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Data / Research funding / Peripheral Neuropathy

Peripheral Neuropathy: 783 NIH awards ($844.9M) to 225 organizations

783 NIH awards ($844.9M) in the NIH spending category Peripheral Neuropathy, to 225 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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Awards

The 500 largest of 783 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
EPPIC-Net Pain Research - Application for Clinical Trial and Related Activities (OT2)NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$19,316,294January 1, 2021July 31, 2026FAVA, MAURIZIOreporter.nih.gov
Site-Directed RNA Editing of Nav1.7 as a Novel AnalgesicNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$11,194,636September 23, 2021August 31, 2027ROSENTHAL, JOSHUA J.C.reporter.nih.gov
Human Nociceptor and Spinal Cord Molecular Signature CenterNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$9,264,871September 19, 2022August 31, 2027PRICE, THEODORE J.reporter.nih.gov
Sensory Phenotyping to Enhance Neuropathic Pain Drug DevelopmentNIHNational Institute of Neurological Disorders and Stroke2025$7,081,684September 21, 2023August 31, 2028FREEMAN, ROYreporter.nih.gov
Unravelling Mechanisms and Novel Therapeutic Targets for Peripheral Neuropathy and Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$6,767,963December 15, 2017November 30, 2025WOOLF, CLIFFORD Jreporter.nih.gov
Mechanisms of Action of Peripheral Nerve Stimulation for the Treatment of Chronic Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2023$6,522,833September 20, 2023August 31, 2026HAH, JENNIFERreporter.nih.gov
Remote Monitoring of Management of Chemotherapy induced Peripheral NeuropathyNIHNational Cancer Institute2021 to 2025$6,132,390May 6, 2021April 30, 2027KOLB, NOAH ALLANreporter.nih.gov
Development and Optimization of MNK Inhibitors for the Treatment of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$5,575,218September 1, 2021August 31, 2025SAHN, JAMES JEFFREYreporter.nih.gov
Understanding neural control of the ocular surfaceNIHNational Eye Institute2022 to 2025$5,561,710September 30, 2022August 31, 2027JENKINS, MICHAEL W.reporter.nih.gov
Development of a Potent and Selective Nav1.8 inhibitor for the Treatment of Acute and Chronic Pain with the Goal of Reducing Opioid Use and Preventing Opioid Use DisordersNIHNational Institute on Drug Abuse2023$5,341,667May 15, 2023April 30, 2025HUNTER, JOHN CURETONreporter.nih.gov
Optimizing the use of ketamine to reduce chronic postsurgical painNIHNational Cancer Institute2021 to 2024$5,247,593September 17, 2021August 31, 2025WANG, JINGreporter.nih.gov
High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$5,225,127January 1, 2025April 30, 2025MCLAUGHLIN, BRYAN Lreporter.nih.gov
Development of a Soluble Epoxide Hydrolase Inhibitor to Spare or Replace Opioid AnalgesicsNIHNational Institute on Drug Abuse2024 to 2025$4,623,799September 30, 2019December 31, 2026CORTES-PUCH, IRENEreporter.nih.gov
Underpinnings of corneal innervation: anatomical, molecular, and functional studies of corneal sensory afferents in physiologic and pathologic statesNIHNational Eye Institute2022 to 2025$4,440,467September 30, 2022August 31, 2027ROMPOLAS, PANTELEIMONreporter.nih.gov
Genetic Susceptibility and Biomarkers of Platinum-related ToxicitiesNIHNational Cancer Institute2021 to 2025$4,370,186September 25, 2012June 30, 2027TRAVIS, LOIS B.reporter.nih.gov
The biophysics of skin-neuron sensory tactile organs and their sensitivity to mechanical and chemical stressNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,231,127December 15, 2017September 30, 2026GOODMAN, MIRIAM Breporter.nih.gov
STRUCTURAL VARIATION IN NEUROLOGICAL DISEASENIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,141,654December 15, 2017November 30, 2026LUPSKI, JAMES R.reporter.nih.gov
Pain Mechanisms in Fabry DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$4,085,512May 15, 2019March 31, 2026STUCKY, CHERYL LOUISEreporter.nih.gov
A fully humanized functional genomic screen to identify and validate pain therapeutic targetsNIHNational Institute of Neurological Disorders and Stroke2025$4,039,366September 1, 2025August 31, 2028PRICE, THEODORE J.reporter.nih.gov
Differentiation of Clinical Phenotypes of Inflammatory and Neuropathic Ocular Pain Conditions with Morphologic Measures and Functional Brain ImagingNIHNational Eye Institute2022 to 2025$3,722,281September 30, 2022August 31, 2027MOULTON, ERIC ALANreporter.nih.gov
Accelerate Clinical Trials in CMT (ACTCMT) StudyNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$3,658,507May 1, 2019February 28, 2026HERRMANN, DAVID Nreporter.nih.gov
Transspinal Magnetic Stimulation for the Treatment of Neuropathic PainNIHNational Institute of Biomedical Imaging and Bioengineering2024$3,565,780September 18, 2024August 31, 2027BONMASSAR, GIORGIOreporter.nih.gov
Development and validation of a porcine model of spinal cord injury-induced neuropathic painNIHNational Institute of Neurological Disorders and Stroke2023$3,560,956September 21, 2023August 31, 2026FLOYD, CANDACE L.reporter.nih.gov
Targeting p38/JNK MAPK to ameliorate cisplatin-induced adverse sequelae on the nervous systemNIHNational Cancer Institute2021 to 2025$3,433,365July 1, 2021June 30, 2027BOTA, DANIELA ANNENELIEreporter.nih.gov
Uncovering early signals of hereditary TTR amyloidosis in minority populations at high genetic riskNIHNational Heart, Lung, and Blood Institute2021 to 2025$3,411,450April 1, 2021March 31, 2027KONTOROVICH, AMY R.reporter.nih.gov
Discovery of PSD95 protein-protein interaction inhibitors as novel non-opioid analgesicsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$3,311,688March 1, 2021February 28, 2026FLORIO, STEPHANIE Kreporter.nih.gov
Biomarkers of Tissue Tolerance and Behavior in a Rat ModelNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$3,262,661July 1, 2009May 31, 2026BARBE, MARY Freporter.nih.gov
Displacement-guided focused ultrasound for pain modulation.NIHNational Institute of Biomedical Imaging and Bioengineering2025$3,220,027August 21, 2025July 31, 2028KONOFAGOU, ELISA E.reporter.nih.gov
Probing the biochemical mechanism of amyloid diseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$3,210,642May 1, 1993June 30, 2026KELLY, JEFFERY Wreporter.nih.gov
Peripherally-restricted non-addictive cannabinoids for cancer pain treatmentNIHNational Institute of Neurological Disorders and Stroke2023$3,174,343August 1, 2023July 31, 2025SPIGELMAN, IGORreporter.nih.gov
Microphysiological Model of Human Cardiac Sympathetic InnervationNIHNational Heart, Lung, and Blood Institute2022 to 2025$3,165,021July 1, 2022June 30, 2027KIM, DEOK-HOreporter.nih.gov
Modulation of pain mechanisms by cannabis-derived phytochemicals.NIHNational Center for Complementary & Integrative Health2021 to 2025$3,150,461December 1, 2020November 30, 2026SETO, TODD Breporter.nih.gov
Clinical Development of SBS-147: First-in-class Oral Arylepoxamide Agonist for PainNIHNational Institute on Drug Abuse2025$3,138,031July 1, 2025June 30, 2027ASHWORTH, JUDYreporter.nih.gov
The glymphatic system at the crossroad of integrative health approaches inchronic painNIHNational Center for Complementary & Integrative Health2021 to 2025$3,067,927August 1, 2021May 31, 2026NEDERGAARD, MAIKENreporter.nih.gov
Accelerating the non-opioid analgesic AFA-281 clinical development with TABA-supported business developmentNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$3,049,862August 1, 2025April 30, 2026XIE, XINMIN SIMONreporter.nih.gov
Development of a Novel Chemokine Receptor Antagonist Peptide as a Non-Opioid Treatment for Relief of Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021$2,999,505September 15, 2021August 31, 2023RUFF, MICHAEL Rreporter.nih.gov
Comprehensive Phenotyping of Specific Populations of Spinal Neurons Processing Cutaneous Information Before and After InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,973,851September 16, 2016August 31, 2026KOERBER, H RICHARDreporter.nih.gov
Development of KLS-13019 for Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,970,772September 30, 2021August 31, 2025BRENNEMAN, DOUGLAS ERICreporter.nih.gov
Dissection of SARM1-Induced Axon Degeneration and Cell DeathNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,966,646September 1, 2014May 31, 2029MILBRANDT, JEFFREY Dreporter.nih.gov
A staged, comprehensive investigation for developing insular deep brain stimulation to treat refractory chronic painNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,959,839September 20, 2022December 31, 2028ELIAS, WILLIAM JEFFREYreporter.nih.gov
Mechanism and optimization of CBD-mediated analgesic effects (Diversity Supplement)NIHNational Center for Complementary & Integrative Health2021 to 2023$2,902,023September 15, 2019June 30, 2025HE, ZHIGANGreporter.nih.gov
Characterization of the Properties and Mechanisms of Photobiomodulation-Induced Axonal Block and Evaluation as a Treatment for Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,878,214May 1, 2021April 30, 2027MOFFITT, MICHAELreporter.nih.gov
Identifying novel therapeutic targets for chronic neck pain: RNA-sequencing in human painful atlanto-axial arthropathyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,872,749September 1, 2021August 31, 2026CURATOLO, MICHELEreporter.nih.gov
Voltage-Gated Calcium Channels in Nociceptors and MechanoreceptorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,837,880August 2, 2006July 31, 2027LIPSCOMBE, DIANEreporter.nih.gov
Targeting Schwann cell dysfunction and repair signaling in chemotherapy induced painful peripheral neuropathyNIHNational Institute of Dental & Craniofacial Research2024$2,833,086September 20, 2024August 31, 2027YE, YIreporter.nih.gov
Long-term Suppressive Valacyclovir Treatment for Herpes Zoster OphthalmicusNIHNational Eye Institute2022 to 2023$2,806,822September 30, 2016July 31, 2023COHEN, ELISABETH Jreporter.nih.gov
A Self-Tuning Liquid Metal Coil Conforming to Movement for High-Resolution Brachial Plexus MRINIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,775,927May 16, 2022February 28, 2027BALLON, DOUGLAS Jreporter.nih.gov
Mechanisms of Pain Associated with Trigeminal Nerve InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,760,934August 1, 2021June 30, 2027GOLD, MICHAEL Sreporter.nih.gov
Validation of Prenatal Rabbit Hypoxia Ischemia as a Model of Cerebral Palsy-induced PainNIHNational Institute of Neurological Disorders and Stroke2023$2,727,001September 19, 2023August 31, 2026QUINLAN, KATHARINA ANNreporter.nih.gov
Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imagingNIHNational Cancer Institute2025$2,714,830August 6, 2025July 31, 2030ZHENG, QINreporter.nih.gov
Study of Activity-Dependent Sympathetic SproutingNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,675,718May 4, 2004June 30, 2026ZHANG, JUN-MINGreporter.nih.gov
Elucidating cutaneous mechanosensory circuits, from development to diseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,664,003September 1, 2016August 31, 2024GINTY, DAVID Dreporter.nih.gov
Multi-isotope Hybrid PET/CT Imaging of Peripheral Artery Disease in DiabetesNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,663,222December 19, 2022November 30, 2025SINUSAS, ALBERT Jreporter.nih.gov
The Neurospan Bridge: A Device for Peripheral Nerve RepairNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,594,464March 15, 2023August 31, 2027KOFFLER, YACOVreporter.nih.gov
Anatomic, Physiologic and Transcriptomic Mechanisms of Neuropathic Pain in Human DRGNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,590,497April 15, 2020February 28, 2026DOUGHERTY, PATRICK Mreporter.nih.gov
Targeting checkpoint inhibitors for pain controlNIHNational Institute of Neurological Disorders and Stroke2023$2,569,851September 21, 2023August 31, 2026JI, RU-RONGreporter.nih.gov
Multi-Omic Biomarkers for Neuropathic Pain Secondary to ChemotherapyNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$2,568,308September 30, 2020August 31, 2025ROTROFF, DANIELreporter.nih.gov
Evaluation of Small-Fiber Polyneuropathy in YouthNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,545,391August 15, 2015May 31, 2026OAKLANDER, ANNE LOUISEreporter.nih.gov
Effects of Fish Oil ± Salsalate on the Omega-3 Index and the Circulating Lipodome of Omega-3 Polyunsaturated Fatty Acid Metabolites in Patients with Type 2 Diabetes and Diabetic NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,534,893February 7, 2022January 31, 2027YOREK, MARK A.reporter.nih.gov
Metabolic coupling between Schwann cells and axons is functionally distinct from myelination and is disrupted in obesity, prediabetes, and diabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$2,531,361August 23, 2022June 30, 2027FELDMAN, EVA LUCILLEreporter.nih.gov
Development of A Focused Ultrasound Device for Noninvasive, Peripheral Nerve Blockade to Manage Acute PainNIHNational Institute of Biomedical Imaging and Bioengineering2023$2,505,537September 30, 2023September 29, 2026ANDERSON, THOMAS A.reporter.nih.gov
New Inactivators of GABA Aminotransferase for Epilepsy and Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,498,237July 15, 2021June 30, 2026SILVERMAN, RICHARD Breporter.nih.gov
Amygdala pain mechanismsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,469,334December 15, 2021November 30, 2026NEUGEBAUER, VOLKERreporter.nih.gov
Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain with Machine Learning to Predict Treatment ResponseNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$2,446,704August 1, 2015March 31, 2027FREGNI, FELIPEreporter.nih.gov
