$0
Emory UniversityAtlanta, GA22$23 million0$0
Wake Forest University Health SciencesWinston-Salem, NC9$21.8 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA20$21.6 million0$0
University of California, San DiegoLa Jolla, CA20$20.7 million0$0
Case Western Reserve UniversityCleveland, OH17$19.9 million0$0
University of California-IrvineIrvine, CA8$19.3 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC19$18.6 million0$0
University of Colorado DenverAurora, CO17$18.6 million0$0
Ohio State UniversityColumbus, OH8$18.5 million0$0
University of ChicagoChicago, IL13$18.3 million0$0
University of California Los AngelesLos Angeles, CA20$18.1 million0$0
Fred Hutchinson Cancer CenterSeattle, WA14$17.1 million0$0
Vanderbilt University Medical CenterNashville, TN11$16.6 million0$0
University of RochesterRochester, NY14$16.5 million0$0
H. Lee Moffitt Cancer CTR & Res InstTampa, FL11$15.5 million0$0
Yale UniversityNew Haven, CT16$15.3 million0$0
University of IowaIowa City, IA15$15.2 million0$0
University of Texas HLTH Science CenterSan Antonio, TX9$15.1 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY11$14.9 million0$0
Weill Medical Coll of Cornell UnivNew York, NY17$14.8 million0$0
Dana-Farber Cancer InstBoston, MA11$14.7 million0$0
Mayo Clinic RochesterRochester, MN12$14.5 million0$0
Roswell Park Cancer Institute CorpBuffalo, NY10$13.8 million0$0
University of WashingtonSeattle, WA11$13 million0$0
University of Alabama at BirminghamBirmingham, AL13$12.7 million0$0
Thomas Jefferson UniversityPhiladelphia, PA13$12.4 million0$0
University of Maryland BaltimoreBaltimore, MD8$11.8 million0$0
Baylor College of MedicineHouston, TX6$10.7 million0$0
University of VirginiaCharlottesville, VA12$9.9 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH4$9.4 million0$0
University of California at DavisDavis, CA9$9.2 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA8$9.1 million0$0
Doseoptics, LLCLebanon, NH5$8.6 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX8$8.6 million0$0
University of Miami School of MedicineCoral Gables, FL7$8.2 million0$0
Columbia University Health SciencesNew York, NY8$8.1 million0$0
Augusta UniversityAugusta, GA7$8.1 million0$0
Medical College of WisconsinMilwaukee, WI5$8.1 million0$0
Medical University of South CarolinaCharleston, SC4$7.7 million0$0
Voximetry, Inc.Madison, WI3$7.5 million0$0
Georgia Tech Research CorporationAtlanta, GA5$7.4 million0$0
University of Nebraska Medical CenterOmaha, NE5$7.3 million0$0
Dartmouth CollegeHanover, NH7$7 million0$0
New York University School of MedicineNew York, NY6$6.7 million0$0
Viewpoint Molecular Targeting, Inc.Coralville, IA5$6.3 million0$0
Mayo Clinic JacksonvilleJacksonville, FL7$6.2 million0$0
University of KentuckyLexington, KY10$5.9 million0$0
University of Southern CaliforniaLos Angeles, CA5$5.9 million0$0
Chromologic, LLCMonrovia, CA3$5.8 million0$0
University of UtahSalt Lake City, UT10$5.3 million0$0
University of Missouri-ColumbiaColumbia, MO7$5.3 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA6$5.2 million0$0
Oregon Health & Science UniversityPortland, OR6$5.1 million0$0
Albert Einstein College of MedicineBronx, NY4$5 million0$0
Brigham and Women's HospitalBoston, MA4$4.8 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA3$4.7 million0$0
Collagen Medical, LLCBoston, MA2$4.3 million0$0
Allander Biotechnologies, Inc.Aurora, CO3$4.2 million0$0
Civatech Oncology, Inc.Morrisville, NC2$4.2 million0$0
Kaiser Foundation Research InstituteOakland, CA1$4 million0$0
Cellectar Biosciences, Inc.Florham Park, NJ2$4 million0$0
Celestial Oncology Inc.Santa Monica, CA1$3.9 million0$0
George Washington UniversityWashington, DC4$3.8 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA4$3.6 million0$0
University of Maryland, College ParkCollege Park, MD2$3.6 million0$0
Loma Linda UniversityLoma Linda, CA2$3.4 million0$0
Georgetown UniversityWashington, DC5$3.4 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ4$3.4 million0$0
Radiopharmaceutical Imaging and Dosimetry, LLCBaltimore, MD3$3.4 million0$0
University of Illinois at ChicagoChicago, IL2$3.3 million0$0
Beth Israel Deaconess Medical CenterBoston, MA2$3.3 million0$0
University of Kansas Medical CenterKansas City, KS3$3.2 million0$0
Texas A&m University Health Science CTRCollege Station, TX4$3.2 million0$0
Magee-Women's Res Inst and FoundationPittsburgh, PA1$3.2 million0$0
Providence Portland Medical CenterPortland, OR3$3.1 million0$0
Indiana University IndianapolisIndianapolis, IN2$3.1 million0$0
BCN Biosciences, LLCPasadena, CA1$3 million0$0
Biomimetix JV, LLCEnglewood, CO2$3 million0$0
University of CincinnatiCincinnati, OH3$3 million0$0
Carolinas Medical CenterCharlotte, NC2$3 million0$0
Fred Hutchinson Cancer Research CenterSeattle, WA8$2.9 million0$0
Myosin Therapeutics Inc.Jupiter, FL2$2.9 million0$0
Tibaray, Inc.Santa Clara, CA3$2.9 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025637$380,331,9980$0
2024676$357,197,6920$0
2023667$347,574,4310$0
2022674$344,001,5070$0
2021615$302,374,5600$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 17 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 5 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)PA-24-181NIHMay 8, 2027Not listedNotice number printed on 2 awards here
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)PA-24-185NIHMay 7, 2027Not listedNotice number printed on 1 award here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)PAR-27-089NIH93.395November 2, 2026Not listedSame assistance listing 93.395 as 540 awards here
Precision Approaches in Radiation Synthetic Combinations (PAIRS, RP1 Clinical Trial Optional)PAR-26-152NIH93.395November 11, 2026Not listedSame assistance listing 93.395 as 540 awards here
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)PAR-27-088NIH93.395November 20, 2026Not listedSame assistance listing 93.395 as 540 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.395January 7, 2027$375,000Same assistance listing 93.395 as 540 awards here
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)PAR-25-079NIH93.395January 7, 2027$500,000Same assistance listing 93.395 as 540 awards here
National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)PAR-25-081NIH93.395January 7, 2027$499,999Same assistance listing 93.395 as 540 awards here
Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)RFA-CA-27-005NIH93.395January 11, 2027$700,000Same assistance listing 93.395 as 540 awards here
Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)PAR-27-009NIH93.395January 25, 2027Not listedSame assistance listing 93.395 as 540 awards here
Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)RFA-CA-26-010NIH93.395January 25, 2027Not listedSame assistance listing 93.395 as 540 awards here
Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)RFA-CA-27-003NIH93.395January 25, 2027Not listedSame assistance listing 93.395 as 540 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.395April 5, 2027Not listedSame assistance listing 93.395 as 540 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.395April 5, 2027Not listedSame assistance listing 93.395 as 540 awards here
Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)RFA-CA-28-003NIH93.395June 11, 2027$600,000Same assistance listing 93.395 as 540 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIH93.395July 17, 2027Not listedSame assistance listing 93.395 as 540 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIH93.395September 7, 2027Not listedSame assistance listing 93.395 as 540 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.