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Data / Research funding / Pneumonia and Influenza

Pneumonia and Influenza: 754 NIH awards ($2B) to 212 organizations

754 NIH awards ($2B) in the NIH spending category Pneumonia and Influenza, to 212 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

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Awards

The 500 largest of 754 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
Statistical and Data Coordinating Center (SDCC) for Clinical Research in Infectious Diseases: Mpox Clinical Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$150,331,625March 1, 2021February 28, 2026EWELL, MARIANreporter.nih.gov
NIAID CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND RESPONSE: AVIAN INFLUENZA RESEARCHNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$91,354,067April 1, 2021January 14, 2027WEBBY, RICHARDreporter.nih.gov
COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTER: UNIVERSAL INFLUENZA VACCINE RESEARCHNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$72,825,966September 10, 2019September 24, 2026KRAMMER, FLORIANreporter.nih.gov
NIAID Centers of Excellence for Influenza Research and ResponseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$62,580,113April 1, 2021September 17, 2026GARCIA-SASTRE, ADOLFOreporter.nih.gov
CIVIC: University of Georgia Center for Influenza Vaccine Research in High Risk PopulationsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$53,879,677September 10, 2019September 9, 2026ROSS, TEDreporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers (CIVICs)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$52,452,735September 10, 2019September 9, 2026MOODY, TONYreporter.nih.gov
CEIRR: CORONAVIRUS RESEARCH ACTIVITIESNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$50,650,417April 1, 2021September 29, 2026HENSLEY, SCOTTreporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers (CIVICs): Component B: Vaccine Manufacturing and Toxicology CoreNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$44,296,051August 26, 2019March 13, 2028DENNY, THOMASreporter.nih.gov
Vanderbilt Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$36,564,580December 11, 2019November 30, 2026CREECH, CLARENCE BUDDYreporter.nih.gov
DIVINCI: Dissection of Influenza Vaccination and Infection for Childhood ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$30,010,720May 2, 2019April 30, 2027WEBBY, RICHARD JOHNreporter.nih.gov
NIAID Centers of Excellence for Influenza Research and Response (CEIRR): Avian Influenza Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$27,250,171April 1, 2021January 14, 2027LOWEN, ANICEreporter.nih.gov
Impact of the Initial Influenza Exposure on the Quality, Magnitude, Breadth, Potency and Durability of Influenza ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$24,789,202May 15, 2019April 30, 2027STAAT, MARY Areporter.nih.gov
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$23,280,590August 1, 2021January 14, 2027PEKOSZ, ANDREWreporter.nih.gov
Vaccine and Treatment Evaluation UnitsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$22,981,366December 11, 2019November 30, 2026ROUPHAEL, NADINE GEORGESreporter.nih.gov
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,625,203April 1, 2021September 14, 2027TOMPKINS, S. MARKreporter.nih.gov
Vaccine and Treatment Evaluation Unit at Saint Louis UniversityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$21,219,564December 11, 2019November 30, 2026HOFT, DANIEL F.reporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers (CIVICs): Component C: Clinical CoreNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$19,720,676September 16, 2019September 15, 2026FRANKENFIELD, JILLreporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers (CIVICs): Component C: Clinical CoreNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$16,914,921September 16, 2019September 30, 2026BERES, WENDELLreporter.nih.gov
Coordination for ARDS, Pneumonia, and Sepsis supporting Training, Organization and Network Efficiency (CAPSTONE)NIHNational Heart, Lung, and Blood Institute2023 to 2025$16,153,090May 1, 2023April 30, 2029SELF, WESLEY Hreporter.nih.gov
NIAID Influenza Data Processing and Communication Center: Universal Influenza Vaccine Research ActivitiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,386,477April 1, 2021March 31, 2026BOUR, STEPHANreporter.nih.gov
University of Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$15,173,751December 11, 2019November 30, 2026WALD, ANNAreporter.nih.gov
Kaiser Washington Vaccine and Treatment Evaluation UnitNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$14,173,633December 11, 2019November 30, 2026JACKSON, LISA Areporter.nih.gov
Establishment of the New York University Vaccine and Treatment Evaluation Unit (NYU VTEU)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$13,340,237April 10, 2020November 30, 2026MULLIGAN, MARK JOSEPHreporter.nih.gov
Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,580,221June 1, 2025May 31, 2027SETTE, ALESSANDROreporter.nih.gov
Cincinnati Children's Hospital Medical Center Vaccine and Treatment Evaluation Units (UM1 Clinical Trial Required)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$12,115,898December 11, 2019November 30, 2026FRENCK, ROBERT WILSONreporter.nih.gov
Development of an Optimized Adjuvanted TB VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$11,645,061September 30, 2021September 30, 2025EVANS, JAYreporter.nih.gov
Advanced Development of a Universal Influenza VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$10,853,574September 9, 2019April 24, 2025LOCHER, CHRISTOPHERreporter.nih.gov
ADJUVANT COMPARISON AND CHARACTERIZATIONNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$10,234,165September 1, 2022January 1, 2027FELGNER, PHILIPreporter.nih.gov
Viral Immunity and VAccination (VIVA) Human Immunology Project Consortium (HIPC)NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$9,862,919March 22, 2022February 28, 2027FERNANDEZ-SESMA, ANAreporter.nih.gov
Center for Modeling Complex InteractonsNIHNational Institute of General Medical Sciences2021 to 2024$9,684,540March 15, 2015June 30, 2025WICHMAN, HOLLY Areporter.nih.gov
A deep longitudinal analysis of next generation influenza vaccines in older adultsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$8,127,184January 1, 2022December 31, 2026UCAR, DUYGUreporter.nih.gov
Collaborative Influenza Vaccine Innovation Centers STATISTICAL, DATA MANAGEMENT AND COORDINATION CENTER (SDMCC)NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$7,400,390September 30, 2025September 29, 2026BOUR, STEPHANreporter.nih.gov
DEVELOPMENT OF VACCINES FOR INFLUENZA USING AN IMMUNO-MODULATOR ADJUVANT AND MULTI-PLATFORM APPROACHNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$7,281,050September 30, 2023September 29, 2028EL-KAMMASH, BRUXANNEreporter.nih.gov
Adjuvant Development of the TLR4 Ligand BECC470s For Use in Influenza, S. aureus, and P. aeruginosa VaccinesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$7,143,498September 30, 2023September 29, 2028SORENSON, GREGORYreporter.nih.gov
Emerging Infectious Diseases Research Center - East and Central AfricaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$6,734,930June 1, 2020June 5, 2025NJENGA, M KARIUKIreporter.nih.gov
Leveraging an ongoing longitudinal study of influenza vaccination to define immune signatures of response and risk of infection in older adults >75NIHNational Institute of Allergy and Infectious Diseases2022 to 2025$6,605,926December 9, 2021November 30, 2026LENG, SEAN XIAOreporter.nih.gov
DEVELOPMENT OF SMALL-MOLECULE DUAL ADJUVANT SYSTEM FOR INFLUENZA VIRUS VACCINENIHNational Institute of Allergy and Infectious Diseases2023 to 2025$6,359,752September 30, 2023September 29, 2028LAPEK, JENNIFERreporter.nih.gov
Developing Teixobactin for Respiratory InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$6,154,703March 22, 2021February 28, 2027HUGHES, DALLASreporter.nih.gov
DEVELOPMENT OF SAS A SYNTHETIC AS01-LIKE ADJUVANT SYSTEM FOR INFLUENZA VACCINESNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$5,907,864September 30, 2023September 29, 2028BURKHART, DAVIDreporter.nih.gov
Discovery of adjuvants via novel modulation of innate immune pathways for vaccines against influenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,841,904September 30, 2019April 30, 2026ESSER-KAHN, AARONreporter.nih.gov
Drivers of individual variation in influenza vaccine response and protection from infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$5,827,282July 14, 2022June 30, 2027COBEY, SARAHreporter.nih.gov
Task V02: Manufacture of Influenza for Human Challenge Clinical TrialsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$5,587,695May 15, 2018May 31, 2026HASSEL, THOMASreporter.nih.gov
Advanced Development of Vaccines for InfluenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,495,941September 9, 2019May 31, 2027STAERZ, UWEreporter.nih.gov
Development of vaccination strategies to elicit broadly protective immunity against influenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$5,165,779June 18, 2019June 30, 2029RAVETCH, JEFFREY VICTORreporter.nih.gov
Comparison of High vs. Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$5,116,475June 9, 2023March 31, 2028HALASA, NATASHA BASSAMreporter.nih.gov
The "Dynamics of the immune responses to repeat influenza vaccination exposures" (DRIVE) StudyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,955,723September 11, 2020June 30, 2026COBEY, SARAHreporter.nih.gov
Structure based design of trimer interface epitope focused universal influenza vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,864,362March 12, 2020February 28, 2025CROWE, JAMES Ereporter.nih.gov
Identification of Metabolic and Immune Deficits in the Aged Population and Their Restoration to Achieve Youthful Anti-Influenza Vaccine ResponsivenessNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$4,757,817November 22, 2021October 31, 2026MARASCO, WAYNE A.reporter.nih.gov
DYNAMICS AND EVOLUTION OF IMMUNE RESPONSES TO INFLUENZA VIRUSESNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$4,647,135June 29, 2020May 31, 2026ANTIA, RUSTOM NOSHIRreporter.nih.gov
Tissue factor-dependent coagulation in thrombosis and immune responsesNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,577,076February 1, 2021January 31, 2028MACKMAN, NIGELreporter.nih.gov
Molecular Analysis and Lineage Tracing of Influenza-Specific, Lung-Resident Memory B CellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,398,832April 7, 2020March 31, 2027RANDALL, TROY Dreporter.nih.gov
Inducible epithelial resistance: a program investigating mechanisms to protect against acute and chronic complications of pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2025$4,382,400March 5, 2019February 28, 2026EVANS, SCOTT E.reporter.nih.gov
VACCINES ADJUVANT DEVELOPMENT PROGRAM IN INFECTIOUS AND IMMUNE MEDIATED DISEASESNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$4,300,145September 30, 2023September 29, 2026DOWLING, DAVID JAMESreporter.nih.gov
Preclinical Pulmonary Fibrosis, an opportune rare disease cohortNIHNational Heart, Lung, and Blood Institute2022 to 2025$4,290,758August 20, 2020July 31, 2026SCHWARTZ, DAVID ALBERTreporter.nih.gov
Influenza pathogenesis in pregnancyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,248,239June 14, 2021May 31, 2027ADAMS WALDORF, KRISTINA M.reporter.nih.gov
Mechanism, Function, and Exploitation of Influenza A Virus-Activated Cell DeathNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$4,220,934September 25, 2017August 31, 2027BALACHANDRAN, SIDDHARTHreporter.nih.gov
Selecting HA glycosylation for improved vaccine responsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,957,417June 9, 2021May 31, 2027ZAIA, JOSEPHreporter.nih.gov
Microneedle Delivery of Zanamivir for the Treatment of Influenza InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,950,305March 1, 2017July 31, 2025LIPKA, ELKEreporter.nih.gov
Novel Immunogens to Elicit Broadly Cross-reactive Antibodies That Target the Hemagglutinin Head Trimer InterfaceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,892,523August 20, 2021July 31, 2025AZOITEI, MIHAI LUCHIANreporter.nih.gov
Derivation and Validation of the Pediatric Community-Acquired Pneumonia Severity (PedCAPS) ScoreNIHNational Heart, Lung, and Blood Institute2023 to 2025$3,862,565February 1, 2023January 31, 2028FLORIN, TODD ADAMreporter.nih.gov
Cellular and molecular programming of lung resident T cell memoryNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,857,630May 1, 2020April 30, 2027KOHLMEIER, JACOB Ereporter.nih.gov
Immune Dysfunction in HIV+ Opioid UsersNIHNational Institute on Drug Abuse2021 to 2025$3,823,539April 15, 2020January 31, 2027PAHWA, SAVITAreporter.nih.gov
Genetic Investigation of Covid 19 in Lung DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,774,284August 1, 2022July 31, 2027KAHN, MARK Lreporter.nih.gov
Restoring age-dependent vaccine unresponsiveness by a novel ASP-1 adjuvant combinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,749,095August 1, 2021May 31, 2027LUSTIGMAN, SARAreporter.nih.gov
Heterosubtypic immunity to influenza virus mediated by MHC-E-restricted memory NK cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,727,019September 24, 2021August 31, 2027JOST, STEPHANIEreporter.nih.gov
Discovery of Adjuvants that Direct T-cell Fates for Improved Safety and Efficacy in Vaccines Against Influenza and TuberculosisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$3,714,524September 30, 2025September 29, 2026ESSER-KAHN, AARONreporter.nih.gov
Inborn errors of immunity in patients with life-threatening COVID-19NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,707,765July 12, 2021June 30, 2026CASANOVA, JEAN-LAURENTreporter.nih.gov
THE ROLE OF THE NON-CANONICAL INFLAMMASOME IN INNATE IMMUNITYNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,707,189June 11, 2021May 31, 2027AMER, AMAL Oreporter.nih.gov