Patterns and predictors of symptoms, falls, and functioning across treatment and recovery in patients treated with neurotoxic chemotherapy for cancerNIHNational Cancer Institute2021 to 2024$2,446,165September 10, 2020June 30, 2026WINTERS-STONE, KERRI Mreporter.nih.gov
Imaging neuroglial mechanisms of neuropathic pain-opioid interaction in HIVNIHNational Institute on Drug Abuse2021 to 2022$2,441,399July 15, 2018July 31, 2025LOGGIA, MARCO LUCIANOreporter.nih.gov
Neuropeptidergic Inhibition of Spinal Pain TransmissionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,433,566September 10, 2002November 30, 2026TAYLOR, BRADLEY K.reporter.nih.gov
Genipin’s ECM Crosslinking Action as an Agent to Prevent Neurodegeneration in Familial DysautonomiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,424,350April 1, 2021June 30, 2030ZELTNER, NADJAreporter.nih.gov
Immunomodulatory Therapy for Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,420,195September 1, 2018August 31, 2025CHEN, RIDONGreporter.nih.gov
Development of Pathology-activated Drugs for Treatment of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2022$2,408,109September 20, 2022August 31, 2024GRACE, PETER Mreporter.nih.gov
A Double-Blind, Randomized, Controlled Trial of Epidural Conus Medullaris Stimulation to Alleviate Pain and Augment Rehabilitation in Patients with Subacute Thoracic Spinal Cord Injury (SCI)NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$2,395,166September 15, 2020April 30, 2027LAD, SHIVANAND Preporter.nih.gov
Disruption of Homeostatic Neuroimmune Interactions in Descending Circuitry in the Development of Pain ChronicityNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,391,373July 1, 2020June 30, 2026WEI, FENGreporter.nih.gov
Axonal transport and chemotherapy induced peripheral neuropathyNIHNational Cancer Institute2022 to 2025$2,319,802April 1, 2016June 30, 2027SEGAL, ROSALIND A.reporter.nih.gov
Regulation of Peripheral Neuropathic Pain by B CellsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,308,227March 15, 2022February 28, 2027GRACE, PETER Mreporter.nih.gov
Focused Ultrasound Neuromodulation of Dorsal Root Ganglion for Noninvasive Mitigation of Low Back PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2024$2,304,494September 25, 2019August 31, 2025RIEKE, VIOLAreporter.nih.gov
Development of MRGPRX1 positive allosteric modulators as non-addictive therapies for neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,299,466September 30, 2019August 31, 2024TSUKAMOTO, TAKASHIreporter.nih.gov
Discovery and Validation of a Novel Response Biomarker Signature for Painful Peripheral NeuropathyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,298,698September 1, 2022April 30, 2026NEMENOV, MIKHAIL I.reporter.nih.gov
Exploring the Functions of tRNA Synthetases in the Nucleus and their Relationship to CMTNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,285,535April 1, 2020March 31, 2025YANG, XIANG-LEIreporter.nih.gov
Peripheral and Central Pathways of α3 Glycine Receptors as Non-Opioid Molecular Targets to Treat PainNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,282,554May 1, 2022January 31, 2027XU, YANreporter.nih.gov
Link extracellular function of tRNA synthetase with pathological mechanism of diseaseNIHNational Institute of General Medical Sciences2021 to 2025$2,260,000June 1, 2021August 31, 2026YANG, XIANG-LEIreporter.nih.gov
Elucidating cellular mechanisms underlying neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,259,716June 17, 2022May 31, 2027OPAL, PUNEETreporter.nih.gov
Molecular and Computational Dissection of Cold NociceptionNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,254,672July 15, 2019July 31, 2029CYMBALYUK, GENNADY Sreporter.nih.gov
Exploring the EphB2-NMDA receptor interaction in spinal cord injury-induced neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,249,630September 1, 2018June 30, 2029LEPORE, ANGELO C.reporter.nih.gov
Validation of neuronal senescence as a target for chronic pain in agingNIHNational Institute on Aging2024$2,249,392September 15, 2024August 31, 2027TAWFIK, VIVIANNE Lreporter.nih.gov
Control of calcium flux and mitochondrial fission by the Charcot Marie Tooth disease protein Mfn2.NIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,243,240January 1, 2021December 31, 2025VAN DER BLIEK, ALEXANDER Mreporter.nih.gov
The Effect of Medical Cannabis Laws on Health Care Use in Insured Populations with PainNIHNational Institute on Drug Abuse2021 to 2023$2,228,671July 1, 2019April 30, 2026ABRAHAM, AMANDA Jreporter.nih.gov
Selective Kv7.2/3 activators for the treatment of neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021$2,200,680September 1, 2021March 31, 2022SIGNORE, ARMANDOreporter.nih.gov
Functional and histological changes to peripheral innervation following spinal cord stimulation in patients with painful diabetic neuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,189,785September 12, 2023July 31, 2028TOWNSEND, KRISTY Lreporter.nih.gov
Supplement to Promote Diversity, Inclusion, and Career Development of a Female ScientistNIHNational Cancer Institute2021 to 2022$2,183,954December 31, 2021August 23, 2023ALEMAN GUILLEN, FERNANDOreporter.nih.gov
The role of neuroinflammation in human peripheral neuropathic painNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$2,171,620July 1, 2022February 28, 2028LOGGIA, MARCO LUCIANOreporter.nih.gov
Modulating single cell types in the sensory nervous systemNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,152,157July 1, 2022June 30, 2027SCHMIDT, ERIC Wreporter.nih.gov
Epigenetic dysregulation in diabetic enteric neuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$2,115,203January 1, 2021December 31, 2025ORDOG, TAMASreporter.nih.gov
Supplement to Pathogenesis of HIV-associated sensory neuropathyNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,080,000September 30, 2021August 31, 2026YUAN, SUBOreporter.nih.gov
Development of MMP-9 inhibitory monoclonal antibodies to relieve neuropathic painNIHNational Institute of Neurological Disorders and Stroke2025$2,079,796August 11, 2025July 31, 2027GE, XINreporter.nih.gov
Spinal Cord Nociceptive Circuits that Deliver Outputs to the Brain to Initiate PainNIHNational Center for Complementary & Integrative Health2023 to 2024$2,078,643September 15, 2020May 19, 2025GINTY, DAVID Dreporter.nih.gov
Leveraging machine learning to improve risk prediction for chemotherapy inducedneuropathyNIHNational Cancer Institute2021 to 2024$2,077,393June 1, 2020May 31, 2026ADAMS, ALYCE SOPHIAreporter.nih.gov
Dissecting the role of mPFC dynorphin circuits in the modulation of different pain statesNIHNational Institute of Neurological Disorders and Stroke2024$2,068,842September 20, 2024August 31, 2027SHEETS, PATRICK Lreporter.nih.gov
Analytical Validation of Non-native Transthyretin (NNTTR) As A Candidate Biomarker for Transthyretin Amyloidoses (ATTR)NIHNational Institute of Neurological Disorders and Stroke2021 to 2023$2,068,762April 1, 2020November 30, 2024JIANG, XINreporter.nih.gov
Modulation of the prefrontal cortical network in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,066,533April 1, 2020March 31, 2025MARTINA, MARCOreporter.nih.gov
Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) Syndrome in the Diabetic, Neuropathic FootNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$2,064,907March 1, 2016June 30, 2028HASTINGS, MARY Kreporter.nih.gov
Glycosylation in ocular surface health and diseaseNIHNational Eye Institute2021 to 2025$2,064,667August 1, 2016July 31, 2028ARGUESO, PABLOreporter.nih.gov
Interhemispheric Communication and Compensation in Peripheral Nerve InjuryNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,062,400December 15, 2020November 30, 2026EGGEBRECHT, ADAM THOMASreporter.nih.gov
The Genetics of the Neuromuscular Junction: Mechanisms and Disease ModelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,053,330August 1, 2025May 31, 2027BURGESS, ROBERT W.reporter.nih.gov
Cannabidiol/Palmitoylethanolamide sublingual tablets for the treatment of Painful Diabetic Peripheral NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2024$2,051,325September 20, 2023July 31, 2025KIMLESS, DEBRAreporter.nih.gov
Novel biologic to treat chemotherapy-induced neuropathic painNIHNational Cancer Institute2022 to 2023$2,049,964September 19, 2022August 31, 2025KOGAN, YAKOVreporter.nih.gov
Development of a novel small molecule RPN13 inhibitor and therapeutic for advanced ovarian cancer patientsNIHNational Cancer Institute2023 to 2024$2,047,415September 1, 2023August 31, 2025ANCHOORI, RAVI KUMARreporter.nih.gov
Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the ElbowNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2024$2,042,098September 25, 2019August 31, 2025CHUNG, KEVIN Creporter.nih.gov
Validation of a new large-pore channel as a novel target for neuropathic painNIHNational Institute of Neurological Disorders and Stroke2023$2,039,202September 25, 2023August 31, 2026QIU, ZHAOZHUreporter.nih.gov
The Roles of Neuronal Activity in Peripheral Nerve MyelinationNIHNational Institute on Deafness and Other Communication Disorders2021 to 2024$2,036,232April 20, 2020March 31, 2025CORFAS, GABRIELreporter.nih.gov
A first in class, mechanism-guided, cell-based therapy for complex regional pain syndromeNIHNational Institute of Neurological Disorders and Stroke2022$2,033,135September 24, 2022August 31, 2025CHENG, JIANGUOreporter.nih.gov
Mechanism of Nociception Induced by Innocuous Cold in Trigeminal SystemNIHNational Institute of Dental & Craniofacial Research2021 to 2024$2,030,519August 11, 2008July 31, 2025GU, JIANGUOreporter.nih.gov
Selection of a lead LPAR1 antagonist for treatment of diabetic neuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$2,026,502May 20, 2021April 30, 2025BEATON, GRAHAMreporter.nih.gov
Clinical investigation of topical delivery of a muscarinic receptor antagonist for the prevention of chemotherapy-induced peripheral neuropathyNIHNational Cancer Institute2021 to 2022$2,000,000September 1, 2021August 31, 2024HANSEN, ANGELAreporter.nih.gov
mHealth app for caregiver instruction in manual therapy for chemotherapy-induced peripheral neuropathyNIHNational Cancer Institute2024 to 2025$1,998,767August 18, 2022May 31, 2026COLLINGE, WILLIAM B.reporter.nih.gov
Neuroinflammation in Wallerian Degeneration and Regeneration: Neutrophils Play a Primary Role as PhagocytesNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,986,349August 1, 2020October 31, 2025ZIGMOND, RICHARD Ereporter.nih.gov
Translating Novel Peripheral Nerve Allograft Technologies Toward Clinical UseNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,980,377May 1, 2023April 30, 2027BITTNER, GEORGE DAVISreporter.nih.gov
Therapeutic antibodies for treating chemotherapy induced peripheral neuropathic painNIHNational Cancer Institute2021 to 2022$1,979,001September 25, 2019April 30, 2025SCHWIMMER, LAUREN JENNIFERreporter.nih.gov
Acupuncture for Chemothrapy-induced Peripheral Neuropathy Treatment (ACT)TrialNIHNational Cancer Institute2021 to 2023$1,973,105December 1, 2020November 30, 2023BAO, TINGreporter.nih.gov
Chronic Chemotherapy Peripheral Neuropathy: Role of Neuroplasticity and StressNIHNational Cancer Institute2021 to 2023$1,973,060September 9, 2019August 31, 2024LEVINE, JON DAVIDreporter.nih.gov
The Role of Cellular Senescence in Carpal Tunnel SyndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,971,867September 10, 2020November 30, 2026GINGERY, ANNEreporter.nih.gov
Inflammation associated with HIV infection: role of receptor cross-talkNIHNational Institute on Drug Abuse2021 to 2023$1,971,180September 30, 2019June 30, 2025ROGERS, THOMAS Jreporter.nih.gov
Pharmacological validation of adenylyl cyclase 1 as a drug target for chronic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,963,598December 1, 2020November 30, 2025FLAHERTY, DANIEL PATRICKreporter.nih.gov
Mitofusin agonists to prevent Charcot-Marie-Tooth disease 2ANIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,960,976September 30, 2019August 31, 2024DORN, GERALD W.reporter.nih.gov
Mitofusin Agonists to Treat Neurodegenerative DiseaseNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$1,954,883May 15, 2022April 30, 2025HAUGER, DEBORAH ANNreporter.nih.gov
Coordination of mucosal immune response to enteric bacterial pathogens by nociceptive innervationNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,954,430April 1, 2020March 31, 2025REARDON, COLINreporter.nih.gov
Lymphotoxin-Beta Receptor Peripheral Signaling Regulates the Transition to Inflammation and Neuropathy-Induced Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,953,071May 15, 2020March 31, 2026AKOPIAN, ARMEN Nreporter.nih.gov
Non-addictive Angiotensin AT2 inhibitors for neuropathic pain reliefNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,940,013June 1, 2020May 31, 2025KATRITCH, VSEVOLODreporter.nih.gov
Thermal Imaging Modality for Detection of Large and Small Fiber Diabetic Peripheral Neuropathy.NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,938,578July 1, 2015December 31, 2024SOLIZ, PETER Nreporter.nih.gov
Measuring cellular senescence to predict and prevent peripheral neuropathyNIHNational Institute on Aging2021 to 2023$1,928,919September 15, 2021August 31, 2025MITIN, NATALIAreporter.nih.gov
Targeting neuronal transport to ameliorate vincristine neurotoxicityNIHNational Cancer Institute2023 to 2025$1,918,934July 11, 2023June 30, 2028HU, SHUIYINGreporter.nih.gov
Mechanisms of Axon-Schwann cell interactionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,913,450July 15, 2021May 31, 2026MONK, KELLY Rreporter.nih.gov
