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Data / Research funding / Pediatric Cancer

Pediatric Cancer: 1,837 NIH awards ($2.4B) to 303 organizations

1,837 NIH awards ($2.4B) in the NIH spending category Pediatric Cancer, to 303 organizations, read 2026-11-03. NIH fiscal years 2021 to 2025.

SpecStream is the live web data engine for teams and agents. It reads the NIH and NSF award files each time the agencies update them, and this page is that reading, joined to the open federal funding opportunities on Grants.gov. Ask for the awards you track by topic, organization or state and new awards arrive in your sheet, CRM, Slack or agent as the agencies publish them.

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NIH spending category

Awards

The 500 largest of 1,837 awards in the window.

AwardAgencyInstitute or divisionFiscal yearAmount in windowStartEndPrincipal investigatorSource
COG NCTN Year 12 BIQSFP Progress ReportNIHNational Cancer Institute2021 to 2025$141,250,012April 11, 2014February 28, 2026HAWKINS, DOUGLAS S.reporter.nih.gov
Pediatric HIV/AIDS Cohort Study (PHACS) 2020NIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$71,153,847September 18, 2020July 31, 2026WILLIAMS, PAIGE Lreporter.nih.gov
COG Biospecimen Bank to Support NCI NCTN (U24)NIHNational Cancer Institute2021 to 2025$34,059,058April 22, 2015March 31, 2027RAMIREZ MILAN, NILSA DEL CARMENreporter.nih.gov
Children's Oncology GroupNIHNational Cancer Institute2023 to 2025$31,354,180March 1, 2023February 28, 2026ALONZO, TODD Areporter.nih.gov
Children's Oncology Group NCI Community Oncology Research Program (NCORP) Research Base grantNIHNational Cancer Institute2021 to 2025$27,607,459June 1, 2025July 31, 2026ROTH, MICHAEL E.reporter.nih.gov
Childhood Cancer Survivorship StudyNIHNational Cancer Institute2021 to 2025$27,522,831July 20, 1993November 30, 2026ARMSTRONG, GREGORYreporter.nih.gov
CCSG - Administrative Supplement - ECIANIHNational Cancer Institute2021 to 2025$22,920,176September 1, 1997March 31, 2029ODUNSI, KUNLEreporter.nih.gov
Kids First Pediatric Data Resource CenterNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2022 to 2025$21,614,897September 1, 2025August 31, 2026RESNICK, ADAM CAINreporter.nih.gov
Cancer Center Support GrantNIHNational Cancer Institute2021 to 2025$20,980,807December 1, 1996February 28, 2029MAITRA, ANIRBANreporter.nih.gov
Pediatric Brain Tumor Consortium A multi-institutional consortium devoted to novel phase I and II clinical evaluations of experimental treatment approaches for pediatric CNS tumorsNIHNational Cancer Institute2021 to 2025$18,653,803April 1, 1999March 31, 2026ONAR-THOMAS, ARZUreporter.nih.gov
Tracking and Engaging Disconnected Long-Term Survivors of Childhood Cancer to Improve Adherence to Evidence-Based Screening GuidelinesNIHNational Cancer Institute2021 to 2025$14,573,097September 5, 1997August 31, 2026SWEASY, JOANN B.reporter.nih.gov
Children's Oncology Group Pediatric Early Phase Clinical Trial NetworkNIHNational Cancer Institute2021 to 2024$14,041,303May 3, 2024July 31, 2024WEIGEL, BRENDA J.reporter.nih.gov
NATIONAL CHILDHOOD CANCER REGISTRY (NCCR)NIHNational Cancer Institute2021 to 2025$12,616,798July 1, 2022June 30, 2025KOHLER, BETSYreporter.nih.gov
Center for Live Cell GenomicsNIHNational Human Genome Research Institute2021 to 2025$11,992,289September 15, 2021June 30, 2027HAUSSLER, DAVID Hreporter.nih.gov
(EET Biobank) NCI Early-Phase and Experimental Clinical Trials Biospecimen BankNIHNational Cancer Institute2021 to 2025$11,843,510September 1, 2020March 31, 2027NICOL, KATHLEENreporter.nih.gov
Cancer Center Support (CORE) GrantNIHNational Cancer Institute2021 to 2025$11,628,123August 1, 1997June 30, 2030PALUCKA, ANNA KAROLINAreporter.nih.gov
Cancer Research Consortium of West Michigan (CRCWM)NIHNational Cancer Institute2021 to 2025$11,366,311August 8, 2014July 31, 2026BUTLER, KATHLEEN YOSTreporter.nih.gov
Characterizing pediatric genomes through an optimized sequencing approachNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2024$11,335,114September 23, 2016August 31, 2025GRIMWOOD, JANEreporter.nih.gov
Aurora NCORP Community SiteNIHNational Cancer Institute2021 to 2025$9,617,195August 15, 2014July 31, 2026SAPHNER, THOMAS Jreporter.nih.gov
Kids First Data Resource Center (KFDRC): Harnessing Data-Driven Opportunities in the Present on behalf of the Future of Common Fund Data Ecosystem (CFDE)NIHOffice of the Director, National Institutes of Health2021 to 2025$8,664,754September 25, 2025March 24, 2027RESNICK, ADAM CAINreporter.nih.gov
Clinical Care Gaps and Unmet Needs in Adolescent and Young Adult (AYA) CancersNIHNational Cancer Institute2021 to 2025$8,380,255September 15, 2020June 30, 2027KUSHI, LAWRENCE Hreporter.nih.gov
CCDI SUPPORT FOR NIH/NCI/DCCPS SURVEILLANCE RESEARCH PROGRAMNIHNational Cancer Institute2021 to 2025$8,176,428August 16, 2021August 15, 2026reporter.nih.gov
Comparison of Symptom Burden/Toxicity, Neurocognitive Change, and Functional Outcomes in Pediatric Brain Tumor Patients Treated with Proton vs. Photon Radiotherapy.NIHNational Cancer Institute2021 to 2025$6,769,276March 1, 2021August 31, 2027KAHALLEY, LISA SCHUMreporter.nih.gov
CAUSAL: Cohort to Augment the Understanding of Sarcoma Survivorship Across the LifespanNIHNational Cancer Institute2023 to 2025$6,381,605September 22, 2021August 31, 2027FRIEDMAN, DEBRA L.reporter.nih.gov
Translating genomic discoveries to improved outcomes for high risk acute leukemiaNIHNational Cancer Institute2021 to 2025$6,239,168January 19, 2017August 31, 2030MULLIGHAN, CHARLES Greporter.nih.gov
Metabolic gatekeepers in B-cell malignanciesNIHNational Cancer Institute2021 to 2025$5,936,594April 1, 2016August 31, 2028MÜSCHEN, MARKUSreporter.nih.gov
Pediatric Solid Tumor Microenvironment AtlasNIHNational Cancer Institute2024 to 2025$5,678,350September 1, 2024August 31, 2029ASGHARZADEH, SHAHABreporter.nih.gov
MaineHealth Cancer Care Network (MHCCN) and NCORP Activities across the LifespanNIHNational Cancer Institute2021 to 2025$5,149,103August 13, 2019July 31, 2026REMICK, SCOT Creporter.nih.gov
Survivorship and Access to care for Latinos to Understand and Address health outcome Differences (SALUD)NIHNational Cancer Institute2023 to 2025$5,079,158May 10, 2021April 30, 2027GRAMATGES, MARIA MONICAreporter.nih.gov
Identifying the mechanisms of leukemia progressionNIHNational Cancer Institute2021 to 2025$5,032,279September 22, 2021August 31, 2028CRISPINO, JOHN Dreporter.nih.gov
Puerto Rico NCI Community Oncology Research Program (Puerto Rico NCORP)NIHNational Cancer Institute2021 to 2025$4,943,161August 22, 2014July 31, 2026SANTOS-REYES, LUIS JAVIERreporter.nih.gov
The St. Jude Lifetime CohortNIHNational Cancer Institute2021 to 2024$4,907,509July 9, 2015June 30, 2025HUDSON, MELISSA Mreporter.nih.gov
Mechanistic studies of chromatin modification in transcription regulationNIHNational Institute of General Medical Sciences2021 to 2025$4,727,113February 14, 2019April 30, 2029WOLBERGER, CYNTHIAreporter.nih.gov
Live-cell Activity Architecture in CancerNIHNational Cancer Institute2021 to 2025$4,655,641August 1, 2015July 31, 2029ZHANG, JINreporter.nih.gov
Mutations of Chromatin and its Modifying Machineries in MalignanciesNIHNational Cancer Institute2021 to 2025$4,635,274August 13, 2015August 31, 2029SHILATIFARD, ALIreporter.nih.gov
Proteogenomic characterization of early and late resistance mechanisms in acute myeloid leukemiaNIHNational Cancer Institute2022 to 2025$4,603,890June 15, 2022May 31, 2027TYNER, JEFFREY WALLACEreporter.nih.gov
Chemical Approaches to Modulate PAX3-FOXO1 in Fusion-Positive Alveolar RhabdomyosarcomaNIHNational Cancer Institute2024 to 2025$4,597,865September 6, 2024August 31, 2029KOEHLER, ANGELA NICOLEreporter.nih.gov
Molecular and Cellular Regulation of Pre-Leukemic Stem Cells and their Therapeutic TargetingNIHNational Cancer Institute2021 to 2025$4,594,192September 1, 2021August 31, 2028STEIDL, ULRICHreporter.nih.gov
Molecular Pathogenesis of Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2025$4,591,274August 13, 2015June 30, 2029LEY, TIMOTHY J.reporter.nih.gov
Targeting transcriptional addiction in fusion-driven sarcomaNIHNational Cancer Institute2024 to 2025$4,553,009July 8, 2024June 30, 2029MCFADDEN, DAVID GLENNreporter.nih.gov
Therapeutic Targeting of Human AML Stem CellsNIHNational Cancer Institute2021 to 2025$4,546,001September 8, 2020August 31, 2027JORDAN, CRAIG T.reporter.nih.gov
Texas Pediatric NCORPNIHNational Cancer Institute2021 to 2025$4,510,206August 1, 2014July 31, 2026LANGEVIN, ANNE-MARIE R.reporter.nih.gov
U24-Uncovering the Shared Genetic Origins of Childhood Cancer and Structural Birth Defects Through Enhanced Data Integration and Analysis with the CFDE Data Distillery Knowledge Graph.NIHOffice of the Director, National Institutes of Health2024 to 2025$4,408,884September 19, 2024August 31, 2027TAYLOR, DEANNE MARIEreporter.nih.gov
Pediatric Early Phase Clinical Trials Network (PEP-CTN) Transfer ApplicationNIHNational Cancer Institute2025$4,394,441August 1, 2025July 31, 2029FOX, ELIZABETHreporter.nih.gov
Pediatric Oncology In Vivo Testing Program Coordinating CenterNIHNational Cancer Institute2021 to 2025$4,288,627August 25, 2021June 30, 2026BULT, CAROL Jreporter.nih.gov
Patient Navigation for Improving Transition Success Among Multiply Disadvantaged Young Adult Survivors of Childhood CancerNIHNational Cancer Institute2025$4,236,812September 10, 2025August 31, 2029FREYER, DAVID Rreporter.nih.gov
Translating Pediatric Cancer Proteogenomic Data into Biological and Clinical InsightsNIHNational Cancer Institute2022 to 2025$4,071,173June 1, 2022May 31, 2027ZHANG, BINGreporter.nih.gov
Combining Targeted RIT and Synergistic Novel Agent-RenewalNIHNational Cancer Institute2021 to 2025$3,984,924June 1, 2020May 31, 2027OROZCO, JOHNNIE JOSEreporter.nih.gov
Development of a Universal Assay for Minimal Residual Disease in Acute Myeloid Leukemia using Duplex SequencingNIHNational Cancer Institute2021 to 2025$3,984,664July 16, 2018January 31, 2027BICKEL, KELLIEreporter.nih.gov
NextGen - CRINIHNational Cancer Institute2022 to 2025$3,968,330June 1, 2025May 31, 2026BOLLARD, CATHERINE M.reporter.nih.gov
Discovering mechanisms of neuroblastoma tumorigenesis to improve patient outcomesNIHNational Cancer Institute2021 to 2025$3,932,444September 30, 2017August 31, 2032MARIS, JOHN Mreporter.nih.gov
Prevalence and persistence of the ETV6/RUNX1 pre-leukemic cloneNIHNational Cancer Institute2023 to 2025$3,924,430September 1, 2023August 31, 2028MARCOTTE, ERINreporter.nih.gov
Cooperative Human Tissue NetworkNIHNational Cancer Institute2021 to 2025$3,922,198April 16, 2019March 31, 2029RAMIREZ MILAN, NILSA DEL CARMENreporter.nih.gov
CCL2 and CCR2 as metastatic drivers and therapeutic targets in medulloblastomaNIHNational Cancer Institute2021 to 2025$3,903,008January 1, 2021December 31, 2025WEISS, WILLIAM Areporter.nih.gov
Physician Scientist Training in Clinical OncologyNIHNational Cancer Institute2021 to 2025$3,870,097September 30, 1997June 30, 2030SCHUCHTER, LYNN M.reporter.nih.gov
Elucidating and Targeting tumor dependencies and drug resistance determinants at the single cell levelNIHNational Cancer Institute2022 to 2025$3,840,901September 21, 2022August 31, 2027CALIFANO, ANDREAreporter.nih.gov
In vivo Drug Testing of Pediatric CNS Tumors Using Patient Derived Orthotopic Xenograft ModelsNIHNational Cancer Institute2021 to 2025$3,829,886July 14, 2015June 30, 2026LI, XIAONANreporter.nih.gov
PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAMNIHNational Cancer Institute2021 to 2025$3,805,840July 1, 2002June 30, 2027ALLEN, CARL Ereporter.nih.gov
GEMS: Genomic approach to connecting Elevated germline Mutation rates with male infertility and Somatic healthNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,803,952September 1, 2021May 31, 2027HOTALING, JAMESreporter.nih.gov
Enhance UCSC Xena: extend interactive visualization to ultra-large-scale multi-omics data and integrate with analysis resourcesNIHNational Cancer Institute2021 to 2025$3,765,580September 1, 2021August 31, 2027ZHU, JINGCHUNreporter.nih.gov
Social genomic mechanisms of health disparities among Adolescent and Young Adult (AYA) cancer survivorsNIHNational Cancer Institute2021 to 2025$3,743,381September 10, 2021August 31, 2027ZEBRACK, BRADLEY JAYreporter.nih.gov
Proteogenomic translator for cancer biomarker discovery towards precision medicineNIHNational Cancer Institute2022 to 2025$3,707,896May 1, 2025April 30, 2026WANG, PEIreporter.nih.gov
Characterization of brain dysfunction during development in survivors of childhood acute lymphoblastic leukemiaNIHNational Cancer Institute2021 to 2024$3,657,208March 1, 2020February 28, 2026SUSSMAN, ELYSE Sreporter.nih.gov
Michigan Center for Translational Cancer ProteogenomicsNIHNational Cancer Institute2022 to 2025$3,656,494June 6, 2022May 31, 2027NESVIZHSKII, ALEXEY Ireporter.nih.gov
Nemours NCI Community Oncology Research Program (NCORP)NIHNational Cancer Institute2021 to 2025$3,654,103June 2, 2025July 31, 2026CAYWOOD, EMI Hreporter.nih.gov
Pediatric Preclinical In Vivo Testing Center for Pediatric Sarcoma and Other Solid TumorsNIHNational Cancer Institute2021 to 2025$3,652,183July 1, 2021June 30, 2026KUNG, ANDREW Lreporter.nih.gov
In Vivo Testing of Novel Drug Combinations for Pediatric Soft Tissue SarcomasNIHNational Cancer Institute2021 to 2025$3,632,740July 1, 2021June 30, 2027DYER, MICHAEL Areporter.nih.gov
NGTC - UCLNIHNational Cancer Institute2022 to 2024$3,627,871June 1, 2024May 31, 2025PULE, MARTINreporter.nih.gov
HCMV-induced innate-like CD8 T cells and allogeneic HCT outcomeNIHNational Institute of Allergy and Infectious Diseases2021 to 2025$3,601,018April 9, 2021March 31, 2027HSU, KATHARINE Creporter.nih.gov
Predicting and Preventing Chemotherapy-Induced Cardiotoxicity in African American ChildrenNIHNational Cancer Institute2021 to 2025$3,570,931August 5, 2021July 31, 2026BURRIDGE, PAUL W.reporter.nih.gov