Flipped Germinal CentersNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,701,340September 17, 2021August 31, 2026WESEMANN, DUANE R.reporter.nih.gov
Programming of PMN host-defense function during transendothelial migrationNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,648,697June 11, 1993June 30, 2027KOMAROVA, YULIA Areporter.nih.gov
CD4_T-cell_Immunity_in_the_LungNIHNational Heart, Lung, and Blood Institute2021 to 2024$3,557,478February 1, 2018January 31, 2025KOLLS, JAY Kreporter.nih.gov
Novel mechanisms regulating immunity to respiratory virus infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,546,288August 2, 2023July 31, 2027PAUST, SILKEreporter.nih.gov
Combination nanovaccine-based immunization against influenza virus in the aged: immunity and protectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,518,508February 16, 2021January 31, 2027KOHUT, MARIAN Lreporter.nih.gov
Protective immunity elicited by distinct polysaccharide antigens of classical and hypervirulent KlebsiellaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,483,730September 1, 2023August 31, 2028ROSEN, DAVID A.reporter.nih.gov
Combination Adjuvants to Program Durable Immunity to Respiratory Viral and Fungal PathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,479,164February 17, 2016April 30, 2027SURESH, MARULASIDDAPPAreporter.nih.gov
Mechanistic Studies of Combination Adjuvants to Target B Cells in VaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,438,006April 23, 2021March 31, 2027TEYTON, LUCreporter.nih.gov
Deciphering the relationship between structure, dynamics and function in helical bundle proteinsNIHNational Institute of General Medical Sciences2021 to 2025$3,428,074May 1, 2017July 31, 2027DEGRADO, WILLIAMreporter.nih.gov
Immunobiology of Influenza Virus-related Critical Illness in Young HostsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,406,427September 18, 2020August 31, 2025RANDOLPH, ADRIENNE Greporter.nih.gov
Development of Gene-Silencing Therapeutics for Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,379,247August 1, 2019July 31, 2025GREENBERG, DAVID ELIHUreporter.nih.gov
Comparison of High Dose vs. Standard Dose Influenza Vaccines in Lung Allograft RecipientsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,375,497February 18, 2022January 31, 2027HALASA, NATASHA BASSAMreporter.nih.gov
Inhalation Therapy Platform for Coronavirus Infection TreatmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,373,230September 17, 2021August 31, 2026STAYTON, PATRICK S.reporter.nih.gov
Developing Inhibitors of Seasonal and Pandemic Influenza VirusesNIHNational Institute of Allergy and Infectious Diseases2025$3,352,410August 18, 2025July 31, 2029PLEMPER, RICHARD K.reporter.nih.gov
A Phase III Randomized Controlled Trial of Azithromycin for RSV-induced Respiratory Failure in ChildrenNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,324,945August 1, 2021July 31, 2027KONG, MICHELEreporter.nih.gov
The role of Chlamydia pneumoniae infection in Alzheimer's DiseaseNIHNational Institute on Aging2021 to 2025$3,300,943September 30, 2021June 30, 2027CROTHER, TIMOTHY ROBERTreporter.nih.gov
Development of 4-(aroylamino)piperidine-based entry inhibitors as anti-influenza therapeuticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,297,972April 2, 2021April 30, 2026RONG, LIJUNreporter.nih.gov
Comparison of High vs. Standard Dose Influenza Vaccines in Adult Solid Organ Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,293,620September 1, 2020June 30, 2025HALASA, NATASHA BASSAMreporter.nih.gov
Hybrid Methods for Dynamic Structure Analysis of Proteins from Pathogenic MicroorganismsNIHNational Institute of General Medical Sciences2021 to 2025$3,290,000July 1, 2021April 30, 2027MONTELIONE, GAETANO Treporter.nih.gov
Programming Durable Immune Responses To VaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,255,877December 18, 2018December 31, 2028ELLEBEDY, ALI HASSANreporter.nih.gov
Pulmonary pathophysiology sub-phenotypes of pneumoniaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,223,607February 1, 2022January 31, 2027MIZGERD, JOSEPH Preporter.nih.gov
Developing a bioprinted ventilated lung alveolar platform for investigating microbial interactions and influenza responseNIHNational Institute of Allergy and Infectious Diseases2025$3,182,827August 19, 2025July 31, 2029OH, JULIAreporter.nih.gov
Targeted Gene Delivery Systems Treating Lung DiseasesNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,172,072June 15, 2022May 31, 2026TIRRELL, MATTHEWreporter.nih.gov
Development and optimization of a peptide inhibitor of influenza virus splicing for broad-spectrum antiviral therapyNIHNational Institute of Allergy and Infectious Diseases2025$3,170,096August 1, 2025July 31, 2029TENOEVER, BENJAMIN R.reporter.nih.gov
Development of peptide nucleic acid antibioticsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,164,488February 10, 2021January 31, 2025ARYA, DEV PRIYAreporter.nih.gov
Structural interrogation of vaccine- and infection-induced B cell responsesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,116,277February 22, 2022January 31, 2027BAJIC, GORANreporter.nih.gov
Cardiovascular Risk, Vascular and Kidney Damage in COVID-19 SurvivorsNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,114,564January 20, 2022December 31, 2026CHIRINOS MEDINA, JULIO ALONSOreporter.nih.gov
Uncovering latent factors underlying weak and robust responses to influenza vaccine in healthy and obese older adultsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$3,095,170July 13, 2022June 30, 2027ALCORN, JOHN Freporter.nih.gov
The role of cryptic influenza virus proteins in replication and pathogenesisNIHNational Institute of Allergy and Infectious Diseases2025$3,085,097July 9, 2025June 30, 2029MEHLE, ANDREWreporter.nih.gov
Immunological characterization of rationally-designed vaccines against plague in mice and non-human primate modelsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,082,735February 1, 2021July 31, 2026CHOPRA, ASHOK Kreporter.nih.gov
Novel Strategies for Antibiotic Combinations to Combat Gram-negative SuperbugsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,081,358December 20, 2019November 30, 2025TSUJI, BRIANreporter.nih.gov
TCR-dependent and epigenetic mechanisms guiding influenza-specific CD4+ T cell responses in the lungNIHNational Institute of Allergy and Infectious Diseases2025$3,078,308August 1, 2025July 31, 2029HALE, JEFFREY SCOTTreporter.nih.gov
Genetic Analysis of COVID-19 Susceptibility and Resistance Determinants in the Collaborative CrossNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$3,064,576September 25, 2020August 31, 2025HEISE, MARK Treporter.nih.gov
Leveraging population-based human data to uncover mechanisms connecting Alzheimer's disease and common infections and facilitate vaccines repurposing for AD preventionNIHNational Institute on Aging2021 to 2025$3,052,023September 30, 2021June 30, 2027OUKRAINTSEVA, SVETLANA V.reporter.nih.gov
CoPARC: Colorado Pulmonary-Alcohol Research CollaborativeNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2025$3,045,581August 1, 2011April 30, 2029BURNHAM, ELLEN Lreporter.nih.gov
Biomimetic Macrophage Membrane-Coated Nanosponges: A Novel Therapeutic for Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Hospital-Associated PneumoniaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$3,027,494July 1, 2023June 30, 2028NIZET, VICTORreporter.nih.gov
Clonal Dynamics of the antibody responseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,017,736January 1, 2017December 31, 2026VICTORA, GABRIEL Dreporter.nih.gov
Evaluating darobactins as antimicrobial agentsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,000,880April 1, 2021March 31, 2026LEWIS, KIMreporter.nih.gov
Optimization of orally bioavailable inhibitors for the treatment of COVID-19 and other human coronavirus infectionsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,999,998June 7, 2023May 31, 2027COBURN, GLENreporter.nih.gov
Development of a Dual-Targeting ClpP Activating AntibioticNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,999,619September 1, 2023August 31, 2026LAFLEUR, MICHAELreporter.nih.gov
Aminoglycosides with reduced ototoxicityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,999,400August 1, 2020February 28, 2026ARYA, DEV PRIYAreporter.nih.gov
Universal Influenza A/B VaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,998,889August 7, 2020April 30, 2026BAGLEY, KENNETH Creporter.nih.gov
Vaccine Induced Immune-Inflammatory Response and Cardiovascular RiskNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,998,175April 1, 2021March 31, 2026CHENG, SUSANreporter.nih.gov
Innovations in Functional B Cell Epitope Discovery for InfluenzaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,991,588September 30, 2025September 29, 2026KELSOE, GARNETTreporter.nih.gov
Prevention and Treatment of Pneumocystis PneumoniaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,969,486May 21, 2020April 30, 2026NORRIS, KAREN Areporter.nih.gov
Novel G protein-based RSV vaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,967,937August 1, 2020March 31, 2027LI, SHENGQIANGreporter.nih.gov
Clinic-Ready MACH-1 Gene Gun for delivery of a universal influenza DNA vaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,964,030September 1, 2023August 31, 2026FRIZZELL, HANNAHreporter.nih.gov
Development of a broad spectrum teixobactin-lipopeptide hybrid for the treatment of lung infections caused by pan-drug resistant ‘superbugs’NIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,944,400June 21, 2022May 31, 2027RAO, GAURI Greporter.nih.gov
Kinase Regulation of Nuclear Speckle Function and Splicing during Influenza Virus InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,940,532May 25, 2016August 31, 2026LYNCH, KRISTEN Wreporter.nih.gov
Targeting abnormal alveolar immune activation and failed epithelial repair in COVID-19NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,933,325April 1, 2022March 31, 2026MISHARIN, ALEXANDERreporter.nih.gov
REDES: a peer network and mobile health (mHealth) enhanced CHW model to maximize COVID-19 vaccination among low income LatinosNIHNational Institute on Minority Health and Health Disparities2022 to 2025$2,925,112April 13, 2022October 31, 2027PAGE, KATHLEEN Rreporter.nih.gov
Mechanistic evaluation of the role of circadian rhythms in acute lung injury and subsequent recoveryNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,922,801September 20, 2021August 31, 2027SENGUPTA, SHAONreporter.nih.gov
Accelerating viral outbreak detection in US cities using mechanistic models, machine learning and diverse geospatial dataNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,917,739February 24, 2020January 31, 2025GALVANI, ALISON Preporter.nih.gov
Rapid response to pandemic influenza via multi-antigen RNA-based vaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,898,030February 10, 2022August 31, 2026CHAHAL, JASDAVEreporter.nih.gov
Impact of repeated vaccination on the effectiveness of seasonal influenza vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,895,020March 3, 2020February 28, 2027WAN, XIUFENG HENRYreporter.nih.gov
Evolution and Transmission of Influenza Virus in Natural Human InfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,893,554July 2, 2020June 30, 2026LAURING, ADAMreporter.nih.gov
Dual drug delivery to lung/blood interface in respiratory infections.NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,888,500April 20, 2021March 31, 2025MUZYKANTOV, VLADIMIR Rreporter.nih.gov
Development of an RSV vaccine for the elderlyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,887,888March 2, 2020February 28, 2026MORRISON, TRUDY G.reporter.nih.gov
Dissecting Yersinia Yop Targets in NeutrophilsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,883,504February 11, 2022January 31, 2027MECSAS, JOAN Creporter.nih.gov
Community-based Design and Evaluation of a Conversational Agent to Promote SARS-COV2 Vaccination in Black ChurchesNIHNational Institute on Minority Health and Health Disparities2021 to 2024$2,872,823April 23, 2021April 1, 2025BICKMORE, TIMOTHY W.reporter.nih.gov
Task B1C1: Vaccine and Treatment Evaluation Units (VTEU) Protocol Development and Implementation Natural History Challenge Study for InfluenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,862,138April 15, 2019November 30, 2024ORTIZ, JUSTINreporter.nih.gov
A New Class of Broad-Spectrum Antibacterial Agents to Treat Multi-Drug Resistant PathogensNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,858,436July 21, 2023June 30, 2027SEBAHAR, PAULreporter.nih.gov
Tfh dysfunction in HIV and AgingNIHNational Institute on Aging2021 to 2024$2,856,124September 30, 2020April 30, 2026PAHWA, SAVITAreporter.nih.gov
Virtual Patient Cohorts to Illuminate Immunologic Drivers of Influenza SeverityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,844,812June 1, 2022May 31, 2027SMITH, AMBER Mreporter.nih.gov
Molecular Mechanisms and In Vivo Impact of Tethered Mucin 1-Influenza Virus InteractionsNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,842,330January 15, 2021December 31, 2026SCULL, MARGARET ADELEreporter.nih.gov
Betacoronaviruses: activation and antagonism of host innate immune responsesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,828,524May 24, 2018April 30, 2028WEISS, SUSAN Rreporter.nih.gov
Molecular Determinants of Usual Interstitial Pneumonia (UIP)NIHNational Heart, Lung, and Blood Institute2022 to 2025$2,826,957April 1, 2022March 31, 2027SCHWARTZ, DAVID ALBERTreporter.nih.gov
Protective functions of influenza-specific lung-resident memory B cellsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,821,316June 16, 2020May 31, 2027RANDALL, TROY Dreporter.nih.gov