CRCNS: Computational Model of Chronic Pain Analgesia via Closed-Loop Peripheral Nerve StimulationNIHNational Center for Complementary & Integrative Health2021 to 2025$1,909,461July 1, 2021June 30, 2027SARMA, SRIDEVI V.reporter.nih.gov
Imaging Epigenetic Dysregulation in Patients with Low Back PainNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021$1,899,288September 26, 2019August 31, 2025WEY, HSIAO-YINGreporter.nih.gov
Multimodal wireless electrical stimulation for tissue regenerationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,893,913May 1, 2022April 30, 2027LI, SONGreporter.nih.gov
Targeting methylglyoxal-induced diabetic neuropathic pain through the integrated stress responseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,890,818September 7, 2023July 31, 2028YOUSUF, MUHAMMAD SAADreporter.nih.gov
Genomic Studies in Charcot-Marie-Tooth DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,886,243September 15, 2019July 31, 2025ZUCHNER, STEPHANreporter.nih.gov
Development of LPA5 Antagonists as AnalgesicsNIHNational Institute of Neurological Disorders and Stroke2023$1,881,741July 6, 2023June 30, 2025ZHANG, YANANreporter.nih.gov
Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) TrialNIHNational Cancer Institute2021 to 2023$1,873,647April 1, 2021September 30, 2023BAO, TINGreporter.nih.gov
Molecular Determinants of Synaptic Plasticity in Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,868,197August 15, 2017November 30, 2027PAN, HUI-LINreporter.nih.gov
Development of Tissue Engineered Neuromuscular Interfaces from GalSafe NeuronsNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,866,060January 15, 2022March 31, 2027KATIYAR, KRITIKAreporter.nih.gov
Structure and Mechanism of the Kinesin-3 Motor KIF1ANIHNational Institute of General Medical Sciences2023 to 2025$1,865,013September 1, 2023June 30, 2027GENNERICH, ARNEreporter.nih.gov
Allele-specific inactivation for dominant negative NEFL MutationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,855,975August 15, 2021June 30, 2027JUDGE, LUKE Mreporter.nih.gov
Synergistic Enhancement of Peripheral Nerve Defect Repair using Peptide Functionalized Aligned Nanofiber ConduitsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,840,426June 1, 2022May 31, 2027BECKER, MATTHEW Lreporter.nih.gov
Generation of Tissue Engineered Nerve Grafts from GalSafe Porcine NeuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,835,055September 30, 2018August 31, 2024KATIYAR, KRITIKAreporter.nih.gov
Investigating the Effects of Spinal Cord Injury and Rehabilitative Training on Corticospinal Circuits Controlling Contextual Opioid Analgesic ToleranceNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,829,756September 1, 2025November 30, 2025CAFFERTY, WILLIAM B.reporter.nih.gov
The Gut Microbiome and Serum Metabolites as a Biological Mechanism Underlying Pain in Kidney Transplantation (Biome-KT)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,824,012May 15, 2023February 29, 2028LOCKWOOD, MARKreporter.nih.gov
Lipid signaling in supraspinal pain pathwaysNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,822,223April 1, 2020March 31, 2026SHEETS, PATRICK Lreporter.nih.gov
Targeting aldose reductase: A Phase IIb/III trial for the novel use of Epalrestat to treat Congenital Disorders of Glycosylation (PMM2-CDG)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$1,805,996May 3, 2022April 30, 2025PERLSTEIN, ETHANreporter.nih.gov
Compromised LDH activity causes motor deficits and hastens ALS progressionNIHNational Institute on Aging2023 to 2025$1,805,312July 1, 1996January 31, 2028MILBRANDT, JEFFREY Dreporter.nih.gov
Development and Application of Nicotinic Acetylcholine Receptor Targeted Peptides for Biomedical ResearchNIHNational Institute of General Medical Sciences2021 to 2024$1,799,500April 1, 2020January 31, 2026MCINTOSH, J MICHAELreporter.nih.gov
Translation Control of Pain PlasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,795,589March 15, 2010January 31, 2025PRICE, THEODORE J.reporter.nih.gov
Mechanism of Enteric NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,794,310August 1, 2009July 31, 2028SRINIVASAN, SHANTHI Kreporter.nih.gov
Pre-clinical validation of 3D-printed nerve conduits for pediatric peripheral nerve repairNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2023 to 2025$1,788,090June 27, 2023March 31, 2028CHEN, SHAOCHENreporter.nih.gov
Dance-based Avenues to Advance Nonpharmacologic treatment of Chemotherapy Effects (DAANCE): a multicenter trialNIHNational Institute on Aging2024 to 2025$1,775,424September 20, 2024August 31, 2029WORTHEN-CHAUDHARI, LISE C.reporter.nih.gov
The conserved mechanisms underlying different types of chronic painNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,764,266August 15, 2022July 31, 2027LI, LINGYONGreporter.nih.gov
Investigating the role of MAP2 in chemotherapy-induced peripheral neurotoxicityNIHNational Cancer Institute2023 to 2025$1,751,883January 1, 2023December 31, 2027STAFF, NATHAN Preporter.nih.gov
Dermatomal Mapping with Spinal Cord Functional Magnetic Resonance ImagingNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,744,537September 1, 2023May 31, 2028WEBER, KENNETH ARNOLDreporter.nih.gov
Developing a new DFU dressingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2023$1,741,462May 17, 2022January 31, 2025CHIEN, SUFANreporter.nih.gov
Development of a novel analgesic for mixed inflammatory and neuropathic pain statesNIHNational Institute of Neurological Disorders and Stroke2021$1,734,409September 15, 2021August 31, 2023GHETTI, ANDREAreporter.nih.gov
Non-Opioid Post-Operative Pain Management Using Bupivacaine-loaded Poly(ester urea) MeshNIHNational Institute of General Medical Sciences2021$1,730,751September 13, 2021August 31, 2023YU, JIAYIreporter.nih.gov
Development of novel Amadorins for Diabetic Peripheral NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,723,731September 19, 2018July 31, 2024KHALIFAH, RAJA Greporter.nih.gov
Prevention of paclitaxel-induced peripheral neuropathy with nilotinibNIHNational Cancer Institute2021 to 2023$1,723,403April 17, 2019March 31, 2025HU, SHUIYINGreporter.nih.gov
Cannabidiol and terpenoid interactions in amygdalar regulation of pain statesNIHNational Center for Complementary & Integrative Health2022 to 2025$1,717,472May 1, 2022January 31, 2027LAND, BENJAMINreporter.nih.gov
Schwann cell activation in oral cancer perineurial invasion and neuropathic painNIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,714,072April 1, 2020March 31, 2026YE, YIreporter.nih.gov
Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) TrialNIHNational Cancer Institute2023 to 2025$1,709,232April 1, 2021September 30, 2026BAO, TINGreporter.nih.gov
Development and validation of an intraoperative imaging agent for the peripheral nervous systemNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2023$1,698,454June 15, 2020February 28, 2024PILLARSETTY, NAGAVARAKISHOREreporter.nih.gov
Neuro-immune mechanisms of minor cannabinoids in inflammatory and neuropathic painNIHNational Center for Complementary & Integrative Health2021 to 2023$1,692,291September 15, 2019June 30, 2025HELLMAN, JUDITHreporter.nih.gov
Transduction of Mechanical Stimuli in Myelination and Peripheral Nerve RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,672,924January 15, 2020December 31, 2025POITELON, YANNICKreporter.nih.gov
Home-Based Physical Activity Intervention for Taxane-Induced CIPNNIHNational Cancer Institute2021 to 2023$1,668,669September 19, 2019December 31, 2024VISOVSKY, CONSTANCE G.reporter.nih.gov
Development of an Integrated Risk Prediction Model of Taxane-induced Peripheral NeuropathyNIHNational Cancer Institute2023 to 2025$1,662,683January 1, 2023December 31, 2027HERTZ, DANIEL LOUISreporter.nih.gov
Photoacoustic and epigenetic nerve scaffold for nerve regenerationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,662,078May 18, 2022March 31, 2027YAN, SUreporter.nih.gov
Folding, Misfolding, and Function of PMP22NIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,650,616April 1, 2016January 31, 2028SANDERS, CHARLES Rreporter.nih.gov
Uncovering the roles of oxysterols in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,648,312July 15, 2022May 31, 2028SALVEMINI, DANIELAreporter.nih.gov
Auricular Point Acupressure to Manage Chemotherapy Induced NeuropathyNIHNational Cancer Institute2022 to 2024$1,647,689September 1, 2020May 31, 2026JOHNSON, CONSTANCE MARGARETreporter.nih.gov
Developing mechanism-based strategies to treat chemotherapy-induced peripheral neuropathyNIHNational Cancer Institute2022 to 2025$1,647,046January 13, 2022December 31, 2026GEISLER, STEFANIEreporter.nih.gov
JAX-Gladstone, SCGE Disease Models Studies SupplementNIHNational Institute of Environmental Health Sciences2021 to 2022$1,641,672September 25, 2018June 30, 2023CONKLIN, BRUCE Rreporter.nih.gov
Profiling Translation in Nociceptor PlasticityNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,634,786September 15, 2020May 31, 2030CAMPBELL, ZACHARYreporter.nih.gov
Inhibiting RIPK1 with Necrostatin-1 for Safe and Effective Pain TreatmentNIHNational Institute of Neurological Disorders and Stroke2022$1,633,790September 5, 2022August 31, 2025SHEN, SHIQIANreporter.nih.gov
Discovery and characterization of selective GIRK1/2 activators and their evaluation in preclinical models of painNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,623,792April 1, 2022March 31, 2028HOPKINS, COREY R.reporter.nih.gov
Diffusion MRI Biomarkers of Peripheral Nerve TraumaNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$1,622,655May 1, 2023April 30, 2025DORTCH, RICHARDreporter.nih.gov
Stem Cell Surface Modification to Promote Nerve RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,617,912January 15, 2021December 31, 2026JIA, XIAOFENGreporter.nih.gov
Safe Direct Current Stimulator (SDCS) technology for blocking chronicperipheral painNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,611,872April 15, 2020March 31, 2025FRIDMAN, GENE YEVGENYreporter.nih.gov
Regulation of SCI-induced pain by macrophages and exerciseNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,610,456September 18, 2017June 30, 2028DETLOFF, MEGAN Rreporter.nih.gov
Investigating the contributions of voltage gated sodium channels to oxaliplatin induced neuropathyNIHNational Institute of Neurological Disorders and Stroke2022$1,610,258September 21, 2022December 31, 2022YAROV-YAROVOY, VLADIMIR Mreporter.nih.gov
Sensory Phenotyping to Enhance Neuropathic Pain Drug DevelopmentNIHNational Institute of Neurological Disorders and Stroke2023$1,600,475September 21, 2023August 31, 2025FREEMAN, ROYreporter.nih.gov
An innovative device for management of neuropathic pain after spinal cord injuryNIHNational Institute of Neurological Disorders and Stroke2024$1,594,319September 19, 2024August 31, 2026LI, SHENGreporter.nih.gov
Cortical Signature and Modulation of PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,587,995September 30, 2018February 29, 2024WANG, FANreporter.nih.gov
Development of CNS-Active 5-HT3R Antagonists for the Treatment of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2024$1,587,553July 5, 2024June 30, 2026ELGENDY, BAHAAreporter.nih.gov
Novel Circuits and Mechanisms of Descending Pain ModulationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,579,926December 15, 2022November 30, 2027USACHEV, YURIY Mreporter.nih.gov
Endoplasmic Reticulum Stress Responses in PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,578,107February 15, 2020January 31, 2026ROMERO-SANDOVAL, E. ALFONSOreporter.nih.gov
Impact of Schwann Cell Pathology on Axon Structure and FunctionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,574,423December 1, 2022November 30, 2027SALZER, JAMESreporter.nih.gov
Developing GPR37 activators as non-opioid pain therapeuticsNIHNational Institute of Neurological Disorders and Stroke2022$1,573,491April 1, 2022March 31, 2025LA, JUN-HOreporter.nih.gov
Cellular and Genetic Mechanisms of Autoimmune Diabetes Associated NeuritisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,572,053September 1, 2023June 30, 2028RACINE, JEREMY Jreporter.nih.gov
Developing equilibrative nucleoside transporter inhibitors as non-opioid pain therapeuticsNIHNational Institute of Neurological Disorders and Stroke2024$1,563,778September 12, 2024August 31, 2026LEE, SEOK-YONGreporter.nih.gov
Therapeutic and Mechanistic Evaluation of Cannabis sativa Terpenes in Neuropathic PainNIHNational Center for Complementary & Integrative Health2021 to 2025$1,560,823July 1, 2021April 30, 2027STREICHER, JOHN MICHAELreporter.nih.gov
Topical Neurokinin-1 Receptor Antagonist as an Effective Non-addictive Analgesic for Ocular PainNIHNational Institute of Neurological Disorders and Stroke2024$1,559,917August 5, 2024July 31, 2026DANA, REZAreporter.nih.gov
Dissecting the Diverse Roles of Importin α at the Plasma MembraneNIHNational Institute of General Medical Sciences2022 to 2025$1,554,644August 1, 2022July 31, 2027BROWNLEE, CHRISTOPHER WILLIAMreporter.nih.gov
Regenerative and degenerative responses to axonal injuryNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,553,880April 1, 2010May 31, 2026COLLINS, CATHERINE Areporter.nih.gov
Laminin Receptors and Signals in Schwann CellsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,546,694July 1, 2003January 31, 2025SIM, FRASER JAMESreporter.nih.gov
Novel mechanisms regulating protein interaction and painNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,542,406December 15, 2019November 30, 2023DALVA, MATTHEW Breporter.nih.gov
Extracellular mechanism regulating synaptic function and pain plasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,533,165September 1, 2019January 8, 2024DALVA, MATTHEW Breporter.nih.gov