NCI Pediatric In Vivo Testing Program: NeuroblastomaNIHNational Cancer Institute2021 to 2025$3,549,742July 1, 2021June 30, 2027MOSSE, YAEL Preporter.nih.gov
The Florida Pediatric NCORP: NCI Community Oncology Research Program.NIHNational Cancer Institute2021 to 2025$3,543,398June 1, 2025July 31, 2026SALMAN, EMADreporter.nih.gov
SALSA - Study of Active Lifestyle ActivationNIHNational Cancer Institute2021 to 2025$3,527,531September 21, 2021August 31, 2026CHOW, ERIC JESSENreporter.nih.gov
Identifying Relapse Predictors and Therapeutic Vulnerabilities in Ph+ and Ph-like Acute Lymphoblastic LeukemiaNIHNational Cancer Institute2025$3,480,276August 1, 2025July 31, 2029LOH, MIGNON LEE-CHEUNreporter.nih.gov
Intensive tailored exercise training with NAD+ precursor supplementation to improve muscle mass and fitness in adolescent and young adult survivors of hematopoietic stem cell transplantationNIHNational Cancer Institute2021 to 2025$3,469,202September 1, 2021August 31, 2027MOSTOUFI-MOAB, SOGOLreporter.nih.gov
Leveraging Digital Health Solutions to Reduce Learning and Functional Disparities in Children with Cancer - Administrative SupplementNIHNational Cancer Institute2022 to 2025$3,407,172July 5, 2022June 30, 2027PATEL, SUNITA Kreporter.nih.gov
Individual, cultural, and area-based factors associated with survivorship care among Asian/Asian American childhood cancer survivorsNIHNational Cancer Institute2021 to 2025$3,406,825September 6, 2021August 31, 2027MILLER, KIMBERLY ANNreporter.nih.gov
Mitigating Long-term Treatment-related Morbidity in Childhood Cancer SurvivorsNIHNational Cancer Institute2021 to 2024$3,381,151September 1, 2018August 31, 2025BHATIA, SMITAreporter.nih.gov
Development of Potent, Selective, Non-Myelotoxic FLT3 Inhibitors that Retain Efficacy Against Common Mechanisms of ResistanceNIHNational Cancer Institute2021 to 2025$3,350,719December 15, 2020November 30, 2025SHAH, NEIL Preporter.nih.gov
Targeting DKK-1 To Prevent Osteosarcoma MetastasisNIHNational Cancer Institute2021 to 2025$3,331,390July 9, 2021June 30, 2026LOEB, DAVID M.reporter.nih.gov
Career Development in Pediatric and Medical OncologyNIHNational Cancer Institute2021 to 2025$3,314,336September 30, 1997August 31, 2026MESHINCHI, SOHEILreporter.nih.gov
Theranostics for Pediatric Brain CancerNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$3,299,320April 15, 2021January 31, 2027DALDRUP-LINK, HEIKE ELIZABETHreporter.nih.gov
Developing Safe and Effective GD2-CAR T Cell Therapy for Diffuse Midline GliomasNIHNational Cancer Institute2021 to 2025$3,294,656August 6, 2021July 31, 2026MACKALL, CRYSTALreporter.nih.gov
BRidging Information Divides and Gaps to Ensure Survivorship: the BRIDGES Randomized Controlled Trial of a Multilevel Intervention to Improve Adherence to Childhood Cancer SurvivorshipNIHNational Cancer Institute2021 to 2025$3,225,740September 21, 2021August 31, 2027KADAN-LOTTICK, NINA Sreporter.nih.gov
Optimization of a mHealth Physical Activity Promotion Intervention with Mindful Awareness for Adolescent and Young Adult Cancer SurvivorsNIHNational Cancer Institute2021 to 2025$3,207,908September 1, 2021July 31, 2026PHILLIPS, SIOBHAN MARIEreporter.nih.gov
NATIONAL CHILDHOOD CANCER REGISTRY (NCCR) DATA PLATFORMNIHNational Cancer Institute2022$3,205,546September 16, 2022September 15, 2024STOWE, JORDANreporter.nih.gov
Discovery of First-in-class WDR5 PROTACs as a Novel Therapeutic Strategy for MLL-rearranged LeukemiasNIHNational Cancer Institute2022 to 2025$3,200,543May 1, 2022April 30, 2027JIN, JIANreporter.nih.gov
Co-Clinical Research Resource for Imaging Tumor Associated MacrophagesNIHNational Cancer Institute2021 to 2025$3,191,659September 15, 2021August 31, 2026DALDRUP-LINK, HEIKE ELIZABETHreporter.nih.gov
Social Health, Activity Behaviors, and Quality of Life among Young Adult Cancer Survivors: A Longitudinal StudyNIHNational Cancer Institute2021 to 2025$3,178,150March 1, 2021February 28, 2026MILLER, KIMBERLY ANNreporter.nih.gov
Targeting Pediatric Cancer VulnerabilitiesNIHNational Cancer Institute2023 to 2025$3,144,539September 19, 2023August 31, 2030STEGMAIER, KIMBERLYreporter.nih.gov
Psychosocial Risk in Young Survivors of Early Onset Pediatric Cancer: The Role of Physical and Neurocognitive Late EffectsNIHNational Cancer Institute2021 to 2025$3,130,357February 9, 2021January 31, 2027GERHARDT, CYNTHIA Areporter.nih.gov
Lab Research Training in Pediatric Oncology-HematologyNIHNational Cancer Institute2021 to 2025$3,128,223September 30, 1993July 31, 2028FRIEDMAN, ALAN Dreporter.nih.gov
Culturally adapted mobile treatment of chronic pain in adolescent survivors of pediatric bone sarcomaNIHNational Cancer Institute2025$3,128,074September 20, 2022May 31, 2028BRINKMAN, TARA Mreporter.nih.gov
Gvl mHA Specific T Cell Responses Prevent AML Relapse Following Allogeneic Stem Cell Transplantation.NIHNational Cancer Institute2021 to 2025$3,119,515July 1, 2020June 30, 2027VINCENT, BENJAMIN Greporter.nih.gov
Targeting CDK6 expression/activity in Ph+ and Ph1-like acute lymphoblastic leukemia (ALL)NIHNational Cancer Institute2021 to 2025$3,113,868July 1, 2021June 30, 2027CALABRETTA, BRUNOreporter.nih.gov
PROTECT (Harnessing PROTEin degradation for Advanced Childhood Tumors)NIHNational Cancer Institute2024 to 2025$3,108,431May 1, 2024April 30, 2026STEGMAIER, KIMBERLYreporter.nih.gov
Leveraging canine spontaneous cancer to optimize the power of blood biopsyNIHNational Cancer Institute2021 to 2025$3,095,555June 7, 2021May 31, 2027KARLSSON, ELINORreporter.nih.gov
Assessing the effect of virtual navigation interventions to improve health insurance literacy and decrease financial burden: A CCSS randomized trialNIHNational Cancer Institute2022 to 2025$3,070,648June 1, 2022March 31, 2027PARK, ELYSE R.reporter.nih.gov
Predicting Relapse at the Time of Diagnosis in Acute Lymphoblastic LeukemiaNIHNational Cancer Institute2021 to 2025$3,056,754April 1, 2021March 31, 2027DAVIS, KARA LYNNreporter.nih.gov
Dynamic 3D chromatin remodeling in acute leukemia - Resubmission - 1NIHNational Cancer Institute2021 to 2025$3,027,488April 1, 2021June 30, 2026TSIRIGOS, ARISTOTELISreporter.nih.gov
Cancer Immunotherapy Trials Network Central Operations and Statistical CenterNIHNational Cancer Institute2021 to 2022$2,997,769September 22, 2010August 31, 2023DAVIDSON, NANCY ELLENreporter.nih.gov
Adhesion GPCR regulation of acute myeloid leukemia stem cells - Resubmission - 1NIHNational Cancer Institute2021 to 2025$2,988,590March 1, 2021February 28, 2026PARK, CHRISTOPHER Yreporter.nih.gov
NOVOMEDIX TRANSITION TO PHASE II - THERAPEUTICS SBIR CONTRACTSBIR PHASE II - ENHANCED OVERALL SURVIVAL IN HIGH-RISK PEDIATRIC SOLID TUMORS USING A NOVEL ORAL SMALL MOLECULENIHNational Cancer Institute2025$2,977,013September 15, 2025September 14, 2027reporter.nih.gov
Biomarkers of dasatinib response and resistance in T-cell acute lymphoblastic leukemiaNIHNational Cancer Institute2021 to 2025$2,961,810July 1, 2021June 30, 2026YANG, JUN J.reporter.nih.gov
Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication AdherenceNIHNational Cancer Institute2022 to 2025$2,958,176December 15, 2021November 30, 2026BOUCHARD, ELIZABETHreporter.nih.gov
FEN1-Nuclease-Targeted Therapy for Ewing SarcomaNIHNational Cancer Institute2021 to 2025$2,946,641April 1, 2021March 31, 2027KOLODNER, RICHARD Dreporter.nih.gov
Personalized Risk Prediction to Reduce Cardiovascular Disease in Childhood Cancer SurvivorsNIHNational Cancer Institute2022 to 2025$2,933,453July 15, 2022April 30, 2027HOWELL, REBECCA MAUREENreporter.nih.gov
The Evolution of Sarcoma Drug Sensitivity through Time and SpaceNIHNational Cancer Institute2021 to 2024$2,930,546July 1, 2020June 30, 2025SORAGNI, ALICEreporter.nih.gov
Backtracking Leukemia-Typical Somatic Alterations in Cord Blood at Single-cell ResolutionNIHNational Cancer Institute2021 to 2025$2,927,357August 1, 2021July 31, 2026SPECTOR, LOGAN G.reporter.nih.gov
Enhancing B7-H3-CAR T cell therapy for pediatric solid tumorsNIHNational Cancer Institute2022 to 2025$2,924,883March 1, 2022February 28, 2027DERENZO, CHRISTOPHERreporter.nih.gov
Information flow and state transitions at the system and multi-dimensional scales in leukemia progressionNIHNational Cancer Institute2021 to 2024$2,901,922May 1, 2020April 30, 2025ROCKNE, RUSSELL CHRISTIANreporter.nih.gov
Patient-Generated Health Data to Predict Childhood Cancer Survivorship OutcomesNIHNational Cancer Institute2021 to 2025$2,900,455July 5, 2021June 30, 2027HUANG, I-CHANreporter.nih.gov
The synergistic contributions of EBV and malaria to the etiology of Burkitt lymphomaNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$2,895,508December 12, 2019January 31, 2025SAMAYOA REYES, GABRIELA Mreporter.nih.gov
Overcoming metastatic spread of osteosarcoma with RNA loaded nanoparticlesNIHNational Cancer Institute2022 to 2025$2,889,170September 1, 2022August 31, 2027SAYOUR, ELIASreporter.nih.gov
DREAM: Discovering cancer Risks from Environmental contaminants And Maternal/child healthNIHNational Cancer Institute2021 to 2024$2,883,502September 20, 2021August 31, 2025REYNOLDS, PEGGYreporter.nih.gov
Metabolic control of normal and malignant hematopoiesisNIHNational Cancer Institute2021 to 2025$2,869,404September 1, 2020May 31, 2027INTLEKOFER, ANDREW MICHAELreporter.nih.gov
Predictors of Systemic Exposure to Oral 6MP During Maintenance in Adolescentsand Young Adults with Acute Lymphoblastic LeukemiaNIHNational Cancer Institute2021 to 2025$2,864,905March 24, 2021February 28, 2027WOLFSON, JULIE ANNAreporter.nih.gov
A Testing Program to Identify Novel Agents for Treatment of Pediatric and AYA High-Risk Sarcoma, Kidney and Liver CancerNIHNational Cancer Institute2021 to 2025$2,862,121September 1, 2021June 30, 2026KURMASHEVA, RAUSHANreporter.nih.gov
Advanced Imaging Tools to Assess Cancer Therapeutics in PediatricNIHNational Cancer Institute2022 to 2025$2,853,545February 11, 2022June 30, 2027DALDRUP-LINK, HEIKE ELIZABETHreporter.nih.gov
Neoantigen-specific T cell responses for Fibrolamellar Hepatocellular CarcinomaNIHNational Cancer Institute2022 to 2025$2,835,203May 1, 2022April 30, 2027YARCHOAN, MARKreporter.nih.gov
Inducing Neural Maturation in Medulloblastoma by Targeting EZH2NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,801,562September 15, 2022August 31, 2026SNUDERL, MATIJAreporter.nih.gov
Next Generation GPC2-CARs for MedulloblastomaNIHNational Cancer Institute2024 to 2025$2,781,440September 13, 2024August 31, 2026MACKALL, CRYSTALreporter.nih.gov
Clonal Therapy for Pediatric T-cell Acute Lymphoblastic LeukemiaNIHNational Cancer Institute2021 to 2025$2,776,588September 16, 2021August 31, 2026YU, JIYANGreporter.nih.gov
KSHV Latency RegulationNIHNational Institute of Allergy and Infectious Diseases2022 to 2025$2,766,879November 5, 2021October 31, 2026KAYE, KENNETH Mreporter.nih.gov
Base-Edited Hematopoietic Stem and Progenitor Cells To Enable Safe Use Of Highly Potent CD33-Targeted RadioimmunotherapyNIHNational Cancer Institute2022 to 2025$2,758,516July 1, 2022June 30, 2027WALTER, ROLAND BRUNOreporter.nih.gov
Enhancing MAPK-targeted Therapy in PDX Models of BRAF-Mutant Pediatric Brain TumorsNIHNational Cancer Institute2021 to 2025$2,752,745March 8, 2021February 28, 2026BURMA, SANDEEPreporter.nih.gov
Image-guided combination therapies for radiotherapy-induced neurocognitive impairment in pediatric brain tumor survivorsNIHNational Cancer Institute2021 to 2025$2,750,972July 12, 2021June 30, 2027NGEN, ETHEL JOSOreporter.nih.gov
Conformal Total Body and Marrow Irradiation for LeukemiaNIHNational Cancer Institute2021 to 2024$2,727,228September 13, 2011December 31, 2025HUI, SUSANTA Kreporter.nih.gov
Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 MedulloblastomaNIHNational Cancer Institute2022 to 2025$2,726,662April 4, 2011August 31, 2027WECHSLER-REYA, ROBERT J.reporter.nih.gov
Can risk-reducing medications improve breast cancer prevention in childhood and adolescent cancer survivors? Comparative modeling to inform careNIHNational Cancer Institute2022 to 2025$2,726,647September 1, 2022August 31, 2027YEH, JENNIFER M.reporter.nih.gov
The ASPIRES Study: Activating Cancer Survivors and their Primary Care Providers to Increase Colorectal Cancer ScreeningNIHNational Cancer Institute2021 to 2025$2,725,531March 1, 2021March 31, 2025HENDERSON, TARA OLIVEreporter.nih.gov
Bispecific Antibody Therapeutics for Neuroblastoma and Diffuse Midline GliomaNIHNational Cancer Institute2023 to 2025$2,724,833August 1, 2023July 31, 2028OLSON, JAMES Mreporter.nih.gov
Identifying therapeutic pathways targeting medulloblastoma-immune cell interactionsNIHNational Cancer Institute2021 to 2025$2,721,281May 1, 2021April 30, 2027FRAENKEL, ERNESTreporter.nih.gov
EXPLORE AND TARGET THE EPIGENETIC VULNERABILITY OF PAX3-FOXO1-DRIVEN RHABDOMYOSARCOMANIHNational Cancer Institute2022 to 2025$2,717,300July 1, 2022June 30, 2027YANG, JUNreporter.nih.gov
BAF complex deregulation in lymphomaNIHNational Cancer Institute2022 to 2025$2,711,912August 2, 2022July 31, 2027GREEN, MICHAEL RICHARDreporter.nih.gov
Understanding the Increased Risk of Childhood Acute Lymphoblastic Leukemia in LatinosNIHNational Cancer Institute2022 to 2025$2,704,822May 1, 2022April 30, 2026DE SMITH, ADAMreporter.nih.gov
Utility of memantine in preventing cognitive dysfunction in children receiving cranial radiotherapyNIHNational Cancer Institute2022 to 2025$2,688,046September 18, 2019December 31, 2026LAACK, NADIA Nreporter.nih.gov
Targeting Defective DNA Damage Response Pathways in IDH1/2-mutant AMLNIHNational Cancer Institute2022 to 2025$2,684,963February 3, 2022January 31, 2027BINDRA, RANJITreporter.nih.gov
Implementation of an interventional, risk-adapted clinical trial for children with newly diagnosed juvenile myelomonocytic leukemia.NIHNational Cancer Institute2022 to 2025$2,677,641August 1, 2022July 31, 2027STIEGLITZ, ELLIOTreporter.nih.gov
How the 3D Architecture of the Brain Shapes Cancer Cell Fate DecisionsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,670,000September 30, 2021August 31, 2026FILBIN, MARIELLA GRUBERreporter.nih.gov