Central role of Caspase-8 in control of host tolerance and resistance mechanisms in pulmonary macrophage populations during severe respiratory infectionsNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,808,365August 15, 2023May 31, 2027JAMIESON, AMANDA Mreporter.nih.gov
Mechanisms of regulatory T cell-mediated recovery from severe viral pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,783,450March 1, 2020June 30, 2029SINGER, BENJAMIN DAVIDreporter.nih.gov
Yersinia Outer-Membrane-Vesicle Vaccines Against Pneumonic PlagueNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,776,243January 25, 2022December 31, 2026SUN, WEIreporter.nih.gov
Child Lung Development Following a Cookstove Intervention: Evidence from GRAPHSNIHNational Institute of Environmental Health Sciences2021 to 2025$2,763,681July 1, 2017February 29, 2028JACK, DARBYreporter.nih.gov
RNA:protein interactions that dictate the success of influenza virus infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,759,202February 2, 2022January 31, 2027MEHLE, ANDREWreporter.nih.gov
Modeling the Coupled Dynamics of COVID-19 Transmission and Protective BehaviorsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,758,288September 17, 2021August 31, 2027PARKER, ANDREWreporter.nih.gov
Defining the Fc-correlates of protection against influenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,753,246March 11, 2020February 28, 2026LINGWOOD, DANIELreporter.nih.gov
Systems-based pharmacologic modelling to elucidate beta-lactam clinical pharmacodynamics and define optimal dosing regimens in severe pneumoniaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,734,140July 11, 2022June 30, 2027RHODES, NATHANIEL JAMESreporter.nih.gov
High-throughput assays and small-molecule discovery of antiviral candidates targeting influenza hemagglutininNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,727,483May 1, 2021April 30, 2026WILSON, IAN Areporter.nih.gov
Sensing living P. aeruginosa using D-alanine derived radiotracersNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2024$2,693,051May 1, 2021January 31, 2026WILSON, DAVID Mreporter.nih.gov
Innate immune signaling and stress responseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,692,500March 15, 2016February 28, 2026KANNEGANTI, THIRUMALA-DEVIreporter.nih.gov
Influenza Attenuates Innate Pulmonary Host Defense against Invasive Pulmonary AspergillosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,690,414July 15, 2021June 30, 2027ROBINSON, KEVEN MARAreporter.nih.gov
Syndecan-1 suppression of lung inflammationNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,688,430April 25, 2022March 31, 2026CHEN, PETERreporter.nih.gov
Protein therapy to treat virus induced cardiopulmonary injuryNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,684,754June 6, 2022May 31, 2026MA, JIANJIEreporter.nih.gov
Nosocomial pneumonias impair cognitive functionNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,684,149April 1, 2018August 31, 2027LIN, MIKEreporter.nih.gov
Seasonal and universal Vaccination in aged populations with pre-existing immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,672,903May 21, 2021April 30, 2027KANG, SANG-MOOreporter.nih.gov
Amyloid-mediated cognitive dysfunction in bacterial pneumonia after TBINIHNational Institute on Aging2025$2,663,195September 15, 2025August 31, 2029WAGENER, BRANT Mreporter.nih.gov
Targeting Pneumococcal TransmissionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,658,920February 1, 2020January 31, 2026WEISER, JEFFREY NEALreporter.nih.gov
Macrorecombination in isolated cell pairs via natural genetic transformationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,657,698May 21, 2021April 30, 2027EDDINGTON, DAVIDreporter.nih.gov
Genetically modified pigs to model NKT cell immunity to influenza virus infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,654,780April 6, 2022March 31, 2027DRIVER, JOHNreporter.nih.gov
Monoclonal Antibody to Combat Pseudomonas AeruginosaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,646,807August 15, 2023July 31, 2028GOLDBERG, JOANNA Breporter.nih.gov
The interface between L. pneumophila manipulation of host endoplasmic reticulum and innate immune subterfugeNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,645,600February 20, 2020January 31, 2026ISBERG, RALPH R.reporter.nih.gov
Mechanisms of Pneumococcal Persistence During CarriageNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,644,208April 1, 1996June 30, 2029WEISER, JEFFREY NEALreporter.nih.gov
Quantifying Error Growth to Improve Infectious Disease Forecast AccuracyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,622,260June 9, 2021May 31, 2027SHAMAN, JEFFREY Lreporter.nih.gov
Balancing epithelial cell resistance and resilience to respiratory viral infectionsNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,621,215January 1, 2023December 31, 2027ORDOVAS-MONTANES, JOSE MANUELreporter.nih.gov
Development of a Mucosal Nanoemulsion-Adjuvanted RSV Vaccine using Recombinant Pre-Fusion F ProteinNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,617,783September 1, 2020December 31, 2025TRABBIC, KEVINreporter.nih.gov
Pandemrix and T Cell Immunology in NarcolepsyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,607,677May 13, 2021April 30, 2025MIGNOT, EMMANUEL Jreporter.nih.gov
GMP manufacturing and IND Filing of IN-002, a potent inhaled muco-trapping antibody therapy for Respiratory Syncytial VirusNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,605,456June 1, 2023May 31, 2027HUTCHINS, JEFF Treporter.nih.gov
A multivalent O-antigen bioconjugate vaccine for the prevention of Klebsiella pneumoniae infectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,591,387July 15, 2022July 31, 2027HARDING, CHRISTIANreporter.nih.gov
ETS-family Transcription Factor Mediated Control of Pulmonary Inflammation Induced by Influenza VirusesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,590,407February 1, 2019October 31, 2028HEATON, NICHOLAS Sreporter.nih.gov
Targeted genetic engineering of B cells to induce protective antibody responses to viral pathogensNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,577,835July 5, 2022June 30, 2027ADAIR, JENNIFER EILEENreporter.nih.gov
Innate immune-mediated control of pulmonary Legionella pneumophila infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,572,725November 16, 2015June 30, 2027SHIN, SUNNYreporter.nih.gov
Rapid, Breath Volatile Metabolite-Based Diagnosis, Species Identification, and Antibiotic Resistance Profiling in Bacterial PneumoniaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,571,160February 15, 2023January 31, 2028KOO, SOPHIAreporter.nih.gov
Rapid Manufacturing of a Universal Flu Vaccine Using TMV-conjugated Centralized AntigensNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,568,474June 1, 2020May 31, 2026WEAVER, ERIC Areporter.nih.gov
VACCINE ADJUVANT DISCOVERY PROGRAM (VADP)NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,547,484September 30, 2025September 29, 2026LEVY, OFERreporter.nih.gov
Engineered “muco-trapping” antibodies for inhaled therapy of parainfluenza and human metapneumovirus infectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,541,116September 19, 2022July 31, 2027LAI, SAMUELreporter.nih.gov
Engineering Protein Antigens and their Presentation from Multivalent ScaffoldsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,480,883July 7, 2023June 30, 2028KANE, RAVI S.reporter.nih.gov
Deciphering the Heterogeneous Response to Influenza by a Multi-Scale Systems ApproachNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,480,693July 14, 2022June 30, 2027FORST, CHRISTIANreporter.nih.gov
Lung leukocytes promote alveolar epithelial regeneration after severe injuryNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,469,157May 1, 2020April 30, 2026ARPAIA, NICHOLASreporter.nih.gov
Treatment of Inflammatory Complications of Respiratory InfectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,463,597June 20, 2022July 31, 2026LARK, MICHAEL WILLIAMreporter.nih.gov
New mouse model to better predict human immunity to influenza vaccination and infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,461,120August 1, 2021July 31, 2025MASOPUST, DAVIDreporter.nih.gov
Modeling the development, structure and regulation of T cell memoryNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,452,681March 1, 2011August 31, 2026YATES, ANDREWreporter.nih.gov
Dynamic regulatory network models of human response to influenza virusNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,434,869August 17, 2020May 31, 2026MARAZZI, IVANreporter.nih.gov
Functional and genetic constraints on influenza virus replication and fidelityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,431,062June 17, 2022May 31, 2027LAURING, ADAMreporter.nih.gov
hHv1 channels in neutrophils and the innate immune inflammatory responseNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,426,520August 5, 2022June 30, 2027GOLDSTEIN, STEVE A Nreporter.nih.gov
Targeting Estrogenic pathways in Tregs to promote ARDS resolutionNIHNational Heart, Lung, and Blood Institute2022 to 2024$2,413,250June 1, 2022May 31, 2026D'ALESSIO, FRANCO RAFAELreporter.nih.gov
Let-7b in Extracellular Vesicles Secreted by Bronchial Epithelial Cells Increases the Antibiotic Sensitivity of PseudomonasNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,409,204December 15, 2020November 30, 2025STANTON, BRUCE A.reporter.nih.gov
Predictive fitness models for influenza vaccine strain selectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,404,863January 13, 2022August 10, 2025LUKSZA, MARTAreporter.nih.gov
Structure and dynamics of RNA elements regulating viral aberrant RNA synthesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,396,295September 8, 2022August 31, 2027TE VELTHUIS, AREND JANreporter.nih.gov
SBIR: In vivo validation and IND-enabling development of MM004, a bispecific inhaled immunotherapy for RSV and MPVNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,380,033March 4, 2021February 28, 2026CONE, RICHARDreporter.nih.gov
Using three-dimensional protein networks to uncover immuno-modulatory molecular phenotypes in infectious diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,378,125August 1, 2021July 31, 2027DAS, JISHNUreporter.nih.gov
Fungal dysbiosis regulation of post-influenza bacterial pneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,376,545July 16, 2021June 30, 2025CHEN, PETERreporter.nih.gov
Improve Lung Regeneration Through Targeting Tuft Cells Following Viral InfectionNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,371,262August 20, 2021June 30, 2026QUE, JIANWENreporter.nih.gov
Defining the Interplay Between Viral Adaptation and Host ProteostasisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,362,578September 19, 2022July 31, 2027SHOULDERS, MATTHEW DONALDreporter.nih.gov
A prophylactic vaccine to prevent colonization by Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,345,744December 27, 2022November 30, 2027PICKING, WENDY L.reporter.nih.gov
Anticipating and rapidly responding to respiratory virus outbreaks with continuous air sampling in K-12 schoolsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,338,302January 18, 2023December 31, 2027O'CONNOR, DAVID H.reporter.nih.gov
Mechanisms of innate resistance to virus infectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,323,545February 1, 2017January 31, 2027YOUNT, JACOBreporter.nih.gov
Cardiac microlesion formation during invasive pneumococcal diseaseNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,308,740November 1, 2014May 31, 2030ORIHUELA, CARLOS Jreporter.nih.gov
Follistatin-like 1 Mediated Host Defense in Bacterial PneumoniaNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,305,697July 1, 2022June 30, 2027CAMPFIELD, BRIAN Treporter.nih.gov
IL-33 induced-lL-9 producing type 2 innate lymphoid cells in the regulation of acute lung injury after hematopoietic stem cell transplantation (HSCT) in pediatric patientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,303,969January 1, 2022June 30, 2026PACZESNY, SOPHIEreporter.nih.gov
Preclinical development of a synthetic lung surfactant dry powder aerosol for hypoxemia or acute respiratory distress syndrome patients receiving different modes of ventilation supportNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,301,184July 1, 2023June 30, 2027LONGEST, P. WORTHreporter.nih.gov
Novel, Self-Applied MicroArray Patch (MAP) of Zanamivir for Treatment of the FluNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,299,720August 16, 2024January 31, 2027LIPKA, ELKEreporter.nih.gov
Deciphering the role of peroxisomes in bacterial pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,298,625September 19, 2022July 31, 2027O'CONNOR, TAMARAreporter.nih.gov
Development of CM-IAV1 for Treatment of High-risk Pandemic InfluenzasNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$2,298,010April 25, 2022May 30, 2026COOPER, COLLEEN DOYLEreporter.nih.gov
Identifying Influenza Virus Infection Severity and Outcome Signatures Through Artificial Intelligence-driven AnalysesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,286,566July 7, 2022June 30, 2028DUPONT, CHRISTOPHER L.reporter.nih.gov
Prevalence effects in visual search: Theoretical and practical implicationsNIHNational Eye Institute2021 to 2025$2,283,459April 1, 2007June 30, 2029WOLFE, JEREMY Mreporter.nih.gov
Biology of Lymphangiogenesis in the Adult LungNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,281,864July 1, 2022June 30, 2027JONES, MATTHEW ROBERTreporter.nih.gov
Protection and Immunity after Polyanhydride Nanoparticle Vaccination against Avian Influenza A VirusNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,280,238November 14, 2022October 31, 2027LEGGE, KEVIN Lreporter.nih.gov
Roles of tissue-resident helper T cells in mucosal immunity against influenzainfectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,276,812February 1, 2022April 30, 2025SUN, JIEreporter.nih.gov