Sleep fragmentation by brief awakenings as a surrogate to measure neuropathic spontaneous painNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,527,707April 1, 2020March 31, 2025LATREMOLIERE, ALBAN Areporter.nih.gov
Cardiovascular and neuromuscular issues in chronic painNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,525,114August 1, 2024May 31, 2028AMANN, MARKUSreporter.nih.gov
Development of selective GPR34 antagonists for the treatment of neuropathic painNIHNational Institute of Neurological Disorders and Stroke2024$1,511,970September 19, 2024August 31, 2026SALVEMINI, DANIELAreporter.nih.gov
Planning Study for the Development of Sigma 2 ligands as AnalgesicsNIHNational Institute of Neurological Disorders and Stroke2023$1,510,066September 11, 2023August 31, 2025TIDGEWELL, KEVIN JOSEPHreporter.nih.gov
Pronociceptive and antinociceptive opioid mechanisms in the central nucleus of the amygdalaNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,507,449August 15, 2019June 30, 2025NAVRATILOVA, EDITAreporter.nih.gov
Role of TLR4-lipid rafts in nociceptionNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,503,288January 17, 2024December 31, 2028YAKSH, TONY L.reporter.nih.gov
Choline-dependent metabolism in PNS myelinationNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,502,243September 1, 2020May 31, 2026KIM, HAESUN Areporter.nih.gov
Laboratory Developed Test (LDT) to Support Clinical Evaluation of a Drug for Painful Diabetic NeuropathyNIHNational Institute of Neurological Disorders and Stroke2025$1,500,000September 20, 2021May 31, 2027RICHARDSON, THOMAS Preporter.nih.gov
FDA Phase 1 Development of a Novel Nonopioid Cell and Tissue Permeable Peptide Therapeutic for Epigenetic Reprogramming of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2025$1,500,000August 7, 2025July 31, 2027NESTI, EDMUNDreporter.nih.gov
Trans-BBB AAV9 gene therapy targeting CNS neuropathy of MPS INIHNational Institute of Neurological Disorders and Stroke2025$1,499,504September 16, 2025August 31, 2027MCCARTY, DOUGLAS Mreporter.nih.gov
Enhancing Physical Therapy: Noninvasive Brain Stimulation System for Treating Carpal Tunnel SyndromeNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2023$1,494,958September 21, 2022August 31, 2025WAGNER, TIMOTHY ANDREWreporter.nih.gov
Development of Pathology-activated Drugs for Treatment of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2024$1,485,925September 20, 2022August 31, 2027GRACE, PETER Mreporter.nih.gov
Establishing Oprm1 exon 7-associated variants as novel therapeutic targets for mitigating adverse effects of clinically used mu opioids without altering analgesia in pain managementNIHNational Institute on Drug Abuse2024 to 2025$1,483,529September 30, 2024May 31, 2029PAN, YING-XIANreporter.nih.gov
Schwann Cell Reprogramming after Nerve InjuryNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,478,294June 1, 2023May 31, 2028SVAREN, JOHN Preporter.nih.gov
Discovery of the Biomarker Signature for Neuropathic Corneal PainNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$1,470,840August 1, 2019July 31, 2025HAMRAH, PEDRAMreporter.nih.gov
ACVR1 sensory neuron-specific signaling in neuropathic pain and injury-induced heterotopic ossificationNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2025$1,470,746September 1, 2023June 30, 2028YU, XIAOBINGreporter.nih.gov
Myelin Autoantigens in Neuropathic PainNIHNational Institute of Dental & Craniofacial Research2021 to 2022$1,467,994September 1, 2018August 31, 2024SHUBAYEV, VERONICAreporter.nih.gov
A Novel LRP1 Agonist, SP16, as a Therapeutic Treatment in Preventing Chemotherapy-Induced Peripheral NeuropathyNIHNational Cancer Institute2024 to 2025$1,464,067September 19, 2022August 31, 2027GELBER, COHAVAreporter.nih.gov
Painful Versus Insensate Diabetic NeuropathyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,463,724January 1, 2003January 31, 2027WRIGHT, DOUGLAS Ereporter.nih.gov
Temporal effects of inflammation on the autonomic control of circulation during exercise in type 2 diabetic ratsNIHNational Heart, Lung, and Blood Institute2021 to 2023$1,453,944January 1, 2019December 31, 2024STONE, AUDREY Jreporter.nih.gov
Identifying mechanisms that regulate local axon vulnerability to pathological degenerationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,444,182April 1, 2022March 31, 2027SUMMERS, DANIELreporter.nih.gov
Functional Analysis of O-GlcNAc using Synthetic Protein ChemistryNIHNational Institute of General Medical Sciences2021 to 2024$1,442,331August 1, 2015July 31, 2025PRATT, MATTHEW ROBERTreporter.nih.gov
Investigating the neutrophil-sensory neuron crosstalk in lung cancerNIHNational Cancer Institute2023 to 2025$1,435,793July 1, 2023June 30, 2028JIN, CHENGCHENGreporter.nih.gov
Mechanistic Study of Pain Inhibition by Activation of Non-nociceptive Afferent FibersNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,429,390March 1, 2019January 31, 2025GUAN, YUNreporter.nih.gov
mRNA Splicing Modulation in Familial DysautonomiaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,426,656July 1, 2016June 30, 2024SLAUGENHAUPT, SUSAN Areporter.nih.gov
Sphingolipid Signaling and Chemotherapy-Induced Peripheral NeurotoxicityNIHNational Cancer Institute2021 to 2023$1,422,549April 1, 2021August 31, 2023KROETZ, DEANNA Lreporter.nih.gov
Generalizing genome editing for rare disease-causing variantsNIHOffice of the Director, National Institutes of Health2025$1,416,375September 18, 2025August 31, 2028NEWBY, GREGORY A.reporter.nih.gov
Spinal cord stimulation for the attenuation of chemotherapy-induced peripheral neuropathy and enhanced chemotherapeutic efficacyNIHNational Cancer Institute2021 to 2025$1,412,130July 1, 2021June 30, 2026SIVANESAN, EELLANreporter.nih.gov
Identification of a Novel DRG-Specific Long Noncoding RNA and its Role in Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,410,785April 15, 2021March 31, 2027HU, HUIJUANreporter.nih.gov
RNA-Protein Interactions in NociceptionNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,410,642April 1, 2022March 31, 2027HARRISON, BENJAMINreporter.nih.gov
Anti-CV2 autoantibodies unmask a CRMP5/GluN2B pain signaling hubNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,402,246May 14, 2022December 31, 2026MOUTAL, AUBINreporter.nih.gov
Discovery of Biomarker Signatures Prognostic for Neuropathic Pain after Acute Spinal Cord InjuryNIHNational Institute of Neurological Disorders and Stroke2024$1,401,149September 1, 2019June 30, 2026HERGENROEDER, GEORGENE Wreporter.nih.gov
Brain Structural Biomarkers of Risk and Resilience to Pain ChronificationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,384,895December 1, 2022November 30, 2027GEHA, PAULreporter.nih.gov
Response-contingent learning to modulate synaptic plasticity for spinal cord injuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$1,384,314September 1, 2025August 31, 2028SONG, SHANGreporter.nih.gov
Novel SMARD1 Mouse Models: Characterization and Evaluation of Potential Therapeutic TargetsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,380,377February 1, 2020January 31, 2026LORSON, CHRISTIAN L.reporter.nih.gov
Targeting of Alpha7 nAChR for therapeutic effectsNIHNational Institute of General Medical Sciences2021 to 2023$1,377,281May 1, 2000June 30, 2024PAPKE, ROGER Lreporter.nih.gov
Biomarker development in patients with HNPPNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$1,376,111January 15, 2022December 31, 2025CHEN, YONGSHENGreporter.nih.gov
The Role of the Complement System in Spinal Mechanisms of Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,375,806June 15, 2019May 31, 2025USACHEV, YURIY Mreporter.nih.gov
A Symptom Management Efficacy Study to Reduce Distal Neuropathic PainNIHNational Institute of Nursing Research2021 to 2022$1,368,660August 27, 2018May 31, 2025ANASTASI, JOYCE Kreporter.nih.gov
Development of positive TMEM97 modulators for treating neuropathic painNIHNational Institute of Neurological Disorders and Stroke2023$1,352,240August 1, 2023July 31, 2025MARTIN, STEPHENreporter.nih.gov
Novel expression of MHC class II on DRG neurons and its role in promoting antinociceptive CD4+ T cells in females during chemotherapy-induced peripheral neuropathyNIHNational Cancer Institute2022 to 2025$1,351,202August 15, 2022July 31, 2027GOODE, DIANA Jreporter.nih.gov
Mechanisms of Epigenetic Plasticity in Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,344,471April 1, 2023March 31, 2028PAN, HUI-LINreporter.nih.gov
Targeting Endosomal Receptors for Treatment of Chronic PainNIHNational Institute of Dental & Craniofacial Research2021 to 2024$1,337,416September 1, 2024August 31, 2025BUNNETT, NIGEL Wreporter.nih.gov
Therapeutic Electrical Stimulation Using Wireless, Resorbable Implants to Accelerate Diaphragm Muscle Reinnervation after Phrenic NeuropathyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,326,010May 15, 2024April 30, 2029FRANZ, COLINreporter.nih.gov
Investigating the Pathogenic Role of Tubulin Post-translational Modifications in CIPNNIHNational Cancer Institute2024 to 2025$1,322,244September 1, 2024August 31, 2029BARTOLINI, FRANCESCAreporter.nih.gov
The Role of ESCRTs in Regulating Nervous System FunctionNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,306,650December 1, 2019November 30, 2025WILSON, SCOTT MICHAELreporter.nih.gov
Understanding Neuronal Cell type-Specific Dysregulation in Familial DysautonomiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,296,290July 1, 2016June 30, 2029SLAUGENHAUPT, SUSAN Areporter.nih.gov
Translational control of stress response signalingNIHNational Institute of General Medical Sciences2023 to 2025$1,286,370September 22, 2023August 31, 2028RYOO, HYUNG Dreporter.nih.gov
Novel injectable analgesic delivery system for musculoskeletal pain managementNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,280,693August 1, 2019June 30, 2025NAIR, LAKSHMI Sreporter.nih.gov
Cellular mechanisms of antidepressant drug actions in neuropathic pain modelsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,272,357August 1, 2019July 1, 2022ZACHARIOU, VENETIAreporter.nih.gov
Acupuncture for Chemothrapy-induced Peripheral Neuropathy Treatment (ACT) TrialNIHNational Cancer Institute2024 to 2025$1,263,296December 1, 2023November 30, 2025BAO, TINGreporter.nih.gov
Role of Primary Sensory Neuron CaMKII Signaling in Regulation of PainNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,259,355May 1, 2024April 30, 2028PAN, BINreporter.nih.gov
α9α10 Nicotinic Acetylcholine Receptors in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,248,720August 1, 2024June 30, 2029RILEY, ANDREWreporter.nih.gov
Peripheral Nerve Regulation of Pancreas Cancer ProgressionNIHNational Cancer Institute2024 to 2025$1,245,096July 1, 2024June 30, 2029SALOMAN, JAMI LYNNreporter.nih.gov
Longitudinal assessment of the role of interoception in chemotherapy-induced peripheral neuropathy (CIPN) along the cancer chemotherapy continuumNIHNational Cancer Institute2024 to 2025$1,244,265September 4, 2024August 31, 2029KLECKNER, IAN ROBERTreporter.nih.gov
Neuron vasculature interactions in painNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,243,506September 9, 2024August 31, 2029ZHANG, JUN-MINGreporter.nih.gov
Studies on RGS4-Regulated Pathways in Models of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,241,005April 5, 2024March 31, 2029ZACHARIOU, VENETIAreporter.nih.gov
Schwann cell derived exosomes improve diabetic peripheral neuropathy in type II diabetic miceNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,233,471September 15, 2020June 30, 2025WANG, LEIreporter.nih.gov
The Effect of High Intensity Interval Training and Surgical Weight Loss On Distal Symmetric Polyneuropathy OutcomesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,223,000July 6, 2018February 28, 2025CALLAGHAN, BRIAN CHRISTOPHERreporter.nih.gov
Acute-to-Chronic Transition in Ergonomic Muscle Pain: Nociceptor MechanismsNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2022$1,221,295March 5, 2013January 31, 2023LEVINE, JON DAVIDreporter.nih.gov
Sarm1 and neural regulation of boneNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,220,859January 13, 2023November 30, 2026SCHELLER, ERICA LYNNreporter.nih.gov
Brain Mechanisms of Chronic Low-Back Pain: Specificity and Effects of Aging and SexNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,214,654April 1, 2023March 31, 2028GEHA, PAULreporter.nih.gov
Midbrain cholinergic modulation of pain statesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,207,359June 1, 2023May 31, 2028MCGEHEE, DANIEL Sreporter.nih.gov
Sphingolipid Signaling and Chemotherapy-Induced Peripheral NeurotoxicityNIHNational Cancer Institute2023 to 2025$1,201,082April 1, 2021March 31, 2027KROETZ, DEANNA Lreporter.nih.gov
Trans-synaptic signaling complex in amygdala pain mechanismsNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,198,149August 1, 2020December 31, 2023DRAVID, SHASHANK MANOHARreporter.nih.gov
Analgesic efficacy of single and combined minor cannabinoids and terpenesNIHNational Center for Complementary & Integrative Health2021 to 2023$1,188,750September 15, 2019June 30, 2025WARD, SARA Jreporter.nih.gov
Mitochondrial Regulation of Nociceptor FunctionNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,187,938February 15, 2023January 31, 2028MOLLIVER, DEREK Creporter.nih.gov
NEURAXIAL AAVS TARGETING DRG CHANNELS INVOLVED IN CHRONIC POST INFLAMMATORY PAINNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,182,994January 1, 2024December 31, 2028YAKSH, TONY L.reporter.nih.gov