Sustainability determinants of an intervention to identify clinical deterioration and improve childhood cancer survival in low-resource hospitalsNIHNational Cancer Institute2023 to 2025$2,669,584April 1, 2023March 31, 2028AGULNIK, ASYAreporter.nih.gov
Mechanisms and therapeutic implications of human clonal hematopoiesis (CH) mutationsNIHNational Cancer Institute2022 to 2025$2,657,718June 15, 2022May 31, 2027PAPAPETROU, EIRINIreporter.nih.gov
Generation of tumor specific immunity in canine osteosarcoma through dendritic cell hyperactivationNIHNational Cancer Institute2022 to 2025$2,656,507September 1, 2022August 31, 2027LONDON, CHERYL Areporter.nih.gov
Remodeling the translatome in N-myc mediated medulloblastoma and its therapeutic implicationsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,644,746August 1, 2022July 31, 2027WEISS, WILLIAM Areporter.nih.gov
Promoting Resilience in Early Survivorship among Adolescents and Young Adults with CancerNIHNational Cancer Institute2023 to 2025$2,642,459March 10, 2022February 28, 2027ROSENBERG, ABBY Rreporter.nih.gov
eHealth Intervention for Late Effects of Childhood CancerNIHNational Cancer Institute2021 to 2024$2,636,602September 1, 2019February 28, 2026BRINKMAN, TARA Mreporter.nih.gov
Liquid biopsy approaches to inform neuroblastoma prognosis and disease monitoringNIHNational Cancer Institute2022 to 2025$2,631,965April 11, 2022March 31, 2027APPLEBAUM, MARK ANDREWreporter.nih.gov
Targeting Latency Switch in EBV+ LymphomasNIHNational Cancer Institute2022 to 2025$2,611,281July 1, 2022June 30, 2027ROTH, LISA GIULINOreporter.nih.gov
Personalized neuroblastoma vaccinesNIHNational Cancer Institute2023 to 2025$2,604,046August 1, 2023July 31, 2028MARIS, JOHN Mreporter.nih.gov
Improving Delivery of Genetic Services to High Risk Childhood Cancer Survivors: A Randomized Study of Remote Genetic Services Versus Usual CareNIHNational Cancer Institute2021 to 2024$2,593,712July 8, 2020June 30, 2025HENDERSON, TARA OLIVEreporter.nih.gov
A randomized controlled trial of eSCCIP: An eHealth psychosocial intervention for English and Spanish speaking parents of children with cancerNIHNational Cancer Institute2022 to 2025$2,563,585February 2, 2022January 31, 2027CANTER, KIMBERLYreporter.nih.gov
Membrane protein target for leukemia therapyNIHNational Cancer Institute2021 to 2025$2,553,914September 1, 2020July 31, 2027KANG, XUNLEIreporter.nih.gov
Selectively Targeting Oncogenic NRAS in CancerNIHNational Cancer Institute2021 to 2025$2,550,975April 1, 2015March 31, 2027SHANNON, KEVIN M.reporter.nih.gov
Development of a Phenotype-based Predictive Analytic for Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2025$2,544,479September 15, 2021February 28, 2027SAVONA, MICHAEL Rreporter.nih.gov
Development of Novel PROTACs Targeting the ENL YEATS Domain for Treating MLL-rearranged LeukemiasNIHNational Cancer Institute2021 to 2025$2,540,823April 1, 2021March 31, 2027JIN, JIANreporter.nih.gov
Psychosocial Stress Exacerbates Doxorubicin-induced Cardiovascular AgingNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,538,575April 10, 2020March 31, 2026ZORDOKY, BESHAYreporter.nih.gov
Socioeconomic determinants of childhood cancer outcomes in a large contemporary cohortNIHNational Cancer Institute2022 to 2025$2,536,169February 1, 2022January 31, 2027MARCOTTE, ERINreporter.nih.gov
COG NCTN Integrated Translational Science Center for Hematopoietic Malignancies in ChildrenNIHNational Cancer Institute2022 to 2025$2,523,182March 1, 2022February 28, 2026MESHINCHI, SOHEILreporter.nih.gov
Dissecting innate immune signaling in pre-leukemia evolutionNIHNational Cancer Institute2022 to 2025$2,523,046March 4, 2022February 28, 2027STARCZYNOWSKI, DANIELreporter.nih.gov
Neuronal Regulation of Low-Grade GliomagenesisNIHNational Cancer Institute2022 to 2025$2,518,768April 1, 2022March 31, 2027MONJE-DEISSEROTH, MICHELLEreporter.nih.gov
Targeting the Metabolic Regulator SIRT5 in Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2024$2,518,197July 1, 2020June 30, 2025DEININGER, MICHAEL W.reporter.nih.gov
Dysregulation of Innate Lymphoid Immunity in Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2025$2,498,906September 1, 2021August 31, 2027MUNDY-BOSSE, BETHANYreporter.nih.gov
IL-15 and -21 armored GPC3-specific CAR T cells for children with solid tumorsNIHNational Cancer Institute2022 to 2025$2,490,304January 17, 2022October 31, 2025HECZEY, ANDRAS A.reporter.nih.gov
Prolidase Inhibitors as Therapeutic Agents for Acute Myeloid LeukemiaNIHNational Cancer Institute2022 to 2025$2,488,178March 1, 2022February 28, 2027BACHOVCHIN, DANIELreporter.nih.gov
Social Connectedness in Pediatric Brain Cancer SurvivorsNIHNational Cancer Institute2022 to 2025$2,482,532January 1, 2022June 30, 2027HOCKING, MATTHEW C.reporter.nih.gov
Role of lncRNA mediated R-loops in CTCF boundary function and AML genome organizationNIHNational Cancer Institute2022 to 2025$2,477,191December 3, 2021November 30, 2026HUANG, SUMINGreporter.nih.gov
NCI Pediatric In Vivo Testing Program - LeukemiaNIHNational Cancer Institute2021 to 2025$2,458,093August 1, 2015June 30, 2026LOCK, RICHARD Breporter.nih.gov
MRI-Guided Cryoablation and Imaging-Guided Intratumoral Delivery of STING Agonist Immunotherapy to Target Localized and Metastatic Canine OsteosarcomaNIHNational Cancer Institute2021 to 2024$2,454,927May 1, 2020April 30, 2026KRAITCHMAN, DARA Lreporter.nih.gov
A “STICK” theranostic nanoplatform for image-guided drug delivery to brain malignanciesNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,441,420December 18, 2015May 31, 2026LI, YUANPEIreporter.nih.gov
Machine learning with immunogenetics for the prediction of hematopoietic cell transplant outcomesNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,438,515January 5, 2021December 31, 2025HSU, KATHARINE Creporter.nih.gov
Prodrugs targeting norepinephrine transporter for dual-selective therapy of refractory neuroblastomaNIHNational Cancer Institute2021 to 2024$2,435,800July 1, 2020June 30, 2025CHORNY, MICHAELreporter.nih.gov
Enabling immunotherapy for high-risk Group 3 medulloblastoma via systems immunologyNIHNational Cancer Institute2023 to 2025$2,416,050September 7, 2023August 31, 2028CHI, HONGBOreporter.nih.gov
DISSECTING THE ROLE OF PRDM15 IN NORMAL HEMATOPOIESIS AND B-CELL MALIGNANCIESNIHNational Cancer Institute2021 to 2025$2,407,764December 9, 2020November 30, 2025GUCCIONE, ERNESTOreporter.nih.gov
Liquid biopsy approaches to inform osteosarcoma prognosis and tumor evolutionNIHNational Cancer Institute2021 to 2025$2,405,560July 1, 2025June 30, 2027CROMPTON, BRIANreporter.nih.gov
Tumor-Selective Delivery Approaches for MedulloblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,405,248March 15, 2020December 31, 2024HELLER, DANIEL ALANreporter.nih.gov
Targeting FLT3 for the Treatment of Relapsed or Refractory Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2025$2,401,768July 9, 2021June 30, 2026CALIGIURI, MICHAEL Areporter.nih.gov
The IL-18-IFNγ axis predicts response to immunotherapyNIHNational Cancer Institute2023 to 2025$2,399,099February 1, 2023January 31, 2028GUSTAFSON, HEATHER LEIGH HERDreporter.nih.gov
ABERRANT SIGNALING IN ACUTE MYELOID LEUKEMIANIHNational Cancer Institute2021 to 2025$2,398,924August 22, 2016July 31, 2027KENTSIS, ALEXreporter.nih.gov
ROLE OF RNA SEQUESTRATION IN ACUTE MYELOID LEUKEMIANIHNational Cancer Institute2025$2,398,360August 15, 2025July 31, 2029DI STEFANO, BRUNOreporter.nih.gov
STAG2 modulates environmental toxicant exposures and epigenomic heterogeneityNIHNational Institute of Environmental Health Sciences2022 to 2025$2,388,852March 20, 2022December 31, 2026OHM, JOYCE ELLENreporter.nih.gov
Escape from CAR T surveillance through lineage plasticityNIHNational Cancer Institute2022 to 2025$2,388,454April 1, 2022March 31, 2027ERNST, PATRICIAreporter.nih.gov
Impact of malaria on shaping immunity to EBV in the etiology of Burkitt lymphomaNIHNational Cancer Institute2021 to 2024$2,374,490July 10, 2014June 30, 2025MOORMANN, ANN Mreporter.nih.gov
Cytomegalovirus as an etiologic and clinico-pathogenic factor in childhood acute lymphoblastic leukemiaNIHNational Cancer Institute2022 to 2025$2,371,097June 21, 2022May 31, 2028WIEMELS, JOSEPH LEOreporter.nih.gov
Structural insights into the MLL core complexesNIHNational Cancer Institute2021 to 2024$2,368,181August 25, 2020May 31, 2025DOU, YALIreporter.nih.gov
Probing the activity of DUX4 in FSHDNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$2,367,457March 19, 2010July 31, 2030KYBA, MICHAELreporter.nih.gov
Developing new therapeutic strategies for pediatric tumors that lack clinically actionable mutationsNIHNational Cancer Institute2021 to 2025$2,360,075March 17, 2021May 31, 2026GEELEHER, PAULreporter.nih.gov
Targeting integrated metabolic and epigenetic pathways in childhood ependymomasNIHNational Cancer Institute2022 to 2025$2,359,774July 5, 2022June 30, 2027VENNETI, SRIRAMreporter.nih.gov
Targeting obesity to improve survival from childhood acute lymphoblastic leukemiaNIHNational Cancer Institute2021 to 2025$2,359,104September 14, 2021August 31, 2027ORGEL, ETANreporter.nih.gov
T Cell Regulation of Low-Grade GliomaNIHNational Cancer Institute2022 to 2025$2,353,237September 9, 2022August 31, 2027GUTMANN, DAVID Hreporter.nih.gov
Development of Advanced Preclinical Models for Pediatric Solid TumorsNIHNational Cancer Institute2021 to 2024$2,351,834March 5, 2020February 28, 2025SWEET-CORDERO, ERIC ALEJANDROreporter.nih.gov
Mechanistic and pharmacologic studies of selective mithramycin analogues targeting EWS-FLI1 in Ewing sarcomaNIHNational Cancer Institute2021 to 2024$2,340,398June 1, 2020May 31, 2026TSODIKOV, OLEG Vreporter.nih.gov
Developmental Origin, Injury and Epigenomic Regulation of NF1-Associated Peripheral Nerve Sheath TumorsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,339,120April 15, 2021June 30, 2024ZHU, YUANreporter.nih.gov
Mechanistic Dissection of the BRCA1-SETX-dependent Pathway of R-loop Avoidance and Genome MaintenanceNIHNational Cancer Institute2021 to 2025$2,336,334April 1, 2013June 30, 2027SUNG, PATRICKreporter.nih.gov
Interrogation of the oxidative-stress-induced leukemia program in vivo using metabolic imagingNIHNational Cancer Institute2023 to 2025$2,335,453July 1, 2023June 30, 2028KESHARI, KAYVAN Rreporter.nih.gov
Mechanisms whereby IFN-gamma sensitizes AML to the graft-vs-leukemia effectNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,325,780April 20, 2021March 31, 2026SHLOMCHIK, WARREN Dreporter.nih.gov
Genomics of childhood acute lymphoblastic leukemia in the Childhood Cancer and Leukemia International ConsortiumNIHNational Cancer Institute2022 to 2025$2,325,747August 22, 2022July 31, 2027SPECTOR, LOGAN G.reporter.nih.gov
Immunotherapeutic targeting of gangliosides in Ewing SarcomaNIHNational Cancer Institute2023 to 2025$2,317,710September 19, 2023August 31, 2028MAJZNER, ROBBIE G.reporter.nih.gov
A personalized approach to skin cancer prevention among adolescentsNIHNational Cancer Institute2021 to 2024$2,317,171March 1, 2020February 28, 2026WU, YELENA PINGreporter.nih.gov
Improving risk allocation and developing novel therapies for children with T-ALL and T-LLNIHNational Cancer Institute2023 to 2025$2,310,556May 4, 2015January 31, 2028TEACHEY, DAVID T.reporter.nih.gov
RNA Polymerase II as a Therapeutic Target in Acute Myeloid Leukemia (AML) with RAS Signaling ActivationNIHNational Cancer Institute2022 to 2025$2,310,466July 1, 2022June 30, 2027SMITH, CATHERINE CHOYreporter.nih.gov
Integrated delivery of cancer control interventions for adolescents and young adults living with HIV in ZambiaNIHNational Cancer Institute2023 to 2025$2,294,758September 1, 2023August 31, 2027SUBRAMANIAN, SUJHAreporter.nih.gov
Treatment-Related Cardiotoxicity in Children with Relapsed Acute Myeloid Leukemia - Natural History, Occurrence and ImplicationsNIHNational Heart, Lung, and Blood Institute2022 to 2025$2,291,761July 15, 2022June 30, 2027GETZ, KELLY DIRINGERreporter.nih.gov
Uterine signaling networks in the pathogenesis of pulmonary lymphangioleiomyomatosis (LAM)NIHNational Heart, Lung, and Blood Institute2021 to 2023$2,284,413July 21, 2020June 30, 2025XU, YANreporter.nih.gov
THE ROLE OF SELENOPROTEIN SYNTHESIS PATHWAY IN ACUTE MYELOID LEUKEMIANIHNational Cancer Institute2021 to 2025$2,282,168July 1, 2021June 30, 2027NAKADA, DAISUKEreporter.nih.gov
Uncovering treatment targets for peripheral nerve sheath tumor progression in NF1NIHNational Institute of Neurological Disorders and Stroke2021 to 2024$2,281,119September 1, 2020June 30, 2025LARGAESPADA, DAVID ANDREWreporter.nih.gov
NOURISH-T+: A Randomized Control Trial Targeting Parents in Promoting Healthy Eating and Exercise Behaviors in Pediatric Cancer Survivors with Overweight/ObesityNIHNational Cancer Institute2021 to 2025$2,277,684December 1, 2019November 30, 2026STERN, MARILYNreporter.nih.gov
MYCN drives a ferroptotic vulnerability in neuroblastomaNIHNational Cancer Institute2023 to 2025$2,275,338September 1, 2023August 31, 2026FABER, ANTHONY CHARLESreporter.nih.gov
The role and therapeutic potential of IGF2BP2 in MLL-rearranged leukemiaNIHNational Cancer Institute2022 to 2025$2,254,307March 1, 2022February 28, 2027CHEN, JIANJUNreporter.nih.gov
Chronic Health Conditions in Survivors of Down Syndrome-Associated LeukemiaNIHNational Cancer Institute2022 to 2025$2,251,638June 20, 2022May 31, 2028GRAMATGES, MARIA MONICAreporter.nih.gov
HDO Imaging is a Quantitative Marker of Cerebral Glucose OxidationNIHNational Institute of Biomedical Imaging and Bioengineering2022 to 2025$2,249,123September 1, 2022May 31, 2027MERRITT, MATTHEW Ereporter.nih.gov
Development of ASH1L inhibitors for acute leukemiaNIHNational Cancer Institute2021 to 2024$2,243,021December 1, 2019November 30, 2025GREMBECKA, JOLANTAreporter.nih.gov
Targeting FTO to treat acute myeloid leukemiaNIHNational Cancer Institute2021 to 2024$2,229,526December 1, 2019November 30, 2025CHEN, JIANJUNreporter.nih.gov