LOX-1 as a protective countermeasure in response to lung infectionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,274,599June 15, 2023May 31, 2027QUINTON, LEEreporter.nih.gov
Optimizing a Universal Influenza Subunit Nano/Microparticulate VaccineNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,261,035January 15, 2020December 31, 2025AINSLIE, KRISTY Mreporter.nih.gov
Bioactivities of pneumococcal cell wall in neuropathogenesisNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,255,100November 4, 2016January 31, 2027TUOMANEN, ELAINE Ireporter.nih.gov
Elucidating the roles of alveolar macrophage inflammation and self renewal during influenza infectionNIHNational Institute on Aging2021 to 2025$2,252,254August 15, 2020April 30, 2030SUN, JIEreporter.nih.gov
Role of spatial structure in shaping viral population diversity and evolutionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,238,488August 17, 2020July 31, 2025LOWEN, ANICE Creporter.nih.gov
Mechanistic modeling of the innate immune responses of the human lung to understand the inter-individual heterogeneity of COVID-19 pneumoniaNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,227,734July 1, 2023June 30, 2027MEHRAD, BORNAreporter.nih.gov
Functional Implications of Tfh Cell Heterogeneity after InfectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,219,856January 24, 2022December 31, 2026RANDALL, TROY Dreporter.nih.gov
The role of ACE2 in Influenza viral infection mediated immune compromise and subsequent bacterial lung infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,219,353May 15, 2020April 30, 2026JIA, HONGPENGreporter.nih.gov
Interplay between influenza virus and S1P-metabolizing enzymesNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,218,924June 10, 2021May 31, 2027HAHM, BUMSUKreporter.nih.gov
Regulation of the interferon lamda receptor by influenzaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,215,117April 1, 2006June 30, 2026MALLAMPALLI, RAMA Kreporter.nih.gov
Development of vaccine approaches to elicit broadly protective influenza-specific immune responses in infantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,208,932August 5, 2020July 31, 2026ALEXANDER-MILLER, MARTHA ANNreporter.nih.gov
Loss of Endothelial S1PR1 Drives Post-Influenza Pulmonary FibrosisNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,206,371June 15, 2023May 31, 2028KNIPE, RACHEL Sreporter.nih.gov
Identification and characterization of effector memory B cell populations that dominate memory responses to subsequent influenza infection and vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,206,266August 3, 2020July 31, 2025LUND, FRANCES E.reporter.nih.gov
Coordinated regeneration of lung epithelial and endothelial compartmentsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,201,693August 20, 2022July 31, 2026VAUGHAN, ANDREWreporter.nih.gov
Control of influenza virus induced type I interferon signaling during pregnancyNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,200,686November 1, 2022October 31, 2027HEATON, NICHOLAS Sreporter.nih.gov
Forecasting influenza evolution on a heterogeneous immune landscapeNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,197,907February 15, 2022January 31, 2028BEDFORD, TREVOR BCreporter.nih.gov
Novel mechanisms of Alveolar Macrophage-Dependent Antifungal Innate ImmunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,192,702January 8, 2020December 31, 2025WRIGHT, TERRY Wreporter.nih.gov
Impact of inflammatory lipids on Yersinia pestis infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,171,406July 14, 2023June 30, 2027LAWRENZ, MATTHEW Breporter.nih.gov
Automated chemo-enzymatic synthesis of N-glycans for host-pathogen interactionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,169,230June 1, 2022May 31, 2027BOONS, GEERT-JANreporter.nih.gov
Developmental Exposures to Arsenic: Pneumonia, Immunity, and Microbiomes (DEAPIM)NIHNational Institute of Environmental Health Sciences2023 to 2025$2,157,462February 5, 2022December 31, 2026PARVEZ, MUHAMMAD Freporter.nih.gov
Effective Primary care practices that Enhance Recovery Trajectories after pneumonia (EXPERT)NIHNational Heart, Lung, and Blood Institute2023 to 2025$2,148,392September 15, 2023June 30, 2028IWASHYNA, THEODORE Jreporter.nih.gov
Genetic Contributors to the Impact of Sex on Heterogeneity in Flu InfectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,125,850July 11, 2022June 30, 2027KO, DENNIS CHUN-YONEreporter.nih.gov
Linking SARS-CoV-2 Aerosol Viability and Environmental Factors in Healthcare SettingsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,121,919August 17, 2023July 31, 2027KELLY, KERRYreporter.nih.gov
Influenza & COVID Obstetric and Perinatal Epidemiology Study in IndiaNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,121,321September 23, 2022August 31, 2027HIBBERD, PATRICIA Lreporter.nih.gov
THE IMPACT OF ADVANCED AGE AND SEX ON HUMORAL IMMUNITY TO STREPTOCOCCUS PNEUMONIAENIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,121,108September 1, 2022August 31, 2027HAAS, KAREN Mreporter.nih.gov
mRNA-encoded Cas13 as a pan-respiratory antiviralNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,120,971January 23, 2023December 31, 2027SANTANGELO, PHILIP Jreporter.nih.gov
Structure and Function of Legionella pneumophila Lysine MethyltransferasesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,118,862March 21, 2022February 28, 2027TRIEVEL, RAYMOND Creporter.nih.gov
Macrophage-targeting Nanoplatforms as Immunotherapy against Pulmonary InfectionsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$2,117,352July 1, 2017November 30, 2028SAILOR, MICHAEL Jreporter.nih.gov
TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung InjuryNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,097,481February 1, 2021January 31, 2027SCHERAGA, RACHEL GREENBERGreporter.nih.gov
Interleukin-27 in host response to Legionella infectionNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,096,982July 1, 2023June 30, 2027BOSMANN, MARKUSreporter.nih.gov
Alveolar responses to viral lung infectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,088,426June 20, 2022May 31, 2027HOOK, JAIME LYNNreporter.nih.gov
IDENTIFICATION AND CHARACTERIZATION OF T CELL EPITOPES FROM BACTERIAL PATHOGENS CAUSING PNEUMONIANIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,079,792September 30, 2025September 29, 2026PETERS, BJOERNreporter.nih.gov
Biophysical studies of viral membrane fusion proteinsNIHNational Institute of General Medical Sciences2022 to 2025$2,067,810July 1, 2022June 30, 2027MUNRO, JAMES Breporter.nih.gov
Transcriptional Regulation of Migrating Neutrophils during PneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,062,500July 1, 2021June 30, 2027TRABER, KATRINAreporter.nih.gov
Integrating measurements of immune escape and in vitro replication with computational models to understand and predict the antigenic evolution of seasonal A/H3N2 influenza virusesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,056,935February 7, 2022January 31, 2027SMITH, DEREK JAMESreporter.nih.gov
Regulation of the host immune response to influenza by the checkpoint receptor Tim3NIHNational Heart, Lung, and Blood Institute2021 to 2024$2,054,835May 1, 2020April 30, 2026CHO, JOSALYN Lreporter.nih.gov
Pharmacokinetics analysis from first-in-human study of IN-002, a potent inhaled muco-trapping antibody therapy for RSVNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,049,871June 21, 2024May 31, 2027SCOTT, DAVID Wreporter.nih.gov
IND-enabling development for IN-003, an inhaled mAb therapy against human metapneumovirus infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$2,049,821May 15, 2024April 30, 2027HUTCHINS, JEFF Treporter.nih.gov
Influenza A Inhibits TH17 Host Defense Against Bacterial PneumoniaNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,049,603January 1, 2012March 31, 2026ALCORN, JOHN Freporter.nih.gov
Biophysical constraints of influenza neuraminidase evolutionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,049,096June 28, 2022May 31, 2027WU, NICHOLAS C.reporter.nih.gov
Sequence-function relationship of influenza broadly neutralizing antibodiesNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,039,386January 25, 2022December 31, 2026WU, NICHOLAS C.reporter.nih.gov
Cellular and molecular mechanisms of alveolar repairNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,019,414August 1, 2023May 31, 2027DESAI, TUSHAR JASUBHAIreporter.nih.gov
Adjuvant Development of the TLR4 Ligand BECC470s For Use in Influenza, S. aureus, and P. aeruginosa VaccinesNIHNational Institute of Allergy and Infectious Diseases2025$2,018,199September 30, 2023September 29, 2026SORENSON, GREGORYreporter.nih.gov
Consequences of Direct Viral-Bacterial InteractionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,014,549January 5, 2022December 31, 2026ROSCH, JASON W.reporter.nih.gov
An immunodominance-based Pan-Pneumovirus vaccine for protection against RSV and hMPVNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$2,007,500June 6, 2023May 31, 2028MOUSA, JARRODreporter.nih.gov
Pneumocystis: Macrophage & Epithelial ActivationNIHNational Heart, Lung, and Blood Institute2021 to 2025$2,005,500July 10, 1993January 31, 2027LIMPER, ANDREW Hreporter.nih.gov
Early Responses to Influenza A Virus Replication In VivoNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,004,034March 1, 2020February 28, 2026LANGLOIS, RYANreporter.nih.gov
A new class of antibiotic to address Antimicrobial ResistanceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,999,995May 1, 2024April 30, 2027TESTA, CHARLESreporter.nih.gov
Megakaryocyte regulation by the gut microbiomeNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,980,652June 1, 2023March 31, 2027ZENG, MELODY Yreporter.nih.gov
Lung Macrophage Memory Development and Responses in Secondary Pneumonia and SepsisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,972,366August 27, 2021July 31, 2026MISHRA, BIBHUTI BHUSANreporter.nih.gov
The role of neutrophils in the age-driven decline in anti-pneumococcal vaccine responsesNIHNational Institute on Aging2021 to 2025$1,966,375September 30, 2021May 31, 2027BOU GHANEM, ELSAreporter.nih.gov
Mechanism of Protein Synthesis and Translational ControlNIHNational Institute of General Medical Sciences2021 to 2025$1,962,066June 1, 2021May 31, 2027JOSEPH, SIMPSONreporter.nih.gov
Molecular regulation of protective CD8 immunity against influenza infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,956,077February 10, 2015April 30, 2025SUN, JIEreporter.nih.gov
Combining innovative molecular adjuvanting approaches with novel adenoviral vector delivery to generate a universal influenza vaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,952,609July 1, 2022June 30, 2027COUGHLAN, LYNDAreporter.nih.gov
Tissue niches for ILC3 development in newborn's lungNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,949,066January 1, 2021March 14, 2025DESHMUKH, HITESHreporter.nih.gov
Unraveling the Viral Infection Pathway with Virus-locked ObservationNIHNational Institute of General Medical Sciences2021 to 2025$1,947,117August 15, 2017May 31, 2027WELSHER, KEVINreporter.nih.gov
Role of preexisting immunity on airborne transmission of influenza virusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,945,314February 1, 2023January 31, 2027LAKDAWALA, SEEMA S.reporter.nih.gov
Microbiota Regulation of Pulmonary Complications Post-HCTNIHNational Heart, Lung, and Blood Institute2021 to 2025$1,941,600September 20, 2021August 31, 2026ZHOU, XIAOFENGreporter.nih.gov
Improved Therapeutics and Diagnostics for Pneumocystis PneumoniaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,932,841February 1, 2016October 31, 2026KOLLS, JAY Kreporter.nih.gov
Impact of Aging on Oxysterol Regulation of Alveolar Macrophage Function during S. pneumoniaeNIHNational Institute on Aging2023 to 2025$1,932,027September 1, 2023May 31, 2028STOUT DELGADO, HEATHER WINONAreporter.nih.gov
Molecular mechanisms underlying organ penetration in disseminated pneumococcal infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,924,214November 1, 2022October 31, 2027ORIHUELA, CARLOS Jreporter.nih.gov
Skin vaccination and generation of protective lung-tropic memory T cellsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,906,147December 18, 2023October 31, 2028KUPPER, THOMAS S.reporter.nih.gov
Harnessing targeted IL-2 to reduce immunopathology and enhance immunity against respiratory virus infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,900,000September 22, 2021August 31, 2027STRUTT, TARA MARLENEreporter.nih.gov
Advanced testing of a hexavalent adjuvanted influenza vaccine platform for dose sparing, multiplexing, and rapid deploymentNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,899,426June 1, 2024May 31, 2027KUTSCHER, HILLIARDreporter.nih.gov
Functional diversity of lung pericytes in lung injuryNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,899,368December 15, 2022November 30, 2027HUNG, CHI Freporter.nih.gov
Elucidating the role of type I interferon signaling and macrophage-derived inflammation in the juvenile host with viral pneumoniaNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,898,753May 8, 2023February 28, 2027COATES, BRIA Mreporter.nih.gov
Control of antiviral memory CD8+ T cell longevity by extracellular ATP sensingNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,894,856July 1, 2022June 30, 2027BORGES DA SILVA, HENRIQUEreporter.nih.gov
Harnessing type I interferon to promote lung-resident memory CD4 T cell immunity against influenzaNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,893,259June 21, 2022May 31, 2027MCKINSTRY, KARL KAIreporter.nih.gov
Investigating protective adaptive immune responses to influenza antigens using human tonsil organoidsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,890,792June 1, 2023May 31, 2028WAGAR, LISAreporter.nih.gov