Understanding the role of patient-derived Ighmbp2 mutations in neurodegeneration and pre-rRNA processingNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,181,939January 1, 2024December 31, 2028LORSON, CHRISTIAN L.reporter.nih.gov
Initial Development of AEG-1 inactivation as a possible strategy for pain treatmentNIHNational Institute of Neurological Disorders and Stroke2022$1,179,675May 1, 2022April 30, 2024DAMAJ, M. IMADreporter.nih.gov
The role of neuroimmune interactions in the pathogenesis of chronic painNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$1,172,064September 10, 2018December 31, 2024YANG, GUANGreporter.nih.gov
Hierarchically-Structured Conduits with Programmed Release of Neurotrophic Factors for Repairing Large Defects in Thick NervesNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,171,620May 15, 2023April 30, 2028XIA, YOUNANreporter.nih.gov
Spatiotemporal Coding in the Pain Circuit Along the Spine-brain ContinuumNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,164,262September 15, 2018November 30, 2023SAAB, CARL Yreporter.nih.gov
Metabolic control of gut-brain axis in Familial DysautonomiaNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$1,161,056September 1, 2018May 31, 2025COPIE, VALERIEreporter.nih.gov
A Novel Pathogenic Pathway for Diabetic KeratopathyNIHNational Eye Institute2023 to 2025$1,148,250September 1, 2018December 31, 2027KARAMICHOS, DIMITRIOSreporter.nih.gov
microRNA regulation of NMNAT-mediated Neuroprotection against Peripheral Neuropathy and Chronic PainNIHNational Center for Complementary & Integrative Health2022 to 2023$1,145,822August 16, 2019June 30, 2025ZHAI, RONG GRACEreporter.nih.gov
Long-acting Injectable Protein Delivery System for Functional Repair of Peripheral Nerve InjuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,143,739January 1, 2023November 30, 2028MAO, HAI-QUANreporter.nih.gov
Neuroimaging and Connectome Analysis as a Diagnostic and Prognostic Biomarker of SCI Induced Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,141,192December 26, 2023November 30, 2028ALIZADEH, MAHDIreporter.nih.gov
A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After TraumaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,139,738September 1, 2021August 31, 2027ELFAR, JOHNreporter.nih.gov
REST-mediated regulation of opioid receptors in chronic pain mouse modelsNIHNational Institute on Drug Abuse2024 to 2025$1,135,224July 1, 2020June 30, 2027MAJUMDER, SADHANreporter.nih.gov
Feature selection of DNA methylation biosignatures for neuropathy with comorbid drug abuse in the setting of HIV infectionNIHNational Institute on Drug Abuse2021 to 2022$1,132,485September 15, 2018May 31, 2025XU, KEreporter.nih.gov
Duloxetine to Prevent Oxaliplatin-Induced Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase II to Phase III StudyNIHNational Cancer Institute2021 to 2024$1,106,695January 10, 2019December 31, 2025SMITH, ELLEN MARY LAVOIEreporter.nih.gov
Neural Mechanisms of Cancer PainNIHNational Cancer Institute2021 to 2023$1,105,536June 1, 2019May 31, 2025SIMONE, DONALDreporter.nih.gov
Developing Chemical Probes for Inflammatory PainNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,092,815August 1, 2022April 30, 2028ELGENDY, BAHAAreporter.nih.gov
Single and Double AAV Somatic Gene Amelioration of Mouse Models of LAMA2 Related DystrophyNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2025$1,091,199August 7, 2025July 31, 2028YURCHENCO, PETER DANAreporter.nih.gov
Tracking HIV Infection & Alcohol Abuse CNS Comorbidity with NeuroimagingNIHNational Institute on Alcohol Abuse and Alcoholism2021$1,088,145September 30, 2007August 31, 2023PFEFFERBAUM, ADOLFreporter.nih.gov
Neuroinflammation Grading and Adjusting of Spinal Sensorimotor Circuitries in Response to Remote Injuries in Peripheral NervesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,087,068April 1, 2020January 31, 2024ALVAREZ, FRANCISCO Jreporter.nih.gov
The role of SARM1 in neuroinflammation-mediated axonal damageNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,083,048April 10, 2024February 28, 2029MILBRANDT, JEFFREY Dreporter.nih.gov
Investigating the role of gut extracellular vesicles in diabetic peripheral neuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,082,069March 1, 2024January 31, 2028LIU, XIANSHUANGreporter.nih.gov
Modulation of CSF1R Signaling to Treat Inflammatory NeuropathiesNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,081,356December 15, 2023November 30, 2028SHEIKH, KAZIM Areporter.nih.gov
Comprehensive gene and DNA variant curation for neuromuscular diseasesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,079,672June 15, 2021May 31, 2025ZUCHNER, STEPHANreporter.nih.gov
Neuroimmune mechanisms of a humanized CCK-B receptor scFv as therapy for chronic pain patientsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,076,942June 1, 2022August 31, 2023WESTLUND-HIGH, KARIN N.reporter.nih.gov
HIV Tat-associated Sensory Neuropathy and the Contribution of Toll-like Receptor PathwayNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,065,000September 19, 2023August 31, 2028CAO, LINGreporter.nih.gov
Enduring enhancement of neuropathic pain by early post-trauma morphineNIHNational Institute on Drug Abuse2021 to 2022$1,060,844July 1, 2018April 30, 2025WATKINS, LINDAreporter.nih.gov
Anti-nociceptive actions of CART II in chemotherapy-induced peripheral neuropathyNIHNational Cancer Institute2023 to 2025$1,054,425June 9, 2023May 31, 2028BUCZYNSKI, MATTHEW WALLACEreporter.nih.gov
Metabolic regulation of KLHL proteins through O-glycosylationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,053,916June 15, 2019March 31, 2024CHI, JEN-TSAN ASHLEYreporter.nih.gov
Angiotensin Signaling Underlies Myeloid and Sensory Disruption in DiabetesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2024 to 2025$1,049,838May 2, 2024April 30, 2028SHEPHERD, ANDREW JOHNreporter.nih.gov
Molecular mechanisms of somatosensory adaptation to prolonged hypothermiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,047,112December 21, 2023November 30, 2028BAGRIANTSEV, SVIATOSLAVreporter.nih.gov
15-LOX-1 as a druggable target in the acute to chronic pain transition of rheumatoid arthritisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2023$1,041,920July 1, 2019May 31, 2025GREGUS, ANN MARIEreporter.nih.gov
Endocannabinoid Biosynthesis in Inflammation and PainNIHNational Institute on Drug Abuse2023 to 2025$1,034,700February 1, 2024January 31, 2029HSU, KU-LUNGreporter.nih.gov
Anti-inflammatory Effects of Novel Minor Cannabinoids and Terpenes on Cellular and Murine Models of HIV and HIV ProteinsNIHNational Institute on Drug Abuse2021 to 2023$1,034,538September 30, 2020July 31, 2025PARIS, JASON RICHARDreporter.nih.gov
Dorsal horn circuits for mechanical allodyniaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,032,136June 15, 2019March 31, 2024SEAL, REBECCA Preporter.nih.gov
Mechanisms of Central SensitizationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,028,014April 1, 2018March 31, 2025GEREAU, ROBERT Wreporter.nih.gov
Technology development for closed-loop deep brain stimulation to treat refractory neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$1,022,290July 1, 2019June 30, 2024CHANG, EDWARDreporter.nih.gov
Role of dorsal root ganglion FTO, a RNA demethylase, in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$1,019,768July 15, 2019April 30, 2025TAO, YUAN-XIANGreporter.nih.gov
Role of a Fatty Acid Chaperone in Schwann Cell MyelinationNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$1,019,124February 1, 2024January 31, 2029BELIN, SOPHIEreporter.nih.gov
A role for the p75 neurotrophin receptor in Schwann cell regulation of sensory neuronsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$1,018,116July 1, 2018May 31, 2024CARTER, BRUCE Dreporter.nih.gov
Investigation of neural ensembles driving pain chronificationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,017,362December 15, 2022November 30, 2027BEIER, KEVIN Treporter.nih.gov
MECHANISMS OF TRPV4-MEDIATED NEUROPATHIC PAINNIHNational Institute on Alcohol Abuse and Alcoholism2021 to 2022$1,010,646September 15, 2018June 30, 2023HU, HONGZHENreporter.nih.gov
Thermal Imaging Modality for Detection of Large and Small Fiber Diabetic Peripheral NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022$1,001,136September 22, 2022August 31, 2024SOLIZ, PETER Nreporter.nih.gov
Endogenous opioid regulation of locus coeruleus-mediated analgesiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$996,499July 1, 2024June 30, 2029MCCALL, JORDAN G.reporter.nih.gov
Primary afferent plasticity in chronic painNIHNational Institute of Dental & Craniofacial Research2021 to 2022$994,822September 1, 2018June 30, 2024CHUNG, MAN-KYOreporter.nih.gov
Regeneration of Epidermal Nerves in Human Diabetic NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021$985,495September 30, 2014April 30, 2023HANSEN, ANGELAreporter.nih.gov
Development of a Novel Medication for Alcohol Use Disorder with an Active IND Dual Inhibitor of T-Type Calcium Channel and Soluble Epoxide HydrolaseNIHNational Institute on Alcohol Abuse and Alcoholism2023 to 2024$982,702September 25, 2023August 31, 2025XIE, XINMIN SIMONreporter.nih.gov
Identification of a novel DRG-specific long noncoding RNA and its role in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$981,820April 15, 2021March 31, 2023HU, HUIJUANreporter.nih.gov
Emerging Neuroviruses and Neurological Inflammatory DiseasesNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$974,046July 15, 2019April 30, 2025PARDO-VILLAMIZAR, CARLOS Areporter.nih.gov
TNF in Injury and Repair Processes Following Traumatic SCINIHNational Institute of Neurological Disorders and Stroke2024 to 2025$962,884April 1, 2005April 30, 2029BETHEA, JOHN ROLANDreporter.nih.gov
An exercise intervention to Reduce Neuropathic Pain and Brain Inflammation after Spinal Cord InjuryNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2023$957,523September 1, 2019August 31, 2024LINNMAN, CLASreporter.nih.gov
microRNA regulation of NMNAT-mediated Neuroprotection against Peripheral Neuropathy and Chronic PainNIHNational Center for Complementary & Integrative Health2024$949,953July 10, 2024June 30, 2025ZHAI, RONG GRACEreporter.nih.gov
Complement in Paclitaxel-induced peripheral neuropathyNIHNational Cancer Institute2021 to 2024$936,532March 5, 2020February 28, 2026XU, JIJUNreporter.nih.gov
Role of Gut Microbiome in HIV/Opioid Induced Peripheral NeuropathyNIHNational Institute on Drug Abuse2021 to 2022$929,035July 15, 2018May 31, 2024ROY, SABITAreporter.nih.gov
Molecular Mechanism of Brain Regulation of Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$928,980February 1, 2020July 31, 2025ZHU, MICHAEL Xreporter.nih.gov
Determine Functions of Mammalian Touch-sensing Neurons in Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$923,704July 1, 2013June 30, 2023LUO, WENQINreporter.nih.gov
Sympathetic Function in Neural InjuriesNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$923,372September 23, 2021November 30, 2026WARD, PATRICIA JILLreporter.nih.gov
Trans-synaptic signaling complex in amygdala pain mechanismsNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$920,784August 1, 2020July 31, 2026DRAVID, SHASHANK MANOHARreporter.nih.gov
Tacrolimus-eluting nerve guidance conduit for enhanced regeneration in critical-sized peripheral nerve injuriesNIHNational Institute of Neurological Disorders and Stroke2025$919,846September 30, 2019April 30, 2027AZAPAGIC, AZURreporter.nih.gov
Adenylyl cyclase signaling in persistent painNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$919,730August 1, 2019April 30, 2025MOLLIVER, DEREK Creporter.nih.gov
(PQ12) Enhancement of DNA repair in neurons via a targeted APE1 small molecule modifier to decrease and reverse chemotherapy-induced peripheral neuropathy (CIPN)NIHNational Cancer Institute2021 to 2022$912,411September 10, 2018August 31, 2023FEHRENBACHER, JILL Creporter.nih.gov
Non-invasive Electrical Stimulation as a Therapy for Diabetic KeratopathyNIHNational Eye Institute2025$896,046September 1, 2025August 31, 2027YANG, MENGLUreporter.nih.gov
Sexual dimorphism of neuroimmune interactions in temporomandibular joint disorders pain: contribution of a newly identified female-specific pain signaling axis IL23/IL17A/TRPV1NIHNational Institute of Dental & Craniofacial Research2021 to 2022$888,913September 1, 2018June 30, 2024CHEN, YONGreporter.nih.gov
Develop pan-specific antibody against mutant glycyl-tRNA synthetase for treating CMT2DNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$887,500January 1, 2021March 31, 2024YANG, XIANG-LEIreporter.nih.gov
Identification of botanical hHv1 channel blockers as analgesics for neuropathic painNIHNational Center for Complementary & Integrative Health2024 to 2025$873,042June 8, 2023June 30, 2027ZHAO, RUIMINGreporter.nih.gov
A Female Specific Role of RGSz1 in Modulation of Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$871,461July 1, 2020January 31, 2023ZACHARIOU, VENETIAreporter.nih.gov
A Novel Role for Nav1.1 in Mammalian ThermosensationNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$871,280August 1, 2022July 31, 2027GRIFFITH, THEANNE NICOLEreporter.nih.gov
Role of immune cells in skin reinnervation by collateral sprouting after peripheral nerve injuryNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$870,578April 1, 2024March 31, 2029JEON, SANGMINreporter.nih.gov
Peripheral Mechanisms of Kappa Opioid Receptor-Mediated Cold HypersensitivityNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$869,391April 1, 2022March 31, 2024AL-HASANI, REAMreporter.nih.gov