PROTECT - Harnessing PROTEin degradation for Advanced Childhood TumorsNIHNational Cancer Institute2024 to 2025$2,221,836May 1, 2024April 30, 2026GRAY, NATHANAEL SCHIANDERreporter.nih.gov
Improving genetically engineered T cells for medulloblastomasNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$2,210,532April 15, 2021April 30, 2026KRENCIUTE, GIEDREreporter.nih.gov
Gammaherpesvirus miRNA suppression of EWSR1 in GC B cell infection and lymphomagenesisNIHNational Cancer Institute2021 to 2025$2,206,513August 1, 2021July 31, 2026TIBBETTS, SCOTT A.reporter.nih.gov
Harnessing the thymus for long-term tumor control with hematopoietic stem cell-derived naive CAR T cellsNIHNational Cancer Institute2022 to 2025$2,202,507March 1, 2022January 31, 2027ZAKRZEWSKI, JOHANNESreporter.nih.gov
Remodeling of 3D chromatin in B cell acute leukemia and its impact on clinical outcomeNIHNational Cancer Institute2021 to 2025$2,201,529April 1, 2021March 31, 2027CARROLL, WILLIAM L.reporter.nih.gov
AML mutation-guided drugging of DNA repairNIHNational Cancer Institute2021 to 2024$2,200,960March 1, 2020January 31, 2026SKORSKI, TOMASZreporter.nih.gov
Improving pediatric brain tumor treatments using FLASH radiotherapyNIHNational Cancer Institute2021 to 2025$2,200,868July 1, 2021June 30, 2027LIMOLI, CHARLESreporter.nih.gov
Humoral immunity after CAR-T cell therapy for B cell malignancies: The HICAR StudyNIHNational Cancer Institute2022 to 2024$2,178,209January 1, 2020December 31, 2025HILL, JOSHUA AIDENreporter.nih.gov
Identification of causal factors underlying cognitive deficits in a mouse model of childhood leukemia survivalNIHNational Institute of Nursing Research2021 to 2024$2,173,427September 7, 2020June 30, 2026REYES, TERESA Mreporter.nih.gov
Targeting an RNA Binding Protein Network in Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2024$2,173,391June 1, 2020May 31, 2025ABDEL-WAHAB, OMARreporter.nih.gov
Genomically informed agent selection and testing in osteosarcoma patient-derived xenograft modelsNIHNational Cancer Institute2021 to 2025$2,164,771July 10, 2015June 30, 2026GORLICK, RICHARD G.reporter.nih.gov
Skin cancer on social media: Analyzing current communications, modeling diffusion potential, and developing innovative prevention-focused messagesNIHNational Cancer Institute2024 to 2025$2,164,376September 3, 2024August 31, 2028WALSH-BUHI, ERIC RICHARDreporter.nih.gov
The role of TRIM37 in driving tumorigenesis and cancer-specific vulnerability to PLK4 inhibitionNIHNational Cancer Institute2022 to 2025$2,153,405June 1, 2022May 31, 2027REGOT, SERGIreporter.nih.gov
Recurrent Tumor-Specific Alternately Processed Transcripts as a Source of Neoantigens for NF1-associated Malignant Peripheral Nerve Sheath Tumor ImmunopreventionNIHNational Cancer Institute2021 to 2023$2,148,196September 25, 2019August 31, 2025LARGAESPADA, DAVID ANDREWreporter.nih.gov
Re-Engaging AYA Survivors in Cancer-Related Healthcare (REACH): A Sequential Multiple Assignment Randomized Trial (SMART)NIHNational Cancer Institute2023 to 2025$2,147,937April 21, 2023March 31, 2028SCHWARTZ, LISA Areporter.nih.gov
Role of PRC1 in RUNX1-ETO-mediated transcriptional controlNIHNational Cancer Institute2021 to 2025$2,144,475July 5, 2021December 31, 2026HODGES, EMILYreporter.nih.gov
Reprogramming myogenic regulatory factors in RMS to promote differentiation and halt growthNIHNational Cancer Institute2023 to 2025$2,136,435May 16, 2023April 30, 2028FORD, HEIDE L.reporter.nih.gov
Patient-Reported Outcomes Version of CTCAE involving Childhood Cancer SurvivorsNIHNational Cancer Institute2021 to 2023$2,133,713August 15, 2019July 31, 2025HUANG, I-CHANreporter.nih.gov
The Role of miR-142 in the Transformation of Clonal Hematopoietic Disorders into AMLNIHNational Cancer Institute2022 to 2025$2,133,556January 1, 2022December 31, 2026MARCUCCI, GUIDOreporter.nih.gov
Genomics of AML PrognosisNIHNational Cancer Institute2021 to 2025$2,130,312April 1, 2008June 30, 2027LAMBA, JATINDER K.reporter.nih.gov
CAUSAL: Cohort to Augment the Understanding of Sarcoma Survivorship Across the LifespanNIHNational Cancer Institute2021 to 2022$2,127,132September 22, 2021August 31, 2023FRIEDMAN, DEBRA L.reporter.nih.gov
Mechanisms of Toxicity Induced by EWS/FLI1 Overdose in Ewing SarcomaNIHNational Cancer Institute2023 to 2025$2,124,600June 7, 2023May 31, 2028STEGMAIER, KIMBERLYreporter.nih.gov
A novel strategy for transcriptional reprogramming of lymphoid leukemia cellsNIHNational Cancer Institute2022 to 2025$2,123,519January 1, 2022December 31, 2026CALABRETTA, BRUNOreporter.nih.gov
mRNA stability and its impact on hematopoiesis and acute leukemiaNIHNational Cancer Institute2022 to 2025$2,122,727January 1, 2022December 31, 2026AIFANTIS, IANNISreporter.nih.gov
Early Identification of Childhood Cancer Survivors at High Risk for Late Onset Cardiomyopathy: An Artificial Intelligence Approach utilizing ElectrocardiographyNIHNational Cancer Institute2022 to 2025$2,122,194April 15, 2022March 31, 2027AKBILGIC, OGUZreporter.nih.gov
Elucidating the SCP4 pathway as a multi-catalytic signaling dependency in acute myeloid leukemiaNIHNational Cancer Institute2023 to 2025$2,121,560August 1, 2023July 31, 2028VAKOC, CHRISTOPHERreporter.nih.gov
Predicting and Monitoring for Cardiac Toxicity in Pediatric AMLNIHNational Heart, Lung, and Blood Institute2023 to 2025$2,120,249August 25, 2023July 31, 2027APLENC, RICHARDreporter.nih.gov
Towards rational design of combination therapeutic targetsNIHNational Cancer Institute2021 to 2024$2,120,092June 1, 2020May 31, 2025TAN, KAIreporter.nih.gov
Quantitative MRI for Pediatric Optic Pathway Glioma Treatment ResponseNIHNational Cancer Institute2022 to 2024$2,119,273June 17, 2020July 31, 2025AVERY, ROBERT ANDREWreporter.nih.gov
Continuous, Non-Invasive Optical Monitoring of Circulating Tumor Cell-Mediated Metastasis in Awake MiceNIHNational Cancer Institute2022 to 2025$2,117,767March 3, 2022February 28, 2027NIEDRE, MARK JONATHANreporter.nih.gov
PolQ as a novel therapeutic target in AMLNIHNational Cancer Institute2021 to 2024$2,115,741January 17, 2020December 31, 2025SKORSKI, TOMASZreporter.nih.gov
Myeloid cell-selective, oligonucleotide-based STAT3 inhibition combined with total marrow and lymphoid irradiation for immunotherapy of acute myeloid leukemiaNIHNational Cancer Institute2023 to 2025$2,114,878July 19, 2023June 30, 2028KORTYLEWSKI, MARCINreporter.nih.gov
Imaging and manipulating oncoprotein phase separation and compartmentalizationNIHNational Cancer Institute2021 to 2025$2,110,885April 1, 2021February 28, 2026SHU, XIAOKUNreporter.nih.gov
The function of Snf5 (SMARCB1), an epigenetic tumor suppressorNIHNational Cancer Institute2021 to 2025$2,106,784July 1, 2005March 31, 2026ROBERTS, CHARLESreporter.nih.gov
Brain-Imaging Markers of Neurotoxicity and Long-Term Outcomes after CAR-T Cell TherapyNIHNational Cancer Institute2023 to 2025$2,106,587April 1, 2023March 31, 2028BANSAL, RAVIreporter.nih.gov
The role of Myeloid cells in pediatric-high grade gliomasNIHNational Cancer Institute2022 to 2025$2,100,261June 1, 2022June 30, 2025HAMBARDZUMYAN, DOLORESreporter.nih.gov
Mapping the Cerebellar Origins of Medulloblastoma SubgroupsNIHNational Cancer Institute2023 to 2025$2,099,734February 16, 2023January 31, 2028NORTHCOTT, PAULreporter.nih.gov
Translational development of osteosarcoma (OS) extracellular vesicle (EV) matrix metalloproteinase (MMP) Activity Assay for assessing patient treatment responsesNIHNational Cancer Institute2025$2,097,875September 1, 2025August 31, 2029TSENG, HSIAN-RONGreporter.nih.gov
Ink4a/ARF/Ink4b locus in Neurofibromatosis Type 1NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,097,360March 1, 2022February 28, 2027DODD, REBECCA Dreporter.nih.gov
Inhibition of Bcl-xL by Targeted DegradationNIHNational Cancer Institute2021 to 2024$2,097,141April 1, 2020March 31, 2026ZHENG, GUANGRONGreporter.nih.gov
Production and progression of premalignant retinoblastoma lesions.NIHNational Cancer Institute2021 to 2025$2,094,221March 1, 2011July 31, 2029COBRINIK, DAVIDreporter.nih.gov
Small molecule mimetics of Humanin that normalize neuronal p-Akt as novel therapeutics for ADNIHNational Institute on Aging2021 to 2023$2,091,868April 1, 2021March 31, 2024JOHN, VARGHESEreporter.nih.gov
Novel combination therapy for AML expressing mutant RUNX1NIHNational Cancer Institute2021 to 2024$2,088,671September 1, 2021August 31, 2025DINARDO, COURTNEYreporter.nih.gov
Defining the Mechanism of Genome Rearrangements in Ph-Like ALL to Determine Predictive Markers in High-Risk Hispanic PopulationsNIHNational Cancer Institute2022 to 2025$2,085,711February 14, 2022January 31, 2027PANNUNZIO, NICHOLASreporter.nih.gov
Early clinical development of a novel IL-7R antibody for treating children with relapsed T-cell leukemiaNIHNational Cancer Institute2022 to 2025$2,084,309April 1, 2022August 31, 2026VARADHACHARY, ATULreporter.nih.gov
Advancing allogeneic CAR-iNKT for the treatment of solid tumors through comparative oncologyNIHNational Cancer Institute2022 to 2025$2,083,891September 1, 2022August 31, 2027MASON, NICOLA Jreporter.nih.gov
Mechanisms and Vulnerabilities of Aberrant Transcriptional Enhancers in CancerNIHNational Cancer Institute2021 to 2022$2,071,954September 1, 2016August 31, 2023LOOK, A. THOMASreporter.nih.gov
Integrating Transforming Approaches to Identify and Target New Vulnerabilities in CancerNIHNational Cancer Institute2021 to 2022$2,071,953August 9, 2016July 31, 2023STEGMAIER, KIMBERLYreporter.nih.gov
EPIGENETIC REPROGRAMMING OF T CELL EXHAUSTION TO ENHANCE TUMOR IMMUNOTHERAPYNIHNational Cancer Institute2021 to 2025$2,070,977March 1, 2020March 31, 2030YOUNGBLOOD, BENJAMIN ALANreporter.nih.gov
Role of FACT in ZFTA-RelA fusion driven ependymomaNIHNational Cancer Institute2023 to 2025$2,070,282April 1, 2023March 31, 2028VENERE, MONICAreporter.nih.gov
New control of oncogene activation in T-cell leukemiaNIHNational Cancer Institute2022 to 2025$2,064,320April 12, 2022March 31, 2027LIANG, CHENGYUreporter.nih.gov
Mechanisms of resistance to ALK inhibitors in ALK-rearranged lymphomaNIHNational Cancer Institute2021 to 2025$2,064,042July 16, 2015November 30, 2026CHIARLE, ROBERTOreporter.nih.gov
A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer SurvivorsNIHNational Cancer Institute2023 to 2025$2,056,218July 8, 2023June 30, 2028HOYT, MICHAEL Areporter.nih.gov
Identifying markers of abnormal neurocognitive trajectories during chemotherapy treatment of childhood acute lymphoblastic leukemiaNIHNational Cancer Institute2022 to 2025$2,055,804September 1, 2022August 31, 2027VAN DER PLAS, ELLENreporter.nih.gov
Dissecting and Targeting RB1-Mutant OsteosarcomaNIHNational Cancer Institute2021 to 2025$2,054,629March 1, 2021February 28, 2027LEE, DUNG-FANGreporter.nih.gov
Targeting tumor and T cell DNA methylomes to improve CAR T cell therapies for diffuse midline gliomaNIHNational Cancer Institute2023 to 2025$2,052,826September 7, 2023August 31, 2028MACK, STEPHEN Creporter.nih.gov
Novel CART Cells for Treating AMLNIHNational Cancer Institute2022 to 2025$2,049,319June 1, 2022May 31, 2027HUA, XIANXINreporter.nih.gov
Map Leukemia-immune Cell Talks with Nanoplasmon Ruler in CAR T-Cell ImmunotherapyNIHNational Cancer Institute2021 to 2024$2,039,396July 1, 2020June 30, 2025CHEN, WEIQIANGreporter.nih.gov
Spatial Control of Myeloid DifferentiationNIHNational Heart, Lung, and Blood Institute2021 to 2024$2,038,767August 15, 2021December 31, 2024LUCAS, DANIELreporter.nih.gov
Isabl GxT: A clinically actionable whole genome and transcriptome precision medicine platformNIHNational Cancer Institute2023 to 2024$2,033,377April 1, 2023March 31, 2026MEDINA, JUAN SANTIAGOreporter.nih.gov
Characterizing the MSI2 network in leukemiaNIHNational Cancer Institute2021 to 2025$2,029,035April 1, 2015November 30, 2025KHARAS, MICHAELreporter.nih.gov
Survivorship and Access to care for Latinos to Understand and address Disparities (SALUD)NIHNational Cancer Institute2021 to 2022$2,026,200May 10, 2021April 30, 2023SCHEURER, MICHAEL E.reporter.nih.gov
Mechanisms of differentiation blockade in CSF3R-mutant AMLNIHNational Cancer Institute2021 to 2025$2,023,612February 5, 2021January 31, 2027MAXSON, JULIA Ereporter.nih.gov
Investigating the IL-1R Pathway in Anaplastic Large Cell Lymphoma for Targeted TherapyNIHNational Cancer Institute2021 to 2025$2,022,453April 6, 2021March 31, 2027YANG, YIBINreporter.nih.gov
TET2-mediated epitranscriptomic regulation in leukemia microenvironmentNIHNational Cancer Institute2023 to 2025$2,018,981September 21, 2023August 31, 2028CHEN, JIANJUNreporter.nih.gov
Mediators Of Arrested Differentiation In Pediatric RhabdomyosarcomaNIHNational Cancer Institute2021 to 2025$2,016,077February 1, 2021January 31, 2027HATLEY, MARK EDWARDreporter.nih.gov
Targeted Small Molecule Inhibitors for Inv(16) LeukemiaNIHNational Cancer Institute2021 to 2023$2,012,862December 1, 2018November 30, 2024BUSHWELLER, JOHN HACKETTreporter.nih.gov
Uncover the role of H3.3-G343R mutation in shaping the DNA damage response, anti-tumor immunity and mechanisms of resistance in glioma.NIHNational Institute of Neurological Disorders and Stroke2022 to 2025$2,006,629January 15, 2022December 31, 2026CASTRO, MARIA Greporter.nih.gov
Central tolerance mechanisms in B-cell malignanciesNIHNational Cancer Institute2021 to 2025$2,003,674June 1, 2011June 30, 2027MÜSCHEN, MARKUSreporter.nih.gov
Explore the signaling mechanisms of acquired resistance to tyrosine kinase inhibitors in AMLNIHNational Cancer Institute2021 to 2025$2,002,562March 3, 2021February 28, 2026HUANG, JIANreporter.nih.gov
Matching panels of in vivo and in vitro model system of pediatric brain tumorsNIHNational Cancer Institute2021 to 2024$2,001,657March 3, 2020February 28, 2026LI, XIAONANreporter.nih.gov
Investigating the role of KAT6A in MLL-rearranged acute myeloid leukemiaNIHNational Cancer Institute2022 to 2025$2,001,625September 1, 2022August 31, 2027BLANCO, MARIO ANDRESreporter.nih.gov
Role of HOTTIP/beta-catenin-HOXA9/PRMT1 axis in hematopoietic and leukemic stem cellsNIHNational Cancer Institute2022 to 2025$2,000,732July 1, 2022June 30, 2027HUANG, SUMINGreporter.nih.gov