A new mucosal adjuvant for augmenting influenza vaccines in elderlyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,887,393May 24, 2021April 30, 2027WU, MEI Xreporter.nih.gov
Real-time tracking of virus evolution for vaccine strain selection and epidemiological investigationNIHNational Institute of General Medical Sciences2021 to 2025$1,886,759August 23, 2016May 31, 2026BEDFORD, TREVOR BCreporter.nih.gov
7HP349, an oral integrin activator to augment effectiveness of pre-exposure influenza vaccinationNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,881,701April 26, 2023March 31, 2026MARATHI, UPENDRAreporter.nih.gov
Markers and regulation of regulatory CD8+ T cells during influenza-induced lung immunopathologyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,878,277July 1, 2021June 30, 2027HUANG, WEISHANreporter.nih.gov
Innate NLRC4 signaling controls adaptive immune responsesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,874,689June 20, 2023May 31, 2028SUTTERWALA, FAYYAZ S.reporter.nih.gov
Colistin resistance in extensively drug-resistant Gram-negative pathogensNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,869,812March 15, 2014March 31, 2025DOI, YOHEIreporter.nih.gov
Context dependent amino acid availability and sensing determines humoral immunityNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,869,187February 10, 2022January 31, 2027ZENG, HUreporter.nih.gov
Understanding and targeting fibroblast activation in influenza-triggered lung inflammation and post-viral diseaseNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,866,950September 1, 2023August 31, 2028BOYD, DAVID FIELDINGreporter.nih.gov
Targeting Influenza A Virus by a Carbohydrate-inspired StrategyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,866,200September 18, 2019December 31, 2027WONG, CHI-HUEYreporter.nih.gov
Common Post-Infectious Premature Epigenetic AgingNIHNational Institute on Aging2023 to 2025$1,844,091August 15, 2023April 30, 2028DINARDO, ANDREW Rreporter.nih.gov
Memory CD8 T cell localization and protection from influenzaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,841,052November 1, 2014December 31, 2024HARTY, JOHN Treporter.nih.gov
Siderophore based molecular imaging of pulmonary infectionsNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,833,928July 1, 2023June 30, 2028KOTAGIRI, NALINIKANTHreporter.nih.gov
Antibiotic tolerance: membraneless organelles and autolysin regulationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,820,000May 5, 2022April 30, 2027TUOMANEN, ELAINE Ireporter.nih.gov
Addressing Vaccine AcceptaNce in Carceral Settings through Community Engagement (ADVANCE)NIHNational Institute on Minority Health and Health Disparities2022 to 2024$1,811,735September 26, 2022December 31, 2026PUGLISI, LISA BALZANOreporter.nih.gov
Lead optimization of a novel cyclic aryl-indole efflux pump inhibitor (EPI) series in combination with levofloxacin against Pseudomonas aeruginosaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,799,789May 1, 2024April 30, 2027PARHI, AJIT Kreporter.nih.gov
Virulence Factor at the Interface of Viral and Cellular mRNA Nuclear ExportNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,776,477May 6, 2020April 30, 2026FONTOURA, BEATRIZ MAreporter.nih.gov
Endolysins as tools to eradicate pneumococcal biofilms and development ofprotective immunityNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,770,586December 9, 2022November 30, 2027GONZALEZ-JUARBE, NORBERTOreporter.nih.gov
Molecular Mechanisms Regulating Bacterial Two-component Signaling SystemsNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,766,612February 8, 2023January 31, 2028FUENTES, ERNESTO JORGEreporter.nih.gov
Regulation Of Lung Immunity By Antibody GlycosylationNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,761,927February 13, 2024December 31, 2028WANG, TAIAreporter.nih.gov
Adrenergic control of circadian rhythms in CD8 T cells responding to influenzaNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,731,396July 1, 2023June 30, 2028FARRAR, JOHN DAVIDreporter.nih.gov
Leveraging community-based behavioral health to increase vaccine uptake in Latinx adults with mental illnessNIHNational Institute of Nursing Research2022 to 2024$1,714,097September 26, 2022March 10, 2025DAVISON, KIRSTENreporter.nih.gov
Vaccination responses in lung transplant recipientsNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,708,641August 5, 2022July 31, 2027NICOLLS, MARK ROBERTreporter.nih.gov
Mechanism and targeting of inflammasome activation in lung inflammation and injuryNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,696,153February 16, 2023January 31, 2028LIU, GANGreporter.nih.gov
A Flexible High-Throughput Immunological Assay to Support Next-Generation Influenza Vaccine StudiesNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,679,190May 3, 2023April 30, 2026SIGAL, GEORGE Breporter.nih.gov
Legionella effectors reveal novel signaling function for the ribosome quality control (RQC) pathwayNIHNational Institute of General Medical Sciences2021 to 2024$1,677,236June 15, 2016May 31, 2025MUKHERJEE, SHAERIreporter.nih.gov
Mechanisms of platelet reprogramming during influenza infectionNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,675,000July 1, 2020June 30, 2025KOUPENOVA, MILKAreporter.nih.gov
A redox-sensitive switch in the macrophage nucleus regulates acute phase inflammatory injuryNIHNational Heart, Lung, and Blood Institute2022 to 2024$1,671,361June 1, 2022May 31, 2026BONINI, MARCELO G.reporter.nih.gov
Text4Vax: Understanding the Implementation of Informational Text Messages for Pediatric Influenza VaccinesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,667,321April 15, 2024February 29, 2028STOCKWELL, MELISSA Sreporter.nih.gov
Use of Clinical Samples to Identify Influenza Virus Antigenic VariantsNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,659,372July 17, 2019June 30, 2025WAN, XIUFENG HENRYreporter.nih.gov
PspA binds necroptotic cells to cause disease and transmitNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,641,325September 24, 2020August 31, 2025ORIHUELA, CARLOS Jreporter.nih.gov
Impact of nucleotide metabolism on bacterial clearanceNIHNational Institute of General Medical Sciences2022 to 2025$1,637,144August 15, 2022July 31, 2027RIQUELME COLET, SEBASTIAN ALEJANDROreporter.nih.gov
BE IMMUNE: Behavioral Economics to Improve and Motivate vaccination Using Nudges through the EHRNIHNational Institute on Aging2022 to 2024$1,628,541August 15, 2020August 31, 2025MEHTA, SHIVAN JATINreporter.nih.gov
A Phase II Study Evaluating the Safety and Efficacy of Whole-Cell Pneumococcal Vaccine (wSp) in Reducing Nasopharyngeal Colonization by Streptococcus pneumoniae in Young ChildrenNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,616,462March 15, 2024February 29, 2028PICHICHERO, MICHAEL Ereporter.nih.gov
Understanding alterations to mucus composition and function in asthmaNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,614,918July 1, 2022April 30, 2027DUNCAN, GREGGreporter.nih.gov
Immunogenetics of COVID-19 Immune ResponseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,614,396August 1, 2024July 31, 2029KENNEDY, RICHARD Breporter.nih.gov
Liposomal Encapsulation Vaccine Design for Pneumococcal Disease in Aged SubjectsNIHNational Institute on Aging2022 to 2025$1,602,868August 4, 2022April 30, 2027PFEIFER, BLAINE A.reporter.nih.gov
Inflammatory mechanisms responsible for the development of multiple organ dysfunction in pediatric patients following allogeneic blood and marrow transplantation (BMT).NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$1,598,857February 1, 2020January 31, 2026COOKE, KENNETH Rreporter.nih.gov
Solitary chemosensory / tuft cells in lung regeneration and inflammationNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,597,401June 1, 2020May 31, 2025VAUGHAN, ANDREWreporter.nih.gov
Novel Biamyxins targeting multidrug resistant Gram-negative bacterial infectionsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,596,741July 2, 2024June 30, 2029ZHAO, YANANreporter.nih.gov
The Role of Eicosanoid-PPAR axis in Exacerbating Post-Influenza Staphylococcus aureus Super-infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,594,729January 21, 2022December 31, 2026TAM, VINCENTreporter.nih.gov
DC-subset-tailored vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,560,000June 17, 2020May 31, 2026IGYARTO, BOTOND Zreporter.nih.gov
Immune mechanisms of influenza‐induced exacerbation of atherosclerosisNIHNational Heart, Lung, and Blood Institute2021 to 2024$1,558,220August 15, 2020July 31, 2025GOPAL, RADHAreporter.nih.gov
Acquired CFTR Dysfunction in Alcohol-related Lung PathologyNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2024$1,544,404January 1, 2020December 31, 2024RAJU, S.VAMSEEreporter.nih.gov
Impact of intra-host population structure on influenza virus antigenic evolutionNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,543,925December 9, 2021November 30, 2026LOWEN, ANICE Creporter.nih.gov
Investigation of host glycan requirements for the transmission of influenza viruses at the human-animal interfaceNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,541,846July 26, 2024June 30, 2029MANICASSAMY, BALAJIreporter.nih.gov
Broad spectrum protection and immune responses induced by an NP-based universal influenza vaccine in heterologous NHP challenge modelNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,540,227September 26, 2023August 31, 2026NICOLAS, FLORENCEreporter.nih.gov
Novel role for protein kinase D in airway inflammation and antiviral immunityNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,540,000March 13, 2020February 28, 2026GEORAS, STEVE Nreporter.nih.gov
Acidosis in pulmonary endothelial injury and repairNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,540,000February 1, 2022January 31, 2027LEE, JI YOUNGreporter.nih.gov
Understanding evasion of cell intrinsic innate immunity in viral populations with high rates of replicative failureNIHNational Institute of General Medical Sciences2022 to 2025$1,535,710August 1, 2022May 31, 2027RUSSELL, ALISTAIR Breporter.nih.gov
1/2 WIN Ratio Analysis to Determine a Strategy of Non-Invasive SUpport for Respiratory Failure in the EmeRgency Department (WINDSURFER)NIHNational Heart, Lung, and Blood Institute2025$1,535,439September 15, 2025December 31, 2026WANG, HENRY E.reporter.nih.gov
Defective Zn Homeostasis impairs host defense against pneumococcal pneumoniaNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,534,270December 22, 2021November 30, 2026KNOELL, DAREN LEEreporter.nih.gov
Fibrin in the Infected LungNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,530,164February 15, 2024January 31, 2028MIZGERD, JOSEPH Preporter.nih.gov
A NOVEL STRATEGY TO INHIBIT SARS-COV-2 INFECTION AND COVID-19NIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,525,325June 13, 2024April 30, 2029GALLAY, PHILIPPE ANDREreporter.nih.gov
Serological Biomarkers for CoccidioidomycosisNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,518,970June 7, 2021May 31, 2026MAGEE, D MITCHELLreporter.nih.gov
Uncovering and understanding the many functions of ICAM-1 in the lungs during homeostasis and innate immune responsesNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,518,050August 26, 2024May 31, 2028DOERSCHUK, CLAIRE Mreporter.nih.gov
Dual oxidase and lactoperoxidase in influenza infectionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,510,000February 19, 2020January 31, 2025RADA, BALAZSreporter.nih.gov
E3 Ligase-Mediated Immunosuppression in Acute Lung InjuryNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,507,608February 1, 2010June 30, 2026MALLAMPALLI, RAMA Kreporter.nih.gov
Predictive Modeling of Estradiol Effects and Sex Differences on Immunopathology during Influenza InfectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,502,325June 18, 2024May 31, 2029SHOEMAKER, JASON EDWARDreporter.nih.gov
Metal-binding Isosteres for Influenza Endonuclease Inhibitors and BeyondNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,482,645April 1, 2020March 31, 2026COHEN, SETH Mreporter.nih.gov
Novel coenzyme Q6 variant reveals non-immune determinants of survival during pneumococcal sepsisNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,481,057August 26, 2024July 31, 2028MORLEY, SHARON CELESTEreporter.nih.gov
Complement-mediated anti-pneumococcal functions of C-reactive proteinNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,480,000February 5, 2020January 31, 2026SINGH, SANJAY KUMARreporter.nih.gov
Development of broadly-protective vaccines for influenza B virusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,475,893July 1, 2023June 30, 2027KAWAOKA, YOSHIHIROreporter.nih.gov
Airway Prevotella enhance innate immune-mediated protection against lung infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,475,007March 20, 2023February 29, 2028CLARK, SARAH Ereporter.nih.gov
Structures and Dynamics of Proton and Cation-Dependent Channels and TransportersNIHNational Institute of General Medical Sciences2021 to 2024$1,474,187September 30, 2009June 30, 2025HONG, MEIreporter.nih.gov
Reducing Infection Susceptibility by Immune Function Restoration in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,459,520July 1, 2020June 30, 2025SCHWAB, JANreporter.nih.gov
Disease Mechanisms of Prenatal and Pediatric Acquired HydrocephalusNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,458,488April 1, 2020March 31, 2026CONOVER, JOANNE Creporter.nih.gov
Soluble adenylyl cyclases in lung endothelial tauopathyNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,451,396March 20, 2023February 28, 2027STEVENS, TROYreporter.nih.gov
Effects of Vaccination on Acute and Post-Acute Respiratory Viral Infection Outcomes in Solid Organ Transplant RecipientsNIHNational Institute of Allergy and Infectious Diseases2025$1,442,898June 13, 2025May 31, 2030WERBEL, WILLIAMreporter.nih.gov