The role of cell-specific TLR-4 signaling in oxaliplatin-induced peripheral neuropathyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$864,952September 15, 2018June 30, 2025WHITE, FLETCHER Areporter.nih.gov
5-HT3 receptor antagonists for neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$853,082February 15, 2018January 31, 2024HAROUTOUNIAN, SIMONreporter.nih.gov
Developing multi-cue piezoelectric PVDF-TrFE biomaterials for peripheral nerve repairNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$851,956January 1, 2024December 31, 2028HARRIS, GREG Mreporter.nih.gov
tRNA Gene Replacement Therapy for tRNA-Synthetase Related Charcot-Marie-Tooth DisorderNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$841,280July 1, 2024March 31, 2027BURGESS, ROBERT W.reporter.nih.gov
Development of Angiotensin AT2 inhibitors for neuropathic pain reliefNIHNational Institute of Neurological Disorders and Stroke2025$818,360June 1, 2025May 31, 2029KATRITCH, VSEVOLODreporter.nih.gov
Thoracic Neuromodulation for Diabetic GastroparesisNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$813,671July 15, 2022May 31, 2025SHARMA, AMOLreporter.nih.gov
Role of Complex Sphingolipids in Diabetic NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$808,306August 15, 2020May 31, 2026FRIDMAN, VERAreporter.nih.gov
The role of acute excitation of sensory neurons in the development of paclitaxel-induced peripheral neuropathyNIHNational Cancer Institute2024 to 2025$805,748September 1, 2024August 31, 2029YANG, QINGreporter.nih.gov
Pathogenesis in Segmental DemyelinationNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$804,961June 1, 2023May 31, 2028HU, BOreporter.nih.gov
Primary sensory neuron-targeted block of Cav3.2 for treatment of chronic neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$799,591August 1, 2021July 31, 2024YU, HONGWEIreporter.nih.gov
Optimization of Non Invasive Brain Stimulation for Diabetic Neuropathic PainNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$793,388December 10, 2020May 31, 2024WAGNER, TIMOTHY ANDREWreporter.nih.gov
In-depth characterization of B-cell dysfunction in chronic inflammatory demyelinating polyneuropathyNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$792,143April 1, 2024March 31, 2029ROY, BHASKARreporter.nih.gov
REST-mediated epigenomic and transcriptomic signatures in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$791,971September 15, 2019July 31, 2024MAJUMDER, SADHANreporter.nih.gov
Store-operated channels in the nervous systemNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$790,169February 13, 2007June 30, 2024PRAKRIYA, MURALIreporter.nih.gov
Complex Autonomic Neuropathic Dysfunction Leading to Gastrointestinal and Immune Effects in People with HIV (CANDLE)NIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$789,126September 1, 2025June 30, 2030ROBINSON-PAPP, JESSICAreporter.nih.gov
Developing Chemical Probes for Inflammatory PainNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$784,934August 1, 2022September 30, 2023ELGENDY, BAHAAreporter.nih.gov
Chronic Pain Diagnosis and Treatment in Torture SurvivorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$779,760September 15, 2020August 31, 2025KAUR, GUNISHAreporter.nih.gov
Neuropathic Pain-induced Depression: the Role of mPFC EndocannabinoidsNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$779,283August 15, 2019January 31, 2024PAN, BINreporter.nih.gov
Development and Validation of a Clinically Relevant Animal Pain ModelNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$777,168July 1, 2020June 30, 2024SHEN, SHIQIANreporter.nih.gov
The impact of medical cannabis on pain and inflammation in people living with HIVNIHNational Institute on Drug Abuse2021 to 2024$776,700July 15, 2021February 28, 2026SLAWEK, DEEPIKAreporter.nih.gov
Examining the roles A-delta LTMRs and BDNF signaling play in neuropathic pain after SCINIHNational Institute of Neurological Disorders and Stroke2021 to 2022$773,164July 1, 2018June 30, 2024GARRAWAY, SANDRA M.reporter.nih.gov
Dronabinol for the reduction of chronic pain and inflammation in people with sickle cell diseaseNIHNational Heart, Lung, and Blood Institute2022 to 2025$773,104June 1, 2022May 31, 2027CURTIS, SUSANNAreporter.nih.gov
Myelin Junction Therapy in Peripheral NeuropathiesNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$769,539March 15, 2020December 31, 2025LI, JUNreporter.nih.gov
Small Molecule Tools for Modulating Membrane RaftsNIHNational Institute of General Medical Sciences2021 to 2022$764,342September 1, 2020August 31, 2024KENWORTHY, ANNE Kreporter.nih.gov
Community Health and Neuropathy: Nutritional and Environmental Links in Zambia (CHANNELZ)NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$756,277August 5, 2021July 31, 2025KVALSUND, MICHELLE POWELLreporter.nih.gov
Biomechanical treatment of carpal tunnel syndrome for Hispanic womenNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$755,220August 1, 2024July 31, 2025LI, ZONG-MINGreporter.nih.gov
Molecular Dissection of the Axonal Injury Response for Regeneration and NeuroprotectionNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$752,000April 1, 2020March 31, 2023WATKINS, TRENTreporter.nih.gov
A Novel Pharmacologic Approach to Treat CMT1XNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$751,688September 15, 2020August 31, 2024DOBROWSKY, RICK Treporter.nih.gov
Molecular Dissection of the Axonal Injury Response for Regeneration and NeuroprotectionNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$747,663April 1, 2023March 31, 2026WATKINS, TRENTreporter.nih.gov
Sphingolipid and Fatty Acid Biology in Prediabetes and NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$747,000September 15, 2021May 31, 2024RUMORA, AMY E.reporter.nih.gov
The Role of Tau Phosphorylation in Diabetic Peripheral NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2025$747,000September 1, 2025August 31, 2028NICHOLS, JAMES Mreporter.nih.gov
Fn14, non-canonical NF-kappaB and downstream signaling in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$746,244September 1, 2018May 31, 2024SIMARD, J. MARCreporter.nih.gov
Pain in Hidradenitis Suppurativa: Phenotypes and Stakeholder PerspectivesNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2022 to 2025$743,903July 8, 2022June 30, 2027ORENSTEIN, LAUREN ANNE VIGILreporter.nih.gov
Nuclear lipid-sensor in Type II Diabetic NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$742,138March 1, 2018May 31, 2023MANSUY AUBERT, VIRGINIEreporter.nih.gov
Human Disease Modeling of Glaucomatous NeuropathyNIHNational Eye Institute2021 to 2022$739,625March 1, 2019February 28, 2025AHMAD, IQBALreporter.nih.gov
Myelin Junction Therapy in Peripheral NeuropathiesNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$735,456March 15, 2020July 11, 2022LI, JUNreporter.nih.gov
Development of a Splicing Modulator Compound for Familial DysautonomiaNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$735,428May 1, 2023May 31, 2027SLAUGENHAUPT, SUSAN Areporter.nih.gov
Integrative Medicine for Pain Management in Sickle Cell DiseaseNIHNational Center for Complementary & Integrative Health2021 to 2023$734,872July 17, 2018August 31, 2025WANG, YINGreporter.nih.gov
Abnormal Gene Splicing in Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$734,116July 1, 2020December 31, 2025LOPEZ SOTO, EDUARDO JAVIERreporter.nih.gov
PQ12 Targeting HDAC6 for Chemotherapy-Induced Neuropathy and ChemobrainNIHNational Cancer Institute2021 to 2023$726,198May 22, 2018April 30, 2025GRACE, PETER Mreporter.nih.gov
Vagal and spinal afferent mapping of rat and human hearts in health and diseaseNIHNational Heart, Lung, and Blood Institute2025$726,035September 12, 2025June 30, 2030CHENG, ZIXI JACKreporter.nih.gov
Molecular and cellular mechanisms of cold allodyniaNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$721,876July 1, 2018September 11, 2024MCKEMY, DAVID Dreporter.nih.gov
Peripheral Mechanisms of Kappa Opioid Receptor-Mediated Cold HypersensitivityNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$720,183April 1, 2022March 31, 2027AL-HASANI, REAMreporter.nih.gov
Biomechanics and strength in the distal upper limb influence median nerve health in manual wheelchair usersNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2025$719,222August 11, 2025April 30, 2030MURRAY, WENDY Mreporter.nih.gov
Risk Factors and Outcomes Associated with Late-Life Diabetic Peripheral NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2024$712,576April 1, 2020April 30, 2025HICKS, CAITLIN WHITNEYreporter.nih.gov
Exosomes and platinum-induced peripheral neuropathyNIHNational Cancer Institute2021 to 2022$709,918July 1, 2018June 30, 2024ZHANG, ZHENG GANGreporter.nih.gov
The Flint Neuropathy Study: assessing diagnostic and management gaps in a Black, low-income population-supplementNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$708,801January 1, 2025June 30, 2028ELAFROS, MELISSAreporter.nih.gov
Estradiol and Zoster Associated Orofacial PainNIHNational Institute of Dental & Craniofacial Research2021 to 2022$706,716April 1, 2018March 31, 2025KRAMER, PHILLIP Rreporter.nih.gov
Targeting GPCRs in amygdalar and cortical neural ensembles to treat pain aversionNIHNational Institute of Neurological Disorders and Stroke2024$705,382September 15, 2020June 30, 2025SCHERRER, GREGORYreporter.nih.gov
Structural Biology of Connexin Membrane ChannelsNIHNational Institute of General Medical Sciences2022 to 2023$705,371July 1, 2020June 30, 2025YEAGER, MARK JAYreporter.nih.gov
Chemokine-receptor profiling for painful diabetic neuropathy in biological samples from human clinical trialsNIHNational Institute of Neurological Disorders and Stroke2021$700,128September 20, 2021December 15, 2023RICHARDSON, THOMAS Preporter.nih.gov
Optimization of an HCN1-Selective Inverse Agonist for the Treatment of Peripheral Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2022 to 2023$698,818September 23, 2022August 31, 2025FOX, STEVEN Rreporter.nih.gov
Targeting TLR4-lipid rafts to prevent postoperative painNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$698,036September 21, 2023August 31, 2025DOUGHERTY, PATRICK Mreporter.nih.gov
Structural Biology of Connexin Membrane ChannelsNIHNational Institute of General Medical Sciences2021 to 2022$693,855July 1, 2020October 31, 2022YEAGER, MARK JAYreporter.nih.gov
Opioid-Sparing Non-Surgical, Bioresorbable Nerve Stimulator for Pain ReliefNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$693,472September 20, 2023August 31, 2025CUI, XINYAN TRACYreporter.nih.gov
Hippo Regulation of Peripheral Myelination and Nerve RepairNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$693,438June 1, 2018March 31, 2025SON, YOUNG-JINreporter.nih.gov
Cellular and Molecular Role of CXCR4 signaling in Painful Diabetic NeuropathyNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$691,250December 1, 2017November 30, 2022MENICHELLA, DANIELA Mreporter.nih.gov
Green Light Therapy for Chronic PainNIHNational Center for Complementary & Integrative Health2021 to 2022$690,750July 16, 2018May 31, 2023IBRAHIM, MOHAB Mreporter.nih.gov
A new pathway of spinal neurons in neuropathic pain induced by HIV with opioidNIHNational Institute on Drug Abuse2021 to 2022$690,750September 30, 2018July 31, 2024HAO, SHUANGLINreporter.nih.gov
The Molecular Mechanism and Therapeutics in Axon RegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$682,500September 30, 2018December 31, 2023ENGLISH, ARTHUR W.reporter.nih.gov
Central and Peripheral Measures of Pain: Recovery and ResistanceNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021$676,623July 1, 2015November 30, 2022KOHANE, DANIEL Sreporter.nih.gov
The role of the glial engulfment receptor Jedi1 in regulating sensory neuron functionNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$676,059April 1, 2018March 31, 2024CARTER, BRUCE Dreporter.nih.gov
Validation of Fibroblast-Derived PI16 as a Novel Target for pain TreatmentNIHNational Institute of Neurological Disorders and Stroke2024$675,862September 30, 2020August 31, 2025SHEPHERD, ANDREW JOHNreporter.nih.gov
Development of non-opioid, non-addictive analgesics for treating neuropathic painNIHNational Institute of Neurological Disorders and Stroke2025$675,107March 18, 2025January 31, 2030THAKUR, GANESH Areporter.nih.gov
Developing evidence-based objective tools for managing children with auditory neuropathy spectrum disorderNIHNational Institute on Deafness and Other Communication Disorders2025$670,525May 1, 2025April 30, 2030HE, SHUMANreporter.nih.gov
Auricular Point Acupressure to Manage Chemotherapy Induced NeuropathyNIHNational Cancer Institute2021$669,413September 1, 2020October 31, 2021YEH, CHAO HSINGreporter.nih.gov
Mesolimbic adaptations underlying altered reward sensitivity in neuropathic painNIHNational Institute on Drug Abuse2025$668,131August 15, 2025April 30, 2030CREED, MEAGHAN Creporter.nih.gov
Dissection of NTSR2/calcium channel signaling as a non-opioid spinal analgesic mechanism for the treatment of high impact chronic painNIHNational Institute of Neurological Disorders and Stroke2025$664,772February 1, 2025November 30, 2029PATWARDHAN, AMOL Mreporter.nih.gov
HAPPINESS: cHAnging the Perceived Pain INtensity in populations with Spinal cord injury and with health disparitiesNIHNational Center for Complementary & Integrative Health2024$664,224February 23, 2024January 31, 2027VAN DE WINCKEL, ANN Lreporter.nih.gov
Selective Probes for Alpha9* Nicotinic Acetylcholine ReceptorsNIHNational Institute of Neurological Disorders and Stroke2025$650,079March 1, 2025February 28, 2030THAKUR, GANESH Areporter.nih.gov
Validation of blocking TSP4/Cava2d1 interaction as a new target for neuropathic painNIHNational Institute of Dental & Craniofacial Research2021 to 2022$639,395September 24, 2019June 30, 2024LUO, ZHIGANG DAVIDreporter.nih.gov