Evaluation of the safety and efficacy of non-invasive sonodynamic therapy for diffuse intrinsic pontine gliomaNIHNational Cancer Institute2022 to 2023$2,000,000May 1, 2022August 31, 2024MARCUS, STUARTreporter.nih.gov
AI-based AML risk stratification using next generation cytogenomicsNIHNational Cancer Institute2023 to 2024$2,000,000July 1, 2023June 30, 2025EACKER, STEPHEN MATTHEWreporter.nih.gov
Simultaneous pharmacological profiling of oncogenic gene fusion proteins in cancerNIHNational Cancer Institute2023 to 2024$2,000,000July 1, 2023June 30, 2025FEDERATION, ALEXANDERreporter.nih.gov
A Phase 1b, Open-Label, Study of a Novel Targeted Radiotherapy in Children, Adolescents and Young Adults with Inoperable Relapsed or Refractory High Grade GliomaNIHNational Cancer Institute2022 to 2023$1,999,998September 16, 2022June 30, 2024REILLY, LAURENCEreporter.nih.gov
TOPIC 414 : SYNTHETIC BIOLOGY GENE CIRCUITS FOR CANCER THERAPYNIHNational Cancer Institute2021$1,999,993August 1, 2021July 31, 2023LEE, GARYreporter.nih.gov
Dual-targeting allogeneic CAR T-cells for universal therapy of T-cell malignanciesNIHNational Cancer Institute2024 to 2025$1,999,703September 1, 2024August 31, 2027HEIN, SARAH MARIEreporter.nih.gov
GENETICALLY ENGINEERED T CELLS FOR DIPGNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,999,395August 1, 2022July 31, 2027KRENCIUTE, GIEDREreporter.nih.gov
Ceraxa (Ceramide NanoLiposome) and Vinblastine For the Improved Treatment of Relapsed or Refractory Acute Myeloid LeukemiaNIHNational Cancer Institute2022 to 2023$1,999,256September 14, 2022August 31, 2025ADAIR, BERNADETTE MCMAHONreporter.nih.gov
Vascular Remodeling in the Bone Marrow Leukemic Niche: A Therapeutic Target?NIHNational Cancer Institute2021 to 2024$1,996,349April 1, 2020March 31, 2026MARCUCCI, GUIDOreporter.nih.gov
Transporters and MedulloblastomaNIHNational Cancer Institute2021 to 2025$1,995,922April 1, 2015November 30, 2026SCHUETZ, JOHN Dreporter.nih.gov
Integrated Systems Biology of Pediatric AMLNIHNational Cancer Institute2023 to 2025$1,995,809December 15, 2022November 30, 2027LAMBA, JATINDER K.reporter.nih.gov
Phase 2 clinical trial of a novel T cell therapy following bridging therapy with hypomethylating agents for relapsed AML patients post-stem cell transplantNIHNational Cancer Institute2023 to 2025$1,994,514August 10, 2023July 31, 2026VERA, JUAN FERNANDOreporter.nih.gov
Engineering an immuno-isolating hydrogel for restoring ovarian endocrine functionNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,991,992September 30, 2016February 28, 2026SHIKANOV, ARIELLAreporter.nih.gov
Biomarkers of Vision Loss in Children with Optic Pathway GliomasNIHNational Eye Institute2021 to 2023$1,991,559March 1, 2019February 28, 2025AVERY, ROBERT ANDREWreporter.nih.gov
Multisite Implementation of COMPRENDO (ChildhOod Malignancy Peer REsearch NavigatiOn) to improve participation of Hispanic children in cancer clinical trialsNIHNational Cancer Institute2023 to 2025$1,990,997July 26, 2023June 30, 2028ARISTIZABAL, PAULAreporter.nih.gov
Development of an immunomodulating peptide as a therapy for osteosarcoma in canine and humanNIHNational Cancer Institute2023 to 2024$1,990,199September 19, 2023August 31, 2025ALFARO, JOSHUAreporter.nih.gov
Targeting vulnerabilities of PPM1D-mutant gliomasNIHNational Cancer Institute2021 to 2025$1,989,782February 1, 2021January 31, 2026BANDOPADHAYAY, PRATITIreporter.nih.gov
Novel Therapeutic Approaches for the Treatment of NeuroblastomaNIHNational Cancer Institute2021 to 2024$1,988,123April 1, 2020March 31, 2026DYER, MICHAEL Areporter.nih.gov
The role of the cohesin complex in hematopoietic transformation and leukemia maintenanceNIHNational Cancer Institute2023 to 2025$1,987,941September 19, 2023August 31, 2028VINY, AARON Dreporter.nih.gov
Identification of Novel Pathways Causing NF1-Driven Schwann Cell TumorsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,987,528December 1, 2021November 30, 2026RATNER, NANCYreporter.nih.gov
Mechanisms and targeting of aberrant Gas activation in myeloid neoplasmsNIHNational Cancer Institute2023 to 2025$1,986,303April 1, 2023March 31, 2028PAPAPETROU, EIRINIreporter.nih.gov
Digital Self-Management and Peer Mentoring Intervention to Improve the Transition from Pediatric to Adult Health Care for Childhood Cancer SurvivorsNIHNational Cancer Institute2023 to 2025$1,984,223July 1, 2023June 30, 2028DEVINE, KATIE Areporter.nih.gov
Targeting Syk to enhance anti-tumor immune responses in neuroblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,981,973August 1, 2021April 30, 2026JOSHI, SHWETAreporter.nih.gov
Defining epigenetic mechanisms in NPM1c mutant leukemiaNIHNational Cancer Institute2021 to 2025$1,981,710April 9, 2021March 31, 2027ARMSTRONG, SCOTT Areporter.nih.gov
AF9(MLLT3) Function in Leukemia and Normal HematopoiesisNIHNational Cancer Institute2021 to 2023$1,980,668July 1, 2019June 30, 2025BUSHWELLER, JOHN HACKETTreporter.nih.gov
Delirium in Children Undergoing Hematopoietic Stem Cell TransplantsNIHNational Cancer Institute2021 to 2024$1,975,976September 1, 2020May 31, 2026TRAUBE, CHANIreporter.nih.gov
Measuring Perceptions of Utility of Clinical Genome Sequencing: Instrument Testing and ValidationNIHNational Human Genome Research Institute2021$1,974,475December 5, 2011May 31, 2023PLON, SHARON E.reporter.nih.gov
Mechanistic biomarkers to enable Bcl2 inhibitor therapies for neuroblastomaNIHNational Cancer Institute2021 to 2025$1,974,115February 18, 2021January 31, 2026HOGARTY, MICHAEL Dreporter.nih.gov
Elucidating the role of the noncoding genome in neuroblastomaNIHNational Cancer Institute2021 to 2025$1,973,426March 12, 2021February 28, 2027DISKIN, SHARONreporter.nih.gov
A novel approach for treating myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML)NIHNational Cancer Institute2024 to 2025$1,972,824September 9, 2024August 31, 2026FAN, XIAOMINreporter.nih.gov
Bioethics research to understand engagement in decision-making among adolescents and young adults with cancer at risk for health care disparitiesNIHNational Cancer Institute2023 to 2025$1,967,607September 1, 2025August 31, 2026MACK, JENNIFER Wreporter.nih.gov
Towards an inclusive genomic risk classification for acute myeloid leukemia (AML)NIHNational Cancer Institute2023 to 2025$1,961,587September 18, 2023July 31, 2028EISFELD, ANN-KATHRINreporter.nih.gov
End-of-life care quality for adolescents and young adults with cancer: Including the patient voice in quality assessmentNIHNational Cancer Institute2021 to 2025$1,960,563February 13, 2018December 31, 2029MACK, JENNIFER Wreporter.nih.gov
Toward Translation of an Immunotherapeutic Nanomedicine for NeuroblastomaNIHNational Cancer Institute2022 to 2025$1,952,176July 1, 2022June 30, 2027WILSON, JOHN TANNERreporter.nih.gov
Image-guided dosimetry-based alpha particle therapy for neuroblastoma.NIHNational Cancer Institute2022 to 2023$1,951,675August 4, 2022July 31, 2025SCHULTZ, MICHAEL KINGreporter.nih.gov
Overcoming Resistance Mechanisms in Hedgehog and Myc-amplified MedulloblastomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,949,505December 1, 2020November 30, 2025MAHATO, RAM I.reporter.nih.gov
First-in-class ETS inhibitor TK216: Translational Biology and Oral Dosage Form DevelopmentNIHNational Cancer Institute2021 to 2022$1,948,791September 1, 2021August 31, 2024KRISHNAN, RAJESHreporter.nih.gov
Modulating the PD-1/PD-L1 checkpoint to promote antitumor activity of HER2 CAR T cells in patients with sarcomaNIHNational Cancer Institute2023 to 2025$1,938,900March 7, 2023February 29, 2028HEGDE, MEENAKSHI Greporter.nih.gov
The role of ATRX mutation in the epigenetic dysregulation of cell cycle in pediatric high-grade gliomaNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,938,300July 1, 2021June 30, 2026KOSCHMANN, CARL Jreporter.nih.gov
A Randomized Trial of a Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer SurvivorsNIHNational Cancer Institute2021 to 2023$1,926,339September 19, 2019August 31, 2025KADAN-LOTTICK, NINA Sreporter.nih.gov
Engineering 3D Osteosarcoma Models to Elucidate Biology and Inform Drug DiscoveryNIHNational Cancer Institute2023 to 2025$1,924,041April 1, 2023March 31, 2028YANG, FANreporter.nih.gov
Therapeutic degradation of Capicua (CIC) fused oncoproteins in undifferentiated sarcomasNIHNational Cancer Institute2021 to 2025$1,922,391June 17, 2021May 31, 2026OKIMOTO, ROSSreporter.nih.gov
Derivation of Functional Spermatogonia Stem Cells from Rhesus Macaque iPSCsNIHOffice of the Director, National Institutes of Health2021 to 2022$1,921,633September 9, 2019June 30, 2024EASLEY, CHARLES A.reporter.nih.gov
Large scale single-cell gene rearrangement detection with a microfluidic deviceNIHNational Cancer Institute2021 to 2025$1,921,615July 1, 2020June 30, 2027ZHONG, JOHNreporter.nih.gov
Preclinical-Clinical Trials Collaboration to effectively advance new combination therapies for malignant peripheral nerve sheath tumorsNIHNational Cancer Institute2022 to 2025$1,921,213July 8, 2022June 30, 2027CICHOWSKI, KAREN Mreporter.nih.gov
Therapeutic strategies for treatment of giant congenital melanocytic neviNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,921,106August 1, 2017July 31, 2028FISHER, DAVID Ereporter.nih.gov
Bright IDEAS-Young Adults: Problem-Solving Skills Training to Reduce Distress among Young Adults with CancerNIHNational Cancer Institute2023 to 2025$1,919,850April 15, 2020March 31, 2027DEVINE, KATIE Areporter.nih.gov
Improving Patient-Important Outcomes with Testosterone Replacement in Hypogonadal Men with a Prior History of CancerNIHNational Cancer Institute2022 to 2025$1,917,613May 8, 2019April 30, 2027GARCIA, JOSE M.reporter.nih.gov
Investigation of ecDNA as a driver of intratumoral heterogeneity and treatment resistance in high-risk medulloblastomaNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,914,963September 1, 2023August 31, 2028CHAVEZ, LUKASreporter.nih.gov
HPV, HIV and Oral Microbiota Interplay in Nigerian Youth (HOMINY)NIHNational Institute of Dental & Craniofacial Research2024 to 2025$1,910,616August 1, 2024July 31, 2027COKER, MODUPEreporter.nih.gov
Mechanism of Therapy in high-risk AMLNIHNational Cancer Institute2021 to 2024$1,909,701July 1, 2020June 30, 2025AZAM, MOHAMMADreporter.nih.gov
MICROFABRICATED INSTRUMENTATION TO MEASURE SPHINGOLIPID SIGNALING IN HUMAN ACUTE MYELOID LEUKEMIANIHNational Cancer Institute2021 to 2023$1,909,270May 7, 2019April 30, 2025ALLBRITTON, NANCY L.reporter.nih.gov
Exposure to per- and polyfluoroalkyl substances (PFAS) and risk of cancer in childrenNIHNational Institute of Environmental Health Sciences2021 to 2023$1,909,233September 3, 2021August 31, 2025METAYER, CATHERINEreporter.nih.gov
The Role of HIF1A-DNMT3A axis in AML1/ETO-Driven Acute MyelogenousLeukemiaNIHNational Cancer Institute2023 to 2025$1,908,225December 7, 2020November 30, 2026LIU, SHUJUNreporter.nih.gov
Evaluating environmental metals exposure on risk of LCHNIHNational Cancer Institute2021 to 2023$1,903,519August 1, 2019July 31, 2025SCHEURER, MICHAEL E.reporter.nih.gov
Lipid nanomedicine targeting multiple signaling pathways of medulloblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,901,424July 15, 2022May 31, 2027MAHATO, RAM I.reporter.nih.gov
Project Milestones: Young Adult Cancer SurvivorshipNIHNational Cancer Institute2021 to 2024$1,898,106May 4, 2021December 31, 2025MILAM, JOEL Ereporter.nih.gov
Regulation of FLT3 Signaling in LeukemiaNIHNational Cancer Institute2023 to 2025$1,897,988September 1, 2023August 31, 2028TONG, WEIreporter.nih.gov
The role of DNAJB1-PKAc-β-catenin axis in fibrolamellar HCCNIHNational Cancer Institute2023 to 2025$1,896,102April 1, 2023March 31, 2028TIMCHENKO, NIKOLAI A.reporter.nih.gov
Mdm2 Alternative Splicing in DNA Damage and CancerNIHNational Cancer Institute2021 to 2024$1,893,675September 1, 2021August 31, 2026CHANDLER, DAWN Sreporter.nih.gov
Using Tailored mHealth Strategies to Promote Weight Management among Adolescent and Young Adult Cancer SurvivorsNIHNational Cancer Institute2023 to 2025$1,883,659April 1, 2023March 31, 2028VALLE, CARMINA Greporter.nih.gov
A Systems Epidemiology Approach for Predicting Methotrexate Neurotoxicity in Pediatric Acute LeukemiaNIHNational Cancer Institute2023 to 2025$1,882,395April 21, 2023March 31, 2028BROWN, AUSTIN Lreporter.nih.gov
Developmental regulation of apoptosis as a modifiable driver of radiotherapy-induced neurocognitive impairment in pediatric patientsNIHNational Cancer Institute2021 to 2025$1,878,585March 9, 2020February 28, 2027SAROSIEK, KRISTOPHER ANDREWreporter.nih.gov
Transcriptional Regulation in ZFTA-RELA EpendymomaNIHNational Cancer Institute2023 to 2025$1,877,375August 1, 2023July 31, 2028MACK, STEPHEN Creporter.nih.gov
Targeting Menin in Acute Leukemia with Upregulated HOX GenesNIHNational Cancer Institute2023 to 2025$1,868,714May 1, 2023April 30, 2028GREMBECKA, JOLANTAreporter.nih.gov
Research Training in Pediatric OncologyNIHNational Cancer Institute2021 to 2024$1,864,901July 13, 2009June 30, 2025ARMSTRONG, SCOTT Areporter.nih.gov
Targeting cooperative mechanisms of metastatic colonization in osteosarcomaNIHNational Cancer Institute2022 to 2025$1,864,638July 6, 2022June 30, 2027ROBERTS, RYAN D.reporter.nih.gov
Next Generation Immunotherapies for Pediatric CancersNIHNational Cancer Institute2024 to 2025$1,863,847September 9, 2024August 31, 2031MACKALL, CRYSTALreporter.nih.gov
3-Dimensional Retinal Organoid Platform for the Study of RetinoblastomaNIHNational Cancer Institute2021 to 2024$1,863,510September 15, 2020June 30, 2025PELAEZ, DANIELreporter.nih.gov
Exercise as an Immune Adjuvant for Gamma Delta T-cell Therapies in Hematologic MalignanciesNIHNational Cancer Institute2023 to 2025$1,860,326April 1, 2023March 31, 2028SIMPSON, RICHARD Jreporter.nih.gov
Transcription factors in kidney developmentNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2025$1,856,383August 15, 2003December 31, 2027XU, PIN-XIANreporter.nih.gov