Motivational Interviewing Training to Promote COVID-19 and Influenza Vaccination (MI-VAX): What Providers Need and Patients WantNIHNational Institute on Minority Health and Health Disparities2024 to 2025$1,432,670June 27, 2024January 31, 2029FISHER, KIMBERLYreporter.nih.gov
Inflammatory Organ Injury after Pneumonia-Derived SepsisNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,430,432July 1, 2024May 31, 2029JEYASEELAN, SAMITHAMBYreporter.nih.gov
NK cell inflammation resolution circuits in pediatric RSV infectionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,426,494December 1, 2023November 30, 2028DUVALL, MELODY G.reporter.nih.gov
Antibody mediated immunity against Klebsiella pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,424,123December 1, 2023October 31, 2028HARRIS, JASON Breporter.nih.gov
Endothelial antigen presentation to T cells as a pathogenic mechanism in influenza-induced acute lung injuryNIHNational Heart, Lung, and Blood Institute2022 to 2025$1,412,604March 15, 2021February 28, 2027ZHANG, LIANGHUIreporter.nih.gov
Airway metabolites shape susceptibility to pneumoniaNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,408,116April 1, 2024March 31, 2028PRINCE, ALICE Sreporter.nih.gov
Sphingolipid signaling in the endothelium during viral host defenseNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,405,202January 1, 2024December 31, 2027HLA, TIMOTHY TUNreporter.nih.gov
Negative regulation of innate immunity in influenza virus infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,396,060November 13, 2023October 31, 2028LI, JIAN-DONGreporter.nih.gov
Overcome immunodominance to support the development of universal influenza vaccinesNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,395,922August 28, 2024June 30, 2029LUO, WEIreporter.nih.gov
Longitudinal dynamics of protection after influenza infection and vaccinationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,395,852July 1, 2019June 30, 2025COBEY, SARAHreporter.nih.gov
Adenoviral Vector-based Pandemic Influenza VaccineNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,393,690July 1, 2005April 30, 2028MITTAL, SURESH Kreporter.nih.gov
Real-time predictive modeling for public health departments to control infectious diseasesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,389,825July 1, 2023July 31, 2027LO, NATHANreporter.nih.gov
Epitope and mechanistic correlates of broadly protective human antibodies for pneumococcal infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,369,933November 1, 2022October 31, 2028MOUSA, JARRODreporter.nih.gov
Shifting immunodominance of humoral immunity against influenza virusesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,354,521August 22, 2023July 31, 2028GUTHMILLER, JENNAreporter.nih.gov
High resolution profiling and computational modeling of influenza virus-immune dynamics during natural infectionNIHNational Institute of Allergy and Infectious Diseases2025$1,352,292February 1, 2025January 31, 2030BROOKE, CHRISTOPHER BYRONreporter.nih.gov
The role of Bik in the replication and severity of influenza A virusNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$1,345,904January 1, 2021December 31, 2026MEBRATU, YOHANNES AFEWORKreporter.nih.gov
Dime la VerDAD (Verify, Debunk, and Disseminate)NIHNational Institute on Minority Health and Health Disparities2023 to 2024$1,339,601July 10, 2023September 15, 2024DEL RIOS, MARINAreporter.nih.gov
Vaccine immunity and inflammation in the aging person living with HIVNIHNational Institute on Aging2024 to 2025$1,337,478July 15, 2024June 30, 2029FROSCH, ANNE ELIZABETH PARKERreporter.nih.gov
A universal intranasal nanoengineered therapy against airborne RNA virusesNIHNational Institute of Biomedical Imaging and Bioengineering2024 to 2025$1,328,784July 3, 2024April 30, 2028MAHAJAN, VINAY SUBHASHreporter.nih.gov
Synthetic multi-component influenza vaccines to elicit broad immunityNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,325,514December 19, 2023October 31, 2028BOONS, GEERT-JANreporter.nih.gov
B and Tfh cell dynamics underlying durable antibody responses to flu vaccine in childrenNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,297,795April 1, 2024February 28, 2029SINGH, HARINDERreporter.nih.gov
Structure-guided neutralizing antibodies developed using EpiVolve technologyNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,291,874May 5, 2023May 31, 2026LI, XIAOFENGreporter.nih.gov
Novel strategies to mitigate cardiac damage and dysfunction following invasive pneumococcal diseaseNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,289,472May 25, 2024June 1, 2025LAL, HINDreporter.nih.gov
Advancing our knowledge of viral membrane fusion and of IDP-membrane interactions by ESRNIHNational Institute of General Medical Sciences2023 to 2025$1,283,934February 1, 2023January 31, 2028FREED, JACK Hreporter.nih.gov
Intersection of Severe Respiratory Infection and Viral LatencyNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,280,794June 12, 2024April 30, 2029STEED, ASHLEYreporter.nih.gov
Small viral RNAs as determinants of influenza A virus pathogenesisNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,271,250February 4, 2020January 31, 2026TENOEVER, BENJAMIN R.reporter.nih.gov
Glypicans in Bacterial Lung InfectionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,247,722April 1, 2024March 31, 2028PARK, PYONG WOOreporter.nih.gov
Towards a predictive understanding of influenza immunity through experimental data integration, iterative model development, and rigorous assessment of model qualityNIHNational Institute of Allergy and Infectious Diseases2025$1,246,617December 19, 2024November 30, 2029PETERS, BJOERNreporter.nih.gov
Impact of Senolytics on Aged Vaccine ResponsesNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,244,166November 1, 2022October 31, 2027BARTLEY, JENNAreporter.nih.gov
Mechanisms of hypervirulent Klebsiella pneumoniae gastrointestinal colonization and disseminationNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$1,240,075June 14, 2023May 31, 2025ZAFAR, MUHAMMAD AMMARreporter.nih.gov
Immune signatures of vaccine responses in children with sickle cell diseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,228,468December 1, 2023October 31, 2028YILDIRIM, INCI BURCINreporter.nih.gov
Mitochondrial metabolism controls alveolar epithelial cell fateNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,227,550September 1, 2024August 31, 2029HAN, SEUNGHYEreporter.nih.gov
Computational Models of Adaptive Immunity to InfluenzaNIHNational Institute of Allergy and Infectious Diseases2025$1,225,986January 23, 2025December 31, 2029COBEY, SARAHreporter.nih.gov
Effects of wildfire smoke on respiratory antiviral defense responsesNIHNational Institute of Environmental Health Sciences2024 to 2025$1,217,903August 10, 2024May 31, 2029REBULI, MEGHAN ELIZABETHreporter.nih.gov
Host dependence of influenza A virus spatio-temporal dynamicsNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$1,214,178December 5, 2016August 31, 2029LOWEN, ANICE Creporter.nih.gov
Defining the four major routes of MHC class II antigen processing and presentation with influenza antigensNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,213,296June 1, 2024April 30, 2029EISENLOHR, LAURENCE CRANEreporter.nih.gov
Identifying critical determinants of vaccine-induced cellular and humoral immunity from birth through childhood in HIV-exposed and unexposed childrenNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,202,470November 20, 2023October 31, 2027SLYKER, JENNIFER ANNreporter.nih.gov
HIV-1 Env gp160 maturation in the Golgi apparatusNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,199,250May 10, 2023April 30, 2028ZHENG, YONG-HUIreporter.nih.gov
Unravelling highly pathogenic influenza virus emergenceNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,196,018August 1, 2023July 31, 2028RICHARD, MATHILDEreporter.nih.gov
Machine Learning to Modulate Influenza ImmunityNIHNational Institute of Allergy and Infectious Diseases2025$1,195,056May 19, 2025April 30, 2030MEILER, JENSreporter.nih.gov
Extrafollicular B cell response regulation during influenza infectionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,193,272June 10, 2024May 31, 2029BAUMGARTH, NICOLEreporter.nih.gov
How Distinct Age-Associated B Cell Subsets Can Protect the Aged from InfluenzaNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,172,336August 19, 2024July 31, 2029SWAIN, SUSAN Lreporter.nih.gov
Influenza Modeling of Correlates of Protection for Optimal Immune Dynamics and Evolution.NIHNational Institute of Allergy and Infectious Diseases2025$1,171,832December 24, 2024November 30, 2029MEDINA SILVA, RAFAEL A.reporter.nih.gov
Floss: a novel method for oral mucosal vaccinationNIHNational Institute of Dental & Craniofacial Research2024 to 2025$1,169,988August 1, 2024April 30, 2029GILL, HARVINDER SINGHreporter.nih.gov
The MUltidimenSional phenotyping In Critical care (MUSIC) Consortium: A pathway to precision medicine at the bedsideNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,162,536May 1, 2023April 30, 2029WARE, LORRAINE Breporter.nih.gov
Genetic and biophysical mechanisms that control influenza virus cellular multiplicity of infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,155,422February 16, 2023January 31, 2028VAHEY, MICHAEL Dreporter.nih.gov
Pathogenic role of IL-17 response in Streptococcus pneumoniae nasopharyngeal pathogenesis during an influenza virus co-infectionNIHNational Institute of Allergy and Infectious Diseases2022 to 2024$1,152,158December 3, 2019November 30, 2025KHAN, NADEEMreporter.nih.gov
Protein Transport Across Membrane by Bacterial PathogensNIHNational Institute of General Medical Sciences2023 to 2025$1,149,661July 7, 2023April 30, 2028DURIE, CLARISSA LYNNreporter.nih.gov
Defining the Role of the Plasminogen Activator Protease in the Early Events that Establish Primary Pneumonic PlagueNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,149,651May 1, 2021July 31, 2024PECHOUS, ROGER Dreporter.nih.gov
Colorado APS Clinical CenterNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,144,687May 1, 2023April 30, 2029MOSS, MARCreporter.nih.gov
Phenotyping ARDS, Pneumonia, and Sepsis over time to elucidate shared and distinct trajectories ofillness and recoveryNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,144,421May 1, 2023April 30, 2029MEYER, NUALA JENNINGSreporter.nih.gov
Great Lakes Clinical Center of the Acute Respiratory Distress Syndrome, Pneumonia and Sepsis (APS) ConsortiumNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,140,945May 1, 2023April 30, 2029HYZY, ROBERT Creporter.nih.gov
The Intermountain West-Atlantic Center (InterACT) for the APS Phenotyping ConsortiumNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,133,343May 1, 2023April 30, 2029BROWN, SAMUEL MORRISreporter.nih.gov
The vital role of T403 phosphorylation of STAT2 in post-viral bacterial pneumoniaNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,127,000March 20, 2024February 28, 2029WANG, YUXINreporter.nih.gov
PRC2 independent role of Ezh2 in regulation of basal cell dynamics post-influenza virus infectionNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,126,282September 1, 2024May 31, 2029YAO, CHANGFUreporter.nih.gov
Protecting Endogenous Recovery from the "Infectious Insult" in Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,121,721September 20, 2024August 31, 2029FILOUS, ANGELA Rreporter.nih.gov
Atlas of efflux and permeation determinants to advance antibacterial therapeutic discoveryNIHNational Institute of Allergy and Infectious Diseases2025$1,120,070July 21, 2025June 30, 2030ZGURSKAYA, HELEN Ireporter.nih.gov
Molecular Phenotyping of ARDS, Pneumonia, and Sepsis using Latent Class Analysis and Metagenomic SequencingNIHNational Heart, Lung, and Blood Institute2023 to 2025$1,118,088May 1, 2023April 30, 2029CALFEE, CAROLYNreporter.nih.gov
Mechanisms of host protection against pathogen-associated proteases in acute lung injuryNIHNational Heart, Lung, and Blood Institute2023 to 2024$1,115,035September 1, 2016August 31, 2025LEE, JANET SOJUNGreporter.nih.gov
The role of circadian clock proteins in innate and adaptive immunityNIHNational Institute of General Medical Sciences2023 to 2025$1,096,430September 26, 2022July 31, 2026ROSENGART, MATTHEW RANDALLreporter.nih.gov
Armed nanobodies as anti-infectives and anti-tumor agentsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,085,800July 19, 2024May 31, 2029WU, HAOreporter.nih.gov
Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector BiologyNIHNational Institute of Allergy and Infectious Diseases2025$1,082,429December 19, 2024November 30, 2029CHAN, CLIBURN Creporter.nih.gov
Lung-derived complement in pneumoniaNIHNational Heart, Lung, and Blood Institute2023 to 2024$1,073,597May 19, 2023April 30, 2028KULKARNI, HRISHIKESH SATISHreporter.nih.gov
Inducible HMGB1 antagonist for viral-induced acute lung injury.NIHNational Heart, Lung, and Blood Institute2023 to 2024$1,068,694August 16, 2023July 31, 2025BLANCO, JORGE Creporter.nih.gov
CD4+ T cell Immunity in the Respiratory TractNIHNational Heart, Lung, and Blood Institute2025$1,063,324June 5, 2025May 31, 2032KOLLS, JAY Kreporter.nih.gov
Biomimetic nanoparticles to enhance the breadth of influenza vaccinesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,062,524August 7, 2020July 31, 2025WU, MEI Xreporter.nih.gov
The role of Nrf2 in T cell function and influenzaNIHNational Institute of Environmental Health Sciences2024 to 2025$1,053,331July 6, 2024April 30, 2029ROCKWELL, CHERYL ELIZABETHreporter.nih.gov
IND-enabling studies of an intranasal, single-replication M2SR influenza vaccineNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,048,815August 1, 2015June 30, 2026BILSEL, PAMUKreporter.nih.gov