Molecular mechanisms underlying mitochondria-lysosome membrane contact sites in neuronal function and neurodegenerationNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$633,556September 30, 2018November 30, 2023WONG, YVETTEreporter.nih.gov
A Female Specific Role of RGSz1 in Modulation of Chronic PainNIHNational Institute of Neurological Disorders and Stroke2022 to 2024$633,045July 1, 2020June 30, 2025ZACHARIOU, VENETIAreporter.nih.gov
Role of Primary Sensory Neuron CaMKII Signaling in Regulation of PainNIHNational Institute of Neurological Disorders and Stroke2023$621,180June 1, 2023January 31, 2024PAN, BINreporter.nih.gov
Nociplastic mechanisms in temporomandibular disorders: Separating nociception from painNIHNational Institute of Dental & Craniofacial Research2024$610,399August 1, 2024July 31, 2026HARPER, DANIEL ELLIOTTreporter.nih.gov
Novel Path to Chronic Sensorimotor Dysfunction and Treatment for ChemotherapyNIHNational Cancer Institute2021 to 2022$604,292September 13, 2018July 31, 2024COPE, TIMOTHY Creporter.nih.gov
Midcareer K24 Award for Mentoring and Patient-Oriented ResearchNIHNational Institute on Drug Abuse2023 to 2025$602,500February 1, 2023January 31, 2028COFFIN, PHILLIP Oreporter.nih.gov
Damage-associated molecular patterns in chemotherapy toxicityNIHNational Cancer Institute2025$601,091April 1, 2025March 31, 2030EISENMANN, ERIC DANIELreporter.nih.gov
Investigation of Mechanical Allodynia Circuitry by the Nature of the InjuryNIHNational Institute of Neurological Disorders and Stroke2025$597,999March 15, 2025January 31, 2030SEAL, REBECCA Preporter.nih.gov
Senescent stromal cells drive chemotherapy-induced peripheral neuropathyNIHNational Institute on Aging2025$589,106June 1, 2025March 31, 2030STEWART, SHEILA Areporter.nih.gov
Probing the role of serotonin in neuropathic pain with flexible carbon microelectrode arraysNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$583,463June 1, 2022March 31, 2028CASTAGNOLA, ELISAreporter.nih.gov
The role of cell-specific TLR4 in Diabetic Peripheral NeuropathyNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2024$577,200July 8, 2022May 31, 2025BURTON, MICHAEL Dreporter.nih.gov
Mapping Neural Recovery: Visualizing Peripheral Nerve Regeneration and Brain Plasticity Post-Peripheral Nerve InjuryNIHNational Institute of Neurological Disorders and Stroke2025$567,037August 1, 2025July 31, 2030BEREZIN, MIKHAIL Y.reporter.nih.gov
Neural Coding and Control of Pain Detection in Somatosensory CortexNIHNational Institute of Neurological Disorders and Stroke2025$560,934April 1, 2025March 31, 2030SAAB, CARL Yreporter.nih.gov
Novel Interventions for Chemotherapy-Induced NeuropathyNIHNational Institute on Aging2021 to 2022$553,341August 15, 2021December 31, 2023WORTHEN-CHAUDHARI, LISE C.reporter.nih.gov
Regenerative and degenerative responses to axonal injuryNIHNational Institute of Neurological Disorders and Stroke2021$546,913April 1, 2010May 31, 2022COLLINS, CATHERINE Areporter.nih.gov
Development of selective calpain-1 inhibitors for chronic painNIHNational Institute of Neurological Disorders and Stroke2021$546,376July 1, 2021December 31, 2023NWANKWO, JENNIFER Oreporter.nih.gov
Spatial considerations in neuronal survival signalsNIHNational Institute of Neurological Disorders and Stroke2021$545,358August 15, 2005April 30, 2023SEGAL, ROSALIND A.reporter.nih.gov
Spinal Mechanisms Underlying SCI-Induced Pain: Implications for Targeted TherapyNIHNational Institute of Nursing Research2021$542,043March 21, 2012June 30, 2024DORSEY, SUSAN Greporter.nih.gov
Role of 3D chromatin architecture in axonal regeneration following peripheral nerve injuryNIHNational Institute of Neurological Disorders and Stroke2025$540,322August 1, 2025July 31, 2027PALMISANO, ILARIAreporter.nih.gov
Mechanisms of neuroprotection in diabetic peripheral neuropathyNIHNational Institute of Neurological Disorders and Stroke2021$539,360April 1, 2021March 31, 2022HOKE, AHMETreporter.nih.gov
(PQ9)Mechanistic Role of APE1 and BER in chemotherapy-induced peripheral neuropathyNIHNational Cancer Institute2021$537,592April 1, 2017March 31, 2023KELLEY, MARK R.reporter.nih.gov
Visualizing trigeminal neuralgia at 7 Tesla: Advancing etiological understanding and improving future clinical imaging protocolsNIHNational Institute of Dental & Craniofacial Research2022$532,102September 6, 2022May 31, 2025BALCHANDANI, PRITIreporter.nih.gov
Immune Metabolism of Peripheral Nervous Tissue Degeneration and RegenerationNIHNational Institute of Neurological Disorders and Stroke2025$531,478August 1, 2025July 31, 2030GIGER, ROMAN JENOreporter.nih.gov
Profiling Translation in Nociceptor PlasticityNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$530,647September 15, 2020July 14, 2022CAMPBELL, ZACHARYreporter.nih.gov
Development of a novel survey to screen for chemotherapy-induced peripheral neuropathy in young childrenNIHNational Cancer Institute2024 to 2025$511,478September 1, 2024August 31, 2029RODWIN, ROZALYNreporter.nih.gov
Role of dorsal root ganglion FTO, a RNA demethylase, in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021$509,884July 15, 2019April 30, 2022TAO, YUAN-XIANGreporter.nih.gov
Compromised LDH activity causes motor deficits and hastens ALS progressionNIHNational Institute on Aging2022$503,248July 1, 1996April 30, 2023MILBRANDT, JEFFREY Dreporter.nih.gov
Closed-Loop Micromagnetic Neuromodulation as a Non-Opioid Treatment for Neuropathic Pain.NIHNational Institute of Neurological Disorders and Stroke2021$500,000September 1, 2021August 31, 2023REILLY, THOMASreporter.nih.gov
PNM-CAP: A novel nerve cap to prevent painful neuroma formation in peripheral nerve injuries and amputationsNIHNational Institute of Neurological Disorders and Stroke2025$500,000September 1, 2025August 31, 2026SOLETTI, LORENZOreporter.nih.gov
Restoration of Neuromuscular Function Following Critical Nerve Gap InjuriesNIHNational Institute of Neurological Disorders and Stroke2024$499,999September 19, 2024August 31, 2025SOLETTI, LORENZOreporter.nih.gov
Uncovering astrocyte contributions to neuropathic painNIHNational Institute of Neurological Disorders and Stroke2025$499,979April 15, 2025March 31, 2030NIMMERJAHN, AXELreporter.nih.gov
Parmodulins without Abuse Potential for the Treatment of Neuropathic PainNIHNational Institute of Neurological Disorders and Stroke2025$499,863September 11, 2025August 31, 2027DOCKENDORFF, CHRISTOPHERreporter.nih.gov
Mechanisms of Regeneration: Facial Nerve Injury and RepairNIHNational Institute of Dental & Craniofacial Research2021 to 2023$499,608September 9, 2019August 31, 2024PEPPER, JON-PAULreporter.nih.gov
Charcot-Marie-Tooth Disease Type 2E: Mechanism and therapyNIHNational Institute of Neurological Disorders and Stroke2025$499,452May 15, 2025April 30, 2030BROWN, ANTHONYreporter.nih.gov
Post-translational regulation of opioid and cannabinoid receptorsNIHNational Institute on Drug Abuse2021$498,194April 1, 2017March 31, 2023DEVI, LAKSHMI Areporter.nih.gov
Autoimmune Mechanisms in Peripheral NeuropathyNIHNational Institute of Neurological Disorders and Stroke2021$496,747September 30, 2018August 31, 2023SU, MAUREEN Areporter.nih.gov
Restoration of Muscular Function Following Direct Muscle NeurotizationNIHNational Institute of Neurological Disorders and Stroke2023$494,955September 15, 2023August 31, 2025SOLETTI, LORENZOreporter.nih.gov
Role of a conserved miRNA regulatory axis in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021$492,439July 1, 2018April 30, 2023CATERINA, MICHAEL Jreporter.nih.gov
Neuronal and glial interactions of neuropathic painNIHNational Institute of Dental & Craniofacial Research2021$488,534July 1, 2006March 31, 2023BUCHHEIT, THOMASreporter.nih.gov
Antagonists of CRMP2 Phosphorylation for Chemotherapy-Induced Peripheral NeuropathyNIHNational Institute of Neurological Disorders and Stroke2022$486,793September 15, 2022December 31, 2023KHANNA, RAJESHreporter.nih.gov
Function and Regulation of PMP22 in CMT1A and HNPPNIHNational Institute of Neurological Disorders and Stroke2021 to 2023$481,950September 21, 2021March 31, 2024MOSS, KATHRYN RENAEreporter.nih.gov
Dissecting the Integrated Stress Response in tRNA Synthetase-Associated NeuropathiesNIHNational Institute of Neurological Disorders and Stroke2023 to 2024$481,875March 1, 2023February 28, 2025BURGESS, ROBERT W.reporter.nih.gov
Evaluating the Blood-Brain Barrier Bioavailability and in vivo Efficacy Potential of a Novel TAK1 Inhibitor Targeting Chronic PainNIHNational Institute of Neurological Disorders and Stroke2021$480,955September 8, 2021August 31, 2023SCARNEO, SCOTTreporter.nih.gov
Regenerative Strategies Targeting Retinoic Acid Signaling in Giant Axonal NeuropathyNIHNational Institute of Neurological Disorders and Stroke2025$479,397May 14, 2025April 30, 2030SNIDER, NATASHA Treporter.nih.gov
Function and Regulation of PMP22 in CMT1A and HNPPNIHNational Institute of Neurological Disorders and Stroke2024 to 2025$469,902September 21, 2021March 31, 2027MOSS, KATHRYN RENAEreporter.nih.gov
Discovery of novel openers of the understudied human drug target Kir6.1NIHNational Center for Advancing Translational Sciences2022$466,125September 1, 2022August 31, 2025CARDOZO, TIMOTHY Jreporter.nih.gov
(PQ#9) Promoting Axon Stability to Prevent Therapy-induced Peripheral NeuropathyNIHNational Cancer Institute2021$465,400August 16, 2017July 31, 2022DIANTONIO, AARONreporter.nih.gov
Harnessing T-junction filtering; bidirectional control of sensory neuron impulse trafficNIHNational Institute of Neurological Disorders and Stroke2021$462,331September 15, 2017July 31, 2023HOGAN, QUINN Hreporter.nih.gov
In-vivo Assessment of Neuroinflammation in Painful Trigeminal NeuropathyNIHNational Institute of Dental & Craniofacial Research2023 to 2024$462,000June 1, 2023May 31, 2026LOGGIA, MARCO LUCIANOreporter.nih.gov
Neuroprotection for chemotherapy induced peripheral neuropathyNIHNational Cancer Institute2024$462,000March 1, 2024February 28, 2027YANG, IN HONGreporter.nih.gov
Investigating Peripheral Neuropathy in Spinocerebellar Ataxia Type 3NIHNational Institute of Neurological Disorders and Stroke2025$460,643August 1, 2025July 31, 2030MCLOUGHLIN, HAYLEY Sreporter.nih.gov
Bioengineering a human microphysiological system for elucidation of viral peripheral neurotropism of RSV and SARS-CoV-2NIHNational Institute of Allergy and Infectious Diseases2025$457,778September 5, 2025August 31, 2027MOORE, MICHAEL Jreporter.nih.gov
Discovery of NaV1.7 Inhibitors for the Treatment of PainNIHNational Institute of Neurological Disorders and Stroke2021$455,622May 15, 2021April 30, 2022MULCAHY, JOHN VINCENTreporter.nih.gov
PPAR inhibition of spinal pain transmissionNIHNational Institute of Neurological Disorders and Stroke2021$455,478December 18, 2008January 31, 2024TAYLOR, BRADLEY K.reporter.nih.gov
Discovery and development of novel glycine transporter-2 inhibitors for the treatment of neuropathic painNIHNational Institute on Drug Abuse2022$455,166July 1, 2022June 30, 2025CIOFFI, CHRISTOPHER L.reporter.nih.gov
Mechanisms of Peripheral Nerve Injury and Recovery in a Zebrafish Demyelination ModelNIHNational Institute of Neurological Disorders and Stroke2025$454,424April 1, 2025March 31, 2028PETERSEN, SARAHreporter.nih.gov
Role of Cathepsin S in Dry Eye Associated Neuropathic PainNIHNational Eye Institute2022 to 2023$453,750August 1, 2022July 31, 2025EDMAN, MARIA Creporter.nih.gov
Functional role of satellite glial cells in axon regenerationNIHNational Institute of Neurological Disorders and Stroke2021$453,651December 1, 2019November 30, 2022CAVALLI, VALERIAreporter.nih.gov
Analysis of ascending spinal pain circuitsNIHNational Institute of Neurological Disorders and Stroke2025$453,104February 1, 2025November 30, 2029CHOI, SEUNGWONreporter.nih.gov
Ectopic Olfactory Receptor Guided Facial Nerve RegenerationNIHNational Institute of Dental & Craniofacial Research2023$453,071September 1, 2023August 31, 2025SAKIYAMA-ELBERT, SHELLY ELESEreporter.nih.gov
A Pilot Study to Evaluate the Benefits of Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral NeuropathyNIHNational Cancer Institute2022$452,540September 23, 2022August 31, 2025LEE, RICHARD Treporter.nih.gov
MIXED NOP/MU COMPOUNDS AND THE INVOLVEMENT OF THEIR RECEPTORS IN ANALGESIANIHNational Institute on Drug Abuse2021$452,403July 1, 2018June 30, 2024TOLL, LAWRENCE Rreporter.nih.gov
The impact of ITPR3 mutations on immunityNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$451,000June 21, 2024April 30, 2027VAN OERS, NICOLAI STANISLAS CYRILLEreporter.nih.gov
Diabetic skin influences on outgrowth of human iPSC-derived sensory axonsNIHNational Institute of Neurological Disorders and Stroke2022$450,313July 1, 2022June 30, 2024FARAH, MOHAMED Hreporter.nih.gov
Developing macrophage-based therapies for peripheral nerve injuriesNIHNational Institute of Neurological Disorders and Stroke2023$450,313July 1, 2023June 30, 2025MORRISON, BRETT M.reporter.nih.gov
MAP4K4 inhibition to prevent CIPNNIHNational Institute of Neurological Disorders and Stroke2024$450,313June 21, 2024May 31, 2026HOKE, AHMETreporter.nih.gov
Neuropathic vs. inflammatory pain in chronic pancreatitis: can unique biomarkers be identified to guide mechanistic approaches to pain treatment?NIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$447,525April 1, 2019April 30, 2024SALOMAN, JAMI LYNNreporter.nih.gov
Regulation of Neuroinflammation after Peripheral Nerve InjuryNIHNational Institute of Neurological Disorders and Stroke2023$447,000May 17, 2023April 30, 2026ROOSSIEN, DOUGLAS HOWARDreporter.nih.gov