Tumor 'tractor beam' for diffuse cancersNIHNational Cancer Institute2021 to 2025$1,854,880September 23, 2021August 31, 2026MOKARRAM-DORRI, NASSIRreporter.nih.gov
Mechanisms and small-molecule targeting of SWI/SNF activity in neuroblastomaNIHNational Cancer Institute2022 to 2025$1,853,581July 18, 2022June 30, 2027HODGES, HAMILTON COURTNEYreporter.nih.gov
Molecular Mechanism of Leukemogenesis involving AML1-ETONIHNational Cancer Institute2021 to 2025$1,849,687July 16, 2004March 31, 2027ZHANG, DONG-ERreporter.nih.gov
SMARCB1 regulated SWI/SNF complex function in Malignant Rhabdoid TumorsNIHNational Cancer Institute2021 to 2025$1,849,490April 1, 2021March 31, 2027WANG, XIAOFENGreporter.nih.gov
Modeling BRAF-fusion driven pediatric brain tumors in the mouseNIHNational Cancer Institute2021 to 2023$1,848,656June 1, 2019May 31, 2024VENTURA, ANDREAreporter.nih.gov
Evaluation of a telehealth oncofertility care intervention in adolescent and young adult cancer patients: a stepped wedge cluster randomized controlled trialNIHNational Cancer Institute2023 to 2025$1,843,991December 1, 2022November 30, 2027SU, HUI-CHUN IRENEreporter.nih.gov
An Integrative Approach to Evaluate Neurocognitive Disparities in Latinos Undergoing Treatment for Childhood Leukemia.NIHNational Cancer Institute2022 to 2025$1,843,835July 1, 2022June 30, 2028RAGHUBAR, KIMBERLY PAULINEreporter.nih.gov
Targeting PRC1 in leukemiaNIHNational Cancer Institute2023 to 2025$1,843,693September 1, 2023August 31, 2028CIERPICKI, TOMASZreporter.nih.gov
Measuring Lifelong Multimorbidity with Patient Perspectives: Implementing and Visualizing the Cumulative Burden Methodology Across CohortsNIHNational Cancer Institute2022 to 2025$1,843,355March 11, 2022February 28, 2026BHAKTA, NICKHILL HITESHreporter.nih.gov
Robust assays to define telomere maintenance mechanisms as cancer biomarkers.NIHNational Cancer Institute2021 to 2025$1,833,412September 16, 2021August 31, 2027REYNOLDS, CHARLES PATRICKreporter.nih.gov
CAR NKT Cell Immunotherapy of NeuroblastomaNIHNational Cancer Institute2021 to 2025$1,828,377June 12, 2021May 31, 2026METELITSA, LEONID Sreporter.nih.gov
An augmented reality platform to reduce post-operative and chronic opioid use in pediatric cancerNIHNational Institute on Drug Abuse2021 to 2022$1,828,326June 1, 2020August 31, 2024YORK, CHRISTINAreporter.nih.gov
Attacking the Immunopeptidome of Ewing SarcomaNIHNational Cancer Institute2023 to 2025$1,827,865September 11, 2023July 31, 2028MACKALL, CRYSTALreporter.nih.gov
Phase 0/1 trial of ONC206 - a novel imipridone for children with diffuse midline gliomas and recurrent malignant brain tumorsNIHNational Cancer Institute2022 to 2025$1,826,791September 7, 2022August 31, 2028MUELLER, SABINEreporter.nih.gov
Research Training in Childhood CancerNIHNational Cancer Institute2021 to 2025$1,823,127July 1, 2007August 31, 2027SWEET-CORDERO, ERIC ALEJANDROreporter.nih.gov
Development of a generalizable chemo-proteomics screening platform for small molecule degraders applied to HDACsNIHNational Cancer Institute2022 to 2025$1,822,992June 7, 2022April 30, 2026FISCHER, ERIC SEBASTIANreporter.nih.gov
A Randomized Controlled Trial using a Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults with CancerNIHNational Cancer Institute2023 to 2025$1,822,032June 9, 2023May 31, 2027ELSWICK, RONALD K.reporter.nih.gov
Tumor-derived extracellular vesicles in the pre-metastatic niche.NIHNational Cancer Institute2021 to 2025$1,821,912August 1, 2017August 31, 2029DECLERCK, YVES Areporter.nih.gov
Evaluating ADGRB3 as a tumor suppressor epigenetically silenced in WNT medulloblastomaNIHNational Cancer Institute2021 to 2024$1,815,797September 1, 2019January 31, 2025VAN MEIR, ERWIN G.reporter.nih.gov
METABOLIC REGULATION IN LEUKEMIA-INITIATING CELLSNIHNational Cancer Institute2021 to 2024$1,806,031April 1, 2015June 30, 2025NAKADA, DAISUKEreporter.nih.gov
An Integrated Biochemical and Structural Approach to Delineating the Biology of EWSR1NIHNational Institute of General Medical Sciences2021 to 2025$1,805,092September 30, 2021June 30, 2026LIBICH, DAVID STEVENreporter.nih.gov
Analysis of E-selectin Ligands of Human Acute Leukemia Cells and their Biology in LeukemogenesisNIHNational Cancer Institute2021 to 2023$1,799,538July 17, 2019June 30, 2025SACKSTEIN, ROBERTreporter.nih.gov
Symptom Screening Linked to Care Pathways for Children with Cancer: a Cluster Randomized TrialNIHNational Cancer Institute2021 to 2024$1,797,779August 1, 2020April 30, 2025SUNG, LILLIANreporter.nih.gov
Trispecific CAR-T cells targeting CD19, CD20 and CD22 to treat B-cell malignanciesNIHNational Cancer Institute2023 to 2025$1,797,355July 21, 2023June 30, 2028VASU, SUMITHIRAreporter.nih.gov
Targeting GSK3B in refractory B-cell malignanciesNIHNational Cancer Institute2023 to 2025$1,794,818July 19, 2023June 30, 2028MÜSCHEN, MARKUSreporter.nih.gov
VLA-4–targeted 67Cu-LLP2A preconditioning enhances efficacy of T-cell-based adoptive immunotherapyNIHNational Cancer Institute2023 to 2025$1,788,311July 5, 2023June 30, 2028PATEL, RAVI BHASKERreporter.nih.gov
Cause and therapeutic impact of DNA-protein crosslink repair defect in myeloid leukemiasNIHNational Cancer Institute2021 to 2025$1,785,830July 1, 2021June 30, 2026KAUFMANN, SCOTT Hreporter.nih.gov
Evaluation of the Communication Plan Early through End-of-Life (COMPLETE) InterventionNIHNational Cancer Institute2021 to 2024$1,785,128August 13, 2019July 31, 2025PERKINS, SUSAN M.reporter.nih.gov
Ameliorating off-target toxicities of CAR T cells by engineering NOT gatesNIHNational Cancer Institute2022 to 2025$1,777,692August 1, 2022July 31, 2027LIM, WENDELL Areporter.nih.gov
NextGen - CHOPNIHNational Cancer Institute2022 to 2025$1,775,451June 1, 2025May 31, 2026MARIS, JOHN Mreporter.nih.gov
Leveraging the TCR Repertoire to identify target neoantigens in FLT3-ITD positive Acute Myeloid LeukemiaNIHNational Cancer Institute2021 to 2025$1,769,974June 1, 2021May 31, 2027ALACHKAR, HOUDAreporter.nih.gov
Molecular Pathogenesis of AF10-Rearranged LeukemiasNIHNational Cancer Institute2022 to 2025$1,767,803April 12, 2022March 31, 2027DESHPANDE, ANIRUDDHA J.reporter.nih.gov
Oncogenic Drivers of Rhabdomyosarcoma Cell State, Cancer Stem Cells and MetastasisNIHNational Cancer Institute2023 to 2025$1,766,080May 1, 2023April 30, 2028LANGENAU, DAVID MICHAELreporter.nih.gov
PennPET Explorer Scanner With Scalable Axial Length for Total Body PET ImagingNIHNational Cancer Institute2021 to 2023$1,763,850December 5, 2018November 30, 2023KARP, JOEL Sreporter.nih.gov
Targeting EWS-ATF1 Fusion in Clear Cell Sarcoma of Soft TissueNIHNational Cancer Institute2022 to 2025$1,757,804December 1, 2021November 30, 2026LI, BINGBINGreporter.nih.gov
Phase I/II clinical trial of HDAC inhibition for GVHD prevention in children, adolescents, and young adultsNIHNational Cancer Institute2021 to 2024$1,755,671June 1, 2020May 31, 2026CHOI, SUNG WONreporter.nih.gov
Targeting Microenvironmental Signals in Myeloid MalignanciesNIHNational Cancer Institute2022 to 2025$1,754,424July 1, 2022June 30, 2027BAJAJ, JEEVISHAreporter.nih.gov
Principles of Speckle-Based Gene RegulationNIHNational Cancer Institute2025$1,749,106August 5, 2025July 31, 2028ALEXANDER, KATHERINE ANNreporter.nih.gov
Targeting allosteric scaffolding functions of Aurora kinase A in cancerNIHNational Cancer Institute2021 to 2025$1,740,140April 1, 2021March 31, 2027LEVINSON, NICHOLAS MARKreporter.nih.gov
Overcoming Leukemia Chemoresistance in the Central Nervous SystemNIHNational Cancer Institute2021 to 2025$1,736,717March 4, 2020March 31, 2027GORDON, PETER Mreporter.nih.gov
Characterizing determinants of primary KSHV infection among children and adolescents in UgandaNIHNational Cancer Institute2021 to 2023$1,735,566September 13, 2019August 31, 2025PHIPPS, WARRENreporter.nih.gov
Discovery of small molecules targeting the histone acetylation reader ENLNIHNational Cancer Institute2021 to 2024$1,734,163December 15, 2020December 1, 2025WEN, HONGreporter.nih.gov
Cancer Immunotherapy Trials Network Central Operations and Statistical CenterNIHNational Cancer Institute2021$1,731,885September 22, 2010March 31, 2022DAVIDSON, NANCY ELLENreporter.nih.gov
Heterozygous KMT2D Loss and MedulloblastomaNIHNational Cancer Institute2022 to 2025$1,730,741August 9, 2022July 31, 2027LEE, MIN GYUreporter.nih.gov
Iomab-ACT: A phase I/II study of 131-I apamistamab targeted lymphodepletion followed by CD19-targeted CAR T-cell therapy for patients with relapsed or refractory B-ALL or DLBCLNIHNational Cancer Institute2023 to 2024$1,730,616September 9, 2020July 31, 2025DESAI, AVINASHreporter.nih.gov
Clinical, molecular, and immune characterization of naturally occurring osteosarcoma in dogsNIHNational Cancer Institute2023 to 2025$1,729,726August 1, 2023July 31, 2028REBHUN, ROBERT Breporter.nih.gov
Mechanisms of venetoclax combination activity in acute myeloid leukemiaNIHNational Cancer Institute2021 to 2025$1,729,672June 2, 2021May 31, 2026TYNER, JEFFREY WALLACEreporter.nih.gov
PEDIATRIC ONCOLOGY EDUCATION (YEARS 38 - 42)NIHNational Cancer Institute2022 to 2025$1,728,000July 1, 1978April 30, 2027GRONEMEYER, SUZANNE A.reporter.nih.gov
Optimizing Carbon Ion Therapy for Pediatric CNS TumorsNIHNational Cancer Institute2023 to 2025$1,727,977September 18, 2023August 31, 2028ELEY, JOHN G.reporter.nih.gov
Intraoperative dual-labeled molecular tracer to improve surgery on neuroblastomaNIHNational Cancer Institute2023 to 2025$1,724,101July 1, 2023June 30, 2028MALEK, MARCUS M.reporter.nih.gov
Chemo-radio immunotherapy for pediatric brain tumorsNIHNational Cancer Institute2021 to 2023$1,721,832September 1, 2019August 31, 2025MUNN, DAVID H.reporter.nih.gov
Targeting EGFR/FOXG1-mediated resistance to ONC201 in H3K27M-mutant diffuse midline gliomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,721,391February 1, 2022January 31, 2027KOSCHMANN, CARL Jreporter.nih.gov
Novel Small-Molecule Probes Targeting Oncogenic Fusion MLL in Pediatric LeukemiaNIHNational Cancer Institute2022 to 2025$1,719,656December 10, 2021November 30, 2026SONG, YONGCHENGreporter.nih.gov
Genetics and epigenetics of pediatric germ cell tumorsNIHNational Cancer Institute2022 to 2025$1,715,480September 1, 2022August 31, 2027POYNTER, JENNY N.reporter.nih.gov
Understanding the immune response changes to clinical interventions for Epstein-Barr virus infection prior to lymphoma development in children after organ transplants (UNEARTH)NIHNational Cancer Institute2024 to 2025$1,709,513September 1, 2023August 31, 2028DHARNIDHARKA, VIKAS R.reporter.nih.gov
Metabolic adaptation in lymphoid malignanciesNIHNational Cancer Institute2021 to 2024$1,709,232December 1, 2019November 30, 2025ZHANG, JIreporter.nih.gov
Identifying and Targeting the Drivers of Pediatric Brain TumorsNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,704,698October 1, 2022April 30, 2029WECHSLER-REYA, ROBERT J.reporter.nih.gov
Novel functions of CDK6 in T-cell leukemia progressionNIHNational Cancer Institute2021 to 2025$1,701,837August 1, 2021July 31, 2026WANG, HAIZHENreporter.nih.gov
Engineered Ensemble Nanoimmunotherapies for CancerNIHNational Cancer Institute2021 to 2024$1,699,559February 1, 2023January 31, 2025FERNANDES, ROHANreporter.nih.gov
Role of Protein Arginine Methyltransferase 9 in Acute Myeloid Leukemia MaintenanceNIHNational Cancer Institute2021 to 2024$1,695,047March 1, 2020February 28, 2025LI, LINGreporter.nih.gov
Role of the SWI/SNF complex in tumor suppressionNIHNational Cancer Institute2021 to 2025$1,690,815July 1, 2013January 31, 2029ROBERTS, CHARLESreporter.nih.gov
Development of AMPK Inhibitors for the treatment of leukemiaNIHNational Cancer Institute2021 to 2025$1,690,278July 1, 2021June 30, 2027REIGAN, PHILIPreporter.nih.gov
The role of inflammation in the regulation of immune response in acute myeloid leukemiaNIHNational Cancer Institute2023 to 2025$1,687,418July 6, 2023June 30, 2028AIFANTIS, IANNISreporter.nih.gov
Combinational Targeting the Feed-forward Epigenetic Circuitry in Mixed Lineage LeukemiaNIHNational Cancer Institute2021 to 2025$1,684,284December 1, 2023February 16, 2025CHEN, CHUN-WEI DAVIDreporter.nih.gov
Novel Immunomodulation and Facilitation of “Suppression Proof” CAR NK cell against Ewing sarcomaNIHNational Cancer Institute2021 to 2023$1,683,725September 1, 2023August 31, 2025CRIPE, TIMOTHY Preporter.nih.gov
Determining the Role and Targeting potential of Serine Metabolism in aggressive sub-types of Acute Myeloid LeukemiaNIHNational Cancer Institute2023 to 2025$1,682,310March 1, 2023February 29, 2028SYKES, STEPHEN MATTHEWreporter.nih.gov
Validation of an aqueous humor liquid biopsy for molecular prognostication and monitoring of children with retinoblastoma.NIHNational Cancer Institute2023 to 2025$1,681,542August 1, 2023July 31, 2028BERRY, JESSE Lreporter.nih.gov
Understanding Infantile Rhabdomyosarcoma Biology and Therapeutic TargetsNIHNational Cancer Institute2022 to 2025$1,673,106September 23, 2022August 31, 2027KENDALL, GENEVIEVE CLAIREreporter.nih.gov
HPV, HIV and Oral Microbiota Interplay in Nigerian Youth (HOMINY)NIHNational Institute of Dental & Craniofacial Research2022 to 2023$1,672,805August 1, 2022July 31, 2024COKER, MODUPEreporter.nih.gov
Tracking Therapy-Resistant Alterations in Childhood Acute Lymphoblastic LeukemiaNIHNational Cancer Institute2022 to 2025$1,672,253August 1, 2022July 31, 2027MA, XIAOTUreporter.nih.gov
Self-Management of Adolescent and Young Adult Survivors of Childhood CancerNIHNational Institute of Nursing Research2021 to 2023$1,670,597December 28, 2018November 30, 2025SCHWARTZ, LISA Areporter.nih.gov
The function and underlying mechanism of TET1 in myelodysplastic syndromesNIHNational Institute of Diabetes and Digestive and Kidney Diseases2021 to 2023$1,663,013March 10, 2020December 31, 2023CHEN, JIANJUNreporter.nih.gov
NP855 for Targeting Thyrointegrin αvβ3 receptors and Norepinephrine Transporter in Neuroblastoma ManagementNIHNational Cancer Institute2024 to 2025$1,661,800September 19, 2024August 31, 2027DAVIS, PAULreporter.nih.gov