The BLAAST Trial: Bangladesh Lung Auscultation AI for Antibiotic Stewardship Randomized Controlled TrialNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2024 to 2025$1,038,588September 1, 2024May 31, 2029MCCOLLUM, ERIC DOUGLASSreporter.nih.gov
The Role of TRIM6 and Ubiquitin in Influenza Virus-Induced PathologyNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$1,032,987May 13, 2021April 30, 2027RAJSBAUM, RICARDOreporter.nih.gov
Age related loss of immune resilience during response to severe respiratory viral infectionsNIHNational Institute on Aging2024 to 2025$1,028,435July 1, 2024April 30, 2029SEGAL, LEOPOLDO NICOLASreporter.nih.gov
Establishing and Implementing Pneumonia Diagnosis in ED Older Adults: A Mixed Methods ApproachNIHNational Institute on Aging2022 to 2025$1,018,845September 15, 2022June 30, 2027BUCK, KATHERINE HUNOLDreporter.nih.gov
Development of IN-003PI as passive immunization against human metapneumovirus infectionNIHNational Institute of Allergy and Infectious Diseases2025$1,013,468September 1, 2025July 31, 2028HUTCHINS, JEFF Treporter.nih.gov
Dissecting the viral and host constraints that govern influenza virus antigenic evolutionNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$1,013,305December 1, 2023October 31, 2028BROOKE, CHRISTOPHER BYRONreporter.nih.gov
IND-enabling development for IN-005, an inhaled muco-trapping mAb therapy against Influenza ANIHNational Institute of Allergy and Infectious Diseases2025$1,013,003August 1, 2025July 31, 2028HUTCHINS, JEFF Treporter.nih.gov
AT191: An inhaled & precision RNA therapeutic with pan-variant SARS-CoV-2 efficacyNIHNational Institute of Allergy and Infectious Diseases2025$1,004,473September 10, 2025August 31, 2028WEINBERGER, ARIELreporter.nih.gov
A capsule-based bioconjugate vaccine to prevent Klebsiella pneumoniae infectionsNIHNational Institute of Allergy and Infectious Diseases2025$1,000,000January 1, 2022August 31, 2028HARDING, CHRISTIANreporter.nih.gov
Development of a shelf-stable universal mucosal HA-vaccine for the prevention of influenzaNIHNational Institute of Allergy and Infectious Diseases2025$1,000,000July 3, 2023December 31, 2026DAVENPORT, GREGORYreporter.nih.gov
Causal Inference in Infectious Disease Prevention StudiesNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$982,276December 1, 2009May 31, 2026HUDGENS, MICHAEL Greporter.nih.gov
Innate Control of Adaptive Immunity to SARS-CoV-2NIHNational Institute of Allergy and Infectious Diseases2021 to 2025$968,772June 1, 2021May 31, 2026GOLDMAN-ISRAELOW, BENJAMINreporter.nih.gov
Protection of at-risk low birth weight infants against influenza via maternal antibodyNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$942,300June 1, 2021May 31, 2026KACHIKIS, ALISAreporter.nih.gov
Role of ERK1/2 signaling in SARS-CoV-2 -induced dysregulated immunity and lung pathology.NIHNational Heart, Lung, and Blood Institute2024 to 2025$930,578September 6, 2024June 30, 2029CHANNAPPANAVAR, RUDRAGOUDAreporter.nih.gov
Dissecting the host-plasmid interplay to unravel the spread of ESBL-producing K. pneumoniaeNIHNational Institute of Allergy and Infectious Diseases2025$874,998August 13, 2025June 30, 2030KREISWIRTH, BARRY NEALreporter.nih.gov
Infant Protection from Influenza through Maternal Influenza ImmunizationNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$874,965June 1, 2021May 31, 2027RICK, ANNE-MARIEreporter.nih.gov
Pediatric Recovery After Sepsis Treatment in the Pediatric Intensive Care UnitNIHNational Institute of General Medical Sciences2022 to 2025$859,700September 1, 2022August 31, 2026PERRY-EADDY, MALLORY Areporter.nih.gov
The basis of Influenza A virus strain-dependent reassortment potentialNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$858,639February 14, 2024January 31, 2029DIAZ, SAMUEL Lreporter.nih.gov
Defining the Role of ANKEF1 in Ciliary Function and Host Defense Against Influenza Virus InfectionNIHNational Institute of Allergy and Infectious Diseases2025$856,791September 12, 2025August 31, 2026MIORIN, LISAreporter.nih.gov
Predisposition for Lung Injury in Sepsis SurvivalNIHNational Heart, Lung, and Blood Institute2021 to 2025$847,800May 1, 2021April 30, 2026DENSTAEDT, SCOTT JOHNreporter.nih.gov
Explore a key nucleotide synthesis enzyme to develop a broad-spectrum antiviral therapy.NIHNational Institute of Allergy and Infectious Diseases2025$831,235August 21, 2025July 31, 2030FENG, PINGHUIreporter.nih.gov
The NF-kappaB modulator PDLIM2 as an intrinsic checkpoint of alveolar macrophages critical for lung innate immunity, inflammation and diseasesNIHNational Heart, Lung, and Blood Institute2025$829,998April 1, 2025January 31, 2029QU, ZHAOXIAreporter.nih.gov
Epitope and mechanistic correlates of broadly protective human antibodies for pneumococcal infectionNIHNational Institute of Allergy and Infectious Diseases2023 to 2024$828,509November 1, 2022November 30, 2023MOUSA, JARRODreporter.nih.gov
Targeting Angiopoietin-like 4 (ANGPTL4) in Severe Community Acquired PneumoniaNIHNational Heart, Lung, and Blood Institute2025$827,909April 4, 2025January 31, 2029BHATRAJU, PAVAN KUMARreporter.nih.gov
Beta-Lactamase Inhibitors Sensitize Multidrug-Resistant Gram-negative Pathogens to Innate Immune ClearanceNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$820,829April 1, 2020March 31, 2026ULLOA, ERLINDA ROSEreporter.nih.gov
Lung vascular ILC3 subpopulation in anti-bacteria immunity and vasculature regenerationNIHNational Heart, Lung, and Blood Institute2025$814,387August 1, 2025April 30, 2029HUANG, YUEFENGreporter.nih.gov
Assessing functional immunity to influenza infection by quantifying BCR binding aviditiesNIHNational Institute of Allergy and Infectious Diseases2025$811,009November 13, 2024October 31, 2029GEORGE, STEVEN CARLreporter.nih.gov
Mechanisms of regulatory T-cell mediated endothelial repair following viral pneumonia in aged hostsNIHNational Heart, Lung, and Blood Institute2021 to 2025$805,882September 20, 2021August 31, 2026MORALES-NEBREDA, LUISAreporter.nih.gov
The oxidation of heme-carrying proteins in the pathophysiology of pneumococcal diseaseNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$805,442November 20, 2023October 31, 2028VIDAL, JORGE EUGENIOreporter.nih.gov
Pulmonary gamma-delta T cells in lung infectionNIHNational Heart, Lung, and Blood Institute2021 to 2025$804,060June 15, 2021May 31, 2027WRIGHT, SHELTON WILEYreporter.nih.gov
Optimizing Medications and Lung Health in People with HIV through Pharmacist-led Proactive E-Consults (OPTIMIZE Lung-HIV)NIHNational Heart, Lung, and Blood Institute2025$803,801August 15, 2025May 31, 2030CROTHERS, KRISTINA ANNEreporter.nih.gov
Detrimental Effects of B-Cell-Th17 Axis in Antiviral Immunity in Smokers.NIHNational Heart, Lung, and Blood Institute2025$799,998September 1, 2025May 31, 2030KHERADMAND, FARRAHreporter.nih.gov
Protecting Patients with Glomerular Disease from Vaccine-Preventable InfectionsNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$795,246February 15, 2022January 31, 2027GLENN, DOREYreporter.nih.gov
The interplay of maternal antibody and newborn vaccine responsesNIHNational Institute of Allergy and Infectious Diseases2025$793,102April 17, 2025March 31, 2030ALEXANDER-MILLER, MARTHA ANNreporter.nih.gov
Identifying Novel Roles and the Therapeutic Potential of the Thrombin Receptor Protease Activated Receptor-1 (PAR1) in Lung Lymphatic Function and Acute Respiratory Distress SyndromeNIHNational Heart, Lung, and Blood Institute2025$791,503September 15, 2025June 30, 2029REED, HASINA OUTTZreporter.nih.gov
iPSC-derived macrophages as a model to study the genetic basis of inter-individual variation in immune responses to pathogensNIHNational Institute of Allergy and Infectious Diseases2025$785,511January 24, 2025December 31, 2029BARREIRO, LUIS BRUNOreporter.nih.gov
Elucidating the genotypic determinants and phenotypic effects of polymyxin resistance in Klebsiella pneumoniae utilizing CRISPR-Cas9NIHNational Institute of Allergy and Infectious Diseases2021 to 2024$769,824July 1, 2020June 30, 2026MCCONVILLE, THOMAS HOWEreporter.nih.gov
Elucidating Olfactory Epithelial Anti-Viral Responses in Persistent Post-Viral Olfactory DysfunctionNIHNational Institute on Deafness and Other Communication Disorders2022 to 2025$767,492February 1, 2022January 31, 2027YAN, CAROL Hreporter.nih.gov
Migration and resolution, lung microenvironment and mechanisms: examining the diverse responses of neutrophils during S. pneumoniae pneumonia and acute lung injuryNIHNational Heart, Lung, and Blood Institute2025$759,983May 15, 2025February 28, 2029DOERSCHUK, CLAIRE Mreporter.nih.gov
Molecular Basis for the TREX-2 mRNA Nuclear Export PathwayNIHNational Institute of General Medical Sciences2025$758,594September 1, 2025August 31, 2027FONTOURA, BEATRIZ MAreporter.nih.gov
Rational design of a unique vaccine for emerging pandemic coronavirusesNIHNational Institute of Allergy and Infectious Diseases2025$755,225December 6, 2024November 30, 2029QIAO, LIANGreporter.nih.gov
Pathogenic mechanisms of chronic lung sequelae following respiratory viral infectionNIHNational Heart, Lung, and Blood Institute2025$754,729August 10, 2025May 31, 2029ZHANG, LIANGHUIreporter.nih.gov
Identifying mechanisms by which metformin regulates T cell responses in obesityNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$753,296December 20, 2024November 30, 2029MACIVER, NANCIEreporter.nih.gov
Putting Implementation into context to advance the management of mechanically ventilated patients.NIHNational Heart, Lung, and Blood Institute2025$748,970August 15, 2025May 31, 2029KERLIN, MEETA PRASADreporter.nih.gov
Refining our understanding of antimicrobial peptide mediated disruption of the Klebsiella pneumoniae capsuleNIHNational Institute of Allergy and Infectious Diseases2023 to 2025$747,000August 24, 2021March 31, 2027FLEEMAN, RENEEreporter.nih.gov
Mechanisms of GM-CSF-mediated metabolic regulation of monocyte function for control of pulmonary infectionNIHNational Heart, Lung, and Blood Institute2023 to 2025$747,000August 5, 2023July 31, 2026LIU, XINreporter.nih.gov
Lung epithelial cell reprogramming by CD4 T cellsNIHNational Heart, Lung, and Blood Institute2023 to 2025$746,997April 1, 2023March 31, 2026SHENOY, ANUKUL Treporter.nih.gov
Exploring the role of T cells in protection from respiratory virus transmissionNIHNational Institute of Allergy and Infectious Diseases2025$744,977February 1, 2025January 31, 2030KOHLMEIER, JACOB Ereporter.nih.gov
Oseltamivir Use and Risk of Serious Neuropsychiatric Adverse Events in ChildrenNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$740,087March 1, 2022February 28, 2026ANTOON, JAMES Wreporter.nih.gov
Mechanistic bases of strain-specific virus-host interactionsNIHNational Institute of General Medical Sciences2024 to 2025$729,993February 1, 2024January 31, 2029CHO, JAE HYUNreporter.nih.gov
Impact of Diet Induced Obesity on Acute Lung InjuryNIHNational Heart, Lung, and Blood Institute2022 to 2025$725,760January 15, 2022January 17, 2025PLATAKI, MARIAreporter.nih.gov
Monocyte-derived galectin-1 promotes tissue-resident memory T cell responseNIHNational Institute of Allergy and Infectious Diseases2025$722,958November 22, 2024October 31, 2029KIM, MINSOOreporter.nih.gov
Pulmonary neuroimmune determinants of immunoglobulin production against pneumoniaNIHNational Heart, Lung, and Blood Institute2025$718,661August 1, 2025April 30, 2030JENDZJOWSKY, NICHOLASreporter.nih.gov
Mentoring in transmission of influenza and strategies for preventionNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$714,408February 3, 2020October 31, 2025GRIJALVA, CARLOS Greporter.nih.gov
REINVIGORATE: Repeated Enhanced INfluenza Vaccines In Geriatrics of a Randomised trial for Antibody and T cell EffectsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$711,626April 11, 2024March 31, 2029DOAK, SOPHIE ALESSANDRA VALKENBURGreporter.nih.gov
Glycan-Mediated Impacts on the Mucus Barrier Towards Respiratory VirusesNIHNational Heart, Lung, and Blood Institute2025$711,144September 1, 2025June 30, 2029SCULL, MARGARET ADELEreporter.nih.gov
Immunity in the Nose to inFLUENza: Correlates of Efficacy (INFLUENCE)NIHNational Institute of Allergy and Infectious Diseases2023 to 2024$701,638May 4, 2023April 30, 2025THWAITES, RYANreporter.nih.gov
Community - based behavioral intervention to increase COVID - 19 and influenza vaccination for African American/ Black and Latino persons: An optimization randomized controlled trialNIHNational Institute on Minority Health and Health Disparities2024$688,573September 22, 2024April 1, 2025GWADZ, MARYAreporter.nih.gov
2/2 WIN Ratio Analysis to Determine a Strategy of Non-Invasive SUpport for Respiratory Failure in the EmeRgency Department (WINDSURFER)NIHNational Heart, Lung, and Blood Institute2025$688,047September 1, 2025August 31, 2031DURKALSKI, VALERIE Lreporter.nih.gov
Nosocomial pneumonia impairs the cerebrovasculatureNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$684,527May 16, 2024May 2, 2025NELSON, AMY Rreporter.nih.gov
Targeting Estrogenic pathways in Tregs to promote ARDS resolution - 5R01HL163881NIHNational Heart, Lung, and Blood Institute2025$684,280August 15, 2025May 31, 2027D'ALESSIO, FRANCO RAFAELreporter.nih.gov
Extending neutrophil survival in neutropenia-related pneumoniaNIHNational Heart, Lung, and Blood Institute2025$676,748July 1, 2025March 31, 2029LUO, HONGBO Rreporter.nih.gov
Spatial and Temporal Adjuvant Delivery for Skin mRNA VaccinationNIHNational Institute of Allergy and Infectious Diseases2025$676,666September 3, 2025August 31, 2030WU, MEI Xreporter.nih.gov
Role of respiratory viral infections and inflammation in promoting metastatic outgrowth in the lungNIHNational Cancer Institute2025$672,011March 1, 2025February 28, 2030DEGREGORI, JAMES Vreporter.nih.gov
The effect of household air pollution on lung function growth in infants with pneumonia in sub-Saharan Africa.NIHNational Institute of Environmental Health Sciences2021 to 2024$670,862March 14, 2024February 28, 2025MOSCHOVIS, PETER Preporter.nih.gov