Genetic and physiological comparison of native human sensory neurons and induced pluripotent stem cells differentiated to sensory neuronsNIHNational Institute of Neurological Disorders and Stroke2022$445,500September 8, 2022August 31, 2025BERTA, TEMUGINreporter.nih.gov
Supplement to Support the Acquisition of a High-Precision 3D PrinterNIHNational Institute of Neurological Disorders and Stroke2025$445,118August 5, 2025November 30, 2025KUMBAR, SANGAMESH GURAPPAreporter.nih.gov
STING & PAIN: exploring a viral signaling protein in nociception and neuropathyNIHNational Institute of Neurological Disorders and Stroke2021$445,031April 15, 2021October 14, 2023BERTA, TEMUGINreporter.nih.gov
Mechanisms of Varicella Zoster Virus Latency in Human Sensory NeuronsNIHNational Institute of Allergy and Infectious Diseases2024 to 2025$444,172January 24, 2024November 30, 2025VENKATESAN, ARUNreporter.nih.gov
Exploring the unknown function of LRRC55 in painNIHNational Institute of Neurological Disorders and Stroke2024$444,125September 19, 2024August 31, 2026YANG, HUANGHEreporter.nih.gov
AIBP and regulation of neuropathic painNIHNational Institute of Neurological Disorders and Stroke2021$443,771August 15, 2017May 31, 2023MILLER, YURYreporter.nih.gov
Characterizing Tissue Specific Regulation of Mutant Lamin Protein DegradationNIHNational Institute on Aging2021$442,936July 1, 2016August 30, 2025HAMMOND, THOMAS MICHAELreporter.nih.gov
The integration of laboratory data with computational 3-D modeling to analyze the role of the central amygdala in neuropathic painNIHNational Institute of Neurological Disorders and Stroke2023$441,500September 7, 2023August 31, 2026MILLER NEILAN, RACHAELreporter.nih.gov
SARM1-mediated mechanisms of axon degenerationNIHNational Institute of Neurological Disorders and Stroke2025$441,195August 1, 2025April 30, 2030FREEMAN, MARC Rreporter.nih.gov
Biomarkers for prognosis of closed-mechanism nerve injuriesNIHNational Institute of Neurological Disorders and Stroke2023$440,604June 1, 2023May 31, 2025MAHAN, MARKreporter.nih.gov
Cholinergic modulation of Descending Pain Control PathwaysNIHNational Institute of Neurological Disorders and Stroke2021$438,712August 1, 2021January 31, 2023MCGEHEE, DANIEL Sreporter.nih.gov
Regulation of microglia-mediated neuroinflammation by store operated Orai1 channelsNIHNational Institute of Neurological Disorders and Stroke2021$438,473April 1, 2021September 30, 2023PRAKRIYA, MURALIreporter.nih.gov
Development of optoelectronically active nerve adhesive for accelerating peripheral nerve repairNIHNational Institute of Neurological Disorders and Stroke2023$437,331September 22, 2023August 31, 2025DUAN, BINreporter.nih.gov
Cellular senescence in chronic pain and agingNIHNational Institute on Aging2022 to 2023$437,254August 1, 2022October 31, 2024TAWFIK, VIVIANNE Lreporter.nih.gov
Targeting TRPV1-containing nerves for radiation-induced pain and oral mucositisNIHNational Institute of Dental & Craniofacial Research2024 to 2025$437,250July 1, 2024June 30, 2026SCHEFF, NICOLE Nreporter.nih.gov
Molecular analysis of the blood-nerve barrier in health and diabetesNIHNational Institute of Neurological Disorders and Stroke2024$437,250September 20, 2024August 31, 2026DANEMAN, RICHARDreporter.nih.gov
The role of a lysosomal mechano-sensitive ion channel in painNIHNational Institute of Neurological Disorders and Stroke2022$435,875September 28, 2022August 31, 2025FEHRENBACHER, JILL Creporter.nih.gov
Targeting the PMP22 Protein to Develop Leads Against Charcot-Marie-Tooth DiseaseNIHNational Institute of Neurological Disorders and Stroke2021 to 2022$435,441January 20, 2021December 31, 2022SANDERS, CHARLES Rreporter.nih.gov
Mechanistic Studies of the Natural Product Nicotinamide Riboside for Relief of Painful Sensory NeuropathyNIHNational Center for Complementary & Integrative Health2021$435,244February 1, 2018July 31, 2022HAMMOND, DONNA Lreporter.nih.gov
Microscopic Robot-Assisted Axon Regrowth for Rapid Repair of Peripheral Nerve InjuriesNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2023$434,868September 1, 2022June 30, 2024MISKIN, MARCreporter.nih.gov
Regulation of Schwann Cell Mitochondria Homeostasis in Painful Peripheral NeuropathyNIHNational Institute of Neurological Disorders and Stroke2023$434,500September 18, 2023August 31, 2025CAMPANA, WENDY M.reporter.nih.gov
Kratom and Cannabinoid Constituents: Mechanisms and Interactive Effects in Neuropathic PainNIHNational Center for Complementary & Integrative Health2023$433,710August 7, 2023July 31, 2025WARD, SARA Jreporter.nih.gov
Near Infrared Light Activated Adhesives for Nerve RepairNIHNational Institute of Biomedical Imaging and Bioengineering2021 to 2022$433,666June 23, 2021April 30, 2024REGE, KAUSHALreporter.nih.gov
Translational profiling of bladder sensory nerves and their cell type identities using dissociation free single nucleus sequencingNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2022$433,125August 1, 2021June 30, 2025JAIN, SANJAYreporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Massachusetts General HospitalBoston, MA16$39.3 million0$0
Johns Hopkins UniversityBaltimore, MD28$28.7 million0$0
Washington UniversitySaint Louis, MO29$25.4 million0$0
Stanford UniversityStanford, CA15$21.8 million0$0
University of TX MD Anderson Can CTRHouston, TX17$18.4 million0$0
University of Texas at DallasRichardson, TX8$18.4 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA20$16.1 million0$0
Boston Children's HospitalBoston, MA5$14.1 million0$0
University of Michigan at Ann ArborAnn Arbor, MI18$13.6 million0$0
Ohio State UniversityColumbus, OH13$12.5 million0$0
University of California, San FranciscoSan Francisco, CA12$12.3 million0$0
Case Western Reserve UniversityCleveland, OH5$12.2 million0$0
Indiana University IndianapolisIndianapolis, IN8$11.7 million0$0
University of RochesterRochester, NY10$11.4 million0$0
New York University School of MedicineNew York, NY5$11.4 million0$0
Duke UniversityDurham, NC8$11.2 million0$0
Marine Biological LaboratoryWoods Hole, MA1$11.2 million0$0
Emory UniversityAtlanta, GA10$10.5 million0$0
Scripps Research Institute, theLa Jolla, CA7$9.6 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX9$9.5 million0$0
University of Maryland BaltimoreBaltimore, MD15$9.4 million0$0
Beth Israel Deaconess Medical CenterBoston, MA3$8.8 million0$0
University of ArizonaTucson, AZ10$8.5 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY8$8.4 million0$0
University of California Los AngelesLos Angeles, CA6$8.3 million0$0
University of PennsylvaniaPhiladelphia, PA8$8.3 million0$0
University of UtahSalt Lake City, UT5$8.2 million0$0
Yale UniversityNew Haven, CT7$8 million0$0
New York UniversityNew York, NY9$8 million0$0
University of California, San DiegoLa Jolla, CA11$8 million0$0
University of IowaIowa City, IA6$7.8 million0$0
Columbia University Health SciencesNew York, NY10$7.6 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA6$7.6 million0$0
Medical College of WisconsinMilwaukee, WI10$7.3 million0$0
Cleveland Clinic Lerner Com-CwruCleveland, OH5$7.3 million0$0
Northwestern University at ChicagoChicago, IL7$7 million0$0
University of Alabama at BirminghamBirmingham, AL5$6.6 million0$0
University of New EnglandBiddeford, ME7$6.6 million0$0
Thomas Jefferson UniversityPhiladelphia, PA4$6.5 million0$0
University of California-IrvineIrvine, CA5$6.2 million0$0
Mayo Clinic RochesterRochester, MN4$6.2 million0$0
University of Vermont & ST Agric CollegeBurlington, VT1$6.1 million0$0
Oregon Health & Science UniversityPortland, OR7$6.1 million0$0
Dana-Farber Cancer InstBoston, MA5$6.1 million0$0
University of Miami School of MedicineCoral Gables, FL6$5.9 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY4$5.9 million0$0
Siteone Therapeutics, Inc.South San Francisco, CA2$5.8 million0$0
University of Texas Med BR GalvestonGalveston, TX5$5.8 million0$0
University of Southern CaliforniaLos Angeles, CA6$5.8 million0$0
University of CincinnatiCincinnati, OH5$5.7 million0$0
Micro-Leads, Inc.Somerville, MA2$5.6 million0$0
4e Therapeutics Inc.Austin, TX1$5.6 million0$0
Jackson LaboratoryBar Harbor, ME7$5.4 million0$0
University of WashingtonSeattle, WA5$5.2 million0$0
University of Georgia Research Foundation IncAthens, GA3$5.1 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ4$5 million0$0
Saint Louis UniversitySaint Louis, MO4$5 million0$0
Baylor College of MedicineHouston, TX3$4.9 million0$0
Harvard Medical SchoolBoston, MA3$4.8 million0$0
Eicosis, LLCDavis, CA1$4.6 million0$0
University of California at DavisDavis, CA4$4.6 million0$0
University of VirginiaCharlottesville, VA6$4.6 million0$0
University of Texas at AustinAustin, TX3$4.5 million0$0
Vanderbilt UniversityNashville, TN5$4 million0$0
Afasci, Inc.Redwood City, CA2$4 million0$0
Mitochondria in Motion, Inc.Saint Louis, MO3$4 million0$0
University of Wisconsin-MadisonMadison, WI6$4 million0$0
Axonova Medical, LLCPhiladelphia, PA3$4 million0$0
University of Nebraska Medical CenterOmaha, NE6$3.8 million0$0
Spaulding Rehabilitation HospitalCharlestown, MA3$3.6 million0$0
Weill Medical Coll of Cornell UnivNew York, NY2$3.6 million0$0
Tufts Medical CenterBoston, MA2$3.5 million0$0
Texas Tech University Health Scis CenterLubbock, TX5$3.5 million0$0
University of MinnesotaMinneapolis, MN6$3.3 million0$0
AnaginIndianapolis, IN1$3.3 million0$0
Visionquest Biomedical INCAlbuquerque, NM3$3.2 million0$0
Navega Therapeutics, Inc.San Diego, CA4$3.2 million0$0
Queen's Medical CenterHonolulu, HI1$3.2 million0$0
Sparian Biosciences, Inc.New York City, NY1$3.1 million0$0
University of Illinois at ChicagoChicago, IL3$3.1 million0$0
University of Missouri-ColumbiaColumbia, MO3$3 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC8$3 million0$0
Albany Medical CollegeAlbany, NY4$3 million0$0
Creative Bio-Peptides, Inc.Potomac, MD1$3 million0$0
Winsantor, Inc.San Diego, CA2$3 million0$0
Kannalife Sciences, Inc.Lloyd Harbor, NY1$3 million0$0
Brown UniversityProvidence, RI2$2.9 million0$0
Albert Einstein College of MedicineBronx, NY3$2.8 million0$0
Wayne State UniversityDetroit, MI4$2.8 million0$0
Raft Pharmaceuticals, LLCSan Diego, CA2$2.7 million0$0
University of Texas HLTH Science CenterSan Antonio, TX5$2.7 million0$0
University of Rhode IslandKingston, RI1$2.7 million0$0
Highland Instruments, Inc.Cambridge, MA3$2.7 million0$0
Apt Therapeutics, Inc.Naperville, IL2$2.7 million0$0
Georgia State UniversityAtlanta, GA3$2.7 million0$0
University of ChicagoChicago, IL3$2.6 million0$0
Auxilium Biotechnologies Inc.San Diego, CA1$2.6 million0$0
Northwestern UniversityChicago, IL2$2.5 million0$0
University of FloridaGainesville, FL5$2.5 million0$0
Boston University Medical CampusBoston, MA4$2.5 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025291$160,321,0500$0
2024306$159,985,8250$0
2023343$187,322,0480$0
2022357$162,938,1300$0
2021342$174,382,0230$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)PA-24-184NIHMay 8, 2027Not listedNotice number printed on 2 awards here
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)PA-24-194NIHMay 7, 2027Not listedNotice number printed on 1 award here
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 1 award here
Functional Target Validation for Alzheimer's Disease-Related DementiasRFA-NS-26-034NIH93.853November 6, 2026Not listedSame assistance listing 93.853 as 387 awards here
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)PAR-27-007NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 387 awards here
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)RFA-NS-26-001NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 387 awards here
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)RFA-NS-26-030NIH93.853November 10, 2026Not listedSame assistance listing 93.853 as 387 awards here
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)PAR-25-369NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 387 awards here
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)PAR-25-371NIH93.853November 18, 2026Not listedSame assistance listing 93.853 as 387 awards here
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)PAR-25-052NIH93.853November 19, 2026Not listedSame assistance listing 93.853 as 387 awards here
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)RFA-AT-25-003NIH93.853November 23, 2026$375,000Same assistance listing 93.853 as 387 awards here
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)RFA-OD-27-008NIH93.853December 2, 2026Not listedSame assistance listing 93.853 as 387 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Required)PAR-24-295NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 387 awards here
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)PAR-24-296NIH93.853December 3, 2026Not listedSame assistance listing 93.853 as 387 awards here
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)RFA-OD-24-011NIH93.853December 4, 2026Not listedSame assistance listing 93.853 as 387 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.853January 7, 2027$375,000Same assistance listing 93.853 as 387 awards here
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)RFA-NS-25-023NIH93.853January 15, 2027$350,000Same assistance listing 93.853 as 387 awards here
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)RFA-DA-28-011NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 387 awards here
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)RFA-DA-28-012NIH93.853January 26, 2027Not listedSame assistance listing 93.853 as 387 awards here
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)PAR-24-268NIH93.853January 27, 2027$500,000Same assistance listing 93.853 as 387 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.