ASO and shRNA for targeting the oncogenic transcript driving fibrolamellar hepatocellular carcinomaNIHNational Cancer Institute2021 to 2024$1,659,105June 1, 2020May 31, 2025SIMON, SANFORD Mreporter.nih.gov
Enhancer Dysregulation in AMLNIHNational Cancer Institute2021 to 2023$1,657,025March 1, 2019February 28, 2025DOU, YALIreporter.nih.gov
Leveraging Tumor Suppressor Inactivation for Osteosarcoma TherapyNIHNational Cancer Institute2021 to 2024$1,655,878July 1, 2021June 30, 2026HOANG, BANG Hreporter.nih.gov
Molecular epidemiology of acute lymphoblastic leukemia in children with Down syndromeNIHNational Cancer Institute2023 to 2024$1,645,759August 3, 2020July 31, 2025RABIN, KAREN Rreporter.nih.gov
Deconvoluting the Ewing sarcoma genetic program using ancestry-informed human iPSC modelingNIHNational Cancer Institute2023 to 2025$1,644,656April 7, 2023March 31, 2028WEBBER, BEAU RICHARDreporter.nih.gov
Regulation, function, and the therapeutic potential of an oncogenic long noncoding RNA lnc-HLX-2-7 in group 3 medulloblastomasNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,640,984July 15, 2022June 30, 2027PERERA, RANJAN JOSEPHreporter.nih.gov
Pneumatic Drill and Robot for MRI-Guided Pediatrics Long Bone BiopsyNIHNational Cancer Institute2021 to 2023$1,638,868March 1, 2020August 31, 2025CLEARY, KEVIN R.reporter.nih.gov
Mechanisms of resistance to WEE1 inhibition in Myc driven medulloblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,638,259April 1, 2015November 30, 2026VIBHAKAR, RAJEEVreporter.nih.gov
Admixture analysis of acute lymphoblastic leukemia in African American children: the ADMIRAL StudyNIHNational Cancer Institute2021 to 2024$1,638,139August 1, 2020July 31, 2025SPECTOR, LOGAN G.reporter.nih.gov
Enhanced radiotherapy for pediatric glioma via synthetic lethal vulnerabilitiesNIHNational Cancer Institute2024 to 2025$1,637,935July 1, 2024June 30, 2026CHOWDHURY, DIPANJANreporter.nih.gov
The Role of Immature Tumor Subpopulations In Pediatric RhabdomyosarcomaNIHNational Cancer Institute2022 to 2025$1,636,159March 4, 2022February 28, 2027CHEN, XIANGreporter.nih.gov
BET bromodomain inhibition as targeted therapy in acute myeloid leukemiaNIHNational Cancer Institute2021 to 2023$1,634,470April 1, 2013November 30, 2024VAKOC, CHRISTOPHERreporter.nih.gov
Cellular and Molecular mechanisms of ATRA inhibition of osteoblast-induced MDS developmentNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2021 to 2025$1,628,178February 15, 2021November 30, 2025KOUSTENI, STAVROULAreporter.nih.gov
Using Information Technology to Improve Outcomes for Children Living with CancerNIHNational Cancer Institute2021 to 2024$1,628,167September 20, 2019December 31, 2025LAI, JIN-SHEIreporter.nih.gov
Non-invasively extendable megaprosthesisNIHNational Institute of Arthritis and Musculoskeletal and Skin Diseases2023 to 2024$1,621,828September 25, 2023July 31, 2026GORDON, JEFFREY DAVIDreporter.nih.gov
Lineage-specific signaling and targeting of PI3K gamma in myeloid malignanciesNIHNational Cancer Institute2022 to 2025$1,620,456April 1, 2022January 31, 2027WOOD, KRIS C.reporter.nih.gov
Identifying host factors that block engraftment and progression of transmissible cancer as a model of AMLNIHNational Cancer Institute2022 to 2025$1,617,947January 1, 2022December 31, 2026METZGER, MICHAEL JEFFREYreporter.nih.gov
Investigating the role of dysfunctional histone H3.3 in driving early neuronal development and pediatric high-grade gliomasNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,617,011June 1, 2021November 30, 2026HU, JIANreporter.nih.gov
A web-based patient-reported symptom monitoring and self-management portal for adolescent and young adult breast cancer survivorsNIHNational Cancer Institute2023 to 2024$1,613,871September 18, 2020August 31, 2025PARTRIDGE, ANN Hreporter.nih.gov
The Role of GABA Transaminase ABAT in Pediatric Brain Tumor Medulloblastoma Development and SpreadNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,613,377June 1, 2023February 28, 2028NEMAN-EBRAHIM, JOSHreporter.nih.gov
Modeling Retinoblastoma Initiation Using 3D-Retinal OrganoidsNIHNational Cancer Institute2021 to 2024$1,605,471May 15, 2020April 30, 2026DYER, MICHAEL Areporter.nih.gov
Dysregulated transcription processes in Ewing sarcomaNIHNational Cancer Institute2021 to 2024$1,602,211May 1, 2020April 30, 2026BISHOP, ALEXANDER JAMESreporter.nih.gov
Novel targeted therapy to reduce health disparities in pediatric leukemiaNIHNational Cancer Institute2023 to 2025$1,596,016June 1, 2023May 31, 2028DOVAT, SINISAreporter.nih.gov
Exploring microRNA degradation in T-cell acute lymphoblastic leukemiaNIHNational Cancer Institute2023 to 2025$1,594,435July 1, 2023June 30, 2028XIE, MINGYIreporter.nih.gov
Cell lineage as an indicator of immune response in neuroblastomaNIHNational Cancer Institute2022 to 2025$1,593,136June 16, 2022May 31, 2027GEORGE, RANI E.reporter.nih.gov
Mechanisms of aggressive Rhabdomyosarcoma.NIHNational Cancer Institute2023 to 2025$1,592,991March 1, 2023February 29, 2028LANGENAU, DAVID MICHAELreporter.nih.gov
Mechanisms and Modeling of Neuroblastoma-Associated ATRX AlterationsNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,591,835March 1, 2020December 31, 2024BERNSTEIN, EMILYreporter.nih.gov
Chemical Genetic Approaches to Study Chromatin ComplexesNIHNational Cancer Institute2023 to 2025$1,590,400May 3, 2023April 30, 2028LIAU, BRIANreporter.nih.gov
Regulation of Angpt1 and DIPG blood-brain barrier integrity by H3K27M mutationsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,587,577December 15, 2021November 30, 2026PHOENIX, TIMOTHY Nreporter.nih.gov
Developing and validating race-specific cardiomyopathy risk prediction models in African American survivors of childhood cancerNIHNational Heart, Lung, and Blood Institute2024 to 2025$1,586,554May 15, 2024April 30, 2028SAPKOTA, YADAVreporter.nih.gov
Role of UHRF1 in osteosarcoma and its relationship to RBNIHNational Cancer Institute2021 to 2023$1,573,144June 1, 2019May 31, 2025BENAVENTE, CLAUDIA ANDREAreporter.nih.gov
Mechanism(s) of TAL1- and NOTCH1-mediated LeukemogenesisNIHNational Cancer Institute2022 to 2025$1,571,361August 1, 2004June 30, 2027KELLIHER, MICHELLE ALICEreporter.nih.gov
Mechanisms of immunosuppression in the development and progression of renal disease in Tuberous Sclerosis ComplexNIHNational Institute of Diabetes and Digestive and Kidney Diseases2023 to 2025$1,569,410April 5, 2023March 31, 2028HENSKE, ELIZABETH Preporter.nih.gov
Role of meningeal lymphatic vasculature in neuroimmune communication developmentNIHNational Institute of Neurological Disorders and Stroke2023 to 2025$1,566,735February 15, 2023January 31, 2028THOMAS, JEAN-LEONreporter.nih.gov
BCL11B activation as an approach for enhancing the efficacy of immunotherapyNIHNational Institute of Allergy and Infectious Diseases2021 to 2024$1,566,114February 11, 2021July 1, 2024PAREKH, CHINTANreporter.nih.gov
Nongenotoxic conditioning for gene therapy and allogeneic transplantation in Fanconi anemiaNIHNational Heart, Lung, and Blood Institute2022 to 2023$1,563,164December 20, 2019November 30, 2025KIEM, HANS-PETERreporter.nih.gov
Oncogenic tyrosine kinases inhibitors abrogate DNA repair and sensitive leukemias to PARP inhibitorsNIHNational Cancer Institute2021 to 2024$1,562,631April 1, 2020March 31, 2026SKORSKI, TOMASZreporter.nih.gov
Heat Shock Transcription Factor 1 Specifically Regulates AML Stem Cell Self-RenewalNIHNational Cancer Institute2021 to 2024$1,558,730December 15, 2019May 31, 2025ZHAO, CHENreporter.nih.gov
Sonic Hedgehog Signaling in Neocortical Growth and FoldingNIHNational Institute of Neurological Disorders and Stroke2021 to 2025$1,554,342September 30, 2017December 31, 2028HAN, YOUNG-GOOreporter.nih.gov
GEARBOx - a multisite clinical trial matching tool for children with relapsed or refractory cancerNIHNational Cancer Institute2022 to 2024$1,551,911September 21, 2022August 31, 2025VOLCHENBOUM, SAMUELreporter.nih.gov
Targeting DNA repair to eradicate TKi-refractory/resistant CML and Ph+ALLNIHNational Cancer Institute2021 to 2024$1,543,188August 12, 2014February 28, 2026SKORSKI, TOMASZreporter.nih.gov
Mitochondrial NAD+ in Acute Myeloid LeukemiasNIHNational Cancer Institute2023 to 2025$1,541,490August 24, 2023July 31, 2028CAMBRONNE, XIAOLU ANGreporter.nih.gov
Decreasing Cardiometabolic Risk in Survivors of Childhood Cancer: Survivors engaged in Time-Restricted EatiNG after THerapy (STRENGTH)NIHNational Cancer Institute2024 to 2025$1,538,728September 1, 2024August 31, 2029FRIEDMAN, DANIELLEreporter.nih.gov
Defining the microenvironment that will enable a long-term bioprosthetic ovary transplantNIHEunice Kennedy Shriver National Institute of Child Health & Human Development2021 to 2025$1,533,689May 1, 2021April 30, 2027LARONDA, MONICA Mreporter.nih.gov
TAM receptor inhibition in NF1-associated peripheral nerve sheath tumorsNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,531,238July 1, 2022June 30, 2027CLAPP, DAVID Wreporter.nih.gov
Precision Targeting of Myeloid Src-family Kinases in Acute Myelogenous LeukemiaNIHNational Cancer Institute2021 to 2023$1,530,763July 15, 2019June 30, 2025SMITHGALL, THOMAS E.reporter.nih.gov
Detecting DICER1: A global partnership to cure pediatric lung cancerNIHNational Cancer Institute2021 to 2025$1,529,269February 15, 2020January 31, 2026SCHULTZ, KRIS ANN PINEKENSTEINreporter.nih.gov
Dependency of AML on CARM1 activityNIHNational Cancer Institute2021 to 2024$1,525,290July 1, 2020June 30, 2026NIMER, STEPHEN D.reporter.nih.gov
Role of TFEB and TFE3 in Tuberous Sclerosis Complex (TSC) Kidney DiseaseNIHNational Institute of Diabetes and Digestive and Kidney Diseases2022 to 2025$1,521,682September 1, 2022April 30, 2026HENSKE, ELIZABETH Preporter.nih.gov
Targeting the Microenvironment/Oncogene Cooperation to treat poor prognosis T-ALLNIHNational Cancer Institute2023 to 2025$1,520,378March 9, 2023February 29, 2028CARLESSO, NADIAreporter.nih.gov
Molecular mechanisms of nucleic acid machinesNIHNational Institute of General Medical Sciences2021 to 2024$1,520,008June 1, 2020May 31, 2026ENEMARK, ERICreporter.nih.gov
Targeting Shared Vulnerabilities in Alternate Telomere Lengthening (ALT) CancersNIHNational Cancer Institute2022 to 2025$1,509,510January 1, 2022August 31, 2027REYNOLDS, CHARLES PATRICKreporter.nih.gov
Trajectory of epigenetic aging and health outcomes in childhood cancer survivorsNIHNational Cancer Institute2024 to 2025$1,509,154May 1, 2024April 30, 2026NESS, KIRSTEN KIMBERLIEreporter.nih.gov
Molecular understanding of leukemic bone marrow cytokine-Ras signals and metabolic dependenceNIHNational Cancer Institute2022 to 2025$1,507,401July 1, 2015December 31, 2026ROOSE, JEROENreporter.nih.gov
Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell developmentNIHNational Institute of Allergy and Infectious Diseases2021 to 2023$1,506,076June 1, 2019May 31, 2025CHIANG, MARK Yreporter.nih.gov
Identifying opportunities for extracellular inhibition of ALK signalingNIHNational Cancer Institute2021 to 2024$1,505,804September 1, 2020May 31, 2025KLEIN, DARYL EWALDreporter.nih.gov
Nanoformulated small molecule immunotherapy for SHH medulloblastomaNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,504,463January 1, 2022December 31, 2026SOKOLSKY-PAPKOV, MARINAreporter.nih.gov
Dual Kinase and LSD1 Inhibition in Acute Myeloid LeukemiaNIHNational Cancer Institute2023 to 2025$1,503,951July 13, 2023June 30, 2028BRAUN, THEODORE PAULreporter.nih.gov
Multiplex Epitope Editing to Enable Novel Immunotherapies for Acute Myeloid LeukemiaNIHNational Cancer Institute2024 to 2025$1,502,277July 3, 2024June 30, 2029GENOVESE, PIETROreporter.nih.gov
Epigenetic modulation of the TAZ-CAMTA1 transcriptional program by the Ada2a-containing histone acetyltransferase complexNIHNational Cancer Institute2021 to 2024$1,500,569December 15, 2019November 30, 2025TANAS, MUNIRreporter.nih.gov
Clinical & Mechanistic underpinnings to reducing PAX:FOXO1 for alveolar rhabdomyosarcomaNIHNational Cancer Institute2021 to 2025$1,491,560May 14, 2021April 30, 2026KELLER, CHARLESreporter.nih.gov
The Role of the CBFB-MYH11 Complex in Leukemia MaintenanceNIHNational Cancer Institute2021 to 2024$1,488,680April 1, 2020March 31, 2026HYDE, RICIA KATHERINEreporter.nih.gov
Clinical Implications of Natural Killer-derived exosomal miRNAs in NeuroblastomaNIHNational Cancer Institute2024 to 2025$1,485,440April 1, 2024March 31, 2029FABBRI, MULLERreporter.nih.gov
Gene Expression Signature Based Screening in Ewing SarcomaNIHNational Cancer Institute2021 to 2024$1,484,581February 1, 2023January 31, 2026GORDON, DAVID Jreporter.nih.gov
Regulation of the Hedgehog pathway and Medulloblastoma response to radiochemotherapyNIHNational Institute of Neurological Disorders and Stroke2022 to 2025$1,482,576April 15, 2021February 28, 2027PEI, HUADONGreporter.nih.gov
Promoting immunity against acute myeloid leukemia through Fc effector-optimized antibody inhibitory of MICA/B sheddingNIHNational Cancer Institute2023 to 2025$1,481,935February 6, 2023November 30, 2027FERRARI DE ANDRADE, LUCASreporter.nih.gov
Unravelling metabolic dependencies in H3K27M mutant DIPGNIHNational Institute of Neurological Disorders and Stroke2021 to 2024$1,480,728September 1, 2019August 31, 2029VENNETI, SRIRAMreporter.nih.gov
Dissecting and targeting canonical and non-canonical oncogenic functions of EZH2 in canerNIHNational Cancer Institute2023 to 2025$1,480,550January 1, 2022December 31, 2026WANG, G GREGreporter.nih.gov
Targeting AVIL, a novel oncogene in rhabdomyosarcomaNIHNational Cancer Institute2023 to 2025$1,479,063January 1, 2023December 31, 2027LI, HUIreporter.nih.gov
Investigating novel synthetic lethal epigenetic interactions in Acute Myeloid LeukemiaNIHNational Cancer Institute2022 to 2025$1,477,105December 13, 2021November 30, 2026SHI, JUNWEIreporter.nih.gov
Strategies to target BCR-ABL1 compound mutants in CML and Ph+ ALLNIHNational Cancer Institute2022 to 2025$1,475,782November 10, 2021June 30, 2026DEININGER, MICHAEL W.reporter.nih.gov