Characterization and optimization of single dose, thermostable and durable vaccine platform towards increased clinical acceptanceNIHNational Institute of Allergy and Infectious Diseases2024$668,569August 23, 2024June 30, 2029ZABALETA, NEREAreporter.nih.gov
Hospital adaptation and resiliency for infected and uninfected patients during respiratory viral surge events: from seasonal influenza to COVID-19NIHNational Heart, Lung, and Blood Institute2022 to 2025$664,475December 15, 2021November 30, 2026ANESI, GEORGE Lreporter.nih.gov
Task A04: Mouse Models for Evaluation of Therapeutics against Human Seasonal Influenza and Avian Influenza Strains with Pandemic PotentialNIHNational Institute of Allergy and Infectious Diseases2024$663,068September 24, 2024September 23, 2025COOK, MIKAYLAreporter.nih.gov
The role of HMGB1 in the lung response to bacterial injuryNIHNational Heart, Lung, and Blood Institute2025$656,988August 1, 2025April 30, 2030MESSER, JEANNETTE SOPHIAreporter.nih.gov
Full Spectrum Cell Sorter with Imaging Enhancement for Boston University Flow Cytometry Core FacilityNIHOffice of the Director, National Institutes of Health2025$656,148April 15, 2025April 14, 2026BELKINA, ANNAreporter.nih.gov
Intrapulmonary itaconate as a host-protective metabolite during ER Stress and Klebsiella pneumoniae infectionNIHNational Heart, Lung, and Blood Institute2022 to 2025$642,944April 1, 2022March 31, 2027SUBER, TOMEKA Lreporter.nih.gov
Impaired Pneumococcal Antibody Function and Exacerbations of Chronic Obstructive Pulmonary DiseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$642,128January 1, 2022December 31, 2026LAFON, DAVID CARDYreporter.nih.gov
Mechanisms of CD8 TRM-mediated protection against respiratory virus transmissionNIHNational Institute of Allergy and Infectious Diseases2024$640,735July 26, 2024June 30, 2025KOHLMEIER, JACOB Ereporter.nih.gov
CD38, T cells and post viral lung sequelae during agingNIHNational Institute on Aging2025$639,740December 15, 2024November 30, 2029SUN, JIEreporter.nih.gov
Implementation research to improve the uptake of influenza vaccination in CKDNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$627,765August 4, 2021March 10, 2025ISHIGAMI, JUNICHIreporter.nih.gov
Gene regulatory network of memory B cell and long-lived plasma cell differentiationNIHNational Institute of Allergy and Infectious Diseases2025$625,348July 3, 2025June 30, 2030ROY, KOUSHIKreporter.nih.gov
Developing mRNAdesigner tool package for optimization of mRNA sequenceNIHNational Institute of General Medical Sciences2024 to 2025$624,000September 30, 2024June 30, 2028ZHOU, XIAOBOreporter.nih.gov
Targeted genetic engineering of B cells to induce protective antibody responses to pathogensNIHNational Institute of Allergy and Infectious Diseases2025$618,943July 5, 2022June 30, 2027ADAIR, JENNIFER EILEENreporter.nih.gov
Eosinophils as Effectors of Antibacterial Immunity in the LungsNIHNational Heart, Lung, and Blood Institute2024$615,455September 1, 2024June 30, 2028SAMARASINGHE, AMALIreporter.nih.gov
A redox-sensitive switch in the macrophage nucleus regulates acute phaseinflammatory injuryNIHNational Heart, Lung, and Blood Institute2025$613,814June 1, 2022May 31, 2027BONINI, MARCELO G.reporter.nih.gov
Eosinophils as Effectors of Antibacterial Immunity in the LungsNIHNational Heart, Lung, and Blood Institute2025$613,501September 1, 2024June 30, 2028SAMARASINGHE, AMALI Ereporter.nih.gov
The Role of Ariadne RBR E3 ubiquitin protein ligase 2 (ARIH2) in influenza A virus replication and pathogenesis in the airway epithelial cellsNIHNational Institute of Allergy and Infectious Diseases2025$605,778July 7, 2025June 30, 2030MEBRATU, YOHANNES AFEWORKreporter.nih.gov
Novel Hybrid Computational Models to Disentangle Complex Immune ResponsesNIHNational Institute of General Medical Sciences2023 to 2025$600,000September 26, 2023August 31, 2027HERNANDEZ VARGAS, ESTEBAN ABELARDOreporter.nih.gov
Mechanisms of Klebsiella pneumoniae gastrointestinal colonizationNIHNational Institute of Allergy and Infectious Diseases2025$599,768June 14, 2023May 31, 2029ZAFAR, MUHAMMAD AMMARreporter.nih.gov
A more durable and universal adjuvanted influenza vaccine through synthetic biologyNIHNational Institute of Allergy and Infectious Diseases2025$599,526June 1, 2025May 31, 2027KEMPINSKI, CHASEreporter.nih.gov
MRNA VACCINE DEVELOPMENTNIHNational Institute of Allergy and Infectious Diseases2024$594,566September 1, 2024August 31, 2026ANDRIANOVA, KATERINAreporter.nih.gov
Mechanisms by which NS1 and NEP govern the influenza lifecycleNIHNational Institute of Allergy and Infectious Diseases2025$587,885September 18, 2025August 31, 2030PETIT, CHADreporter.nih.gov
Host factors influencing early clearance of Streptococcus pneumoniae from the middle ear following invasion from the nasopharynxNIHNational Institute on Deafness and Other Communication Disorders2022 to 2024$583,125February 1, 2022July 31, 2025CLARK, SARAH Ereporter.nih.gov
Individualizing Steroid Use in Pneumonia (Supplement)NIHNational Heart, Lung, and Blood Institute2023 to 2025$582,229June 1, 2023July 31, 2026ODEYEMI, YEWANDEreporter.nih.gov
Use of probiotics to modulate antimicrobial peptide signaling in the neonatal innate immune response to influenza virusNIHNational Institute of Allergy and Infectious Diseases2025$554,786September 17, 2025August 31, 2027CAREY, ALISON Jreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Icahn School of Medicine at Mount SinaiNew York, NY15$158 million0$0
The Emmes Company, LLCRockville, MD1$150.3 million0$0
Duke UniversityDurham, NC14$140.5 million0$0
ST. Jude Children's Research HospitalMemphis, TN12$130.9 million0$0
University of Georgia Research Foundation IncAthens, GA8$84.7 million0$0
University of PennsylvaniaPhiladelphia, PA21$79 million0$0
Emory UniversityAtlanta, GA26$75.6 million0$0
Vanderbilt University Medical CenterNashville, TN9$72 million0$0
Johns Hopkins UniversityBaltimore, MD20$49.3 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH4$39.1 million0$0
University of ChicagoChicago, IL12$34.8 million0$0
University of Alabama at BirminghamBirmingham, AL19$30.1 million0$0
University of WashingtonSeattle, WA14$29.8 million0$0
University of Maryland BaltimoreBaltimore, MD7$27.5 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA20$24.3 million0$0
New York University School of MedicineNew York, NY7$24.3 million0$0
Digital Infuzion, Inc.Rockville, MD2$22.8 million0$0
Columbia University Health SciencesNew York, NY14$21.8 million0$0
Saint Louis UniversitySaint Louis, MO1$21.2 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC13$19.7 million0$0
Boston University Medical CampusBoston, MA14$18.8 million0$0
Ohio State UniversityColumbus, OH14$18.1 million0$0
University of California-IrvineIrvine, CA6$17.9 million0$0
Boston Children's HospitalBoston, MA8$17.1 million0$0
La Jolla Institute for ImmunologyLa Jolla, CA3$15.9 million0$0
University of Colorado DenverAurora, CO10$15.7 million0$0
Washington UniversitySaint Louis, MO12$15.3 million0$0
Cedars-Sinai Medical CenterLos Angeles, CA7$14.8 million0$0
University of Michigan at Ann ArborAnn Arbor, MI14$14.2 million0$0
University of Wisconsin-MadisonMadison, WI7$14.2 million0$0
Kaiser Foundation Research InstituteOakland, CA1$14.2 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA13$14.2 million0$0
Brigham and Women's HospitalBoston, MA7$13.9 million0$0
University of Missouri-ColumbiaColumbia, MO8$13.8 million0$0
Northwestern University at ChicagoChicago, IL17$12.6 million0$0
University of California, San DiegoLa Jolla, CA11$12.4 million0$0
University of IowaIowa City, IA10$12.2 million0$0
Rockefeller UniversityNew York, NY3$11.9 million0$0
Massachusetts General HospitalBoston, MA11$11.7 million0$0
Jackson LaboratoryBar Harbor, ME2$11.7 million0$0
University of MontanaMissoula, MT1$11.6 million0$0
Versatope Therapeutics, Inc.Lowell, MA1$10.9 million0$0
Regents of the University of IdahoMoscow, ID2$10.3 million0$0
Stanford UniversityStanford, CA8$10.2 million0$0
University of VirginiaCharlottesville, VA6$9.9 million0$0
Scripps Research Institute, theLa Jolla, CA6$9.9 million0$0
University of California, San FranciscoSan Francisco, CA5$9 million0$0
SUNY at BuffaloAmherst, NY6$8.7 million0$0
Inhalon Biopharma, Inc.Morrisville, NC5$8.7 million0$0
Yale UniversityNew Haven, CT9$8.4 million0$0
Ut Southwestern Medical CenterDallas, TX5$8.1 million0$0
University of Illinois at ChicagoChicago, IL5$8 million0$0
Tulane University of LouisianaNew Orleans, LA6$7.5 million0$0
Georgia State UniversityAtlanta, GA4$7.5 million0$0
University of Maryland, College ParkCollege Park, MD6$7.4 million0$0
University of Illinois at Urbana-ChampaignUrbana, IL6$7.4 million0$0
University of Miami School of MedicineCoral Gables, FL3$7.4 million0$0
University of South AlabamaMobile, AL7$7.2 million0$0
University of Maryland Baltimore CountyBaltimore, MD1$7.1 million0$0
Wake Forest University Health SciencesWinston-Salem, NC7$7.1 million0$0
Washington State UniversityPullman, WA1$6.7 million0$0
Fred Hutchinson Cancer CenterSeattle, WA3$6.7 million0$0
TSRL, Inc.Ann Arbor, MI3$6.5 million0$0
Mayo Clinic RochesterRochester, MN5$6.5 million0$0
Lurie Children's Hospital of ChicagoChicago, IL4$6.4 million0$0
University of California-San Diego Scripps Inst of OceanographyLa Jolla, CA1$6.4 million0$0
University of UtahSalt Lake City, UT5$6.3 million0$0
Orlance, Inc.Seattle, WA3$6.3 million0$0
Tufts University BostonBoston, MA4$6.2 million0$0
Nubad, LLCGreer, SC2$6.2 million0$0
Novobiotic Pharmaceuticals, LLCCambridge, MA1$6.2 million0$0
Inimmune CorporationMissoula, MT1$5.9 million0$0
Northeastern UniversityBoston, MA2$5.9 million0$0
International Aids Vaccine InitiativeNew York, NY1$5.6 million0$0
University of RochesterRochester, NY6$5.5 million0$0
Greffex, Inc.Aurora, CO1$5.5 million0$0
Weill Medical Coll of Cornell UnivNew York, NY4$5.4 million0$0
Curza INCSalt Lake City, UT2$4.9 million0$0
Dana-Farber Cancer InstBoston, MA1$4.8 million0$0
University of MinnesotaMinneapolis, MN3$4.7 million0$0
University of Southern CaliforniaLos Angeles, CA3$4.6 million0$0
The University of Central Florida Board of TrusteesOrlando, FL3$4.5 million0$0
University of TX MD Anderson Can CTRHouston, TX2$4.5 million0$0
Research Inst of Fox Chase Can CTRPhiladelphia, PA1$4.2 million0$0
Massachusetts Institute of TechnologyCambridge, MA3$4.2 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA2$4.1 million0$0
University of Texas Med BR GalvestonGalveston, TX3$4 million0$0
Iowa State UniversityAmes, IA2$3.9 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH3$3.9 million0$0
Louisiana State UniversityBaton Rouge, LA4$3.8 million0$0
New York Blood CenterNew York, NY1$3.7 million0$0
Florida State UniversityTallahassee, FL3$3.7 million0$0
Vaxnewmo, LLCSaint Louis, MO2$3.6 million0$0
Georgia Tech Research CorporationAtlanta, GA4$3.5 million0$0
University of Tennessee Health Sci CTRMemphis, TN2$3.5 million0$0
University of FloridaGainesville, FL2$3.4 million0$0
Chicago Biosolutions, Inc.Chicago, IL1$3.3 million0$0
Rensselaer Polytechnic InstituteTroy, NY1$3.3 million0$0
Brown UniversityProvidence, RI2$3.2 million0$0
University of CincinnatiCincinnati, OH5$3.2 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025547$442,861,0060$0
2024597$470,760,7710$0
2023444$430,271,8670$0
2022288$347,740,1320$0
2021190$335,837,7260$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 9 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 4 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 2 awards here
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)PA-24-176NIHMay 7, 2027Not listedNotice number printed on 1 award here
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)RFA-AI-27-002NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 450 awards here
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)RFA-AI-27-005NIH93.855November 10, 2026Not listedSame assistance listing 93.855 as 450 awards here
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)PAR-25-370NIH93.855November 16, 2026$50,000Same assistance listing 93.855 as 450 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 450 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.855November 18, 2026Not listedSame assistance listing 93.855 as 450 awards here
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)PAR-25-379NIH93.855January 7, 2027Not listedSame assistance listing 93.855 as 450 awards here
HIV/AIDS Clinical Trials Network Leadership and Operations CentersRFA-AI-28-001NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 450 awards here
HIV/AIDS Clinical Trials Network Laboratory CentersRFA-AI-28-002NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 450 awards here
HIV/AIDS Clinical Trials Network Statistical and Data Management CentersRFA-AI-28-003NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 450 awards here
HIV/AIDS Clinical Trials Network Clinical Trials UnitsRFA-AI-28-004NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 450 awards here
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious DiseasesRFA-AI-28-014NIH93.855January 22, 2027Not listedSame assistance listing 93.855 as 450 awards here
Immune Tolerance Network (UM1 Clinical Trial Required)RFA-AI-28-005NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 450 awards here
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)RFA-AI-28-012NIH93.855January 29, 2027Not listedSame assistance listing 93.855 as 450 awards here
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)RFA-AI-28-024NIH93.855February 11, 2027Not listedSame assistance listing 93.855 as 450 awards here
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)RFA-LM-28-001NIH93.855February 11, 2027$775,000Same assistance listing 93.855 as 450 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.855April 5, 2027Not listedSame assistance listing 93.855 as 450 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.