Organizations

OrganizationPlaceNIH awardsNIH amountNSF awardsNSF amount
Public Health InstituteOakland, CA4$185.4 million0$0
ST. Jude Children's Research HospitalMemphis, TN97$173.7 million0$0
Children's Hosp of PhiladelphiaPhiladelphia, PA44$87.7 million0$0
Harvard University D/b/a Harvard School of Public HealthBoston, MA4$73.5 million0$0
Research Inst Nationwide Children's HospColumbus, OH18$67.7 million0$0
Baylor College of MedicineHouston, TX50$66 million0$0
Dana-Farber Cancer InstBoston, MA63$58.8 million0$0
University of California, San FranciscoSan Francisco, CA49$56 million0$0
University of Southern CaliforniaLos Angeles, CA18$53.5 million0$0
Beckman Research Institute/city of HopeDuarte, CA39$48.3 million0$0
University of Michigan at Ann ArborAnn Arbor, MI44$44.5 million0$0
Sloan-Kettering Inst Can ResearchNew York, NY36$44 million0$0
New York University School of MedicineNew York, NY17$41.2 million0$0
Stanford UniversityStanford, CA33$39.9 million0$0
University of MinnesotaMinneapolis, MN34$39.7 million0$0
University of ChicagoChicago, IL13$35.5 million0$0
Fred Hutchinson Cancer CenterSeattle, WA23$34.6 million0$0
University of Colorado DenverAurora, CO33$31.5 million0$0
University of PennsylvaniaPhiladelphia, PA38$30.6 million0$0
Johns Hopkins UniversityBaltimore, MD26$29.7 million0$0
Icahn School of Medicine at Mount SinaiNew York, NY19$29 million0$0
Washington UniversitySaint Louis, MO31$27.1 million0$0
Cincinnati Childrens Hosp Med CTRCincinnati, OH25$26.9 million0$0
Children's Hospital of Los AngelesLos Angeles, CA18$26.6 million0$0
Columbia University Health SciencesNew York, NY25$26.3 million0$0
Seattle Children's HospitalSeattle, WA26$25.3 million0$0
University of Nebraska Medical CenterOmaha, NE11$24.9 million0$0
University of TX MD Anderson Can CTRHouston, TX27$24.5 million0$0
University of California, San DiegoLa Jolla, CA21$23.6 million0$0
University of FloridaGainesville, FL19$23.2 million0$0
Oregon Health & Science UniversityPortland, OR26$21.9 million0$0
Yale UniversityNew Haven, CT16$20.1 million0$0
Northwestern University at ChicagoChicago, IL16$19.8 million0$0
University of Texas HLTH Science CenterSan Antonio, TX14$19.2 million0$0
Emory UniversityAtlanta, GA34$18.1 million0$0
Albert Einstein College of MedicineBronx, NY10$17.2 million0$0
Children's Research InstituteWashington, DC15$16.6 million0$0
University of Pittsburgh at PittsburghPittsburgh, PA20$16.3 million0$0
Jackson LaboratoryBar Harbor, ME3$16.3 million0$0
University of Alabama at BirminghamBirmingham, AL12$15.9 million0$0
University of California-Santa CruzSanta Cruz, CA2$15.8 million0$0
Univ of North Carolina Chapel HillChapel Hill, NC23$15.6 million0$0
Ohio State UniversityColumbus, OH17$15.5 million0$0
Vanderbilt University Medical CenterNashville, TN8$14.9 million0$0
University of UtahSalt Lake City, UT18$14.9 million0$0
Massachusetts General HospitalBoston, MA17$14.8 million0$0
Indiana University IndianapolisIndianapolis, IN17$14.6 million0$0
North American Assn/central Cancer RegSpringfield, IL2$13.6 million0$0
Duke UniversityDurham, NC24$13.4 million0$0
Rutgers Biomedical and Health SciencesNewark, NJ12$13.3 million0$0
Georgetown UniversityWashington, DC12$13.2 million0$0
Boston Children's HospitalBoston, MA10$12.9 million0$0
Ut Southwestern Medical CenterDallas, TX19$12.1 million0$0
University of California-IrvineIrvine, CA8$11.8 million0$0
Brigham and Women's HospitalBoston, MA8$11.6 million0$0
Univ of Massachusetts Med SCH WorcesterWorcester, MA10$11.4 million0$0
Corewell HealthGrand Rapids, MI1$11.4 million0$0
Mayo Clinic RochesterRochester, MN13$11.3 million0$0
HudsonAlpha Institute for BiotechnologyHuntsville, AL1$11.3 million0$0
Roswell Park Cancer Institute CorpBuffalo, NY8$10.9 million0$0
Lurie Children's Hospital of ChicagoChicago, IL10$10.5 million0$0
Massachusetts Institute of TechnologyCambridge, MA6$9.8 million0$0
Aurora Health Care, Inc.Milwaukee, WI1$9.6 million0$0
Kaiser Foundation Research InstituteOakland, CA2$9.1 million0$0
Nemours Children's Hospital, DelawareWilmington, DE4$8.8 million0$0
University of California Los AngelesLos Angeles, CA8$8.5 million0$0
Virginia Commonwealth UniversityRichmond, VA9$8.4 million0$0
Westat, Inc.Bethesda, MD1$8.2 million0$0
University of Wisconsin-MadisonMadison, WI13$7.8 million0$0
Temple Univ of the CommonwealthPhiladelphia, PA5$7.8 million0$0
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA7$7.7 million0$0
Cold Spring Harbor LaboratoryCold Spring Harbor, NY8$7.5 million0$0
University of Miami School of MedicineCoral Gables, FL10$7.5 million0$0
Pennsylvania State Univ Hershey Med CTRHershey, PA6$7.4 million0$0
Case Western Reserve UniversityCleveland, OH13$7.4 million0$0
Thomas Jefferson UniversityPhiladelphia, PA6$7.3 million0$0
University of VirginiaCharlottesville, VA10$7.1 million0$0
Fred Hutchinson Cancer Research CenterSeattle, WA17$6.8 million0$0
Weill Medical Coll of Cornell UnivNew York, NY8$6.6 million0$0
University of CincinnatiCincinnati, OH9$6.2 million0$0
University of California at DavisDavis, CA8$6.2 million0$0
Versiti Blood Health, Inc.Milwaukee, WI6$6.2 million0$0
Vanderbilt UniversityNashville, TN5$5.6 million0$0
Wake Forest University Health SciencesWinston-Salem, NC7$5.4 million0$0
Medical University of South CarolinaCharleston, SC7$5.4 million0$0
Texas Tech University Health Scis CenterLubbock, TX4$5.2 million0$0
MainehealthPortland, ME1$5.1 million0$0
University of IowaIowa City, IA3$5.1 million0$0
Comprehensive Cancer Center/ Univ/prSan Juan, PR1$4.9 million0$0
University of Texas HLTH Sci CTR HoustonHouston, TX7$4.5 million0$0
Cog Research Foundation, LLCArcadia, CA1$4.4 million0$0
University of KentuckyLexington, KY5$4.2 million0$0
Twinstrand Biosciences, Inc.Seattle, WA1$4 million0$0
University of California-BerkeleyBerkeley, CA5$3.9 million0$0
University of ArizonaTucson, AZ3$3.9 million0$0
University of South FloridaTampa, FL3$3.9 million0$0
University College LondonLondon2$3.7 million0$0
University of WashingtonSeattle, WA4$3.7 million0$0
Florida Assn of Pediatric Tumor ProgTampa, FL1$3.5 million0$0
Tufts University BostonBoston, MA3$3.4 million0$0

Funding by fiscal year

Fiscal yearNIH awardsNIH amountNSF awardsNSF amount
2025880$519,368,0070$0
2024942$507,315,1150$0
2023910$488,601,9570$0
2022898$454,265,2110$0
2021830$430,105,5010$0

Open federal funding opportunities

From Grants.gov: notices that funded awards in this table, and open notices on the same agency and assistance listing.

Open opportunityNumberAgencyListingClosesAward ceilingWhy it matches
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)PA-24-254NIHJuly 12, 2027Not listedNotice number printed on 16 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)PA-24-181NIHMay 8, 2027Not listedNotice number printed on 3 awards here
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)PA-24-182NIHMay 8, 2027Not listedNotice number printed on 1 award here
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)PAR-27-089NIH93.395November 2, 2026Not listedSame assistance listing 93.395 as 416 awards here
Precision Approaches in Radiation Synthetic Combinations (PAIRS, RP1 Clinical Trial Optional)PAR-26-152NIH93.395November 11, 2026Not listedSame assistance listing 93.395 as 416 awards here
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)PAR-27-088NIH93.395November 20, 2026Not listedSame assistance listing 93.395 as 416 awards here
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)PAR-24-214NIH93.395January 7, 2027$375,000Same assistance listing 93.395 as 416 awards here
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)PAR-25-079NIH93.395January 7, 2027$500,000Same assistance listing 93.395 as 416 awards here
National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)PAR-25-081NIH93.395January 7, 2027$499,999Same assistance listing 93.395 as 416 awards here
Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)RFA-CA-27-005NIH93.395January 11, 2027$700,000Same assistance listing 93.395 as 416 awards here
Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)PAR-27-009NIH93.395January 25, 2027Not listedSame assistance listing 93.395 as 416 awards here
Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)RFA-CA-26-010NIH93.395January 25, 2027Not listedSame assistance listing 93.395 as 416 awards here
Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)RFA-CA-27-003NIH93.395January 25, 2027Not listedSame assistance listing 93.395 as 416 awards here
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)PA-27-100NIH93.395April 5, 2027Not listedSame assistance listing 93.395 as 416 awards here
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)PA-27-102NIH93.395April 5, 2027Not listedSame assistance listing 93.395 as 416 awards here
Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)RFA-CA-28-003NIH93.395June 11, 2027$600,000Same assistance listing 93.395 as 416 awards here
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)PA-24-253NIH93.395July 17, 2027Not listedSame assistance listing 93.395 as 416 awards here
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)PA-25-080NIH93.395September 7, 2027Not listedSame assistance listing 93.395 as 416 awards here
Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)PAR-24-325NIH93.395September 7, 2027Not listedSame assistance listing 93.395 as 416 awards here
Investigator-Focused Award (Parent R35)PAR-28-037NIH93.395October 4, 2027Not listedSame assistance listing 93.395 as 416 awards here

Updated November 3, 2026. Read from NIH RePORTER ExPORTER and NSF Award Search. Published by NIH and NSF as U.S. government data. NIH awards are fiscal years 2021 to 2025 (NIH files published to 2026-07-09); NSF awards are fiscal years 2022 to 2026 (NSF files published to 2026-11-02). NIH amounts are the total cost of each fiscal year in the window; NSF amounts are the funds obligated in the window. Organizations are matched on the UEI. Open opportunities come from Grants.gov and match on agency and assistance listing number, and on the notice number NIH prints on an award. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.